POU4F1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	POU4F1
Entrez Gene ID	5457
Full Name	POU class 4 homeobox 1
Synonyms	BRN3A,Oct-T1,RDC-1,brn-3A
General protein information	Preferred Names POU class 4 homeobox 1 Names POU domain, class 4, transcription factor 1 brain-3A brain-specific homeobox/POU domain protein 3A homeobox/POU domain protein RDC-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q31.1
Summary	This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012].
Disorder MIM:	601632

mRNA and Protein(s)

mRNA	Protein	Name
NM_006237.3	NP_006228.3	POU domain, class 4, transcription factor 1
NM_006237.4	NP_006228.3	POU domain, class 4, transcription factor 1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	pou4f1	NP_958442.1
Mus musculus (house mouse)	Pou4f1	NP_035273.3
Homo sapiens (human)	POU4F1	NP_006228.3
Pan troglodytes (chimpanzee)	POU4F1	XP_003314220.1
Rattus norvegicus (Norway rat)	Pou4f1	XP_006252496.1
Xenopus tropicalis (tropical clawed frog)	LOC100488759	XP_002931972.1

Gene Ontology
Bibliography

Related articles in PubMed

Facial nerve stimulation following cochlear implantation for X-linked stapes gusher syndrome leading to identification of a novel POU3F4 mutation.
Wester JL, Merna C, Peng KA, Lewis R, Sepahdari AR, Ishiyama G, Hosokawa K, Kumakawa K, Ishiyama A
International journal of pediatric otorhinolaryngology91121-123(2016 Dec)

The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival.
Hohenauer T, Berking C, Schmidt A, Haferkamp S, Senft D, Kammerbauer C, Fraschka S, Graf SA, Irmler M, Beckers J, Flaig M, Aigner A, H?bel S, Hoffmann F, Hermeking H, Rothenfusser S, Endres S, Ruzicka T, Besch R
EMBO molecular medicine5(6)919-34(2013 Jun)

RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors.
Zhang L, Wahlin K, Li Y, Masuda T, Yang Z, Zack DJ, Esumi N
Molecular vision191371-86(2013)

Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.
Faryna M, Konermann C, Aulmann S, Bermejo JL, Brugger M, Diederichs S, Rom J, Weichenhan D, Claus R, Rehli M, Schirmacher P, Sinn HP, Plass C, Gerhauser C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology26(12)4937-50(2012 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We report a case of a nine-year-old male who presented with facial nerve stimulation four years after cochlear implantation. A dilated internal auditory meatus was revealed. Genetic analysis demonstrated X-linked deafness type 2 (DFNX2) caused by a novel c.769C T nucleotide change in the POU domain, class 3, transcription factor 4 gene
Title: Facial nerve stimulation following cochlear implantation for X-linked stapes gusher syndrome leading to identification of a novel POU3F4 mutation.

Brn3a cooperates with activated RAS/RAF signalling by reducing oncogene-induced senescence in melanocytic tumourigenesis.
Title: The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival.

Data indicate that median methylation levels of BCAN, HOXD1, KCTD8, KLF11, NXPH1, POU4F1, SIM1, and TCF7L1 were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis.
Title: Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.

PoU4F1 is highly expressed in t(8;21) samples, with AML/ETO appearning to promote some BRN3A expression
Title: AML1/ETO and POU4F1 synergy drives B-lymphoid gene expression typical of t(8;21) acute myeloid leukemia.

BRN3A possesses anti-apoptotic property, and considering the above results, it may be regarded as the key component in promoting tumorigenic growth in the uterine cervical cells.
Title: Molecular analysis of oncogenicity of the transcription factor, BRN3A, in cervical cancer cells.

The following POU4F1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POU4F1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30783	NM_006237.4 Latest version!	Homo sapiens POU class 4 homeobox 1 (POU4F1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu30783	NM_006237.3	Homo sapiens POU class 4 homeobox 1 (POU4F1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

POU4F1 ( NM_006237.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006228.3 Homo sapiens POU class 4 homeobox 1 (POU4F1), mRNA.

Price & Availability↑

CloneID	OHu30783
Clone ID Related Accession (Same CDS sequence)	NM_006237.3 , NM_006237.4
Accession Version	NM_006237.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	POU domain, class 4, transcription factor 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L20433.1, AL445209.4, BM714015.1, N74107.1 and BM726529.1. On or before Nov 22, 2006 this sequence version replaced XM_001133287.1, XM_001127734.1, NM_006237.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L20433.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGTCCA TGAACAGCAA GCAGCCTCAC TTTGCCATGC ATCCCACCCT CCCTGAGCAC 
AAGTACCCGT CGCTGCACTC CAGCTCCGAG GCCATCCGGC GGGCCTGCCT GCCCACGCCG 
CCGCTGCAGA GCAACCTCTT CGCCAGCCTG GACGAGACGC TGCTGGCGCG GGCCGAGGCG 
CTGGCGGCCG TGGACATCGC CGTGTCCCAG GGCAAGAGCC ATCCTTTCAA GCCGGACGCC 
ACGTACCACA CGATGAACAG CGTGCCGTGC ACGTCCACTT CCACGGTGCC TCTGGCGCAC 
CACCACCACC ACCACCACCA CCACCAGGCG CTCGAACCCG GCGATCTGCT GGACCACATC 
TCCTCGCCGT CGCTCGCGCT CATGGCCGGC GCGGGCGGCG CGGGCGCGGC GGCCGGCGGC 
GGCGGCGCCC ACGACGGCCC GGGGGGCGGT GGCGGCCCGG GCGGCGGCGG CGGCCCGGGC 
GGCGGCCCCG GGGGAGGCGG CGGTGGCGGC CCGGGGGGCG GCGGCGGCGG CCCGGGCGGC 
GGGCTCCTGG GCGGCTCCGC GCACCCTCAC CCGCATATGC ACAGCCTGGG CCACCTGTCG 
CACCCCGCGG CGGCGGCCGC CATGAACATG CCGTCCGGGC TGCCGCACCC CGGGCTGGTG 
GCGGCGGCGG CGCACCACGG CGCGGCAGCG GCAGCGGCGG CGGCGGCGGC CGGGCAGGTG 
GCAGCGGCAT CGGCGGCGGC GGCCGTGGTG GGCGCAGCGG GCCTGGCGTC CATCTGCGAC 
TCGGACACGG ACCCGCGCGA GCTCGAGGCG TTCGCGGAGC GCTTCAAGCA GCGGCGCATC 
AAGCTGGGCG TGACGCAGGC CGACGTGGGC TCGGCGCTGG CCAACCTCAA GATCCCGGGC 
GTGGGCTCAC TCAGCCAGAG CACCATCTGC AGGTTCGAGT CGCTCACGCT CTCGCACAAC 
AACATGATCG CGCTCAAGCC CATCCTGCAG GCGTGGCTCG AGGAGGCCGA GGGCGCCCAG 
CGCGAGAAAA TGAACAAGCC TGAGCTCTTC AACGGCGGCG AGAAGAAGCG CAAGCGGACT 
TCCATCGCCG CGCCCGAGAA GCGCTCCCTC GAGGCCTACT TCGCCGTGCA GCCCCGGCCC 
TCGTCCGAGA AGATCGCCGC CATCGCCGAG AAACTGGACC TCAAAAAGAA CGTGGTGCGG 
GTGTGGTTTT GCAACCAGAG ACAGAAGCAG AAGCGGATGA AATTCTCTGC CACTTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006228.3
CDS	235..1494
Translation	MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY

Target ORF information:

RefSeq Version	NM_006237.3
Organism	Homo sapiens(human)
Definition	Homo sapiens POU class 4 homeobox 1 (POU4F1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006237.3

ORF Insert Sequence:

ATGATGTCCA TGAACAGCAA GCAGCCTCAC TTTGCCATGC ATCCCACCCT CCCTGAGCAC 
AAGTACCCGT CGCTGCACTC CAGCTCCGAG GCCATCCGGC GGGCCTGCCT GCCCACGCCG 
CCGCTGCAGA GCAACCTCTT CGCCAGCCTG GACGAGACGC TGCTGGCGCG GGCCGAGGCG 
CTGGCGGCCG TGGACATCGC CGTGTCCCAG GGCAAGAGCC ATCCTTTCAA GCCGGACGCC 
ACGTACCACA CGATGAACAG CGTGCCGTGC ACGTCCACTT CCACGGTGCC TCTGGCGCAC 
CACCACCACC ACCACCACCA CCACCAGGCG CTCGAACCCG GCGATCTGCT GGACCACATC 
TCCTCGCCGT CGCTCGCGCT CATGGCCGGC GCGGGCGGCG CGGGCGCGGC GGCCGGCGGC 
GGCGGCGCCC ACGACGGCCC GGGGGGCGGT GGCGGCCCGG GCGGCGGCGG CGGCCCGGGC 
GGCGGCCCCG GGGGAGGCGG CGGTGGCGGC CCGGGGGGCG GCGGCGGCGG CCCGGGCGGC 
GGGCTCCTGG GCGGCTCCGC GCACCCTCAC CCGCATATGC ACAGCCTGGG CCACCTGTCG 
CACCCCGCGG CGGCGGCCGC CATGAACATG CCGTCCGGGC TGCCGCACCC CGGGCTGGTG 
GCGGCGGCGG CGCACCACGG CGCGGCAGCG GCAGCGGCGG CGGCGGCGGC CGGGCAGGTG 
GCAGCGGCAT CGGCGGCGGC GGCCGTGGTG GGCGCAGCGG GCCTGGCGTC CATCTGCGAC 
TCGGACACGG ACCCGCGCGA GCTCGAGGCG TTCGCGGAGC GCTTCAAGCA GCGGCGCATC 
AAGCTGGGCG TGACGCAGGC CGACGTGGGC TCGGCGCTGG CCAACCTCAA GATCCCGGGC 
GTGGGCTCAC TCAGCCAGAG CACCATCTGC AGGTTCGAGT CGCTCACGCT CTCGCACAAC 
AACATGATCG CGCTCAAGCC CATCCTGCAG GCGTGGCTCG AGGAGGCCGA GGGCGCCCAG 
CGCGAGAAAA TGAACAAGCC TGAGCTCTTC AACGGCGGCG AGAAGAAGCG CAAGCGGACT 
TCCATCGCCG CGCCCGAGAA GCGCTCCCTC GAGGCCTACT TCGCCGTGCA GCCCCGGCCC 
TCGTCCGAGA AGATCGCCGC CATCGCCGAG AAACTGGACC TCAAAAAGAA CGTGGTGCGG 
GTGTGGTTTT GCAACCAGAG ACAGAAGCAG AAGCGGATGA AATTCTCTGC CACTTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

POU4F1 ( NM_006237.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006228.3 Homo sapiens POU class 4 homeobox 1 (POU4F1), mRNA.

Price & Availability↑

CloneID	OHu30783
Clone ID Related Accession (Same CDS sequence)	NM_006237.3 , NM_006237.4
Accession Version	NM_006237.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-16
Organism	Homo sapiens(human)
Product	POU domain, class 4, transcription factor 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L20433.1, AL445209.4, BM714015.1, N74107.1 and BM726529.1. On Nov 22, 2018 this sequence version replaced NM_006237.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L20433.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377208.7/ ENSP00000366413.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATGTCCA TGAACAGCAA GCAGCCTCAC TTTGCCATGC ATCCCACCCT CCCTGAGCAC 
AAGTACCCGT CGCTGCACTC CAGCTCCGAG GCCATCCGGC GGGCCTGCCT GCCCACGCCG 
CCGCTGCAGA GCAACCTCTT CGCCAGCCTG GACGAGACGC TGCTGGCGCG GGCCGAGGCG 
CTGGCGGCCG TGGACATCGC CGTGTCCCAG GGCAAGAGCC ATCCTTTCAA GCCGGACGCC 
ACGTACCACA CGATGAACAG CGTGCCGTGC ACGTCCACTT CCACGGTGCC TCTGGCGCAC 
CACCACCACC ACCACCACCA CCACCAGGCG CTCGAACCCG GCGATCTGCT GGACCACATC 
TCCTCGCCGT CGCTCGCGCT CATGGCCGGC GCGGGCGGCG CGGGCGCGGC GGCCGGCGGC 
GGCGGCGCCC ACGACGGCCC GGGGGGCGGT GGCGGCCCGG GCGGCGGCGG CGGCCCGGGC 
GGCGGCCCCG GGGGAGGCGG CGGTGGCGGC CCGGGGGGCG GCGGCGGCGG CCCGGGCGGC 
GGGCTCCTGG GCGGCTCCGC GCACCCTCAC CCGCATATGC ACAGCCTGGG CCACCTGTCG 
CACCCCGCGG CGGCGGCCGC CATGAACATG CCGTCCGGGC TGCCGCACCC CGGGCTGGTG 
GCGGCGGCGG CGCACCACGG CGCGGCAGCG GCAGCGGCGG CGGCGGCGGC CGGGCAGGTG 
GCAGCGGCAT CGGCGGCGGC GGCCGTGGTG GGCGCAGCGG GCCTGGCGTC CATCTGCGAC 
TCGGACACGG ACCCGCGCGA GCTCGAGGCG TTCGCGGAGC GCTTCAAGCA GCGGCGCATC 
AAGCTGGGCG TGACGCAGGC CGACGTGGGC TCGGCGCTGG CCAACCTCAA GATCCCGGGC 
GTGGGCTCAC TCAGCCAGAG CACCATCTGC AGGTTCGAGT CGCTCACGCT CTCGCACAAC 
AACATGATCG CGCTCAAGCC CATCCTGCAG GCGTGGCTCG AGGAGGCCGA GGGCGCCCAG 
CGCGAGAAAA TGAACAAGCC TGAGCTCTTC AACGGCGGCG AGAAGAAGCG CAAGCGGACT 
TCCATCGCCG CGCCCGAGAA GCGCTCCCTC GAGGCCTACT TCGCCGTGCA GCCCCGGCCC 
TCGTCCGAGA AGATCGCCGC CATCGCCGAG AAACTGGACC TCAAAAAGAA CGTGGTGCGG 
GTGTGGTTTT GCAACCAGAG ACAGAAGCAG AAGCGGATGA AATTCTCTGC CACTTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006228.3
CDS	227..1486
Translation	MMSMNSKQPHFAMHPTLPEHKYPSLHSSSEAIRRACLPTPPLQSNLFASLDETLLARAEALAAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY

Target ORF information:

RefSeq Version	NM_006237.4
Organism	Homo sapiens(human)
Definition	Homo sapiens POU class 4 homeobox 1 (POU4F1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006237.4

ORF Insert Sequence:

ATGATGTCCA TGAACAGCAA GCAGCCTCAC TTTGCCATGC ATCCCACCCT CCCTGAGCAC 
AAGTACCCGT CGCTGCACTC CAGCTCCGAG GCCATCCGGC GGGCCTGCCT GCCCACGCCG 
CCGCTGCAGA GCAACCTCTT CGCCAGCCTG GACGAGACGC TGCTGGCGCG GGCCGAGGCG 
CTGGCGGCCG TGGACATCGC CGTGTCCCAG GGCAAGAGCC ATCCTTTCAA GCCGGACGCC 
ACGTACCACA CGATGAACAG CGTGCCGTGC ACGTCCACTT CCACGGTGCC TCTGGCGCAC 
CACCACCACC ACCACCACCA CCACCAGGCG CTCGAACCCG GCGATCTGCT GGACCACATC 
TCCTCGCCGT CGCTCGCGCT CATGGCCGGC GCGGGCGGCG CGGGCGCGGC GGCCGGCGGC 
GGCGGCGCCC ACGACGGCCC GGGGGGCGGT GGCGGCCCGG GCGGCGGCGG CGGCCCGGGC 
GGCGGCCCCG GGGGAGGCGG CGGTGGCGGC CCGGGGGGCG GCGGCGGCGG CCCGGGCGGC 
GGGCTCCTGG GCGGCTCCGC GCACCCTCAC CCGCATATGC ACAGCCTGGG CCACCTGTCG 
CACCCCGCGG CGGCGGCCGC CATGAACATG CCGTCCGGGC TGCCGCACCC CGGGCTGGTG 
GCGGCGGCGG CGCACCACGG CGCGGCAGCG GCAGCGGCGG CGGCGGCGGC CGGGCAGGTG 
GCAGCGGCAT CGGCGGCGGC GGCCGTGGTG GGCGCAGCGG GCCTGGCGTC CATCTGCGAC 
TCGGACACGG ACCCGCGCGA GCTCGAGGCG TTCGCGGAGC GCTTCAAGCA GCGGCGCATC 
AAGCTGGGCG TGACGCAGGC CGACGTGGGC TCGGCGCTGG CCAACCTCAA GATCCCGGGC 
GTGGGCTCAC TCAGCCAGAG CACCATCTGC AGGTTCGAGT CGCTCACGCT CTCGCACAAC 
AACATGATCG CGCTCAAGCC CATCCTGCAG GCGTGGCTCG AGGAGGCCGA GGGCGCCCAG 
CGCGAGAAAA TGAACAAGCC TGAGCTCTTC AACGGCGGCG AGAAGAAGCG CAAGCGGACT 
TCCATCGCCG CGCCCGAGAA GCGCTCCCTC GAGGCCTACT TCGCCGTGCA GCCCCGGCCC 
TCGTCCGAGA AGATCGCCGC CATCGCCGAG AAACTGGACC TCAAAAAGAA CGTGGTGCGG 
GTGTGGTTTT GCAACCAGAG ACAGAAGCAG AAGCGGATGA AATTCTCTGC CACTTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Facial nerve stimulation following cochlear implantation for X-linked stapes gusher syndrome leading to identification of a novel POU3F4 mutation.
International journal of pediatric otorhinolaryngology91121-123(2016 Dec)
Wester JL,Merna C,Peng KA,Lewis R,Sepahdari AR,Ishiyama G,Hosokawa K,Kumakawa K,Ishiyama A

The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival.
EMBO molecular medicine5(6)919-34(2013 Jun)
Hohenauer T,Berking C,Schmidt A,Haferkamp S,Senft D,Kammerbauer C,Fraschka S,Graf SA,Irmler M,Beckers J,Flaig M,Aigner A,H?bel S,Hoffmann F,Hermeking H,Rothenfusser S,Endres S,Ruzicka T,Besch R

RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors.
Molecular vision191371-86(2013)
Zhang L,Wahlin K,Li Y,Masuda T,Yang Z,Zack DJ,Esumi N

Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology26(12)4937-50(2012 Dec)
Faryna M,Konermann C,Aulmann S,Bermejo JL,Brugger M,Diederichs S,Rom J,Weichenhan D,Claus R,Rehli M,Schirmacher P,Sinn HP,Plass C,Gerhauser C

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POU4F1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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