Nefl cDNA ORF clone, Rattus norvegicus(Norway rat)

Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP/PPM1F) interacts with neurofilament L and inhibits its?filament association.
Ozaki H, Katoh T, Nakagawa R, Ishihara Y, Sueyoshi N, Kameshita I, Taniguchi T, Hirano T, Yamazaki T, Ishida A
Biochemical and biophysical research communications477(4)820-825(2016 09)

Neurofilament subunits are integral components of synapses and modulate neurotransmission and behavior in vivo.
Yuan A, Sershen H, Veeranna, Basavarajappa BS, Kumar A, Hashim A, Berg M, Lee JH, Sato Y, Rao MV, Mohan PS, Dyakin V, Julien JP, Lee VM, Nixon RA
Molecular psychiatry20(8)986-94(2015 Aug)

CSF neurofilament light chain reflects corticospinal tract degeneration in ALS.
Menke RA, Gray E, Lu CH, Kuhle J, Talbot K, Malaspina A, Turner MR
Annals of clinical and translational neurology2(7)748-55(2015 Jul)

Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction.
Roche SL, Sherman DL, Dissanayake K, Soucy G, Desmazieres A, Lamont DJ, Peles E, Julien JP, Wishart TM, Ribchester RR, Brophy PJ, Gillingwater TH
The Journal of neuroscience : the official journal of the Society for Neuroscience34(38)12904-18(2014 Sep)

Oxidative modification of neurofilament-L and neuronal cell death induced by the catechol neurotoxin, tetrahydropapaveroline.
Kyeong IG, Eum WS, Choi SY, Kang JH
Toxicology letters217(1)59-66(2013 Feb)

Furthermore, the effect of CaMKP on self-assembly of NFL was examined. Electron microscopy revealed that CaMKP markedly prevented NFL from forming large filamentous aggregates, suggesting that CaMKP-binding to NFL inhibits its filament association. These findings may provide new insights into a novel mechanism for regulating network formation of neurofilaments during neuronal differentiation.
Title: Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP/PPM1F) interacts with neurofilament L and inhibits its?filament association.

Data suggest that tetrahydropapaveroline (an endogenous catechol) causes oxidative stress resulting in astrocyte/neuronal cell death via generation of reactive oxygen species and modification/aggregation of NF-L (as in neurodegenerative diseases).
Title: Oxidative modification of neurofilament-L and neuronal cell death induced by the catechol neurotoxin, tetrahydropapaveroline.

LANP directly regulates expression of the neurofilament light chain, an important neuron-specific cytoskeletal gene, by binding to the promoter of this gene and modulating histone acetylation levels
Title: Neuronal differentiation is regulated by leucine-rich acidic nuclear protein (LANP), a member of the inhibitor of histone acetyltransferase complex.

Data show that as a consequence of RhoA knockdown, the process which expresses neurofilament is markedly induced in C12 cells.
Title: Marked effect of RhoA-specific shRNA-producing plasmids on neurite growth in PC12 cells.

Rat pituitary cells from the proopiomelanocortin lineage nearly completely lack NF68 immunoreactivity.
Title: Cells of proopiomelanocortin lineage from the rodent anterior pituitary lack sexually dimorphic expression of neurofilaments.