KRBOX4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRBOX4
Entrez Gene ID	55634
Full Name	KRAB box domain containing 4
Synonyms	ZNF673
General protein information	Preferred Names KRAB box domain containing 4 Names KRAB domain-containing protein 4 KRAB box domain-containing protein 4 putative zinc finger transcription factor zinc finger family member 673 zinc finger protein 673
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp11.3
Summary	This encodes a zinc finger protein with an N-terminal KRAB (Kruppel-associated) domain found in transcriptional repressors. This gene is located in a region of the X chromosome thought to be involved in nonsyndromic X-linked cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
Disorder MIM:	300585

mRNA and Protein(s)

mRNA	Protein	Name
NM_017776.2	NP_060246.2	KRAB domain-containing protein 4 isoform 2
NM_001129898.1	NP_001123370.1	KRAB domain-containing protein 4 isoform 1
NM_001129899.1	NP_001123371.1	KRAB domain-containing protein 4 isoform 3
NM_001129900.1	NP_001123372.1	KRAB domain-containing protein 4 isoform 4
NM_001129898.2	NP_001123370.1	KRAB domain-containing protein 4 isoform 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ZNF673	XP_001148494.2
	ZNF673	XP_002806254.1
Homo sapiens (human)	KRBOX4	NP_001123370.1

Gene Ontology
Bibliography

Related articles in PubMed

ZNF674: a new kruppel-associated box-containing zinc-finger gene involved in nonsyndromic X-linked mental retardation.
Lugtenberg D, Yntema HG, Banning MJ, Oudakker AR, Firth HV, Willatt L, Raynaud M, Kleefstra T, Fryns JP, Ropers HH, Chelly J, Moraine C, Gecz J, van Reeuwijk J, Nabuurs SB, de Vries BB, Hamel BC, de Brouwer AP, van Bokhoven H
American journal of human genetics78(2)265-78(2006 Feb)

The DNA sequence of the human X chromosome.
Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Wen G, Jones MC, Hurles ME, Andrews TD, Scott CE, Searle S, Ramser J, Whittaker A, Deadman R, Carter NP, Hunt SE, Chen R, Cree A, Gunaratne P, Havlak P, Hodgson A, Metzker ML, Richards S, Scott G, Steffen D, Sodergren E, Wheeler DA, Worley KC, Ainscough R, Ambrose KD, Ansari-Lari MA, Aradhya S, Ashwell RI, Babbage AK, Bagguley CL, Ballabio A, Banerjee R, Barker GE, Barlow KF, Barrett IP, Bates KN, Beare DM, Beasley H, Beasley O, Beck A, Bethel G, Blechschmidt K, Brady N, Bray-Allen S, Bridgeman AM, Brown AJ, Brown MJ, Bonnin D, Bruford EA, Buhay C, Burch P, Burford D, Burgess J, Burrill W, Burton J, Bye JM, Carder C, Carrel L, Chako J, Chapman JC, Chavez D, Chen E, Chen G, Chen Y, Chen Z, Chinault C, Ciccodicola A, Clark SY, Clarke G, Clee CM, Clegg S, Clerc-Blankenburg K, Clifford K, Cobley V, Cole CG, Conquer JS, Corby N, Connor RE, David R, Davies J, Davis C, Davis J, Delgado O, Deshazo D, Dhami P, Ding Y, Dinh H, Dodsworth S, Draper H, Dugan-Rocha S, Dunham A, Dunn M, Durbin KJ, Dutta I, Eades T, Ellwood M, Emery-Cohen A, Errington H, Evans KL, Faulkner L, Francis F, Frankland J, Fraser AE, Galgoczy P, Gilbert J, Gill R, Gl?ckner G, Gregory SG, Gribble S, Griffiths C, Grocock R, Gu Y, Gwilliam R, Hamilton C, Hart EA, Hawes A, Heath PD, Heitmann K, Hennig S, Hernandez J, Hinzmann B, Ho S, Hoffs M, Howden PJ, Huckle EJ, Hume J, Hunt PJ, Hunt AR, Isherwood J, Jacob L, Johnson D, Jones S, de Jong PJ, Joseph SS, Keenan S, Kelly S, Kershaw JK, Khan Z, Kioschis P, Klages S, Knights AJ, Kosiura A, Kovar-Smith C, Laird GK, Langford C, Lawlor S, Leversha M, Lewis L, Liu W, Lloyd C, Lloyd DM, Loulseged H, Loveland JE, Lovell JD, Lozado R, Lu J, Lyne R, Ma J, Maheshwari M, Matthews LH, McDowall J, McLaren S, McMurray A, Meidl P, Meitinger T, Milne S, Miner G, Mistry SL, Morgan M, Morris S, M?ller I, Mullikin JC, Nguyen N, Nordsiek G, Nyakatura G, O'Dell CN, Okwuonu G, Palmer S, Pandian R, Parker D, Parrish J, Pasternak S, Patel D, Pearce AV, Pearson DM, Pelan SE, Perez L, Porter KM, Ramsey Y, Reichwald K, Rhodes S, Ridler KA, Schlessinger D, Schueler MG, Sehra HK, Shaw-Smith C, Shen H, Sheridan EM, Shownkeen R, Skuce CD, Smith ML, Sotheran EC, Steingruber HE, Steward CA, Storey R, Swann RM, Swarbreck D, Tabor PE, Taudien S, Taylor T, Teague B, Thomas K, Thorpe A, Timms K, Tracey A, Trevanion S, Tromans AC, d'Urso M, Verduzco D, Villasana D, Waldron L, Wall M, Wang Q, Warren J, Warry GL, Wei X, West A, Whitehead SL, Whiteley MN, Wilkinson JE, Willey DL, Williams G, Williams L, Williamson A, Williamson H, Wilming L, Woodmansey RL, Wray PW, Yen J, Zhang J, Zhou J, Zoghbi H, Zorilla S, Buck D, Reinhardt R, Poustka A, Rosenthal A, Lehrach H, Meindl A, Minx PJ, Hillier LW, Willard HF, Wilson RK, Waterston RH, Rice CM, Vaudin M, Coulson A, Nelson DL, Weinstock G, Sulston JE, Durbin R, Hubbard T, Gibbs RA, Beck S, Rogers J, Bentley DR
Nature434(7031)325-37(2005 Mar)

An integrated, functionally annotated gene map of the DXS8026-ELK1 interval on human Xp11.3-Xp11.23: potential hotspot for neurogenetic disorders.
Thiselton DL, McDowall J, Brandau O, Ramser J, d'Esposito F, Bhattacharya SS, Ross MT, Hardcastle AJ, Meindl A
Genomics79(4)560-72(2002 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KRBOX4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRBOX4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06946	NM_001129898.2 Latest version!	Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu06949	NM_001129899.1 Latest version!	Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu06952	NM_001129900.1 Latest version!	Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu18143	NM_017776.2 Latest version!	Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu06946	NM_001129898.1	Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRBOX4 ( NM_001129898.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001123370.1 Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06946
Clone ID Related Accession (Same CDS sequence)	NM_001129898.1 , NM_001129898.2
Accession Version	NM_001129898.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	KRAB domain-containing protein 4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA877282.1, AK096413.1, AL139811.30 and AK000351.1. Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.252853.1, SRR1803616.198573.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCATGT CCCAGGAATC ATTGACCTTC AAGGACGTGT TTGTGGACTT CACCCTGGAG 
GAGTGGCAGC AACTGGACTC TGCCCAGAAG AACCTCTACA GGGATGTCAT GCTTGAGAAC 
TACAGCCACC TGGTGTCCGT GGGGTATCTA GTTGCGAAGC CAGATGTGAT CTTCAGGTTG 
GGACCAGGTG AAGAGTCCTG GATGGCAGAT GGGGGGACCC CGGTACGGAC CTGTGCAGGT 
GAGGACAGGC CAGAAGTCTG GCAAGTTGAT GAGCAGATAG ATCACTACAA GGAAAGCCAA 
GACAAACTTC CTTGGCAAGC TGCATTCATA GGCAAGGAAA CACTGAAGGA TGAAAGCGGT 
CAAGAATCCA GAACATGTAG AAAAAGCATT TATCTGAGCA CAGAATTTGA TTCTGTAAGG 
CAAAGACTCC CTAAATATTA TTCGTGGGAA AAGGCATTCA AAACATCATT TAAACTTTCT 
TGGTCAAAAT GGAAGCTATG TAAGAAAGAA AGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001123370.1
CDS	300..815
Translation	MAMSQESLTFKDVFVDFTLEEWQQLDSAQKNLYRDVMLENYSHLVSVGYLVAKPDVIFRLGPGEESWMADGGTPVRTCAGEDRPEVWQVDEQIDHYKESQDKLPWQAAFIGKETLKDESGQESRTCRKSIYLSTEFDSVRQRLPKYYSWEKAFKTSFKLSWSKWKLCKKER

Target ORF information:

RefSeq Version	NM_001129898.1
Organism	Homo sapiens(human)
Definition	Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001129898.1

ORF Insert Sequence:

ATGGCCATGT CCCAGGAATC ATTGACCTTC AAGGACGTGT TTGTGGACTT CACCCTGGAG 
GAGTGGCAGC AACTGGACTC TGCCCAGAAG AACCTCTACA GGGATGTCAT GCTTGAGAAC 
TACAGCCACC TGGTGTCCGT GGGGTATCTA GTTGCGAAGC CAGATGTGAT CTTCAGGTTG 
GGACCAGGTG AAGAGTCCTG GATGGCAGAT GGGGGGACCC CGGTACGGAC CTGTGCAGGT 
GAGGACAGGC CAGAAGTCTG GCAAGTTGAT GAGCAGATAG ATCACTACAA GGAAAGCCAA 
GACAAACTTC CTTGGCAAGC TGCATTCATA GGCAAGGAAA CACTGAAGGA TGAAAGCGGT 
CAAGAATCCA GAACATGTAG AAAAAGCATT TATCTGAGCA CAGAATTTGA TTCTGTAAGG 
CAAAGACTCC CTAAATATTA TTCGTGGGAA AAGGCATTCA AAACATCATT TAAACTTTCT 
TGGTCAAAAT GGAAGCTATG TAAGAAAGAA AGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRBOX4 ( NM_001129898.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001123370.1 Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu06946
Clone ID Related Accession (Same CDS sequence)	NM_001129898.1 , NM_001129898.2
Accession Version	NM_001129898.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-30
Organism	Homo sapiens(human)
Product	KRAB domain-containing protein 4 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096413.1, AL139811.30 and AK000351.1. On Nov 23, 2018 this sequence version replaced NM_001129898.1. Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK096413.1, SRR1803614.35572.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000344302.9/ ENSP00000345797.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCATGT CCCAGGAATC ATTGACCTTC AAGGACGTGT TTGTGGACTT CACCCTGGAG 
GAGTGGCAGC AACTGGACTC TGCCCAGAAG AACCTCTACA GGGATGTCAT GCTTGAGAAC 
TACAGCCACC TGGTGTCCGT GGGGTATCTA GTTGCGAAGC CAGATGTGAT CTTCAGGTTG 
GGACCAGGTG AAGAGTCCTG GATGGCAGAT GGGGGGACCC CGGTACGGAC CTGTGCAGGT 
GAGGACAGGC CAGAAGTCTG GCAAGTTGAT GAGCAGATAG ATCACTACAA GGAAAGCCAA 
GACAAACTTC CTTGGCAAGC TGCATTCATA GGCAAGGAAA CACTGAAGGA TGAAAGCGGT 
CAAGAATCCA GAACATGTAG AAAAAGCATT TATCTGAGCA CAGAATTTGA TTCTGTAAGG 
CAAAGACTCC CTAAATATTA TTCGTGGGAA AAGGCATTCA AAACATCATT TAAACTTTCT 
TGGTCAAAAT GGAAGCTATG TAAGAAAGAA AGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001123370.1
CDS	192..707
Translation	MAMSQESLTFKDVFVDFTLEEWQQLDSAQKNLYRDVMLENYSHLVSVGYLVAKPDVIFRLGPGEESWMADGGTPVRTCAGEDRPEVWQVDEQIDHYKESQDKLPWQAAFIGKETLKDESGQESRTCRKSIYLSTEFDSVRQRLPKYYSWEKAFKTSFKLSWSKWKLCKKER

Target ORF information:

RefSeq Version	NM_001129898.2
Organism	Homo sapiens(human)
Definition	Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001129898.2

ORF Insert Sequence:

ATGGCCATGT CCCAGGAATC ATTGACCTTC AAGGACGTGT TTGTGGACTT CACCCTGGAG 
GAGTGGCAGC AACTGGACTC TGCCCAGAAG AACCTCTACA GGGATGTCAT GCTTGAGAAC 
TACAGCCACC TGGTGTCCGT GGGGTATCTA GTTGCGAAGC CAGATGTGAT CTTCAGGTTG 
GGACCAGGTG AAGAGTCCTG GATGGCAGAT GGGGGGACCC CGGTACGGAC CTGTGCAGGT 
GAGGACAGGC CAGAAGTCTG GCAAGTTGAT GAGCAGATAG ATCACTACAA GGAAAGCCAA 
GACAAACTTC CTTGGCAAGC TGCATTCATA GGCAAGGAAA CACTGAAGGA TGAAAGCGGT 
CAAGAATCCA GAACATGTAG AAAAAGCATT TATCTGAGCA CAGAATTTGA TTCTGTAAGG 
CAAAGACTCC CTAAATATTA TTCGTGGGAA AAGGCATTCA AAACATCATT TAAACTTTCT 
TGGTCAAAAT GGAAGCTATG TAAGAAAGAA AGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRBOX4 ( NM_001129899.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001123371.1 Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu06949
Clone ID Related Accession (Same CDS sequence)	NM_001129899.1
Accession Version	NM_001129899.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 297bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	KRAB domain-containing protein 4 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA877282.1, DA152034.1, AL139811.30 and AK000351.1. Transcript Variant: This variant (3) contains a different segment in the 3' coding region that shifts the reading frame, compared to variant 1. The resulting protein (isoform 3) has a distinct C-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.274462.1, SRR1660809.144215.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCATGT CCCAGGAATC ATTGACCTTC AAGGACGTGT TTGTGGACTT CACCCTGGAG 
GAGTGGCAGC AACTGGACTC TGCCCAGAAG AACCTCTACA GGGATGTCAT GCTTGAGAAC 
TACAGCCACC TGGTGTCCGT GGGGTATCTA GTTGCGAAGC CAGATGTGAT CTTCAGGTTG 
GGACCAGGTG AAGAGTCCTG GATGGCAGAT GGGGGGACCC CGGTACGGAC CTGTGCAGGT 
GAGGACAGGC CAGATGTATC CATTTTTGCC TCATGTATTT TGAAGTGCTG TTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001123371.1
CDS	300..596
Translation	MAMSQESLTFKDVFVDFTLEEWQQLDSAQKNLYRDVMLENYSHLVSVGYLVAKPDVIFRLGPGEESWMADGGTPVRTCAGEDRPDVSIFASCILKCCY

Target ORF information:

RefSeq Version	NM_001129899.1
Organism	Homo sapiens(human)
Definition	Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001129899.1

ORF Insert Sequence:

ATGGCCATGT CCCAGGAATC ATTGACCTTC AAGGACGTGT TTGTGGACTT CACCCTGGAG 
GAGTGGCAGC AACTGGACTC TGCCCAGAAG AACCTCTACA GGGATGTCAT GCTTGAGAAC 
TACAGCCACC TGGTGTCCGT GGGGTATCTA GTTGCGAAGC CAGATGTGAT CTTCAGGTTG 
GGACCAGGTG AAGAGTCCTG GATGGCAGAT GGGGGGACCC CGGTACGGAC CTGTGCAGGT 
GAGGACAGGC CAGATGTATC CATTTTTGCC TCATGTATTT TGAAGTGCTG TTATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRBOX4 ( NM_001129900.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001123372.1 Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu06952
Clone ID Related Accession (Same CDS sequence)	NM_001129900.1
Accession Version	NM_001129900.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 282bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	KRAB domain-containing protein 4 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA877282.1, DA631861.1, AL139811.30 and AK000351.1. Transcript Variant: This variant (4) uses a different splice site and contains a different segment in the 3' coding region that shifts the reading frame, compared to variant 1. The resulting protein (isoform 4) has a distinct C-terminus, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.216047.1, SRR1803615.17794.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCATGT CCCAGGAATC ATTGACCTTC AAGGACGTGT TTGTGGACTT CACCCTGGAG 
GAGTGGCAGC AACTGGACTC TGCCCAGAAG AACCTCTACA GGGATGTCAT GCTTGAGAAC 
TACAGCCACC TGGTGTCCGT GGGGTATCTA GTTGCGAAGC CAGATGTGAT CTTCAGGTTG 
GGACCAGGTG AAGAGTCCTG GATGGCAGAT GGGGGGACCC CGGTACGGAC CTGTGCAGAT 
GTATCCATTT TTGCCTCATG TATTTTGAAG TGCTGTTATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001123372.1
CDS	300..581
Translation	MAMSQESLTFKDVFVDFTLEEWQQLDSAQKNLYRDVMLENYSHLVSVGYLVAKPDVIFRLGPGEESWMADGGTPVRTCADVSIFASCILKCCY

Target ORF information:

RefSeq Version	NM_001129900.1
Organism	Homo sapiens(human)
Definition	Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001129900.1

ORF Insert Sequence:

ATGGCCATGT CCCAGGAATC ATTGACCTTC AAGGACGTGT TTGTGGACTT CACCCTGGAG 
GAGTGGCAGC AACTGGACTC TGCCCAGAAG AACCTCTACA GGGATGTCAT GCTTGAGAAC 
TACAGCCACC TGGTGTCCGT GGGGTATCTA GTTGCGAAGC CAGATGTGAT CTTCAGGTTG 
GGACCAGGTG AAGAGTCCTG GATGGCAGAT GGGGGGACCC CGGTACGGAC CTGTGCAGAT 
GTATCCATTT TTGCCTCATG TATTTTGAAG TGCTGTTATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRBOX4 ( NM_017776.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_060246.2 Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu18143
Clone ID Related Accession (Same CDS sequence)	NM_017776.2
Accession Version	NM_017776.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 501bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	KRAB domain-containing protein 4 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA877282.1, AK000351.1, BC012569.1 and AL139811.30. This sequence is a reference standard in the RefSeqGene project. On Jul 10, 2008 this sequence version replaced NM_017776.1. Transcript Variant: This variant (2) uses a different splice site in the CDS, compared to variant 1. The resulting protein (isoform 2) is shorter by 5 aa when it is compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK000351.1, SRR1660809.150319.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCATGT CCCAGGAATC ATTGACCTTC AAGGACGTGT TTGTGGACTT CACCCTGGAG 
GAGTGGCAGC AACTGGACTC TGCCCAGAAG AACCTCTACA GGGATGTCAT GCTTGAGAAC 
TACAGCCACC TGGTGTCCGT GGGGTATCTA GTTGCGAAGC CAGATGTGAT CTTCAGGTTG 
GGACCAGGTG AAGAGTCCTG GATGGCAGAT GGGGGGACCC CGGTACGGAC CTGTGCAGAA 
GTCTGGCAAG TTGATGAGCA GATAGATCAC TACAAGGAAA GCCAAGACAA ACTTCCTTGG 
CAAGCTGCAT TCATAGGCAA GGAAACACTG AAGGATGAAA GCGGTCAAGA ATCCAGAACA 
TGTAGAAAAA GCATTTATCT GAGCACAGAA TTTGATTCTG TAAGGCAAAG ACTCCCTAAA 
TATTATTCGT GGGAAAAGGC ATTCAAAACA TCATTTAAAC TTTCTTGGTC AAAATGGAAG 
CTATGTAAGA AAGAAAGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060246.2
CDS	300..800
Translation	MAMSQESLTFKDVFVDFTLEEWQQLDSAQKNLYRDVMLENYSHLVSVGYLVAKPDVIFRLGPGEESWMADGGTPVRTCAEVWQVDEQIDHYKESQDKLPWQAAFIGKETLKDESGQESRTCRKSIYLSTEFDSVRQRLPKYYSWEKAFKTSFKLSWSKWKLCKKER

Target ORF information:

RefSeq Version	NM_017776.2
Organism	Homo sapiens(human)
Definition	Homo sapiens KRAB box domain containing 4 (KRBOX4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017776.2

ORF Insert Sequence:

ATGGCCATGT CCCAGGAATC ATTGACCTTC AAGGACGTGT TTGTGGACTT CACCCTGGAG 
GAGTGGCAGC AACTGGACTC TGCCCAGAAG AACCTCTACA GGGATGTCAT GCTTGAGAAC 
TACAGCCACC TGGTGTCCGT GGGGTATCTA GTTGCGAAGC CAGATGTGAT CTTCAGGTTG 
GGACCAGGTG AAGAGTCCTG GATGGCAGAT GGGGGGACCC CGGTACGGAC CTGTGCAGAA 
GTCTGGCAAG TTGATGAGCA GATAGATCAC TACAAGGAAA GCCAAGACAA ACTTCCTTGG 
CAAGCTGCAT TCATAGGCAA GGAAACACTG AAGGATGAAA GCGGTCAAGA ATCCAGAACA 
TGTAGAAAAA GCATTTATCT GAGCACAGAA TTTGATTCTG TAAGGCAAAG ACTCCCTAAA 
TATTATTCGT GGGAAAAGGC ATTCAAAACA TCATTTAAAC TTTCTTGGTC AAAATGGAAG 
CTATGTAAGA AAGAAAGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ZNF674: a new kruppel-associated box-containing zinc-finger gene involved in nonsyndromic X-linked mental retardation.
American journal of human genetics78(2)265-78(2006 Feb)
Lugtenberg D,Yntema HG,Banning MJ,Oudakker AR,Firth HV,Willatt L,Raynaud M,Kleefstra T,Fryns JP,Ropers HH,Chelly J,Moraine C,Gecz J,van Reeuwijk J,Nabuurs SB,de Vries BB,Hamel BC,de Brouwer AP,van Bokhoven H

The DNA sequence of the human X chromosome.
Nature434(7031)325-37(2005 Mar)
Ross MT,Grafham DV,Coffey AJ,Scherer S,McLay K,Muzny D,Platzer M,Howell GR,Burrows C,Bird CP,Frankish A,Lovell FL,Howe KL,Ashurst JL,Fulton RS,Sudbrak R,Wen G,Jones MC,Hurles ME,Andrews TD,Scott CE,Searle S,Ramser J,Whittaker A,Deadman R,Carter NP,Hunt SE,Chen R,Cree A,Gunaratne P,Havlak P,Hodgson A,Metzker ML,Richards S,Scott G,Steffen D,Sodergren E,Wheeler DA,Worley KC,Ainscough R,Ambrose KD,Ansari-Lari MA,Aradhya S,Ashwell RI,Babbage AK,Bagguley CL,Ballabio A,Banerjee R,Barker GE,Barlow KF,Barrett IP,Bates KN,Beare DM,Beasley H,Beasley O,Beck A,Bethel G,Blechschmidt K,Brady N,Bray-Allen S,Bridgeman AM,Brown AJ,Brown MJ,Bonnin D,Bruford EA,Buhay C,Burch P,Burford D,Burgess J,Burrill W,Burton J,Bye JM,Carder C,Carrel L,Chako J,Chapman JC,Chavez D,Chen E,Chen G,Chen Y,Chen Z,Chinault C,Ciccodicola A,Clark SY,Clarke G,Clee CM,Clegg S,Clerc-Blankenburg K,Clifford K,Cobley V,Cole CG,Conquer JS,Corby N,Connor RE,David R,Davies J,Davis C,Davis J,Delgado O,Deshazo D,Dhami P,Ding Y,Dinh H,Dodsworth S,Draper H,Dugan-Rocha S,Dunham A,Dunn M,Durbin KJ,Dutta I,Eades T,Ellwood M,Emery-Cohen A,Errington H,Evans KL,Faulkner L,Francis F,Frankland J,Fraser AE,Galgoczy P,Gilbert J,Gill R,Gl?ckner G,Gregory SG,Gribble S,Griffiths C,Grocock R,Gu Y,Gwilliam R,Hamilton C,Hart EA,Hawes A,Heath PD,Heitmann K,Hennig S,Hernandez J,Hinzmann B,Ho S,Hoffs M,Howden PJ,Huckle EJ,Hume J,Hunt PJ,Hunt AR,Isherwood J,Jacob L,Johnson D,Jones S,de Jong PJ,Joseph SS,Keenan S,Kelly S,Kershaw JK,Khan Z,Kioschis P,Klages S,Knights AJ,Kosiura A,Kovar-Smith C,Laird GK,Langford C,Lawlor S,Leversha M,Lewis L,Liu W,Lloyd C,Lloyd DM,Loulseged H,Loveland JE,Lovell JD,Lozado R,Lu J,Lyne R,Ma J,Maheshwari M,Matthews LH,McDowall J,McLaren S,McMurray A,Meidl P,Meitinger T,Milne S,Miner G,Mistry SL,Morgan M,Morris S,M?ller I,Mullikin JC,Nguyen N,Nordsiek G,Nyakatura G,O'Dell CN,Okwuonu G,Palmer S,Pandian R,Parker D,Parrish J,Pasternak S,Patel D,Pearce AV,Pearson DM,Pelan SE,Perez L,Porter KM,Ramsey Y,Reichwald K,Rhodes S,Ridler KA,Schlessinger D,Schueler MG,Sehra HK,Shaw-Smith C,Shen H,Sheridan EM,Shownkeen R,Skuce CD,Smith ML,Sotheran EC,Steingruber HE,Steward CA,Storey R,Swann RM,Swarbreck D,Tabor PE,Taudien S,Taylor T,Teague B,Thomas K,Thorpe A,Timms K,Tracey A,Trevanion S,Tromans AC,d'Urso M,Verduzco D,Villasana D,Waldron L,Wall M,Wang Q,Warren J,Warry GL,Wei X,West A,Whitehead SL,Whiteley MN,Wilkinson JE,Willey DL,Williams G,Williams L,Williamson A,Williamson H,Wilming L,Woodmansey RL,Wray PW,Yen J,Zhang J,Zhou J,Zoghbi H,Zorilla S,Buck D,Reinhardt R,Poustka A,Rosenthal A,Lehrach H,Meindl A,Minx PJ,Hillier LW,Willard HF,Wilson RK,Waterston RH,Rice CM,Vaudin M,Coulson A,Nelson DL,Weinstock G,Sulston JE,Durbin R,Hubbard T,Gibbs RA,Beck S,Rogers J,Bentley DR

An integrated, functionally annotated gene map of the DXS8026-ELK1 interval on human Xp11.3-Xp11.23: potential hotspot for neurogenetic disorders.
Genomics79(4)560-72(2002 Apr)
Thiselton DL,McDowall J,Brandau O,Ramser J,d'Esposito F,Bhattacharya SS,Ross MT,Hardcastle AJ,Meindl A

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KRBOX4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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