MYT1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MYT1
Entrez Gene ID	4661
Full Name	myelin transcription factor 1
Synonyms	C20orf36,MTF1,MYTI,NZF2,PLPB1,ZC2H2C1,ZC2HC4A
General protein information	Preferred Names myelin transcription factor 1 Names myelin transcription factor 1 myelin transcription factor I neural zinc finger transcription factor 2 proteolipid protein binding protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.33
Summary	The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. [provided by RefSeq, Jul 2008].
Disorder MIM:	600379

mRNA and Protein(s)

mRNA	Protein	Name
NM_004535.2	NP_004526.1	myelin transcription factor 1
NM_004535.3	NP_004526.1	myelin transcription factor 1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	myt1a	XP_685050.4
Homo sapiens (human)	MYT1	NP_004526.1
	MYT1	XP_002798092.1
Gallus gallus (chicken)	MYT1	XP_417423.4
Xenopus tropicalis (tropical clawed frog)	LOC100490628	XP_002942428.2
Bos taurus (cattle)	MYT1	NP_001178991.1
Canis lupus familiaris (dog)	MYT1	XP_543112.3
Mus musculus (house mouse)	Myt1	NP_001165086.1
Rattus norvegicus (Norway rat)	Myt1	NP_001102085.1

Gene Ontology
Bibliography

Related articles in PubMed

Analysis of transcriptional activity by the Myt1 and Myt1l transcription factors.
Manukyan A, Kowalczyk I, Melhuish TA, Lemiesz A, Wotton D
Journal of cellular biochemistry(2018 Jan)

A novel de novo mutation in MYT1, the unique OAVS gene identified so far.
Berenguer M, Tingaud-Sequeira A, Colovati M, Melaragno MI, Bragagnolo S, Perez ABA, Arveiler B, Lacombe D, Rooryck C
European journal of human genetics : EJHG25(9)1083-1086(2017 Sep)

The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery.
Chow JP, Poon RY
Oncogene32(40)4778-88(2013 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A novel missense variant affecting function, c.323C>T (p.(Ser108Leu)), was identified in MYT1, in a patient presenting with a severe form of OAVS. MYT1 overexpression downregulated all RA receptors genes in vitro.
Title: A novel de novo mutation in MYT1, the unique OAVS gene identified so far.

although depletion of MYT1 alone did not affect long-term cell growth, it potentiated with DNA damage to inhibit cell growth in clonogenic survival and tumor xenograft models
Title: The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery.

UVA-induced caspase-3 cleavage and DNA fragmentation were suppressed by the knockdown of human Myt1 in skin cancer cells.
Title: c-Jun N-terminal kinase 1 phosphorylates Myt1 to prevent UVA-induced skin cancer.

Observational study of gene-disease association. (HuGE Navigator)
Title: Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study.

These results suggesta potential role for Myt1 in the regeneration of oligodendrocyte lineage cells in response to demyelination.
Title: Myelin transcription factor 1 (Myt1) expression in demyelinated lesions of rodent and human CNS.

The following MYT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MYT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13762	NM_004535.3 Latest version!	Homo sapiens myelin transcription factor 1 (MYT1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
View Old Accession Versions >>
OHu13762	NM_004535.2	Homo sapiens myelin transcription factor 1 (MYT1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$399.50-$559.30 $799.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MYT1 ( NM_004535.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_004526.1 Homo sapiens myelin transcription factor 1 (MYT1), mRNA.

Price & Availability↑

CloneID	OHu13762
Clone ID Related Accession (Same CDS sequence)	NM_004535.2 , NM_004535.3
Accession Version	NM_004535.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3366bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	myelin transcription factor 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB020642.1 and BC053638.1. On Jan 28, 2004 this sequence version replaced NM_004535.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB020642.1, SRR1660807.200069.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437, SAMEA2162841 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCTTAG AAAATGAAGA CAAGCGAGCT CGCACCCGAT CCAAGGCCCT GCGAGGACCC 
CCAGAGACCA CAGCTGCAGA CCTCAGCTGC CCCACCCCAG GATGCACAGG CTCAGGGCAC 
GTCCGGGGCA AGTACTCCAG GCACCGAAGT TTACAGAGCT GCCCCCTGGC CAAGAAGAGG 
AAGCTGGAGG GCGCTGAGGC TGAGCACCTG GTGTCCAAGA GGAAGTCACA CCCCCTGAAG 
CTGGCTCTGG ACGAGGGCTA TGGTGTGGAC AGCGACGGCA GTGAGGACAC TGAGGTGAAG 
GACGCCTCTG TTTCGGATGA ATCGGAAGGA ACTCTGGAGG GGGCCGAGGC TGAGACGTCA 
GGACAGGACG AGATTCATCG CCCCGAGACA GCTGAAGGAA GGAGCCCCGT CAAGTCCCAT 
TTTGGATCCA ACCCCATCGG CAGCGCCACT GCCTCCTCCA AGGGCAGCTA CAGCAGCTAC 
CAGGGAATCA TCGCAACTTC TCTCCTGAAC TTGGGTCAAA TTGCTGAAGA GACCCTGGTG 
GAAGAGGACT TGGGCCAGGC GGCCAAGCCA GGTCCTGGCA TTGTGCACCT GCTTCAGGAG 
GCTGCAGAGG GAGCTGCCAG CGAGGAGGGT GAAAAGGGCC TCTTCATCCA GCCAGAGGAT 
GCCGAGGAGG TCGTCGAAGT CACCACCGAG CGCTCCCAGG ACCTGTGTCC CCAGTCCCTG 
GAGGATGCAG CCAGTGAGGA GTCCAGCAAG CAGAAAGGCA TCCTGAGTCA CGAAGAGGAG 
GACGAGGAGG AGGAGGAGGA GGAAGAGGAG GAGGAGGAGG ATGAAGAAGA GGAAGAGGAA 
GAGGAGGAGG AAGAGGAAGA GGAGGAGGAG GAAGAGGAAG AGGAGGAGGA AGAGGAAGAG 
GAAGAGGAGG AGGAGGAGGC AGCTCCTGAT GTGATCTTTC AGGAAGACAC CTCTCACACC 
TCTGCCCAGA AGGCCCCTGA GCTCCGGGGC CCAGAATCAC CCAGTCCCAA GCCTGAGTAC 
TCTGTTATTG TGGAGGTCCG CTCGGATGAT GACAAGGACG AGGACACCCA CTCCCGGAAG 
TCAACAGTCA CTGACGAGTC GGAGATGCAG GACATGATGA CCCGGGGAAA CCTGGGCCTC 
CTGGAGCAGG CCATCGCCCT GAAGGCTGAA CAGGTGCGCA CAGTCTGCGA GCCGGGCTGC 
CCGCCTGCCG AGCAGAGCCA GCTGGGCCTG GGAGAGCCAG GGAAGGCAGC AAAGCCCCTG 
GACACTGTGC GGAAGAGTTA CTACAGTAAA GATCCTTCAA GAGCTGAGAA GCGTGAGATC 
AAGTGTCCAA CACCAGGCTG TGATGGCACT GGCCACGTTA CCGGGTTGTA CCCTCACCAC 
CGCAGCCTTT CTGGCTGTCC CCACAAGGAT AGGATCCCCC CAGAGATCTT AGCCATGCAT 
GAGAACGTGC TGAAGTGCCC CACTCCTGGC TGCACAGGCC AGGGTCACGT GAACAGCAAC 
CGCAACACGC ACAGAAGTTT GTCTGGGTGT CCCATTGCTG CCGCCGAAAA ATTAGCCAAA 
TCCCATGAGA AGCAGCAGCC GCAGACAGGA GATCCTTCCA AGAGTAGCTC CAATTCCGAT 
CGGATCCTCA GGCCCATGTG CTTCGTGAAG CAGCTCGAGG TCCCTCCATA TGGGAGCTAC 
CGGCCCAACG TGGCCCCCGC CACACCCAGG GCCAACTTGG CCAAGGAGCT GGAGAAGTTC 
TCCAAGGTCA CCTTTGACTA CGCAAGTTTC GATGCTCAGG TTTTTGGCAA ACGCATGCTT 
GCCCCAAAGA TTCAGACCAG CGAAACCTCA CCTAAAGCCT TTCAATGCTT TGACTACTCG 
CAGGACGCCG AGGCTGCACA CATGGCTGCC ACTGCCATCC TGAACCTCTC CACGCGCTGC 
TGGGAGATGC CTGAGAACCT CAGCACGAAG CCACAGGACC TCCCCAGCAA GTCTGTGGAT 
ATCGAGGTAG ACGAAAATGG AACCCTGGAC TTGAGCATGC ACAAACACCG CAAACGAGAA 
AATGCTTTCC CCAGCAGCAG CAGCTGCAGC AGCAGCCCCG GTGTGAAGTC TCCCGACGCC 
TCCCAGCGCC ACAGCAGCAC CAGCGCCCCC AGCAGCTCCA TGACCTCTCC CCAGTCCAGC 
CAGGCCTCCC GCCAGGACGA GTGGGACCGG CCCCTGGACT ACACCAAGCC TAGCCGCCTG 
AGAGAGGAGG AACCTGAGGA GTCAGAGCCA GCAGCCCATT CTTTTGCTTC TTCTGAAGCA 
GATGACCAGG AAGTGTCGGA AGAGAATTTT GAGGAGCGGA AGTATCCGGG GGAAGTCACC 
CTGACCAACT TTAAGCTGAA GTTTCTCTCC AAGGACATAA AGAAGGAGCT GCTCACCTGT 
CCCACCCCTG GCTGTGACGG CAGCGGCCAC ATCACCGGGA ACTACGCCTC CCACCGCAGC 
CTCTCTGGTT GCCCTCTTGC TGACAAGAGC CTCAGAAACC TCATGGCTGC CCACTCTGCT 
GACCTCAAGT GCCCCACGCC CGGCTGTGAC GGCTCTGGCC ACATCACAGG GAACTACGCT 
TCACACCGGA GCTTGTCCGG CTGCCCTCGT GCAAAGAAAA GTGGAGTCAA GGTGGCACCC 
ACCAAGGACG ACAAGGAGGA CCCCGAGCTG ATGAAGTGCC CAGTTCCAGG CTGTGTGGGG 
CTCGGTCACA TCAGCGGGAA ATACGCCTCT CACAGGAGCG CATCCGGCTG CCCACTGGCC 
GCCCGCAGGC AGAAGGAAGG GTCCCTCAAT GGCTCGTCAT TCTCCTGGAA GTCCCTGAAG 
AATGAAGGAC CGACCTGCCC CACCCCGGGC TGTGACGGCT CTGGCCACGC CAATGGGAGT 
TTCCTCACCC ACCGGAGTTT GTCAGGCTGT CCCAGAGCAA CCTTTGCTGG AAAGAAGGGA 
AAACTGTCAG GGGATGAGGT CCTCAGTCCA AAGTTCAAGA CTAGCGACGT GTTGGAGAAT 
GATGAGGAGA TCAAGCAGCT GAACCAGGAG ATCCGAGACC TGAACGAGTC CAACTCGGAG 
ATGGAGGCTG CCATGGTGCA GCTGCAGTCC CAGATCTCCT CCATGGAGAA GAACCTGAAG 
AACATCGAGG AGGAGAACAA GCTCATTGAG GAGCAGAATG AAGCCCTGTT TCTGGAGCTG 
TCCGGCCTGA GCCAGGCCCT CATCCAAAGT CTCGCCAATA TCCGCCTTCC GCACATGGAG 
CCAATATGCG AACAGAATTT CGATGCCTAT GTGAGCACCC TCACCGACAT GTACTCCAAC 
CAGGACCCGG AGAACAAGGA CCTCCTGGAG AGCATCAAGC AGGCTGTGAG GGGCATCCAG 
GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004526.1
CDS	365..3730
Translation	MSLENEDKRARTRSKALRGPPETTAADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKRKLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEPGKAAKPLDTVRKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQPQTGDPSKSSSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQCFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKSVDIEVDENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSFLTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEPICEQNFDAYVSTLTDMYSNQDPENKDLLESIKQAVRGIQV

Target ORF information:

RefSeq Version	NM_004535.2
Organism	Homo sapiens(human)
Definition	Homo sapiens myelin transcription factor 1 (MYT1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004535.2

ORF Insert Sequence:

ATGAGCTTAG AAAATGAAGA CAAGCGAGCT CGCACCCGAT CCAAGGCCCT GCGAGGACCC 
CCAGAGACCA CAGCTGCAGA CCTCAGCTGC CCCACCCCAG GATGCACAGG CTCAGGGCAC 
GTCCGGGGCA AGTACTCCAG GCACCGAAGT TTACAGAGCT GCCCCCTGGC CAAGAAGAGG 
AAGCTGGAGG GCGCTGAGGC TGAGCACCTG GTGTCCAAGA GGAAGTCACA CCCCCTGAAG 
CTGGCTCTGG ACGAGGGCTA TGGTGTGGAC AGCGACGGCA GTGAGGACAC TGAGGTGAAG 
GACGCCTCTG TTTCGGATGA ATCGGAAGGA ACTCTGGAGG GGGCCGAGGC TGAGACGTCA 
GGACAGGACG AGATTCATCG CCCCGAGACA GCTGAAGGAA GGAGCCCCGT CAAGTCCCAT 
TTTGGATCCA ACCCCATCGG CAGCGCCACT GCCTCCTCCA AGGGCAGCTA CAGCAGCTAC 
CAGGGAATCA TCGCAACTTC TCTCCTGAAC TTGGGTCAAA TTGCTGAAGA GACCCTGGTG 
GAAGAGGACT TGGGCCAGGC GGCCAAGCCA GGTCCTGGCA TTGTGCACCT GCTTCAGGAG 
GCTGCAGAGG GAGCTGCCAG CGAGGAGGGT GAAAAGGGCC TCTTCATCCA GCCAGAGGAT 
GCCGAGGAGG TCGTCGAAGT CACCACCGAG CGCTCCCAGG ACCTGTGTCC CCAGTCCCTG 
GAGGATGCAG CCAGTGAGGA GTCCAGCAAG CAGAAAGGCA TCCTGAGTCA CGAAGAGGAG 
GACGAGGAGG AGGAGGAGGA GGAAGAGGAG GAGGAGGAGG ATGAAGAAGA GGAAGAGGAA 
GAGGAGGAGG AAGAGGAAGA GGAGGAGGAG GAAGAGGAAG AGGAGGAGGA AGAGGAAGAG 
GAAGAGGAGG AGGAGGAGGC AGCTCCTGAT GTGATCTTTC AGGAAGACAC CTCTCACACC 
TCTGCCCAGA AGGCCCCTGA GCTCCGGGGC CCAGAATCAC CCAGTCCCAA GCCTGAGTAC 
TCTGTTATTG TGGAGGTCCG CTCGGATGAT GACAAGGACG AGGACACCCA CTCCCGGAAG 
TCAACAGTCA CTGACGAGTC GGAGATGCAG GACATGATGA CCCGGGGAAA CCTGGGCCTC 
CTGGAGCAGG CCATCGCCCT GAAGGCTGAA CAGGTGCGCA CAGTCTGCGA GCCGGGCTGC 
CCGCCTGCCG AGCAGAGCCA GCTGGGCCTG GGAGAGCCAG GGAAGGCAGC AAAGCCCCTG 
GACACTGTGC GGAAGAGTTA CTACAGTAAA GATCCTTCAA GAGCTGAGAA GCGTGAGATC 
AAGTGTCCAA CACCAGGCTG TGATGGCACT GGCCACGTTA CCGGGTTGTA CCCTCACCAC 
CGCAGCCTTT CTGGCTGTCC CCACAAGGAT AGGATCCCCC CAGAGATCTT AGCCATGCAT 
GAGAACGTGC TGAAGTGCCC CACTCCTGGC TGCACAGGCC AGGGTCACGT GAACAGCAAC 
CGCAACACGC ACAGAAGTTT GTCTGGGTGT CCCATTGCTG CCGCCGAAAA ATTAGCCAAA 
TCCCATGAGA AGCAGCAGCC GCAGACAGGA GATCCTTCCA AGAGTAGCTC CAATTCCGAT 
CGGATCCTCA GGCCCATGTG CTTCGTGAAG CAGCTCGAGG TCCCTCCATA TGGGAGCTAC 
CGGCCCAACG TGGCCCCCGC CACACCCAGG GCCAACTTGG CCAAGGAGCT GGAGAAGTTC 
TCCAAGGTCA CCTTTGACTA CGCAAGTTTC GATGCTCAGG TTTTTGGCAA ACGCATGCTT 
GCCCCAAAGA TTCAGACCAG CGAAACCTCA CCTAAAGCCT TTCAATGCTT TGACTACTCG 
CAGGACGCCG AGGCTGCACA CATGGCTGCC ACTGCCATCC TGAACCTCTC CACGCGCTGC 
TGGGAGATGC CTGAGAACCT CAGCACGAAG CCACAGGACC TCCCCAGCAA GTCTGTGGAT 
ATCGAGGTAG ACGAAAATGG AACCCTGGAC TTGAGCATGC ACAAACACCG CAAACGAGAA 
AATGCTTTCC CCAGCAGCAG CAGCTGCAGC AGCAGCCCCG GTGTGAAGTC TCCCGACGCC 
TCCCAGCGCC ACAGCAGCAC CAGCGCCCCC AGCAGCTCCA TGACCTCTCC CCAGTCCAGC 
CAGGCCTCCC GCCAGGACGA GTGGGACCGG CCCCTGGACT ACACCAAGCC TAGCCGCCTG 
AGAGAGGAGG AACCTGAGGA GTCAGAGCCA GCAGCCCATT CTTTTGCTTC TTCTGAAGCA 
GATGACCAGG AAGTGTCGGA AGAGAATTTT GAGGAGCGGA AGTATCCGGG GGAAGTCACC 
CTGACCAACT TTAAGCTGAA GTTTCTCTCC AAGGACATAA AGAAGGAGCT GCTCACCTGT 
CCCACCCCTG GCTGTGACGG CAGCGGCCAC ATCACCGGGA ACTACGCCTC CCACCGCAGC 
CTCTCTGGTT GCCCTCTTGC TGACAAGAGC CTCAGAAACC TCATGGCTGC CCACTCTGCT 
GACCTCAAGT GCCCCACGCC CGGCTGTGAC GGCTCTGGCC ACATCACAGG GAACTACGCT 
TCACACCGGA GCTTGTCCGG CTGCCCTCGT GCAAAGAAAA GTGGAGTCAA GGTGGCACCC 
ACCAAGGACG ACAAGGAGGA CCCCGAGCTG ATGAAGTGCC CAGTTCCAGG CTGTGTGGGG 
CTCGGTCACA TCAGCGGGAA ATACGCCTCT CACAGGAGCG CATCCGGCTG CCCACTGGCC 
GCCCGCAGGC AGAAGGAAGG GTCCCTCAAT GGCTCGTCAT TCTCCTGGAA GTCCCTGAAG 
AATGAAGGAC CGACCTGCCC CACCCCGGGC TGTGACGGCT CTGGCCACGC CAATGGGAGT 
TTCCTCACCC ACCGGAGTTT GTCAGGCTGT CCCAGAGCAA CCTTTGCTGG AAAGAAGGGA 
AAACTGTCAG GGGATGAGGT CCTCAGTCCA AAGTTCAAGA CTAGCGACGT GTTGGAGAAT 
GATGAGGAGA TCAAGCAGCT GAACCAGGAG ATCCGAGACC TGAACGAGTC CAACTCGGAG 
ATGGAGGCTG CCATGGTGCA GCTGCAGTCC CAGATCTCCT CCATGGAGAA GAACCTGAAG 
AACATCGAGG AGGAGAACAA GCTCATTGAG GAGCAGAATG AAGCCCTGTT TCTGGAGCTG 
TCCGGCCTGA GCCAGGCCCT CATCCAAAGT CTCGCCAATA TCCGCCTTCC GCACATGGAG 
CCAATATGCG AACAGAATTT CGATGCCTAT GTGAGCACCC TCACCGACAT GTACTCCAAC 
CAGGACCCGG AGAACAAGGA CCTCCTGGAG AGCATCAAGC AGGCTGTGAG GGGCATCCAG 
GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MYT1 ( NM_004535.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004526.1 Homo sapiens myelin transcription factor 1 (MYT1), mRNA.

Price & Availability↑

CloneID	OHu13762
Clone ID Related Accession (Same CDS sequence)	NM_004535.2 , NM_004535.3
Accession Version	NM_004535.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3366bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	myelin transcription factor 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL121581.41, AB020642.1 and BC053638.1. On Nov 23, 2018 this sequence version replaced NM_004535.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB020642.1, SRR1660807.200069.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437, SAMEA2162841 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000328439.6/ ENSP00000327465.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGCTTAG AAAATGAAGA CAAGCGAGCT CGCACCCGAT CCAAGGCCCT GCGAGGACCC 
CCAGAGACCA CAGCTGCAGA CCTCAGCTGC CCCACCCCAG GATGCACAGG CTCAGGGCAC 
GTCCGGGGCA AGTACTCCAG GCACCGAAGT TTACAGAGCT GCCCCCTGGC CAAGAAGAGG 
AAGCTGGAGG GCGCTGAGGC TGAGCACCTG GTGTCCAAGA GGAAGTCACA CCCCCTGAAG 
CTGGCTCTGG ACGAGGGCTA TGGTGTGGAC AGCGACGGCA GTGAGGACAC TGAGGTGAAG 
GACGCCTCTG TTTCGGATGA ATCGGAAGGA ACTCTGGAGG GGGCCGAGGC TGAGACGTCA 
GGACAGGACG AGATTCATCG CCCCGAGACA GCTGAAGGAA GGAGCCCCGT CAAGTCCCAT 
TTTGGATCCA ACCCCATCGG CAGCGCCACT GCCTCCTCCA AGGGCAGCTA CAGCAGCTAC 
CAGGGAATCA TCGCAACTTC TCTCCTGAAC TTGGGTCAAA TTGCTGAAGA GACCCTGGTG 
GAAGAGGACT TGGGCCAGGC GGCCAAGCCA GGTCCTGGCA TTGTGCACCT GCTTCAGGAG 
GCTGCAGAGG GAGCTGCCAG CGAGGAGGGT GAAAAGGGCC TCTTCATCCA GCCAGAGGAT 
GCCGAGGAGG TCGTCGAAGT CACCACCGAG CGCTCCCAGG ACCTGTGTCC CCAGTCCCTG 
GAGGATGCAG CCAGTGAGGA GTCCAGCAAG CAGAAAGGCA TCCTGAGTCA CGAAGAGGAG 
GACGAGGAGG AGGAGGAGGA GGAAGAGGAG GAGGAGGAGG ATGAAGAAGA GGAAGAGGAA 
GAGGAGGAGG AAGAGGAAGA GGAGGAGGAG GAAGAGGAAG AGGAGGAGGA AGAGGAAGAG 
GAAGAGGAGG AGGAGGAGGC AGCTCCTGAT GTGATCTTTC AGGAAGACAC CTCTCACACC 
TCTGCCCAGA AGGCCCCTGA GCTCCGGGGC CCAGAATCAC CCAGTCCCAA GCCTGAGTAC 
TCTGTTATTG TGGAGGTCCG CTCGGATGAT GACAAGGACG AGGACACCCA CTCCCGGAAG 
TCAACAGTCA CTGACGAGTC GGAGATGCAG GACATGATGA CCCGGGGAAA CCTGGGCCTC 
CTGGAGCAGG CCATCGCCCT GAAGGCTGAA CAGGTGCGCA CAGTCTGCGA GCCGGGCTGC 
CCGCCTGCCG AGCAGAGCCA GCTGGGCCTG GGAGAGCCAG GGAAGGCAGC AAAGCCCCTG 
GACACTGTGC GGAAGAGTTA CTACAGTAAA GATCCTTCAA GAGCTGAGAA GCGTGAGATC 
AAGTGTCCAA CACCAGGCTG TGATGGCACT GGCCACGTTA CCGGGTTGTA CCCTCACCAC 
CGCAGCCTTT CTGGCTGTCC CCACAAGGAT AGGATCCCCC CAGAGATCTT AGCCATGCAT 
GAGAACGTGC TGAAGTGCCC CACTCCTGGC TGCACAGGCC AGGGTCACGT GAACAGCAAC 
CGCAACACGC ACAGAAGTTT GTCTGGGTGT CCCATTGCTG CCGCCGAAAA ATTAGCCAAA 
TCCCATGAGA AGCAGCAGCC GCAGACAGGA GATCCTTCCA AGAGTAGCTC CAATTCCGAT 
CGGATCCTCA GGCCCATGTG CTTCGTGAAG CAGCTCGAGG TCCCTCCATA TGGGAGCTAC 
CGGCCCAACG TGGCCCCCGC CACACCCAGG GCCAACTTGG CCAAGGAGCT GGAGAAGTTC 
TCCAAGGTCA CCTTTGACTA CGCAAGTTTC GATGCTCAGG TTTTTGGCAA ACGCATGCTT 
GCCCCAAAGA TTCAGACCAG CGAAACCTCA CCTAAAGCCT TTCAATGCTT TGACTACTCG 
CAGGACGCCG AGGCTGCACA CATGGCTGCC ACTGCCATCC TGAACCTCTC CACGCGCTGC 
TGGGAGATGC CTGAGAACCT CAGCACGAAG CCACAGGACC TCCCCAGCAA GTCTGTGGAT 
ATCGAGGTAG ACGAAAATGG AACCCTGGAC TTGAGCATGC ACAAACACCG CAAACGAGAA 
AATGCTTTCC CCAGCAGCAG CAGCTGCAGC AGCAGCCCCG GTGTGAAGTC TCCCGACGCC 
TCCCAGCGCC ACAGCAGCAC CAGCGCCCCC AGCAGCTCCA TGACCTCTCC CCAGTCCAGC 
CAGGCCTCCC GCCAGGACGA GTGGGACCGG CCCCTGGACT ACACCAAGCC TAGCCGCCTG 
AGAGAGGAGG AACCTGAGGA GTCAGAGCCA GCAGCCCATT CTTTTGCTTC TTCTGAAGCA 
GATGACCAGG AAGTGTCGGA AGAGAATTTT GAGGAGCGGA AGTATCCGGG GGAAGTCACC 
CTGACCAACT TTAAGCTGAA GTTTCTCTCC AAGGACATAA AGAAGGAGCT GCTCACCTGT 
CCCACCCCTG GCTGTGACGG CAGCGGCCAC ATCACCGGGA ACTACGCCTC CCACCGCAGC 
CTCTCTGGTT GCCCTCTTGC TGACAAGAGC CTCAGAAACC TCATGGCTGC CCACTCTGCT 
GACCTCAAGT GCCCCACGCC CGGCTGTGAC GGCTCTGGCC ACATCACAGG GAACTACGCT 
TCACACCGGA GCTTGTCCGG CTGCCCTCGT GCAAAGAAAA GTGGAGTCAA GGTGGCACCC 
ACCAAGGACG ACAAGGAGGA CCCCGAGCTG ATGAAGTGCC CAGTTCCAGG CTGTGTGGGG 
CTCGGTCACA TCAGCGGGAA ATACGCCTCT CACAGGAGCG CATCCGGCTG CCCACTGGCC 
GCCCGCAGGC AGAAGGAAGG GTCCCTCAAT GGCTCGTCAT TCTCCTGGAA GTCCCTGAAG 
AATGAAGGAC CGACCTGCCC CACCCCGGGC TGTGACGGCT CTGGCCACGC CAATGGGAGT 
TTCCTCACCC ACCGGAGTTT GTCAGGCTGT CCCAGAGCAA CCTTTGCTGG AAAGAAGGGA 
AAACTGTCAG GGGATGAGGT CCTCAGTCCA AAGTTCAAGA CTAGCGACGT GTTGGAGAAT 
GATGAGGAGA TCAAGCAGCT GAACCAGGAG ATCCGAGACC TGAACGAGTC CAACTCGGAG 
ATGGAGGCTG CCATGGTGCA GCTGCAGTCC CAGATCTCCT CCATGGAGAA GAACCTGAAG 
AACATCGAGG AGGAGAACAA GCTCATTGAG GAGCAGAATG AAGCCCTGTT TCTGGAGCTG 
TCCGGCCTGA GCCAGGCCCT CATCCAAAGT CTCGCCAATA TCCGCCTTCC GCACATGGAG 
CCAATATGCG AACAGAATTT CGATGCCTAT GTGAGCACCC TCACCGACAT GTACTCCAAC 
CAGGACCCGG AGAACAAGGA CCTCCTGGAG AGCATCAAGC AGGCTGTGAG GGGCATCCAG 
GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004526.1
CDS	387..3752
Translation	MSLENEDKRARTRSKALRGPPETTAADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKRKLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEPGKAAKPLDTVRKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQPQTGDPSKSSSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQCFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKSVDIEVDENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSFLTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEPICEQNFDAYVSTLTDMYSNQDPENKDLLESIKQAVRGIQV

Target ORF information:

RefSeq Version	NM_004535.3
Organism	Homo sapiens(human)
Definition	Homo sapiens myelin transcription factor 1 (MYT1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004535.3

ORF Insert Sequence:

ATGAGCTTAG AAAATGAAGA CAAGCGAGCT CGCACCCGAT CCAAGGCCCT GCGAGGACCC 
CCAGAGACCA CAGCTGCAGA CCTCAGCTGC CCCACCCCAG GATGCACAGG CTCAGGGCAC 
GTCCGGGGCA AGTACTCCAG GCACCGAAGT TTACAGAGCT GCCCCCTGGC CAAGAAGAGG 
AAGCTGGAGG GCGCTGAGGC TGAGCACCTG GTGTCCAAGA GGAAGTCACA CCCCCTGAAG 
CTGGCTCTGG ACGAGGGCTA TGGTGTGGAC AGCGACGGCA GTGAGGACAC TGAGGTGAAG 
GACGCCTCTG TTTCGGATGA ATCGGAAGGA ACTCTGGAGG GGGCCGAGGC TGAGACGTCA 
GGACAGGACG AGATTCATCG CCCCGAGACA GCTGAAGGAA GGAGCCCCGT CAAGTCCCAT 
TTTGGATCCA ACCCCATCGG CAGCGCCACT GCCTCCTCCA AGGGCAGCTA CAGCAGCTAC 
CAGGGAATCA TCGCAACTTC TCTCCTGAAC TTGGGTCAAA TTGCTGAAGA GACCCTGGTG 
GAAGAGGACT TGGGCCAGGC GGCCAAGCCA GGTCCTGGCA TTGTGCACCT GCTTCAGGAG 
GCTGCAGAGG GAGCTGCCAG CGAGGAGGGT GAAAAGGGCC TCTTCATCCA GCCAGAGGAT 
GCCGAGGAGG TCGTCGAAGT CACCACCGAG CGCTCCCAGG ACCTGTGTCC CCAGTCCCTG 
GAGGATGCAG CCAGTGAGGA GTCCAGCAAG CAGAAAGGCA TCCTGAGTCA CGAAGAGGAG 
GACGAGGAGG AGGAGGAGGA GGAAGAGGAG GAGGAGGAGG ATGAAGAAGA GGAAGAGGAA 
GAGGAGGAGG AAGAGGAAGA GGAGGAGGAG GAAGAGGAAG AGGAGGAGGA AGAGGAAGAG 
GAAGAGGAGG AGGAGGAGGC AGCTCCTGAT GTGATCTTTC AGGAAGACAC CTCTCACACC 
TCTGCCCAGA AGGCCCCTGA GCTCCGGGGC CCAGAATCAC CCAGTCCCAA GCCTGAGTAC 
TCTGTTATTG TGGAGGTCCG CTCGGATGAT GACAAGGACG AGGACACCCA CTCCCGGAAG 
TCAACAGTCA CTGACGAGTC GGAGATGCAG GACATGATGA CCCGGGGAAA CCTGGGCCTC 
CTGGAGCAGG CCATCGCCCT GAAGGCTGAA CAGGTGCGCA CAGTCTGCGA GCCGGGCTGC 
CCGCCTGCCG AGCAGAGCCA GCTGGGCCTG GGAGAGCCAG GGAAGGCAGC AAAGCCCCTG 
GACACTGTGC GGAAGAGTTA CTACAGTAAA GATCCTTCAA GAGCTGAGAA GCGTGAGATC 
AAGTGTCCAA CACCAGGCTG TGATGGCACT GGCCACGTTA CCGGGTTGTA CCCTCACCAC 
CGCAGCCTTT CTGGCTGTCC CCACAAGGAT AGGATCCCCC CAGAGATCTT AGCCATGCAT 
GAGAACGTGC TGAAGTGCCC CACTCCTGGC TGCACAGGCC AGGGTCACGT GAACAGCAAC 
CGCAACACGC ACAGAAGTTT GTCTGGGTGT CCCATTGCTG CCGCCGAAAA ATTAGCCAAA 
TCCCATGAGA AGCAGCAGCC GCAGACAGGA GATCCTTCCA AGAGTAGCTC CAATTCCGAT 
CGGATCCTCA GGCCCATGTG CTTCGTGAAG CAGCTCGAGG TCCCTCCATA TGGGAGCTAC 
CGGCCCAACG TGGCCCCCGC CACACCCAGG GCCAACTTGG CCAAGGAGCT GGAGAAGTTC 
TCCAAGGTCA CCTTTGACTA CGCAAGTTTC GATGCTCAGG TTTTTGGCAA ACGCATGCTT 
GCCCCAAAGA TTCAGACCAG CGAAACCTCA CCTAAAGCCT TTCAATGCTT TGACTACTCG 
CAGGACGCCG AGGCTGCACA CATGGCTGCC ACTGCCATCC TGAACCTCTC CACGCGCTGC 
TGGGAGATGC CTGAGAACCT CAGCACGAAG CCACAGGACC TCCCCAGCAA GTCTGTGGAT 
ATCGAGGTAG ACGAAAATGG AACCCTGGAC TTGAGCATGC ACAAACACCG CAAACGAGAA 
AATGCTTTCC CCAGCAGCAG CAGCTGCAGC AGCAGCCCCG GTGTGAAGTC TCCCGACGCC 
TCCCAGCGCC ACAGCAGCAC CAGCGCCCCC AGCAGCTCCA TGACCTCTCC CCAGTCCAGC 
CAGGCCTCCC GCCAGGACGA GTGGGACCGG CCCCTGGACT ACACCAAGCC TAGCCGCCTG 
AGAGAGGAGG AACCTGAGGA GTCAGAGCCA GCAGCCCATT CTTTTGCTTC TTCTGAAGCA 
GATGACCAGG AAGTGTCGGA AGAGAATTTT GAGGAGCGGA AGTATCCGGG GGAAGTCACC 
CTGACCAACT TTAAGCTGAA GTTTCTCTCC AAGGACATAA AGAAGGAGCT GCTCACCTGT 
CCCACCCCTG GCTGTGACGG CAGCGGCCAC ATCACCGGGA ACTACGCCTC CCACCGCAGC 
CTCTCTGGTT GCCCTCTTGC TGACAAGAGC CTCAGAAACC TCATGGCTGC CCACTCTGCT 
GACCTCAAGT GCCCCACGCC CGGCTGTGAC GGCTCTGGCC ACATCACAGG GAACTACGCT 
TCACACCGGA GCTTGTCCGG CTGCCCTCGT GCAAAGAAAA GTGGAGTCAA GGTGGCACCC 
ACCAAGGACG ACAAGGAGGA CCCCGAGCTG ATGAAGTGCC CAGTTCCAGG CTGTGTGGGG 
CTCGGTCACA TCAGCGGGAA ATACGCCTCT CACAGGAGCG CATCCGGCTG CCCACTGGCC 
GCCCGCAGGC AGAAGGAAGG GTCCCTCAAT GGCTCGTCAT TCTCCTGGAA GTCCCTGAAG 
AATGAAGGAC CGACCTGCCC CACCCCGGGC TGTGACGGCT CTGGCCACGC CAATGGGAGT 
TTCCTCACCC ACCGGAGTTT GTCAGGCTGT CCCAGAGCAA CCTTTGCTGG AAAGAAGGGA 
AAACTGTCAG GGGATGAGGT CCTCAGTCCA AAGTTCAAGA CTAGCGACGT GTTGGAGAAT 
GATGAGGAGA TCAAGCAGCT GAACCAGGAG ATCCGAGACC TGAACGAGTC CAACTCGGAG 
ATGGAGGCTG CCATGGTGCA GCTGCAGTCC CAGATCTCCT CCATGGAGAA GAACCTGAAG 
AACATCGAGG AGGAGAACAA GCTCATTGAG GAGCAGAATG AAGCCCTGTT TCTGGAGCTG 
TCCGGCCTGA GCCAGGCCCT CATCCAAAGT CTCGCCAATA TCCGCCTTCC GCACATGGAG 
CCAATATGCG AACAGAATTT CGATGCCTAT GTGAGCACCC TCACCGACAT GTACTCCAAC 
CAGGACCCGG AGAACAAGGA CCTCCTGGAG AGCATCAAGC AGGCTGTGAG GGGCATCCAG 
GTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Analysis of transcriptional activity by the Myt1 and Myt1l transcription factors.
Journal of cellular biochemistry(2018 Jan)
Manukyan A,Kowalczyk I,Melhuish TA,Lemiesz A,Wotton D

A novel de novo mutation in MYT1, the unique OAVS gene identified so far.
European journal of human genetics : EJHG25(9)1083-1086(2017 Sep)
Berenguer M,Tingaud-Sequeira A,Colovati M,Melaragno MI,Bragagnolo S,Perez ABA,Arveiler B,Lacombe D,Rooryck C

The CDK1 inhibitory kinase MYT1 in DNA damage checkpoint recovery.
Oncogene32(40)4778-88(2013 Oct)
Chow JP,Poon RY

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MYT1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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