SLC24A3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC24A3
Entrez Gene ID	57419
Full Name	solute carrier family 24 member 3
Synonyms	NCKX3
General protein information	Preferred Names solute carrier family 24 member 3 Names sodium/potassium/calcium exchanger 3 Na(+)/K(+)/Ca(2+)-exchange protein 3 sodium calcium exchanger solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20p11.23
Summary	Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008].
Disorder MIM:	609839

mRNA and Protein(s)

mRNA	Protein	Name
NM_020689.4	NP_065740.2	sodium/potassium/calcium exchanger 3 precursor
NM_020689.3	NP_065740.2	sodium/potassium/calcium exchanger 3 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SLC24A3	XP_003953735.1
Mus musculus (house mouse)	Slc24a3	NP_444425.1
Canis lupus familiaris (dog)	SLC24A3	XP_005634784.1
Rattus norvegicus (Norway rat)	Slc24a3	NP_445957.1
Gallus gallus (chicken)	SLC24A3	XP_004940202.1
Homo sapiens (human)	SLC24A3	NP_065740.2
	SLC24A3	XP_001090485.2
Drosophila melanogaster (fruit fly)	CG2893	NP_001015260.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010975	XP_001688244.1
Bos taurus (cattle)	SLC24A3	XP_002692183.1
Danio rerio (zebrafish)	slc24a3	XP_685302.4

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide association study of atypical psychosis.
Kanazawa T, Ikeda M, Glatt SJ, Tsutsumi A, Kikuyama H, Kawamura Y, Nishida N, Miyagawa T, Hashimoto R, Takeda M, Sasaki T, Tokunaga K, Koh J, Iwata N, Yoneda H
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics162B(7)679-86(2013 Oct)

Genome-wide association study of lung function decline in adults with and without asthma.
Imboden M, Bouzigon E, Curjuric I, Ramasamy A, Kumar A, Hancock DB, Wilk JB, Vonk JM, Thun GA, Siroux V, Nadif R, Monier F, Gonzalez JR, Wjst M, Heinrich J, Loehr LR, Franceschini N, North KE, Altm?ller J, Koppelman GH, Guerra S, Kronenberg F, Lathrop M, Moffatt MF, O'Connor GT, Strachan DP, Postma DS, London SJ, Schindler C, Kogevinas M, Kauffmann F, Jarvis DL, Demenais F, Probst-Hensch NM
The Journal of allergy and clinical immunology129(5)1218-28(2012 May)

Genome-wide association study of smoking behaviours in patients with COPD.
Siedlinski M, Cho MH, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Silverman EK, ,
Thorax66(10)894-902(2011 Oct)

Distinct expression of the calcium exchangers, NCKX3 and NCX1, and their regulation by steroid in the human endometrium during the menstrual cycle.
Yang H, Kim TH, Lee HH, Choi KC, Jeung EB
Reproductive sciences (Thousand Oaks, Calif.)18(6)577-85(2011 Jun)

Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels.
Cheng YC, Kao WH, Mitchell BD, O'Connell JR, Shen H, McArdle PF, Gibson Q, Ryan KA, Shuldiner AR, Pollin TI
Circulation. Cardiovascular genetics2(4)329-37(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NCKX3 is abundantly expressed within the human endometrium at the transcriptional and translational levels, and its level is regulated by steroid hormones (particularly estradiol) during the human menstrual cycle.
Title: Distinct expression of the calcium exchangers, NCKX3 and NCX1, and their regulation by steroid in the human endometrium during the menstrual cycle.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Plasma membrane ion transporter.Displayed K(+)-dependent Na(+)/Ca(2+) exchanger activity when assayed in heterologous expression systems, using digital imaging of fura-2 fluorescence, electrophysiology, or radioactive (45)Ca(2+) uptake.
Title: Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3.

The following SLC24A3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC24A3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15630	NM_020689.4 Latest version!	Homo sapiens solute carrier family 24 member 3 (SLC24A3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu15630	NM_020689.3	Homo sapiens solute carrier family 24 member 3 (SLC24A3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC24A3 ( NM_020689.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_065740.2 Homo sapiens solute carrier family 24 member 3 (SLC24A3), mRNA.

Price & Availability↑

CloneID	OHu15630
Clone ID Related Accession (Same CDS sequence)	NM_020689.4 , NM_020689.3
Accession Version	NM_020689.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	sodium/potassium/calcium exchanger 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL136090.12, AL049647.7, AL034425.9, AL139429.8, AL121830.25 and AL121761.5. On May 17, 2019 this sequence version replaced NM_020689.3. ##Evidence-Data-START## Transcript exon combination :: AF288087.1, AF169257.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000328041.11/ ENSP00000333519.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCGGCCGT CCGGCGACGA GGACCGCGCG CGTCGCCGCC GCCGCCGCCG CCGCCGGAGG 
GACCTTCTGC TGAGCCAGCT CTGCTTCCTG GCCTCGGTGG CGCTGCTGCT CTGGTCGCTG 
TCGAGCCTGC GAGAGCAGAA GGAGCTTGAC CTCATGGACC TCGTAGGGGA AGACAGAAAG 
TGGATGATGG CGAGGAAGCT GATGCAGGTG AACGACACTC TGACTTCCGA AGATGCCGGA 
CTCCGGAACA GCAAGAACTG CACCGAACCA GCCCTGCATG AATTCCCCAA TGACATCTTC 
ACAAACGAGG ATAGAAGACA AGGTGCGGTG GTCCTCCATG TGCTCTGTGC CATATACATG 
TTCTATGCGC TGGCCATTGT GTGTGATGAC TTCTTCGTCC CTTCCTTGGA AAAGATCTGT 
GAGCGCCTGC ACCTCAGTGA AGATGTGGCT GGGGCCACAT TCATGGCAGC GGGAAGTTCG 
GCCCCAGAGC TGTTCACATC GGTCATAGGG GTCTTCATCA CCAAAGGCGA TGTGGGAGTT 
GGCACCATCG TGGGCTCAGC GGTATTCAAC ATCCTGTGCA TCATTGGTGT CTGTGGGCTC 
TTTGCTGGGC AGGTTGTGGC TCTTTCCTCC TGGTGCCTGC TGAGGGATTC TATTTACTAC 
ACGCTGTCTG TGATCGCGCT CATCGTGTTT ATTTATGATG AAAAAGTTTC CTGGTGGGAG 
TCTTTAGTCC TTGTGCTGAT GTATCTTATC TACATTGTCA TCATGAAATA TAACGCTTGC 
ATACATCAGT GCTTTGAGAG GAGGACAAAA GGTGCCGGGA ACATGGTCAA CGGATTGGCC 
AACAATGCTG AAATTGATGA CAGCAGCAAC TGCGACGCAA CTGTGGTGCT ACTTAAGAAA 
GCAAATTTCC ACCGCAAAGC ATCAGTGATC ATGGTAGACG AGCTGCTGTC AGCCTACCCA 
CACCAGCTTT CCTTCTCTGA GGCTGGCCTT CGAATCATGA TAACCAGCCA CTTTCCCCCC 
AAGACCCGGC TCTCCATGGC CAGTCGCATG TTGATCAATG AGAGACAAAG ATTGATAAAC 
AGCAGGGCTT ATACCAACGG GGAATCTGAG GTGGCCATCA AAATCCCAAT TAAGCACACC 
GTGGAGAATG GGACAGGGCC CAGCAGTGCC CCAGACAGGG GCGTGAATGG GACACGGAGG 
GACGATGTTG TGGCTGAGGC TGGCAACGAA ACAGAGAATG AAAATGAGGA CAATGAGAAT 
GATGAGGAGG AAGAGGAGGA CGAGGATGAT GATGAAGGAC CGTACACACC ATTCGACACC 
CCCTCGGGTA AACTGGAAAC AGTGAAATGG GCGTTCACCT GGCCGCTGAG TTTCGTCTTA 
TACTTCACTG TACCCAACTG CAACAAGCCG CGCTGGGAGA AATGGTTCAT GGTGACGTTT 
GCTTCCTCCA CGCTGTGGAT CGCAGCCTTC TCCTACATGA TGGTGTGGAT GGTCACAATC 
ATTGGTTACA CCCTGGGGAT TCCTGACGTC ATCATGGGGA TCACCTTCCT GGCTGCTGGG 
ACCAGCGTGC CTGACTGCAT GGCCAGCCTC ATTGTGGCCA GACAAGGGAT GGGGGACATG 
GCTGTGTCCA ACTCCATTGG GAGCAACGTG TTTGACATCC TGATTGGCCT CGGTCTCCCC 
TGGGCTCTGC AGACCCTGGC TGTGGATTAC GGATCCTACA TCCGGCTGAA TAGCAGGGGG 
CTGATCTACT CCGTAGGCTT GCTCCTGGCC TCTGTTTTTG TCACGGTGTT CGGCGTCCAC 
CTGAACAAGT GGCAGCTGGA CAAGAAGCTG GGCTGTGGGT GCCTCCTCCT GTATGGTGTG 
TTCCTGTGCT TCTCCATCAT GACTGAGTTC AACGTGTTCA CCTTTGTGAA CCTGCCCATG 
TGCGGGGACC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065740.2
CDS	202..2136
Translation	MRPSGDEDRARRRRRRRRRRDLLLSQLCFLASVALLLWSLSSLREQKELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMTEFNVFTFVNLPMCGDH

Target ORF information:

RefSeq Version	NM_020689.4
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 24 member 3 (SLC24A3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020689.4

ORF Insert Sequence:

ATGCGGCCGT CCGGCGACGA GGACCGCGCG CGTCGCCGCC GCCGCCGCCG CCGCCGGAGG 
GACCTTCTGC TGAGCCAGCT CTGCTTCCTG GCCTCGGTGG CGCTGCTGCT CTGGTCGCTG 
TCGAGCCTGC GAGAGCAGAA GGAGCTTGAC CTCATGGACC TCGTAGGGGA AGACAGAAAG 
TGGATGATGG CGAGGAAGCT GATGCAGGTG AACGACACTC TGACTTCCGA AGATGCCGGA 
CTCCGGAACA GCAAGAACTG CACCGAACCA GCCCTGCATG AATTCCCCAA TGACATCTTC 
ACAAACGAGG ATAGAAGACA AGGTGCGGTG GTCCTCCATG TGCTCTGTGC CATATACATG 
TTCTATGCGC TGGCCATTGT GTGTGATGAC TTCTTCGTCC CTTCCTTGGA AAAGATCTGT 
GAGCGCCTGC ACCTCAGTGA AGATGTGGCT GGGGCCACAT TCATGGCAGC GGGAAGTTCG 
GCCCCAGAGC TGTTCACATC GGTCATAGGG GTCTTCATCA CCAAAGGCGA TGTGGGAGTT 
GGCACCATCG TGGGCTCAGC GGTATTCAAC ATCCTGTGCA TCATTGGTGT CTGTGGGCTC 
TTTGCTGGGC AGGTTGTGGC TCTTTCCTCC TGGTGCCTGC TGAGGGATTC TATTTACTAC 
ACGCTGTCTG TGATCGCGCT CATCGTGTTT ATTTATGATG AAAAAGTTTC CTGGTGGGAG 
TCTTTAGTCC TTGTGCTGAT GTATCTTATC TACATTGTCA TCATGAAATA TAACGCTTGC 
ATACATCAGT GCTTTGAGAG GAGGACAAAA GGTGCCGGGA ACATGGTCAA CGGATTGGCC 
AACAATGCTG AAATTGATGA CAGCAGCAAC TGCGACGCAA CTGTGGTGCT ACTTAAGAAA 
GCAAATTTCC ACCGCAAAGC ATCAGTGATC ATGGTAGACG AGCTGCTGTC AGCCTACCCA 
CACCAGCTTT CCTTCTCTGA GGCTGGCCTT CGAATCATGA TAACCAGCCA CTTTCCCCCC 
AAGACCCGGC TCTCCATGGC CAGTCGCATG TTGATCAATG AGAGACAAAG ATTGATAAAC 
AGCAGGGCTT ATACCAACGG GGAATCTGAG GTGGCCATCA AAATCCCAAT TAAGCACACC 
GTGGAGAATG GGACAGGGCC CAGCAGTGCC CCAGACAGGG GCGTGAATGG GACACGGAGG 
GACGATGTTG TGGCTGAGGC TGGCAACGAA ACAGAGAATG AAAATGAGGA CAATGAGAAT 
GATGAGGAGG AAGAGGAGGA CGAGGATGAT GATGAAGGAC CGTACACACC ATTCGACACC 
CCCTCGGGTA AACTGGAAAC AGTGAAATGG GCGTTCACCT GGCCGCTGAG TTTCGTCTTA 
TACTTCACTG TACCCAACTG CAACAAGCCG CGCTGGGAGA AATGGTTCAT GGTGACGTTT 
GCTTCCTCCA CGCTGTGGAT CGCAGCCTTC TCCTACATGA TGGTGTGGAT GGTCACAATC 
ATTGGTTACA CCCTGGGGAT TCCTGACGTC ATCATGGGGA TCACCTTCCT GGCTGCTGGG 
ACCAGCGTGC CTGACTGCAT GGCCAGCCTC ATTGTGGCCA GACAAGGGAT GGGGGACATG 
GCTGTGTCCA ACTCCATTGG GAGCAACGTG TTTGACATCC TGATTGGCCT CGGTCTCCCC 
TGGGCTCTGC AGACCCTGGC TGTGGATTAC GGATCCTACA TCCGGCTGAA TAGCAGGGGG 
CTGATCTACT CCGTAGGCTT GCTCCTGGCC TCTGTTTTTG TCACGGTGTT CGGCGTCCAC 
CTGAACAAGT GGCAGCTGGA CAAGAAGCTG GGCTGTGGGT GCCTCCTCCT GTATGGTGTG 
TTCCTGTGCT TCTCCATCAT GACTGAGTTC AACGTGTTCA CCTTTGTGAA CCTGCCCATG 
TGCGGGGACC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC24A3 ( NM_020689.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_065740.2 Homo sapiens solute carrier family 24 member 3 (SLC24A3), mRNA.

Price & Availability↑

CloneID	OHu15630
Clone ID Related Accession (Same CDS sequence)	NM_020689.4 , NM_020689.3
Accession Version	NM_020689.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	sodium/potassium/calcium exchanger 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF288087.1. On Jun 10, 2003 this sequence version replaced NM_020689.2. ##Evidence-Data-START## Transcript exon combination :: AF288087.1, AF169257.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END##

ATGCGGCCGT CCGGCGACGA GGACCGCGCG CGTCGCCGCC GCCGCCGCCG CCGCCGGAGG 
GACCTTCTGC TGAGCCAGCT CTGCTTCCTG GCCTCGGTGG CGCTGCTGCT CTGGTCGCTG 
TCGAGCCTGC GAGAGCAGAA GGAGCTTGAC CTCATGGACC TCGTAGGGGA AGACAGAAAG 
TGGATGATGG CGAGGAAGCT GATGCAGGTG AACGACACTC TGACTTCCGA AGATGCCGGA 
CTCCGGAACA GCAAGAACTG CACCGAACCA GCCCTGCATG AATTCCCCAA TGACATCTTC 
ACAAACGAGG ATAGAAGACA AGGTGCGGTG GTCCTCCATG TGCTCTGTGC CATATACATG 
TTCTATGCGC TGGCCATTGT GTGTGATGAC TTCTTCGTCC CTTCCTTGGA AAAGATCTGT 
GAGCGCCTGC ACCTCAGTGA AGATGTGGCT GGGGCCACAT TCATGGCAGC GGGAAGTTCG 
GCCCCAGAGC TGTTCACATC GGTCATAGGG GTCTTCATCA CCAAAGGCGA TGTGGGAGTT 
GGCACCATCG TGGGCTCAGC GGTATTCAAC ATCCTGTGCA TCATTGGTGT CTGTGGGCTC 
TTTGCTGGGC AGGTTGTGGC TCTTTCCTCC TGGTGCCTGC TGAGGGATTC TATTTACTAC 
ACGCTGTCTG TGATCGCGCT CATCGTGTTT ATTTATGATG AAAAAGTTTC CTGGTGGGAG 
TCTTTAGTCC TTGTGCTGAT GTATCTTATC TACATTGTCA TCATGAAATA TAACGCTTGC 
ATACATCAGT GCTTTGAGAG GAGGACAAAA GGTGCCGGGA ACATGGTCAA CGGATTGGCC 
AACAATGCTG AAATTGATGA CAGCAGCAAC TGCGACGCAA CTGTGGTGCT ACTTAAGAAA 
GCAAATTTCC ACCGCAAAGC ATCAGTGATC ATGGTAGACG AGCTGCTGTC AGCCTACCCA 
CACCAGCTTT CCTTCTCTGA GGCTGGCCTT CGAATCATGA TAACCAGCCA CTTTCCCCCC 
AAGACCCGGC TCTCCATGGC CAGTCGCATG TTGATCAATG AGAGACAAAG ATTGATAAAC 
AGCAGGGCTT ATACCAACGG GGAATCTGAG GTGGCCATCA AAATCCCAAT TAAGCACACC 
GTGGAGAATG GGACAGGGCC CAGCAGTGCC CCAGACAGGG GCGTGAATGG GACACGGAGG 
GACGATGTTG TGGCTGAGGC TGGCAACGAA ACAGAGAATG AAAATGAGGA CAATGAGAAT 
GATGAGGAGG AAGAGGAGGA CGAGGATGAT GATGAAGGAC CGTACACACC ATTCGACACC 
CCCTCGGGTA AACTGGAAAC AGTGAAATGG GCGTTCACCT GGCCGCTGAG TTTCGTCTTA 
TACTTCACTG TACCCAACTG CAACAAGCCG CGCTGGGAGA AATGGTTCAT GGTGACGTTT 
GCTTCCTCCA CGCTGTGGAT CGCAGCCTTC TCCTACATGA TGGTGTGGAT GGTCACAATC 
ATTGGTTACA CCCTGGGGAT TCCTGACGTC ATCATGGGGA TCACCTTCCT GGCTGCTGGG 
ACCAGCGTGC CTGACTGCAT GGCCAGCCTC ATTGTGGCCA GACAAGGGAT GGGGGACATG 
GCTGTGTCCA ACTCCATTGG GAGCAACGTG TTTGACATCC TGATTGGCCT CGGTCTCCCC 
TGGGCTCTGC AGACCCTGGC TGTGGATTAC GGATCCTACA TCCGGCTGAA TAGCAGGGGG 
CTGATCTACT CCGTAGGCTT GCTCCTGGCC TCTGTTTTTG TCACGGTGTT CGGCGTCCAC 
CTGAACAAGT GGCAGCTGGA CAAGAAGCTG GGCTGTGGGT GCCTCCTCCT GTATGGTGTG 
TTCCTGTGCT TCTCCATCAT GACTGAGTTC AACGTGTTCA CCTTTGTGAA CCTGCCCATG 
TGCGGGGACC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065740.2
CDS	198..2132
Translation	MRPSGDEDRARRRRRRRRRRDLLLSQLCFLASVALLLWSLSSLREQKELDLMDLVGEDRKWMMARKLMQVNDTLTSEDAGLRNSKNCTEPALHEFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIMVDELLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYTNGESEVAIKIPIKHTVENGTGPSSAPDRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMTEFNVFTFVNLPMCGDH

Target ORF information:

RefSeq Version	NM_020689.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 24 member 3 (SLC24A3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020689.3

ORF Insert Sequence:

ATGCGGCCGT CCGGCGACGA GGACCGCGCG CGTCGCCGCC GCCGCCGCCG CCGCCGGAGG 
GACCTTCTGC TGAGCCAGCT CTGCTTCCTG GCCTCGGTGG CGCTGCTGCT CTGGTCGCTG 
TCGAGCCTGC GAGAGCAGAA GGAGCTTGAC CTCATGGACC TCGTAGGGGA AGACAGAAAG 
TGGATGATGG CGAGGAAGCT GATGCAGGTG AACGACACTC TGACTTCCGA AGATGCCGGA 
CTCCGGAACA GCAAGAACTG CACCGAACCA GCCCTGCATG AATTCCCCAA TGACATCTTC 
ACAAACGAGG ATAGAAGACA AGGTGCGGTG GTCCTCCATG TGCTCTGTGC CATATACATG 
TTCTATGCGC TGGCCATTGT GTGTGATGAC TTCTTCGTCC CTTCCTTGGA AAAGATCTGT 
GAGCGCCTGC ACCTCAGTGA AGATGTGGCT GGGGCCACAT TCATGGCAGC GGGAAGTTCG 
GCCCCAGAGC TGTTCACATC GGTCATAGGG GTCTTCATCA CCAAAGGCGA TGTGGGAGTT 
GGCACCATCG TGGGCTCAGC GGTATTCAAC ATCCTGTGCA TCATTGGTGT CTGTGGGCTC 
TTTGCTGGGC AGGTTGTGGC TCTTTCCTCC TGGTGCCTGC TGAGGGATTC TATTTACTAC 
ACGCTGTCTG TGATCGCGCT CATCGTGTTT ATTTATGATG AAAAAGTTTC CTGGTGGGAG 
TCTTTAGTCC TTGTGCTGAT GTATCTTATC TACATTGTCA TCATGAAATA TAACGCTTGC 
ATACATCAGT GCTTTGAGAG GAGGACAAAA GGTGCCGGGA ACATGGTCAA CGGATTGGCC 
AACAATGCTG AAATTGATGA CAGCAGCAAC TGCGACGCAA CTGTGGTGCT ACTTAAGAAA 
GCAAATTTCC ACCGCAAAGC ATCAGTGATC ATGGTAGACG AGCTGCTGTC AGCCTACCCA 
CACCAGCTTT CCTTCTCTGA GGCTGGCCTT CGAATCATGA TAACCAGCCA CTTTCCCCCC 
AAGACCCGGC TCTCCATGGC CAGTCGCATG TTGATCAATG AGAGACAAAG ATTGATAAAC 
AGCAGGGCTT ATACCAACGG GGAATCTGAG GTGGCCATCA AAATCCCAAT TAAGCACACC 
GTGGAGAATG GGACAGGGCC CAGCAGTGCC CCAGACAGGG GCGTGAATGG GACACGGAGG 
GACGATGTTG TGGCTGAGGC TGGCAACGAA ACAGAGAATG AAAATGAGGA CAATGAGAAT 
GATGAGGAGG AAGAGGAGGA CGAGGATGAT GATGAAGGAC CGTACACACC ATTCGACACC 
CCCTCGGGTA AACTGGAAAC AGTGAAATGG GCGTTCACCT GGCCGCTGAG TTTCGTCTTA 
TACTTCACTG TACCCAACTG CAACAAGCCG CGCTGGGAGA AATGGTTCAT GGTGACGTTT 
GCTTCCTCCA CGCTGTGGAT CGCAGCCTTC TCCTACATGA TGGTGTGGAT GGTCACAATC 
ATTGGTTACA CCCTGGGGAT TCCTGACGTC ATCATGGGGA TCACCTTCCT GGCTGCTGGG 
ACCAGCGTGC CTGACTGCAT GGCCAGCCTC ATTGTGGCCA GACAAGGGAT GGGGGACATG 
GCTGTGTCCA ACTCCATTGG GAGCAACGTG TTTGACATCC TGATTGGCCT CGGTCTCCCC 
TGGGCTCTGC AGACCCTGGC TGTGGATTAC GGATCCTACA TCCGGCTGAA TAGCAGGGGG 
CTGATCTACT CCGTAGGCTT GCTCCTGGCC TCTGTTTTTG TCACGGTGTT CGGCGTCCAC 
CTGAACAAGT GGCAGCTGGA CAAGAAGCTG GGCTGTGGGT GCCTCCTCCT GTATGGTGTG 
TTCCTGTGCT TCTCCATCAT GACTGAGTTC AACGTGTTCA CCTTTGTGAA CCTGCCCATG 
TGCGGGGACC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide association study of atypical psychosis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics162B(7)679-86(2013 Oct)
Kanazawa T,Ikeda M,Glatt SJ,Tsutsumi A,Kikuyama H,Kawamura Y,Nishida N,Miyagawa T,Hashimoto R,Takeda M,Sasaki T,Tokunaga K,Koh J,Iwata N,Yoneda H

Genome-wide association study of lung function decline in adults with and without asthma.
The Journal of allergy and clinical immunology129(5)1218-28(2012 May)
Imboden M,Bouzigon E,Curjuric I,Ramasamy A,Kumar A,Hancock DB,Wilk JB,Vonk JM,Thun GA,Siroux V,Nadif R,Monier F,Gonzalez JR,Wjst M,Heinrich J,Loehr LR,Franceschini N,North KE,Altm?ller J,Koppelman GH,Guerra S,Kronenberg F,Lathrop M,Moffatt MF,O'Connor GT,Strachan DP,Postma DS,London SJ,Schindler C,Kogevinas M,Kauffmann F,Jarvis DL,Demenais F,Probst-Hensch NM

Genome-wide association study of smoking behaviours in patients with COPD.
Thorax66(10)894-902(2011 Oct)
Siedlinski M,Cho MH,Bakke P,Gulsvik A,Lomas DA,Anderson W,Kong X,Rennard SI,Beaty TH,Hokanson JE,Crapo JD,Silverman EK,,

Distinct expression of the calcium exchangers, NCKX3 and NCX1, and their regulation by steroid in the human endometrium during the menstrual cycle.
Reproductive sciences (Thousand Oaks, Calif.)18(6)577-85(2011 Jun)
Yang H,Kim TH,Lee HH,Choi KC,Jeung EB

Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels.
Circulation. Cardiovascular genetics2(4)329-37(2009 Aug)
Cheng YC,Kao WH,Mitchell BD,O'Connell JR,Shen H,McArdle PF,Gibson Q,Ryan KA,Shuldiner AR,Pollin TI

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SLC24A3 cDNA ORF clone, Homo sapiens(human)

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