PEX7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PEX7
Entrez Gene ID	5191
Full Name	peroxisomal biogenesis factor 7
Synonyms	PBD9B,PTS2R,RCDP1,RD
General protein information	Preferred Names peroxisomal biogenesis factor 7 Names peroxisomal biogenesis factor 7 PTS2 receptor peroxin-7 peroxisomal PTS2 receptor peroxisomal targeting signal 2 receptor peroxisome targeting signal 2 receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q23.3
Summary	This gene encodes the cytosolic receptor for the set of peroxisomal matrix enzymes targeted to the organelle by the peroxisome targeting signal 2 (PTS2). Defects in this gene cause peroxisome biogenesis disorders (PBDs), which are characterized by multiple defects in peroxisome function. There are at least 14 complementation groups for PBDs, with more than one phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene have been associated with PBD complementation group 11 (PBD-CG11) disorders, rhizomelic chondrodysplasia punctata type 1 (RCDP1), and Refsum disease (RD). [provided by RefSeq, Oct 2008].
Disorder MIM:	601757
Disorder Html:	Rhizomelic chondrodysplasia punctata, type 1, 215100 (3); Peroxisome biogenesis disorder 9B, 614879 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_006715502.1	XP_006715565.1	peroxisomal biogenesis factor 7 isoform X2
NM_000288.3	NP_000279.1	peroxisomal biogenesis factor 7
XM_017010934.2	XP_016866423.1	peroxisomal biogenesis factor 7 isoform X3
XM_017010934.1	XP_016866423.1	peroxisomal biogenesis factor 7 isoform X3
NM_000288.4	NP_000279.1	peroxisomal biogenesis factor 7
XM_005267019.4	XP_005267076.1	peroxisomal biogenesis factor 7 isoform X1
XM_006715502.2	XP_006715565.1	peroxisomal biogenesis factor 7 isoform X2

Pathways from BioSystems

Homologies

	PEX7	XP_001097630.1
Canis lupus familiaris (dog)	PEX7	XP_541117.2
Mus musculus (house mouse)	Pex7	NP_032848.1
Oryza sativa (rice)	Os02g0245100	NP_001046419.1
Pan troglodytes (chimpanzee)	PEX7	XP_518763.2
Rattus norvegicus (Norway rat)	Pex7	NP_001029319.1
Danio rerio (zebrafish)	pex7	NP_001013550.1
Xenopus tropicalis (tropical clawed frog)	pex7	NP_001015954.1
Gallus gallus (chicken)	PEX7	NP_001264638.1
Bos taurus (cattle)	PEX7	NP_001070358.1
Drosophila melanogaster (fruit fly)	Pex7	NP_001137914.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006264	XP_001688840.1
Homo sapiens (human)	PEX7	NP_000279.1
Arabidopsis thaliana (thale cress)	PEX7	NP_174220.1

Gene Ontology
Bibliography

Related articles in PubMed

Peroxisomal abnormalities in the immortalized human hepatocyte (IHH) cell line.
Klouwer FC, Koster J, Ferdinandusse S, Waterham HR
Histochemistry and cell biology147(4)537-541(2017 Apr)

Revisiting the intraperoxisomal pathway of mammalian PEX7.
Rodrigues TA, Grou CP, Azevedo JE
Scientific reports511806(2015 Jul)

Rhizomelic Chondrodysplasia Punctata Type 1 Caused by a Novel Mutation in the PEX7 Gene.
?im A, Co?kun S, G?r?kmez O, Y?ksel H, Uluca ?, Pietro ED, Plourde F, Braverman NE
Journal of clinical research in pediatric endocrinology7(1)69-72(2015 Mar)

Mechanistic insights into PTS2-mediated peroxisomal protein import: the co-receptor PEX5L drastically increases the interaction strength between the cargo protein and the receptor PEX7.
Kunze M, Malkani N, Maurer-Stroh S, Wiesinger C, Schmid JA, Berger J
The Journal of biological chemistry290(8)4928-40(2015 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This revealed a marked plasmalogen deficiency and a deficient fatty acid alpha-oxidation in the IHH cells, due to a defect of PEX7, a cytosolic receptor protein required for peroxisomal import of a subset of peroxisomal proteins.
Title: Peroxisomal abnormalities in the immortalized human hepatocyte (IHH) cell line.

our data suggest that insertion of the trimeric PEX5-PEX7-PTS2 protein complex into the DTM is probably accompanied by conformational alterations in PEX5 to allow release of the PTS2 protein into the organelle matrix
Title: Revisiting the intraperoxisomal pathway of mammalian PEX7.

Mutation in the PEX7 Gene is associated with Rhizomelic Chondrodysplasia Punctata Type 1.
Title: Rhizomelic Chondrodysplasia Punctata Type 1 Caused by a Novel Mutation in the PEX7 Gene.

the sequential formation of a highly stable trimeric complex involving cargo protein, PEX7 and PEX5L stabilizes cargo binding and is a prerequisite for PTS2-mediated peroxisomal import.
Title: Mechanistic insights into PTS2-mediated peroxisomal protein import: the co-receptor PEX5L drastically increases the interaction strength between the cargo protein and the receptor PEX7.

dysfunctional Pex7p, including mutants from RCDP patients, is degraded by a ubiquitin-dependent proteasomal pathway involving the CRL4A (Cullin4A-RING ubiquitin ligase) complex.
Title: CUL4A-DDB1-Rbx1 E3 ligase controls the quality of the PTS2 receptor Pex7p.

The following PEX7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PEX7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26068	NM_000288.4 Latest version!	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu40851	XM_005267019.4 Latest version!	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu40852	XM_006715502.2 Latest version!	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu40853	XM_017010934.2 Latest version!	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu40853	XM_017010934.1	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu26068	NM_000288.3	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu40852	XM_006715502.1	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PEX7 ( NM_000288.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000279.1 Homo sapiens peroxisomal biogenesis factor 7 (PEX7), mRNA.

Price & Availability↑

CloneID	OHu26068
Clone ID Related Accession (Same CDS sequence)	NM_000288.3 , NM_000288.4
Accession Version	NM_000288.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	peroxisomal biogenesis factor 7
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP246238.1, U76560.1 and BQ011494.1. This sequence is a reference standard in the RefSeqGene project. On Sep 4, 2008 this sequence version replaced NM_000288.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279826.6424.1, SRR1163658.108808.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGG TGTATAGTGT TGATTGGAGC 
CAAACCAGAG GTGAACAGCT TGTGGTGTCT GGCTCATGGG ATCAAACTGT CAAATTGTGG 
GATCCAACTG TTGGAAAGTC TCTGTGCACC TTTAGAGGCC ATGAAAGTAT TATTTATAGC 
ACAATCTGGT CTCCCCACAT CCCTGGTTGT TTTGCTTCAG CCTCAGGTGA TCAGACTCTG 
AGAATATGGG ATGTGAAGGC AGCAGGAGTA AGAATCGTGA TTCCTGCACA TCAGGCAGAA 
ATCTTGAGTT GTGACTGGTG TAAATACAAT GAGAATTTGC TGGTGACCGG GGCGGTTGAC 
TGTAGTTTGA GAGGCTGGGA CTTAAGGAAT GTACGACAAC CAGTGTTTGA ACTTCTTGGT 
CATACCTATG CTATTAGGAG GGTGAAATTT TCACCATTTC ATGCTTCTGT GCTGGCCTCT 
TGCTCGTATG ATTTTACTGT AAGATTCTGG AACTTTTCAA AGCCTGACTC TCTTCTTGAA 
ACAGTGGAGC ATCATACAGA GTTTACTTGT GGTTTAGACT TCAGTCTTCA GAGCCCCACT 
CAGGTGGCTG ACTGTTCTTG GGATGAAACA ATAAAGATCT ATGACCCTGC TTGTCTTACT 
ATTCCTGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000279.1
CDS	103..1074
Translation	MSAVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA

Target ORF information:

RefSeq Version	NM_000288.3
Organism	Homo sapiens(human)
Definition	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000288.3

ORF Insert Sequence:

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGG TGTATAGTGT TGATTGGAGC 
CAAACCAGAG GTGAACAGCT TGTGGTGTCT GGCTCATGGG ATCAAACTGT CAAATTGTGG 
GATCCAACTG TTGGAAAGTC TCTGTGCACC TTTAGAGGCC ATGAAAGTAT TATTTATAGC 
ACAATCTGGT CTCCCCACAT CCCTGGTTGT TTTGCTTCAG CCTCAGGTGA TCAGACTCTG 
AGAATATGGG ATGTGAAGGC AGCAGGAGTA AGAATCGTGA TTCCTGCACA TCAGGCAGAA 
ATCTTGAGTT GTGACTGGTG TAAATACAAT GAGAATTTGC TGGTGACCGG GGCGGTTGAC 
TGTAGTTTGA GAGGCTGGGA CTTAAGGAAT GTACGACAAC CAGTGTTTGA ACTTCTTGGT 
CATACCTATG CTATTAGGAG GGTGAAATTT TCACCATTTC ATGCTTCTGT GCTGGCCTCT 
TGCTCGTATG ATTTTACTGT AAGATTCTGG AACTTTTCAA AGCCTGACTC TCTTCTTGAA 
ACAGTGGAGC ATCATACAGA GTTTACTTGT GGTTTAGACT TCAGTCTTCA GAGCCCCACT 
CAGGTGGCTG ACTGTTCTTG GGATGAAACA ATAAAGATCT ATGACCCTGC TTGTCTTACT 
ATTCCTGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PEX7 ( NM_000288.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000279.1 Homo sapiens peroxisomal biogenesis factor 7 (PEX7), mRNA.

Price & Availability↑

CloneID	OHu26068
Clone ID Related Accession (Same CDS sequence)	NM_000288.3 , NM_000288.4
Accession Version	NM_000288.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 972bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	peroxisomal biogenesis factor 7
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP246238.1, U76560.1 and BQ011494.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_000288.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279826.6424.1, U88871.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000318471.5/ ENSP00000315680.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGG TGTATAGTGT TGATTGGAGC 
CAAACCAGAG GTGAACAGCT TGTGGTGTCT GGCTCATGGG ATCAAACTGT CAAATTGTGG 
GATCCAACTG TTGGAAAGTC TCTGTGCACC TTTAGAGGCC ATGAAAGTAT TATTTATAGC 
ACAATCTGGT CTCCCCACAT CCCTGGTTGT TTTGCTTCAG CCTCAGGTGA TCAGACTCTG 
AGAATATGGG ATGTGAAGGC AGCAGGAGTA AGAATCGTGA TTCCTGCACA TCAGGCAGAA 
ATCTTGAGTT GTGACTGGTG TAAATACAAT GAGAATTTGC TGGTGACCGG GGCGGTTGAC 
TGTAGTTTGA GAGGCTGGGA CTTAAGGAAT GTACGACAAC CAGTGTTTGA ACTTCTTGGT 
CATACCTATG CTATTAGGAG GGTGAAATTT TCACCATTTC ATGCTTCTGT GCTGGCCTCT 
TGCTCGTATG ATTTTACTGT AAGATTCTGG AACTTTTCAA AGCCTGACTC TCTTCTTGAA 
ACAGTGGAGC ATCATACAGA GTTTACTTGT GGTTTAGACT TCAGTCTTCA GAGCCCCACT 
CAGGTGGCTG ACTGTTCTTG GGATGAAACA ATAAAGATCT ATGACCCTGC TTGTCTTACT 
ATTCCTGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000279.1
CDS	75..1046
Translation	MSAVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA

Target ORF information:

RefSeq Version	NM_000288.4
Organism	Homo sapiens(human)
Definition	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000288.4

ORF Insert Sequence:

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGG TGTATAGTGT TGATTGGAGC 
CAAACCAGAG GTGAACAGCT TGTGGTGTCT GGCTCATGGG ATCAAACTGT CAAATTGTGG 
GATCCAACTG TTGGAAAGTC TCTGTGCACC TTTAGAGGCC ATGAAAGTAT TATTTATAGC 
ACAATCTGGT CTCCCCACAT CCCTGGTTGT TTTGCTTCAG CCTCAGGTGA TCAGACTCTG 
AGAATATGGG ATGTGAAGGC AGCAGGAGTA AGAATCGTGA TTCCTGCACA TCAGGCAGAA 
ATCTTGAGTT GTGACTGGTG TAAATACAAT GAGAATTTGC TGGTGACCGG GGCGGTTGAC 
TGTAGTTTGA GAGGCTGGGA CTTAAGGAAT GTACGACAAC CAGTGTTTGA ACTTCTTGGT 
CATACCTATG CTATTAGGAG GGTGAAATTT TCACCATTTC ATGCTTCTGT GCTGGCCTCT 
TGCTCGTATG ATTTTACTGT AAGATTCTGG AACTTTTCAA AGCCTGACTC TCTTCTTGAA 
ACAGTGGAGC ATCATACAGA GTTTACTTGT GGTTTAGACT TCAGTCTTCA GAGCCCCACT 
CAGGTGGCTG ACTGTTCTTG GGATGAAACA ATAAAGATCT ATGACCCTGC TTGTCTTACT 
ATTCCTGCTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PEX7 ( XM_005267019.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005267076.1 Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu40851
Clone ID Related Accession (Same CDS sequence)	XM_005267019.4
Accession Version	XM_005267019.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	peroxisomal biogenesis factor 7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005267019.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCACACAT TCGCAAGCTG TGGAACCCTA CTAATATTGG ATCCAGATGA AGCTGGGCTA 
AGGCTTTTTA GAAGCTTTGA CTGGAATGAT GGTTTGTTTG ATGTGACTTG GAGTGAGAAC 
AACGAACATG TCCTCATCAC CTGTAGTGGC GATGGCTCGC TGCAGCTCTG GGACACTGCC 
AAAGCTGCAG GGCCACTGCA AGTCTATAAA GAACACGCTC AGGAGGTGTA TAGTGTTGAT 
TGGAGCCAAA CCAGAGGTGA ACAGCTTGTG GTGTCTGGCT CATGGGATCA AACTGTCAAA 
TTGTGGGATC CAACTGTTGG AAAGTCTCTG TGCACCTTTA GAGGCCATGA AAGTATTATT 
TATAGCACAA TCTGGTCTCC CCACATCCCT GGTTGTTTTG CTTCAGCCTC AGGTGATCAG 
ACTCTGAGAA TATGGGATGT GAAGGCAGCA GGAGTAAGAA TCGTGATTCC TGCACATCAG 
GCAGAAATCT TGAGTTGTGA CTGGTGTAAA TACAATGAGA ATTTGCTGGT GACCGGGGCG 
GTTGACTGTA GTTTGAGAGG CTGGGACTTA AGGAATGTAC GACAACCAGT GTTTGAACTT 
CTTGGTCATA CCTATGCTAT TAGGAGGGTG AAATTTTCAC CATTTCATGC TTCTGTGCTG 
GCCTCTTGCT CGTATGATTT TACTGTAAGA TTCTGGAACT TTTCAAAGCC TGACTCTCTT 
CTTGAAACAG TGGAGCATCA TACAGAGTTT ACTTGTGGTT TAGACTTCAG TCTTCAGAGC 
CCCACTCAGG TGGCTGACTG TTCTTGGGAT GAAACAATAA AGATCTATGA CCCTGCTTGT 
CTTACTATTC CTGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005267076.1
CDS	497..1354
Translation	MHTFASCGTLLILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA

Target ORF information:

RefSeq Version	XM_005267019.4
Organism	Homo sapiens(human)
Definition	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005267019.4

ORF Insert Sequence:

ATGCACACAT TCGCAAGCTG TGGAACCCTA CTAATATTGG ATCCAGATGA AGCTGGGCTA 
AGGCTTTTTA GAAGCTTTGA CTGGAATGAT GGTTTGTTTG ATGTGACTTG GAGTGAGAAC 
AACGAACATG TCCTCATCAC CTGTAGTGGC GATGGCTCGC TGCAGCTCTG GGACACTGCC 
AAAGCTGCAG GGCCACTGCA AGTCTATAAA GAACACGCTC AGGAGGTGTA TAGTGTTGAT 
TGGAGCCAAA CCAGAGGTGA ACAGCTTGTG GTGTCTGGCT CATGGGATCA AACTGTCAAA 
TTGTGGGATC CAACTGTTGG AAAGTCTCTG TGCACCTTTA GAGGCCATGA AAGTATTATT 
TATAGCACAA TCTGGTCTCC CCACATCCCT GGTTGTTTTG CTTCAGCCTC AGGTGATCAG 
ACTCTGAGAA TATGGGATGT GAAGGCAGCA GGAGTAAGAA TCGTGATTCC TGCACATCAG 
GCAGAAATCT TGAGTTGTGA CTGGTGTAAA TACAATGAGA ATTTGCTGGT GACCGGGGCG 
GTTGACTGTA GTTTGAGAGG CTGGGACTTA AGGAATGTAC GACAACCAGT GTTTGAACTT 
CTTGGTCATA CCTATGCTAT TAGGAGGGTG AAATTTTCAC CATTTCATGC TTCTGTGCTG 
GCCTCTTGCT CGTATGATTT TACTGTAAGA TTCTGGAACT TTTCAAAGCC TGACTCTCTT 
CTTGAAACAG TGGAGCATCA TACAGAGTTT ACTTGTGGTT TAGACTTCAG TCTTCAGAGC 
CCCACTCAGG TGGCTGACTG TTCTTGGGAT GAAACAATAA AGATCTATGA CCCTGCTTGT 
CTTACTATTC CTGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PEX7 ( XM_006715502.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_006715565.1 Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu40852
Clone ID Related Accession (Same CDS sequence)	XM_006715502.1 , XM_006715502.2
Accession Version	XM_006715502.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	peroxisomal biogenesis factor 7 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGA ATTTGCTGGT GACCGGGGCG 
GTTGACTGTA GTTTGAGAGG CTGGGACTTA AGGAATGTAC GACAACCAGT GTTTGAACTT 
CTTGGTCATA CCTATGCTAT TAGGAGGGTG AAATTTTCAC CATTTCATGC TTCTGTGCTG 
GCCTCTTGCT CGTATGATTT TACTGTAAGA TTCTGGAACT TTTCAAAGCC TGACTCTCTT 
CTTGAAACAG TGGAGCATCA TACAGAGTTT ACTTGTGGTT TAGACTTCAG TCTTCAGAGC 
CCCACTCAGG TGGCTGACTG TTCTTGGGAT GAAACAATAA AGATCTATGA CCCTGCTTGT 
CTTACTATTC CTGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006715565.1
CDS	447..1124
Translation	MSAVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA

Target ORF information:

RefSeq Version	XM_006715502.1
Organism	Homo sapiens(human)
Definition	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006715502.1

ORF Insert Sequence:

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGA ATTTGCTGGT GACCGGGGCG 
GTTGACTGTA GTTTGAGAGG CTGGGACTTA AGGAATGTAC GACAACCAGT GTTTGAACTT 
CTTGGTCATA CCTATGCTAT TAGGAGGGTG AAATTTTCAC CATTTCATGC TTCTGTGCTG 
GCCTCTTGCT CGTATGATTT TACTGTAAGA TTCTGGAACT TTTCAAAGCC TGACTCTCTT 
CTTGAAACAG TGGAGCATCA TACAGAGTTT ACTTGTGGTT TAGACTTCAG TCTTCAGAGC 
CCCACTCAGG TGGCTGACTG TTCTTGGGAT GAAACAATAA AGATCTATGA CCCTGCTTGT 
CTTACTATTC CTGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PEX7 ( XM_006715502.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006715565.1 Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X2, mRNA.

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CloneID	OHu40852
Clone ID Related Accession (Same CDS sequence)	XM_006715502.1 , XM_006715502.2
Accession Version	XM_006715502.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	peroxisomal biogenesis factor 7 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006715502.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGA ATTTGCTGGT GACCGGGGCG 
GTTGACTGTA GTTTGAGAGG CTGGGACTTA AGGAATGTAC GACAACCAGT GTTTGAACTT 
CTTGGTCATA CCTATGCTAT TAGGAGGGTG AAATTTTCAC CATTTCATGC TTCTGTGCTG 
GCCTCTTGCT CGTATGATTT TACTGTAAGA TTCTGGAACT TTTCAAAGCC TGACTCTCTT 
CTTGAAACAG TGGAGCATCA TACAGAGTTT ACTTGTGGTT TAGACTTCAG TCTTCAGAGC 
CCCACTCAGG TGGCTGACTG TTCTTGGGAT GAAACAATAA AGATCTATGA CCCTGCTTGT 
CTTACTATTC CTGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006715565.1
CDS	773..1450
Translation	MSAVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA

Target ORF information:

RefSeq Version	XM_006715502.2
Organism	Homo sapiens(human)
Definition	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006715502.2

ORF Insert Sequence:

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGA ATTTGCTGGT GACCGGGGCG 
GTTGACTGTA GTTTGAGAGG CTGGGACTTA AGGAATGTAC GACAACCAGT GTTTGAACTT 
CTTGGTCATA CCTATGCTAT TAGGAGGGTG AAATTTTCAC CATTTCATGC TTCTGTGCTG 
GCCTCTTGCT CGTATGATTT TACTGTAAGA TTCTGGAACT TTTCAAAGCC TGACTCTCTT 
CTTGAAACAG TGGAGCATCA TACAGAGTTT ACTTGTGGTT TAGACTTCAG TCTTCAGAGC 
CCCACTCAGG TGGCTGACTG TTCTTGGGAT GAAACAATAA AGATCTATGA CCCTGCTTGT 
CTTACTATTC CTGCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PEX7 ( XM_017010934.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016866423.1 Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X3, mRNA.

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CloneID	OHu40853
Clone ID Related Accession (Same CDS sequence)	XM_017010934.2 , XM_017010934.1
Accession Version	XM_017010934.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	peroxisomal biogenesis factor 7 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017010934.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGG TGTATAGTGT TGATTGGAGC 
CAAACCAGAG GTGAACAGCT TGTGGTGTCT GGCTCATGGG ATCAAACTGT CAAATTGTGG 
GATCCAACTG TTGGAAAGTC TCTGTGCACC TTTAGAGGCC ATGAAAGTAT TATTTATAGC 
ACAATCTGGT CTCCCCACAT CCCTGGTTGT TTTGCTTCAG CCTCAGATTC TGGAACTTTT 
CAAAGCCTGA CTCTCTTCTT GAAACAGTGG AGCATCATAC AGAGTTTACT TGTGGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016866423.1
CDS	984..1583
Translation	MSAVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASDSGTFQSLTLFLKQWSIIQSLLVV

Target ORF information:

RefSeq Version	XM_017010934.2
Organism	Homo sapiens(human)
Definition	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010934.2

ORF Insert Sequence:

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGG TGTATAGTGT TGATTGGAGC 
CAAACCAGAG GTGAACAGCT TGTGGTGTCT GGCTCATGGG ATCAAACTGT CAAATTGTGG 
GATCCAACTG TTGGAAAGTC TCTGTGCACC TTTAGAGGCC ATGAAAGTAT TATTTATAGC 
ACAATCTGGT CTCCCCACAT CCCTGGTTGT TTTGCTTCAG CCTCAGATTC TGGAACTTTT 
CAAAGCCTGA CTCTCTTCTT GAAACAGTGG AGCATCATAC AGAGTTTACT TGTGGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PEX7 ( XM_017010934.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016866423.1 Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu40853
Clone ID Related Accession (Same CDS sequence)	XM_017010934.2 , XM_017010934.1
Accession Version	XM_017010934.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	peroxisomal biogenesis factor 7 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGG TGTATAGTGT TGATTGGAGC 
CAAACCAGAG GTGAACAGCT TGTGGTGTCT GGCTCATGGG ATCAAACTGT CAAATTGTGG 
GATCCAACTG TTGGAAAGTC TCTGTGCACC TTTAGAGGCC ATGAAAGTAT TATTTATAGC 
ACAATCTGGT CTCCCCACAT CCCTGGTTGT TTTGCTTCAG CCTCAGATTC TGGAACTTTT 
CAAAGCCTGA CTCTCTTCTT GAAACAGTGG AGCATCATAC AGAGTTTACT TGTGGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016866423.1
CDS	447..1046
Translation	MSAVCGGAARMLRTPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRSFDWNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASDSGTFQSLTLFLKQWSIIQSLLVV

Target ORF information:

RefSeq Version	XM_017010934.1
Organism	Homo sapiens(human)
Definition	Homo sapiens peroxisomal biogenesis factor 7 (PEX7), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017010934.1

ORF Insert Sequence:

ATGAGTGCGG TGTGCGGTGG AGCGGCGCGG ATGCTGCGGA CGCCGGGACG CCACGGCTAC 
GCCGCCGAGT TCTCCCCGTA CCTGCCGGGC CGCCTGGCCT GCGCCACCGC GCAGCACTAC 
GGCATCGCGG GCTGTGGAAC CCTACTAATA TTGGATCCAG ATGAAGCTGG GCTAAGGCTT 
TTTAGAAGCT TTGACTGGAA TGATGGTTTG TTTGATGTGA CTTGGAGTGA GAACAACGAA 
CATGTCCTCA TCACCTGTAG TGGCGATGGC TCGCTGCAGC TCTGGGACAC TGCCAAAGCT 
GCAGGGCCAC TGCAAGTCTA TAAAGAACAC GCTCAGGAGG TGTATAGTGT TGATTGGAGC 
CAAACCAGAG GTGAACAGCT TGTGGTGTCT GGCTCATGGG ATCAAACTGT CAAATTGTGG 
GATCCAACTG TTGGAAAGTC TCTGTGCACC TTTAGAGGCC ATGAAAGTAT TATTTATAGC 
ACAATCTGGT CTCCCCACAT CCCTGGTTGT TTTGCTTCAG CCTCAGATTC TGGAACTTTT 
CAAAGCCTGA CTCTCTTCTT GAAACAGTGG AGCATCATAC AGAGTTTACT TGTGGTTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Peroxisomal abnormalities in the immortalized human hepatocyte (IHH) cell line.
Histochemistry and cell biology147(4)537-541(2017 Apr)
Klouwer FC,Koster J,Ferdinandusse S,Waterham HR

Revisiting the intraperoxisomal pathway of mammalian PEX7.
Scientific reports511806(2015 Jul)
Rodrigues TA,Grou CP,Azevedo JE

Rhizomelic Chondrodysplasia Punctata Type 1 Caused by a Novel Mutation in the PEX7 Gene.
Journal of clinical research in pediatric endocrinology7(1)69-72(2015 Mar)
?im A,Co?kun S,G?r?kmez O,Y?ksel H,Uluca ?,Pietro ED,Plourde F,Braverman NE

Mechanistic insights into PTS2-mediated peroxisomal protein import: the co-receptor PEX5L drastically increases the interaction strength between the cargo protein and the receptor PEX7.
The Journal of biological chemistry290(8)4928-40(2015 Feb)
Kunze M,Malkani N,Maurer-Stroh S,Wiesinger C,Schmid JA,Berger J

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PEX7 cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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