SH3GL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SH3GL1
Entrez Gene ID	6455
Full Name	SH3 domain containing GRB2 like 1, endophilin A2
Synonyms	CNSA1,EEN,SH3D2B,SH3P8
General protein information	Preferred Names SH3 domain containing GRB2 like 1, endophilin A2 Names endophilin-A2 EEN fusion partner of MLL SH3 domain protein 2B SH3 domain-containing GRB2-like protein 1 SH3-containing Grb-2-like 1 protein SH3-domain GRB2-like 1 endophilin-2 extra 11-19 leukemia fusion extra eleven-nineteen leukemia fusion gene protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.3
Summary	This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].
Disorder MIM:	601768
Disorder Html:	Leukemia, acute myeloid, 601626 (1)

mRNA and Protein(s)

mRNA	Protein	Name
NM_003025.3	NP_003016.1	endophilin-A2 isoform 1
NM_001199943.2	NP_001186872.1	endophilin-A2 isoform 2
NM_001199944.2	NP_001186873.1	endophilin-A2 isoform 3
XM_011528183.2	XP_011526485.1	endophilin-A2 isoform X2
NM_001199943.1	NP_001186872.1	endophilin-A2 isoform 2
XM_017027146.1	XP_016882635.1	endophilin-A2 isoform X1
NM_003025.4	NP_003016.1	endophilin-A2 isoform 1
NM_001199944.1	NP_001186873.1	endophilin-A2 isoform 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	SH3GL1	NP_003016.1
Mus musculus (house mouse)	Sh3gl1	NP_038692.1
Rattus norvegicus (Norway rat)	Sh3gl1	NP_112518.1
Gallus gallus (chicken)	SH3GL1	NP_989860.1
Danio rerio (zebrafish)	sh3gl1b	NP_958905.1
Pan troglodytes (chimpanzee)	SH3GL1	XP_001138821.2
	SH3GL1	XP_001101957.2
Canis lupus familiaris (dog)	SH3GL1	XP_854499.1
Xenopus tropicalis (tropical clawed frog)	sh3gl1	NP_989126.1
Bos taurus (cattle)	SH3GL1	NP_001039595.1

Gene Ontology
Bibliography

Related articles in PubMed

Endophilin A2: A Potential Link to Adiposity and Beyond.
Alfadda AA, Sallam RM, Gul R, Hwang I, Ka S
Molecules and cells40(11)855-863(2017 Nov)

Endophilin A2 promotes HER2 internalization and sensitivity to trastuzumab-based therapy in HER2-positive breast cancers.
Baldassarre T, Truesdell P, Craig AW
Breast cancer research : BCR19(1)110(2017 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Endophilin-A2 was identified as a novel molecule regulating macrophage-derived foam cell formation by mechanisms attributable to clathrin-mediated endocytosis and beyond clathrin-mediated endocytosis
Title: Endophilin-A2-mediated increase in scavenger receptor expression contributes to macrophage-derived foam cell formation.

inhibition of SH3GL1 reverses multidrug resistance through declining P-glycoprotein expression via the EGFR/ERK/AP-1 pathway.
Title: SH3GL1 inhibition reverses multidrug resistance in colorectal cancer cells by downregulation of MDR1/P-glycoprotein via EGFR/ERK/AP-1 pathway.

Endo II expression was highest in triple-negative breast cancers tumors compared with other subtypes, and at the level of gene expression, high Endo II was associated with reduced relapse-free survival in patients with basal-like breast cancers.
Title: Endophilin A2 Promotes TNBC Cell Invasion and Tumor Metastasis.

results establish a novel function of endoA2 in clathrin-independent endocytosis
Title: Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis.

these data suggest that EEN may play a pivotal role in excessive cell proliferation and insufficient cell apoptosis of bone marrow plasma cells in multiple myeloma.
Title: EEN regulates the proliferation and survival of multiple myeloma cells by potentiating IGF-1 secretion.

The following SH3GL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SH3GL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22717	NM_003025.4 Latest version!	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu13823	NM_001199943.2 Latest version!	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu15108	NM_001199944.2 Latest version!	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu60477	XM_011528183.2 Latest version!	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu88670	XM_017027146.1 Latest version!	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu13823	NM_001199943.1	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu22717	NM_003025.3	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu15108	NM_001199944.1	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SH3GL1 ( NM_003025.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003016.1 Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu22717
Clone ID Related Accession (Same CDS sequence)	NM_003025.3 , NM_003025.4
Accession Version	NM_003025.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1107bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	endophilin-A2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU838380.1, BC001270.1 and AC007292.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_003025.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC098565.1, SRR1163657.444973.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000269886.7/ ENSP00000269886.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGCCT CGCGGGCTAA GCTGACCATG CTCAACACGG TGTCCAAGAT CCGGGGCCAG 
GTGAAGAACC CCGGCTACCC GCAGTCGGAG GGGCTTCTGG GCGAGTGCAT GATCCGCCAC 
GGGAAGGAGC TGGGCGGCGA GTCCAACTTT GGTGACGCAT TGCTGGATGC CGGCGAGTCC 
ATGAAGCGCC TGGCAGAGGT GAAGGACTCC CTGGACATCG AGGTCAAGCA GAACTTCATT 
GACCCCCTCC AGAACCTGTG CGAGAAAGAC CTGAAGGAGA TCCAGCACCA CCTGAAGAAA 
CTGGAGGGCC GCCGCCTGGA CTTTGACTAC AAGAAGAAGC GGCAGGGCAA GATCCCCGAT 
GAGGAGCTAC GCCAGGCGCT GGAGAAGTTC GAGGAGTCCA AGGAGGTGGC AGAAACCAGC 
ATGCACAACC TCCTGGAGAC TGACATCGAG CAGGTGAGTC AGCTCTCGGC CCTGGTGGAT 
GCACAGCTGG ACTACCACCG GCAGGCCGTG CAGATCCTGG ACGAGCTGGC GGAGAAGCTC 
AAGCGCAGGA TGCGGGAAGC TTCCTCACGC CCTAAGCGGG AGTATAAGCC CAAGCCCCGG 
GAGCCCTTTG ACCTTGGAGA GCCTGAGCAG TCCAACGGGG GCTTCCCCTG CACCACAGCC 
CCCAAGATCG CAGCTTCATC GTCTTTCCGA TCTTCCGACA AGCCCATCCG GACCCCTAGC 
CGGAGCATGC CGCCCCTGGA CCAGCCGAGC TGCAAGGCGC TGTACGACTT CGAGCCCGAG 
AACGACGGGG AGCTGGGCTT CCATGAGGGC GACGTCATCA CGCTGACCAA CCAGATCGAT 
GAGAACTGGT ACGAGGGCAT GCTGGACGGC CAGTCGGGCT TCTTCCCGCT CAGCTACGTG 
GAGGTGCTTG TGCCCCTGCC GCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003016.1
CDS	180..1286
Translation	MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVEVLVPLPQ

Target ORF information:

RefSeq Version	NM_003025.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003025.4

ORF Insert Sequence:

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGCCT CGCGGGCTAA GCTGACCATG CTCAACACGG TGTCCAAGAT CCGGGGCCAG 
GTGAAGAACC CCGGCTACCC GCAGTCGGAG GGGCTTCTGG GCGAGTGCAT GATCCGCCAC 
GGGAAGGAGC TGGGCGGCGA GTCCAACTTT GGTGACGCAT TGCTGGATGC CGGCGAGTCC 
ATGAAGCGCC TGGCAGAGGT GAAGGACTCC CTGGACATCG AGGTCAAGCA GAACTTCATT 
GACCCCCTCC AGAACCTGTG CGAGAAAGAC CTGAAGGAGA TCCAGCACCA CCTGAAGAAA 
CTGGAGGGCC GCCGCCTGGA CTTTGACTAC AAGAAGAAGC GGCAGGGCAA GATCCCCGAT 
GAGGAGCTAC GCCAGGCGCT GGAGAAGTTC GAGGAGTCCA AGGAGGTGGC AGAAACCAGC 
ATGCACAACC TCCTGGAGAC TGACATCGAG CAGGTGAGTC AGCTCTCGGC CCTGGTGGAT 
GCACAGCTGG ACTACCACCG GCAGGCCGTG CAGATCCTGG ACGAGCTGGC GGAGAAGCTC 
AAGCGCAGGA TGCGGGAAGC TTCCTCACGC CCTAAGCGGG AGTATAAGCC CAAGCCCCGG 
GAGCCCTTTG ACCTTGGAGA GCCTGAGCAG TCCAACGGGG GCTTCCCCTG CACCACAGCC 
CCCAAGATCG CAGCTTCATC GTCTTTCCGA TCTTCCGACA AGCCCATCCG GACCCCTAGC 
CGGAGCATGC CGCCCCTGGA CCAGCCGAGC TGCAAGGCGC TGTACGACTT CGAGCCCGAG 
AACGACGGGG AGCTGGGCTT CCATGAGGGC GACGTCATCA CGCTGACCAA CCAGATCGAT 
GAGAACTGGT ACGAGGGCAT GCTGGACGGC CAGTCGGGCT TCTTCCCGCT CAGCTACGTG 
GAGGTGCTTG TGCCCCTGCC GCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3GL1 ( NM_001199943.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186872.1 Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13823
Clone ID Related Accession (Same CDS sequence)	NM_001199943.2 , NM_001199943.1
Accession Version	NM_001199943.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 963bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	endophilin-A2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU838380.1, AK299166.1, X99656.1 and CK820395.1. On May 31, 2019 this sequence version replaced NM_001199943.1. Transcript Variant: This variant (2) lacks an exon in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK299166.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGGTG ACGCATTGCT GGATGCCGGC GAGTCCATGA AGCGCCTGGC AGAGGTGAAG 
GACTCCCTGG ACATCGAGGT CAAGCAGAAC TTCATTGACC CCCTCCAGAA CCTGTGCGAG 
AAAGACCTGA AGGAGATCCA GCACCACCTG AAGAAACTGG AGGGCCGCCG CCTGGACTTT 
GACTACAAGA AGAAGCGGCA GGGCAAGATC CCCGATGAGG AGCTACGCCA GGCGCTGGAG 
AAGTTCGAGG AGTCCAAGGA GGTGGCAGAA ACCAGCATGC ACAACCTCCT GGAGACTGAC 
ATCGAGCAGG TGAGTCAGCT CTCGGCCCTG GTGGATGCAC AGCTGGACTA CCACCGGCAG 
GCCGTGCAGA TCCTGGACGA GCTGGCGGAG AAGCTCAAGC GCAGGATGCG GGAAGCTTCC 
TCACGCCCTA AGCGGGAGTA TAAGCCCAAG CCCCGGGAGC CCTTTGACCT TGGAGAGCCT 
GAGCAGTCCA ACGGGGGCTT CCCCTGCACC ACAGCCCCCA AGATCGCAGC TTCATCGTCT 
TTCCGATCTT CCGACAAGCC CATCCGGACC CCTAGCCGGA GCATGCCGCC CCTGGACCAG 
CCGAGCTGCA AGGCGCTGTA CGACTTCGAG CCCGAGAACG ACGGGGAGCT GGGCTTCCAT 
GAGGGCGACG TCATCACGCT GACCAACCAG ATCGATGAGA ACTGGTACGA GGGCATGCTG 
GACGGCCAGT CGGGCTTCTT CCCGCTCAGC TACGTGGAGG TGCTTGTGCC CCTGCCGCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186872.1
CDS	180..1142
Translation	MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQPNPGDALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVEVLVPLPQ

Target ORF information:

RefSeq Version	NM_001199943.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199943.2

ORF Insert Sequence:

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGGTG ACGCATTGCT GGATGCCGGC GAGTCCATGA AGCGCCTGGC AGAGGTGAAG 
GACTCCCTGG ACATCGAGGT CAAGCAGAAC TTCATTGACC CCCTCCAGAA CCTGTGCGAG 
AAAGACCTGA AGGAGATCCA GCACCACCTG AAGAAACTGG AGGGCCGCCG CCTGGACTTT 
GACTACAAGA AGAAGCGGCA GGGCAAGATC CCCGATGAGG AGCTACGCCA GGCGCTGGAG 
AAGTTCGAGG AGTCCAAGGA GGTGGCAGAA ACCAGCATGC ACAACCTCCT GGAGACTGAC 
ATCGAGCAGG TGAGTCAGCT CTCGGCCCTG GTGGATGCAC AGCTGGACTA CCACCGGCAG 
GCCGTGCAGA TCCTGGACGA GCTGGCGGAG AAGCTCAAGC GCAGGATGCG GGAAGCTTCC 
TCACGCCCTA AGCGGGAGTA TAAGCCCAAG CCCCGGGAGC CCTTTGACCT TGGAGAGCCT 
GAGCAGTCCA ACGGGGGCTT CCCCTGCACC ACAGCCCCCA AGATCGCAGC TTCATCGTCT 
TTCCGATCTT CCGACAAGCC CATCCGGACC CCTAGCCGGA GCATGCCGCC CCTGGACCAG 
CCGAGCTGCA AGGCGCTGTA CGACTTCGAG CCCGAGAACG ACGGGGAGCT GGGCTTCCAT 
GAGGGCGACG TCATCACGCT GACCAACCAG ATCGATGAGA ACTGGTACGA GGGCATGCTG 
GACGGCCAGT CGGGCTTCTT CCCGCTCAGC TACGTGGAGG TGCTTGTGCC CCTGCCGCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3GL1 ( NM_001199943.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186872.1 Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13823
Clone ID Related Accession (Same CDS sequence)	NM_001199943.2 , NM_001199943.1
Accession Version	NM_001199943.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 963bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-07-14
Organism	Homo sapiens(human)
Product	endophilin-A2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU838380.1, AK299166.1, X99656.1 and CK820395.1. Transcript Variant: This variant (2) lacks an exon in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK299166.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGGTG ACGCATTGCT GGATGCCGGC GAGTCCATGA AGCGCCTGGC AGAGGTGAAG 
GACTCCCTGG ACATCGAGGT CAAGCAGAAC TTCATTGACC CCCTCCAGAA CCTGTGCGAG 
AAAGACCTGA AGGAGATCCA GCACCACCTG AAGAAACTGG AGGGCCGCCG CCTGGACTTT 
GACTACAAGA AGAAGCGGCA GGGCAAGATC CCCGATGAGG AGCTACGCCA GGCGCTGGAG 
AAGTTCGAGG AGTCCAAGGA GGTGGCAGAA ACCAGCATGC ACAACCTCCT GGAGACTGAC 
ATCGAGCAGG TGAGTCAGCT CTCGGCCCTG GTGGATGCAC AGCTGGACTA CCACCGGCAG 
GCCGTGCAGA TCCTGGACGA GCTGGCGGAG AAGCTCAAGC GCAGGATGCG GGAAGCTTCC 
TCACGCCCTA AGCGGGAGTA TAAGCCCAAG CCCCGGGAGC CCTTTGACCT TGGAGAGCCT 
GAGCAGTCCA ACGGGGGCTT CCCCTGCACC ACAGCCCCCA AGATCGCAGC TTCATCGTCT 
TTCCGATCTT CCGACAAGCC CATCCGGACC CCTAGCCGGA GCATGCCGCC CCTGGACCAG 
CCGAGCTGCA AGGCGCTGTA CGACTTCGAG CCCGAGAACG ACGGGGAGCT GGGCTTCCAT 
GAGGGCGACG TCATCACGCT GACCAACCAG ATCGATGAGA ACTGGTACGA GGGCATGCTG 
GACGGCCAGT CGGGCTTCTT CCCGCTCAGC TACGTGGAGG TGCTTGTGCC CCTGCCGCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186872.1
CDS	201..1163
Translation	MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQPNPGDALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVEVLVPLPQ

Target ORF information:

RefSeq Version	NM_001199943.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199943.1

ORF Insert Sequence:

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGGTG ACGCATTGCT GGATGCCGGC GAGTCCATGA AGCGCCTGGC AGAGGTGAAG 
GACTCCCTGG ACATCGAGGT CAAGCAGAAC TTCATTGACC CCCTCCAGAA CCTGTGCGAG 
AAAGACCTGA AGGAGATCCA GCACCACCTG AAGAAACTGG AGGGCCGCCG CCTGGACTTT 
GACTACAAGA AGAAGCGGCA GGGCAAGATC CCCGATGAGG AGCTACGCCA GGCGCTGGAG 
AAGTTCGAGG AGTCCAAGGA GGTGGCAGAA ACCAGCATGC ACAACCTCCT GGAGACTGAC 
ATCGAGCAGG TGAGTCAGCT CTCGGCCCTG GTGGATGCAC AGCTGGACTA CCACCGGCAG 
GCCGTGCAGA TCCTGGACGA GCTGGCGGAG AAGCTCAAGC GCAGGATGCG GGAAGCTTCC 
TCACGCCCTA AGCGGGAGTA TAAGCCCAAG CCCCGGGAGC CCTTTGACCT TGGAGAGCCT 
GAGCAGTCCA ACGGGGGCTT CCCCTGCACC ACAGCCCCCA AGATCGCAGC TTCATCGTCT 
TTCCGATCTT CCGACAAGCC CATCCGGACC CCTAGCCGGA GCATGCCGCC CCTGGACCAG 
CCGAGCTGCA AGGCGCTGTA CGACTTCGAG CCCGAGAACG ACGGGGAGCT GGGCTTCCAT 
GAGGGCGACG TCATCACGCT GACCAACCAG ATCGATGAGA ACTGGTACGA GGGCATGCTG 
GACGGCCAGT CGGGCTTCTT CCCGCTCAGC TACGTGGAGG TGCTTGTGCC CCTGCCGCAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3GL1 ( NM_001199944.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186873.1 Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu15108
Clone ID Related Accession (Same CDS sequence)	NM_001199944.2 , NM_001199944.1
Accession Version	NM_001199944.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 915bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	endophilin-A2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC011498.7, AK097616.1, AC007292.1 and CK820395.1. On May 31, 2019 this sequence version replaced NM_001199944.1. Transcript Variant: This variant (3) uses two alternate in-frame splice sites in the coding region but maintains the reading frame, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK097616.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGCCT CGCGGGCTAA GCTGACCATG CTCAACACGG TGTCCAAGAT CCGGGGCCAG 
AACCTGTGCG AGAAAGACCT GAAGGAGATC CAGCACCACC TGAAGAAACT GGAGGGCCGC 
CGCCTGGACT TTGACTACAA GAAGAAGCGG CAGGGCAAGA TCCCCGATGA GGAGCTACGC 
CAGGCGCTGG AGAAGTTCGA GGAGTCCAAG GAGGTGGCAG AAACCAGCAT GCACAACCTC 
CTGGAGACTG ACATCGAGCA GGTGAGTCAG CTCTCGGCCC TGGTGGATGC ACAGCTGGAC 
TACCACCGGC AGGCCGTGCA GATCCTGGAC GAGCTGGCGG AGAAGCTCAA GCGCAGGATG 
CGGGAAGCTT CCTCACGCCC TAAGCGGGAG TATAAGCCCA AGCCCCGGGA GCCCTTTGAC 
CTTGGAGAGC CTGAGCAGTC CAACGGGGGC TTCCCCTGCA CCACAGCCCC CAAGATCGCA 
GCTTCATCGT CTTTCCGATC TTCCGACAAG CCCATCCGGA CCCCTAGCCG GAGCATGCCG 
CCCCTGGACC AGCCGAGCTG CAAGGCGCTG TACGACTTCG AGCCCGAGAA CGACGGGGAG 
CTGGGCTTCC ATGAGGGCGA CGTCATCACG CTGACCAACC AGATCGATGA GAACTGGTAC 
GAGGGCATGC TGGACGGCCA GTCGGGCTTC TTCCCGCTCA GCTACGTGGA GGTGCTTGTG 
CCCCTGCCGC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186873.1
CDS	180..1094
Translation	MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQPNPASRAKLTMLNTVSKIRGQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVEVLVPLPQ

Target ORF information:

RefSeq Version	NM_001199944.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199944.2

ORF Insert Sequence:

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGCCT CGCGGGCTAA GCTGACCATG CTCAACACGG TGTCCAAGAT CCGGGGCCAG 
AACCTGTGCG AGAAAGACCT GAAGGAGATC CAGCACCACC TGAAGAAACT GGAGGGCCGC 
CGCCTGGACT TTGACTACAA GAAGAAGCGG CAGGGCAAGA TCCCCGATGA GGAGCTACGC 
CAGGCGCTGG AGAAGTTCGA GGAGTCCAAG GAGGTGGCAG AAACCAGCAT GCACAACCTC 
CTGGAGACTG ACATCGAGCA GGTGAGTCAG CTCTCGGCCC TGGTGGATGC ACAGCTGGAC 
TACCACCGGC AGGCCGTGCA GATCCTGGAC GAGCTGGCGG AGAAGCTCAA GCGCAGGATG 
CGGGAAGCTT CCTCACGCCC TAAGCGGGAG TATAAGCCCA AGCCCCGGGA GCCCTTTGAC 
CTTGGAGAGC CTGAGCAGTC CAACGGGGGC TTCCCCTGCA CCACAGCCCC CAAGATCGCA 
GCTTCATCGT CTTTCCGATC TTCCGACAAG CCCATCCGGA CCCCTAGCCG GAGCATGCCG 
CCCCTGGACC AGCCGAGCTG CAAGGCGCTG TACGACTTCG AGCCCGAGAA CGACGGGGAG 
CTGGGCTTCC ATGAGGGCGA CGTCATCACG CTGACCAACC AGATCGATGA GAACTGGTAC 
GAGGGCATGC TGGACGGCCA GTCGGGCTTC TTCCCGCTCA GCTACGTGGA GGTGCTTGTG 
CCCCTGCCGC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3GL1 ( NM_001199944.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001186873.1 Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu15108
Clone ID Related Accession (Same CDS sequence)	NM_001199944.2 , NM_001199944.1
Accession Version	NM_001199944.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 915bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-07-14
Organism	Homo sapiens(human)
Product	endophilin-A2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK097616.1, AC007292.1 and CK820395.1. Transcript Variant: This variant (3) uses two alternate in-frame splice sites in the coding region but maintains the reading frame, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK097616.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGCCT CGCGGGCTAA GCTGACCATG CTCAACACGG TGTCCAAGAT CCGGGGCCAG 
AACCTGTGCG AGAAAGACCT GAAGGAGATC CAGCACCACC TGAAGAAACT GGAGGGCCGC 
CGCCTGGACT TTGACTACAA GAAGAAGCGG CAGGGCAAGA TCCCCGATGA GGAGCTACGC 
CAGGCGCTGG AGAAGTTCGA GGAGTCCAAG GAGGTGGCAG AAACCAGCAT GCACAACCTC 
CTGGAGACTG ACATCGAGCA GGTGAGTCAG CTCTCGGCCC TGGTGGATGC ACAGCTGGAC 
TACCACCGGC AGGCCGTGCA GATCCTGGAC GAGCTGGCGG AGAAGCTCAA GCGCAGGATG 
CGGGAAGCTT CCTCACGCCC TAAGCGGGAG TATAAGCCCA AGCCCCGGGA GCCCTTTGAC 
CTTGGAGAGC CTGAGCAGTC CAACGGGGGC TTCCCCTGCA CCACAGCCCC CAAGATCGCA 
GCTTCATCGT CTTTCCGATC TTCCGACAAG CCCATCCGGA CCCCTAGCCG GAGCATGCCG 
CCCCTGGACC AGCCGAGCTG CAAGGCGCTG TACGACTTCG AGCCCGAGAA CGACGGGGAG 
CTGGGCTTCC ATGAGGGCGA CGTCATCACG CTGACCAACC AGATCGATGA GAACTGGTAC 
GAGGGCATGC TGGACGGCCA GTCGGGCTTC TTCCCGCTCA GCTACGTGGA GGTGCTTGTG 
CCCCTGCCGC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001186873.1
CDS	51..965
Translation	MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQPNPASRAKLTMLNTVSKIRGQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVEVLVPLPQ

Target ORF information:

RefSeq Version	NM_001199944.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001199944.1

ORF Insert Sequence:

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGCCT CGCGGGCTAA GCTGACCATG CTCAACACGG TGTCCAAGAT CCGGGGCCAG 
AACCTGTGCG AGAAAGACCT GAAGGAGATC CAGCACCACC TGAAGAAACT GGAGGGCCGC 
CGCCTGGACT TTGACTACAA GAAGAAGCGG CAGGGCAAGA TCCCCGATGA GGAGCTACGC 
CAGGCGCTGG AGAAGTTCGA GGAGTCCAAG GAGGTGGCAG AAACCAGCAT GCACAACCTC 
CTGGAGACTG ACATCGAGCA GGTGAGTCAG CTCTCGGCCC TGGTGGATGC ACAGCTGGAC 
TACCACCGGC AGGCCGTGCA GATCCTGGAC GAGCTGGCGG AGAAGCTCAA GCGCAGGATG 
CGGGAAGCTT CCTCACGCCC TAAGCGGGAG TATAAGCCCA AGCCCCGGGA GCCCTTTGAC 
CTTGGAGAGC CTGAGCAGTC CAACGGGGGC TTCCCCTGCA CCACAGCCCC CAAGATCGCA 
GCTTCATCGT CTTTCCGATC TTCCGACAAG CCCATCCGGA CCCCTAGCCG GAGCATGCCG 
CCCCTGGACC AGCCGAGCTG CAAGGCGCTG TACGACTTCG AGCCCGAGAA CGACGGGGAG 
CTGGGCTTCC ATGAGGGCGA CGTCATCACG CTGACCAACC AGATCGATGA GAACTGGTAC 
GAGGGCATGC TGGACGGCCA GTCGGGCTTC TTCCCGCTCA GCTACGTGGA GGTGCTTGTG 
CCCCTGCCGC AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3GL1 ( NM_003025.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003016.1 Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 1, mRNA.

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CloneID	OHu22717
Clone ID Related Accession (Same CDS sequence)	NM_003025.3 , NM_003025.4
Accession Version	NM_003025.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1107bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	endophilin-A2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU838380.1, BC001270.1, AC007292.1 and CK820395.1. This sequence is a reference standard in the RefSeqGene project. On Jan 7, 2011 this sequence version replaced NM_003025.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC098565.1, SRR1163657.444973.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGCCT CGCGGGCTAA GCTGACCATG CTCAACACGG TGTCCAAGAT CCGGGGCCAG 
GTGAAGAACC CCGGCTACCC GCAGTCGGAG GGGCTTCTGG GCGAGTGCAT GATCCGCCAC 
GGGAAGGAGC TGGGCGGCGA GTCCAACTTT GGTGACGCAT TGCTGGATGC CGGCGAGTCC 
ATGAAGCGCC TGGCAGAGGT GAAGGACTCC CTGGACATCG AGGTCAAGCA GAACTTCATT 
GACCCCCTCC AGAACCTGTG CGAGAAAGAC CTGAAGGAGA TCCAGCACCA CCTGAAGAAA 
CTGGAGGGCC GCCGCCTGGA CTTTGACTAC AAGAAGAAGC GGCAGGGCAA GATCCCCGAT 
GAGGAGCTAC GCCAGGCGCT GGAGAAGTTC GAGGAGTCCA AGGAGGTGGC AGAAACCAGC 
ATGCACAACC TCCTGGAGAC TGACATCGAG CAGGTGAGTC AGCTCTCGGC CCTGGTGGAT 
GCACAGCTGG ACTACCACCG GCAGGCCGTG CAGATCCTGG ACGAGCTGGC GGAGAAGCTC 
AAGCGCAGGA TGCGGGAAGC TTCCTCACGC CCTAAGCGGG AGTATAAGCC CAAGCCCCGG 
GAGCCCTTTG ACCTTGGAGA GCCTGAGCAG TCCAACGGGG GCTTCCCCTG CACCACAGCC 
CCCAAGATCG CAGCTTCATC GTCTTTCCGA TCTTCCGACA AGCCCATCCG GACCCCTAGC 
CGGAGCATGC CGCCCCTGGA CCAGCCGAGC TGCAAGGCGC TGTACGACTT CGAGCCCGAG 
AACGACGGGG AGCTGGGCTT CCATGAGGGC GACGTCATCA CGCTGACCAA CCAGATCGAT 
GAGAACTGGT ACGAGGGCAT GCTGGACGGC CAGTCGGGCT TCTTCCCGCT CAGCTACGTG 
GAGGTGCTTG TGCCCCTGCC GCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003016.1
CDS	201..1307
Translation	MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVEVLVPLPQ

Target ORF information:

RefSeq Version	NM_003025.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003025.3

ORF Insert Sequence:

ATGTCGGTGG CGGGGCTGAA GAAGCAGTTC TACAAGGCGA GCCAGCTGGT CAGTGAGAAG 
GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT GATGACTTCA AAGAGATGGA GAAGAAGGTG 
GATGTCACCA GCAAGGCGGT GACAGAAGTG CTGGCCAGGA CCATCGAGTA CCTGCAGCCC 
AACCCAGCCT CGCGGGCTAA GCTGACCATG CTCAACACGG TGTCCAAGAT CCGGGGCCAG 
GTGAAGAACC CCGGCTACCC GCAGTCGGAG GGGCTTCTGG GCGAGTGCAT GATCCGCCAC 
GGGAAGGAGC TGGGCGGCGA GTCCAACTTT GGTGACGCAT TGCTGGATGC CGGCGAGTCC 
ATGAAGCGCC TGGCAGAGGT GAAGGACTCC CTGGACATCG AGGTCAAGCA GAACTTCATT 
GACCCCCTCC AGAACCTGTG CGAGAAAGAC CTGAAGGAGA TCCAGCACCA CCTGAAGAAA 
CTGGAGGGCC GCCGCCTGGA CTTTGACTAC AAGAAGAAGC GGCAGGGCAA GATCCCCGAT 
GAGGAGCTAC GCCAGGCGCT GGAGAAGTTC GAGGAGTCCA AGGAGGTGGC AGAAACCAGC 
ATGCACAACC TCCTGGAGAC TGACATCGAG CAGGTGAGTC AGCTCTCGGC CCTGGTGGAT 
GCACAGCTGG ACTACCACCG GCAGGCCGTG CAGATCCTGG ACGAGCTGGC GGAGAAGCTC 
AAGCGCAGGA TGCGGGAAGC TTCCTCACGC CCTAAGCGGG AGTATAAGCC CAAGCCCCGG 
GAGCCCTTTG ACCTTGGAGA GCCTGAGCAG TCCAACGGGG GCTTCCCCTG CACCACAGCC 
CCCAAGATCG CAGCTTCATC GTCTTTCCGA TCTTCCGACA AGCCCATCCG GACCCCTAGC 
CGGAGCATGC CGCCCCTGGA CCAGCCGAGC TGCAAGGCGC TGTACGACTT CGAGCCCGAG 
AACGACGGGG AGCTGGGCTT CCATGAGGGC GACGTCATCA CGCTGACCAA CCAGATCGAT 
GAGAACTGGT ACGAGGGCAT GCTGGACGGC CAGTCGGGCT TCTTCCCGCT CAGCTACGTG 
GAGGTGCTTG TGCCCCTGCC GCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3GL1 ( XM_011528183.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011526485.1 Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu60477
Clone ID Related Accession (Same CDS sequence)	XM_011528183.2
Accession Version	XM_011528183.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	endophilin-A2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011528183.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGA AGGTGGATGT CACCAGCAAG GCGGTGACAG AAGTGCTGGC CAGGACCATC 
GAGTACCTGC AGCCCAACCC AGCCTCGCGG GCTAAGCTGA CCATGCTCAA CACGGTGTCC 
AAGATCCGGG GCCAGGTGAA GAACCCCGGC TACCCGCAGT CGGAGGGGCT TCTGGGCGAG 
TGCATGATCC GCCACGGGAA GGAGCTGGGC GGCGAGTCCA ACTTTGGTGA CGCATTGCTG 
GATGCCGGCG AGTCCATGAA GCGCCTGGCA GAGGTGAAGG ACTCCCTGGA CATCGAGGTC 
AAGCAGAACT TCATTGACCC CCTCCAGAAC CTGTGCGAGA AAGACCTGAA GGAGATCCAG 
CACCACCTGA AGAAACTGGA GGGCCGCCGC CTGGACTTTG ACTACAAGAA GAAGCGGCAG 
GGCAAGATCC CCGATGAGGA GCTACGCCAG GCGCTGGAGA AGTTCGAGGA GTCCAAGGAG 
GTGGCAGAAA CCAGCATGCA CAACCTCCTG GAGACTGACA TCGAGCAGGT GAGTCAGCTC 
TCGGCCCTGG TGGATGCACA GCTGGACTAC CACCGGCAGG CCGTGCAGAT CCTGGACGAG 
CTGGCGGAGA AGCTCAAGCG CAGGATGCGG GAAGCTTCCT CACGCCCTAA GCGGGAGTAT 
AAGCCCAAGC CCCGGGAGCC CTTTGACCTT GGAGAGCCTG AGCAGTCCAA CGGGGGCTTC 
CCCTGCACCA CAGCCCCCAA GATCGCAGCT TCATCGTCTT TCCGATCTTC CGACAAGCCC 
ATCCGGACCC CTAGCCGGAG CATGCCGCCC CTGGACCAGC CGAGCTGCAA GGCGCTGTAC 
GACTTCGAGC CCGAGAACGA CGGGGAGCTG GGCTTCCATG AGGGCGACGT CATCACGCTG 
ACCAACCAGA TCGATGAGAA CTGGTACGAG GGCATGCTGG ACGGCCAGTC GGGCTTCTTC 
CCGCTCAGCT ACGTGGAGGT GCTTGTGCCC CTGCCGCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011526485.1
CDS	148..1149
Translation	MEKKVDVTSKAVTEVLARTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVEVLVPLPQ

Target ORF information:

RefSeq Version	XM_011528183.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011528183.2

ORF Insert Sequence:

ATGGAGAAGA AGGTGGATGT CACCAGCAAG GCGGTGACAG AAGTGCTGGC CAGGACCATC 
GAGTACCTGC AGCCCAACCC AGCCTCGCGG GCTAAGCTGA CCATGCTCAA CACGGTGTCC 
AAGATCCGGG GCCAGGTGAA GAACCCCGGC TACCCGCAGT CGGAGGGGCT TCTGGGCGAG 
TGCATGATCC GCCACGGGAA GGAGCTGGGC GGCGAGTCCA ACTTTGGTGA CGCATTGCTG 
GATGCCGGCG AGTCCATGAA GCGCCTGGCA GAGGTGAAGG ACTCCCTGGA CATCGAGGTC 
AAGCAGAACT TCATTGACCC CCTCCAGAAC CTGTGCGAGA AAGACCTGAA GGAGATCCAG 
CACCACCTGA AGAAACTGGA GGGCCGCCGC CTGGACTTTG ACTACAAGAA GAAGCGGCAG 
GGCAAGATCC CCGATGAGGA GCTACGCCAG GCGCTGGAGA AGTTCGAGGA GTCCAAGGAG 
GTGGCAGAAA CCAGCATGCA CAACCTCCTG GAGACTGACA TCGAGCAGGT GAGTCAGCTC 
TCGGCCCTGG TGGATGCACA GCTGGACTAC CACCGGCAGG CCGTGCAGAT CCTGGACGAG 
CTGGCGGAGA AGCTCAAGCG CAGGATGCGG GAAGCTTCCT CACGCCCTAA GCGGGAGTAT 
AAGCCCAAGC CCCGGGAGCC CTTTGACCTT GGAGAGCCTG AGCAGTCCAA CGGGGGCTTC 
CCCTGCACCA CAGCCCCCAA GATCGCAGCT TCATCGTCTT TCCGATCTTC CGACAAGCCC 
ATCCGGACCC CTAGCCGGAG CATGCCGCCC CTGGACCAGC CGAGCTGCAA GGCGCTGTAC 
GACTTCGAGC CCGAGAACGA CGGGGAGCTG GGCTTCCATG AGGGCGACGT CATCACGCTG 
ACCAACCAGA TCGATGAGAA CTGGTACGAG GGCATGCTGG ACGGCCAGTC GGGCTTCTTC 
CCGCTCAGCT ACGTGGAGGT GCTTGTGCCC CTGCCGCAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH3GL1 ( XM_017027146.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882635.1 Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu88670
Clone ID Related Accession (Same CDS sequence)	XM_017027146.1
Accession Version	XM_017027146.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	endophilin-A2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTGTGA CTCAGCTGGT CAGTGAGAAG GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT 
GATGACTTCA AAGAGATGGA GAAGAAGGTG GATGTCACCA GCAAGGCGGT GACAGAAGTG 
CTGGCCAGGA CCATCGAGTA CCTGCAGCCC AACCCAGCCT CGCGGGCTAA GCTGACCATG 
CTCAACACGG TGTCCAAGAT CCGGGGCCAG GTGAAGAACC CCGGCTACCC GCAGTCGGAG 
GGGCTTCTGG GCGAGTGCAT GATCCGCCAC GGGAAGGAGC TGGGCGGCGA GTCCAACTTT 
GGTGACGCAT TGCTGGATGC CGGCGAGTCC ATGAAGCGCC TGGCAGAGGT GAAGGACTCC 
CTGGACATCG AGGTCAAGCA GAACTTCATT GACCCCCTCC AGAACCTGTG CGAGAAAGAC 
CTGAAGGAGA TCCAGCACCA CCTGAAGAAA CTGGAGGGCC GCCGCCTGGA CTTTGACTAC 
AAGAAGAAGC GGCAGGGCAA GATCCCCGAT GAGGAGCTAC GCCAGGCGCT GGAGAAGTTC 
GAGGAGTCCA AGGAGGTGGC AGAAACCAGC ATGCACAACC TCCTGGAGAC TGACATCGAG 
CAGGTGAGTC AGCTCTCGGC CCTGGTGGAT GCACAGCTGG ACTACCACCG GCAGGCCGTG 
CAGATCCTGG ACGAGCTGGC GGAGAAGCTC AAGCGCAGGA TGCGGGAAGC TTCCTCACGC 
CCTAAGCGGG AGTATAAGCC CAAGCCCCGG GAGCCCTTTG ACCTTGGAGA GCCTGAGCAG 
TCCAACGGGG GCTTCCCCTG CACCACAGCC CCCAAGATCG CAGCTTCATC GTCTTTCCGA 
TCTTCCGACA AGCCCATCCG GACCCCTAGC CGGAGCATGC CGCCCCTGGA CCAGCCGAGC 
TGCAAGGCGC TGTACGACTT CGAGCCCGAG AACGACGGGG AGCTGGGCTT CCATGAGGGC 
GACGTCATCA CGCTGACCAA CCAGATCGAT GAGAACTGGT ACGAGGGCAT GCTGGACGGC 
CAGTCGGGCT TCTTCCCGCT CAGCTACGTG GAGGTGCTTG TGCCCCTGCC GCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882635.1
CDS	16..1092
Translation	MGVTQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVEVLVPLPQ

Target ORF information:

RefSeq Version	XM_017027146.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH3 domain containing GRB2 like 1, endophilin A2 (SH3GL1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027146.1

ORF Insert Sequence:

ATGGGTGTGA CTCAGCTGGT CAGTGAGAAG GTCGGAGGGG CCGAGGGGAC CAAGCTGGAT 
GATGACTTCA AAGAGATGGA GAAGAAGGTG GATGTCACCA GCAAGGCGGT GACAGAAGTG 
CTGGCCAGGA CCATCGAGTA CCTGCAGCCC AACCCAGCCT CGCGGGCTAA GCTGACCATG 
CTCAACACGG TGTCCAAGAT CCGGGGCCAG GTGAAGAACC CCGGCTACCC GCAGTCGGAG 
GGGCTTCTGG GCGAGTGCAT GATCCGCCAC GGGAAGGAGC TGGGCGGCGA GTCCAACTTT 
GGTGACGCAT TGCTGGATGC CGGCGAGTCC ATGAAGCGCC TGGCAGAGGT GAAGGACTCC 
CTGGACATCG AGGTCAAGCA GAACTTCATT GACCCCCTCC AGAACCTGTG CGAGAAAGAC 
CTGAAGGAGA TCCAGCACCA CCTGAAGAAA CTGGAGGGCC GCCGCCTGGA CTTTGACTAC 
AAGAAGAAGC GGCAGGGCAA GATCCCCGAT GAGGAGCTAC GCCAGGCGCT GGAGAAGTTC 
GAGGAGTCCA AGGAGGTGGC AGAAACCAGC ATGCACAACC TCCTGGAGAC TGACATCGAG 
CAGGTGAGTC AGCTCTCGGC CCTGGTGGAT GCACAGCTGG ACTACCACCG GCAGGCCGTG 
CAGATCCTGG ACGAGCTGGC GGAGAAGCTC AAGCGCAGGA TGCGGGAAGC TTCCTCACGC 
CCTAAGCGGG AGTATAAGCC CAAGCCCCGG GAGCCCTTTG ACCTTGGAGA GCCTGAGCAG 
TCCAACGGGG GCTTCCCCTG CACCACAGCC CCCAAGATCG CAGCTTCATC GTCTTTCCGA 
TCTTCCGACA AGCCCATCCG GACCCCTAGC CGGAGCATGC CGCCCCTGGA CCAGCCGAGC 
TGCAAGGCGC TGTACGACTT CGAGCCCGAG AACGACGGGG AGCTGGGCTT CCATGAGGGC 
GACGTCATCA CGCTGACCAA CCAGATCGAT GAGAACTGGT ACGAGGGCAT GCTGGACGGC 
CAGTCGGGCT TCTTCCCGCT CAGCTACGTG GAGGTGCTTG TGCCCCTGCC GCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Endophilin A2: A Potential Link to Adiposity and Beyond.
Molecules and cells40(11)855-863(2017 Nov)
Alfadda AA,Sallam RM,Gul R,Hwang I,Ka S

Endophilin A2 promotes HER2 internalization and sensitivity to trastuzumab-based therapy in HER2-positive breast cancers.
Breast cancer research : BCR19(1)110(2017 Oct)
Baldassarre T,Truesdell P,Craig AW

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SH3GL1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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