PARL cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PARL
Entrez Gene ID	55486
Full Name	presenilin associated rhomboid like
Synonyms	PRO2207,PSARL,PSARL1,PSENIP2,RHBDS1
General protein information	Preferred Names presenilin associated rhomboid like Names presenilins-associated rhomboid-like protein, mitochondrial mitochondrial intramembrane-cleaving protease PARL rhomboid 7 homolog 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q27.1
Summary	This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease. [provided by RefSeq, May 2016].
Disorder MIM:	607858

mRNA and Protein(s)

mRNA	Protein	Name
NM_001324438.1	NP_001311367.1	presenilins-associated rhomboid-like protein, mitochondrial isoform 5 precursor
XM_017006800.2	XP_016862289.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X2
XM_024453629.1	XP_024309397.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X5
NM_001037639.3	NP_001032728.1	presenilins-associated rhomboid-like protein, mitochondrial isoform 2
NM_001324437.2	NP_001311366.1	presenilins-associated rhomboid-like protein, mitochondrial isoform 4
XM_024453632.1	XP_024309400.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X6
NM_018622.5	NP_061092.3	presenilins-associated rhomboid-like protein, mitochondrial isoform 1 preproprotein
NM_018622.6	NP_061092.3	presenilins-associated rhomboid-like protein, mitochondrial isoform 1 precursor
NM_001037639.2	NP_001032728.1	presenilins-associated rhomboid-like protein, mitochondrial isoform 2
XM_017006801.1	XP_016862290.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X3
XM_017006802.1	XP_016862291.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X4
XM_024453628.1	XP_024309396.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X5
XM_024453631.1	XP_024309399.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X5
XM_024453633.1	XP_024309401.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X6
XM_017006803.1	XP_016862292.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X7
NM_001324436.2	NP_001311365.1	presenilins-associated rhomboid-like protein, mitochondrial isoform 3
NM_001324436.1	NP_001311365.1	presenilins-associated rhomboid-like protein, mitochondrial isoform 3
XM_005247582.5	XP_005247639.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X1
XM_024453630.1	XP_024309398.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X5
NM_001324437.1	NP_001311366.1	presenilins-associated rhomboid-like protein, mitochondrial isoform 4
XM_005247582.4	XP_005247639.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X1
XM_017006800.1	XP_016862289.1	presenilins-associated rhomboid-like protein, mitochondrial isoform X2
NM_018622.7	NP_061092.3	presenilins-associated rhomboid-like protein, mitochondrial isoform 1 precursor
NM_001324438.2	NP_001311367.1	presenilins-associated rhomboid-like protein, mitochondrial isoform 5 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Parl	NP_001030326.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002626	XP_312303.4
Schizosaccharomyces pombe (fission yeast)	SPBC13E7.11	NP_596266.2
Homo sapiens (human)	PARL	NP_061092.3
Danio rerio (zebrafish)	LOC792889	XP_001331983.4
Xenopus tropicalis (tropical clawed frog)	parl	NP_001165755.1
Mus musculus (house mouse)	Parl	NP_001005767.1
Drosophila melanogaster (fruit fly)	rho-7	NP_523704.1
Pan troglodytes (chimpanzee)	PARL	XP_001135897.1
Canis lupus familiaris (dog)	PARL	XP_545224.2
	PARL	XP_001105563.1
Bos taurus (cattle)	PARL	NP_001015596.1
Gallus gallus (chicken)	PARL	XP_422588.4

Gene Ontology
Bibliography

Related articles in PubMed

PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria.
Saita S, Tatsuta T, Lampe PA, K?nig T, Ohba Y, Langer T
The EMBO journal(2018 Jan)

Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese.
Tang FY, Ma L, Tam POS, Pang CP, Tham CCY, Chen LJ
Investigative ophthalmology & visual science58(10)4384?4389(2017 08)

Role of PARL-PINK1-Parkin pathway in adipocyte differentiation.
Shiau MY, Lee PS, Huang YJ, Yang CP, Hsiao CW, Chang KY, Chen HW, Chang YH
Metabolism: clinical and experimental721-17(2017 Jul)

PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
Saita S, Nolte H, Fiedler KU, Kashkar H, Venne AS, Zahedi RP, Kr?ger M, Langer T
Nature cell biology19(4)318-328(2017 Apr)

The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism.
Shi G, McQuibban GA
Cell reports18(6)1458-1472(2017 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings enrich the allelic spectrum of ABCC5 in PACG. We identified no tagging SNP responsible for the association of the whole region.
Title: Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese.

Adipogenic process can be dissected into 3 stages according to the participation of PARL-PINK1-Parkin system. Findings reveal the sequential adipogenic events directed by PARL-PINK1-Parkin system, add more evidence supporting the convergence of pathogenesis leading to neurodegenerative and metabolic disease
Title: Role of PARL-PINK1-Parkin pathway in adipocyte differentiation.

These results reveal a pro-apoptotic function of PARL and identify PARL-mediated Smac processing and cytochrome c release facilitated by OPA1-dependent cristae remodelling as two independent pro-apoptotic pathways in mitochondria.
Title: PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.

PDK2/PARL senses defects in mitochondrial bioenergetics.
Title: The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism.

Its mutations are a rare cause of PD and genetic variants are neither strong nor common risk factors in Parkinson disease.
Title: Mutation analyses and association studies to assess the role of the presenilin-associated rhomboid-like gene in Parkinson's disease.

The following PARL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PARL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13199	NM_018622.7 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu13107	NM_001037639.3 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu38018	NM_001324436.2 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu38016	XM_005247582.5 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu38021	XM_024453632.1 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu38021	XM_024453633.1 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu101768	NM_001324438.2 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu101782	NM_001324437.2 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu105396	XM_024453630.1 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu105396	XM_024453629.1 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu105396	XM_024453628.1 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu105396	XM_024453631.1 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu94353	XM_017006800.2 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu94354	XM_017006801.1 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu94355	XM_017006802.1 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu94356	XM_017006803.1 Latest version!	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X11, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu13199	NM_018622.5	Homo sapiens presenilin associated, rhomboid-like (PARL), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu13107	NM_001037639.2	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu38018	NM_001324436.1	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu101782	NM_001324437.1	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu38016	XM_005247582.4	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu94353	XM_017006800.1	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu13199	NM_018622.6	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu101768	NM_001324438.1	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PARL ( NM_018622.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_061092.3 Homo sapiens presenilin associated, rhomboid-like (PARL), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13199
Clone ID Related Accession (Same CDS sequence)	NM_018622.5 , NM_018622.6 , NM_018622.7
Accession Version	NM_018622.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform 1 preproprotein
Comment

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCATC TGGTGCCATC 
ATGACAGTCC TCGCAGCTGT CTGCACTAAG ATCCCAGAAG GGAGGCTTGC CATTATTTTC 
CTTCCGATGT TCACGTTCAC AGCAGGGAAT GCCCTGAAAG CCATTATCGC CATGGATACA 
GCAGGAATGA TCCTGGGATG GAAATTTTTT GATCATGCGG CACATCTTGG GGGAGCTCTT 
TTTGGAATAT GGTATGTTAC TTACGGTCAT GAACTGATTT GGAAGAACAG GGAGCCGCTA 
GTGAAAATCT GGCATGAAAT AAGGACTAAT GGCCCCAAAA AAGGAGGTGG CTCTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061092.3
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Target ORF information:

RefSeq Version	NM_018622.5
Organism	Homo sapiens(Human)
Definition	Homo sapiens presenilin associated, rhomboid-like (PARL), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018622.5

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCATC TGGTGCCATC 
ATGACAGTCC TCGCAGCTGT CTGCACTAAG ATCCCAGAAG GGAGGCTTGC CATTATTTTC 
CTTCCGATGT TCACGTTCAC AGCAGGGAAT GCCCTGAAAG CCATTATCGC CATGGATACA 
GCAGGAATGA TCCTGGGATG GAAATTTTTT GATCATGCGG CACATCTTGG GGGAGCTCTT 
TTTGGAATAT GGTATGTTAC TTACGGTCAT GAACTGATTT GGAAGAACAG GGAGCCGCTA 
GTGAAAATCT GGCATGAAAT AAGGACTAAT GGCCCCAAAA AAGGAGGTGG CTCTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( NM_018622.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_061092.3 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13199
Clone ID Related Accession (Same CDS sequence)	NM_018622.5 , NM_018622.6 , NM_018622.7
Accession Version	NM_018622.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG714761.1, CB122278.1, BC014058.2 and CA417847.1. This sequence is a reference standard in the RefSeqGene project. On May 5, 2016 this sequence version replaced NM_018622.5. Transcript Variant: This variant (1) encodes the longest isoform (1), which is localized to the mitochondria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK024765.1, SRR1163658.88748.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCATC TGGTGCCATC 
ATGACAGTCC TCGCAGCTGT CTGCACTAAG ATCCCAGAAG GGAGGCTTGC CATTATTTTC 
CTTCCGATGT TCACGTTCAC AGCAGGGAAT GCCCTGAAAG CCATTATCGC CATGGATACA 
GCAGGAATGA TCCTGGGATG GAAATTTTTT GATCATGCGG CACATCTTGG GGGAGCTCTT 
TTTGGAATAT GGTATGTTAC TTACGGTCAT GAACTGATTT GGAAGAACAG GGAGCCGCTA 
GTGAAAATCT GGCATGAAAT AAGGACTAAT GGCCCCAAAA AAGGAGGTGG CTCTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061092.3
CDS	63..1202
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Target ORF information:

RefSeq Version	NM_018622.6
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018622.6

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCATC TGGTGCCATC 
ATGACAGTCC TCGCAGCTGT CTGCACTAAG ATCCCAGAAG GGAGGCTTGC CATTATTTTC 
CTTCCGATGT TCACGTTCAC AGCAGGGAAT GCCCTGAAAG CCATTATCGC CATGGATACA 
GCAGGAATGA TCCTGGGATG GAAATTTTTT GATCATGCGG CACATCTTGG GGGAGCTCTT 
TTTGGAATAT GGTATGTTAC TTACGGTCAT GAACTGATTT GGAAGAACAG GGAGCCGCTA 
GTGAAAATCT GGCATGAAAT AAGGACTAAT GGCCCCAAAA AAGGAGGTGG CTCTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( NM_018622.7 ) cDNA ORF clone, Homo sapiens(human) -> NP_061092.3 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13199
Clone ID Related Accession (Same CDS sequence)	NM_018622.5 , NM_018622.6 , NM_018622.7
Accession Version	NM_018622.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1140bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CB122278.1, BC014058.2, CA417847.1 and AC131160.6. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_018622.6. Transcript Variant: This variant (1) encodes the longest isoform (1), which is localized to the mitochondria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK024765.1, SRR1660805.377064.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCATC TGGTGCCATC 
ATGACAGTCC TCGCAGCTGT CTGCACTAAG ATCCCAGAAG GGAGGCTTGC CATTATTTTC 
CTTCCGATGT TCACGTTCAC AGCAGGGAAT GCCCTGAAAG CCATTATCGC CATGGATACA 
GCAGGAATGA TCCTGGGATG GAAATTTTTT GATCATGCGG CACATCTTGG GGGAGCTCTT 
TTTGGAATAT GGTATGTTAC TTACGGTCAT GAACTGATTT GGAAGAACAG GGAGCCGCTA 
GTGAAAATCT GGCATGAAAT AAGGACTAAT GGCCCCAAAA AAGGAGGTGG CTCTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061092.3
CDS	35..1174
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Target ORF information:

RefSeq Version	NM_018622.7
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018622.7

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCATC TGGTGCCATC 
ATGACAGTCC TCGCAGCTGT CTGCACTAAG ATCCCAGAAG GGAGGCTTGC CATTATTTTC 
CTTCCGATGT TCACGTTCAC AGCAGGGAAT GCCCTGAAAG CCATTATCGC CATGGATACA 
GCAGGAATGA TCCTGGGATG GAAATTTTTT GATCATGCGG CACATCTTGG GGGAGCTCTT 
TTTGGAATAT GGTATGTTAC TTACGGTCAT GAACTGATTT GGAAGAACAG GGAGCCGCTA 
GTGAAAATCT GGCATGAAAT AAGGACTAAT GGCCCCAAAA AAGGAGGTGG CTCTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( NM_001037639.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001032728.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13107
Clone ID Related Accession (Same CDS sequence)	NM_001037639.3 , NM_001037639.2
Accession Version	NM_001037639.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC003653.1, BC014058.2, CA417847.1 and AC131160.6. On Jun 2, 2019 this sequence version replaced NM_001037639.2. Transcript Variant: This variant (2) lacks an exon in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. The encoded isoform (2) may be localized to the mitochondria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC003653.1, SRR1163657.265196.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCATC TGGTGCCATC ATGACAGTCC TCGCAGCTGT CTGCACTAAG 
ATCCCAGAAG GGAGGCTTGC CATTATTTTC CTTCCGATGT TCACGTTCAC AGCAGGGAAT 
GCCCTGAAAG CCATTATCGC CATGGATACA GCAGGAATGA TCCTGGGATG GAAATTTTTT 
GATCATGCGG CACATCTTGG GGGAGCTCTT TTTGGAATAT GGTATGTTAC TTACGGTCAT 
GAACTGATTT GGAAGAACAG GGAGCCGCTA GTGAAAATCT GGCATGAAAT AAGGACTAAT 
GGCCCCAAAA AAGGAGGTGG CTCTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032728.1
CDS	35..1024
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Target ORF information:

RefSeq Version	NM_001037639.3
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037639.3

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCATC TGGTGCCATC ATGACAGTCC TCGCAGCTGT CTGCACTAAG 
ATCCCAGAAG GGAGGCTTGC CATTATTTTC CTTCCGATGT TCACGTTCAC AGCAGGGAAT 
GCCCTGAAAG CCATTATCGC CATGGATACA GCAGGAATGA TCCTGGGATG GAAATTTTTT 
GATCATGCGG CACATCTTGG GGGAGCTCTT TTTGGAATAT GGTATGTTAC TTACGGTCAT 
GAACTGATTT GGAAGAACAG GGAGCCGCTA GTGAAAATCT GGCATGAAAT AAGGACTAAT 
GGCCCCAAAA AAGGAGGTGG CTCTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( NM_001037639.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001032728.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13107
Clone ID Related Accession (Same CDS sequence)	NM_001037639.3 , NM_001037639.2
Accession Version	NM_001037639.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG714761.1, CB122278.1, BC003653.1, BC014058.2 and CA417847.1. On May 5, 2016 this sequence version replaced NM_001037639.1. Transcript Variant: This variant (2) lacks an exon in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. The encoded isoform (2) may be localized to the mitochondria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC003653.1, SRR1163655.405342.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCATC TGGTGCCATC ATGACAGTCC TCGCAGCTGT CTGCACTAAG 
ATCCCAGAAG GGAGGCTTGC CATTATTTTC CTTCCGATGT TCACGTTCAC AGCAGGGAAT 
GCCCTGAAAG CCATTATCGC CATGGATACA GCAGGAATGA TCCTGGGATG GAAATTTTTT 
GATCATGCGG CACATCTTGG GGGAGCTCTT TTTGGAATAT GGTATGTTAC TTACGGTCAT 
GAACTGATTT GGAAGAACAG GGAGCCGCTA GTGAAAATCT GGCATGAAAT AAGGACTAAT 
GGCCCCAAAA AAGGAGGTGG CTCTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001032728.1
CDS	63..1052
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Target ORF information:

RefSeq Version	NM_001037639.2
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001037639.2

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCATC TGGTGCCATC ATGACAGTCC TCGCAGCTGT CTGCACTAAG 
ATCCCAGAAG GGAGGCTTGC CATTATTTTC CTTCCGATGT TCACGTTCAC AGCAGGGAAT 
GCCCTGAAAG CCATTATCGC CATGGATACA GCAGGAATGA TCCTGGGATG GAAATTTTTT 
GATCATGCGG CACATCTTGG GGGAGCTCTT TTTGGAATAT GGTATGTTAC TTACGGTCAT 
GAACTGATTT GGAAGAACAG GGAGCCGCTA GTGAAAATCT GGCATGAAAT AAGGACTAAT 
GGCCCCAAAA AAGGAGGTGG CTCTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( NM_001324436.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311365.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu38018
Clone ID Related Accession (Same CDS sequence)	NM_001324436.2 , NM_001324436.1
Accession Version	NM_001324436.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1038bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC068644.15, AC131160.6 and CA417847.1. On Jun 2, 2019 this sequence version replaced NM_001324436.1. Transcript Variant: This variant (3) encodes isoform 3, which may be localized to the mitochondria. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.146890.1, SRR1163655.448089.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAGC CCTGAAAGCC 
ATTATCGCCA TGGATACAGC AGGAATGATC CTGGGATGGA AATTTTTTGA TCATGCGGCA 
CATCTTGGGG GAGCTCTTTT TGGAATATGG TATGTTACTT ACGGTCATGA ACTGATTTGG 
AAGAACAGGG AGCCGCTAGT GAAAATCTGG CATGAAATAA GGACTAATGG CCCCAAAAAA 
GGAGGTGGCT CTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311365.1
CDS	35..1072
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGAALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Target ORF information:

RefSeq Version	NM_001324436.2
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324436.2

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAGC CCTGAAAGCC 
ATTATCGCCA TGGATACAGC AGGAATGATC CTGGGATGGA AATTTTTTGA TCATGCGGCA 
CATCTTGGGG GAGCTCTTTT TGGAATATGG TATGTTACTT ACGGTCATGA ACTGATTTGG 
AAGAACAGGG AGCCGCTAGT GAAAATCTGG CATGAAATAA GGACTAATGG CCCCAAAAAA 
GGAGGTGGCT CTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( NM_001324436.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311365.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu38018
Clone ID Related Accession (Same CDS sequence)	NM_001324436.2 , NM_001324436.1
Accession Version	NM_001324436.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1038bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG714761.1, AC068644.15, AC131160.6 and CA417847.1. On May 5, 2016 this sequence version replaced XM_005247584.3. Transcript Variant: This variant (3) encodes isoform 3, which may be localized to the mitochondria. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.146890.1, SRR1163655.448089.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAGC CCTGAAAGCC 
ATTATCGCCA TGGATACAGC AGGAATGATC CTGGGATGGA AATTTTTTGA TCATGCGGCA 
CATCTTGGGG GAGCTCTTTT TGGAATATGG TATGTTACTT ACGGTCATGA ACTGATTTGG 
AAGAACAGGG AGCCGCTAGT GAAAATCTGG CATGAAATAA GGACTAATGG CCCCAAAAAA 
GGAGGTGGCT CTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311365.1
CDS	63..1100
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGAALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Target ORF information:

RefSeq Version	NM_001324436.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324436.1

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAGC CCTGAAAGCC 
ATTATCGCCA TGGATACAGC AGGAATGATC CTGGGATGGA AATTTTTTGA TCATGCGGCA 
CATCTTGGGG GAGCTCTTTT TGGAATATGG TATGTTACTT ACGGTCATGA ACTGATTTGG 
AAGAACAGGG AGCCGCTAGT GAAAATCTGG CATGAAATAA GGACTAATGG CCCCAAAAAA 
GGAGGTGGCT CTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_005247582.5 ) cDNA ORF clone, Homo sapiens(human) -> XP_005247639.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu38016
Clone ID Related Accession (Same CDS sequence)	XM_005247582.5 , XM_005247582.4
Accession Version	XM_005247582.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1185bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005247582.4. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCATC TGGTGCCATC 
ATGACAGTCC TCGCAGCTGT CTGCACTAAG ATCCCAGAAG GGAGGCTTGC CATTATTTTC 
CTTCCGATGT TCACGTTCAC AGCAGGGAAT GCCCTGAAAG CCATTATCGC CATGGATACA 
GCAGGAATGA TCCTGGGATG GAAATTTTTT GATCATGCGG CACATCTTGG GGGAGCTCTT 
TTTGGAATGA TCTCCCTCTA CACCTGGCGC CTCGCCTGCT GCCTGCTGGG ACATGGCCTG 
GCCTGCTCAG CTGACCTGCT GCCACTTCTA GGCAGCCGTC ATGTCACTTT GCTACAACTT 
CAAGCTAAGA CAGGCAATGT TTTGGGAGAT GAATCTGTTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005247639.1
CDS	56..1240
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF

Target ORF information:

RefSeq Version	XM_005247582.5
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005247582.5

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCATC TGGTGCCATC 
ATGACAGTCC TCGCAGCTGT CTGCACTAAG ATCCCAGAAG GGAGGCTTGC CATTATTTTC 
CTTCCGATGT TCACGTTCAC AGCAGGGAAT GCCCTGAAAG CCATTATCGC CATGGATACA 
GCAGGAATGA TCCTGGGATG GAAATTTTTT GATCATGCGG CACATCTTGG GGGAGCTCTT 
TTTGGAATGA TCTCCCTCTA CACCTGGCGC CTCGCCTGCT GCCTGCTGGG ACATGGCCTG 
GCCTGCTCAG CTGACCTGCT GCCACTTCTA GGCAGCCGTC ATGTCACTTT GCTACAACTT 
CAAGCTAAGA CAGGCAATGT TTTGGGAGAT GAATCTGTTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_005247582.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005247639.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu38016
Clone ID Related Accession (Same CDS sequence)	XM_005247582.5 , XM_005247582.4
Accession Version	XM_005247582.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1185bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005247582.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCATC TGGTGCCATC 
ATGACAGTCC TCGCAGCTGT CTGCACTAAG ATCCCAGAAG GGAGGCTTGC CATTATTTTC 
CTTCCGATGT TCACGTTCAC AGCAGGGAAT GCCCTGAAAG CCATTATCGC CATGGATACA 
GCAGGAATGA TCCTGGGATG GAAATTTTTT GATCATGCGG CACATCTTGG GGGAGCTCTT 
TTTGGAATGA TCTCCCTCTA CACCTGGCGC CTCGCCTGCT GCCTGCTGGG ACATGGCCTG 
GCCTGCTCAG CTGACCTGCT GCCACTTCTA GGCAGCCGTC ATGTCACTTT GCTACAACTT 
CAAGCTAAGA CAGGCAATGT TTTGGGAGAT GAATCTGTTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005247639.1
CDS	58..1242
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF

Target ORF information:

RefSeq Version	XM_005247582.4
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005247582.4

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCATC TGGTGCCATC 
ATGACAGTCC TCGCAGCTGT CTGCACTAAG ATCCCAGAAG GGAGGCTTGC CATTATTTTC 
CTTCCGATGT TCACGTTCAC AGCAGGGAAT GCCCTGAAAG CCATTATCGC CATGGATACA 
GCAGGAATGA TCCTGGGATG GAAATTTTTT GATCATGCGG CACATCTTGG GGGAGCTCTT 
TTTGGAATGA TCTCCCTCTA CACCTGGCGC CTCGCCTGCT GCCTGCTGGG ACATGGCCTG 
GCCTGCTCAG CTGACCTGCT GCCACTTCTA GGCAGCCGTC ATGTCACTTT GCTACAACTT 
CAAGCTAAGA CAGGCAATGT TTTGGGAGAT GAATCTGTTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_024453632.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024309400.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X9, mRNA.

Price & Availability↑

CloneID	OHu38021
Clone ID Related Accession (Same CDS sequence)	XM_024453632.1 , XM_024453633.1
Accession Version	XM_024453632.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X6
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATATGGT ATGTTACTTA CGGTCATGAA 
CTGATTTGGA AGAACAGGGA GCCGCTAGTG AAAATCTGGC ATGAAATAAG GACTAATGGC 
CCCAAAAAAG GAGGTGGCTC TAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024309400.1
CDS	783..1349
Translation	MIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Target ORF information:

RefSeq Version	XM_024453632.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024453632.1

ORF Insert Sequence:

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATATGGT ATGTTACTTA CGGTCATGAA 
CTGATTTGGA AGAACAGGGA GCCGCTAGTG AAAATCTGGC ATGAAATAAG GACTAATGGC 
CCCAAAAAAG GAGGTGGCTC TAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_024453633.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024309401.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X10, mRNA.

Price & Availability↑

CloneID	OHu38021
Clone ID Related Accession (Same CDS sequence)	XM_024453632.1 , XM_024453633.1
Accession Version	XM_024453633.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 567bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X6
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATATGGT ATGTTACTTA CGGTCATGAA 
CTGATTTGGA AGAACAGGGA GCCGCTAGTG AAAATCTGGC ATGAAATAAG GACTAATGGC 
CCCAAAAAAG GAGGTGGCTC TAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024309401.1
CDS	710..1276
Translation	MIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Target ORF information:

RefSeq Version	XM_024453633.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024453633.1

ORF Insert Sequence:

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATATGGT ATGTTACTTA CGGTCATGAA 
CTGATTTGGA AGAACAGGGA GCCGCTAGTG AAAATCTGGC ATGAAATAAG GACTAATGGC 
CCCAAAAAAG GAGGTGGCTC TAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( NM_001324438.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311367.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu101768
Clone ID Related Accession (Same CDS sequence)	NM_001324438.1 , NM_001324438.2
Accession Version	NM_001324438.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 852bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG714761.1, AC068644.15, AC131160.6 and CA417847.1. Transcript Variant: This variant (5) encodes isoform 5, which is localized to the mitochondria. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.273062.1, SRR1163655.428469.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAAT GGTATGTTAC 
TTACGGTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311367.1
CDS	63..914
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGAMVCYLRS

Target ORF information:

RefSeq Version	NM_001324438.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324438.1

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAAT GGTATGTTAC 
TTACGGTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( NM_001324438.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311367.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu101768
Clone ID Related Accession (Same CDS sequence)	NM_001324438.1 , NM_001324438.2
Accession Version	NM_001324438.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 852bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform 5 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC068644.15, AC131160.6 and CA417847.1. On Jun 3, 2019 this sequence version replaced NM_001324438.1. Transcript Variant: This variant (5) encodes isoform 5, which is localized to the mitochondria. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.445399.1, SRR1163657.273062.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAAT GGTATGTTAC 
TTACGGTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311367.1
CDS	35..886
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGAMVCYLRS

Target ORF information:

RefSeq Version	NM_001324438.2
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324438.2

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAAT GGTATGTTAC 
TTACGGTCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( NM_001324437.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311366.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu101782
Clone ID Related Accession (Same CDS sequence)	NM_001324437.2 , NM_001324437.1
Accession Version	NM_001324437.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC068644.15, AC131160.6 and CA417847.1. On Jun 2, 2019 this sequence version replaced NM_001324437.1. Transcript Variant: This variant (4) encodes isoform 4, which may be localized to the mitochondria. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.257893.1, SRR1163658.134833.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCAGC CCTGAAAGCC ATTATCGCCA TGGATACAGC AGGAATGATC 
CTGGGATGGA AATTTTTTGA TCATGCGGCA CATCTTGGGG GAGCTCTTTT TGGAATATGG 
TATGTTACTT ACGGTCATGA ACTGATTTGG AAGAACAGGG AGCCGCTAGT GAAAATCTGG 
CATGAAATAA GGACTAATGG CCCCAAAAAA GGAGGTGGCT CTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311366.1
CDS	35..922
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGAALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Target ORF information:

RefSeq Version	NM_001324437.2
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324437.2

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCAGC CCTGAAAGCC ATTATCGCCA TGGATACAGC AGGAATGATC 
CTGGGATGGA AATTTTTTGA TCATGCGGCA CATCTTGGGG GAGCTCTTTT TGGAATATGG 
TATGTTACTT ACGGTCATGA ACTGATTTGG AAGAACAGGG AGCCGCTAGT GAAAATCTGG 
CATGAAATAA GGACTAATGG CCCCAAAAAA GGAGGTGGCT CTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( NM_001324437.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311366.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu101782
Clone ID Related Accession (Same CDS sequence)	NM_001324437.2 , NM_001324437.1
Accession Version	NM_001324437.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG714761.1, AC068644.15, AC131160.6 and CA417847.1. Transcript Variant: This variant (4) encodes isoform 4, which may be localized to the mitochondria. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.257893.1, SRR1163658.134833.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCAGC CCTGAAAGCC ATTATCGCCA TGGATACAGC AGGAATGATC 
CTGGGATGGA AATTTTTTGA TCATGCGGCA CATCTTGGGG GAGCTCTTTT TGGAATATGG 
TATGTTACTT ACGGTCATGA ACTGATTTGG AAGAACAGGG AGCCGCTAGT GAAAATCTGG 
CATGAAATAA GGACTAATGG CCCCAAAAAA GGAGGTGGCT CTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311366.1
CDS	63..950
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGAALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK

Target ORF information:

RefSeq Version	NM_001324437.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324437.1

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCAGC CCTGAAAGCC ATTATCGCCA TGGATACAGC AGGAATGATC 
CTGGGATGGA AATTTTTTGA TCATGCGGCA CATCTTGGGG GAGCTCTTTT TGGAATATGG 
TATGTTACTT ACGGTCATGA ACTGATTTGG AAGAACAGGG AGCCGCTAGT GAAAATCTGG 
CATGAAATAA GGACTAATGG CCCCAAAAAA GGAGGTGGCT CTAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_024453629.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024309397.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu105396
Clone ID Related Accession (Same CDS sequence)	XM_024453629.1 , XM_024453628.1 , XM_024453631.1 , XM_024453630.1
Accession Version	XM_024453629.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATGATCT CCCTCTACAC CTGGCGCCTC 
GCCTGCTGCC TGCTGGGACA TGGCCTGGCC TGCTCAGCTG ACCTGCTGCC ACTTCTAGGC 
AGCCGTCATG TCACTTTGCT ACAACTTCAA GCTAAGACAG GCAATGTTTT GGGAGATGAA 
TCTGTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024309397.1
CDS	384..995
Translation	MIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF

Target ORF information:

RefSeq Version	XM_024453629.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024453629.1

ORF Insert Sequence:

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATGATCT CCCTCTACAC CTGGCGCCTC 
GCCTGCTGCC TGCTGGGACA TGGCCTGGCC TGCTCAGCTG ACCTGCTGCC ACTTCTAGGC 
AGCCGTCATG TCACTTTGCT ACAACTTCAA GCTAAGACAG GCAATGTTTT GGGAGATGAA 
TCTGTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_024453628.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024309396.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu105396
Clone ID Related Accession (Same CDS sequence)	XM_024453629.1 , XM_024453628.1 , XM_024453631.1 , XM_024453630.1
Accession Version	XM_024453628.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATGATCT CCCTCTACAC CTGGCGCCTC 
GCCTGCTGCC TGCTGGGACA TGGCCTGGCC TGCTCAGCTG ACCTGCTGCC ACTTCTAGGC 
AGCCGTCATG TCACTTTGCT ACAACTTCAA GCTAAGACAG GCAATGTTTT GGGAGATGAA 
TCTGTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024309396.1
CDS	816..1427
Translation	MIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF

Target ORF information:

RefSeq Version	XM_024453628.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024453628.1

ORF Insert Sequence:

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATGATCT CCCTCTACAC CTGGCGCCTC 
GCCTGCTGCC TGCTGGGACA TGGCCTGGCC TGCTCAGCTG ACCTGCTGCC ACTTCTAGGC 
AGCCGTCATG TCACTTTGCT ACAACTTCAA GCTAAGACAG GCAATGTTTT GGGAGATGAA 
TCTGTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_024453631.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024309399.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X8, mRNA.

Price & Availability↑

CloneID	OHu105396
Clone ID Related Accession (Same CDS sequence)	XM_024453629.1 , XM_024453628.1 , XM_024453631.1 , XM_024453630.1
Accession Version	XM_024453631.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATGATCT CCCTCTACAC CTGGCGCCTC 
GCCTGCTGCC TGCTGGGACA TGGCCTGGCC TGCTCAGCTG ACCTGCTGCC ACTTCTAGGC 
AGCCGTCATG TCACTTTGCT ACAACTTCAA GCTAAGACAG GCAATGTTTT GGGAGATGAA 
TCTGTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024309399.1
CDS	1008..1619
Translation	MIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF

Target ORF information:

RefSeq Version	XM_024453631.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024453631.1

ORF Insert Sequence:

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATGATCT CCCTCTACAC CTGGCGCCTC 
GCCTGCTGCC TGCTGGGACA TGGCCTGGCC TGCTCAGCTG ACCTGCTGCC ACTTCTAGGC 
AGCCGTCATG TCACTTTGCT ACAACTTCAA GCTAAGACAG GCAATGTTTT GGGAGATGAA 
TCTGTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_024453630.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024309398.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X7, mRNA.

Price & Availability↑

CloneID	OHu105396
Clone ID Related Accession (Same CDS sequence)	XM_024453629.1 , XM_024453628.1 , XM_024453631.1 , XM_024453630.1
Accession Version	XM_024453630.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATGATCT CCCTCTACAC CTGGCGCCTC 
GCCTGCTGCC TGCTGGGACA TGGCCTGGCC TGCTCAGCTG ACCTGCTGCC ACTTCTAGGC 
AGCCGTCATG TCACTTTGCT ACAACTTCAA GCTAAGACAG GCAATGTTTT GGGAGATGAA 
TCTGTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024309398.1
CDS	710..1321
Translation	MIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF

Target ORF information:

RefSeq Version	XM_024453630.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024453630.1

ORF Insert Sequence:

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAAGGTCC TTTGTTCTCC AATGTTGCTG 
TCAACATTCA GTCATTTCTC CTTATTTCAC ATGGCAGCAA ATATGTATGT TTTGTGGAGC 
TTCTCTTCCA GCATAGTGAA CATTCTGGGT CAAGAGCAGT TCATGGCAGT GTACCTATCT 
GCAGGTGTTA TTTCCAATTT TGTCAGTTAC GTGGGTAAAG TTGCCACAGG AAGATATGGA 
CCATCACTTG GTGCATCTGG TGCCATCATG ACAGTCCTCG CAGCTGTCTG CACTAAGATC 
CCAGAAGGGA GGCTTGCCAT TATTTTCCTT CCGATGTTCA CGTTCACAGC AGGGAATGCC 
CTGAAAGCCA TTATCGCCAT GGATACAGCA GGAATGATCC TGGGATGGAA ATTTTTTGAT 
CATGCGGCAC ATCTTGGGGG AGCTCTTTTT GGAATGATCT CCCTCTACAC CTGGCGCCTC 
GCCTGCTGCC TGCTGGGACA TGGCCTGGCC TGCTCAGCTG ACCTGCTGCC ACTTCTAGGC 
AGCCGTCATG TCACTTTGCT ACAACTTCAA GCTAAGACAG GCAATGTTTT GGGAGATGAA 
TCTGTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_017006800.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862289.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu94353
Clone ID Related Accession (Same CDS sequence)	XM_017006800.2 , XM_017006800.1
Accession Version	XM_017006800.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017006800.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAGC CCTGAAAGCC 
ATTATCGCCA TGGATACAGC AGGAATGATC CTGGGATGGA AATTTTTTGA TCATGCGGCA 
CATCTTGGGG GAGCTCTTTT TGGAATGATC TCCCTCTACA CCTGGCGCCT CGCCTGCTGC 
CTGCTGGGAC ATGGCCTGGC CTGCTCAGCT GACCTGCTGC CACTTCTAGG CAGCCGTCAT 
GTCACTTTGC TACAACTTCA AGCTAAGACA GGCAATGTTT TGGGAGATGA ATCTGTTTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862289.1
CDS	56..1138
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGAALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF

Target ORF information:

RefSeq Version	XM_017006800.2
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006800.2

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAGC CCTGAAAGCC 
ATTATCGCCA TGGATACAGC AGGAATGATC CTGGGATGGA AATTTTTTGA TCATGCGGCA 
CATCTTGGGG GAGCTCTTTT TGGAATGATC TCCCTCTACA CCTGGCGCCT CGCCTGCTGC 
CTGCTGGGAC ATGGCCTGGC CTGCTCAGCT GACCTGCTGC CACTTCTAGG CAGCCGTCAT 
GTCACTTTGC TACAACTTCA AGCTAAGACA GGCAATGTTT TGGGAGATGA ATCTGTTTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_017006800.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862289.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu94353
Clone ID Related Accession (Same CDS sequence)	XM_017006800.2 , XM_017006800.1
Accession Version	XM_017006800.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAGC CCTGAAAGCC 
ATTATCGCCA TGGATACAGC AGGAATGATC CTGGGATGGA AATTTTTTGA TCATGCGGCA 
CATCTTGGGG GAGCTCTTTT TGGAATGATC TCCCTCTACA CCTGGCGCCT CGCCTGCTGC 
CTGCTGGGAC ATGGCCTGGC CTGCTCAGCT GACCTGCTGC CACTTCTAGG CAGCCGTCAT 
GTCACTTTGC TACAACTTCA AGCTAAGACA GGCAATGTTT TGGGAGATGA ATCTGTTTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862289.1
CDS	58..1140
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGAALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF

Target ORF information:

RefSeq Version	XM_017006800.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006800.1

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAAGG TCCTTTGTTC TCCAATGTTG CTGTCAACAT TCAGTCATTT CTCCTTATTT 
CACATGGCAG CAAATATGTA TGTTTTGTGG AGCTTCTCTT CCAGCATAGT GAACATTCTG 
GGTCAAGAGC AGTTCATGGC AGTGTACCTA TCTGCAGGTG TTATTTCCAA TTTTGTCAGT 
TACGTGGGTA AAGTTGCCAC AGGAAGATAT GGACCATCAC TTGGTGCAGC CCTGAAAGCC 
ATTATCGCCA TGGATACAGC AGGAATGATC CTGGGATGGA AATTTTTTGA TCATGCGGCA 
CATCTTGGGG GAGCTCTTTT TGGAATGATC TCCCTCTACA CCTGGCGCCT CGCCTGCTGC 
CTGCTGGGAC ATGGCCTGGC CTGCTCAGCT GACCTGCTGC CACTTCTAGG CAGCCGTCAT 
GTCACTTTGC TACAACTTCA AGCTAAGACA GGCAATGTTT TGGGAGATGA ATCTGTTTTC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_017006801.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862290.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu94354
Clone ID Related Accession (Same CDS sequence)	XM_017006801.1
Accession Version	XM_017006801.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCATC TGGTGCCATC ATGACAGTCC TCGCAGCTGT CTGCACTAAG 
ATCCCAGAAG GGAGGCTTGC CATTATTTTC CTTCCGATGT TCACGTTCAC AGCAGGGAAT 
GCCCTGAAAG CCATTATCGC CATGGATACA GCAGGAATGA TCCTGGGATG GAAATTTTTT 
GATCATGCGG CACATCTTGG GGGAGCTCTT TTTGGAATGA TCTCCCTCTA CACCTGGCGC 
CTCGCCTGCT GCCTGCTGGG ACATGGCCTG GCCTGCTCAG CTGACCTGCT GCCACTTCTA 
GGCAGCCGTC ATGTCACTTT GCTACAACTT CAAGCTAAGA CAGGCAATGT TTTGGGAGAT 
GAATCTGTTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862290.1
CDS	56..1090
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF

Target ORF information:

RefSeq Version	XM_017006801.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006801.1

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCATC TGGTGCCATC ATGACAGTCC TCGCAGCTGT CTGCACTAAG 
ATCCCAGAAG GGAGGCTTGC CATTATTTTC CTTCCGATGT TCACGTTCAC AGCAGGGAAT 
GCCCTGAAAG CCATTATCGC CATGGATACA GCAGGAATGA TCCTGGGATG GAAATTTTTT 
GATCATGCGG CACATCTTGG GGGAGCTCTT TTTGGAATGA TCTCCCTCTA CACCTGGCGC 
CTCGCCTGCT GCCTGCTGGG ACATGGCCTG GCCTGCTCAG CTGACCTGCT GCCACTTCTA 
GGCAGCCGTC ATGTCACTTT GCTACAACTT CAAGCTAAGA CAGGCAATGT TTTGGGAGAT 
GAATCTGTTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_017006802.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862291.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu94355
Clone ID Related Accession (Same CDS sequence)	XM_017006802.1
Accession Version	XM_017006802.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 933bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCAGC CCTGAAAGCC ATTATCGCCA TGGATACAGC AGGAATGATC 
CTGGGATGGA AATTTTTTGA TCATGCGGCA CATCTTGGGG GAGCTCTTTT TGGAATGATC 
TCCCTCTACA CCTGGCGCCT CGCCTGCTGC CTGCTGGGAC ATGGCCTGGC CTGCTCAGCT 
GACCTGCTGC CACTTCTAGG CAGCCGTCAT GTCACTTTGC TACAACTTCA AGCTAAGACA 
GGCAATGTTT TGGGAGATGA ATCTGTTTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862291.1
CDS	56..988
Translation	MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGAALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF

Target ORF information:

RefSeq Version	XM_017006802.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006802.1

ORF Insert Sequence:

ATGGCGTGGC GAGGCTGGGC GCAGAGAGGC TGGGGCTGCG GCCAGGCGTG GGGTGCGTCG 
GTGGGCGGCC GCAGCTGCGA GGAGCTCACT GCGGTCCTAA CCCCGCCGCA GCTCCTCGGA 
CGCAGGTTTA ACTTCTTTAT TCAACAAAAA TGCGGATTCA GAAAAGCACC CAGGAAGGTT 
GAACCTCGAA GATCAGACCC AGGGACAAGT GGTGAAGCAT ACAAGAGAAG TGCTTTGATT 
CCTCCTGTGG AAGAAACAGT CTTTTATCCT TCTCCCTATC CTATAAGGAG TCTCATAAAA 
CCTTTATTTT TTACTGTTGG GTTTACAGGC TGTGCATTTG GATCAGCTGC TATTTGGCAA 
TATGAATCAC TGAAATCCAG GGTCCAGAGT TATTTTGATG GTATAAAAGC TGATTGGTTG 
GATAGCATAA GACCACAAAA AGAAGGAGAC TTCAGAAAGG AGATTAACAA GTGGTGGAAT 
AACCTAAGTG ATGGCCAGCG GACTGTGACA GGTATTATAG CTGCAAATGT CCTTGTATTC 
TGTTTATGGA GAGTACCTTC TCTGCAGCGG ACAATGATCA GATATTTCAC ATCGAATCCA 
GCCTCAAGTG TTATTTCCAA TTTTGTCAGT TACGTGGGTA AAGTTGCCAC AGGAAGATAT 
GGACCATCAC TTGGTGCAGC CCTGAAAGCC ATTATCGCCA TGGATACAGC AGGAATGATC 
CTGGGATGGA AATTTTTTGA TCATGCGGCA CATCTTGGGG GAGCTCTTTT TGGAATGATC 
TCCCTCTACA CCTGGCGCCT CGCCTGCTGC CTGCTGGGAC ATGGCCTGGC CTGCTCAGCT 
GACCTGCTGC CACTTCTAGG CAGCCGTCAT GTCACTTTGC TACAACTTCA AGCTAAGACA 
GGCAATGTTT TGGGAGATGA ATCTGTTTTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PARL ( XM_017006803.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862292.1 Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X11, mRNA.

Price & Availability↑

CloneID	OHu94356
Clone ID Related Accession (Same CDS sequence)	XM_017006803.1
Accession Version	XM_017006803.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	presenilins-associated rhomboid-like protein, mitochondrial isoform X7
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAGTGTTA TTTCCAATTT TGTCAGTTAC 
GTGGGTAAAG TTGCCACAGG AAGATATGGA CCATCACTTG GTGCATCTGG TGCCATCATG 
ACAGTCCTCG CAGCTGTCTG CACTAAGATC CCAGAAGGGA GGCTTGCCAT TATTTTCCTT 
CCGATGTTCA CGTTCACAGC AGGGAATGCC CTGAAAGCCA TTATCGCCAT GGATACAGCA 
GGAATGATCC TGGGATGGAA ATTTTTTGAT CATGCGGCAC ATCTTGGGGG AGCTCTTTTT 
GGAATGATCT CCCTCTACAC CTGGCGCCTC GCCTGCTGCC TGCTGGGACA TGGCCTGGCC 
TGCTCAGCTG ACCTGCTGCC ACTTCTAGGC AGCCGTCATG TCACTTTGCT ACAACTTCAA 
GCTAAGACAG GCAATGTTTT GGGAGATGAA TCTGTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862292.1
CDS	683..1144
Translation	MIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF

Target ORF information:

RefSeq Version	XM_017006803.1
Organism	Homo sapiens(human)
Definition	Homo sapiens presenilin associated rhomboid like (PARL), transcript variant X11, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006803.1

ORF Insert Sequence:

ATGATCAGAT ATTTCACATC GAATCCAGCC TCAAGTGTTA TTTCCAATTT TGTCAGTTAC 
GTGGGTAAAG TTGCCACAGG AAGATATGGA CCATCACTTG GTGCATCTGG TGCCATCATG 
ACAGTCCTCG CAGCTGTCTG CACTAAGATC CCAGAAGGGA GGCTTGCCAT TATTTTCCTT 
CCGATGTTCA CGTTCACAGC AGGGAATGCC CTGAAAGCCA TTATCGCCAT GGATACAGCA 
GGAATGATCC TGGGATGGAA ATTTTTTGAT CATGCGGCAC ATCTTGGGGG AGCTCTTTTT 
GGAATGATCT CCCTCTACAC CTGGCGCCTC GCCTGCTGCC TGCTGGGACA TGGCCTGGCC 
TGCTCAGCTG ACCTGCTGCC ACTTCTAGGC AGCCGTCATG TCACTTTGCT ACAACTTCAA 
GCTAAGACAG GCAATGTTTT GGGAGATGAA TCTGTTTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria.
The EMBO journal(2018 Jan)
Saita S,Tatsuta T,Lampe PA,K?nig T,Ohba Y,Langer T

Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese.
Investigative ophthalmology & visual science58(10)4384?4389(2017 08)
Tang FY,Ma L,Tam POS,Pang CP,Tham CCY,Chen LJ

Role of PARL-PINK1-Parkin pathway in adipocyte differentiation.
Metabolism: clinical and experimental721-17(2017 Jul)
Shiau MY,Lee PS,Huang YJ,Yang CP,Hsiao CW,Chang KY,Chen HW,Chang YH

PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
Nature cell biology19(4)318-328(2017 Apr)
Saita S,Nolte H,Fiedler KU,Kashkar H,Venne AS,Zahedi RP,Kr?ger M,Langer T

The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism.
Cell reports18(6)1458-1472(2017 Feb)
Shi G,McQuibban GA

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

PARL cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼