C19orf33 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	C19orf33
Entrez Gene ID	64073
Full Name	chromosome 19 open reading frame 33
Synonyms	H2RSP,IMUP,IMUP-1,IMUP-2
General protein information	Preferred Names chromosome 19 open reading frame 33 Names immortalization up-regulated protein HAI-2 related small protein hepatocyte growth factor activator inhibitor type 2-related small protein immortalization-upregulated protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2
Summary	The protein encoded by this gene has been shown to be upregulated in SV40-immortalized fibroblasts as well as in endometrial carcinoma cells. The encoded protein is found primarily in the nucleus. This protein may play a role in placental development and diseases such as pre-eclampsia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001317801.2	NP_001304730.1	immortalization up-regulated protein isoform IMUP-2
NM_033520.1	NP_277055.1	immortalization up-regulated protein
NM_033520.2	NP_277055.1	immortalization up-regulated protein isoform IMUP-1
NM_001317801.1	NP_001304730.1	immortalization up-regulated protein isoform IMUP-2
NM_033520.3	NP_277055.1	immortalization up-regulated protein isoform IMUP-1

Pathways from BioSystems

Homologies

	LOC714854	XP_001106691.1
Homo sapiens (human)	C19orf33	NP_277055.1

Gene Ontology
Bibliography

Related articles in PubMed

Hypoxia-induced downregulation of XIAP in trophoblasts mediates apoptosis via interaction with IMUP-2: implications for placental development during pre-eclampsia.
Jeon SY, Lee HJ, Na KH, Cha DH, Kim JK, Park JW, Yoon TK, Kim GJ
Journal of cellular biochemistry114(1)89-98(2013 Jan)

Increased immortalization-upregulated protein 2 (IMUP-2) by hypoxia induces apoptosis of the trophoblast and pre-eclampsia.
Jeon SY, Lee HJ, Park JM, Jung HM, Yoo JK, Lee HJ, Lee JS, Cha DH, Kim JK, Kim GJ
Journal of cellular biochemistry110(2)522-30(2010 May)

Imup-1 and imup-2 overexpression in endometrial carcinoma in Korean and Japanese populations.
Kim SJ, An HJ, Kim HJ, Jungs HM, Lee S, Ko JJ, Kim IH, Sakuragi N, Kim JK
Anticancer research28(2A)865-71(2008 Mar-Apr)

Clinical relevance of hepsin and hepatocyte growth factor activator inhibitor type 2 expression in renal cell carcinoma.
Betsunoh H, Mukai S, Akiyama Y, Fukushima T, Minamiguchi N, Hasui Y, Osada Y, Kataoka H
Cancer science98(4)491-8(2007 Apr)

Enhanced expression of hepatocyte growth factor activator inhibitor type 2-related small peptide at the invasive front of colon cancers.
Uchiyama S, Itoh H, Naganuma S, Nagaike K, Fukushima T, Tanaka H, Hamasuna R, Chijiiwa K, Kataoka H
Gut56(2)215-26(2007 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Hypoxia-induced down-regulation of XIAP mediates apoptosis in trophoblasts through interaction with increased IMUP-2; this mechanism underlies the pathogenesis of pre-eclampsia.
Title: Hypoxia-induced downregulation of XIAP in trophoblasts mediates apoptosis via interaction with IMUP-2: implications for placental development during pre-eclampsia.

results suggest that IMUP-2 expression is specifically elevated in preterm pre-eclampsia and under hypoxic conditions, and that IMUP-2 induces apoptosis of the trophoblast
Title: Increased immortalization-upregulated protein 2 (IMUP-2) by hypoxia induces apoptosis of the trophoblast and pre-eclampsia.

These findings demonstrate the up-regulation of imup-1 and imup-2 in human endometrial carcinomas and indicate that these molecules play a role in endometrial carcinogenesis in both Korean and Japanese patients.
Title: Imup-1 and imup-2 overexpression in endometrial carcinoma in Korean and Japanese populations.

Our findings suggest that the balance between hepsin and its inhibitor, HAI-2, may have prognostic value in RCC.
Title: Clinical relevance of hepsin and hepatocyte growth factor activator inhibitor type 2 expression in renal cell carcinoma.

Nuclear translocation of H2RSP may be related to a signaling involved in the transition from cellular proliferation to differentiation in experimental murine colitis.
Title: Nuclear translocation of H2RSP is impaired in regenerating intestinal epithelial cells of murine colitis model.

The following C19orf33 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C19orf33 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29896	NM_033520.3 Latest version!	Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu100451	NM_001317801.2 Latest version!	Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu29896	NM_033520.1	Homo sapiens chromosome 19 open reading frame 33 (C19orf33), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu100451	NM_001317801.1	Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu29896	NM_033520.2	Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

C19orf33 ( NM_033520.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_277055.1 Homo sapiens chromosome 19 open reading frame 33 (C19orf33), mRNA.

Price & Availability↑

CloneID	OHu29896
Clone ID Related Accession (Same CDS sequence)	NM_033520.1 , NM_033520.2 , NM_033520.3
Accession Version	NM_033520.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	immortalization up-regulated protein
Comment

ATGGAGTTCG ACCTGGGAGC AGCCCTGGAG CCCACCTCCC AGAAGCCCGG TGTGGGGGCG 
GGCCACGGGG GAGATCCCAA GCTCAGTCCC CACAAAGTTC AGGGCCGGTC GGAGGCAGGG 
GCAGGTCCGG GTCCAAAGCA AGGACACCAC AGCTCTTCCG ACTCCAGCAG CAGCTCCAGC 
GATTCGGACA CGGATGTGAA GTCCCACGCT GCTGGCTCCA AGCAGCACGA GAGCATCCCG 
GGCAAGGCCA AGAAGCCCAA AGTGAAGAAG AAGGAGAAGG GCAAGAAGGA GAAGGGCAAG 
AAGAAGGAGG CTCCCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_277055.1
Translation	MEFDLGAALEPTSQKPGVGAGHGGDPKLSPHKVQGRSEAGAGPGPKQGHHSSSDSSSSSSDSDTDVKSHAAGSKQHESIPGKAKKPKVKKKEKGKKEKGKKKEAPH

Target ORF information:

RefSeq Version	NM_033520.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens chromosome 19 open reading frame 33 (C19orf33), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033520.1

ORF Insert Sequence:

ATGGAGTTCG ACCTGGGAGC AGCCCTGGAG CCCACCTCCC AGAAGCCCGG TGTGGGGGCG 
GGCCACGGGG GAGATCCCAA GCTCAGTCCC CACAAAGTTC AGGGCCGGTC GGAGGCAGGG 
GCAGGTCCGG GTCCAAAGCA AGGACACCAC AGCTCTTCCG ACTCCAGCAG CAGCTCCAGC 
GATTCGGACA CGGATGTGAA GTCCCACGCT GCTGGCTCCA AGCAGCACGA GAGCATCCCG 
GGCAAGGCCA AGAAGCCCAA AGTGAAGAAG AAGGAGAAGG GCAAGAAGGA GAAGGGCAAG 
AAGAAGGAGG CTCCCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C19orf33 ( NM_033520.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_277055.1 Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29896
Clone ID Related Accession (Same CDS sequence)	NM_033520.1 , NM_033520.2 , NM_033520.3
Accession Version	NM_033520.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	immortalization up-regulated protein isoform IMUP-1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF213678.1 and CB109881.1. On Dec 10, 2015 this sequence version replaced NM_033520.1. Transcript Variant: This variant (1) encodes the longer isoform (IMUP-1). ##Evidence-Data-START## Transcript exon combination :: AF213678.1, HY179188.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGTTCG ACCTGGGAGC AGCCCTGGAG CCCACCTCCC AGAAGCCCGG TGTGGGGGCG 
GGCCACGGGG GAGATCCCAA GCTCAGTCCC CACAAAGTTC AGGGCCGGTC GGAGGCAGGG 
GCAGGTCCGG GTCCAAAGCA AGGACACCAC AGCTCTTCCG ACTCCAGCAG CAGCTCCAGC 
GATTCGGACA CGGATGTGAA GTCCCACGCT GCTGGCTCCA AGCAGCACGA GAGCATCCCG 
GGCAAGGCCA AGAAGCCCAA AGTGAAGAAG AAGGAGAAGG GCAAGAAGGA GAAGGGCAAG 
AAGAAGGAGG CTCCCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_277055.1
CDS	102..422
Translation	MEFDLGAALEPTSQKPGVGAGHGGDPKLSPHKVQGRSEAGAGPGPKQGHHSSSDSSSSSSDSDTDVKSHAAGSKQHESIPGKAKKPKVKKKEKGKKEKGKKKEAPH

Target ORF information:

RefSeq Version	NM_033520.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033520.2

ORF Insert Sequence:

ATGGAGTTCG ACCTGGGAGC AGCCCTGGAG CCCACCTCCC AGAAGCCCGG TGTGGGGGCG 
GGCCACGGGG GAGATCCCAA GCTCAGTCCC CACAAAGTTC AGGGCCGGTC GGAGGCAGGG 
GCAGGTCCGG GTCCAAAGCA AGGACACCAC AGCTCTTCCG ACTCCAGCAG CAGCTCCAGC 
GATTCGGACA CGGATGTGAA GTCCCACGCT GCTGGCTCCA AGCAGCACGA GAGCATCCCG 
GGCAAGGCCA AGAAGCCCAA AGTGAAGAAG AAGGAGAAGG GCAAGAAGGA GAAGGGCAAG 
AAGAAGGAGG CTCCCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C19orf33 ( NM_033520.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_277055.1 Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29896
Clone ID Related Accession (Same CDS sequence)	NM_033520.1 , NM_033520.2 , NM_033520.3
Accession Version	NM_033520.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 321bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	immortalization up-regulated protein isoform IMUP-1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF213678.1 and CB109881.1. On Nov 22, 2018 this sequence version replaced NM_033520.2. Transcript Variant: This variant (1) encodes the longer isoform (IMUP-1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB038317.1, BG287159.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000301246.10/ ENSP00000301246.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGTTCG ACCTGGGAGC AGCCCTGGAG CCCACCTCCC AGAAGCCCGG TGTGGGGGCG 
GGCCACGGGG GAGATCCCAA GCTCAGTCCC CACAAAGTTC AGGGCCGGTC GGAGGCAGGG 
GCAGGTCCGG GTCCAAAGCA AGGACACCAC AGCTCTTCCG ACTCCAGCAG CAGCTCCAGC 
GATTCGGACA CGGATGTGAA GTCCCACGCT GCTGGCTCCA AGCAGCACGA GAGCATCCCG 
GGCAAGGCCA AGAAGCCCAA AGTGAAGAAG AAGGAGAAGG GCAAGAAGGA GAAGGGCAAG 
AAGAAGGAGG CTCCCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_277055.1
CDS	12..332
Translation	MEFDLGAALEPTSQKPGVGAGHGGDPKLSPHKVQGRSEAGAGPGPKQGHHSSSDSSSSSSDSDTDVKSHAAGSKQHESIPGKAKKPKVKKKEKGKKEKGKKKEAPH

Target ORF information:

RefSeq Version	NM_033520.3
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033520.3

ORF Insert Sequence:

ATGGAGTTCG ACCTGGGAGC AGCCCTGGAG CCCACCTCCC AGAAGCCCGG TGTGGGGGCG 
GGCCACGGGG GAGATCCCAA GCTCAGTCCC CACAAAGTTC AGGGCCGGTC GGAGGCAGGG 
GCAGGTCCGG GTCCAAAGCA AGGACACCAC AGCTCTTCCG ACTCCAGCAG CAGCTCCAGC 
GATTCGGACA CGGATGTGAA GTCCCACGCT GCTGGCTCCA AGCAGCACGA GAGCATCCCG 
GGCAAGGCCA AGAAGCCCAA AGTGAAGAAG AAGGAGAAGG GCAAGAAGGA GAAGGGCAAG 
AAGAAGGAGG CTCCCCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C19orf33 ( NM_001317801.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001304730.1 Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu100451
Clone ID Related Accession (Same CDS sequence)	NM_001317801.2 , NM_001317801.1
Accession Version	NM_001317801.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	immortalization up-regulated protein isoform IMUP-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC060319.1 and CB109881.1. On Jun 1, 2019 this sequence version replaced NM_001317801.1. Transcript Variant: This variant (2) uses an alternate splice junction compared to variant 1, that causes a frameshift. The resulting isoform (IMUP-2) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU958067.1, AA705936.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGTTCG ACCTGGGAGC AGCCCTGGAG CCCACCTCCC AGAAGCCCGG TGTGGGGGCG 
GGCCACGGGG GAGATCCCAA GCTCAGTCCC CACAAAGTTC AGGGCCGGTC GGAGGCAGGG 
GCAGGTCCGG GTCCAAAGGC CTCCAACTTC AGGGGGCTGG GTAAGGGGCG CCGCCTCACT 
GCCGCACCTC CATCCAGCAA GGACACCACA GCTCTTCCGA CTCCAGCAGC AGCTCCAGCG 
ATTCGGACAC GGATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001304730.1
CDS	12..269
Translation	MEFDLGAALEPTSQKPGVGAGHGGDPKLSPHKVQGRSEAGAGPGPKASNFRGLGKGRRLTAAPPSSKDTTALPTPAAAPAIRTRM

Target ORF information:

RefSeq Version	NM_001317801.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001317801.2

ORF Insert Sequence:

ATGGAGTTCG ACCTGGGAGC AGCCCTGGAG CCCACCTCCC AGAAGCCCGG TGTGGGGGCG 
GGCCACGGGG GAGATCCCAA GCTCAGTCCC CACAAAGTTC AGGGCCGGTC GGAGGCAGGG 
GCAGGTCCGG GTCCAAAGGC CTCCAACTTC AGGGGGCTGG GTAAGGGGCG CCGCCTCACT 
GCCGCACCTC CATCCAGCAA GGACACCACA GCTCTTCCGA CTCCAGCAGC AGCTCCAGCG 
ATTCGGACAC GGATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C19orf33 ( NM_001317801.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001304730.1 Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu100451
Clone ID Related Accession (Same CDS sequence)	NM_001317801.2 , NM_001317801.1
Accession Version	NM_001317801.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	immortalization up-regulated protein isoform IMUP-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF213678.1, BC060319.1 and CB109881.1. Transcript Variant: This variant (2) uses an alternate splice junction compared to variant 1, that causes a frameshift. The resulting isoform (IMUP-2) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU958067.1, AB038318.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGTTCG ACCTGGGAGC AGCCCTGGAG CCCACCTCCC AGAAGCCCGG TGTGGGGGCG 
GGCCACGGGG GAGATCCCAA GCTCAGTCCC CACAAAGTTC AGGGCCGGTC GGAGGCAGGG 
GCAGGTCCGG GTCCAAAGGC CTCCAACTTC AGGGGGCTGG GTAAGGGGCG CCGCCTCACT 
GCCGCACCTC CATCCAGCAA GGACACCACA GCTCTTCCGA CTCCAGCAGC AGCTCCAGCG 
ATTCGGACAC GGATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001304730.1
CDS	102..359
Translation	MEFDLGAALEPTSQKPGVGAGHGGDPKLSPHKVQGRSEAGAGPGPKASNFRGLGKGRRLTAAPPSSKDTTALPTPAAAPAIRTRM

Target ORF information:

RefSeq Version	NM_001317801.1
Organism	Homo sapiens(human)
Definition	Homo sapiens chromosome 19 open reading frame 33 (C19orf33), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001317801.1

ORF Insert Sequence:

ATGGAGTTCG ACCTGGGAGC AGCCCTGGAG CCCACCTCCC AGAAGCCCGG TGTGGGGGCG 
GGCCACGGGG GAGATCCCAA GCTCAGTCCC CACAAAGTTC AGGGCCGGTC GGAGGCAGGG 
GCAGGTCCGG GTCCAAAGGC CTCCAACTTC AGGGGGCTGG GTAAGGGGCG CCGCCTCACT 
GCCGCACCTC CATCCAGCAA GGACACCACA GCTCTTCCGA CTCCAGCAGC AGCTCCAGCG 
ATTCGGACAC GGATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hypoxia-induced downregulation of XIAP in trophoblasts mediates apoptosis via interaction with IMUP-2: implications for placental development during pre-eclampsia.
Journal of cellular biochemistry114(1)89-98(2013 Jan)
Jeon SY,Lee HJ,Na KH,Cha DH,Kim JK,Park JW,Yoon TK,Kim GJ

Increased immortalization-upregulated protein 2 (IMUP-2) by hypoxia induces apoptosis of the trophoblast and pre-eclampsia.
Journal of cellular biochemistry110(2)522-30(2010 May)
Jeon SY,Lee HJ,Park JM,Jung HM,Yoo JK,Lee HJ,Lee JS,Cha DH,Kim JK,Kim GJ

Imup-1 and imup-2 overexpression in endometrial carcinoma in Korean and Japanese populations.
Anticancer research28(2A)865-71(2008 Mar-Apr)
Kim SJ,An HJ,Kim HJ,Jungs HM,Lee S,Ko JJ,Kim IH,Sakuragi N,Kim JK

Clinical relevance of hepsin and hepatocyte growth factor activator inhibitor type 2 expression in renal cell carcinoma.
Cancer science98(4)491-8(2007 Apr)
Betsunoh H,Mukai S,Akiyama Y,Fukushima T,Minamiguchi N,Hasui Y,Osada Y,Kataoka H

Enhanced expression of hepatocyte growth factor activator inhibitor type 2-related small peptide at the invasive front of colon cancers.
Gut56(2)215-26(2007 Feb)
Uchiyama S,Itoh H,Naganuma S,Nagaike K,Fukushima T,Tanaka H,Hamasuna R,Chijiiwa K,Kataoka H

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C19orf33 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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