CASKIN1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CASKIN1
Entrez Gene ID	57524
Full Name	CASK interacting protein 1
Synonyms	ANKS5A
General protein information	Preferred Names CASK interacting protein 1 Names caskin-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p13.3
Disorder MIM:	612184

mRNA and Protein(s)

mRNA	Protein	Name
NM_020764.4	NP_065815.1	caskin-1
XM_024450361.1	XP_024306129.1	caskin-1 isoform X1
NM_020764.3	NP_065815.1	caskin-1

Pathways from BioSystems

Homologies

	CASKIN1	XP_001084114.1
Homo sapiens (human)	CASKIN1	NP_065815.1
Rattus norvegicus (Norway rat)	Caskin1	NP_542421.2
Canis lupus familiaris (dog)	CASKIN1	XP_005622148.1
Pan troglodytes (chimpanzee)	CASKIN1	XP_523265.4
Bos taurus (cattle)	CASKIN1	XP_002697906.2
Mus musculus (house mouse)	Caskin1	NP_082213.2

Gene Ontology
Bibliography

Related articles in PubMed

The SH3 domain of Caskin1 binds to lysophosphatidic acid suggesting a direct role for the lipid in intracellular signaling.
Koprivanacz K, T?ke O, Besztercei B, Juh?sz T, Radnai L, Mer? B, Mih?ly J, P?ter M, Balogh G, V?gh L, Buday L, Liliom K
Cellular signalling3266-75(2017 Apr)

Tandem SAM domain structure of human Caskin1: a presynaptic, self-assembling scaffold for CASK.
Stafford RL, Hinde E, Knight MJ, Pennella MA, Ear J, Digman MA, Gratton E, Bowie JU
Structure (London, England : 1993)19(12)1826-36(2011 Dec)

The molecular basis of the Caskin1 and Mint1 interaction with CASK.
Stafford RL, Ear J, Knight MJ, Bowie JU
Journal of molecular biology412(1)3-13(2011 Sep)

Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segr? AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, M?gi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, K?nig IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, M?ller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpel?inen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Par? G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietil?inen KH, Pouta A, Ridderstr?le M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, K?h?nen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtim?ki T, Melander O, Mosley TH Jr, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, T?njes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Gr?nberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, V?lzke H, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden AG, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn JN
Nature467(7317)832-8(2010 Oct)

CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with caskin 1, a novel CASK-binding protein.
Tabuchi K, Biederer T, Butz S, Sudhof TC
The Journal of neuroscience : the official journal of the Society for Neuroscience22(11)4264-73(2002 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the SH3 domain of human Caskin1 is a lipid-binding domain rather than a proline-rich motif interacting domain.
Title: The SH3 domain of Caskin1 binds to lysophosphatidic acid suggesting a direct role for the lipid in intracellular signaling.

SAM domains of Caskin1 form a new type of SAM helical polymer.
Title: Tandem SAM domain structure of human Caskin1: a presynaptic, self-assembling scaffold for CASK.

Study shows that a short linear EEIWVLRK peptide motif from Caskin1 is necessary and sufficient for binding CASK.
Title: The molecular basis of the Caskin1 and Mint1 interaction with CASK.

The following CASKIN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CASKIN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu104180	XM_024450361.1 Latest version!	Homo sapiens CASK interacting protein 1 (CASKIN1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
OHu01988	NM_020764.4 Latest version!	Homo sapiens CASK interacting protein 1 (CASKIN1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00
View Old Accession Versions >>
OHu01988	NM_020764.3	Homo sapiens CASK interacting protein 1 (CASKIN1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$727.30 $1039.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CASKIN1 ( XM_024450361.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306129.1 Homo sapiens CASK interacting protein 1 (CASKIN1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu104180
Clone ID Related Accession (Same CDS sequence)	XM_024450361.1
Accession Version	XM_024450361.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	caskin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAGG AGCAGGAGCT GGTGCAGGCG GTGAAGGCGG AGGACGTAGG GACCGCGCAG 
AGGCTGCTGC AGAGGCCGCG GCCCGGGAAG GCCAAGCTCC TGGGTTCCAC CAAGAAGATC 
AATGTCAACT TCCAGGACCC GGATGGCTTC TCGGCTCTGC ACCATGCGGC CCTGAACGGC 
AACACGGAAT TGATCAGCCT GCTGCTGGAG GCCCAGGCCG CTGTGGACAT CAAGGACAAC 
AAAGGCATGC GGCCGCTGCA CTATGCGGCC TGGCAGGGCC GGAAGGAGCC CATGAAGCTG 
GTGCTGAAGG CGGGCTCGGC CGTGAACATC CCGTCTGATG AGGGCCACAT CCCCCTGCAC 
CTGGCGGCCC AGCATGGTCA CTATGATGTG TCTGAGATGC TGCTACAGCA CCAGTCTAAC 
CCGTGCATGG TGGACAACTC GGGGAAGACG CCCCTGGACC TGGCCTGCGA GTTCGGCCGC 
GTTGGGGTGG TCCAGCTGCT CCTCAGCAGC AATATGTGTG CGGCGCTGCT GGAGCCCCGG 
CCGGGAGACG CCACCGACCC CAACGGCACC AGCCCTTTGC ACCTCGCAGC TAAAAACGGC 
CACATCGACA TCATCAGGCT CCTCCTCCAA GCCGGCATCG ACATTAACCG CCAGACCAAG 
TCCGGCACGG CCCTGCACGA GGCTGCGCTC TGCGGAAAGA CAGAGGTGGT GCGGCTGCTG 
CTGGATAGCG GGATCAATGC CCACGTGAGG AACACCTACA GCCAGACAGC CCTGGACATC 
GTGCACCAGT TCACCACGTC CCAGGCCAGC AGGGAGATCA AGCAGCTGTT GCGAGAGGCC 
TCAGCGGCCC TGCAGGTCCG GGCGACCAAG GATTATTGCA ACAATTACGA CCTGACCAGC 
CTCAACGTGA AGGCAGGGGA CATCATCACA GTCCTCGAGC AGCATCCGGA TGGCCGGTGG 
AAGGGCTGCA TCCATGACAA CCGGACGGGC AATGACCGGG TGGGCTACTT CCCGTCCTCC 
CTGGGCGAGG CCATTGTCAA GCGAGCAGGT TCCCGAGCAG GCACTGAACC AAGCCTGCCC 
CAGGGAAGCA GCTCATCGGG ACCCTCTGCA CCCCCAGAGG AGATCTGGGT GCTGAGGAAG 
CCTTTTGCAG GTGGGGACCG AAGCGGCAGC ATTAGCGGCA TGGCTGGCGG CCGGGGCAGC 
GGGGGTCACG CCCTACACGC GGGCTCTGAA GGCGTCAAGC TCCTGGCAAC GGTGCTTTCC 
CAGAAGTCCG TCTCTGAGTC CGGCCCGGGG GACAGCCCCG CCAAGCCTCC GGAAGGCTCT 
GCAGGTGTGG CCCGGTCCCA GCCTCCAGTG GCCCACGCCG GGCAGGTCTA TGGGGAGCAG 
CCGCCCAAGA AGCTGGAGCC AGCATCGGAG GGCAAGGCTA ACCTGGCCGT GTGGCTGTCC 
ATGATCGGCC TGGCCCAGTA CTACAAGGTG TTGGTGGACA ATGGCTACGA GAACATTGAT 
TTCATCACCG ACATCACCTG GGAGGACCTG CAGGAGATCG GCATCACCAA GCTGGGGCAC 
CAGAAGAAGC TGATGCTCGC TGTGAGGAAG CTGGCAGAGC TGCAGAAGGC TGAATACGCC 
AAGTATGAGG GGGGCCCCCT GCGCCGGAAG GCGCCCCAGT CTCTTGAAGT GATGGCCATC 
GAGTCGCCGC CCCCGCCTGA GCCCACACCG GCCGACTGCC AGTCCCCTAA AATGACCACC 
TTCCAGGACA GCGAGCTCAG TGACGAGCTG CAGGCTGCCA TGACTGGCCC GGCTGAGGTG 
GGGCCCACCA CTGAGAAGCC CTCCAGCCAC CTGCCACCCA CCCCGAGGGC CACCACGCGG 
CAGGACTCCA GCCTGGGTGG TCGGGCACGG CACATGAGCA GCTCGCAGGA GCTGCTGGGA 
GATGGGCCCC CTGGGCCCAG CAGCCCCATG TCTCGAAGCC AGGAGTACCT CCTGGATGAG 
GGCCCCGCCC CCGGCACCCC GCCCAGGGAG GCCCGGCCCG GCCGCCACGG CCACAGCATC 
AAGAGGGCCA GCGTGCCCCC CGTGCCTGGC AAGCCACGGC AGGTCCTCCC ACCAGGCACT 
AGCCACTTCA CGCCCCCCCA GACGCCCACC AAAACCCGAC CAGGCTCTCC CCAGGCCCTT 
GGGGGACCTC ATGGTCCAGC CCCAGCTACG GCCAAGGTGA AGCCCACCCC GCAGCTGCTG 
CCGCCGACAG AGCGCCCCAT GTCACCCCGC TCCCTGCCTC AGTCACCGAC GCACCGCGGC 
TTTGCCTACG TGCTGCCCCA GCCCGTGGAG GGCGAGGTGG GGCCGGCTGC CCCGGGGCCT 
GCGCCCCCAC CCGTGCCGAC GGCTGTGCCC ACACTGTGCC TGCCCCCTGA GGCCGACGCG 
GAGCCGGGGC GGCCCAAGAA GCGGGCCCAC AGCCTGAATC GCTATGCGGC GTCCGACAGC 
GAGCCGGAGC GGGACGAGCT GCTGGTGCCT GCGGCTGCCG GCCCCTATGC CACGGTCCAG 
CGGCGCGTGG GCCGCAGCCA CTCAGTGAGG GCGCCCGCAG GTGCCGACAA GAACGTCAAC 
CGCAGCCAGT CCTTTGCCGT GCGGCCCCGA AAGAAGGGGC CCCCGCCGCC CCCACCCAAG 
CGCTCCAGCT CGGCCCTGGC TAGTGCCAAC CTGGCGGATG AGCCGGTGCC TGACGCCGAG 
CCTGAGGATG GCCTGCTGGG GGTCCGGGCA CAGTGCCGGC GGGCCAGTGA CCTGGCCGGC 
AGCGTGGACA CGGGTAGTGC CGGCAGTGTG AAGAGCATCG CGGCCATGCT GGAGCTGTCC 
TCCATTGGGG GTGGGGGCCG GGCTGCCCGC AGGCCTCCTG AGGGCCACCC CACTCCCCGC 
CCTGCCAGCC CAGAGCCGGG CCGGGTGGCC ACCGTGCTGG CCTCAGTGAA ACACAAAGAG 
GCCATCGGGC CTGGCGGGGA GGTGGTGAAC CGGCGCCGCA CGCTCAGCGG GCCAGTCACC 
GGACTTCTGG CCACTGCCCG CCGGGGGCCT GGGGAGTCGG CAGACCCAGG CCCCTTTGTG 
GAGGATGGCA CTGGCCGGCA GCGGCCTCGG GGTCCCTCCA AGGGCGAGGC GGGTGTCGAA 
GGCCCGCCCT TGGCCAAGGT GGAAGCCAGC GCCACACTCA AGAGGCGCAT CCGGGCCAAG 
CAGAACCAGC AGGAGAACGT CAAGTTCATC CTGACCGAGT CTGACACGGT CAAGCGCAGG 
CCCAAGGCCA AGGAGCGGGA GGCCGGGCCT GAGCCACCAC CGCCACTGTC CGTGTACCAT 
AATGGCACTG GCACCGTGCG CCGCCGACCG GCCTCGGAGC AGGCTGGGCC TCCGGAGCTG 
CCTCCACCGC CCCCGCCTGC CGAACCCCCG CCCACCGACC TGGCGCACCT ACCCCCATTG 
CCCCCGCCCG AGGGCGAAGC CCGGAAGCCG GCCAAGCCGC CTGTCTCTCC CAAGCCCGTC 
CTGACGCAGC CTGTGCCCAA GCTCCAGGGC TCGCCCACAC CCACCTCCAA GAAGGTGCCG 
CTGCCAGGCC CTGGCAGCCC AGAGGTGAAG CGCGCCCACG GCACGCCACC GCCCGTGTCT 
CCCAAGCCGC CGCCGCCGCC CACAGCGCCC AAGCCCGTCA AGGCGGTCGC GGGGCTGCCT 
TCGGGCAGCG CCGGCCCTTC ACCCGCACCC TCGCCCGCGC GACAGCCGCC CGCCGCCCTC 
GCCAAGCCGC CCGGTACGCC GCCCTCGCTG GGCGCCAGCC CCGCCAAGCC CCCGTCCCCC 
GGCGCGCCCG CGCTGCACGT GCCCGCCAAG CCCCCGCGAG CCGCCGCCGC CGCCGCCGCC 
GCCGCCGCCG CGCCCCCCGC CCCGCCCGAA GGCGCCTCGC CAGGGGACAG CGCCCGGCAG 
AAACTGGAGG AGACAAGCGC GTGCCTGGCC GCGGCGCTGC AGGCGGTGGA GGAGAAGATC 
CGGCAGGAGG ACGCGCAGGG CCCGCGCGAC TCGGCGGCGG AAAAGAGCAC TGGCAGCATC 
CTGGACGACA TCGGCAGCAT GTTCGACGAC CTGGCCGACC AGCTGGATGC CATGCTGGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306129.1
CDS	75..4157
Translation	MGKEQELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCGKTEVVRLLLDSGINAHVRNTYSQTALDIVHQFTTSQASREIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAIVKRAGSRAGTEPSLPQGSSSSGPSAPPEEIWVLRKPFAGGDRSGSISGMAGGRGSGGHALHAGSEGVKLLATVLSQKSVSESGPGDSPAKPPEGSAGVARSQPPVAHAGQVYGEQPPKKLEPASEGKANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRKLAELQKAEYAKYEGGPLRRKAPQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPRDSAAEKSTGSILDDIGSMFDDLADQLDAMLE

Target ORF information:

RefSeq Version	XM_024450361.1
Organism	Homo sapiens(human)
Definition	Homo sapiens CASK interacting protein 1 (CASKIN1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024450361.1

ORF Insert Sequence:

ATGGGGAAGG AGCAGGAGCT GGTGCAGGCG GTGAAGGCGG AGGACGTAGG GACCGCGCAG 
AGGCTGCTGC AGAGGCCGCG GCCCGGGAAG GCCAAGCTCC TGGGTTCCAC CAAGAAGATC 
AATGTCAACT TCCAGGACCC GGATGGCTTC TCGGCTCTGC ACCATGCGGC CCTGAACGGC 
AACACGGAAT TGATCAGCCT GCTGCTGGAG GCCCAGGCCG CTGTGGACAT CAAGGACAAC 
AAAGGCATGC GGCCGCTGCA CTATGCGGCC TGGCAGGGCC GGAAGGAGCC CATGAAGCTG 
GTGCTGAAGG CGGGCTCGGC CGTGAACATC CCGTCTGATG AGGGCCACAT CCCCCTGCAC 
CTGGCGGCCC AGCATGGTCA CTATGATGTG TCTGAGATGC TGCTACAGCA CCAGTCTAAC 
CCGTGCATGG TGGACAACTC GGGGAAGACG CCCCTGGACC TGGCCTGCGA GTTCGGCCGC 
GTTGGGGTGG TCCAGCTGCT CCTCAGCAGC AATATGTGTG CGGCGCTGCT GGAGCCCCGG 
CCGGGAGACG CCACCGACCC CAACGGCACC AGCCCTTTGC ACCTCGCAGC TAAAAACGGC 
CACATCGACA TCATCAGGCT CCTCCTCCAA GCCGGCATCG ACATTAACCG CCAGACCAAG 
TCCGGCACGG CCCTGCACGA GGCTGCGCTC TGCGGAAAGA CAGAGGTGGT GCGGCTGCTG 
CTGGATAGCG GGATCAATGC CCACGTGAGG AACACCTACA GCCAGACAGC CCTGGACATC 
GTGCACCAGT TCACCACGTC CCAGGCCAGC AGGGAGATCA AGCAGCTGTT GCGAGAGGCC 
TCAGCGGCCC TGCAGGTCCG GGCGACCAAG GATTATTGCA ACAATTACGA CCTGACCAGC 
CTCAACGTGA AGGCAGGGGA CATCATCACA GTCCTCGAGC AGCATCCGGA TGGCCGGTGG 
AAGGGCTGCA TCCATGACAA CCGGACGGGC AATGACCGGG TGGGCTACTT CCCGTCCTCC 
CTGGGCGAGG CCATTGTCAA GCGAGCAGGT TCCCGAGCAG GCACTGAACC AAGCCTGCCC 
CAGGGAAGCA GCTCATCGGG ACCCTCTGCA CCCCCAGAGG AGATCTGGGT GCTGAGGAAG 
CCTTTTGCAG GTGGGGACCG AAGCGGCAGC ATTAGCGGCA TGGCTGGCGG CCGGGGCAGC 
GGGGGTCACG CCCTACACGC GGGCTCTGAA GGCGTCAAGC TCCTGGCAAC GGTGCTTTCC 
CAGAAGTCCG TCTCTGAGTC CGGCCCGGGG GACAGCCCCG CCAAGCCTCC GGAAGGCTCT 
GCAGGTGTGG CCCGGTCCCA GCCTCCAGTG GCCCACGCCG GGCAGGTCTA TGGGGAGCAG 
CCGCCCAAGA AGCTGGAGCC AGCATCGGAG GGCAAGGCTA ACCTGGCCGT GTGGCTGTCC 
ATGATCGGCC TGGCCCAGTA CTACAAGGTG TTGGTGGACA ATGGCTACGA GAACATTGAT 
TTCATCACCG ACATCACCTG GGAGGACCTG CAGGAGATCG GCATCACCAA GCTGGGGCAC 
CAGAAGAAGC TGATGCTCGC TGTGAGGAAG CTGGCAGAGC TGCAGAAGGC TGAATACGCC 
AAGTATGAGG GGGGCCCCCT GCGCCGGAAG GCGCCCCAGT CTCTTGAAGT GATGGCCATC 
GAGTCGCCGC CCCCGCCTGA GCCCACACCG GCCGACTGCC AGTCCCCTAA AATGACCACC 
TTCCAGGACA GCGAGCTCAG TGACGAGCTG CAGGCTGCCA TGACTGGCCC GGCTGAGGTG 
GGGCCCACCA CTGAGAAGCC CTCCAGCCAC CTGCCACCCA CCCCGAGGGC CACCACGCGG 
CAGGACTCCA GCCTGGGTGG TCGGGCACGG CACATGAGCA GCTCGCAGGA GCTGCTGGGA 
GATGGGCCCC CTGGGCCCAG CAGCCCCATG TCTCGAAGCC AGGAGTACCT CCTGGATGAG 
GGCCCCGCCC CCGGCACCCC GCCCAGGGAG GCCCGGCCCG GCCGCCACGG CCACAGCATC 
AAGAGGGCCA GCGTGCCCCC CGTGCCTGGC AAGCCACGGC AGGTCCTCCC ACCAGGCACT 
AGCCACTTCA CGCCCCCCCA GACGCCCACC AAAACCCGAC CAGGCTCTCC CCAGGCCCTT 
GGGGGACCTC ATGGTCCAGC CCCAGCTACG GCCAAGGTGA AGCCCACCCC GCAGCTGCTG 
CCGCCGACAG AGCGCCCCAT GTCACCCCGC TCCCTGCCTC AGTCACCGAC GCACCGCGGC 
TTTGCCTACG TGCTGCCCCA GCCCGTGGAG GGCGAGGTGG GGCCGGCTGC CCCGGGGCCT 
GCGCCCCCAC CCGTGCCGAC GGCTGTGCCC ACACTGTGCC TGCCCCCTGA GGCCGACGCG 
GAGCCGGGGC GGCCCAAGAA GCGGGCCCAC AGCCTGAATC GCTATGCGGC GTCCGACAGC 
GAGCCGGAGC GGGACGAGCT GCTGGTGCCT GCGGCTGCCG GCCCCTATGC CACGGTCCAG 
CGGCGCGTGG GCCGCAGCCA CTCAGTGAGG GCGCCCGCAG GTGCCGACAA GAACGTCAAC 
CGCAGCCAGT CCTTTGCCGT GCGGCCCCGA AAGAAGGGGC CCCCGCCGCC CCCACCCAAG 
CGCTCCAGCT CGGCCCTGGC TAGTGCCAAC CTGGCGGATG AGCCGGTGCC TGACGCCGAG 
CCTGAGGATG GCCTGCTGGG GGTCCGGGCA CAGTGCCGGC GGGCCAGTGA CCTGGCCGGC 
AGCGTGGACA CGGGTAGTGC CGGCAGTGTG AAGAGCATCG CGGCCATGCT GGAGCTGTCC 
TCCATTGGGG GTGGGGGCCG GGCTGCCCGC AGGCCTCCTG AGGGCCACCC CACTCCCCGC 
CCTGCCAGCC CAGAGCCGGG CCGGGTGGCC ACCGTGCTGG CCTCAGTGAA ACACAAAGAG 
GCCATCGGGC CTGGCGGGGA GGTGGTGAAC CGGCGCCGCA CGCTCAGCGG GCCAGTCACC 
GGACTTCTGG CCACTGCCCG CCGGGGGCCT GGGGAGTCGG CAGACCCAGG CCCCTTTGTG 
GAGGATGGCA CTGGCCGGCA GCGGCCTCGG GGTCCCTCCA AGGGCGAGGC GGGTGTCGAA 
GGCCCGCCCT TGGCCAAGGT GGAAGCCAGC GCCACACTCA AGAGGCGCAT CCGGGCCAAG 
CAGAACCAGC AGGAGAACGT CAAGTTCATC CTGACCGAGT CTGACACGGT CAAGCGCAGG 
CCCAAGGCCA AGGAGCGGGA GGCCGGGCCT GAGCCACCAC CGCCACTGTC CGTGTACCAT 
AATGGCACTG GCACCGTGCG CCGCCGACCG GCCTCGGAGC AGGCTGGGCC TCCGGAGCTG 
CCTCCACCGC CCCCGCCTGC CGAACCCCCG CCCACCGACC TGGCGCACCT ACCCCCATTG 
CCCCCGCCCG AGGGCGAAGC CCGGAAGCCG GCCAAGCCGC CTGTCTCTCC CAAGCCCGTC 
CTGACGCAGC CTGTGCCCAA GCTCCAGGGC TCGCCCACAC CCACCTCCAA GAAGGTGCCG 
CTGCCAGGCC CTGGCAGCCC AGAGGTGAAG CGCGCCCACG GCACGCCACC GCCCGTGTCT 
CCCAAGCCGC CGCCGCCGCC CACAGCGCCC AAGCCCGTCA AGGCGGTCGC GGGGCTGCCT 
TCGGGCAGCG CCGGCCCTTC ACCCGCACCC TCGCCCGCGC GACAGCCGCC CGCCGCCCTC 
GCCAAGCCGC CCGGTACGCC GCCCTCGCTG GGCGCCAGCC CCGCCAAGCC CCCGTCCCCC 
GGCGCGCCCG CGCTGCACGT GCCCGCCAAG CCCCCGCGAG CCGCCGCCGC CGCCGCCGCC 
GCCGCCGCCG CGCCCCCCGC CCCGCCCGAA GGCGCCTCGC CAGGGGACAG CGCCCGGCAG 
AAACTGGAGG AGACAAGCGC GTGCCTGGCC GCGGCGCTGC AGGCGGTGGA GGAGAAGATC 
CGGCAGGAGG ACGCGCAGGG CCCGCGCGAC TCGGCGGCGG AAAAGAGCAC TGGCAGCATC 
CTGGACGACA TCGGCAGCAT GTTCGACGAC CTGGCCGACC AGCTGGATGC CATGCTGGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASKIN1 ( NM_020764.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_065815.1 Homo sapiens CASK interacting protein 1 (CASKIN1), mRNA.

Price & Availability↑

CloneID	OHu01988
Clone ID Related Accession (Same CDS sequence)	NM_020764.4 , NM_020764.3
Accession Version	NM_020764.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	caskin-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC009065.8 and AF451977.1. On May 17, 2019 this sequence version replaced NM_020764.3. ##Evidence-Data-START## Transcript exon combination :: AF451977.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000343516.8/ ENSP00000345436.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGAAGG AGCAGGAGCT GGTGCAGGCG GTGAAGGCGG AGGACGTAGG GACCGCGCAG 
AGGCTGCTGC AGAGGCCGCG GCCCGGGAAG GCCAAGCTCC TGGGTTCCAC CAAGAAGATC 
AATGTCAACT TCCAGGACCC GGATGGCTTC TCGGCTCTGC ACCATGCGGC CCTGAACGGC 
AACACGGAAT TGATCAGCCT GCTGCTGGAG GCCCAGGCCG CTGTGGACAT CAAGGACAAC 
AAAGGCATGC GGCCGCTGCA CTATGCGGCC TGGCAGGGCC GGAAGGAGCC CATGAAGCTG 
GTGCTGAAGG CGGGCTCGGC CGTGAACATC CCGTCTGATG AGGGCCACAT CCCCCTGCAC 
CTGGCGGCCC AGCATGGTCA CTATGATGTG TCTGAGATGC TGCTACAGCA CCAGTCTAAC 
CCGTGCATGG TGGACAACTC GGGGAAGACG CCCCTGGACC TGGCCTGCGA GTTCGGCCGC 
GTTGGGGTGG TCCAGCTGCT CCTCAGCAGC AATATGTGTG CGGCGCTGCT GGAGCCCCGG 
CCGGGAGACG CCACCGACCC CAACGGCACC AGCCCTTTGC ACCTCGCAGC TAAAAACGGC 
CACATCGACA TCATCAGGCT CCTCCTCCAA GCCGGCATCG ACATTAACCG CCAGACCAAG 
TCCGGCACGG CCCTGCACGA GGCTGCGCTC TGCGGAAAGA CAGAGGTGGT GCGGCTGCTG 
CTGGATAGCG GGATCAATGC CCACGTGAGG AACACCTACA GCCAGACAGC CCTGGACATC 
GTGCACCAGT TCACCACGTC CCAGGCCAGC AGGGAGATCA AGCAGCTGTT GCGAGAGGCC 
TCAGCGGCCC TGCAGGTCCG GGCGACCAAG GATTATTGCA ACAATTACGA CCTGACCAGC 
CTCAACGTGA AGGCAGGGGA CATCATCACA GTCCTCGAGC AGCATCCGGA TGGCCGGTGG 
AAGGGCTGCA TCCATGACAA CCGGACGGGC AATGACCGGG TGGGCTACTT CCCGTCCTCC 
CTGGGCGAGG CCATTGTCAA GCGAGCAGGT TCCCGAGCAG GCACTGAACC AAGCCTGCCC 
CAGGGAAGCA GCTCATCGGG ACCCTCTGCA CCCCCAGAGG AGATCTGGGT GCTGAGGAAG 
CCTTTTGCAG GTGGGGACCG AAGCGGCAGC ATTAGCGGCA TGGCTGGCGG CCGGGGCAGC 
GGGGGTCACG CCCTACACGC GGGCTCTGAA GGCGTCAAGC TCCTGGCAAC GGTGCTTTCC 
CAGAAGTCCG TCTCTGAGTC CGGCCCGGGG GACAGCCCCG CCAAGCCTCC GGAAGGCTCT 
GCAGGTGTGG CCCGGTCCCA GCCTCCAGTG GCCCACGCCG GGCAGGTCTA TGGGGAGCAG 
CCGCCCAAGA AGCTGGAGCC AGCATCGGAG GGCAAGAGCT CTGAGGCCGT GAGCCAGTGG 
CTCACCGCGT TCCAGCTGCA GCTCTACGCC CCCAACTTCA TCAGCGCCGG CTACGACCTG 
CCCACCATCA GCCGCATGAC TCCCGAGGAC CTCACGGCCA TTGGTGTCAC CAAGCCGGGC 
CACCGGAAGA AGATCGCGGC AGAGATCAGC GGCCTAAGCA TCCCTGACTG GCTGCCTGAG 
CACAAACCCG CTAACCTGGC CGTGTGGCTG TCCATGATCG GCCTGGCCCA GTACTACAAG 
GTGTTGGTGG ACAATGGCTA CGAGAACATT GATTTCATCA CCGACATCAC CTGGGAGGAC 
CTGCAGGAGA TCGGCATCAC CAAGCTGGGG CACCAGAAGA AGCTGATGCT CGCTGTGAGG 
AAGCTGGCAG AGCTGCAGAA GGCTGAATAC GCCAAGTATG AGGGGGGCCC CCTGCGCCGG 
AAGGCGCCCC AGTCTCTTGA AGTGATGGCC ATCGAGTCGC CGCCCCCGCC TGAGCCCACA 
CCGGCCGACT GCCAGTCCCC TAAAATGACC ACCTTCCAGG ACAGCGAGCT CAGTGACGAG 
CTGCAGGCTG CCATGACTGG CCCGGCTGAG GTGGGGCCCA CCACTGAGAA GCCCTCCAGC 
CACCTGCCAC CCACCCCGAG GGCCACCACG CGGCAGGACT CCAGCCTGGG TGGTCGGGCA 
CGGCACATGA GCAGCTCGCA GGAGCTGCTG GGAGATGGGC CCCCTGGGCC CAGCAGCCCC 
ATGTCTCGAA GCCAGGAGTA CCTCCTGGAT GAGGGCCCCG CCCCCGGCAC CCCGCCCAGG 
GAGGCCCGGC CCGGCCGCCA CGGCCACAGC ATCAAGAGGG CCAGCGTGCC CCCCGTGCCT 
GGCAAGCCAC GGCAGGTCCT CCCACCAGGC ACTAGCCACT TCACGCCCCC CCAGACGCCC 
ACCAAAACCC GACCAGGCTC TCCCCAGGCC CTTGGGGGAC CTCATGGTCC AGCCCCAGCT 
ACGGCCAAGG TGAAGCCCAC CCCGCAGCTG CTGCCGCCGA CAGAGCGCCC CATGTCACCC 
CGCTCCCTGC CTCAGTCACC GACGCACCGC GGCTTTGCCT ACGTGCTGCC CCAGCCCGTG 
GAGGGCGAGG TGGGGCCGGC TGCCCCGGGG CCTGCGCCCC CACCCGTGCC GACGGCTGTG 
CCCACACTGT GCCTGCCCCC TGAGGCCGAC GCGGAGCCGG GGCGGCCCAA GAAGCGGGCC 
CACAGCCTGA ATCGCTATGC GGCGTCCGAC AGCGAGCCGG AGCGGGACGA GCTGCTGGTG 
CCTGCGGCTG CCGGCCCCTA TGCCACGGTC CAGCGGCGCG TGGGCCGCAG CCACTCAGTG 
AGGGCGCCCG CAGGTGCCGA CAAGAACGTC AACCGCAGCC AGTCCTTTGC CGTGCGGCCC 
CGAAAGAAGG GGCCCCCGCC GCCCCCACCC AAGCGCTCCA GCTCGGCCCT GGCTAGTGCC 
AACCTGGCGG ATGAGCCGGT GCCTGACGCC GAGCCTGAGG ATGGCCTGCT GGGGGTCCGG 
GCACAGTGCC GGCGGGCCAG TGACCTGGCC GGCAGCGTGG ACACGGGTAG TGCCGGCAGT 
GTGAAGAGCA TCGCGGCCAT GCTGGAGCTG TCCTCCATTG GGGGTGGGGG CCGGGCTGCC 
CGCAGGCCTC CTGAGGGCCA CCCCACTCCC CGCCCTGCCA GCCCAGAGCC GGGCCGGGTG 
GCCACCGTGC TGGCCTCAGT GAAACACAAA GAGGCCATCG GGCCTGGCGG GGAGGTGGTG 
AACCGGCGCC GCACGCTCAG CGGGCCAGTC ACCGGACTTC TGGCCACTGC CCGCCGGGGG 
CCTGGGGAGT CGGCAGACCC AGGCCCCTTT GTGGAGGATG GCACTGGCCG GCAGCGGCCT 
CGGGGTCCCT CCAAGGGCGA GGCGGGTGTC GAAGGCCCGC CCTTGGCCAA GGTGGAAGCC 
AGCGCCACAC TCAAGAGGCG CATCCGGGCC AAGCAGAACC AGCAGGAGAA CGTCAAGTTC 
ATCCTGACCG AGTCTGACAC GGTCAAGCGC AGGCCCAAGG CCAAGGAGCG GGAGGCCGGG 
CCTGAGCCAC CACCGCCACT GTCCGTGTAC CATAATGGCA CTGGCACCGT GCGCCGCCGA 
CCGGCCTCGG AGCAGGCTGG GCCTCCGGAG CTGCCTCCAC CGCCCCCGCC TGCCGAACCC 
CCGCCCACCG ACCTGGCGCA CCTACCCCCA TTGCCCCCGC CCGAGGGCGA AGCCCGGAAG 
CCGGCCAAGC CGCCTGTCTC TCCCAAGCCC GTCCTGACGC AGCCTGTGCC CAAGCTCCAG 
GGCTCGCCCA CACCCACCTC CAAGAAGGTG CCGCTGCCAG GCCCTGGCAG CCCAGAGGTG 
AAGCGCGCCC ACGGCACGCC ACCGCCCGTG TCTCCCAAGC CGCCGCCGCC GCCCACAGCG 
CCCAAGCCCG TCAAGGCGGT CGCGGGGCTG CCTTCGGGCA GCGCCGGCCC TTCACCCGCA 
CCCTCGCCCG CGCGACAGCC GCCCGCCGCC CTCGCCAAGC CGCCCGGTAC GCCGCCCTCG 
CTGGGCGCCA GCCCCGCCAA GCCCCCGTCC CCCGGCGCGC CCGCGCTGCA CGTGCCCGCC 
AAGCCCCCGC GAGCCGCCGC CGCCGCCGCC GCCGCCGCCG CCGCGCCCCC CGCCCCGCCC 
GAAGGCGCCT CGCCAGGGGA CAGCGCCCGG CAGAAACTGG AGGAGACAAG CGCGTGCCTG 
GCCGCGGCGC TGCAGGCGGT GGAGGAGAAG ATCCGGCAGG AGGACGCGCA GGGCCCGCGC 
GACTCGGCGG CGGAAAAGAG CACTGGCAGC ATCCTGGACG ACATCGGCAG CATGTTCGAC 
GACCTGGCCG ACCAGCTGGA TGCCATGCTG GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065815.1
CDS	174..4469
Translation	MGKEQELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCGKTEVVRLLLDSGINAHVRNTYSQTALDIVHQFTTSQASREIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAIVKRAGSRAGTEPSLPQGSSSSGPSAPPEEIWVLRKPFAGGDRSGSISGMAGGRGSGGHALHAGSEGVKLLATVLSQKSVSESGPGDSPAKPPEGSAGVARSQPPVAHAGQVYGEQPPKKLEPASEGKSSEAVSQWLTAFQLQLYAPNFISAGYDLPTISRMTPEDLTAIGVTKPGHRKKIAAEISGLSIPDWLPEHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRKLAELQKAEYAKYEGGPLRRKAPQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPRDSAAEKSTGSILDDIGSMFDDLADQLDAMLE

Target ORF information:

RefSeq Version	NM_020764.4
Organism	Homo sapiens(human)
Definition	Homo sapiens CASK interacting protein 1 (CASKIN1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020764.4

ORF Insert Sequence:

ATGGGGAAGG AGCAGGAGCT GGTGCAGGCG GTGAAGGCGG AGGACGTAGG GACCGCGCAG 
AGGCTGCTGC AGAGGCCGCG GCCCGGGAAG GCCAAGCTCC TGGGTTCCAC CAAGAAGATC 
AATGTCAACT TCCAGGACCC GGATGGCTTC TCGGCTCTGC ACCATGCGGC CCTGAACGGC 
AACACGGAAT TGATCAGCCT GCTGCTGGAG GCCCAGGCCG CTGTGGACAT CAAGGACAAC 
AAAGGCATGC GGCCGCTGCA CTATGCGGCC TGGCAGGGCC GGAAGGAGCC CATGAAGCTG 
GTGCTGAAGG CGGGCTCGGC CGTGAACATC CCGTCTGATG AGGGCCACAT CCCCCTGCAC 
CTGGCGGCCC AGCATGGTCA CTATGATGTG TCTGAGATGC TGCTACAGCA CCAGTCTAAC 
CCGTGCATGG TGGACAACTC GGGGAAGACG CCCCTGGACC TGGCCTGCGA GTTCGGCCGC 
GTTGGGGTGG TCCAGCTGCT CCTCAGCAGC AATATGTGTG CGGCGCTGCT GGAGCCCCGG 
CCGGGAGACG CCACCGACCC CAACGGCACC AGCCCTTTGC ACCTCGCAGC TAAAAACGGC 
CACATCGACA TCATCAGGCT CCTCCTCCAA GCCGGCATCG ACATTAACCG CCAGACCAAG 
TCCGGCACGG CCCTGCACGA GGCTGCGCTC TGCGGAAAGA CAGAGGTGGT GCGGCTGCTG 
CTGGATAGCG GGATCAATGC CCACGTGAGG AACACCTACA GCCAGACAGC CCTGGACATC 
GTGCACCAGT TCACCACGTC CCAGGCCAGC AGGGAGATCA AGCAGCTGTT GCGAGAGGCC 
TCAGCGGCCC TGCAGGTCCG GGCGACCAAG GATTATTGCA ACAATTACGA CCTGACCAGC 
CTCAACGTGA AGGCAGGGGA CATCATCACA GTCCTCGAGC AGCATCCGGA TGGCCGGTGG 
AAGGGCTGCA TCCATGACAA CCGGACGGGC AATGACCGGG TGGGCTACTT CCCGTCCTCC 
CTGGGCGAGG CCATTGTCAA GCGAGCAGGT TCCCGAGCAG GCACTGAACC AAGCCTGCCC 
CAGGGAAGCA GCTCATCGGG ACCCTCTGCA CCCCCAGAGG AGATCTGGGT GCTGAGGAAG 
CCTTTTGCAG GTGGGGACCG AAGCGGCAGC ATTAGCGGCA TGGCTGGCGG CCGGGGCAGC 
GGGGGTCACG CCCTACACGC GGGCTCTGAA GGCGTCAAGC TCCTGGCAAC GGTGCTTTCC 
CAGAAGTCCG TCTCTGAGTC CGGCCCGGGG GACAGCCCCG CCAAGCCTCC GGAAGGCTCT 
GCAGGTGTGG CCCGGTCCCA GCCTCCAGTG GCCCACGCCG GGCAGGTCTA TGGGGAGCAG 
CCGCCCAAGA AGCTGGAGCC AGCATCGGAG GGCAAGAGCT CTGAGGCCGT GAGCCAGTGG 
CTCACCGCGT TCCAGCTGCA GCTCTACGCC CCCAACTTCA TCAGCGCCGG CTACGACCTG 
CCCACCATCA GCCGCATGAC TCCCGAGGAC CTCACGGCCA TTGGTGTCAC CAAGCCGGGC 
CACCGGAAGA AGATCGCGGC AGAGATCAGC GGCCTAAGCA TCCCTGACTG GCTGCCTGAG 
CACAAACCCG CTAACCTGGC CGTGTGGCTG TCCATGATCG GCCTGGCCCA GTACTACAAG 
GTGTTGGTGG ACAATGGCTA CGAGAACATT GATTTCATCA CCGACATCAC CTGGGAGGAC 
CTGCAGGAGA TCGGCATCAC CAAGCTGGGG CACCAGAAGA AGCTGATGCT CGCTGTGAGG 
AAGCTGGCAG AGCTGCAGAA GGCTGAATAC GCCAAGTATG AGGGGGGCCC CCTGCGCCGG 
AAGGCGCCCC AGTCTCTTGA AGTGATGGCC ATCGAGTCGC CGCCCCCGCC TGAGCCCACA 
CCGGCCGACT GCCAGTCCCC TAAAATGACC ACCTTCCAGG ACAGCGAGCT CAGTGACGAG 
CTGCAGGCTG CCATGACTGG CCCGGCTGAG GTGGGGCCCA CCACTGAGAA GCCCTCCAGC 
CACCTGCCAC CCACCCCGAG GGCCACCACG CGGCAGGACT CCAGCCTGGG TGGTCGGGCA 
CGGCACATGA GCAGCTCGCA GGAGCTGCTG GGAGATGGGC CCCCTGGGCC CAGCAGCCCC 
ATGTCTCGAA GCCAGGAGTA CCTCCTGGAT GAGGGCCCCG CCCCCGGCAC CCCGCCCAGG 
GAGGCCCGGC CCGGCCGCCA CGGCCACAGC ATCAAGAGGG CCAGCGTGCC CCCCGTGCCT 
GGCAAGCCAC GGCAGGTCCT CCCACCAGGC ACTAGCCACT TCACGCCCCC CCAGACGCCC 
ACCAAAACCC GACCAGGCTC TCCCCAGGCC CTTGGGGGAC CTCATGGTCC AGCCCCAGCT 
ACGGCCAAGG TGAAGCCCAC CCCGCAGCTG CTGCCGCCGA CAGAGCGCCC CATGTCACCC 
CGCTCCCTGC CTCAGTCACC GACGCACCGC GGCTTTGCCT ACGTGCTGCC CCAGCCCGTG 
GAGGGCGAGG TGGGGCCGGC TGCCCCGGGG CCTGCGCCCC CACCCGTGCC GACGGCTGTG 
CCCACACTGT GCCTGCCCCC TGAGGCCGAC GCGGAGCCGG GGCGGCCCAA GAAGCGGGCC 
CACAGCCTGA ATCGCTATGC GGCGTCCGAC AGCGAGCCGG AGCGGGACGA GCTGCTGGTG 
CCTGCGGCTG CCGGCCCCTA TGCCACGGTC CAGCGGCGCG TGGGCCGCAG CCACTCAGTG 
AGGGCGCCCG CAGGTGCCGA CAAGAACGTC AACCGCAGCC AGTCCTTTGC CGTGCGGCCC 
CGAAAGAAGG GGCCCCCGCC GCCCCCACCC AAGCGCTCCA GCTCGGCCCT GGCTAGTGCC 
AACCTGGCGG ATGAGCCGGT GCCTGACGCC GAGCCTGAGG ATGGCCTGCT GGGGGTCCGG 
GCACAGTGCC GGCGGGCCAG TGACCTGGCC GGCAGCGTGG ACACGGGTAG TGCCGGCAGT 
GTGAAGAGCA TCGCGGCCAT GCTGGAGCTG TCCTCCATTG GGGGTGGGGG CCGGGCTGCC 
CGCAGGCCTC CTGAGGGCCA CCCCACTCCC CGCCCTGCCA GCCCAGAGCC GGGCCGGGTG 
GCCACCGTGC TGGCCTCAGT GAAACACAAA GAGGCCATCG GGCCTGGCGG GGAGGTGGTG 
AACCGGCGCC GCACGCTCAG CGGGCCAGTC ACCGGACTTC TGGCCACTGC CCGCCGGGGG 
CCTGGGGAGT CGGCAGACCC AGGCCCCTTT GTGGAGGATG GCACTGGCCG GCAGCGGCCT 
CGGGGTCCCT CCAAGGGCGA GGCGGGTGTC GAAGGCCCGC CCTTGGCCAA GGTGGAAGCC 
AGCGCCACAC TCAAGAGGCG CATCCGGGCC AAGCAGAACC AGCAGGAGAA CGTCAAGTTC 
ATCCTGACCG AGTCTGACAC GGTCAAGCGC AGGCCCAAGG CCAAGGAGCG GGAGGCCGGG 
CCTGAGCCAC CACCGCCACT GTCCGTGTAC CATAATGGCA CTGGCACCGT GCGCCGCCGA 
CCGGCCTCGG AGCAGGCTGG GCCTCCGGAG CTGCCTCCAC CGCCCCCGCC TGCCGAACCC 
CCGCCCACCG ACCTGGCGCA CCTACCCCCA TTGCCCCCGC CCGAGGGCGA AGCCCGGAAG 
CCGGCCAAGC CGCCTGTCTC TCCCAAGCCC GTCCTGACGC AGCCTGTGCC CAAGCTCCAG 
GGCTCGCCCA CACCCACCTC CAAGAAGGTG CCGCTGCCAG GCCCTGGCAG CCCAGAGGTG 
AAGCGCGCCC ACGGCACGCC ACCGCCCGTG TCTCCCAAGC CGCCGCCGCC GCCCACAGCG 
CCCAAGCCCG TCAAGGCGGT CGCGGGGCTG CCTTCGGGCA GCGCCGGCCC TTCACCCGCA 
CCCTCGCCCG CGCGACAGCC GCCCGCCGCC CTCGCCAAGC CGCCCGGTAC GCCGCCCTCG 
CTGGGCGCCA GCCCCGCCAA GCCCCCGTCC CCCGGCGCGC CCGCGCTGCA CGTGCCCGCC 
AAGCCCCCGC GAGCCGCCGC CGCCGCCGCC GCCGCCGCCG CCGCGCCCCC CGCCCCGCCC 
GAAGGCGCCT CGCCAGGGGA CAGCGCCCGG CAGAAACTGG AGGAGACAAG CGCGTGCCTG 
GCCGCGGCGC TGCAGGCGGT GGAGGAGAAG ATCCGGCAGG AGGACGCGCA GGGCCCGCGC 
GACTCGGCGG CGGAAAAGAG CACTGGCAGC ATCCTGGACG ACATCGGCAG CATGTTCGAC 
GACCTGGCCG ACCAGCTGGA TGCCATGCTG GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CASKIN1 ( NM_020764.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_065815.1 Homo sapiens CASK interacting protein 1 (CASKIN1), mRNA.

Price & Availability↑

CloneID	OHu01988
Clone ID Related Accession (Same CDS sequence)	NM_020764.4 , NM_020764.3
Accession Version	NM_020764.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Homo sapiens(human)
Product	caskin-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF451977.1 and AC009065.8. On May 7, 2009 this sequence version replaced NM_020764.2. ##Evidence-Data-START## Transcript exon combination :: AF451977.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAAGG AGCAGGAGCT GGTGCAGGCG GTGAAGGCGG AGGACGTAGG GACCGCGCAG 
AGGCTGCTGC AGAGGCCGCG GCCCGGGAAG GCCAAGCTCC TGGGTTCCAC CAAGAAGATC 
AATGTCAACT TCCAGGACCC GGATGGCTTC TCGGCTCTGC ACCATGCGGC CCTGAACGGC 
AACACGGAAT TGATCAGCCT GCTGCTGGAG GCCCAGGCCG CTGTGGACAT CAAGGACAAC 
AAAGGCATGC GGCCGCTGCA CTATGCGGCC TGGCAGGGCC GGAAGGAGCC CATGAAGCTG 
GTGCTGAAGG CGGGCTCGGC CGTGAACATC CCGTCTGATG AGGGCCACAT CCCCCTGCAC 
CTGGCGGCCC AGCATGGTCA CTATGATGTG TCTGAGATGC TGCTACAGCA CCAGTCTAAC 
CCGTGCATGG TGGACAACTC GGGGAAGACG CCCCTGGACC TGGCCTGCGA GTTCGGCCGC 
GTTGGGGTGG TCCAGCTGCT CCTCAGCAGC AATATGTGTG CGGCGCTGCT GGAGCCCCGG 
CCGGGAGACG CCACCGACCC CAACGGCACC AGCCCTTTGC ACCTCGCAGC TAAAAACGGC 
CACATCGACA TCATCAGGCT CCTCCTCCAA GCCGGCATCG ACATTAACCG CCAGACCAAG 
TCCGGCACGG CCCTGCACGA GGCTGCGCTC TGCGGAAAGA CAGAGGTGGT GCGGCTGCTG 
CTGGATAGCG GGATCAATGC CCACGTGAGG AACACCTACA GCCAGACAGC CCTGGACATC 
GTGCACCAGT TCACCACGTC CCAGGCCAGC AGGGAGATCA AGCAGCTGTT GCGAGAGGCC 
TCAGCGGCCC TGCAGGTCCG GGCGACCAAG GATTATTGCA ACAATTACGA CCTGACCAGC 
CTCAACGTGA AGGCAGGGGA CATCATCACA GTCCTCGAGC AGCATCCGGA TGGCCGGTGG 
AAGGGCTGCA TCCATGACAA CCGGACGGGC AATGACCGGG TGGGCTACTT CCCGTCCTCC 
CTGGGCGAGG CCATTGTCAA GCGAGCAGGT TCCCGAGCAG GCACTGAACC AAGCCTGCCC 
CAGGGAAGCA GCTCATCGGG ACCCTCTGCA CCCCCAGAGG AGATCTGGGT GCTGAGGAAG 
CCTTTTGCAG GTGGGGACCG AAGCGGCAGC ATTAGCGGCA TGGCTGGCGG CCGGGGCAGC 
GGGGGTCACG CCCTACACGC GGGCTCTGAA GGCGTCAAGC TCCTGGCAAC GGTGCTTTCC 
CAGAAGTCCG TCTCTGAGTC CGGCCCGGGG GACAGCCCCG CCAAGCCTCC GGAAGGCTCT 
GCAGGTGTGG CCCGGTCCCA GCCTCCAGTG GCCCACGCCG GGCAGGTCTA TGGGGAGCAG 
CCGCCCAAGA AGCTGGAGCC AGCATCGGAG GGCAAGAGCT CTGAGGCCGT GAGCCAGTGG 
CTCACCGCGT TCCAGCTGCA GCTCTACGCC CCCAACTTCA TCAGCGCCGG CTACGACCTG 
CCCACCATCA GCCGCATGAC TCCCGAGGAC CTCACGGCCA TTGGTGTCAC CAAGCCGGGC 
CACCGGAAGA AGATCGCGGC AGAGATCAGC GGCCTAAGCA TCCCTGACTG GCTGCCTGAG 
CACAAACCCG CTAACCTGGC CGTGTGGCTG TCCATGATCG GCCTGGCCCA GTACTACAAG 
GTGTTGGTGG ACAATGGCTA CGAGAACATT GATTTCATCA CCGACATCAC CTGGGAGGAC 
CTGCAGGAGA TCGGCATCAC CAAGCTGGGG CACCAGAAGA AGCTGATGCT CGCTGTGAGG 
AAGCTGGCAG AGCTGCAGAA GGCTGAATAC GCCAAGTATG AGGGGGGCCC CCTGCGCCGG 
AAGGCGCCCC AGTCTCTTGA AGTGATGGCC ATCGAGTCGC CGCCCCCGCC TGAGCCCACA 
CCGGCCGACT GCCAGTCCCC TAAAATGACC ACCTTCCAGG ACAGCGAGCT CAGTGACGAG 
CTGCAGGCTG CCATGACTGG CCCGGCTGAG GTGGGGCCCA CCACTGAGAA GCCCTCCAGC 
CACCTGCCAC CCACCCCGAG GGCCACCACG CGGCAGGACT CCAGCCTGGG TGGTCGGGCA 
CGGCACATGA GCAGCTCGCA GGAGCTGCTG GGAGATGGGC CCCCTGGGCC CAGCAGCCCC 
ATGTCTCGAA GCCAGGAGTA CCTCCTGGAT GAGGGCCCCG CCCCCGGCAC CCCGCCCAGG 
GAGGCCCGGC CCGGCCGCCA CGGCCACAGC ATCAAGAGGG CCAGCGTGCC CCCCGTGCCT 
GGCAAGCCAC GGCAGGTCCT CCCACCAGGC ACTAGCCACT TCACGCCCCC CCAGACGCCC 
ACCAAAACCC GACCAGGCTC TCCCCAGGCC CTTGGGGGAC CTCATGGTCC AGCCCCAGCT 
ACGGCCAAGG TGAAGCCCAC CCCGCAGCTG CTGCCGCCGA CAGAGCGCCC CATGTCACCC 
CGCTCCCTGC CTCAGTCACC GACGCACCGC GGCTTTGCCT ACGTGCTGCC CCAGCCCGTG 
GAGGGCGAGG TGGGGCCGGC TGCCCCGGGG CCTGCGCCCC CACCCGTGCC GACGGCTGTG 
CCCACACTGT GCCTGCCCCC TGAGGCCGAC GCGGAGCCGG GGCGGCCCAA GAAGCGGGCC 
CACAGCCTGA ATCGCTATGC GGCGTCCGAC AGCGAGCCGG AGCGGGACGA GCTGCTGGTG 
CCTGCGGCTG CCGGCCCCTA TGCCACGGTC CAGCGGCGCG TGGGCCGCAG CCACTCAGTG 
AGGGCGCCCG CAGGTGCCGA CAAGAACGTC AACCGCAGCC AGTCCTTTGC CGTGCGGCCC 
CGAAAGAAGG GGCCCCCGCC GCCCCCACCC AAGCGCTCCA GCTCGGCCCT GGCTAGTGCC 
AACCTGGCGG ATGAGCCGGT GCCTGACGCC GAGCCTGAGG ATGGCCTGCT GGGGGTCCGG 
GCACAGTGCC GGCGGGCCAG TGACCTGGCC GGCAGCGTGG ACACGGGTAG TGCCGGCAGT 
GTGAAGAGCA TCGCGGCCAT GCTGGAGCTG TCCTCCATTG GGGGTGGGGG CCGGGCTGCC 
CGCAGGCCTC CTGAGGGCCA CCCCACTCCC CGCCCTGCCA GCCCAGAGCC GGGCCGGGTG 
GCCACCGTGC TGGCCTCAGT GAAACACAAA GAGGCCATCG GGCCTGGCGG GGAGGTGGTG 
AACCGGCGCC GCACGCTCAG CGGGCCAGTC ACCGGACTTC TGGCCACTGC CCGCCGGGGG 
CCTGGGGAGT CGGCAGACCC AGGCCCCTTT GTGGAGGATG GCACTGGCCG GCAGCGGCCT 
CGGGGTCCCT CCAAGGGCGA GGCGGGTGTC GAAGGCCCGC CCTTGGCCAA GGTGGAAGCC 
AGCGCCACAC TCAAGAGGCG CATCCGGGCC AAGCAGAACC AGCAGGAGAA CGTCAAGTTC 
ATCCTGACCG AGTCTGACAC GGTCAAGCGC AGGCCCAAGG CCAAGGAGCG GGAGGCCGGG 
CCTGAGCCAC CACCGCCACT GTCCGTGTAC CATAATGGCA CTGGCACCGT GCGCCGCCGA 
CCGGCCTCGG AGCAGGCTGG GCCTCCGGAG CTGCCTCCAC CGCCCCCGCC TGCCGAACCC 
CCGCCCACCG ACCTGGCGCA CCTACCCCCA TTGCCCCCGC CCGAGGGCGA AGCCCGGAAG 
CCGGCCAAGC CGCCTGTCTC TCCCAAGCCC GTCCTGACGC AGCCTGTGCC CAAGCTCCAG 
GGCTCGCCCA CACCCACCTC CAAGAAGGTG CCGCTGCCAG GCCCTGGCAG CCCAGAGGTG 
AAGCGCGCCC ACGGCACGCC ACCGCCCGTG TCTCCCAAGC CGCCGCCGCC GCCCACAGCG 
CCCAAGCCCG TCAAGGCGGT CGCGGGGCTG CCTTCGGGCA GCGCCGGCCC TTCACCCGCA 
CCCTCGCCCG CGCGACAGCC GCCCGCCGCC CTCGCCAAGC CGCCCGGTAC GCCGCCCTCG 
CTGGGCGCCA GCCCCGCCAA GCCCCCGTCC CCCGGCGCGC CCGCGCTGCA CGTGCCCGCC 
AAGCCCCCGC GAGCCGCCGC CGCCGCCGCC GCCGCCGCCG CCGCGCCCCC CGCCCCGCCC 
GAAGGCGCCT CGCCAGGGGA CAGCGCCCGG CAGAAACTGG AGGAGACAAG CGCGTGCCTG 
GCCGCGGCGC TGCAGGCGGT GGAGGAGAAG ATCCGGCAGG AGGACGCGCA GGGCCCGCGC 
GACTCGGCGG CGGAAAAGAG CACTGGCAGC ATCCTGGACG ACATCGGCAG CATGTTCGAC 
GACCTGGCCG ACCAGCTGGA TGCCATGCTG GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065815.1
CDS	33..4328
Translation	MGKEQELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCGKTEVVRLLLDSGINAHVRNTYSQTALDIVHQFTTSQASREIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAIVKRAGSRAGTEPSLPQGSSSSGPSAPPEEIWVLRKPFAGGDRSGSISGMAGGRGSGGHALHAGSEGVKLLATVLSQKSVSESGPGDSPAKPPEGSAGVARSQPPVAHAGQVYGEQPPKKLEPASEGKSSEAVSQWLTAFQLQLYAPNFISAGYDLPTISRMTPEDLTAIGVTKPGHRKKIAAEISGLSIPDWLPEHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRKLAELQKAEYAKYEGGPLRRKAPQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPRDSAAEKSTGSILDDIGSMFDDLADQLDAMLE

Target ORF information:

RefSeq Version	NM_020764.3
Organism	Homo sapiens(human)
Definition	Homo sapiens CASK interacting protein 1 (CASKIN1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020764.3

ORF Insert Sequence:

ATGGGGAAGG AGCAGGAGCT GGTGCAGGCG GTGAAGGCGG AGGACGTAGG GACCGCGCAG 
AGGCTGCTGC AGAGGCCGCG GCCCGGGAAG GCCAAGCTCC TGGGTTCCAC CAAGAAGATC 
AATGTCAACT TCCAGGACCC GGATGGCTTC TCGGCTCTGC ACCATGCGGC CCTGAACGGC 
AACACGGAAT TGATCAGCCT GCTGCTGGAG GCCCAGGCCG CTGTGGACAT CAAGGACAAC 
AAAGGCATGC GGCCGCTGCA CTATGCGGCC TGGCAGGGCC GGAAGGAGCC CATGAAGCTG 
GTGCTGAAGG CGGGCTCGGC CGTGAACATC CCGTCTGATG AGGGCCACAT CCCCCTGCAC 
CTGGCGGCCC AGCATGGTCA CTATGATGTG TCTGAGATGC TGCTACAGCA CCAGTCTAAC 
CCGTGCATGG TGGACAACTC GGGGAAGACG CCCCTGGACC TGGCCTGCGA GTTCGGCCGC 
GTTGGGGTGG TCCAGCTGCT CCTCAGCAGC AATATGTGTG CGGCGCTGCT GGAGCCCCGG 
CCGGGAGACG CCACCGACCC CAACGGCACC AGCCCTTTGC ACCTCGCAGC TAAAAACGGC 
CACATCGACA TCATCAGGCT CCTCCTCCAA GCCGGCATCG ACATTAACCG CCAGACCAAG 
TCCGGCACGG CCCTGCACGA GGCTGCGCTC TGCGGAAAGA CAGAGGTGGT GCGGCTGCTG 
CTGGATAGCG GGATCAATGC CCACGTGAGG AACACCTACA GCCAGACAGC CCTGGACATC 
GTGCACCAGT TCACCACGTC CCAGGCCAGC AGGGAGATCA AGCAGCTGTT GCGAGAGGCC 
TCAGCGGCCC TGCAGGTCCG GGCGACCAAG GATTATTGCA ACAATTACGA CCTGACCAGC 
CTCAACGTGA AGGCAGGGGA CATCATCACA GTCCTCGAGC AGCATCCGGA TGGCCGGTGG 
AAGGGCTGCA TCCATGACAA CCGGACGGGC AATGACCGGG TGGGCTACTT CCCGTCCTCC 
CTGGGCGAGG CCATTGTCAA GCGAGCAGGT TCCCGAGCAG GCACTGAACC AAGCCTGCCC 
CAGGGAAGCA GCTCATCGGG ACCCTCTGCA CCCCCAGAGG AGATCTGGGT GCTGAGGAAG 
CCTTTTGCAG GTGGGGACCG AAGCGGCAGC ATTAGCGGCA TGGCTGGCGG CCGGGGCAGC 
GGGGGTCACG CCCTACACGC GGGCTCTGAA GGCGTCAAGC TCCTGGCAAC GGTGCTTTCC 
CAGAAGTCCG TCTCTGAGTC CGGCCCGGGG GACAGCCCCG CCAAGCCTCC GGAAGGCTCT 
GCAGGTGTGG CCCGGTCCCA GCCTCCAGTG GCCCACGCCG GGCAGGTCTA TGGGGAGCAG 
CCGCCCAAGA AGCTGGAGCC AGCATCGGAG GGCAAGAGCT CTGAGGCCGT GAGCCAGTGG 
CTCACCGCGT TCCAGCTGCA GCTCTACGCC CCCAACTTCA TCAGCGCCGG CTACGACCTG 
CCCACCATCA GCCGCATGAC TCCCGAGGAC CTCACGGCCA TTGGTGTCAC CAAGCCGGGC 
CACCGGAAGA AGATCGCGGC AGAGATCAGC GGCCTAAGCA TCCCTGACTG GCTGCCTGAG 
CACAAACCCG CTAACCTGGC CGTGTGGCTG TCCATGATCG GCCTGGCCCA GTACTACAAG 
GTGTTGGTGG ACAATGGCTA CGAGAACATT GATTTCATCA CCGACATCAC CTGGGAGGAC 
CTGCAGGAGA TCGGCATCAC CAAGCTGGGG CACCAGAAGA AGCTGATGCT CGCTGTGAGG 
AAGCTGGCAG AGCTGCAGAA GGCTGAATAC GCCAAGTATG AGGGGGGCCC CCTGCGCCGG 
AAGGCGCCCC AGTCTCTTGA AGTGATGGCC ATCGAGTCGC CGCCCCCGCC TGAGCCCACA 
CCGGCCGACT GCCAGTCCCC TAAAATGACC ACCTTCCAGG ACAGCGAGCT CAGTGACGAG 
CTGCAGGCTG CCATGACTGG CCCGGCTGAG GTGGGGCCCA CCACTGAGAA GCCCTCCAGC 
CACCTGCCAC CCACCCCGAG GGCCACCACG CGGCAGGACT CCAGCCTGGG TGGTCGGGCA 
CGGCACATGA GCAGCTCGCA GGAGCTGCTG GGAGATGGGC CCCCTGGGCC CAGCAGCCCC 
ATGTCTCGAA GCCAGGAGTA CCTCCTGGAT GAGGGCCCCG CCCCCGGCAC CCCGCCCAGG 
GAGGCCCGGC CCGGCCGCCA CGGCCACAGC ATCAAGAGGG CCAGCGTGCC CCCCGTGCCT 
GGCAAGCCAC GGCAGGTCCT CCCACCAGGC ACTAGCCACT TCACGCCCCC CCAGACGCCC 
ACCAAAACCC GACCAGGCTC TCCCCAGGCC CTTGGGGGAC CTCATGGTCC AGCCCCAGCT 
ACGGCCAAGG TGAAGCCCAC CCCGCAGCTG CTGCCGCCGA CAGAGCGCCC CATGTCACCC 
CGCTCCCTGC CTCAGTCACC GACGCACCGC GGCTTTGCCT ACGTGCTGCC CCAGCCCGTG 
GAGGGCGAGG TGGGGCCGGC TGCCCCGGGG CCTGCGCCCC CACCCGTGCC GACGGCTGTG 
CCCACACTGT GCCTGCCCCC TGAGGCCGAC GCGGAGCCGG GGCGGCCCAA GAAGCGGGCC 
CACAGCCTGA ATCGCTATGC GGCGTCCGAC AGCGAGCCGG AGCGGGACGA GCTGCTGGTG 
CCTGCGGCTG CCGGCCCCTA TGCCACGGTC CAGCGGCGCG TGGGCCGCAG CCACTCAGTG 
AGGGCGCCCG CAGGTGCCGA CAAGAACGTC AACCGCAGCC AGTCCTTTGC CGTGCGGCCC 
CGAAAGAAGG GGCCCCCGCC GCCCCCACCC AAGCGCTCCA GCTCGGCCCT GGCTAGTGCC 
AACCTGGCGG ATGAGCCGGT GCCTGACGCC GAGCCTGAGG ATGGCCTGCT GGGGGTCCGG 
GCACAGTGCC GGCGGGCCAG TGACCTGGCC GGCAGCGTGG ACACGGGTAG TGCCGGCAGT 
GTGAAGAGCA TCGCGGCCAT GCTGGAGCTG TCCTCCATTG GGGGTGGGGG CCGGGCTGCC 
CGCAGGCCTC CTGAGGGCCA CCCCACTCCC CGCCCTGCCA GCCCAGAGCC GGGCCGGGTG 
GCCACCGTGC TGGCCTCAGT GAAACACAAA GAGGCCATCG GGCCTGGCGG GGAGGTGGTG 
AACCGGCGCC GCACGCTCAG CGGGCCAGTC ACCGGACTTC TGGCCACTGC CCGCCGGGGG 
CCTGGGGAGT CGGCAGACCC AGGCCCCTTT GTGGAGGATG GCACTGGCCG GCAGCGGCCT 
CGGGGTCCCT CCAAGGGCGA GGCGGGTGTC GAAGGCCCGC CCTTGGCCAA GGTGGAAGCC 
AGCGCCACAC TCAAGAGGCG CATCCGGGCC AAGCAGAACC AGCAGGAGAA CGTCAAGTTC 
ATCCTGACCG AGTCTGACAC GGTCAAGCGC AGGCCCAAGG CCAAGGAGCG GGAGGCCGGG 
CCTGAGCCAC CACCGCCACT GTCCGTGTAC CATAATGGCA CTGGCACCGT GCGCCGCCGA 
CCGGCCTCGG AGCAGGCTGG GCCTCCGGAG CTGCCTCCAC CGCCCCCGCC TGCCGAACCC 
CCGCCCACCG ACCTGGCGCA CCTACCCCCA TTGCCCCCGC CCGAGGGCGA AGCCCGGAAG 
CCGGCCAAGC CGCCTGTCTC TCCCAAGCCC GTCCTGACGC AGCCTGTGCC CAAGCTCCAG 
GGCTCGCCCA CACCCACCTC CAAGAAGGTG CCGCTGCCAG GCCCTGGCAG CCCAGAGGTG 
AAGCGCGCCC ACGGCACGCC ACCGCCCGTG TCTCCCAAGC CGCCGCCGCC GCCCACAGCG 
CCCAAGCCCG TCAAGGCGGT CGCGGGGCTG CCTTCGGGCA GCGCCGGCCC TTCACCCGCA 
CCCTCGCCCG CGCGACAGCC GCCCGCCGCC CTCGCCAAGC CGCCCGGTAC GCCGCCCTCG 
CTGGGCGCCA GCCCCGCCAA GCCCCCGTCC CCCGGCGCGC CCGCGCTGCA CGTGCCCGCC 
AAGCCCCCGC GAGCCGCCGC CGCCGCCGCC GCCGCCGCCG CCGCGCCCCC CGCCCCGCCC 
GAAGGCGCCT CGCCAGGGGA CAGCGCCCGG CAGAAACTGG AGGAGACAAG CGCGTGCCTG 
GCCGCGGCGC TGCAGGCGGT GGAGGAGAAG ATCCGGCAGG AGGACGCGCA GGGCCCGCGC 
GACTCGGCGG CGGAAAAGAG CACTGGCAGC ATCCTGGACG ACATCGGCAG CATGTTCGAC 
GACCTGGCCG ACCAGCTGGA TGCCATGCTG GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The SH3 domain of Caskin1 binds to lysophosphatidic acid suggesting a direct role for the lipid in intracellular signaling.
Cellular signalling3266-75(2017 Apr)
Koprivanacz K,T?ke O,Besztercei B,Juh?sz T,Radnai L,Mer? B,Mih?ly J,P?ter M,Balogh G,V?gh L,Buday L,Liliom K

Tandem SAM domain structure of human Caskin1: a presynaptic, self-assembling scaffold for CASK.
Structure (London, England : 1993)19(12)1826-36(2011 Dec)
Stafford RL,Hinde E,Knight MJ,Pennella MA,Ear J,Digman MA,Gratton E,Bowie JU

The molecular basis of the Caskin1 and Mint1 interaction with CASK.
Journal of molecular biology412(1)3-13(2011 Sep)
Stafford RL,Ear J,Knight MJ,Bowie JU

Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Nature467(7317)832-8(2010 Oct)
Lango Allen H,Estrada K,Lettre G,Berndt SI,Weedon MN,Rivadeneira F,Willer CJ,Jackson AU,Vedantam S,Raychaudhuri S,Ferreira T,Wood AR,Weyant RJ,Segr? AV,Speliotes EK,Wheeler E,Soranzo N,Park JH,Yang J,Gudbjartsson D,Heard-Costa NL,Randall JC,Qi L,Vernon Smith A,M?gi R,Pastinen T,Liang L,Heid IM,Luan J,Thorleifsson G,Winkler TW,Goddard ME,Sin Lo K,Palmer C,Workalemahu T,Aulchenko YS,Johansson A,Zillikens MC,Feitosa MF,Esko T,Johnson T,Ketkar S,Kraft P,Mangino M,Prokopenko I,Absher D,Albrecht E,Ernst F,Glazer NL,Hayward C,Hottenga JJ,Jacobs KB,Knowles JW,Kutalik Z,Monda KL,Polasek O,Preuss M,Rayner NW,Robertson NR,Steinthorsdottir V,Tyrer JP,Voight BF,Wiklund F,Xu J,Zhao JH,Nyholt DR,Pellikka N,Perola M,Perry JR,Surakka I,Tammesoo ML,Altmaier EL,Amin N,Aspelund T,Bhangale T,Boucher G,Chasman DI,Chen C,Coin L,Cooper MN,Dixon AL,Gibson Q,Grundberg E,Hao K,Juhani Junttila M,Kaplan LM,Kettunen J,K?nig IR,Kwan T,Lawrence RW,Levinson DF,Lorentzon M,McKnight B,Morris AP,M?ller M,Suh Ngwa J,Purcell S,Rafelt S,Salem RM,Salvi E,Sanna S,Shi J,Sovio U,Thompson JR,Turchin MC,Vandenput L,Verlaan DJ,Vitart V,White CC,Ziegler A,Almgren P,Balmforth AJ,Campbell H,Citterio L,De Grandi A,Dominiczak A,Duan J,Elliott P,Elosua R,Eriksson JG,Freimer NB,Geus EJ,Glorioso N,Haiqing S,Hartikainen AL,Havulinna AS,Hicks AA,Hui J,Igl W,Illig T,Jula A,Kajantie E,Kilpel?inen TO,Koiranen M,Kolcic I,Koskinen S,Kovacs P,Laitinen J,Liu J,Lokki ML,Marusic A,Maschio A,Meitinger T,Mulas A,Par? G,Parker AN,Peden JF,Petersmann A,Pichler I,Pietil?inen KH,Pouta A,Ridderstr?le M,Rotter JI,Sambrook JG,Sanders AR,Schmidt CO,Sinisalo J,Smit JH,Stringham HM,Bragi Walters G,Widen E,Wild SH,Willemsen G,Zagato L,Zgaga L,Zitting P,Alavere H,Farrall M,McArdle WL,Nelis M,Peters MJ,Ripatti S,van Meurs JB,Aben KK,Ardlie KG,Beckmann JS,Beilby JP,Bergman RN,Bergmann S,Collins FS,Cusi D,den Heijer M,Eiriksdottir G,Gejman PV,Hall AS,Hamsten A,Huikuri HV,Iribarren C,K?h?nen M,Kaprio J,Kathiresan S,Kiemeney L,Kocher T,Launer LJ,Lehtim?ki T,Melander O,Mosley TH Jr,Musk AW,Nieminen MS,O'Donnell CJ,Ohlsson C,Oostra B,Palmer LJ,Raitakari O,Ridker PM,Rioux JD,Rissanen A,Rivolta C,Schunkert H,Shuldiner AR,Siscovick DS,Stumvoll M,T?njes A,Tuomilehto J,van Ommen GJ,Viikari J,Heath AC,Martin NG,Montgomery GW,Province MA,Kayser M,Arnold AM,Atwood LD,Boerwinkle E,Chanock SJ,Deloukas P,Gieger C,Gr?nberg H,Hall P,Hattersley AT,Hengstenberg C,Hoffman W,Lathrop GM,Salomaa V,Schreiber S,Uda M,Waterworth D,Wright AF,Assimes TL,Barroso I,Hofman A,Mohlke KL,Boomsma DI,Caulfield MJ,Cupples LA,Erdmann J,Fox CS,Gudnason V,Gyllensten U,Harris TB,Hayes RB,Jarvelin MR,Mooser V,Munroe PB,Ouwehand WH,Penninx BW,Pramstaller PP,Quertermous T,Rudan I,Samani NJ,Spector TD,V?lzke H,Watkins H,Wilson JF,Groop LC,Haritunians T,Hu FB,Kaplan RC,Metspalu A,North KE,Schlessinger D,Wareham NJ,Hunter DJ,O'Connell JR,Strachan DP,Wichmann HE,Borecki IB,van Duijn CM,Schadt EE,Thorsteinsdottir U,Peltonen L,Uitterlinden AG,Visscher PM,Chatterjee N,Loos RJ,Boehnke M,McCarthy MI,Ingelsson E,Lindgren CM,Abecasis GR,Stefansson K,Frayling TM,Hirschhorn JN

CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with caskin 1, a novel CASK-binding protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience22(11)4264-73(2002 Jun)
Tabuchi K,Biederer T,Butz S,Sudhof TC

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CASKIN1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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