SULT1A4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SULT1A4
Entrez Gene ID	445329
Full Name	sulfotransferase family 1A member 4
Synonyms	HAST3,M-PST,ST1A3/ST1A4,ST1A4,TL-PST
General protein information	Preferred Names sulfotransferase family 1A member 4 Names sulfotransferase 1A4 SLX1B-SULT1A4 aryl sulfotransferase 1A3/1A4 catecholamine-sulfating phenol sulfotransferase monoamine-sulfating phenol sulfotransferase placental estrogen sulfotransferase sulfokinase sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase, monoamine-preferring thermolabile phenol sulfotransferase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p11.2
Summary	Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16, this gene and SULT1A3 arose from a segmental duplication. Read-through transcription exists between this gene and the upstream SLX1B (SLX1 structure-specific endonuclease subunit homolog B) gene that encodes a protein containing GIY-YIG domains. [provided by RefSeq, Nov 2010].
Disorder MIM:	615819

mRNA and Protein(s)

mRNA	Protein	Name
NM_001017390.2	NP_001017390.1	sulfotransferase 1A4
NM_001017390.3	NP_001017390.1	sulfotransferase 1A4

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LOC454364	XP_003953044.1
Homo sapiens (human)	SULT1A3	NP_808220.1
Homo sapiens (human)	SULT1A4	NP_001017390.1

Gene Ontology
Bibliography

Related articles in PubMed

Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: role of D1 receptor-N-methyl-D-aspartate receptor coupling.
Sidharthan NP, Minchin RF, Butcher NJ
The Journal of biological chemistry288(48)34364-74(2013 Nov)

Ethanol sulfation by the human cytosolic sulfotransferases: a systematic analysis.
Kurogi K, Davidson G, Mohammed YI, Williams FE, Liu MY, Sakakibara Y, Suiko M, Liu MC
Biological & pharmaceutical bulletin35(12)2180-5(2012)

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.
Brand W, Boersma MG, Bik H, Hoek-van den Hil EF, Vervoort J, Barron D, Meinl W, Glatt H, Williamson G, van Bladeren PJ, Rietjens IM
Drug metabolism and disposition: the biological fate of chemicals38(4)617-25(2010 Apr)

Structural and chemical profiling of the human cytosolic sulfotransferases.
Allali-Hassani A, Pan PW, Dombrovski L, Najmanovich R, Tempel W, Dong A, Loppnau P, Martin F, Thornton J, Thonton J, Edwards AM, Bochkarev A, Plotnikov AN, Vedadi M, Arrowsmith CH
PLoS biology5(5)e97(2007 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SULT1A4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SULT1A4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14121	NM_001017390.3 Latest version!	Homo sapiens sulfotransferase family 1A member 4 (SULT1A4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu14121	NM_001017390.2	Homo sapiens sulfotransferase family 1A member 4 (SULT1A4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SULT1A4 ( NM_001017390.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001017390.1 Homo sapiens sulfotransferase family 1A member 4 (SULT1A4), mRNA.

Price & Availability↑

CloneID	OHu14121
Clone ID Related Accession (Same CDS sequence)	NM_001017390.2 , NM_001017390.3
Accession Version	NM_001017390.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	sulfotransferase 1A4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC133555.3. On Dec 1, 2010 this sequence version replaced NM_001017390.1. Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.416860.1, BC132914.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCTGA TCCAGGACAC CTCCCGCCCG CCACTGGAGT ACGTGAAGGG GGTCCCGCTC 
ATCAAGTACT TTGCAGAGGC ACTGGGGCCC CTGCAGAGCT TCCAAGCCCG ACCTGATGAC 
CTGCTCATCA ACACCTACCC CAAGTCTGGC ACCACCTGGG TGAGCCAGAT ACTGGACATG 
ATCTACCAGG GCGGCGACCT AGAGAAGTGT AACCGGGCTC CCATCTACGT ACGGGTGCCC 
TTCCTTGAGG TCAATGATCC AGGGGAACCC TCAGGGCTGG AGACTCTGAA AGACACACCG 
CCCCCACGGC TCATCAAGTC ACACCTGCCC CTGGCTCTGC TCCCTCAGAC TCTGTTGGAT 
CAGAAGGTCA AGGTGGTCTA TGTTGCCCGA AACCCAAAGG ACGTGGCGGT CTCCTACTAC 
CATTTCCACC GTATGGAAAA GGCGCACCCT GAGCCTGGGA CCTGGGACAG CTTCCTGGAA 
AAGTTCATGG CTGGAGAAGT GTCCTACGGG TCCTGGTACC AGCACGTGCA GGAGTGGTGG 
GAGCTGAGCC GCACCCACCC TGTTCTCTAC CTCTTCTATG AAGACATGAA GGAGAACCCC 
AAAAGGGAGA TTCAAAAGAT CCTGGAGTTT GTGGGGCGCT CCCTGCCAGA GGAGACCATG 
GACTTCATGG TTCAGCACAC GTCGTTCAAG GAGATGAAGA AGAACCCTAT GACCAACTAC 
ACCACCGTCC CCCAGGAGCT CATGGACCAC AGCATCTCCC CCTTCATGAG GAAAGGCATG 
GCTGGGGACT GGAAGACCAC CTTCACCGTG GCGCAGAATG AGCGCTTCGA TGCGGACTAT 
GCGGAGAAGA TGGCAGGCTG CAGCCTCAGC TTCCGCTCTG AGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017390.1
CDS	105..992
Translation	MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL

Target ORF information:

RefSeq Version	NM_001017390.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sulfotransferase family 1A member 4 (SULT1A4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017390.2

ORF Insert Sequence:

ATGGAGCTGA TCCAGGACAC CTCCCGCCCG CCACTGGAGT ACGTGAAGGG GGTCCCGCTC 
ATCAAGTACT TTGCAGAGGC ACTGGGGCCC CTGCAGAGCT TCCAAGCCCG ACCTGATGAC 
CTGCTCATCA ACACCTACCC CAAGTCTGGC ACCACCTGGG TGAGCCAGAT ACTGGACATG 
ATCTACCAGG GCGGCGACCT AGAGAAGTGT AACCGGGCTC CCATCTACGT ACGGGTGCCC 
TTCCTTGAGG TCAATGATCC AGGGGAACCC TCAGGGCTGG AGACTCTGAA AGACACACCG 
CCCCCACGGC TCATCAAGTC ACACCTGCCC CTGGCTCTGC TCCCTCAGAC TCTGTTGGAT 
CAGAAGGTCA AGGTGGTCTA TGTTGCCCGA AACCCAAAGG ACGTGGCGGT CTCCTACTAC 
CATTTCCACC GTATGGAAAA GGCGCACCCT GAGCCTGGGA CCTGGGACAG CTTCCTGGAA 
AAGTTCATGG CTGGAGAAGT GTCCTACGGG TCCTGGTACC AGCACGTGCA GGAGTGGTGG 
GAGCTGAGCC GCACCCACCC TGTTCTCTAC CTCTTCTATG AAGACATGAA GGAGAACCCC 
AAAAGGGAGA TTCAAAAGAT CCTGGAGTTT GTGGGGCGCT CCCTGCCAGA GGAGACCATG 
GACTTCATGG TTCAGCACAC GTCGTTCAAG GAGATGAAGA AGAACCCTAT GACCAACTAC 
ACCACCGTCC CCCAGGAGCT CATGGACCAC AGCATCTCCC CCTTCATGAG GAAAGGCATG 
GCTGGGGACT GGAAGACCAC CTTCACCGTG GCGCAGAATG AGCGCTTCGA TGCGGACTAT 
GCGGAGAAGA TGGCAGGCTG CAGCCTCAGC TTCCGCTCTG AGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SULT1A4 ( NM_001017390.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001017390.1 Homo sapiens sulfotransferase family 1A member 4 (SULT1A4), mRNA.

Price & Availability↑

CloneID	OHu14121
Clone ID Related Accession (Same CDS sequence)	NM_001017390.2 , NM_001017390.3
Accession Version	NM_001017390.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 888bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	sulfotransferase 1A4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC133555.3. On Nov 26, 2019 this sequence version replaced NM_001017390.2. Sequence Note: This RefSeq record was created from genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC132920.1, SRR5189661.115900.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCTGA TCCAGGACAC CTCCCGCCCG CCACTGGAGT ACGTGAAGGG GGTCCCGCTC 
ATCAAGTACT TTGCAGAGGC ACTGGGGCCC CTGCAGAGCT TCCAAGCCCG ACCTGATGAC 
CTGCTCATCA ACACCTACCC CAAGTCTGGC ACCACCTGGG TGAGCCAGAT ACTGGACATG 
ATCTACCAGG GCGGCGACCT AGAGAAGTGT AACCGGGCTC CCATCTACGT ACGGGTGCCC 
TTCCTTGAGG TCAATGATCC AGGGGAACCC TCAGGGCTGG AGACTCTGAA AGACACACCG 
CCCCCACGGC TCATCAAGTC ACACCTGCCC CTGGCTCTGC TCCCTCAGAC TCTGTTGGAT 
CAGAAGGTCA AGGTGGTCTA TGTTGCCCGA AACCCAAAGG ACGTGGCGGT CTCCTACTAC 
CATTTCCACC GTATGGAAAA GGCGCACCCT GAGCCTGGGA CCTGGGACAG CTTCCTGGAA 
AAGTTCATGG CTGGAGAAGT GTCCTACGGG TCCTGGTACC AGCACGTGCA GGAGTGGTGG 
GAGCTGAGCC GCACCCACCC TGTTCTCTAC CTCTTCTATG AAGACATGAA GGAGAACCCC 
AAAAGGGAGA TTCAAAAGAT CCTGGAGTTT GTGGGGCGCT CCCTGCCAGA GGAGACCATG 
GACTTCATGG TTCAGCACAC GTCGTTCAAG GAGATGAAGA AGAACCCTAT GACCAACTAC 
ACCACCGTCC CCCAGGAGCT CATGGACCAC AGCATCTCCC CCTTCATGAG GAAAGGCATG 
GCTGGGGACT GGAAGACCAC CTTCACCGTG GCGCAGAATG AGCGCTTCGA TGCGGACTAT 
GCGGAGAAGA TGGCAGGCTG CAGCCTCAGC TTCCGCTCTG AGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017390.1
CDS	78..965
Translation	MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL

Target ORF information:

RefSeq Version	NM_001017390.3
Organism	Homo sapiens(human)
Definition	Homo sapiens sulfotransferase family 1A member 4 (SULT1A4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017390.3

ORF Insert Sequence:

ATGGAGCTGA TCCAGGACAC CTCCCGCCCG CCACTGGAGT ACGTGAAGGG GGTCCCGCTC 
ATCAAGTACT TTGCAGAGGC ACTGGGGCCC CTGCAGAGCT TCCAAGCCCG ACCTGATGAC 
CTGCTCATCA ACACCTACCC CAAGTCTGGC ACCACCTGGG TGAGCCAGAT ACTGGACATG 
ATCTACCAGG GCGGCGACCT AGAGAAGTGT AACCGGGCTC CCATCTACGT ACGGGTGCCC 
TTCCTTGAGG TCAATGATCC AGGGGAACCC TCAGGGCTGG AGACTCTGAA AGACACACCG 
CCCCCACGGC TCATCAAGTC ACACCTGCCC CTGGCTCTGC TCCCTCAGAC TCTGTTGGAT 
CAGAAGGTCA AGGTGGTCTA TGTTGCCCGA AACCCAAAGG ACGTGGCGGT CTCCTACTAC 
CATTTCCACC GTATGGAAAA GGCGCACCCT GAGCCTGGGA CCTGGGACAG CTTCCTGGAA 
AAGTTCATGG CTGGAGAAGT GTCCTACGGG TCCTGGTACC AGCACGTGCA GGAGTGGTGG 
GAGCTGAGCC GCACCCACCC TGTTCTCTAC CTCTTCTATG AAGACATGAA GGAGAACCCC 
AAAAGGGAGA TTCAAAAGAT CCTGGAGTTT GTGGGGCGCT CCCTGCCAGA GGAGACCATG 
GACTTCATGG TTCAGCACAC GTCGTTCAAG GAGATGAAGA AGAACCCTAT GACCAACTAC 
ACCACCGTCC CCCAGGAGCT CATGGACCAC AGCATCTCCC CCTTCATGAG GAAAGGCATG 
GCTGGGGACT GGAAGACCAC CTTCACCGTG GCGCAGAATG AGCGCTTCGA TGCGGACTAT 
GCGGAGAAGA TGGCAGGCTG CAGCCTCAGC TTCCGCTCTG AGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: role of D1 receptor-N-methyl-D-aspartate receptor coupling.
The Journal of biological chemistry288(48)34364-74(2013 Nov)
Sidharthan NP,Minchin RF,Butcher NJ

Ethanol sulfation by the human cytosolic sulfotransferases: a systematic analysis.
Biological & pharmaceutical bulletin35(12)2180-5(2012)
Kurogi K,Davidson G,Mohammed YI,Williams FE,Liu MY,Sakakibara Y,Suiko M,Liu MC

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.
Drug metabolism and disposition: the biological fate of chemicals38(4)617-25(2010 Apr)
Brand W,Boersma MG,Bik H,Hoek-van den Hil EF,Vervoort J,Barron D,Meinl W,Glatt H,Williamson G,van Bladeren PJ,Rietjens IM

Structural and chemical profiling of the human cytosolic sulfotransferases.
PLoS biology5(5)e97(2007 May)
Allali-Hassani A,Pan PW,Dombrovski L,Najmanovich R,Tempel W,Dong A,Loppnau P,Martin F,Thornton J,Thonton J,Edwards AM,Bochkarev A,Plotnikov AN,Vedadi M,Arrowsmith CH

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SULT1A4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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