NEFL cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NEFL
Entrez Gene ID	4747
Full Name	neurofilament light
Synonyms	CMT1F,CMT2E,NF-L,NF68,NFL,PPP1R110
General protein information	Preferred Names neurofilament light Names neurofilament light polypeptide light molecular weight neurofilament protein neurofilament protein, light chain neurofilament subunit NF-L neurofilament triplet L protein neurofilament, light polypeptide 68kDa protein phosphatase 1, regulatory subunit 110
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8p21.2
Summary	Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008].
Disorder MIM:	162280
Disorder Html:	Charcot-Marie-Tooth disease, type 2E, 607684 (3); Charcot-Marie-Tooth disease, type 1F, 607734 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_006158.4	NP_006149.2	neurofilament light polypeptide
NM_006158.5	NP_006149.2	neurofilament light polypeptide

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	NEFL	XP_519665.2
Xenopus tropicalis (tropical clawed frog)	nefl	XP_002932628.2
Canis lupus familiaris (dog)	NEFL	XP_003639928.1
Bos taurus (cattle)	NEFL	NP_776546.1
Rattus norvegicus (Norway rat)	Nefl	NP_113971.1
Danio rerio (zebrafish)	nefla	XP_001333768.2
Homo sapiens (human)	NEFL	NP_006149.2
Danio rerio (zebrafish)	neflb	NP_001034927.1
Gallus gallus (chicken)	NEFL	XP_001232615.1
	NEFL	XP_001107100.1
Mus musculus (house mouse)	Nefl	NP_035040.1

Gene Ontology
Bibliography

Related articles in PubMed

Remyelination modulators in multiple sclerosis patients.
Al-Temaimi R, AbuBaker J, Al-Khairi I, Alroughani R
Experimental and molecular pathology103(3)237-241(2017 12)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We conclude that low BDNF and high LCN2 and NF-L levels are associated with Multiple Sclerosis (MS) pathogenesis, and high IGFBP1level is a biomarker for female MS only, suggesting different MS progression pathways between the sexes. LCN2 is a candidate predictor of response to natalizumab treatment, and NF-L is a candidate predictor of clinically isolated syndrome's (CIS) conversion into MS.
Title: Remyelination modulators in multiple sclerosis patients.

This study showed tat Serum NfL concentration is increased in familial Alzheimer disease prior to symptom onset and correlates with measures of disease stage and severity. Serum NfL may thus be a feasible biomarker of early AD-related neurodegeneration.
Title: Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration.

Results provide evidence that in particular pNfH can be used as a good diagnostic biomarker of ALS at the diagnostic stage. Moreover, results indicate that NfL may be useful in monitoring disease progression in a subset of patients.
Title: Neurofilament markers for ALS correlate with extent of upper and lower motor neuron disease.

Results from 2 independent prospective cohort studies show that serum NFL is a sensitive and dynamic biomarker for axonal injury in concussive traumatic brain injury. The marker should be useful to detect and monitor CNS injury in concussion
Title: Serum neurofilament light as a biomarker for mild traumatic brain injury in contact sports.

Findings support the potential value of serum NfL as a marker of neuroaxonal injury in early multiple sclerosis. Its reduction over time could represent regression to the mean, or a possible treatment effect of IFN-beta-1a. Association with whole brain atrophy and formation of acute white matter lesions has implications to use serum NfL as a biomarker of the overall consequences of brain damage and ongoing disease acti...
Title: Serum neurofilament is associated with progression of brain atrophy and disability in early MS.

The following NEFL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NEFL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28006	NM_006158.5 Latest version!	Homo sapiens neurofilament light (NEFL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu28006	NM_006158.4	Homo sapiens neurofilament light (NEFL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NEFL ( NM_006158.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006149.2 Homo sapiens neurofilament light (NEFL), mRNA.

Price & Availability↑

CloneID	OHu28006
Clone ID Related Accession (Same CDS sequence)	NM_006158.4 , NM_006158.5
Accession Version	NM_006158.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	neurofilament light polypeptide
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC107373.4, BC039237.1, AK225975.1, BC037803.2 and BQ720008.1. This sequence is a reference standard in the RefSeqGene project. On Dec 4, 2012 this sequence version replaced NM_006158.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.75985.1, SRR1803617.69252.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2145774 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGTTCCT TCAGCTACGA GCCGTACTAC TCGACCTCCT ACAAGCGGCG CTACGTGGAG 
ACGCCCCGGG TGCACATCTC CAGCGTGCGC AGCGGCTACA GCACCGCACG CTCAGCTTAC 
TCCAGCTACT CGGCGCCGGT GTCTTCCTCG CTGTCCGTGC GCCGCAGCTA CTCCTCCAGC 
TCTGGATCGT TGATGCCCAG TCTGGAGAAC CTCGACCTGA GCCAGGTAGC CGCCATCAGC 
AACGACCTCA AGTCCATCCG CACGCAGGAG AAGGCGCAGC TCCAGGACCT CAATGACCGC 
TTCGCCAGCT TCATCGAGCG CGTGCACGAG CTGGAGCAGC AGAACAAGGT CCTGGAAGCC 
GAGCTGCTGG TGCTGCGCCA GAAGCACTCC GAGCCATCCC GCTTCCGGGC GCTGTACGAG 
CAGGAGATCC GCGACCTGCG CCTGGCGGCG GAAGATGCCA CCAACGAGAA GCAGGCGCTC 
CAGGGCGAGC GCGAAGGGCT GGAGGAGACC CTGCGCAACC TGCAGGCGCG CTATGAAGAG 
GAGGTGCTGA GCCGCGAGGA CGCCGAGGGC CGGCTGATGG AAGCGCGCAA AGGCGCCGAC 
GAGGCGGCGC TCGCTCGCGC CGAGCTCGAG AAGCGCATCG ACAGCTTGAT GGACGAAATC 
TCTTTTCTGA AGAAAGTGCA CGAAGAGGAG ATCGCCGAAC TGCAGGCGCA GATCCAGTAC 
GCGCAGATCT CCGTGGAGAT GGACGTGACC AAGCCCGACC TTTCCGCCGC GCTCAAGGAC 
ATCCGCGCGC AGTACGAGAA GCTGGCCGCC AAGAACATGC AGAACGCTGA GGAATGGTTC 
AAGAGCCGCT TCACCGTGCT GACCGAGAGC GCCGCCAAGA ACACCGACGC CGTGCGCGCC 
GCCAAGGACG AGGTGTCCGA GAGCCGTCGT CTGCTCAAGG CCAAGACCCT GGAAATCGAA 
GCATGCCGGG GCATGAATGA AGCGCTGGAG AAGCAGCTGC AGGAGCTGGA GGACAAGCAG 
AACGCCGACA TCAGCGCTAT GCAGGACACG ATCAACAAAT TAGAAAATGA ATTGAGGACC 
ACAAAGAGTG AAATGGCACG ATACCTAAAA GAATACCAAG ACCTCCTCAA CGTGAAGATG 
GCTTTGGATA TTGAGATTGC AGCTTACAGG AAACTCTTGG AAGGCGAGGA GACCCGACTC 
AGTTTCACCA GCGTGGGAAG CATAACCAGT GGCTACTCCC AGAGCTCCCA GGTCTTTGGC 
CGATCTGCCT ACGGCGGTTT ACAGACCAGC TCCTATCTGA TGTCCACCCG CTCCTTCCCG 
TCCTACTACA CCAGCCATGT CCAAGAGGAG CAGATCGAAG TGGAGGAAAC CATTGAGGCT 
GCCAAGGCTG AGGAAGCCAA GGATGAGCCC CCCTCTGAAG GAGAAGCCGA GGAGGAGGAG 
AAGGACAAGG AAGAGGCCGA GGAAGAGGAG GCAGCTGAAG AGGAAGAAGC TGCCAAGGAA 
GAGTCTGAAG AAGCAAAAGA AGAAGAAGAA GGAGGTGAAG GTGAAGAAGG AGAGGAAACC 
AAAGAAGCTG AAGAGGAGGA GAAGAAAGTT GAAGGTGCTG GGGAGGAACA AGCAGCTAAG 
AAGAAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006149.2
CDS	355..1986
Translation	MSSFSYEPYYSTSYKRRYVETPRVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENLDLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEISFLKKVHEEEIAELQAQIQYAQISVEMDVTKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFGRSAYGGLQTSSYLMSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEEEKKVEGAGEEQAAKKKD

Target ORF information:

RefSeq Version	NM_006158.4
Organism	Homo sapiens(human)
Definition	Homo sapiens neurofilament light (NEFL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006158.4

ORF Insert Sequence:

ATGAGTTCCT TCAGCTACGA GCCGTACTAC TCGACCTCCT ACAAGCGGCG CTACGTGGAG 
ACGCCCCGGG TGCACATCTC CAGCGTGCGC AGCGGCTACA GCACCGCACG CTCAGCTTAC 
TCCAGCTACT CGGCGCCGGT GTCTTCCTCG CTGTCCGTGC GCCGCAGCTA CTCCTCCAGC 
TCTGGATCGT TGATGCCCAG TCTGGAGAAC CTCGACCTGA GCCAGGTAGC CGCCATCAGC 
AACGACCTCA AGTCCATCCG CACGCAGGAG AAGGCGCAGC TCCAGGACCT CAATGACCGC 
TTCGCCAGCT TCATCGAGCG CGTGCACGAG CTGGAGCAGC AGAACAAGGT CCTGGAAGCC 
GAGCTGCTGG TGCTGCGCCA GAAGCACTCC GAGCCATCCC GCTTCCGGGC GCTGTACGAG 
CAGGAGATCC GCGACCTGCG CCTGGCGGCG GAAGATGCCA CCAACGAGAA GCAGGCGCTC 
CAGGGCGAGC GCGAAGGGCT GGAGGAGACC CTGCGCAACC TGCAGGCGCG CTATGAAGAG 
GAGGTGCTGA GCCGCGAGGA CGCCGAGGGC CGGCTGATGG AAGCGCGCAA AGGCGCCGAC 
GAGGCGGCGC TCGCTCGCGC CGAGCTCGAG AAGCGCATCG ACAGCTTGAT GGACGAAATC 
TCTTTTCTGA AGAAAGTGCA CGAAGAGGAG ATCGCCGAAC TGCAGGCGCA GATCCAGTAC 
GCGCAGATCT CCGTGGAGAT GGACGTGACC AAGCCCGACC TTTCCGCCGC GCTCAAGGAC 
ATCCGCGCGC AGTACGAGAA GCTGGCCGCC AAGAACATGC AGAACGCTGA GGAATGGTTC 
AAGAGCCGCT TCACCGTGCT GACCGAGAGC GCCGCCAAGA ACACCGACGC CGTGCGCGCC 
GCCAAGGACG AGGTGTCCGA GAGCCGTCGT CTGCTCAAGG CCAAGACCCT GGAAATCGAA 
GCATGCCGGG GCATGAATGA AGCGCTGGAG AAGCAGCTGC AGGAGCTGGA GGACAAGCAG 
AACGCCGACA TCAGCGCTAT GCAGGACACG ATCAACAAAT TAGAAAATGA ATTGAGGACC 
ACAAAGAGTG AAATGGCACG ATACCTAAAA GAATACCAAG ACCTCCTCAA CGTGAAGATG 
GCTTTGGATA TTGAGATTGC AGCTTACAGG AAACTCTTGG AAGGCGAGGA GACCCGACTC 
AGTTTCACCA GCGTGGGAAG CATAACCAGT GGCTACTCCC AGAGCTCCCA GGTCTTTGGC 
CGATCTGCCT ACGGCGGTTT ACAGACCAGC TCCTATCTGA TGTCCACCCG CTCCTTCCCG 
TCCTACTACA CCAGCCATGT CCAAGAGGAG CAGATCGAAG TGGAGGAAAC CATTGAGGCT 
GCCAAGGCTG AGGAAGCCAA GGATGAGCCC CCCTCTGAAG GAGAAGCCGA GGAGGAGGAG 
AAGGACAAGG AAGAGGCCGA GGAAGAGGAG GCAGCTGAAG AGGAAGAAGC TGCCAAGGAA 
GAGTCTGAAG AAGCAAAAGA AGAAGAAGAA GGAGGTGAAG GTGAAGAAGG AGAGGAAACC 
AAAGAAGCTG AAGAGGAGGA GAAGAAAGTT GAAGGTGCTG GGGAGGAACA AGCAGCTAAG 
AAGAAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NEFL ( NM_006158.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_006149.2 Homo sapiens neurofilament light (NEFL), mRNA.

Price & Availability↑

CloneID	OHu28006
Clone ID Related Accession (Same CDS sequence)	NM_006158.4 , NM_006158.5
Accession Version	NM_006158.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1632bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	neurofilament light polypeptide
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC039237.1, AK225975.1, BC037803.2 and BQ720008.1. On Dec 4, 2019 this sequence version replaced NM_006158.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK075003.1, BC039237.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGTTCCT TCAGCTACGA GCCGTACTAC TCGACCTCCT ACAAGCGGCG CTACGTGGAG 
ACGCCCCGGG TGCACATCTC CAGCGTGCGC AGCGGCTACA GCACCGCACG CTCAGCTTAC 
TCCAGCTACT CGGCGCCGGT GTCTTCCTCG CTGTCCGTGC GCCGCAGCTA CTCCTCCAGC 
TCTGGATCGT TGATGCCCAG TCTGGAGAAC CTCGACCTGA GCCAGGTAGC CGCCATCAGC 
AACGACCTCA AGTCCATCCG CACGCAGGAG AAGGCGCAGC TCCAGGACCT CAATGACCGC 
TTCGCCAGCT TCATCGAGCG CGTGCACGAG CTGGAGCAGC AGAACAAGGT CCTGGAAGCC 
GAGCTGCTGG TGCTGCGCCA GAAGCACTCC GAGCCATCCC GCTTCCGGGC GCTGTACGAG 
CAGGAGATCC GCGACCTGCG CCTGGCGGCG GAAGATGCCA CCAACGAGAA GCAGGCGCTC 
CAGGGCGAGC GCGAAGGGCT GGAGGAGACC CTGCGCAACC TGCAGGCGCG CTATGAAGAG 
GAGGTGCTGA GCCGCGAGGA CGCCGAGGGC CGGCTGATGG AAGCGCGCAA AGGCGCCGAC 
GAGGCGGCGC TCGCTCGCGC CGAGCTCGAG AAGCGCATCG ACAGCTTGAT GGACGAAATC 
TCTTTTCTGA AGAAAGTGCA CGAAGAGGAG ATCGCCGAAC TGCAGGCGCA GATCCAGTAC 
GCGCAGATCT CCGTGGAGAT GGACGTGACC AAGCCCGACC TTTCCGCCGC GCTCAAGGAC 
ATCCGCGCGC AGTACGAGAA GCTGGCCGCC AAGAACATGC AGAACGCTGA GGAATGGTTC 
AAGAGCCGCT TCACCGTGCT GACCGAGAGC GCCGCCAAGA ACACCGACGC CGTGCGCGCC 
GCCAAGGACG AGGTGTCCGA GAGCCGTCGT CTGCTCAAGG CCAAGACCCT GGAAATCGAA 
GCATGCCGGG GCATGAATGA AGCGCTGGAG AAGCAGCTGC AGGAGCTGGA GGACAAGCAG 
AACGCCGACA TCAGCGCTAT GCAGGACACG ATCAACAAAT TAGAAAATGA ATTGAGGACC 
ACAAAGAGTG AAATGGCACG ATACCTAAAA GAATACCAAG ACCTCCTCAA CGTGAAGATG 
GCTTTGGATA TTGAGATTGC AGCTTACAGG AAACTCTTGG AAGGCGAGGA GACCCGACTC 
AGTTTCACCA GCGTGGGAAG CATAACCAGT GGCTACTCCC AGAGCTCCCA GGTCTTTGGC 
CGATCTGCCT ACGGCGGTTT ACAGACCAGC TCCTATCTGA TGTCCACCCG CTCCTTCCCG 
TCCTACTACA CCAGCCATGT CCAAGAGGAG CAGATCGAAG TGGAGGAAAC CATTGAGGCT 
GCCAAGGCTG AGGAAGCCAA GGATGAGCCC CCCTCTGAAG GAGAAGCCGA GGAGGAGGAG 
AAGGACAAGG AAGAGGCCGA GGAAGAGGAG GCAGCTGAAG AGGAAGAAGC TGCCAAGGAA 
GAGTCTGAAG AAGCAAAAGA AGAAGAAGAA GGAGGTGAAG GTGAAGAAGG AGAGGAAACC 
AAAGAAGCTG AAGAGGAGGA GAAGAAAGTT GAAGGTGCTG GGGAGGAACA AGCAGCTAAG 
AAGAAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006149.2
CDS	98..1729
Translation	MSSFSYEPYYSTSYKRRYVETPRVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENLDLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEISFLKKVHEEEIAELQAQIQYAQISVEMDVTKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFGRSAYGGLQTSSYLMSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEEEKKVEGAGEEQAAKKKD

Target ORF information:

RefSeq Version	NM_006158.5
Organism	Homo sapiens(human)
Definition	Homo sapiens neurofilament light (NEFL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006158.5

ORF Insert Sequence:

ATGAGTTCCT TCAGCTACGA GCCGTACTAC TCGACCTCCT ACAAGCGGCG CTACGTGGAG 
ACGCCCCGGG TGCACATCTC CAGCGTGCGC AGCGGCTACA GCACCGCACG CTCAGCTTAC 
TCCAGCTACT CGGCGCCGGT GTCTTCCTCG CTGTCCGTGC GCCGCAGCTA CTCCTCCAGC 
TCTGGATCGT TGATGCCCAG TCTGGAGAAC CTCGACCTGA GCCAGGTAGC CGCCATCAGC 
AACGACCTCA AGTCCATCCG CACGCAGGAG AAGGCGCAGC TCCAGGACCT CAATGACCGC 
TTCGCCAGCT TCATCGAGCG CGTGCACGAG CTGGAGCAGC AGAACAAGGT CCTGGAAGCC 
GAGCTGCTGG TGCTGCGCCA GAAGCACTCC GAGCCATCCC GCTTCCGGGC GCTGTACGAG 
CAGGAGATCC GCGACCTGCG CCTGGCGGCG GAAGATGCCA CCAACGAGAA GCAGGCGCTC 
CAGGGCGAGC GCGAAGGGCT GGAGGAGACC CTGCGCAACC TGCAGGCGCG CTATGAAGAG 
GAGGTGCTGA GCCGCGAGGA CGCCGAGGGC CGGCTGATGG AAGCGCGCAA AGGCGCCGAC 
GAGGCGGCGC TCGCTCGCGC CGAGCTCGAG AAGCGCATCG ACAGCTTGAT GGACGAAATC 
TCTTTTCTGA AGAAAGTGCA CGAAGAGGAG ATCGCCGAAC TGCAGGCGCA GATCCAGTAC 
GCGCAGATCT CCGTGGAGAT GGACGTGACC AAGCCCGACC TTTCCGCCGC GCTCAAGGAC 
ATCCGCGCGC AGTACGAGAA GCTGGCCGCC AAGAACATGC AGAACGCTGA GGAATGGTTC 
AAGAGCCGCT TCACCGTGCT GACCGAGAGC GCCGCCAAGA ACACCGACGC CGTGCGCGCC 
GCCAAGGACG AGGTGTCCGA GAGCCGTCGT CTGCTCAAGG CCAAGACCCT GGAAATCGAA 
GCATGCCGGG GCATGAATGA AGCGCTGGAG AAGCAGCTGC AGGAGCTGGA GGACAAGCAG 
AACGCCGACA TCAGCGCTAT GCAGGACACG ATCAACAAAT TAGAAAATGA ATTGAGGACC 
ACAAAGAGTG AAATGGCACG ATACCTAAAA GAATACCAAG ACCTCCTCAA CGTGAAGATG 
GCTTTGGATA TTGAGATTGC AGCTTACAGG AAACTCTTGG AAGGCGAGGA GACCCGACTC 
AGTTTCACCA GCGTGGGAAG CATAACCAGT GGCTACTCCC AGAGCTCCCA GGTCTTTGGC 
CGATCTGCCT ACGGCGGTTT ACAGACCAGC TCCTATCTGA TGTCCACCCG CTCCTTCCCG 
TCCTACTACA CCAGCCATGT CCAAGAGGAG CAGATCGAAG TGGAGGAAAC CATTGAGGCT 
GCCAAGGCTG AGGAAGCCAA GGATGAGCCC CCCTCTGAAG GAGAAGCCGA GGAGGAGGAG 
AAGGACAAGG AAGAGGCCGA GGAAGAGGAG GCAGCTGAAG AGGAAGAAGC TGCCAAGGAA 
GAGTCTGAAG AAGCAAAAGA AGAAGAAGAA GGAGGTGAAG GTGAAGAAGG AGAGGAAACC 
AAAGAAGCTG AAGAGGAGGA GAAGAAAGTT GAAGGTGCTG GGGAGGAACA AGCAGCTAAG 
AAGAAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Remyelination modulators in multiple sclerosis patients.
Experimental and molecular pathology103(3)237-241(2017 12)
Al-Temaimi R,AbuBaker J,Al-Khairi I,Alroughani R

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NEFL cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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