RET cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RET
Entrez Gene ID	5979
Full Name	ret proto-oncogene
Synonyms	CDHF12,CDHR16,HSCR1,MEN2A,MEN2B,MTC1,PTC,RET-ELE1
General protein information	Preferred Names ret proto-oncogene Names proto-oncogene tyrosine-protein kinase receptor Ret RET receptor tyrosine kinase cadherin family member 12 cadherin-related family member 16 proto-oncogene c-Ret rearranged during transfection ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q11.21
Summary	This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis. [provided by RefSeq, Sep 2017].
Disorder MIM:	164761
Disorder Html:	Multiple endocrine neoplasia IIA, 171400 (3); Medullary thyroid carcinoma, 155240 (3); Multiple endocrine neoplasia IIB, 162300 (3); Central hypoventilation syndrome, congenital, 209880 (3); Pheochromocytoma, 171300 (3); {Hirschsprung disease, susceptibility to, 1}, 142623 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001355216.1	NP_001342145.1	proto-oncogene tyrosine-protein kinase receptor Ret isoform d
NM_020975.5	NP_066124.1	proto-oncogene tyrosine-protein kinase receptor Ret isoform a precursor
NM_020975.4	NP_066124.1	proto-oncogene tyrosine-protein kinase receptor Ret isoform a precursor
NM_020630.5	NP_065681.1	proto-oncogene tyrosine-protein kinase receptor Ret isoform c precursor
NM_020630.4	NP_065681.1	proto-oncogene tyrosine-protein kinase receptor Ret isoform c precursor
NM_020975.6	NP_066124.1	proto-oncogene tyrosine-protein kinase receptor Ret isoform a precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RET	NP_001184028.1
Bos taurus (cattle)	RET	NP_001178412.1
Homo sapiens (human)	RET	NP_066124.1
	RET	XP_002805672.1
Rattus norvegicus (Norway rat)	Ret	NP_036775.2
Danio rerio (zebrafish)	ret	NP_858048.2
Pan troglodytes (chimpanzee)	RET	XP_003312612.1
Mus musculus (house mouse)	Ret	NP_033076.2
Xenopus tropicalis (tropical clawed frog)	ret	XP_002933941.2
Gallus gallus (chicken)	RET	NP_990521.1

Gene Ontology
Bibliography

Related articles in PubMed

Associations between RET tagSNPs and their haplotypes and susceptibility, clinical severity, and thyroid function in patients with differentiated thyroid cancer.
He C, Ma J, Jiang Y, Su X, Zhang X, Chen W, Ye Z, Deng T, Deng W, Yang A
PloS one12(11)e0187968(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

RET expression was significantly greater in patients with Extraskeletal myxoid chondrosarcoma relative to other types of sarcomas except for liposarcoma
Title: Next generation sequencing of extraskeletal myxoid chondrosarcoma.

Significant genetic risk for Hirschsprung disease (HSCR) was imparted by rs2435357 and rs2506030 at RET and by rs12707682 at SEMA3 in a Chinese population. No evidence was found of a genetic association between HSCR and either of the NRG1 SNPs rs7835688 and rs16879552, at either allele or genotype level.
Title: Cumulative Risk Impact of RET, SEMA3, and NRG1 Polymorphisms Associated With Hirschsprung Disease in Han Chinese.

We also demonstrate that the effects of RET and NRG1 are universal across European and Asian ancestries. In contrast, we detected a European-specific association of a low-frequency variant, rs80227144, in SEMA3. Conditional analyses on the lead SNPs revealed a secondary association signal, corresponding to an Asian-specific, low-frequency missense variant encoding RET p.Asp489Asn
Title: Trans-ethnic meta-analysis of genome-wide association studies for Hirschsprung disease.

family members with MEN2A should undergo RET-PO testing as early as possible, asymptomatic carriers should be regularly followed up, and surgery should be performed when lesions are detected.
Title: Clinical significance of RET mutation screening in a pedigree of multiple endocrine neoplasia type 2A.

Up-regulation of RET expression is associated with medullary thyroid carcinoma.
Title: Germline ESR2 mutation predisposes to medullary thyroid carcinoma and causes up-regulation of RET expression.

The following RET gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RET cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27214	NM_020975.4 Latest version!	Homo sapiens ret proto-oncogene (RET), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu27273	NM_020630.4 Latest version!	Homo sapiens ret proto-oncogene (RET), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu60238	NM_020975.6 Latest version!	Homo sapiens ret proto-oncogene (RET), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
OHu102961	NM_001355216.1 Latest version!	Homo sapiens ret proto-oncogene (RET), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu102970	NM_020630.5 Latest version!	Homo sapiens ret proto-oncogene (RET), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
View Old Accession Versions >>
OHu60238	NM_020975.5	Homo sapiens ret proto-oncogene (RET), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RET ( NM_020975.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_066124.1 Homo sapiens ret proto-oncogene (RET), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu27214
Clone ID Related Accession (Same CDS sequence)	NM_020975.4
Accession Version	NM_020975.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3345bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-22
Organism	Homo sapiens(Human)
Product	proto-oncogene tyrosine-protein kinase receptor Ret isoform a precursor
Comment	REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA100452.1, BC003072.2, BC004257.1, X12949.1, AC010864.11 and BM661773.1. This sequence is a reference standard in the RefSeqGene project. On Feb 27, 2007 this sequence version replaced NM_020975.3. Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (a). This isoform is also known as Ret51. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAAGG CGACGTCCGG TGCCGCGGGG CTGCGTCTGC TGTTGCTGCT GCTGCTGCCG 
CTGCTAGGCA AAGTGGCATT GGGCCTCTAC TTCTCGAGGG ATGCTTACTG GGAGAAGCTG 
TATGTGGACC AGGCGGCCGG CACGCCCTTG CTGTACGTCC ATGCCCTGCG GGACGCCCCT 
GAGGAGGTGC CCAGCTTCCG CCTGGGCCAG CATCTCTACG GCACGTACCG CACACGGCTG 
CATGAGAACA ACTGGATCTG CATCCAGGAG GACACCGGCC TCCTCTACCT TAACCGGAGC 
CTGGACCATA GCTCCTGGGA GAAGCTCAGT GTCCGCAACC GCGGCTTTCC CCTGCTCACC 
GTCTACCTCA AGGTCTTCCT GTCACCCACA TCCCTTCGTG AGGGCGAGTG CCAGTGGCCA 
GGCTGTGCCC GCGTATACTT CTCCTTCTTC AACACCTCCT TTCCAGCCTG CAGCTCCCTC 
AAGCCCCGGG AGCTCTGCTT CCCAGAGACA AGGCCCTCCT TCCGCATTCG GGAGAACCGA 
CCCCCAGGCA CCTTCCACCA GTTCCGCCTG CTGCCTGTGC AGTTCTTGTG CCCCAACATC 
AGCGTGGCCT ACAGGCTCCT GGAGGGTGAG GGTCTGCCCT TCCGCTGCGC CCCGGACAGC 
CTGGAGGTGA GCACGCGCTG GGCCCTGGAC CGCGAGCAGC GGGAGAAGTA CGAGCTGGTG 
GCCGTGTGCA CCGTGCACGC CGGCGCGCGC GAGGAGGTGG TGATGGTGCC CTTCCCGGTG 
ACCGTGTACG ACGAGGACGA CTCGGCGCCC ACCTTCCCCG CGGGCGTCGA CACCGCCAGC 
GCCGTGGTGG AGTTCAAGCG GAAGGAGGAC ACCGTGGTGG CCACGCTGCG TGTCTTCGAT 
GCAGACGTGG TACCTGCATC AGGGGAGCTG GTGAGGCGGT ACACAAGCAC GCTGCTCCCC 
GGGGACACCT GGGCCCAGCA GACCTTCCGG GTGGAACACT GGCCCAACGA GACCTCGGTC 
CAGGCCAACG GCAGCTTCGT GCGGGCGACC GTACATGACT ATAGGCTGGT TCTCAACCGG 
AACCTCTCCA TCTCGGAGAA CCGCACCATG CAGCTGGCGG TGCTGGTCAA TGACTCAGAC 
TTCCAGGGCC CAGGAGCGGG CGTCCTCTTG CTCCACTTCA ACGTGTCGGT GCTGCCGGTC 
AGCCTGCACC TGCCCAGTAC CTACTCCCTC TCCGTGAGCA GGAGGGCTCG CCGATTTGCC 
CAGATCGGGA AAGTCTGTGT GGAAAACTGC CAGGCATTCA GTGGCATCAA CGTCCAGTAC 
AAGCTGCATT CCTCTGGTGC CAACTGCAGC ACGCTAGGGG TGGTCACCTC AGCCGAGGAC 
ACCTCGGGGA TCCTGTTTGT GAATGACACC AAGGCCCTGC GGCGGCCCAA GTGTGCCGAA 
CTTCACTACA TGGTGGTGGC CACCGACCAG CAGACCTCTA GGCAGGCCCA GGCCCAGCTG 
CTTGTAACAG TGGAGGGGTC ATATGTGGCC GAGGAGGCGG GCTGCCCCCT GTCCTGTGCA 
GTCAGCAAGA GACGGCTGGA GTGTGAGGAG TGTGGCGGCC TGGGCTCCCC AACAGGCAGG 
TGTGAGTGGA GGCAAGGAGA TGGCAAAGGG ATCACCAGGA ACTTCTCCAC CTGCTCTCCC 
AGCACCAAGA CCTGCCCCGA CGGCCACTGC GATGTTGTGG AGACCCAAGA CATCAACATT 
TGCCCTCAGG ACTGCCTCCG GGGCAGCATT GTTGGGGGAC ACGAGCCTGG GGAGCCCCGG 
GGGATTAAAG CTGGCTATGG CACCTGCAAC TGCTTCCCTG AGGAGGAGAA GTGCTTCTGC 
GAGCCCGAAG ACATCCAGGA TCCACTGTGC GACGAGCTGT GCCGCACGGT GATCGCAGCC 
GCTGTCCTCT TCTCCTTCAT CGTCTCGGTG CTGCTGTCTG CCTTCTGCAT CCACTGCTAC 
CACAAGTTTG CCCACAAGCC ACCCATCTCC TCAGCTGAGA TGACCTTCCG GAGGCCCGCC 
CAGGCCTTCC CGGTCAGCTA CTCCTCTTCC GGTGCCCGCC GGCCCTCGCT GGACTCCATG 
GAGAACCAGG TCTCCGTGGA TGCCTTCAAG ATCCTGGAGG ATCCAAAGTG GGAATTCCCT 
CGGAAGAACT TGGTTCTTGG AAAAACTCTA GGAGAAGGCG AATTTGGAAA AGTGGTCAAG 
GCAACGGCCT TCCATCTGAA AGGCAGAGCA GGGTACACCA CGGTGGCCGT GAAGATGCTG 
AAAGAGAACG CCTCCCCGAG TGAGCTTCGA GACCTGCTGT CAGAGTTCAA CGTCCTGAAG 
CAGGTCAACC ACCCACATGT CATCAAATTG TATGGGGCCT GCAGCCAGGA TGGCCCGCTC 
CTCCTCATCG TGGAGTACGC CAAATACGGC TCCCTGCGGG GCTTCCTCCG CGAGAGCCGC 
AAAGTGGGGC CTGGCTACCT GGGCAGTGGA GGCAGCCGCA ACTCCAGCTC CCTGGACCAC 
CCGGATGAGC GGGCCCTCAC CATGGGCGAC CTCATCTCAT TTGCCTGGCA GATCTCACAG 
GGGATGCAGT ATCTGGCCGA GATGAAGCTC GTTCATCGGG ACTTGGCAGC CAGAAACATC 
CTGGTAGCTG AGGGGCGGAA GATGAAGATT TCGGATTTCG GCTTGTCCCG AGATGTTTAT 
GAAGAGGATT CCTACGTGAA GAGGAGCCAG GGTCGGATTC CAGTTAAATG GATGGCAATT 
GAATCCCTTT TTGATCATAT CTACACCACG CAAAGTGATG TATGGTCTTT TGGTGTCCTG 
CTGTGGGAGA TCGTGACCCT AGGGGGAAAC CCCTATCCTG GGATTCCTCC TGAGCGGCTC 
TTCAACCTTC TGAAGACCGG CCACCGGATG GAGAGGCCAG ACAACTGCAG CGAGGAGATG 
TACCGCCTGA TGCTGCAATG CTGGAAGCAG GAGCCGGACA AAAGGCCGGT GTTTGCGGAC 
ATCAGCAAAG ACCTGGAGAA GATGATGGTT AAGAGGAGAG ACTACTTGGA CCTTGCGGCG 
TCCACTCCAT CTGACTCCCT GATTTATGAC GACGGCCTCT CAGAGGAGGA GACACCGCTG 
GTGGACTGTA ATAATGCCCC CCTCCCTCGA GCCCTCCCTT CCACATGGAT TGAAAACAAA 
CTCTATGGCA TGTCAGACCC GAACTGGCCT GGAGAGAGTC CTGTACCACT CACGAGAGCT 
GATGGCACTA ACACTGGGTT TCCAAGATAT CCAAATGATA GTGTATATGC TAACTGGATG 
CTTTCACCCT CAGCGGCAAA ATTAATGGAC ACGTTTGATA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066124.1
CDS	191..3535
Translation	MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELVAVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRYPNDSVYANWMLSPSAAKLMDTFDS

Target ORF information:

RefSeq Version	NM_020975.4
Organism	Homo sapiens(Human)
Definition	Homo sapiens ret proto-oncogene (RET), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020975.4

ORF Insert Sequence:

ATGGCGAAGG CGACGTCCGG TGCCGCGGGG CTGCGTCTGC TGTTGCTGCT GCTGCTGCCG 
CTGCTAGGCA AAGTGGCATT GGGCCTCTAC TTCTCGAGGG ATGCTTACTG GGAGAAGCTG 
TATGTGGACC AGGCGGCCGG CACGCCCTTG CTGTACGTCC ATGCCCTGCG GGACGCCCCT 
GAGGAGGTGC CCAGCTTCCG CCTGGGCCAG CATCTCTACG GCACGTACCG CACACGGCTG 
CATGAGAACA ACTGGATCTG CATCCAGGAG GACACCGGCC TCCTCTACCT TAACCGGAGC 
CTGGACCATA GCTCCTGGGA GAAGCTCAGT GTCCGCAACC GCGGCTTTCC CCTGCTCACC 
GTCTACCTCA AGGTCTTCCT GTCACCCACA TCCCTTCGTG AGGGCGAGTG CCAGTGGCCA 
GGCTGTGCCC GCGTATACTT CTCCTTCTTC AACACCTCCT TTCCAGCCTG CAGCTCCCTC 
AAGCCCCGGG AGCTCTGCTT CCCAGAGACA AGGCCCTCCT TCCGCATTCG GGAGAACCGA 
CCCCCAGGCA CCTTCCACCA GTTCCGCCTG CTGCCTGTGC AGTTCTTGTG CCCCAACATC 
AGCGTGGCCT ACAGGCTCCT GGAGGGTGAG GGTCTGCCCT TCCGCTGCGC CCCGGACAGC 
CTGGAGGTGA GCACGCGCTG GGCCCTGGAC CGCGAGCAGC GGGAGAAGTA CGAGCTGGTG 
GCCGTGTGCA CCGTGCACGC CGGCGCGCGC GAGGAGGTGG TGATGGTGCC CTTCCCGGTG 
ACCGTGTACG ACGAGGACGA CTCGGCGCCC ACCTTCCCCG CGGGCGTCGA CACCGCCAGC 
GCCGTGGTGG AGTTCAAGCG GAAGGAGGAC ACCGTGGTGG CCACGCTGCG TGTCTTCGAT 
GCAGACGTGG TACCTGCATC AGGGGAGCTG GTGAGGCGGT ACACAAGCAC GCTGCTCCCC 
GGGGACACCT GGGCCCAGCA GACCTTCCGG GTGGAACACT GGCCCAACGA GACCTCGGTC 
CAGGCCAACG GCAGCTTCGT GCGGGCGACC GTACATGACT ATAGGCTGGT TCTCAACCGG 
AACCTCTCCA TCTCGGAGAA CCGCACCATG CAGCTGGCGG TGCTGGTCAA TGACTCAGAC 
TTCCAGGGCC CAGGAGCGGG CGTCCTCTTG CTCCACTTCA ACGTGTCGGT GCTGCCGGTC 
AGCCTGCACC TGCCCAGTAC CTACTCCCTC TCCGTGAGCA GGAGGGCTCG CCGATTTGCC 
CAGATCGGGA AAGTCTGTGT GGAAAACTGC CAGGCATTCA GTGGCATCAA CGTCCAGTAC 
AAGCTGCATT CCTCTGGTGC CAACTGCAGC ACGCTAGGGG TGGTCACCTC AGCCGAGGAC 
ACCTCGGGGA TCCTGTTTGT GAATGACACC AAGGCCCTGC GGCGGCCCAA GTGTGCCGAA 
CTTCACTACA TGGTGGTGGC CACCGACCAG CAGACCTCTA GGCAGGCCCA GGCCCAGCTG 
CTTGTAACAG TGGAGGGGTC ATATGTGGCC GAGGAGGCGG GCTGCCCCCT GTCCTGTGCA 
GTCAGCAAGA GACGGCTGGA GTGTGAGGAG TGTGGCGGCC TGGGCTCCCC AACAGGCAGG 
TGTGAGTGGA GGCAAGGAGA TGGCAAAGGG ATCACCAGGA ACTTCTCCAC CTGCTCTCCC 
AGCACCAAGA CCTGCCCCGA CGGCCACTGC GATGTTGTGG AGACCCAAGA CATCAACATT 
TGCCCTCAGG ACTGCCTCCG GGGCAGCATT GTTGGGGGAC ACGAGCCTGG GGAGCCCCGG 
GGGATTAAAG CTGGCTATGG CACCTGCAAC TGCTTCCCTG AGGAGGAGAA GTGCTTCTGC 
GAGCCCGAAG ACATCCAGGA TCCACTGTGC GACGAGCTGT GCCGCACGGT GATCGCAGCC 
GCTGTCCTCT TCTCCTTCAT CGTCTCGGTG CTGCTGTCTG CCTTCTGCAT CCACTGCTAC 
CACAAGTTTG CCCACAAGCC ACCCATCTCC TCAGCTGAGA TGACCTTCCG GAGGCCCGCC 
CAGGCCTTCC CGGTCAGCTA CTCCTCTTCC GGTGCCCGCC GGCCCTCGCT GGACTCCATG 
GAGAACCAGG TCTCCGTGGA TGCCTTCAAG ATCCTGGAGG ATCCAAAGTG GGAATTCCCT 
CGGAAGAACT TGGTTCTTGG AAAAACTCTA GGAGAAGGCG AATTTGGAAA AGTGGTCAAG 
GCAACGGCCT TCCATCTGAA AGGCAGAGCA GGGTACACCA CGGTGGCCGT GAAGATGCTG 
AAAGAGAACG CCTCCCCGAG TGAGCTTCGA GACCTGCTGT CAGAGTTCAA CGTCCTGAAG 
CAGGTCAACC ACCCACATGT CATCAAATTG TATGGGGCCT GCAGCCAGGA TGGCCCGCTC 
CTCCTCATCG TGGAGTACGC CAAATACGGC TCCCTGCGGG GCTTCCTCCG CGAGAGCCGC 
AAAGTGGGGC CTGGCTACCT GGGCAGTGGA GGCAGCCGCA ACTCCAGCTC CCTGGACCAC 
CCGGATGAGC GGGCCCTCAC CATGGGCGAC CTCATCTCAT TTGCCTGGCA GATCTCACAG 
GGGATGCAGT ATCTGGCCGA GATGAAGCTC GTTCATCGGG ACTTGGCAGC CAGAAACATC 
CTGGTAGCTG AGGGGCGGAA GATGAAGATT TCGGATTTCG GCTTGTCCCG AGATGTTTAT 
GAAGAGGATT CCTACGTGAA GAGGAGCCAG GGTCGGATTC CAGTTAAATG GATGGCAATT 
GAATCCCTTT TTGATCATAT CTACACCACG CAAAGTGATG TATGGTCTTT TGGTGTCCTG 
CTGTGGGAGA TCGTGACCCT AGGGGGAAAC CCCTATCCTG GGATTCCTCC TGAGCGGCTC 
TTCAACCTTC TGAAGACCGG CCACCGGATG GAGAGGCCAG ACAACTGCAG CGAGGAGATG 
TACCGCCTGA TGCTGCAATG CTGGAAGCAG GAGCCGGACA AAAGGCCGGT GTTTGCGGAC 
ATCAGCAAAG ACCTGGAGAA GATGATGGTT AAGAGGAGAG ACTACTTGGA CCTTGCGGCG 
TCCACTCCAT CTGACTCCCT GATTTATGAC GACGGCCTCT CAGAGGAGGA GACACCGCTG 
GTGGACTGTA ATAATGCCCC CCTCCCTCGA GCCCTCCCTT CCACATGGAT TGAAAACAAA 
CTCTATGGCA TGTCAGACCC GAACTGGCCT GGAGAGAGTC CTGTACCACT CACGAGAGCT 
GATGGCACTA ACACTGGGTT TCCAAGATAT CCAAATGATA GTGTATATGC TAACTGGATG 
CTTTCACCCT CAGCGGCAAA ATTAATGGAC ACGTTTGATA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RET ( NM_020630.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_065681.1 Homo sapiens ret proto-oncogene (RET), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu27273
Clone ID Related Accession (Same CDS sequence)	NM_020630.4
Accession Version	NM_020630.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3219bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-29
Organism	Homo sapiens(Human)
Product	proto-oncogene tyrosine-protein kinase receptor Ret isoform c precursor
Comment	REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA100452.1, BC003072.2, BC004257.1, X12949.1, DA911581.1, BM703293.1, BE261914.1 and AI472270.1. This sequence is a reference standard in the RefSeqGene project. On Feb 27, 2007 this sequence version replaced NM_020630.3. Transcript Variant: This variant (4) differs in the 3' UTR and coding region compared to variant 2. The resulting isoform (c) is shorter and has a distinct C-terminus compared to isoform a. This isoform is also known as Ret9. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC004257.1, SRR1803617.37059.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAAGG CGACGTCCGG TGCCGCGGGG CTGCGTCTGC TGTTGCTGCT GCTGCTGCCG 
CTGCTAGGCA AAGTGGCATT GGGCCTCTAC TTCTCGAGGG ATGCTTACTG GGAGAAGCTG 
TATGTGGACC AGGCGGCCGG CACGCCCTTG CTGTACGTCC ATGCCCTGCG GGACGCCCCT 
GAGGAGGTGC CCAGCTTCCG CCTGGGCCAG CATCTCTACG GCACGTACCG CACACGGCTG 
CATGAGAACA ACTGGATCTG CATCCAGGAG GACACCGGCC TCCTCTACCT TAACCGGAGC 
CTGGACCATA GCTCCTGGGA GAAGCTCAGT GTCCGCAACC GCGGCTTTCC CCTGCTCACC 
GTCTACCTCA AGGTCTTCCT GTCACCCACA TCCCTTCGTG AGGGCGAGTG CCAGTGGCCA 
GGCTGTGCCC GCGTATACTT CTCCTTCTTC AACACCTCCT TTCCAGCCTG CAGCTCCCTC 
AAGCCCCGGG AGCTCTGCTT CCCAGAGACA AGGCCCTCCT TCCGCATTCG GGAGAACCGA 
CCCCCAGGCA CCTTCCACCA GTTCCGCCTG CTGCCTGTGC AGTTCTTGTG CCCCAACATC 
AGCGTGGCCT ACAGGCTCCT GGAGGGTGAG GGTCTGCCCT TCCGCTGCGC CCCGGACAGC 
CTGGAGGTGA GCACGCGCTG GGCCCTGGAC CGCGAGCAGC GGGAGAAGTA CGAGCTGGTG 
GCCGTGTGCA CCGTGCACGC CGGCGCGCGC GAGGAGGTGG TGATGGTGCC CTTCCCGGTG 
ACCGTGTACG ACGAGGACGA CTCGGCGCCC ACCTTCCCCG CGGGCGTCGA CACCGCCAGC 
GCCGTGGTGG AGTTCAAGCG GAAGGAGGAC ACCGTGGTGG CCACGCTGCG TGTCTTCGAT 
GCAGACGTGG TACCTGCATC AGGGGAGCTG GTGAGGCGGT ACACAAGCAC GCTGCTCCCC 
GGGGACACCT GGGCCCAGCA GACCTTCCGG GTGGAACACT GGCCCAACGA GACCTCGGTC 
CAGGCCAACG GCAGCTTCGT GCGGGCGACC GTACATGACT ATAGGCTGGT TCTCAACCGG 
AACCTCTCCA TCTCGGAGAA CCGCACCATG CAGCTGGCGG TGCTGGTCAA TGACTCAGAC 
TTCCAGGGCC CAGGAGCGGG CGTCCTCTTG CTCCACTTCA ACGTGTCGGT GCTGCCGGTC 
AGCCTGCACC TGCCCAGTAC CTACTCCCTC TCCGTGAGCA GGAGGGCTCG CCGATTTGCC 
CAGATCGGGA AAGTCTGTGT GGAAAACTGC CAGGCATTCA GTGGCATCAA CGTCCAGTAC 
AAGCTGCATT CCTCTGGTGC CAACTGCAGC ACGCTAGGGG TGGTCACCTC AGCCGAGGAC 
ACCTCGGGGA TCCTGTTTGT GAATGACACC AAGGCCCTGC GGCGGCCCAA GTGTGCCGAA 
CTTCACTACA TGGTGGTGGC CACCGACCAG CAGACCTCTA GGCAGGCCCA GGCCCAGCTG 
CTTGTAACAG TGGAGGGGTC ATATGTGGCC GAGGAGGCGG GCTGCCCCCT GTCCTGTGCA 
GTCAGCAAGA GACGGCTGGA GTGTGAGGAG TGTGGCGGCC TGGGCTCCCC AACAGGCAGG 
TGTGAGTGGA GGCAAGGAGA TGGCAAAGGG ATCACCAGGA ACTTCTCCAC CTGCTCTCCC 
AGCACCAAGA CCTGCCCCGA CGGCCACTGC GATGTTGTGG AGACCCAAGA CATCAACATT 
TGCCCTCAGG ACTGCCTCCG GGGCAGCATT GTTGGGGGAC ACGAGCCTGG GGAGCCCCGG 
GGGATTAAAG CTGGCTATGG CACCTGCAAC TGCTTCCCTG AGGAGGAGAA GTGCTTCTGC 
GAGCCCGAAG ACATCCAGGA TCCACTGTGC GACGAGCTGT GCCGCACGGT GATCGCAGCC 
GCTGTCCTCT TCTCCTTCAT CGTCTCGGTG CTGCTGTCTG CCTTCTGCAT CCACTGCTAC 
CACAAGTTTG CCCACAAGCC ACCCATCTCC TCAGCTGAGA TGACCTTCCG GAGGCCCGCC 
CAGGCCTTCC CGGTCAGCTA CTCCTCTTCC GGTGCCCGCC GGCCCTCGCT GGACTCCATG 
GAGAACCAGG TCTCCGTGGA TGCCTTCAAG ATCCTGGAGG ATCCAAAGTG GGAATTCCCT 
CGGAAGAACT TGGTTCTTGG AAAAACTCTA GGAGAAGGCG AATTTGGAAA AGTGGTCAAG 
GCAACGGCCT TCCATCTGAA AGGCAGAGCA GGGTACACCA CGGTGGCCGT GAAGATGCTG 
AAAGAGAACG CCTCCCCGAG TGAGCTTCGA GACCTGCTGT CAGAGTTCAA CGTCCTGAAG 
CAGGTCAACC ACCCACATGT CATCAAATTG TATGGGGCCT GCAGCCAGGA TGGCCCGCTC 
CTCCTCATCG TGGAGTACGC CAAATACGGC TCCCTGCGGG GCTTCCTCCG CGAGAGCCGC 
AAAGTGGGGC CTGGCTACCT GGGCAGTGGA GGCAGCCGCA ACTCCAGCTC CCTGGACCAC 
CCGGATGAGC GGGCCCTCAC CATGGGCGAC CTCATCTCAT TTGCCTGGCA GATCTCACAG 
GGGATGCAGT ATCTGGCCGA GATGAAGCTC GTTCATCGGG ACTTGGCAGC CAGAAACATC 
CTGGTAGCTG AGGGGCGGAA GATGAAGATT TCGGATTTCG GCTTGTCCCG AGATGTTTAT 
GAAGAGGATT CCTACGTGAA GAGGAGCCAG GGTCGGATTC CAGTTAAATG GATGGCAATT 
GAATCCCTTT TTGATCATAT CTACACCACG CAAAGTGATG TATGGTCTTT TGGTGTCCTG 
CTGTGGGAGA TCGTGACCCT AGGGGGAAAC CCCTATCCTG GGATTCCTCC TGAGCGGCTC 
TTCAACCTTC TGAAGACCGG CCACCGGATG GAGAGGCCAG ACAACTGCAG CGAGGAGATG 
TACCGCCTGA TGCTGCAATG CTGGAAGCAG GAGCCGGACA AAAGGCCGGT GTTTGCGGAC 
ATCAGCAAAG ACCTGGAGAA GATGATGGTT AAGAGGAGAG ACTACTTGGA CCTTGCGGCG 
TCCACTCCAT CTGACTCCCT GATTTATGAC GACGGCCTCT CAGAGGAGGA GACACCGCTG 
GTGGACTGTA ATAATGCCCC CCTCCCTCGA GCCCTCCCTT CCACATGGAT TGAAAACAAA 
CTCTATGGTA GAATTTCCCA TGCATTTACT AGATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065681.1
CDS	191..3409
Translation	MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELVAVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGRISHAFTRF

Target ORF information:

RefSeq Version	NM_020630.4
Organism	Homo sapiens(Human)
Definition	Homo sapiens ret proto-oncogene (RET), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020630.4

ORF Insert Sequence:

ATGGCGAAGG CGACGTCCGG TGCCGCGGGG CTGCGTCTGC TGTTGCTGCT GCTGCTGCCG 
CTGCTAGGCA AAGTGGCATT GGGCCTCTAC TTCTCGAGGG ATGCTTACTG GGAGAAGCTG 
TATGTGGACC AGGCGGCCGG CACGCCCTTG CTGTACGTCC ATGCCCTGCG GGACGCCCCT 
GAGGAGGTGC CCAGCTTCCG CCTGGGCCAG CATCTCTACG GCACGTACCG CACACGGCTG 
CATGAGAACA ACTGGATCTG CATCCAGGAG GACACCGGCC TCCTCTACCT TAACCGGAGC 
CTGGACCATA GCTCCTGGGA GAAGCTCAGT GTCCGCAACC GCGGCTTTCC CCTGCTCACC 
GTCTACCTCA AGGTCTTCCT GTCACCCACA TCCCTTCGTG AGGGCGAGTG CCAGTGGCCA 
GGCTGTGCCC GCGTATACTT CTCCTTCTTC AACACCTCCT TTCCAGCCTG CAGCTCCCTC 
AAGCCCCGGG AGCTCTGCTT CCCAGAGACA AGGCCCTCCT TCCGCATTCG GGAGAACCGA 
CCCCCAGGCA CCTTCCACCA GTTCCGCCTG CTGCCTGTGC AGTTCTTGTG CCCCAACATC 
AGCGTGGCCT ACAGGCTCCT GGAGGGTGAG GGTCTGCCCT TCCGCTGCGC CCCGGACAGC 
CTGGAGGTGA GCACGCGCTG GGCCCTGGAC CGCGAGCAGC GGGAGAAGTA CGAGCTGGTG 
GCCGTGTGCA CCGTGCACGC CGGCGCGCGC GAGGAGGTGG TGATGGTGCC CTTCCCGGTG 
ACCGTGTACG ACGAGGACGA CTCGGCGCCC ACCTTCCCCG CGGGCGTCGA CACCGCCAGC 
GCCGTGGTGG AGTTCAAGCG GAAGGAGGAC ACCGTGGTGG CCACGCTGCG TGTCTTCGAT 
GCAGACGTGG TACCTGCATC AGGGGAGCTG GTGAGGCGGT ACACAAGCAC GCTGCTCCCC 
GGGGACACCT GGGCCCAGCA GACCTTCCGG GTGGAACACT GGCCCAACGA GACCTCGGTC 
CAGGCCAACG GCAGCTTCGT GCGGGCGACC GTACATGACT ATAGGCTGGT TCTCAACCGG 
AACCTCTCCA TCTCGGAGAA CCGCACCATG CAGCTGGCGG TGCTGGTCAA TGACTCAGAC 
TTCCAGGGCC CAGGAGCGGG CGTCCTCTTG CTCCACTTCA ACGTGTCGGT GCTGCCGGTC 
AGCCTGCACC TGCCCAGTAC CTACTCCCTC TCCGTGAGCA GGAGGGCTCG CCGATTTGCC 
CAGATCGGGA AAGTCTGTGT GGAAAACTGC CAGGCATTCA GTGGCATCAA CGTCCAGTAC 
AAGCTGCATT CCTCTGGTGC CAACTGCAGC ACGCTAGGGG TGGTCACCTC AGCCGAGGAC 
ACCTCGGGGA TCCTGTTTGT GAATGACACC AAGGCCCTGC GGCGGCCCAA GTGTGCCGAA 
CTTCACTACA TGGTGGTGGC CACCGACCAG CAGACCTCTA GGCAGGCCCA GGCCCAGCTG 
CTTGTAACAG TGGAGGGGTC ATATGTGGCC GAGGAGGCGG GCTGCCCCCT GTCCTGTGCA 
GTCAGCAAGA GACGGCTGGA GTGTGAGGAG TGTGGCGGCC TGGGCTCCCC AACAGGCAGG 
TGTGAGTGGA GGCAAGGAGA TGGCAAAGGG ATCACCAGGA ACTTCTCCAC CTGCTCTCCC 
AGCACCAAGA CCTGCCCCGA CGGCCACTGC GATGTTGTGG AGACCCAAGA CATCAACATT 
TGCCCTCAGG ACTGCCTCCG GGGCAGCATT GTTGGGGGAC ACGAGCCTGG GGAGCCCCGG 
GGGATTAAAG CTGGCTATGG CACCTGCAAC TGCTTCCCTG AGGAGGAGAA GTGCTTCTGC 
GAGCCCGAAG ACATCCAGGA TCCACTGTGC GACGAGCTGT GCCGCACGGT GATCGCAGCC 
GCTGTCCTCT TCTCCTTCAT CGTCTCGGTG CTGCTGTCTG CCTTCTGCAT CCACTGCTAC 
CACAAGTTTG CCCACAAGCC ACCCATCTCC TCAGCTGAGA TGACCTTCCG GAGGCCCGCC 
CAGGCCTTCC CGGTCAGCTA CTCCTCTTCC GGTGCCCGCC GGCCCTCGCT GGACTCCATG 
GAGAACCAGG TCTCCGTGGA TGCCTTCAAG ATCCTGGAGG ATCCAAAGTG GGAATTCCCT 
CGGAAGAACT TGGTTCTTGG AAAAACTCTA GGAGAAGGCG AATTTGGAAA AGTGGTCAAG 
GCAACGGCCT TCCATCTGAA AGGCAGAGCA GGGTACACCA CGGTGGCCGT GAAGATGCTG 
AAAGAGAACG CCTCCCCGAG TGAGCTTCGA GACCTGCTGT CAGAGTTCAA CGTCCTGAAG 
CAGGTCAACC ACCCACATGT CATCAAATTG TATGGGGCCT GCAGCCAGGA TGGCCCGCTC 
CTCCTCATCG TGGAGTACGC CAAATACGGC TCCCTGCGGG GCTTCCTCCG CGAGAGCCGC 
AAAGTGGGGC CTGGCTACCT GGGCAGTGGA GGCAGCCGCA ACTCCAGCTC CCTGGACCAC 
CCGGATGAGC GGGCCCTCAC CATGGGCGAC CTCATCTCAT TTGCCTGGCA GATCTCACAG 
GGGATGCAGT ATCTGGCCGA GATGAAGCTC GTTCATCGGG ACTTGGCAGC CAGAAACATC 
CTGGTAGCTG AGGGGCGGAA GATGAAGATT TCGGATTTCG GCTTGTCCCG AGATGTTTAT 
GAAGAGGATT CCTACGTGAA GAGGAGCCAG GGTCGGATTC CAGTTAAATG GATGGCAATT 
GAATCCCTTT TTGATCATAT CTACACCACG CAAAGTGATG TATGGTCTTT TGGTGTCCTG 
CTGTGGGAGA TCGTGACCCT AGGGGGAAAC CCCTATCCTG GGATTCCTCC TGAGCGGCTC 
TTCAACCTTC TGAAGACCGG CCACCGGATG GAGAGGCCAG ACAACTGCAG CGAGGAGATG 
TACCGCCTGA TGCTGCAATG CTGGAAGCAG GAGCCGGACA AAAGGCCGGT GTTTGCGGAC 
ATCAGCAAAG ACCTGGAGAA GATGATGGTT AAGAGGAGAG ACTACTTGGA CCTTGCGGCG 
TCCACTCCAT CTGACTCCCT GATTTATGAC GACGGCCTCT CAGAGGAGGA GACACCGCTG 
GTGGACTGTA ATAATGCCCC CCTCCCTCGA GCCCTCCCTT CCACATGGAT TGAAAACAAA 
CTCTATGGTA GAATTTCCCA TGCATTTACT AGATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RET ( NM_020975.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_066124.1 Homo sapiens ret proto-oncogene (RET), transcript variant 2, mRNA.

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CloneID	OHu60238
Clone ID Related Accession (Same CDS sequence)	NM_020975.5 , NM_020975.6
Accession Version	NM_020975.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3345bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	proto-oncogene tyrosine-protein kinase receptor Ret isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA235889.1, AC010864.11, BC003072.2, BC004257.1, X12949.1 and BM661773.1. On Sep 13, 2017 this sequence version replaced NM_020975.4. Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (a). This isoform is also known as Ret51. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAAGG CGACGTCCGG TGCCGCGGGG CTGCGTCTGC TGTTGCTGCT GCTGCTGCCG 
CTGCTAGGCA AAGTGGCATT GGGCCTCTAC TTCTCGAGGG ATGCTTACTG GGAGAAGCTG 
TATGTGGACC AGGCAGCCGG CACGCCCTTG CTGTACGTCC ATGCCCTGCG GGACGCCCCT 
GAGGAGGTGC CCAGCTTCCG CCTGGGCCAG CATCTCTACG GCACGTACCG CACACGGCTG 
CATGAGAACA ACTGGATCTG CATCCAGGAG GACACCGGCC TCCTCTACCT TAACCGGAGC 
CTGGACCATA GCTCCTGGGA GAAGCTCAGT GTCCGCAACC GCGGCTTTCC CCTGCTCACC 
GTCTACCTCA AGGTCTTCCT GTCACCCACA TCCCTTCGTG AGGGCGAGTG CCAGTGGCCA 
GGCTGTGCCC GCGTATACTT CTCCTTCTTC AACACCTCCT TTCCAGCCTG CAGCTCCCTC 
AAGCCCCGGG AGCTCTGCTT CCCAGAGACA AGGCCCTCCT TCCGCATTCG GGAGAACCGA 
CCCCCAGGCA CCTTCCACCA GTTCCGCCTG CTGCCTGTGC AGTTCTTGTG CCCCAACATC 
AGCGTGGCCT ACAGGCTCCT GGAGGGTGAG GGTCTGCCCT TCCGCTGCGC CCCGGACAGC 
CTGGAGGTGA GCACGCGCTG GGCCCTGGAC CGCGAGCAGC GGGAGAAGTA CGAGCTGGTG 
GCCGTGTGCA CCGTGCACGC CGGCGCGCGC GAGGAGGTGG TGATGGTGCC CTTCCCGGTG 
ACCGTGTACG ACGAGGACGA CTCGGCGCCC ACCTTCCCCG CGGGCGTCGA CACCGCCAGC 
GCCGTGGTGG AGTTCAAGCG GAAGGAGGAC ACCGTGGTGG CCACGCTGCG TGTCTTCGAT 
GCAGACGTGG TACCTGCATC AGGGGAGCTG GTGAGGCGGT ACACAAGCAC GCTGCTCCCC 
GGGGACACCT GGGCCCAGCA GACCTTCCGG GTGGAACACT GGCCCAACGA GACCTCGGTC 
CAGGCCAACG GCAGCTTCGT GCGGGCGACC GTACATGACT ATAGGCTGGT TCTCAACCGG 
AACCTCTCCA TCTCGGAGAA CCGCACCATG CAGCTGGCGG TGCTGGTCAA TGACTCAGAC 
TTCCAGGGCC CAGGAGCGGG CGTCCTCTTG CTCCACTTCA ACGTGTCGGT GCTGCCGGTC 
AGCCTGCACC TGCCCAGTAC CTACTCCCTC TCCGTGAGCA GGAGGGCTCG CCGATTTGCC 
CAGATCGGGA AAGTCTGTGT GGAAAACTGC CAGGCATTCA GTGGCATCAA CGTCCAGTAC 
AAGCTGCATT CCTCTGGTGC CAACTGCAGC ACGCTAGGGG TGGTCACCTC AGCCGAGGAC 
ACCTCGGGGA TCCTGTTTGT GAATGACACC AAGGCCCTGC GGCGGCCCAA GTGTGCCGAA 
CTTCACTACA TGGTGGTGGC CACCGACCAG CAGACCTCTA GGCAGGCCCA GGCCCAGCTG 
CTTGTAACAG TGGAGGGGTC ATATGTGGCC GAGGAGGCGG GCTGCCCCCT GTCCTGTGCA 
GTCAGCAAGA GACGGCTGGA GTGTGAGGAG TGTGGCGGCC TGGGCTCCCC AACAGGCAGG 
TGTGAGTGGA GGCAAGGAGA TGGCAAAGGG ATCACCAGGA ACTTCTCCAC CTGCTCTCCC 
AGCACCAAGA CCTGCCCCGA CGGCCACTGC GATGTTGTGG AGACCCAAGA CATCAACATT 
TGCCCTCAGG ACTGCCTCCG GGGCAGCATT GTTGGGGGAC ACGAGCCTGG GGAGCCCCGG 
GGGATTAAAG CTGGCTATGG CACCTGCAAC TGCTTCCCTG AGGAGGAGAA GTGCTTCTGC 
GAGCCCGAAG ACATCCAGGA TCCACTGTGC GACGAGCTGT GCCGCACGGT GATCGCAGCC 
GCTGTCCTCT TCTCCTTCAT CGTCTCGGTG CTGCTGTCTG CCTTCTGCAT CCACTGCTAC 
CACAAGTTTG CCCACAAGCC ACCCATCTCC TCAGCTGAGA TGACCTTCCG GAGGCCCGCC 
CAGGCCTTCC CGGTCAGCTA CTCCTCTTCC GGTGCCCGCC GGCCCTCGCT GGACTCCATG 
GAGAACCAGG TCTCCGTGGA TGCCTTCAAG ATCCTGGAGG ATCCAAAGTG GGAATTCCCT 
CGGAAGAACT TGGTTCTTGG AAAAACTCTA GGAGAAGGCG AATTTGGAAA AGTGGTCAAG 
GCAACGGCCT TCCATCTGAA AGGCAGAGCA GGGTACACCA CGGTGGCCGT GAAGATGCTG 
AAAGAGAACG CCTCCCCGAG TGAGCTGCGA GACCTGCTGT CAGAGTTCAA CGTCCTGAAG 
CAGGTCAACC ACCCACATGT CATCAAATTG TATGGGGCCT GCAGCCAGGA TGGCCCGCTC 
CTCCTCATCG TGGAGTACGC CAAATACGGC TCCCTGCGGG GCTTCCTCCG CGAGAGCCGC 
AAAGTGGGGC CTGGCTACCT GGGCAGTGGA GGCAGCCGCA ACTCCAGCTC CCTGGACCAC 
CCGGATGAGC GGGCCCTCAC CATGGGCGAC CTCATCTCAT TTGCCTGGCA GATCTCACAG 
GGGATGCAGT ATCTGGCCGA GATGAAGCTC GTTCATCGGG ACTTGGCAGC CAGAAACATC 
CTGGTAGCTG AGGGGCGGAA GATGAAGATT TCGGATTTCG GCTTGTCCCG AGATGTTTAT 
GAAGAGGATT CCTACGTGAA GAGGAGCCAG GGTCGGATTC CAGTTAAATG GATGGCAATT 
GAATCCCTTT TTGATCATAT CTACACCACG CAAAGTGATG TATGGTCTTT TGGTGTCCTG 
CTGTGGGAGA TCGTGACCCT AGGGGGAAAC CCCTATCCTG GGATTCCTCC TGAGCGGCTC 
TTCAACCTTC TGAAGACCGG CCACCGGATG GAGAGGCCAG ACAACTGCAG CGAGGAGATG 
TACCGCCTGA TGCTGCAATG CTGGAAGCAG GAGCCGGACA AAAGGCCGGT GTTTGCGGAC 
ATCAGCAAAG ACCTGGAGAA GATGATGGTT AAGAGGAGAG ACTACTTGGA CCTTGCGGCG 
TCCACTCCAT CTGACTCCCT GATTTATGAC GACGGCCTCT CAGAGGAGGA GACACCGCTG 
GTGGACTGTA ATAATGCCCC CCTCCCTCGA GCCCTCCCTT CCACATGGAT TGAAAACAAA 
CTCTATGGCA TGTCAGACCC GAACTGGCCT GGAGAGAGTC CTGTACCACT CACGAGAGCT 
GATGGCACTA ACACTGGGTT TCCAAGATAT CCAAATGATA GTGTATATGC TAACTGGATG 
CTTTCACCCT CAGCGGCAAA ATTAATGGAC ACGTTTGATA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066124.1
CDS	233..3577
Translation	MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELVAVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRYPNDSVYANWMLSPSAAKLMDTFDS

Target ORF information:

RefSeq Version	NM_020975.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ret proto-oncogene (RET), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020975.5

ORF Insert Sequence:

ATGGCGAAGG CGACGTCCGG TGCCGCGGGG CTGCGTCTGC TGTTGCTGCT GCTGCTGCCG 
CTGCTAGGCA AAGTGGCATT GGGCCTCTAC TTCTCGAGGG ATGCTTACTG GGAGAAGCTG 
TATGTGGACC AGGCAGCCGG CACGCCCTTG CTGTACGTCC ATGCCCTGCG GGACGCCCCT 
GAGGAGGTGC CCAGCTTCCG CCTGGGCCAG CATCTCTACG GCACGTACCG CACACGGCTG 
CATGAGAACA ACTGGATCTG CATCCAGGAG GACACCGGCC TCCTCTACCT TAACCGGAGC 
CTGGACCATA GCTCCTGGGA GAAGCTCAGT GTCCGCAACC GCGGCTTTCC CCTGCTCACC 
GTCTACCTCA AGGTCTTCCT GTCACCCACA TCCCTTCGTG AGGGCGAGTG CCAGTGGCCA 
GGCTGTGCCC GCGTATACTT CTCCTTCTTC AACACCTCCT TTCCAGCCTG CAGCTCCCTC 
AAGCCCCGGG AGCTCTGCTT CCCAGAGACA AGGCCCTCCT TCCGCATTCG GGAGAACCGA 
CCCCCAGGCA CCTTCCACCA GTTCCGCCTG CTGCCTGTGC AGTTCTTGTG CCCCAACATC 
AGCGTGGCCT ACAGGCTCCT GGAGGGTGAG GGTCTGCCCT TCCGCTGCGC CCCGGACAGC 
CTGGAGGTGA GCACGCGCTG GGCCCTGGAC CGCGAGCAGC GGGAGAAGTA CGAGCTGGTG 
GCCGTGTGCA CCGTGCACGC CGGCGCGCGC GAGGAGGTGG TGATGGTGCC CTTCCCGGTG 
ACCGTGTACG ACGAGGACGA CTCGGCGCCC ACCTTCCCCG CGGGCGTCGA CACCGCCAGC 
GCCGTGGTGG AGTTCAAGCG GAAGGAGGAC ACCGTGGTGG CCACGCTGCG TGTCTTCGAT 
GCAGACGTGG TACCTGCATC AGGGGAGCTG GTGAGGCGGT ACACAAGCAC GCTGCTCCCC 
GGGGACACCT GGGCCCAGCA GACCTTCCGG GTGGAACACT GGCCCAACGA GACCTCGGTC 
CAGGCCAACG GCAGCTTCGT GCGGGCGACC GTACATGACT ATAGGCTGGT TCTCAACCGG 
AACCTCTCCA TCTCGGAGAA CCGCACCATG CAGCTGGCGG TGCTGGTCAA TGACTCAGAC 
TTCCAGGGCC CAGGAGCGGG CGTCCTCTTG CTCCACTTCA ACGTGTCGGT GCTGCCGGTC 
AGCCTGCACC TGCCCAGTAC CTACTCCCTC TCCGTGAGCA GGAGGGCTCG CCGATTTGCC 
CAGATCGGGA AAGTCTGTGT GGAAAACTGC CAGGCATTCA GTGGCATCAA CGTCCAGTAC 
AAGCTGCATT CCTCTGGTGC CAACTGCAGC ACGCTAGGGG TGGTCACCTC AGCCGAGGAC 
ACCTCGGGGA TCCTGTTTGT GAATGACACC AAGGCCCTGC GGCGGCCCAA GTGTGCCGAA 
CTTCACTACA TGGTGGTGGC CACCGACCAG CAGACCTCTA GGCAGGCCCA GGCCCAGCTG 
CTTGTAACAG TGGAGGGGTC ATATGTGGCC GAGGAGGCGG GCTGCCCCCT GTCCTGTGCA 
GTCAGCAAGA GACGGCTGGA GTGTGAGGAG TGTGGCGGCC TGGGCTCCCC AACAGGCAGG 
TGTGAGTGGA GGCAAGGAGA TGGCAAAGGG ATCACCAGGA ACTTCTCCAC CTGCTCTCCC 
AGCACCAAGA CCTGCCCCGA CGGCCACTGC GATGTTGTGG AGACCCAAGA CATCAACATT 
TGCCCTCAGG ACTGCCTCCG GGGCAGCATT GTTGGGGGAC ACGAGCCTGG GGAGCCCCGG 
GGGATTAAAG CTGGCTATGG CACCTGCAAC TGCTTCCCTG AGGAGGAGAA GTGCTTCTGC 
GAGCCCGAAG ACATCCAGGA TCCACTGTGC GACGAGCTGT GCCGCACGGT GATCGCAGCC 
GCTGTCCTCT TCTCCTTCAT CGTCTCGGTG CTGCTGTCTG CCTTCTGCAT CCACTGCTAC 
CACAAGTTTG CCCACAAGCC ACCCATCTCC TCAGCTGAGA TGACCTTCCG GAGGCCCGCC 
CAGGCCTTCC CGGTCAGCTA CTCCTCTTCC GGTGCCCGCC GGCCCTCGCT GGACTCCATG 
GAGAACCAGG TCTCCGTGGA TGCCTTCAAG ATCCTGGAGG ATCCAAAGTG GGAATTCCCT 
CGGAAGAACT TGGTTCTTGG AAAAACTCTA GGAGAAGGCG AATTTGGAAA AGTGGTCAAG 
GCAACGGCCT TCCATCTGAA AGGCAGAGCA GGGTACACCA CGGTGGCCGT GAAGATGCTG 
AAAGAGAACG CCTCCCCGAG TGAGCTGCGA GACCTGCTGT CAGAGTTCAA CGTCCTGAAG 
CAGGTCAACC ACCCACATGT CATCAAATTG TATGGGGCCT GCAGCCAGGA TGGCCCGCTC 
CTCCTCATCG TGGAGTACGC CAAATACGGC TCCCTGCGGG GCTTCCTCCG CGAGAGCCGC 
AAAGTGGGGC CTGGCTACCT GGGCAGTGGA GGCAGCCGCA ACTCCAGCTC CCTGGACCAC 
CCGGATGAGC GGGCCCTCAC CATGGGCGAC CTCATCTCAT TTGCCTGGCA GATCTCACAG 
GGGATGCAGT ATCTGGCCGA GATGAAGCTC GTTCATCGGG ACTTGGCAGC CAGAAACATC 
CTGGTAGCTG AGGGGCGGAA GATGAAGATT TCGGATTTCG GCTTGTCCCG AGATGTTTAT 
GAAGAGGATT CCTACGTGAA GAGGAGCCAG GGTCGGATTC CAGTTAAATG GATGGCAATT 
GAATCCCTTT TTGATCATAT CTACACCACG CAAAGTGATG TATGGTCTTT TGGTGTCCTG 
CTGTGGGAGA TCGTGACCCT AGGGGGAAAC CCCTATCCTG GGATTCCTCC TGAGCGGCTC 
TTCAACCTTC TGAAGACCGG CCACCGGATG GAGAGGCCAG ACAACTGCAG CGAGGAGATG 
TACCGCCTGA TGCTGCAATG CTGGAAGCAG GAGCCGGACA AAAGGCCGGT GTTTGCGGAC 
ATCAGCAAAG ACCTGGAGAA GATGATGGTT AAGAGGAGAG ACTACTTGGA CCTTGCGGCG 
TCCACTCCAT CTGACTCCCT GATTTATGAC GACGGCCTCT CAGAGGAGGA GACACCGCTG 
GTGGACTGTA ATAATGCCCC CCTCCCTCGA GCCCTCCCTT CCACATGGAT TGAAAACAAA 
CTCTATGGCA TGTCAGACCC GAACTGGCCT GGAGAGAGTC CTGTACCACT CACGAGAGCT 
GATGGCACTA ACACTGGGTT TCCAAGATAT CCAAATGATA GTGTATATGC TAACTGGATG 
CTTTCACCCT CAGCGGCAAA ATTAATGGAC ACGTTTGATA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RET ( NM_020975.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_066124.1 Homo sapiens ret proto-oncogene (RET), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu60238
Clone ID Related Accession (Same CDS sequence)	NM_020975.5 , NM_020975.6
Accession Version	NM_020975.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3345bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	proto-oncogene tyrosine-protein kinase receptor Ret isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC010864.11, BC003072.2, BC004257.1, X12949.1 and BM661773.1. On Nov 23, 2018 this sequence version replaced NM_020975.5. Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (a). This isoform is also known as Ret51. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000355710.8/ ENSP00000347942.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGAAGG CGACGTCCGG TGCCGCGGGG CTGCGTCTGC TGTTGCTGCT GCTGCTGCCG 
CTGCTAGGCA AAGTGGCATT GGGCCTCTAC TTCTCGAGGG ATGCTTACTG GGAGAAGCTG 
TATGTGGACC AGGCAGCCGG CACGCCCTTG CTGTACGTCC ATGCCCTGCG GGACGCCCCT 
GAGGAGGTGC CCAGCTTCCG CCTGGGCCAG CATCTCTACG GCACGTACCG CACACGGCTG 
CATGAGAACA ACTGGATCTG CATCCAGGAG GACACCGGCC TCCTCTACCT TAACCGGAGC 
CTGGACCATA GCTCCTGGGA GAAGCTCAGT GTCCGCAACC GCGGCTTTCC CCTGCTCACC 
GTCTACCTCA AGGTCTTCCT GTCACCCACA TCCCTTCGTG AGGGCGAGTG CCAGTGGCCA 
GGCTGTGCCC GCGTATACTT CTCCTTCTTC AACACCTCCT TTCCAGCCTG CAGCTCCCTC 
AAGCCCCGGG AGCTCTGCTT CCCAGAGACA AGGCCCTCCT TCCGCATTCG GGAGAACCGA 
CCCCCAGGCA CCTTCCACCA GTTCCGCCTG CTGCCTGTGC AGTTCTTGTG CCCCAACATC 
AGCGTGGCCT ACAGGCTCCT GGAGGGTGAG GGTCTGCCCT TCCGCTGCGC CCCGGACAGC 
CTGGAGGTGA GCACGCGCTG GGCCCTGGAC CGCGAGCAGC GGGAGAAGTA CGAGCTGGTG 
GCCGTGTGCA CCGTGCACGC CGGCGCGCGC GAGGAGGTGG TGATGGTGCC CTTCCCGGTG 
ACCGTGTACG ACGAGGACGA CTCGGCGCCC ACCTTCCCCG CGGGCGTCGA CACCGCCAGC 
GCCGTGGTGG AGTTCAAGCG GAAGGAGGAC ACCGTGGTGG CCACGCTGCG TGTCTTCGAT 
GCAGACGTGG TACCTGCATC AGGGGAGCTG GTGAGGCGGT ACACAAGCAC GCTGCTCCCC 
GGGGACACCT GGGCCCAGCA GACCTTCCGG GTGGAACACT GGCCCAACGA GACCTCGGTC 
CAGGCCAACG GCAGCTTCGT GCGGGCGACC GTACATGACT ATAGGCTGGT TCTCAACCGG 
AACCTCTCCA TCTCGGAGAA CCGCACCATG CAGCTGGCGG TGCTGGTCAA TGACTCAGAC 
TTCCAGGGCC CAGGAGCGGG CGTCCTCTTG CTCCACTTCA ACGTGTCGGT GCTGCCGGTC 
AGCCTGCACC TGCCCAGTAC CTACTCCCTC TCCGTGAGCA GGAGGGCTCG CCGATTTGCC 
CAGATCGGGA AAGTCTGTGT GGAAAACTGC CAGGCATTCA GTGGCATCAA CGTCCAGTAC 
AAGCTGCATT CCTCTGGTGC CAACTGCAGC ACGCTAGGGG TGGTCACCTC AGCCGAGGAC 
ACCTCGGGGA TCCTGTTTGT GAATGACACC AAGGCCCTGC GGCGGCCCAA GTGTGCCGAA 
CTTCACTACA TGGTGGTGGC CACCGACCAG CAGACCTCTA GGCAGGCCCA GGCCCAGCTG 
CTTGTAACAG TGGAGGGGTC ATATGTGGCC GAGGAGGCGG GCTGCCCCCT GTCCTGTGCA 
GTCAGCAAGA GACGGCTGGA GTGTGAGGAG TGTGGCGGCC TGGGCTCCCC AACAGGCAGG 
TGTGAGTGGA GGCAAGGAGA TGGCAAAGGG ATCACCAGGA ACTTCTCCAC CTGCTCTCCC 
AGCACCAAGA CCTGCCCCGA CGGCCACTGC GATGTTGTGG AGACCCAAGA CATCAACATT 
TGCCCTCAGG ACTGCCTCCG GGGCAGCATT GTTGGGGGAC ACGAGCCTGG GGAGCCCCGG 
GGGATTAAAG CTGGCTATGG CACCTGCAAC TGCTTCCCTG AGGAGGAGAA GTGCTTCTGC 
GAGCCCGAAG ACATCCAGGA TCCACTGTGC GACGAGCTGT GCCGCACGGT GATCGCAGCC 
GCTGTCCTCT TCTCCTTCAT CGTCTCGGTG CTGCTGTCTG CCTTCTGCAT CCACTGCTAC 
CACAAGTTTG CCCACAAGCC ACCCATCTCC TCAGCTGAGA TGACCTTCCG GAGGCCCGCC 
CAGGCCTTCC CGGTCAGCTA CTCCTCTTCC GGTGCCCGCC GGCCCTCGCT GGACTCCATG 
GAGAACCAGG TCTCCGTGGA TGCCTTCAAG ATCCTGGAGG ATCCAAAGTG GGAATTCCCT 
CGGAAGAACT TGGTTCTTGG AAAAACTCTA GGAGAAGGCG AATTTGGAAA AGTGGTCAAG 
GCAACGGCCT TCCATCTGAA AGGCAGAGCA GGGTACACCA CGGTGGCCGT GAAGATGCTG 
AAAGAGAACG CCTCCCCGAG TGAGCTGCGA GACCTGCTGT CAGAGTTCAA CGTCCTGAAG 
CAGGTCAACC ACCCACATGT CATCAAATTG TATGGGGCCT GCAGCCAGGA TGGCCCGCTC 
CTCCTCATCG TGGAGTACGC CAAATACGGC TCCCTGCGGG GCTTCCTCCG CGAGAGCCGC 
AAAGTGGGGC CTGGCTACCT GGGCAGTGGA GGCAGCCGCA ACTCCAGCTC CCTGGACCAC 
CCGGATGAGC GGGCCCTCAC CATGGGCGAC CTCATCTCAT TTGCCTGGCA GATCTCACAG 
GGGATGCAGT ATCTGGCCGA GATGAAGCTC GTTCATCGGG ACTTGGCAGC CAGAAACATC 
CTGGTAGCTG AGGGGCGGAA GATGAAGATT TCGGATTTCG GCTTGTCCCG AGATGTTTAT 
GAAGAGGATT CCTACGTGAA GAGGAGCCAG GGTCGGATTC CAGTTAAATG GATGGCAATT 
GAATCCCTTT TTGATCATAT CTACACCACG CAAAGTGATG TATGGTCTTT TGGTGTCCTG 
CTGTGGGAGA TCGTGACCCT AGGGGGAAAC CCCTATCCTG GGATTCCTCC TGAGCGGCTC 
TTCAACCTTC TGAAGACCGG CCACCGGATG GAGAGGCCAG ACAACTGCAG CGAGGAGATG 
TACCGCCTGA TGCTGCAATG CTGGAAGCAG GAGCCGGACA AAAGGCCGGT GTTTGCGGAC 
ATCAGCAAAG ACCTGGAGAA GATGATGGTT AAGAGGAGAG ACTACTTGGA CCTTGCGGCG 
TCCACTCCAT CTGACTCCCT GATTTATGAC GACGGCCTCT CAGAGGAGGA GACACCGCTG 
GTGGACTGTA ATAATGCCCC CCTCCCTCGA GCCCTCCCTT CCACATGGAT TGAAAACAAA 
CTCTATGGCA TGTCAGACCC GAACTGGCCT GGAGAGAGTC CTGTACCACT CACGAGAGCT 
GATGGCACTA ACACTGGGTT TCCAAGATAT CCAAATGATA GTGTATATGC TAACTGGATG 
CTTTCACCCT CAGCGGCAAA ATTAATGGAC ACGTTTGATA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066124.1
CDS	191..3535
Translation	MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELVAVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRYPNDSVYANWMLSPSAAKLMDTFDS

Target ORF information:

RefSeq Version	NM_020975.6
Organism	Homo sapiens(human)
Definition	Homo sapiens ret proto-oncogene (RET), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020975.6

ORF Insert Sequence:

ATGGCGAAGG CGACGTCCGG TGCCGCGGGG CTGCGTCTGC TGTTGCTGCT GCTGCTGCCG 
CTGCTAGGCA AAGTGGCATT GGGCCTCTAC TTCTCGAGGG ATGCTTACTG GGAGAAGCTG 
TATGTGGACC AGGCAGCCGG CACGCCCTTG CTGTACGTCC ATGCCCTGCG GGACGCCCCT 
GAGGAGGTGC CCAGCTTCCG CCTGGGCCAG CATCTCTACG GCACGTACCG CACACGGCTG 
CATGAGAACA ACTGGATCTG CATCCAGGAG GACACCGGCC TCCTCTACCT TAACCGGAGC 
CTGGACCATA GCTCCTGGGA GAAGCTCAGT GTCCGCAACC GCGGCTTTCC CCTGCTCACC 
GTCTACCTCA AGGTCTTCCT GTCACCCACA TCCCTTCGTG AGGGCGAGTG CCAGTGGCCA 
GGCTGTGCCC GCGTATACTT CTCCTTCTTC AACACCTCCT TTCCAGCCTG CAGCTCCCTC 
AAGCCCCGGG AGCTCTGCTT CCCAGAGACA AGGCCCTCCT TCCGCATTCG GGAGAACCGA 
CCCCCAGGCA CCTTCCACCA GTTCCGCCTG CTGCCTGTGC AGTTCTTGTG CCCCAACATC 
AGCGTGGCCT ACAGGCTCCT GGAGGGTGAG GGTCTGCCCT TCCGCTGCGC CCCGGACAGC 
CTGGAGGTGA GCACGCGCTG GGCCCTGGAC CGCGAGCAGC GGGAGAAGTA CGAGCTGGTG 
GCCGTGTGCA CCGTGCACGC CGGCGCGCGC GAGGAGGTGG TGATGGTGCC CTTCCCGGTG 
ACCGTGTACG ACGAGGACGA CTCGGCGCCC ACCTTCCCCG CGGGCGTCGA CACCGCCAGC 
GCCGTGGTGG AGTTCAAGCG GAAGGAGGAC ACCGTGGTGG CCACGCTGCG TGTCTTCGAT 
GCAGACGTGG TACCTGCATC AGGGGAGCTG GTGAGGCGGT ACACAAGCAC GCTGCTCCCC 
GGGGACACCT GGGCCCAGCA GACCTTCCGG GTGGAACACT GGCCCAACGA GACCTCGGTC 
CAGGCCAACG GCAGCTTCGT GCGGGCGACC GTACATGACT ATAGGCTGGT TCTCAACCGG 
AACCTCTCCA TCTCGGAGAA CCGCACCATG CAGCTGGCGG TGCTGGTCAA TGACTCAGAC 
TTCCAGGGCC CAGGAGCGGG CGTCCTCTTG CTCCACTTCA ACGTGTCGGT GCTGCCGGTC 
AGCCTGCACC TGCCCAGTAC CTACTCCCTC TCCGTGAGCA GGAGGGCTCG CCGATTTGCC 
CAGATCGGGA AAGTCTGTGT GGAAAACTGC CAGGCATTCA GTGGCATCAA CGTCCAGTAC 
AAGCTGCATT CCTCTGGTGC CAACTGCAGC ACGCTAGGGG TGGTCACCTC AGCCGAGGAC 
ACCTCGGGGA TCCTGTTTGT GAATGACACC AAGGCCCTGC GGCGGCCCAA GTGTGCCGAA 
CTTCACTACA TGGTGGTGGC CACCGACCAG CAGACCTCTA GGCAGGCCCA GGCCCAGCTG 
CTTGTAACAG TGGAGGGGTC ATATGTGGCC GAGGAGGCGG GCTGCCCCCT GTCCTGTGCA 
GTCAGCAAGA GACGGCTGGA GTGTGAGGAG TGTGGCGGCC TGGGCTCCCC AACAGGCAGG 
TGTGAGTGGA GGCAAGGAGA TGGCAAAGGG ATCACCAGGA ACTTCTCCAC CTGCTCTCCC 
AGCACCAAGA CCTGCCCCGA CGGCCACTGC GATGTTGTGG AGACCCAAGA CATCAACATT 
TGCCCTCAGG ACTGCCTCCG GGGCAGCATT GTTGGGGGAC ACGAGCCTGG GGAGCCCCGG 
GGGATTAAAG CTGGCTATGG CACCTGCAAC TGCTTCCCTG AGGAGGAGAA GTGCTTCTGC 
GAGCCCGAAG ACATCCAGGA TCCACTGTGC GACGAGCTGT GCCGCACGGT GATCGCAGCC 
GCTGTCCTCT TCTCCTTCAT CGTCTCGGTG CTGCTGTCTG CCTTCTGCAT CCACTGCTAC 
CACAAGTTTG CCCACAAGCC ACCCATCTCC TCAGCTGAGA TGACCTTCCG GAGGCCCGCC 
CAGGCCTTCC CGGTCAGCTA CTCCTCTTCC GGTGCCCGCC GGCCCTCGCT GGACTCCATG 
GAGAACCAGG TCTCCGTGGA TGCCTTCAAG ATCCTGGAGG ATCCAAAGTG GGAATTCCCT 
CGGAAGAACT TGGTTCTTGG AAAAACTCTA GGAGAAGGCG AATTTGGAAA AGTGGTCAAG 
GCAACGGCCT TCCATCTGAA AGGCAGAGCA GGGTACACCA CGGTGGCCGT GAAGATGCTG 
AAAGAGAACG CCTCCCCGAG TGAGCTGCGA GACCTGCTGT CAGAGTTCAA CGTCCTGAAG 
CAGGTCAACC ACCCACATGT CATCAAATTG TATGGGGCCT GCAGCCAGGA TGGCCCGCTC 
CTCCTCATCG TGGAGTACGC CAAATACGGC TCCCTGCGGG GCTTCCTCCG CGAGAGCCGC 
AAAGTGGGGC CTGGCTACCT GGGCAGTGGA GGCAGCCGCA ACTCCAGCTC CCTGGACCAC 
CCGGATGAGC GGGCCCTCAC CATGGGCGAC CTCATCTCAT TTGCCTGGCA GATCTCACAG 
GGGATGCAGT ATCTGGCCGA GATGAAGCTC GTTCATCGGG ACTTGGCAGC CAGAAACATC 
CTGGTAGCTG AGGGGCGGAA GATGAAGATT TCGGATTTCG GCTTGTCCCG AGATGTTTAT 
GAAGAGGATT CCTACGTGAA GAGGAGCCAG GGTCGGATTC CAGTTAAATG GATGGCAATT 
GAATCCCTTT TTGATCATAT CTACACCACG CAAAGTGATG TATGGTCTTT TGGTGTCCTG 
CTGTGGGAGA TCGTGACCCT AGGGGGAAAC CCCTATCCTG GGATTCCTCC TGAGCGGCTC 
TTCAACCTTC TGAAGACCGG CCACCGGATG GAGAGGCCAG ACAACTGCAG CGAGGAGATG 
TACCGCCTGA TGCTGCAATG CTGGAAGCAG GAGCCGGACA AAAGGCCGGT GTTTGCGGAC 
ATCAGCAAAG ACCTGGAGAA GATGATGGTT AAGAGGAGAG ACTACTTGGA CCTTGCGGCG 
TCCACTCCAT CTGACTCCCT GATTTATGAC GACGGCCTCT CAGAGGAGGA GACACCGCTG 
GTGGACTGTA ATAATGCCCC CCTCCCTCGA GCCCTCCCTT CCACATGGAT TGAAAACAAA 
CTCTATGGCA TGTCAGACCC GAACTGGCCT GGAGAGAGTC CTGTACCACT CACGAGAGCT 
GATGGCACTA ACACTGGGTT TCCAAGATAT CCAAATGATA GTGTATATGC TAACTGGATG 
CTTTCACCCT CAGCGGCAAA ATTAATGGAC ACGTTTGATA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RET ( NM_001355216.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001342145.1 Homo sapiens ret proto-oncogene (RET), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu102961
Clone ID Related Accession (Same CDS sequence)	NM_001355216.1
Accession Version	NM_001355216.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2457bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Homo sapiens(human)
Product	proto-oncogene tyrosine-protein kinase receptor Ret isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC351179.1, AC010864.11, AK294827.1 and BC004257.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294827.1, SRR1803614.181438.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCCCT TCCCGGTGAC CGTGTACGAC GAGGACGACT CGGCGCCCAC CTTCCCCGCG 
GGCGTCGACA CCGCCAGCGC CGTGGTGGAG TTCAAGCGGA AGGAGGACAC CGTGGTGGCC 
ACGCTGCGTG TCTTCGATGC AGACGTGGTA CCTGCATCAG GGGAGCTGGT GAGGCGGTAC 
ACAAGCACGC TGCTCCCCGG GGACACCTGG GCCCAGCAGA CCTTCCGGGT GGAACACTGG 
CCCAACGAGA CCTCGGTCCA GGCCAACGGC AGCTTCGTGC GGGCGACCGT ACATGACTAT 
AGGCTGGTTC TCAACCGGAA CCTCTCCATC TCGGAGAACC GCACCATGCA GCTGGCGGTG 
CTGGTCAATG ACTCAGACTT CCAGGGCCCA GGAGCGGGCG TCCTCTTGCT CCACTTCAAC 
GTGTCGGTGC TGCCGGTCAG CCTGCACCTG CCCAGTACCT ACTCCCTCTC CGTGAGCAGG 
AGGGCTCGCC GATTTGCCCA GATCGGGAAA GTCTGTGTGG AAAACTGCCA GGCATTCAGT 
GGCATCAACG TCCAGTACAA GCTGCATTCC TCTGGTGCCA ACTGCAGCAC GCTAGGGGTG 
GTCACCTCAG CCGAGGACAC CTCGGGGATC CTGTTTGTGA ATGACACCAA GGCCCTGCGG 
CGGCCCAAGT GTGCCGAACT TCACTACATG GTGGTGGCCA CCGACCAGCA GACCTCTAGG 
CAGGCCCAGG CCCAGCTGCT TGTAACAGTG GAGGGGTCAT ATGTGGCCGA GGAGGCGGGC 
TGCCCCCTGT CCTGTGCAGT CAGCAAGAGA CGGCTGGAGT GTGAGGAGTG TGGCGGCCTG 
GGCTCCCCAA CAGGCAGGTG TGAGTGGAGG CAAGGAGATG GCAAAGGGAT CACCAGGAAC 
TTCTCCACCT GCTCTCCCAG CACCAAGACC TGCCCCGACG GCCACTGCGA TGTTGTGGAG 
ACCCAAGACA TCAACATTTG CCCTCAGGAC TGCCTCCGGG GCAGCATTGT TGGGGGACAC 
GAGCCTGGGG AGCCCCGGGG GATTAAAGCT GGCTATGGCA CCTGCAACTG CTTCCCTGAG 
GAGGAGAAGT GCTTCTGCGA GCCCGAAGAC ATCCAGGATC CACTGTGCGA CGAGCTGTGC 
CGCACGGTGA TCGCAGCCGC TGTCCTCTTC TCCTTCATCG TCTCGGTGCT GCTGTCTGCC 
TTCTGCATCC ACTGCTACCA CAAGTTTGCC CACAAGCCAC CCATCTCCTC AGCTGAGATG 
ACCTTCCGGA GGCCCGCCCA GGCCTTCCCG GTCAGCTACT CCTCTTCCGG TGCCCGCCGG 
CCCTCGCTGG ACTCCATGGA GAACCAGGTC TCCGTGGATG CCTTCAAGAT CCTGGAGGAT 
CCAAAGTGGG AATTCCCTCG GAAGAACTTG GTTCTTGGAA AAACTCTAGG AGAAGGCGAA 
TTTGGAAAAG TGGTCAAGGC AACGGCCTTC CATCTGAAAG GCAGAGCAGG GTACACCACG 
GTGGCCGTGA AGATGCTGAA AGAGAACGCC TCCCCGAGTG AGCTGCGAGA CCTGCTGTCA 
GAGTTCAACG TCCTGAAGCA GGTCAACCAC CCACATGTCA TCAAATTGTA TGGGGCCTGC 
AGCCAGGATG GCCCGCTCCT CCTCATCGTG GAGTACGCCA AATACGGCTC CCTGCGGGGC 
TTCCTCCGCG AGAGCCGCAA AGTGGGGCCT GGCTACCTGG GCAGTGGAGG CAGCCGCAAC 
TCCAGCTCCC TGGACCACCC GGATGAGCGG GCCCTCACCA TGGGCGACCT CATCTCATTT 
GCCTGGCAGA TCTCACAGGG GATGCAGTAT CTGGCCGAGA TGAAGCTCGT TCATCGGGAC 
TTGGCAGCCA GAAACATCCT GGTAGCTGAG GGGCGGAAGA TGAAGATTTC GGATTTCGGC 
TTGTCCCGAG ATGTTTATGA AGAGGATTCC TACGTGAAGA GGAGCCAGGG TCGGATTCCA 
GTTAAATGGA TGGCAATTGA ATCCCTTTTT GATCATATCT ACACCACGCA AAGTGATGTA 
TGGTCTTTTG GTGTCCTGCT GTGGGAGATC GTGACCCTAG GGGGAAACCC CTATCCTGGG 
ATTCCTCCTG AGCGGCTCTT CAACCTTCTG AAGACCGGCC ACCGGATGGA GAGGCCAGAC 
AACTGCAGCG AGGAGATGTA CCGCCTGATG CTGCAATGCT GGAAGCAGGA GCCGGACAAA 
AGGCCGGTGT TTGCGGACAT CAGCAAAGAC CTGGAGAAGA TGATGGTTAA GAGGAGAGAC 
TACTTGGACC TTGCGGCGTC CACTCCATCT GACTCCCTGA TTTATGACGA CGGCCTCTCA 
GAGGAGGAGA CACCGCTGGT GGACTGTAAT AATGCCCCCC TCCCTCGAGC CCTCCCTTCC 
ACATGGATTG AAAACAAACT CTATGGTAGA ATTTCCCATG CATTTACTAG ATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001342145.1
CDS	358..2814
Translation	MVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGRISHAFTRF

Target ORF information:

RefSeq Version	NM_001355216.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ret proto-oncogene (RET), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001355216.1

ORF Insert Sequence:

ATGGTGCCCT TCCCGGTGAC CGTGTACGAC GAGGACGACT CGGCGCCCAC CTTCCCCGCG 
GGCGTCGACA CCGCCAGCGC CGTGGTGGAG TTCAAGCGGA AGGAGGACAC CGTGGTGGCC 
ACGCTGCGTG TCTTCGATGC AGACGTGGTA CCTGCATCAG GGGAGCTGGT GAGGCGGTAC 
ACAAGCACGC TGCTCCCCGG GGACACCTGG GCCCAGCAGA CCTTCCGGGT GGAACACTGG 
CCCAACGAGA CCTCGGTCCA GGCCAACGGC AGCTTCGTGC GGGCGACCGT ACATGACTAT 
AGGCTGGTTC TCAACCGGAA CCTCTCCATC TCGGAGAACC GCACCATGCA GCTGGCGGTG 
CTGGTCAATG ACTCAGACTT CCAGGGCCCA GGAGCGGGCG TCCTCTTGCT CCACTTCAAC 
GTGTCGGTGC TGCCGGTCAG CCTGCACCTG CCCAGTACCT ACTCCCTCTC CGTGAGCAGG 
AGGGCTCGCC GATTTGCCCA GATCGGGAAA GTCTGTGTGG AAAACTGCCA GGCATTCAGT 
GGCATCAACG TCCAGTACAA GCTGCATTCC TCTGGTGCCA ACTGCAGCAC GCTAGGGGTG 
GTCACCTCAG CCGAGGACAC CTCGGGGATC CTGTTTGTGA ATGACACCAA GGCCCTGCGG 
CGGCCCAAGT GTGCCGAACT TCACTACATG GTGGTGGCCA CCGACCAGCA GACCTCTAGG 
CAGGCCCAGG CCCAGCTGCT TGTAACAGTG GAGGGGTCAT ATGTGGCCGA GGAGGCGGGC 
TGCCCCCTGT CCTGTGCAGT CAGCAAGAGA CGGCTGGAGT GTGAGGAGTG TGGCGGCCTG 
GGCTCCCCAA CAGGCAGGTG TGAGTGGAGG CAAGGAGATG GCAAAGGGAT CACCAGGAAC 
TTCTCCACCT GCTCTCCCAG CACCAAGACC TGCCCCGACG GCCACTGCGA TGTTGTGGAG 
ACCCAAGACA TCAACATTTG CCCTCAGGAC TGCCTCCGGG GCAGCATTGT TGGGGGACAC 
GAGCCTGGGG AGCCCCGGGG GATTAAAGCT GGCTATGGCA CCTGCAACTG CTTCCCTGAG 
GAGGAGAAGT GCTTCTGCGA GCCCGAAGAC ATCCAGGATC CACTGTGCGA CGAGCTGTGC 
CGCACGGTGA TCGCAGCCGC TGTCCTCTTC TCCTTCATCG TCTCGGTGCT GCTGTCTGCC 
TTCTGCATCC ACTGCTACCA CAAGTTTGCC CACAAGCCAC CCATCTCCTC AGCTGAGATG 
ACCTTCCGGA GGCCCGCCCA GGCCTTCCCG GTCAGCTACT CCTCTTCCGG TGCCCGCCGG 
CCCTCGCTGG ACTCCATGGA GAACCAGGTC TCCGTGGATG CCTTCAAGAT CCTGGAGGAT 
CCAAAGTGGG AATTCCCTCG GAAGAACTTG GTTCTTGGAA AAACTCTAGG AGAAGGCGAA 
TTTGGAAAAG TGGTCAAGGC AACGGCCTTC CATCTGAAAG GCAGAGCAGG GTACACCACG 
GTGGCCGTGA AGATGCTGAA AGAGAACGCC TCCCCGAGTG AGCTGCGAGA CCTGCTGTCA 
GAGTTCAACG TCCTGAAGCA GGTCAACCAC CCACATGTCA TCAAATTGTA TGGGGCCTGC 
AGCCAGGATG GCCCGCTCCT CCTCATCGTG GAGTACGCCA AATACGGCTC CCTGCGGGGC 
TTCCTCCGCG AGAGCCGCAA AGTGGGGCCT GGCTACCTGG GCAGTGGAGG CAGCCGCAAC 
TCCAGCTCCC TGGACCACCC GGATGAGCGG GCCCTCACCA TGGGCGACCT CATCTCATTT 
GCCTGGCAGA TCTCACAGGG GATGCAGTAT CTGGCCGAGA TGAAGCTCGT TCATCGGGAC 
TTGGCAGCCA GAAACATCCT GGTAGCTGAG GGGCGGAAGA TGAAGATTTC GGATTTCGGC 
TTGTCCCGAG ATGTTTATGA AGAGGATTCC TACGTGAAGA GGAGCCAGGG TCGGATTCCA 
GTTAAATGGA TGGCAATTGA ATCCCTTTTT GATCATATCT ACACCACGCA AAGTGATGTA 
TGGTCTTTTG GTGTCCTGCT GTGGGAGATC GTGACCCTAG GGGGAAACCC CTATCCTGGG 
ATTCCTCCTG AGCGGCTCTT CAACCTTCTG AAGACCGGCC ACCGGATGGA GAGGCCAGAC 
AACTGCAGCG AGGAGATGTA CCGCCTGATG CTGCAATGCT GGAAGCAGGA GCCGGACAAA 
AGGCCGGTGT TTGCGGACAT CAGCAAAGAC CTGGAGAAGA TGATGGTTAA GAGGAGAGAC 
TACTTGGACC TTGCGGCGTC CACTCCATCT GACTCCCTGA TTTATGACGA CGGCCTCTCA 
GAGGAGGAGA CACCGCTGGT GGACTGTAAT AATGCCCCCC TCCCTCGAGC CCTCCCTTCC 
ACATGGATTG AAAACAAACT CTATGGTAGA ATTTCCCATG CATTTACTAG ATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RET ( NM_020630.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_065681.1 Homo sapiens ret proto-oncogene (RET), transcript variant 4, mRNA.

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CloneID	OHu102970
Clone ID Related Accession (Same CDS sequence)	NM_020630.5
Accession Version	NM_020630.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3219bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	proto-oncogene tyrosine-protein kinase receptor Ret isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA235889.1, AC010864.11, BC004257.1 and AK294827.1. On Sep 13, 2017 this sequence version replaced NM_020630.4. Transcript Variant: This variant (4) differs in the 3' UTR and coding region compared to variant 2. The resulting isoform (c) is shorter and has a distinct C-terminus compared to isoform a. This isoform is also known as Ret9. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC004257.1, SRR1803617.37059.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAAGG CGACGTCCGG TGCCGCGGGG CTGCGTCTGC TGTTGCTGCT GCTGCTGCCG 
CTGCTAGGCA AAGTGGCATT GGGCCTCTAC TTCTCGAGGG ATGCTTACTG GGAGAAGCTG 
TATGTGGACC AGGCAGCCGG CACGCCCTTG CTGTACGTCC ATGCCCTGCG GGACGCCCCT 
GAGGAGGTGC CCAGCTTCCG CCTGGGCCAG CATCTCTACG GCACGTACCG CACACGGCTG 
CATGAGAACA ACTGGATCTG CATCCAGGAG GACACCGGCC TCCTCTACCT TAACCGGAGC 
CTGGACCATA GCTCCTGGGA GAAGCTCAGT GTCCGCAACC GCGGCTTTCC CCTGCTCACC 
GTCTACCTCA AGGTCTTCCT GTCACCCACA TCCCTTCGTG AGGGCGAGTG CCAGTGGCCA 
GGCTGTGCCC GCGTATACTT CTCCTTCTTC AACACCTCCT TTCCAGCCTG CAGCTCCCTC 
AAGCCCCGGG AGCTCTGCTT CCCAGAGACA AGGCCCTCCT TCCGCATTCG GGAGAACCGA 
CCCCCAGGCA CCTTCCACCA GTTCCGCCTG CTGCCTGTGC AGTTCTTGTG CCCCAACATC 
AGCGTGGCCT ACAGGCTCCT GGAGGGTGAG GGTCTGCCCT TCCGCTGCGC CCCGGACAGC 
CTGGAGGTGA GCACGCGCTG GGCCCTGGAC CGCGAGCAGC GGGAGAAGTA CGAGCTGGTG 
GCCGTGTGCA CCGTGCACGC CGGCGCGCGC GAGGAGGTGG TGATGGTGCC CTTCCCGGTG 
ACCGTGTACG ACGAGGACGA CTCGGCGCCC ACCTTCCCCG CGGGCGTCGA CACCGCCAGC 
GCCGTGGTGG AGTTCAAGCG GAAGGAGGAC ACCGTGGTGG CCACGCTGCG TGTCTTCGAT 
GCAGACGTGG TACCTGCATC AGGGGAGCTG GTGAGGCGGT ACACAAGCAC GCTGCTCCCC 
GGGGACACCT GGGCCCAGCA GACCTTCCGG GTGGAACACT GGCCCAACGA GACCTCGGTC 
CAGGCCAACG GCAGCTTCGT GCGGGCGACC GTACATGACT ATAGGCTGGT TCTCAACCGG 
AACCTCTCCA TCTCGGAGAA CCGCACCATG CAGCTGGCGG TGCTGGTCAA TGACTCAGAC 
TTCCAGGGCC CAGGAGCGGG CGTCCTCTTG CTCCACTTCA ACGTGTCGGT GCTGCCGGTC 
AGCCTGCACC TGCCCAGTAC CTACTCCCTC TCCGTGAGCA GGAGGGCTCG CCGATTTGCC 
CAGATCGGGA AAGTCTGTGT GGAAAACTGC CAGGCATTCA GTGGCATCAA CGTCCAGTAC 
AAGCTGCATT CCTCTGGTGC CAACTGCAGC ACGCTAGGGG TGGTCACCTC AGCCGAGGAC 
ACCTCGGGGA TCCTGTTTGT GAATGACACC AAGGCCCTGC GGCGGCCCAA GTGTGCCGAA 
CTTCACTACA TGGTGGTGGC CACCGACCAG CAGACCTCTA GGCAGGCCCA GGCCCAGCTG 
CTTGTAACAG TGGAGGGGTC ATATGTGGCC GAGGAGGCGG GCTGCCCCCT GTCCTGTGCA 
GTCAGCAAGA GACGGCTGGA GTGTGAGGAG TGTGGCGGCC TGGGCTCCCC AACAGGCAGG 
TGTGAGTGGA GGCAAGGAGA TGGCAAAGGG ATCACCAGGA ACTTCTCCAC CTGCTCTCCC 
AGCACCAAGA CCTGCCCCGA CGGCCACTGC GATGTTGTGG AGACCCAAGA CATCAACATT 
TGCCCTCAGG ACTGCCTCCG GGGCAGCATT GTTGGGGGAC ACGAGCCTGG GGAGCCCCGG 
GGGATTAAAG CTGGCTATGG CACCTGCAAC TGCTTCCCTG AGGAGGAGAA GTGCTTCTGC 
GAGCCCGAAG ACATCCAGGA TCCACTGTGC GACGAGCTGT GCCGCACGGT GATCGCAGCC 
GCTGTCCTCT TCTCCTTCAT CGTCTCGGTG CTGCTGTCTG CCTTCTGCAT CCACTGCTAC 
CACAAGTTTG CCCACAAGCC ACCCATCTCC TCAGCTGAGA TGACCTTCCG GAGGCCCGCC 
CAGGCCTTCC CGGTCAGCTA CTCCTCTTCC GGTGCCCGCC GGCCCTCGCT GGACTCCATG 
GAGAACCAGG TCTCCGTGGA TGCCTTCAAG ATCCTGGAGG ATCCAAAGTG GGAATTCCCT 
CGGAAGAACT TGGTTCTTGG AAAAACTCTA GGAGAAGGCG AATTTGGAAA AGTGGTCAAG 
GCAACGGCCT TCCATCTGAA AGGCAGAGCA GGGTACACCA CGGTGGCCGT GAAGATGCTG 
AAAGAGAACG CCTCCCCGAG TGAGCTGCGA GACCTGCTGT CAGAGTTCAA CGTCCTGAAG 
CAGGTCAACC ACCCACATGT CATCAAATTG TATGGGGCCT GCAGCCAGGA TGGCCCGCTC 
CTCCTCATCG TGGAGTACGC CAAATACGGC TCCCTGCGGG GCTTCCTCCG CGAGAGCCGC 
AAAGTGGGGC CTGGCTACCT GGGCAGTGGA GGCAGCCGCA ACTCCAGCTC CCTGGACCAC 
CCGGATGAGC GGGCCCTCAC CATGGGCGAC CTCATCTCAT TTGCCTGGCA GATCTCACAG 
GGGATGCAGT ATCTGGCCGA GATGAAGCTC GTTCATCGGG ACTTGGCAGC CAGAAACATC 
CTGGTAGCTG AGGGGCGGAA GATGAAGATT TCGGATTTCG GCTTGTCCCG AGATGTTTAT 
GAAGAGGATT CCTACGTGAA GAGGAGCCAG GGTCGGATTC CAGTTAAATG GATGGCAATT 
GAATCCCTTT TTGATCATAT CTACACCACG CAAAGTGATG TATGGTCTTT TGGTGTCCTG 
CTGTGGGAGA TCGTGACCCT AGGGGGAAAC CCCTATCCTG GGATTCCTCC TGAGCGGCTC 
TTCAACCTTC TGAAGACCGG CCACCGGATG GAGAGGCCAG ACAACTGCAG CGAGGAGATG 
TACCGCCTGA TGCTGCAATG CTGGAAGCAG GAGCCGGACA AAAGGCCGGT GTTTGCGGAC 
ATCAGCAAAG ACCTGGAGAA GATGATGGTT AAGAGGAGAG ACTACTTGGA CCTTGCGGCG 
TCCACTCCAT CTGACTCCCT GATTTATGAC GACGGCCTCT CAGAGGAGGA GACACCGCTG 
GTGGACTGTA ATAATGCCCC CCTCCCTCGA GCCCTCCCTT CCACATGGAT TGAAAACAAA 
CTCTATGGTA GAATTTCCCA TGCATTTACT AGATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065681.1
CDS	233..3451
Translation	MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAPEEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLTVYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENRPPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELVAVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFDADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNRNLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFAQIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAELHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPRGIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGRISHAFTRF

Target ORF information:

RefSeq Version	NM_020630.5
Organism	Homo sapiens(human)
Definition	Homo sapiens ret proto-oncogene (RET), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020630.5

ORF Insert Sequence:

ATGGCGAAGG CGACGTCCGG TGCCGCGGGG CTGCGTCTGC TGTTGCTGCT GCTGCTGCCG 
CTGCTAGGCA AAGTGGCATT GGGCCTCTAC TTCTCGAGGG ATGCTTACTG GGAGAAGCTG 
TATGTGGACC AGGCAGCCGG CACGCCCTTG CTGTACGTCC ATGCCCTGCG GGACGCCCCT 
GAGGAGGTGC CCAGCTTCCG CCTGGGCCAG CATCTCTACG GCACGTACCG CACACGGCTG 
CATGAGAACA ACTGGATCTG CATCCAGGAG GACACCGGCC TCCTCTACCT TAACCGGAGC 
CTGGACCATA GCTCCTGGGA GAAGCTCAGT GTCCGCAACC GCGGCTTTCC CCTGCTCACC 
GTCTACCTCA AGGTCTTCCT GTCACCCACA TCCCTTCGTG AGGGCGAGTG CCAGTGGCCA 
GGCTGTGCCC GCGTATACTT CTCCTTCTTC AACACCTCCT TTCCAGCCTG CAGCTCCCTC 
AAGCCCCGGG AGCTCTGCTT CCCAGAGACA AGGCCCTCCT TCCGCATTCG GGAGAACCGA 
CCCCCAGGCA CCTTCCACCA GTTCCGCCTG CTGCCTGTGC AGTTCTTGTG CCCCAACATC 
AGCGTGGCCT ACAGGCTCCT GGAGGGTGAG GGTCTGCCCT TCCGCTGCGC CCCGGACAGC 
CTGGAGGTGA GCACGCGCTG GGCCCTGGAC CGCGAGCAGC GGGAGAAGTA CGAGCTGGTG 
GCCGTGTGCA CCGTGCACGC CGGCGCGCGC GAGGAGGTGG TGATGGTGCC CTTCCCGGTG 
ACCGTGTACG ACGAGGACGA CTCGGCGCCC ACCTTCCCCG CGGGCGTCGA CACCGCCAGC 
GCCGTGGTGG AGTTCAAGCG GAAGGAGGAC ACCGTGGTGG CCACGCTGCG TGTCTTCGAT 
GCAGACGTGG TACCTGCATC AGGGGAGCTG GTGAGGCGGT ACACAAGCAC GCTGCTCCCC 
GGGGACACCT GGGCCCAGCA GACCTTCCGG GTGGAACACT GGCCCAACGA GACCTCGGTC 
CAGGCCAACG GCAGCTTCGT GCGGGCGACC GTACATGACT ATAGGCTGGT TCTCAACCGG 
AACCTCTCCA TCTCGGAGAA CCGCACCATG CAGCTGGCGG TGCTGGTCAA TGACTCAGAC 
TTCCAGGGCC CAGGAGCGGG CGTCCTCTTG CTCCACTTCA ACGTGTCGGT GCTGCCGGTC 
AGCCTGCACC TGCCCAGTAC CTACTCCCTC TCCGTGAGCA GGAGGGCTCG CCGATTTGCC 
CAGATCGGGA AAGTCTGTGT GGAAAACTGC CAGGCATTCA GTGGCATCAA CGTCCAGTAC 
AAGCTGCATT CCTCTGGTGC CAACTGCAGC ACGCTAGGGG TGGTCACCTC AGCCGAGGAC 
ACCTCGGGGA TCCTGTTTGT GAATGACACC AAGGCCCTGC GGCGGCCCAA GTGTGCCGAA 
CTTCACTACA TGGTGGTGGC CACCGACCAG CAGACCTCTA GGCAGGCCCA GGCCCAGCTG 
CTTGTAACAG TGGAGGGGTC ATATGTGGCC GAGGAGGCGG GCTGCCCCCT GTCCTGTGCA 
GTCAGCAAGA GACGGCTGGA GTGTGAGGAG TGTGGCGGCC TGGGCTCCCC AACAGGCAGG 
TGTGAGTGGA GGCAAGGAGA TGGCAAAGGG ATCACCAGGA ACTTCTCCAC CTGCTCTCCC 
AGCACCAAGA CCTGCCCCGA CGGCCACTGC GATGTTGTGG AGACCCAAGA CATCAACATT 
TGCCCTCAGG ACTGCCTCCG GGGCAGCATT GTTGGGGGAC ACGAGCCTGG GGAGCCCCGG 
GGGATTAAAG CTGGCTATGG CACCTGCAAC TGCTTCCCTG AGGAGGAGAA GTGCTTCTGC 
GAGCCCGAAG ACATCCAGGA TCCACTGTGC GACGAGCTGT GCCGCACGGT GATCGCAGCC 
GCTGTCCTCT TCTCCTTCAT CGTCTCGGTG CTGCTGTCTG CCTTCTGCAT CCACTGCTAC 
CACAAGTTTG CCCACAAGCC ACCCATCTCC TCAGCTGAGA TGACCTTCCG GAGGCCCGCC 
CAGGCCTTCC CGGTCAGCTA CTCCTCTTCC GGTGCCCGCC GGCCCTCGCT GGACTCCATG 
GAGAACCAGG TCTCCGTGGA TGCCTTCAAG ATCCTGGAGG ATCCAAAGTG GGAATTCCCT 
CGGAAGAACT TGGTTCTTGG AAAAACTCTA GGAGAAGGCG AATTTGGAAA AGTGGTCAAG 
GCAACGGCCT TCCATCTGAA AGGCAGAGCA GGGTACACCA CGGTGGCCGT GAAGATGCTG 
AAAGAGAACG CCTCCCCGAG TGAGCTGCGA GACCTGCTGT CAGAGTTCAA CGTCCTGAAG 
CAGGTCAACC ACCCACATGT CATCAAATTG TATGGGGCCT GCAGCCAGGA TGGCCCGCTC 
CTCCTCATCG TGGAGTACGC CAAATACGGC TCCCTGCGGG GCTTCCTCCG CGAGAGCCGC 
AAAGTGGGGC CTGGCTACCT GGGCAGTGGA GGCAGCCGCA ACTCCAGCTC CCTGGACCAC 
CCGGATGAGC GGGCCCTCAC CATGGGCGAC CTCATCTCAT TTGCCTGGCA GATCTCACAG 
GGGATGCAGT ATCTGGCCGA GATGAAGCTC GTTCATCGGG ACTTGGCAGC CAGAAACATC 
CTGGTAGCTG AGGGGCGGAA GATGAAGATT TCGGATTTCG GCTTGTCCCG AGATGTTTAT 
GAAGAGGATT CCTACGTGAA GAGGAGCCAG GGTCGGATTC CAGTTAAATG GATGGCAATT 
GAATCCCTTT TTGATCATAT CTACACCACG CAAAGTGATG TATGGTCTTT TGGTGTCCTG 
CTGTGGGAGA TCGTGACCCT AGGGGGAAAC CCCTATCCTG GGATTCCTCC TGAGCGGCTC 
TTCAACCTTC TGAAGACCGG CCACCGGATG GAGAGGCCAG ACAACTGCAG CGAGGAGATG 
TACCGCCTGA TGCTGCAATG CTGGAAGCAG GAGCCGGACA AAAGGCCGGT GTTTGCGGAC 
ATCAGCAAAG ACCTGGAGAA GATGATGGTT AAGAGGAGAG ACTACTTGGA CCTTGCGGCG 
TCCACTCCAT CTGACTCCCT GATTTATGAC GACGGCCTCT CAGAGGAGGA GACACCGCTG 
GTGGACTGTA ATAATGCCCC CCTCCCTCGA GCCCTCCCTT CCACATGGAT TGAAAACAAA 
CTCTATGGTA GAATTTCCCA TGCATTTACT AGATTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Associations between RET tagSNPs and their haplotypes and susceptibility, clinical severity, and thyroid function in patients with differentiated thyroid cancer.
PloS one12(11)e0187968(2017)
He C,Ma J,Jiang Y,Su X,Zhang X,Chen W,Ye Z,Deng T,Deng W,Yang A

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RET cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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