Gene Symbol | LIMS2 |
Entrez Gene ID | 55679 |
Full Name | LIM zinc finger domain containing 2 |
Synonyms | LGMD2W,PINCH-2,PINCH2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. |
Disorder MIM: | |
Disorder Html: | Muscular dystrophy, limb-girdle, type 2W, 616827 (3) |