OR2B3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OR2B3
Entrez Gene ID	442184
Full Name	olfactory receptor family 2 subfamily B member 3
Synonyms	6M1-1,OR2B3P,OR6-14,OR6-4
General protein information	Preferred Names olfactory receptor family 2 subfamily B member 3 Names putative olfactory receptor 2B3 hs6M1-1 olfactory receptor 6-4 olfactory receptor OR6-14
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p22.1
Summary	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001005226.2	NP_001005226.1	putative olfactory receptor 2B3

Pathways from BioSystems

Homologies

Bos taurus (cattle)	LOC515704	XP_002697471.1
Bos taurus (cattle)	LOC784652	XP_002697484.1
Pan troglodytes (chimpanzee)	LOC471929	XP_003311190.1
	OR2B3	XP_001101697.1
Homo sapiens (human)	OR2B3	NP_001005226.1

Gene Ontology
Bibliography

Related articles in PubMed

Common variation contributes to the genetic architecture of social communication traits.
St Pourcain B, Whitehouse AJ, Ang WQ, Warrington NM, Glessner JT, Wang K, Timpson NJ, Evans DM, Kemp JP, Ring SM, McArdle WL, Golding J, Hakonarson H, Pennell CE, Smith GD
Molecular autism4(1)34(2013 Sep)

High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA
PLoS genetics5(10)e1000696(2009 Oct)

The human olfactory receptor gene family.
Malnic B, Godfrey PA, Buck LB
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)

Complex transcription and splicing of odorant receptor genes.
Volz A, Ehlers A, Younger R, Forbes S, Trowsdale J, Schnorr D, Beck S, Ziegler A
The Journal of biological chemistry278(22)19691-701(2003 May)

DEFOG: a practical scheme for deciphering families of genes.
Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R
Genomics80(3)295-302(2002 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.

The following OR2B3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OR2B3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu14591	NM_001005226.2 Latest version!	Homo sapiens olfactory receptor family 2 subfamily B member 3 (OR2B3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OR2B3 ( NM_001005226.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001005226.1 Homo sapiens olfactory receptor family 2 subfamily B member 3 (OR2B3), mRNA.

Price & Availability↑

CloneID	OHu14591
Clone ID Related Accession (Same CDS sequence)	NM_001005226.2
Accession Version	NM_001005226.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	putative olfactory receptor 2B3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ459873.1 and BC136817.1. On Mar 12, 2009 this sequence version replaced NM_001005226.1. ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377173.4/ ENSP00000366378.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAATTGGG AAAATGAGAG CTCCCCAAAA GAGTTTATAC TACTTGGCTT CTCAGATAGG 
GCTTGGCTAC AAATGCCCCT TTTTGTGGTC CTGTTAATAT CATACACAAT CACCATATTT 
GGCAATGTGT CCATCATGAT GGTGTGCATT CTGGATCCCA AACTTCATAC TCCCATGTAT 
TTCTTTCTCA CTAATCTCTC CATCTTAGAT CTCTGCTATA CCACAACTAC AGTCCCTCAT 
ATGTTGGTAA ATATTGGTTG CAACAAAAAG ACCATCAGCT ATGCTGGCTG TGTGGCCCAC 
CTCATCATCT TCCTGGCCCT AGGTGCTACA GAGTGTCTCC TTCTGGCTGT TATGTCCTTT 
GACAGATATG TGGCTGTTTG CAGACCCCTC CACTATGTAG TCATCATGAA TTATTGGTTC 
TGCCTAAGGA TGGCAGCCTT CTCATGGCTC ATTGGTTTCG GCAACTCAGT GCTGCAGTCT 
TCCTTGACTC TTAACATGCC ACGCTGTGGT CACCAGGAAG TGGACCACTT TTTCTGTGAG 
GTGCCTGCAC TTCTCAAGTT GTCATGTGCT GACACAAAGC CTATTGAGGC TGAGCTCTTC 
TTCTTTAGTG TACTAATTCT TCTAATTCCA GTGACATTGA TCCTCATCTC CTATGGCTTC 
ATAGCTCAAG CAGTATTAAA AATCAGGTCA GCAGAAGGAC GGCAAAAAGC ATTTGGGACA 
TGTGGGTCCC ACATGATTGT GGTGTCCCTC TTTTATGGAA CAGCCATTTA TATGTATCTT 
CAACCACCTT CATCCACCTC TAAGGACTGG GGAAAGATGG TTTCCCTCTT CTATGGAATC 
ATCACATCCA TGTTGAACTC CCTCATCTAC AGCCTTAGAA ATAAAGATAT GAAGGAGGCC 
TTCAAGAGGC TGATGCCAAG AATCTTTTTC TGTAAGAAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005226.1
CDS	66..1007
Translation	MNWENESSPKEFILLGFSDRAWLQMPLFVVLLISYTITIFGNVSIMMVCILDPKLHTPMYFFLTNLSILDLCYTTTTVPHMLVNIGCNKKTISYAGCVAHLIIFLALGATECLLLAVMSFDRYVAVCRPLHYVVIMNYWFCLRMAAFSWLIGFGNSVLQSSLTLNMPRCGHQEVDHFFCEVPALLKLSCADTKPIEAELFFFSVLILLIPVTLILISYGFIAQAVLKIRSAEGRQKAFGTCGSHMIVVSLFYGTAIYMYLQPPSSTSKDWGKMVSLFYGIITSMLNSLIYSLRNKDMKEAFKRLMPRIFFCKK

Target ORF information:

RefSeq Version	NM_001005226.2
Organism	Homo sapiens(human)
Definition	Homo sapiens olfactory receptor family 2 subfamily B member 3 (OR2B3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005226.2

ORF Insert Sequence:

ATGAATTGGG AAAATGAGAG CTCCCCAAAA GAGTTTATAC TACTTGGCTT CTCAGATAGG 
GCTTGGCTAC AAATGCCCCT TTTTGTGGTC CTGTTAATAT CATACACAAT CACCATATTT 
GGCAATGTGT CCATCATGAT GGTGTGCATT CTGGATCCCA AACTTCATAC TCCCATGTAT 
TTCTTTCTCA CTAATCTCTC CATCTTAGAT CTCTGCTATA CCACAACTAC AGTCCCTCAT 
ATGTTGGTAA ATATTGGTTG CAACAAAAAG ACCATCAGCT ATGCTGGCTG TGTGGCCCAC 
CTCATCATCT TCCTGGCCCT AGGTGCTACA GAGTGTCTCC TTCTGGCTGT TATGTCCTTT 
GACAGATATG TGGCTGTTTG CAGACCCCTC CACTATGTAG TCATCATGAA TTATTGGTTC 
TGCCTAAGGA TGGCAGCCTT CTCATGGCTC ATTGGTTTCG GCAACTCAGT GCTGCAGTCT 
TCCTTGACTC TTAACATGCC ACGCTGTGGT CACCAGGAAG TGGACCACTT TTTCTGTGAG 
GTGCCTGCAC TTCTCAAGTT GTCATGTGCT GACACAAAGC CTATTGAGGC TGAGCTCTTC 
TTCTTTAGTG TACTAATTCT TCTAATTCCA GTGACATTGA TCCTCATCTC CTATGGCTTC 
ATAGCTCAAG CAGTATTAAA AATCAGGTCA GCAGAAGGAC GGCAAAAAGC ATTTGGGACA 
TGTGGGTCCC ACATGATTGT GGTGTCCCTC TTTTATGGAA CAGCCATTTA TATGTATCTT 
CAACCACCTT CATCCACCTC TAAGGACTGG GGAAAGATGG TTTCCCTCTT CTATGGAATC 
ATCACATCCA TGTTGAACTC CCTCATCTAC AGCCTTAGAA ATAAAGATAT GAAGGAGGCC 
TTCAAGAGGC TGATGCCAAG AATCTTTTTC TGTAAGAAAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Common variation contributes to the genetic architecture of social communication traits.
Molecular autism4(1)34(2013 Sep)
St Pourcain B,Whitehouse AJ,Ang WQ,Warrington NM,Glessner JT,Wang K,Timpson NJ,Evans DM,Kemp JP,Ring SM,McArdle WL,Golding J,Hakonarson H,Pennell CE,Smith GD

High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.
PLoS genetics5(10)e1000696(2009 Oct)
Barcellos LF,May SL,Ramsay PP,Quach HL,Lane JA,Nititham J,Noble JA,Taylor KE,Quach DL,Chung SA,Kelly JA,Moser KL,Behrens TW,Seldin MF,Thomson G,Harley JB,Gaffney PM,Criswell LA

The human olfactory receptor gene family.
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)
Malnic B,Godfrey PA,Buck LB

Complex transcription and splicing of odorant receptor genes.
The Journal of biological chemistry278(22)19691-701(2003 May)
Volz A,Ehlers A,Younger R,Forbes S,Trowsdale J,Schnorr D,Beck S,Ziegler A

DEFOG: a practical scheme for deciphering families of genes.
Genomics80(3)295-302(2002 Sep)
Fuchs T,Malecova B,Linhart C,Sharan R,Khen M,Herwig R,Shmulevich D,Elkon R,Steinfath M,O'Brien JK,Radelof U,Lehrach H,Lancet D,Shamir R

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OR2B3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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