OR51B2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OR51B2
Entrez Gene ID	79345
Full Name	olfactory receptor family 51 subfamily B member 2 (gene/pseudogene)
Synonyms	HOR5'Beta3,OR51B1P
General protein information	Preferred Names olfactory receptor family 51 subfamily B member 2 (gene/pseudogene) Names olfactory receptor 51B2 odorant receptor HOR5'beta3 olfactory receptor 51B1 olfactory receptor, family 51, subfamily B, member 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p15.4
Summary	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_033180.4	NP_149420.4	olfactory receptor 51B2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC745965	XP_001162165.1
Canis lupus familiaris (dog)	LOC485258	XP_853036.2
Rattus norvegicus (Norway rat)	Olr131	NP_001001285.1
Homo sapiens (human)	OR51B2	NP_149420.4
Mus musculus (house mouse)	Olfr64	NP_038645.2

Gene Ontology
Bibliography

Related articles in PubMed

Personal receptor repertoires: olfaction as a model.
Olender T, Waszak SM, Viavant M, Khen M, Ben-Asher E, Reyes A, Nativ N, Wysocki CJ, Ge D, Lancet D
BMC genomics13414(2012 Aug)

A probabilistic classifier for olfactory receptor pseudogenes.
Menashe I, Aloni R, Lancet D
BMC bioinformatics7393(2006 Aug)

DEFOG: a practical scheme for deciphering families of genes.
Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R
Genomics80(3)295-302(2002 Sep)

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.
Bulger M, Bender MA, van Doorninck JH, Wertman B, Farrell CM, Felsenfeld G, Groudine M, Hardison R
Proceedings of the National Academy of Sciences of the United States of America97(26)14560-5(2000 Dec)

Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.
Bulger M, van Doorninck JH, Saitoh N, Telling A, Farrell C, Bender MA, Felsenfeld G, Axel R, Groudine M, von Doorninck JH
Proceedings of the National Academy of Sciences of the United States of America96(9)5129-34(1999 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following OR51B2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OR51B2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu30575	NM_033180.4 Latest version!	Homo sapiens olfactory receptor family 51 subfamily B member 2 (gene/pseudogene) (OR51B2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OR51B2 ( NM_033180.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_149420.4 Homo sapiens olfactory receptor family 51 subfamily B member 2 (gene/pseudogene) (OR51B2), mRNA.

Price & Availability↑

CloneID	OHu30575
Clone ID Related Accession (Same CDS sequence)	NM_033180.4
Accession Version	NM_033180.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	olfactory receptor 51B2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC117461.1 and AC104389.8. On Sep 28, 2007 this sequence version replaced NM_033180.3. Sequence Note: This gene is a segregating pseudogene. This RefSeq represents the protein encoded by the reference genome allele, which is predicted to be non-functional as an olfactory receptor according to the Classifier for Olfactory Receptor Pseudogenes. This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript is intronless :: BC117461.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 22908908 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGTGGCCCA ATATTACTGC AGCCCCTTTT TTGCTGACTG GCTTTCCAGG GCTGGAGGCA 
GCTCATCACT GGATCTCCAT CCCCTTCTTT GCTGTTTATG TGTGCATCCT TCTGGGCAAT 
GGCATGCTCC TCTACCTCAT CAAGCATGAC CACAGTCTTC ATGAGCCCAT GTACTACTTC 
CTCACCATGC TGGCAGGCAC AGACCTCATG GTGACATTGA CCACGATGCC TACTGTAATG 
GGCATCCTAT GGGTGAATCA CAGGGAGATT AGCAGTGTGG GCTGCTTCCT ACAGGCTTAC 
TTTATTCACT CCCTTTCTGT TGTGGAATCA GGTTCCCTCC TGGCAATGGC ATATGATTGT 
TTCATTGCCA TCCGCAATCC TTTGAGATAT GCTTCCATTC TCACCAATAC TAGAGTCATA 
GCGTTAGGAG TGGGAGTGTT TCTAAGGGGT TTTGTATCCA TCCTGCCTGT AATTTTGCGT 
CTTTTTTCAT TTTCATATTG CAAATCTCAT GTTATCACAC GTGCTTTCTG CCTCCACCAA 
GAAATCATGA GACTGGCTTG TGCTGACATA ACTTTCAATA GACTTTACCC TGTAATTTTG 
ATCTCTTTAA CAATCTTCCT AGACTGTCTG ATCATCCTCT TCTCCTATAT TCTAATTCTT 
AATACTGTCA TAGGCATTGC TTCTGGTGAA GAGAGAGCCA AAGCCCTCAA TACCTGTATC 
TCCCACATTA GTTGTGTTCT TATCTTCTAT GTTACAGTGA TGGGTTTGAC ATTCATTTAC 
AGATTTGGGA AGAATGTGCC AGAGGTTGTC CACATTATCA TGAGTTACAT CTACTTCCTC 
TTTCCTCCTT TAATGAACCC TGTCATCTAC AGCATCAAAA CCAAGCAAAT ACAATATGGC 
ATTATCCGCC TTTTATCTAA ACATAGGTTT AGTAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_149420.4
CDS	56..994
Translation	MWPNITAAPFLLTGFPGLEAAHHWISIPFFAVYVCILLGNGMLLYLIKHDHSLHEPMYYFLTMLAGTDLMVTLTTMPTVMGILWVNHREISSVGCFLQAYFIHSLSVVESGSLLAMAYDCFIAIRNPLRYASILTNTRVIALGVGVFLRGFVSILPVILRLFSFSYCKSHVITRAFCLHQEIMRLACADITFNRLYPVILISLTIFLDCLIILFSYILILNTVIGIASGEERAKALNTCISHISCVLIFYVTVMGLTFIYRFGKNVPEVVHIIMSYIYFLFPPLMNPVIYSIKTKQIQYGIIRLLSKHRFSS

Target ORF information:

RefSeq Version	NM_033180.4
Organism	Homo sapiens(human)
Definition	Homo sapiens olfactory receptor family 51 subfamily B member 2 (gene/pseudogene) (OR51B2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033180.4

ORF Insert Sequence:

ATGTGGCCCA ATATTACTGC AGCCCCTTTT TTGCTGACTG GCTTTCCAGG GCTGGAGGCA 
GCTCATCACT GGATCTCCAT CCCCTTCTTT GCTGTTTATG TGTGCATCCT TCTGGGCAAT 
GGCATGCTCC TCTACCTCAT CAAGCATGAC CACAGTCTTC ATGAGCCCAT GTACTACTTC 
CTCACCATGC TGGCAGGCAC AGACCTCATG GTGACATTGA CCACGATGCC TACTGTAATG 
GGCATCCTAT GGGTGAATCA CAGGGAGATT AGCAGTGTGG GCTGCTTCCT ACAGGCTTAC 
TTTATTCACT CCCTTTCTGT TGTGGAATCA GGTTCCCTCC TGGCAATGGC ATATGATTGT 
TTCATTGCCA TCCGCAATCC TTTGAGATAT GCTTCCATTC TCACCAATAC TAGAGTCATA 
GCGTTAGGAG TGGGAGTGTT TCTAAGGGGT TTTGTATCCA TCCTGCCTGT AATTTTGCGT 
CTTTTTTCAT TTTCATATTG CAAATCTCAT GTTATCACAC GTGCTTTCTG CCTCCACCAA 
GAAATCATGA GACTGGCTTG TGCTGACATA ACTTTCAATA GACTTTACCC TGTAATTTTG 
ATCTCTTTAA CAATCTTCCT AGACTGTCTG ATCATCCTCT TCTCCTATAT TCTAATTCTT 
AATACTGTCA TAGGCATTGC TTCTGGTGAA GAGAGAGCCA AAGCCCTCAA TACCTGTATC 
TCCCACATTA GTTGTGTTCT TATCTTCTAT GTTACAGTGA TGGGTTTGAC ATTCATTTAC 
AGATTTGGGA AGAATGTGCC AGAGGTTGTC CACATTATCA TGAGTTACAT CTACTTCCTC 
TTTCCTCCTT TAATGAACCC TGTCATCTAC AGCATCAAAA CCAAGCAAAT ACAATATGGC 
ATTATCCGCC TTTTATCTAA ACATAGGTTT AGTAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Personal receptor repertoires: olfaction as a model.
BMC genomics13414(2012 Aug)
Olender T,Waszak SM,Viavant M,Khen M,Ben-Asher E,Reyes A,Nativ N,Wysocki CJ,Ge D,Lancet D

A probabilistic classifier for olfactory receptor pseudogenes.
BMC bioinformatics7393(2006 Aug)
Menashe I,Aloni R,Lancet D

DEFOG: a practical scheme for deciphering families of genes.
Genomics80(3)295-302(2002 Sep)
Fuchs T,Malecova B,Linhart C,Sharan R,Khen M,Herwig R,Shmulevich D,Elkon R,Steinfath M,O'Brien JK,Radelof U,Lehrach H,Lancet D,Shamir R

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.
Proceedings of the National Academy of Sciences of the United States of America97(26)14560-5(2000 Dec)
Bulger M,Bender MA,van Doorninck JH,Wertman B,Farrell CM,Felsenfeld G,Groudine M,Hardison R

Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.
Proceedings of the National Academy of Sciences of the United States of America96(9)5129-34(1999 Apr)
Bulger M,van Doorninck JH,Saitoh N,Telling A,Farrell C,Bender MA,Felsenfeld G,Axel R,Groudine M,von Doorninck JH

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OR51B2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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