TECTB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TECTB
Entrez Gene ID	6975
Full Name	tectorin beta
General protein information	Preferred Names tectorin beta Names beta-tectorin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q25.2
Summary	This gene encodes a non-collagenous glycoprotein component of the tectorial membrane, which covers the auditory hair cells in the cochlea of the inner ear. A similar protein in mouse functions in low-frequency hearing. [provided by RefSeq, Jul 2013].
Disorder MIM:	602653

mRNA and Protein(s)

mRNA	Protein	Name
NM_058222.3	NP_478129.1	beta-tectorin precursor
NM_058222.2	NP_478129.1	beta-tectorin precursor
XM_017016604.1	XP_016872093.1	beta-tectorin isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TECTB	NP_478129.1
Canis lupus familiaris (dog)	TECTB	XP_005637785.1
Rattus norvegicus (Norway rat)	Tectb	NP_001099670.1
Xenopus tropicalis (tropical clawed frog)	tectb	XP_004916483.1
Pan troglodytes (chimpanzee)	TECTB	XP_521604.2
Gallus gallus (chicken)	TECTB	NP_990694.1
Danio rerio (zebrafish)	tectb	NP_001008594.1
Mus musculus (house mouse)	Tectb	NP_033374.2
	TECTB	XP_001088216.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification of polymorphisms in ultraconserved elements associated with clinical outcomes in locally advanced colorectal adenocarcinoma.
Lin M, Eng C, Hawk ET, Huang M, Lin J, Gu J, Ellis LM, Wu X
Cancer118(24)6188-98(2012 Dec)

Loss of mammal-specific tectorial membrane component carcinoembryonic antigen cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies.
Kammerer R, R?ttiger L, Riesenberg R, Sch?uble C, Krupar R, Kamp A, Sunami K, Eisenried A, Hennenberg M, Grunert F, Bress A, Battaglia S, Schrewe H, Knipper M, Schneider MR, Zimmermann W
The Journal of biological chemistry287(26)21584-98(2012 Jun)

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vri?ze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A
American journal of human genetics78(1)78-88(2006 Jan)

The mouse tectorins. Modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system.
Legan PK, Rau A, Keen JN, Richardson GP
The Journal of biological chemistry272(13)8791-801(1997 Mar)

Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening.
Robertson NG, Khetarpal U, Guti?rrez-Espeleta GA, Bieber FR, Morton CC
Genomics23(1)42-50(1994 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Single nucleotide polymorphism in the ultraconserved elements of TECTB gene is associated with recurrence in colorectal adenocarcinoma.
Title: Identification of polymorphisms in ultraconserved elements associated with clinical outcomes in locally advanced colorectal adenocarcinoma.

CEACAM16 can probably form higher order structures with other tectorial membrane proteins such as alpha-tectorin and beta-tectorin and influences the physical properties of the tectorial membrane
Title: Loss of mammal-specific tectorial membrane component carcinoembryonic antigen cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Observational study of gene-disease association. (HuGE Navigator)
Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

The following TECTB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TECTB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12078	NM_058222.3 Latest version!	Homo sapiens tectorin beta (TECTB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu91626	XM_017016604.1 Latest version!	Homo sapiens tectorin beta (TECTB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu12078	NM_058222.2	Homo sapiens tectorin beta (TECTB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TECTB ( NM_058222.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_478129.1 Homo sapiens tectorin beta (TECTB), mRNA.

Price & Availability↑

CloneID	OHu12078
Clone ID Related Accession (Same CDS sequence)	NM_058222.3 , NM_058222.2
Accession Version	NM_058222.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-09
Organism	Homo sapiens(human)
Product	beta-tectorin precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL391986.12 and BC113499.1. On Nov 7, 2018 this sequence version replaced NM_058222.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.20874.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000646139.2/ ENSP00000494896.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGACGA AGGCCTTTGT CTTGTTGGCC ATCTTTGCAG AAGCCTCTGC AAAATCGTGT 
GCTCCAAATA AAGCAGATGT CATTCTTGTG TTTTGCTATC CCAAAACCAT CATCACCAAA 
ATCCCCGAGT GTCCCTATGG ATGGGAAGTT CATCAGCTGG CCCTCGGAGG GCTGTGTTAC 
AATGGGGTCC ACGAAGGAGG TTACTACCAA TTTGTGATCC CAGATTTATC ACCTAAAAAC 
AAGTCCTATT GTGGAACCCA GTCTGAGTAC AAGCCACCTA TCTATCACTT CTACAGTCAC 
ATCGTTTCCA ATGACACCAC AGTGATTGTA AAAAACCAGC CTGTCAACTA CTCCTTCTCC 
TGCACCTACC ACTCCACCTA CTTGGTGAAC CAGGCTGCCT TTGACCAGAG AGTGGCCACT 
GTTCACGTGA AGAACGGGAG CATGGGCACA TTTGAGAGCC AACTGTCTCT CAACTTCTAC 
ACTAATGCCA AGTTCTCCAT CAAGAAAGAA GCTCCCTTTG TCCTGGAGGC ATCCGAAATC 
GGTTCAGATC TGTTTGCAGG AGTGGAAGCC AAAGGGTTAA GCATTAGGTT TAAAGTGGTC 
TTGAACAGCT GTTGGGCCAC CCCCTCGGCT GACTTCATGT ATCCCTTGCA GTGGCAGCTG 
ATCAACAAGG GCTGCCCCAC GGATGAAACC GTCCTCGTGC ATGAGAATGG GAGAGATCAC 
AGGGCAACCT TCCAATTCAA TGCTTTCCGG TTCCAGAACA TCCCCAAACT CTCCAAGGTG 
TGGTTACACT GTGAGACGTT CATCTGCGAC AGTGAGAAAC TCTCCTGCCC AGTGACCTGC 
GATAAACGGA AGCGCCTCCT GCGAGACCAG ACCGGGGGAG TCCTGGTCGT GGAGCTCTCC 
CTGCGGAGCA GGGGATTTTC CAGTCTCTAT AGCTTCTCAG ATGTTCTCCA CCACCTCATC 
ATGATGTTGG GGATTTGTGC CGTGTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_478129.1
CDS	185..1174
Translation	MVTKAFVLLAIFAEASAKSCAPNKADVILVFCYPKTIITKIPECPYGWEVHQLALGGLCYNGVHEGGYYQFVIPDLSPKNKSYCGTQSEYKPPIYHFYSHIVSNDTTVIVKNQPVNYSFSCTYHSTYLVNQAAFDQRVATVHVKNGSMGTFESQLSLNFYTNAKFSIKKEAPFVLEASEIGSDLFAGVEAKGLSIRFKVVLNSCWATPSADFMYPLQWQLINKGCPTDETVLVHENGRDHRATFQFNAFRFQNIPKLSKVWLHCETFICDSEKLSCPVTCDKRKRLLRDQTGGVLVVELSLRSRGFSSLYSFSDVLHHLIMMLGICAVL

Target ORF information:

RefSeq Version	NM_058222.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tectorin beta (TECTB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_058222.3

ORF Insert Sequence:

ATGGTGACGA AGGCCTTTGT CTTGTTGGCC ATCTTTGCAG AAGCCTCTGC AAAATCGTGT 
GCTCCAAATA AAGCAGATGT CATTCTTGTG TTTTGCTATC CCAAAACCAT CATCACCAAA 
ATCCCCGAGT GTCCCTATGG ATGGGAAGTT CATCAGCTGG CCCTCGGAGG GCTGTGTTAC 
AATGGGGTCC ACGAAGGAGG TTACTACCAA TTTGTGATCC CAGATTTATC ACCTAAAAAC 
AAGTCCTATT GTGGAACCCA GTCTGAGTAC AAGCCACCTA TCTATCACTT CTACAGTCAC 
ATCGTTTCCA ATGACACCAC AGTGATTGTA AAAAACCAGC CTGTCAACTA CTCCTTCTCC 
TGCACCTACC ACTCCACCTA CTTGGTGAAC CAGGCTGCCT TTGACCAGAG AGTGGCCACT 
GTTCACGTGA AGAACGGGAG CATGGGCACA TTTGAGAGCC AACTGTCTCT CAACTTCTAC 
ACTAATGCCA AGTTCTCCAT CAAGAAAGAA GCTCCCTTTG TCCTGGAGGC ATCCGAAATC 
GGTTCAGATC TGTTTGCAGG AGTGGAAGCC AAAGGGTTAA GCATTAGGTT TAAAGTGGTC 
TTGAACAGCT GTTGGGCCAC CCCCTCGGCT GACTTCATGT ATCCCTTGCA GTGGCAGCTG 
ATCAACAAGG GCTGCCCCAC GGATGAAACC GTCCTCGTGC ATGAGAATGG GAGAGATCAC 
AGGGCAACCT TCCAATTCAA TGCTTTCCGG TTCCAGAACA TCCCCAAACT CTCCAAGGTG 
TGGTTACACT GTGAGACGTT CATCTGCGAC AGTGAGAAAC TCTCCTGCCC AGTGACCTGC 
GATAAACGGA AGCGCCTCCT GCGAGACCAG ACCGGGGGAG TCCTGGTCGT GGAGCTCTCC 
CTGCGGAGCA GGGGATTTTC CAGTCTCTAT AGCTTCTCAG ATGTTCTCCA CCACCTCATC 
ATGATGTTGG GGATTTGTGC CGTGTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TECTB ( NM_058222.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_478129.1 Homo sapiens tectorin beta (TECTB), mRNA.

Price & Availability↑

CloneID	OHu12078
Clone ID Related Accession (Same CDS sequence)	NM_058222.3 , NM_058222.2
Accession Version	NM_058222.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	beta-tectorin precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC113499.1, AL391986.12 and AW021518.1. On Jul 30, 2013 this sequence version replaced NM_058222.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC113497.1, AF312827.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA2144835 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGACGA AGGCCTTTGT CTTGTTGGCC ATCTTTGCAG AAGCCTCTGC AAAATCGTGT 
GCTCCAAATA AAGCAGATGT CATTCTTGTG TTTTGCTATC CCAAAACCAT CATCACCAAA 
ATCCCCGAGT GTCCCTATGG ATGGGAAGTT CATCAGCTGG CCCTCGGAGG GCTGTGTTAC 
AATGGGGTCC ACGAAGGAGG TTACTACCAA TTTGTGATCC CAGATTTATC ACCTAAAAAC 
AAGTCCTATT GTGGAACCCA GTCTGAGTAC AAGCCACCTA TCTATCACTT CTACAGTCAC 
ATCGTTTCCA ATGACACCAC AGTGATTGTA AAAAACCAGC CTGTCAACTA CTCCTTCTCC 
TGCACCTACC ACTCCACCTA CTTGGTGAAC CAGGCTGCCT TTGACCAGAG AGTGGCCACT 
GTTCACGTGA AGAACGGGAG CATGGGCACA TTTGAGAGCC AACTGTCTCT CAACTTCTAC 
ACTAATGCCA AGTTCTCCAT CAAGAAAGAA GCTCCCTTTG TCCTGGAGGC ATCCGAAATC 
GGTTCAGATC TGTTTGCAGG AGTGGAAGCC AAAGGGTTAA GCATTAGGTT TAAAGTGGTC 
TTGAACAGCT GTTGGGCCAC CCCCTCGGCT GACTTCATGT ATCCCTTGCA GTGGCAGCTG 
ATCAACAAGG GCTGCCCCAC GGATGAAACC GTCCTCGTGC ATGAGAATGG GAGAGATCAC 
AGGGCAACCT TCCAATTCAA TGCTTTCCGG TTCCAGAACA TCCCCAAACT CTCCAAGGTG 
TGGTTACACT GTGAGACGTT CATCTGCGAC AGTGAGAAAC TCTCCTGCCC AGTGACCTGC 
GATAAACGGA AGCGCCTCCT GCGAGACCAG ACCGGGGGAG TCCTGGTCGT GGAGCTCTCC 
CTGCGGAGCA GGGGATTTTC CAGTCTCTAT AGCTTCTCAG ATGTTCTCCA CCACCTCATC 
ATGATGTTGG GGATTTGTGC CGTGTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_478129.1
CDS	80..1069
Translation	MVTKAFVLLAIFAEASAKSCAPNKADVILVFCYPKTIITKIPECPYGWEVHQLALGGLCYNGVHEGGYYQFVIPDLSPKNKSYCGTQSEYKPPIYHFYSHIVSNDTTVIVKNQPVNYSFSCTYHSTYLVNQAAFDQRVATVHVKNGSMGTFESQLSLNFYTNAKFSIKKEAPFVLEASEIGSDLFAGVEAKGLSIRFKVVLNSCWATPSADFMYPLQWQLINKGCPTDETVLVHENGRDHRATFQFNAFRFQNIPKLSKVWLHCETFICDSEKLSCPVTCDKRKRLLRDQTGGVLVVELSLRSRGFSSLYSFSDVLHHLIMMLGICAVL

Target ORF information:

RefSeq Version	NM_058222.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tectorin beta (TECTB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_058222.2

ORF Insert Sequence:

ATGGTGACGA AGGCCTTTGT CTTGTTGGCC ATCTTTGCAG AAGCCTCTGC AAAATCGTGT 
GCTCCAAATA AAGCAGATGT CATTCTTGTG TTTTGCTATC CCAAAACCAT CATCACCAAA 
ATCCCCGAGT GTCCCTATGG ATGGGAAGTT CATCAGCTGG CCCTCGGAGG GCTGTGTTAC 
AATGGGGTCC ACGAAGGAGG TTACTACCAA TTTGTGATCC CAGATTTATC ACCTAAAAAC 
AAGTCCTATT GTGGAACCCA GTCTGAGTAC AAGCCACCTA TCTATCACTT CTACAGTCAC 
ATCGTTTCCA ATGACACCAC AGTGATTGTA AAAAACCAGC CTGTCAACTA CTCCTTCTCC 
TGCACCTACC ACTCCACCTA CTTGGTGAAC CAGGCTGCCT TTGACCAGAG AGTGGCCACT 
GTTCACGTGA AGAACGGGAG CATGGGCACA TTTGAGAGCC AACTGTCTCT CAACTTCTAC 
ACTAATGCCA AGTTCTCCAT CAAGAAAGAA GCTCCCTTTG TCCTGGAGGC ATCCGAAATC 
GGTTCAGATC TGTTTGCAGG AGTGGAAGCC AAAGGGTTAA GCATTAGGTT TAAAGTGGTC 
TTGAACAGCT GTTGGGCCAC CCCCTCGGCT GACTTCATGT ATCCCTTGCA GTGGCAGCTG 
ATCAACAAGG GCTGCCCCAC GGATGAAACC GTCCTCGTGC ATGAGAATGG GAGAGATCAC 
AGGGCAACCT TCCAATTCAA TGCTTTCCGG TTCCAGAACA TCCCCAAACT CTCCAAGGTG 
TGGTTACACT GTGAGACGTT CATCTGCGAC AGTGAGAAAC TCTCCTGCCC AGTGACCTGC 
GATAAACGGA AGCGCCTCCT GCGAGACCAG ACCGGGGGAG TCCTGGTCGT GGAGCTCTCC 
CTGCGGAGCA GGGGATTTTC CAGTCTCTAT AGCTTCTCAG ATGTTCTCCA CCACCTCATC 
ATGATGTTGG GGATTTGTGC CGTGTTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TECTB ( XM_017016604.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016872093.1 Homo sapiens tectorin beta (TECTB), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu91626
Clone ID Related Accession (Same CDS sequence)	XM_017016604.1
Accession Version	XM_017016604.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 987bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	beta-tectorin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGACGA AGGCCTTTGT CTTGTTGGCC ATCTTTGCAG AAGCCTCTGC AAAATCGTGT 
GCTCCAAATA AAGCAGATGT CATTCTTGTG TTTTGCTATC CCAAAACCAT CATCACCAAA 
ATCCCCGAGT GTCCCTATGG ATGGGAAGTT CATCAGCTGG CCCTCGGAGG GCTGTGTTAC 
AATGGGGTCC ACGAAGGAGG TTACTACCAA TTTGTGATCC CAGATTTATC ACCTAAAAAC 
AAGTCCTATT GTGGAACCCA GTCTGAGTAC AAGCCACCTA TCTATCACTT CTACAGTCAC 
ATCGTTTCCA ATGACACCAC AGTGATTGTA AAAAACCAGC CTGTCAACTA CTCCTTCTCC 
TGCACCTACC ACTCCACCTA CTTGGTGAAC CAGGCTGCCT TTGACCAGAG AGTGGCCACT 
GTTCACGTGA AGAACGGGAG CATGGGCACA TTTGAGAGCC AACTGTCTCT CAACTTCTAC 
ACTAATGCCA AGTTCTCCAT CAAGAAAGAA GCTCCCTTTG TCCTGGAGGC ATCCGAAATC 
GGTTCAGATC TGTTTGCAGG AGTGGAAGCC AAAGGGTTAA GCATTAGGTT TAAAGTGGTC 
TTGAACAGCT GTTGGGCCAC CCCCTCGGCT GACTTCATGT ATCCCTTGCA GTGGCAGCTG 
ATCAACAAGG GCTGCCCCAC GGATGAAACC GTCCTCGTGC ATGAGAATGG GAGAGATCAC 
AGGGCAACCT TCCAATTCAA TGCTTTCCGG TTCCAGAACA TCCCCAAACT CTCCAAGGTG 
TGGTTACACT GTGAGACGTT CATCTGCGAC AGTGAGAAAC TCTCCTGCCC AGTGACCTGC 
GATAAACGGA AGCGCCTCCT GCGAGACCAG ACCGGGGGAG TCCTGGTCGT GGAGCTCTCC 
CTGCGGAGCA GGGGATTTTC CAGTCTCTAT AGCTTCTCAG GTAAGGAAAA GAGACACTTC 
TGGGATTTCG TGGGGCTATG CTGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016872093.1
CDS	74..1060
Translation	MVTKAFVLLAIFAEASAKSCAPNKADVILVFCYPKTIITKIPECPYGWEVHQLALGGLCYNGVHEGGYYQFVIPDLSPKNKSYCGTQSEYKPPIYHFYSHIVSNDTTVIVKNQPVNYSFSCTYHSTYLVNQAAFDQRVATVHVKNGSMGTFESQLSLNFYTNAKFSIKKEAPFVLEASEIGSDLFAGVEAKGLSIRFKVVLNSCWATPSADFMYPLQWQLINKGCPTDETVLVHENGRDHRATFQFNAFRFQNIPKLSKVWLHCETFICDSEKLSCPVTCDKRKRLLRDQTGGVLVVELSLRSRGFSSLYSFSGKEKRHFWDFVGLCC

Target ORF information:

RefSeq Version	XM_017016604.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tectorin beta (TECTB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017016604.1

ORF Insert Sequence:

ATGGTGACGA AGGCCTTTGT CTTGTTGGCC ATCTTTGCAG AAGCCTCTGC AAAATCGTGT 
GCTCCAAATA AAGCAGATGT CATTCTTGTG TTTTGCTATC CCAAAACCAT CATCACCAAA 
ATCCCCGAGT GTCCCTATGG ATGGGAAGTT CATCAGCTGG CCCTCGGAGG GCTGTGTTAC 
AATGGGGTCC ACGAAGGAGG TTACTACCAA TTTGTGATCC CAGATTTATC ACCTAAAAAC 
AAGTCCTATT GTGGAACCCA GTCTGAGTAC AAGCCACCTA TCTATCACTT CTACAGTCAC 
ATCGTTTCCA ATGACACCAC AGTGATTGTA AAAAACCAGC CTGTCAACTA CTCCTTCTCC 
TGCACCTACC ACTCCACCTA CTTGGTGAAC CAGGCTGCCT TTGACCAGAG AGTGGCCACT 
GTTCACGTGA AGAACGGGAG CATGGGCACA TTTGAGAGCC AACTGTCTCT CAACTTCTAC 
ACTAATGCCA AGTTCTCCAT CAAGAAAGAA GCTCCCTTTG TCCTGGAGGC ATCCGAAATC 
GGTTCAGATC TGTTTGCAGG AGTGGAAGCC AAAGGGTTAA GCATTAGGTT TAAAGTGGTC 
TTGAACAGCT GTTGGGCCAC CCCCTCGGCT GACTTCATGT ATCCCTTGCA GTGGCAGCTG 
ATCAACAAGG GCTGCCCCAC GGATGAAACC GTCCTCGTGC ATGAGAATGG GAGAGATCAC 
AGGGCAACCT TCCAATTCAA TGCTTTCCGG TTCCAGAACA TCCCCAAACT CTCCAAGGTG 
TGGTTACACT GTGAGACGTT CATCTGCGAC AGTGAGAAAC TCTCCTGCCC AGTGACCTGC 
GATAAACGGA AGCGCCTCCT GCGAGACCAG ACCGGGGGAG TCCTGGTCGT GGAGCTCTCC 
CTGCGGAGCA GGGGATTTTC CAGTCTCTAT AGCTTCTCAG GTAAGGAAAA GAGACACTTC 
TGGGATTTCG TGGGGCTATG CTGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of polymorphisms in ultraconserved elements associated with clinical outcomes in locally advanced colorectal adenocarcinoma.
Cancer118(24)6188-98(2012 Dec)
Lin M,Eng C,Hawk ET,Huang M,Lin J,Gu J,Ellis LM,Wu X

Loss of mammal-specific tectorial membrane component carcinoembryonic antigen cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies.
The Journal of biological chemistry287(26)21584-98(2012 Jun)
Kammerer R,R?ttiger L,Riesenberg R,Sch?uble C,Krupar R,Kamp A,Sunami K,Eisenried A,Hennenberg M,Grunert F,Bress A,Battaglia S,Schrewe H,Knipper M,Schneider MR,Zimmermann W

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
American journal of human genetics78(1)78-88(2006 Jan)
Grupe A,Li Y,Rowland C,Nowotny P,Hinrichs AL,Smemo S,Kauwe JS,Maxwell TJ,Cherny S,Doil L,Tacey K,van Luchene R,Myers A,Wavrant-De Vri?ze F,Kaleem M,Hollingworth P,Jehu L,Foy C,Archer N,Hamilton G,Holmans P,Morris CM,Catanese J,Sninsky J,White TJ,Powell J,Hardy J,O'Donovan M,Lovestone S,Jones L,Morris JC,Thal L,Owen M,Williams J,Goate A

The mouse tectorins. Modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system.
The Journal of biological chemistry272(13)8791-801(1997 Mar)
Legan PK,Rau A,Keen JN,Richardson GP

Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening.
Genomics23(1)42-50(1994 Sep)
Robertson NG,Khetarpal U,Guti?rrez-Espeleta GA,Bieber FR,Morton CC