LHX1 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LHX1
Entrez Gene ID	3975
Full Name	LIM homeobox 1
Synonyms	LIM-1,LIM1
General protein information	Preferred Names LIM homeobox 1 Names LIM/homeobox protein Lhx1 LIM homeobox protein 1 homeobox protein Lim-1
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 17 Map Location: 17q12
Summary	This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for the development of the renal and urogenital systems. This gene is a candidate for Mayer-Rokitansky-Kuster-Hauser syndrome, a disorder characterized by anomalies in the female genital tract. [provided by RefSeq, Dec 2010].
Disorder MIM:	601999

mRNA and Protein(s)

mRNA	Protein	Name
NM_005568.5	NP_005559.2	LIM/homeobox protein Lhx1
NM_005568.4	NP_005559.2	LIM/homeobox protein Lhx1
XM_011546810.1	XP_011545112.1	LIM/homeobox protein Lhx1 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LHX1	NP_001029088.1
Canis lupus familiaris (dog)	LHX1	XP_003639347.1
Bos taurus (cattle)	LHX1	NP_001098917.1
Mus musculus (house mouse)	Lhx1	NP_032524.1
Rattus norvegicus (Norway rat)	Lhx1	NP_665887.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011134	XP_309513.3
Gallus gallus (chicken)	LHX1	NP_990744.1
Danio rerio (zebrafish)	lhx1a	NP_571291.1
Homo sapiens (human)	LHX1	NP_005559.2
Drosophila melanogaster (fruit fly)	Lim1	NP_572505.1
Xenopus tropicalis (tropical clawed frog)	lhx1	NP_001093698.1

Gene Ontology
Bibliography

Related articles in PubMed

Genetic analysis of Mayer-Rokitansky-Kuster-Hauser syndrome in a large cohort of families.
Williams LS, Demir Eksi D, Shen Y, Lossie AC, Chorich LP, Sullivan ME, Phillips JA 3rd, Erman M, Kim HG, Alper OM, Layman LC
Fertility and sterility108(1)145-151.e2(2017 Jul)

Identification and functional analysis of a novel LHX1 mutation associated with congenital absence of the uterus and vagina.
Zhang W, Zhou X, Liu L, Zhu Y, Liu C, Pan H, Xing Q, Wang J, Wang X, Zhang X, Cao Y, Wang B
Oncotarget8(5)8785-8790(2017 Jan)

TBX6, LHX1 and copy number variations in the complex genetics of M?llerian aplasia.
Sandbacka M, Laivuori H, Freitas ?, Halttunen M, Jokimaa V, Morin-Papunen L, Rosenberg C, Aittom?ki K
Orphanet journal of rare diseases8125(2013 Aug)

Functional genomics identifies drivers of medulloblastoma dissemination.
Mumert M, Dubuc A, Wu X, Northcott PA, Chin SS, Pedone CA, Taylor MD, Fults DW
Cancer research72(19)4944-53(2012 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our MRKH families included 43 quads, 26 trios, and 30 duos. Of our MRKH probands, 87/147 (59%) had MRKH type 1 and 60/147 (41%) had type 2 with additional anomalies. CONCLUSION(S): Although the prevalence of WNT4, HNF1B, and LHX1 point mutations is low in people with MRKH, the prevalence of CNVs was approximately 19%.
Title: Genetic analysis of Mayer-Rokitansky-Kuster-Hauser syndrome in a large cohort of families.

Data have identified TBX6 as a new gene associated with Mullerian aplasia. The results also support the relevance of LHX1 and CNVs in the development of this congenital malformation.
Title: TBX6, LHX1 and copy number variations in the complex genetics of M?llerian aplasia.

Data indicate that expression of ERAS, LHX1, and CCRK is increased in aggressive subgroups of medulloblastomas.
Title: Functional genomics identifies drivers of medulloblastoma dissemination.

study concludes that heterozygous mutations of LHX1 might be one cause of the Mayer-Rokitansky-Kuster-Hauser syndrome in a subgroup of patients
Title: Frame shift mutation of LHX1 is associated with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.

Lim1/LIM1 expression in neonatal, adult mouse and human endometrium suggesting Lim1/LIM1 may have a role in endometrial development and remodelling
Title: Lim1/LIM1 is expressed in developing and adult mouse and human endometrium.

The following LHX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LHX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13751	NM_005568.5 Latest version!	Homo sapiens LIM homeobox 1 (LHX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu13751	XM_011546810.1 Latest version!	Homo sapiens LIM homeobox 1 (LHX1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu13751	NM_005568.4	Homo sapiens LIM homeobox 1 (LHX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LHX1 ( NM_005568.5 ) cDNA ORF clone, Homo sapiens(Human) -> NP_005559.2 Homo sapiens LIM homeobox 1 (LHX1), mRNA.

Price & Availability↑

CloneID	OHu13751
Clone ID Related Accession (Same CDS sequence)	NM_005568.5 , NM_005568.4 , XM_011546810.1
Accession Version	NM_005568.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	LIM/homeobox protein Lhx1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC020470.1, BC101674.1 and AC243773.3. On May 17, 2019 this sequence version replaced NM_005568.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR6380201.70499.3, U14755.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145774 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000614239.1/ ENSP00000477829.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTTCACT GTGCCGGCTG CAAAAGGCCC ATCCTGGACC GCTTTCTCTT GAACGTGCTG 
GACAGGGCCT GGCACGTCAA GTGCGTCCAG TGCTGTGAAT GTAAATGCAA CCTGACCGAG 
AAGTGCTTCT CCAGGGAAGG CAAACTCTAC TGCAAGAACG ACTTCTTCCG GTGTTTCGGT 
ACCAAATGCG CAGGCTGCGC TCAGGGCATC TCCCCTAGCG ACCTGGTGCG GAGAGCGCGG 
AGCAAAGTGT TTCACCTGAA CTGCTTCACC TGCATGATGT GTAACAAGCA GCTCTCCACT 
GGCGAGGAAC TCTACATCAT CGACGAGAAT AAGTTCGTCT GCAAAGAGGA TTACCTAAGT 
AACAGCAGTG TTGCCAAAGA GAACAGCCTT CACTCGGCCA CCACGGGCAG TGACCCCAGT 
TTGTCTCCGG ATTCCCAAGA CCCGTCGCAG GACGACGCCA AGGACTCGGA GAGCGCCAAC 
GTGTCGGACA AGGAAGCGGG TAGCAACGAG AATGACGACC AGAACCTGGG CGCCAAGCGG 
CGGGGACCGC GCACCACCAT CAAAGCCAAG CAGCTGGAGA CGCTGAAGGC CGCCTTCGCT 
GCTACACCCA AGCCCACCCG CCACATCCGC GAGCAGCTGG CGCAGGAGAC CGGCCTCAAC 
ATGCGCGTCA TTCAGGTCTG GTTCCAGAAC CGGCGCTCCA AGGAGCGGAG GATGAAGCAG 
CTGAGCGCCC TGGGCGCCCG GCGCCACGCC TTCTTCCGCA GTCCGCGCCG GATGCGGCCG 
CTGGTGGACC GCCTGGAGCC GGGCGAGCTC ATCCCCAATG GTCCCTTCTC CTTCTACGGA 
GATTACCAGA GCGAGTACTA CGGGCCCGGG GGCAACTACG ACTTCTTCCC GCAAGGCCCC 
CCGTCCTCGC AGGCCCAGAC ACCAGTGGAC CTACCCTTCG TGCCGTCATC TGGGCCGTCC 
GGGACGCCCC TGGGTGGCCT GGAGCACCCG CTGCCGGGCC ACCACCCGTC GAGCGAGGCG 
CAGCGGTTTA CCGACATCCT GGCGCACCCA CCCGGGGACT CGCCCAGCCC CGAGCCCAGC 
CTGCCCGGGC CTCTGCACTC CATGTCGGCC GAGGTCTTCG GACCCAGCCC GCCCTTCTCG 
TCGCTGTCGG TCAACGGTGG GGCGAGCTAC GGAAACCACC TGTCCCACCC CCCCGAAATG 
AACGAGGCGG CCGTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005559.2
CDS	724..1944
Translation	MVHCAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQGPPSSQAQTPVDLPFVPSSGPSGTPLGGLEHPLPGHHPSSEAQRFTDILAHPPGDSPSPEPSLPGPLHSMSAEVFGPSPPFSSLSVNGGASYGNHLSHPPEMNEAAVW

Target ORF information:

RefSeq Version	NM_005568.5
Organism	Homo sapiens(human)
Definition	Homo sapiens LIM homeobox 1 (LHX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005568.5

ORF Insert Sequence:

ATGGTTCACT GTGCCGGCTG CAAAAGGCCC ATCCTGGACC GCTTTCTCTT GAACGTGCTG 
GACAGGGCCT GGCACGTCAA GTGCGTCCAG TGCTGTGAAT GTAAATGCAA CCTGACCGAG 
AAGTGCTTCT CCAGGGAAGG CAAACTCTAC TGCAAGAACG ACTTCTTCCG GTGTTTCGGT 
ACCAAATGCG CAGGCTGCGC TCAGGGCATC TCCCCTAGCG ACCTGGTGCG GAGAGCGCGG 
AGCAAAGTGT TTCACCTGAA CTGCTTCACC TGCATGATGT GTAACAAGCA GCTCTCCACT 
GGCGAGGAAC TCTACATCAT CGACGAGAAT AAGTTCGTCT GCAAAGAGGA TTACCTAAGT 
AACAGCAGTG TTGCCAAAGA GAACAGCCTT CACTCGGCCA CCACGGGCAG TGACCCCAGT 
TTGTCTCCGG ATTCCCAAGA CCCGTCGCAG GACGACGCCA AGGACTCGGA GAGCGCCAAC 
GTGTCGGACA AGGAAGCGGG TAGCAACGAG AATGACGACC AGAACCTGGG CGCCAAGCGG 
CGGGGACCGC GCACCACCAT CAAAGCCAAG CAGCTGGAGA CGCTGAAGGC CGCCTTCGCT 
GCTACACCCA AGCCCACCCG CCACATCCGC GAGCAGCTGG CGCAGGAGAC CGGCCTCAAC 
ATGCGCGTCA TTCAGGTCTG GTTCCAGAAC CGGCGCTCCA AGGAGCGGAG GATGAAGCAG 
CTGAGCGCCC TGGGCGCCCG GCGCCACGCC TTCTTCCGCA GTCCGCGCCG GATGCGGCCG 
CTGGTGGACC GCCTGGAGCC GGGCGAGCTC ATCCCCAATG GTCCCTTCTC CTTCTACGGA 
GATTACCAGA GCGAGTACTA CGGGCCCGGG GGCAACTACG ACTTCTTCCC GCAAGGCCCC 
CCGTCCTCGC AGGCCCAGAC ACCAGTGGAC CTACCCTTCG TGCCGTCATC TGGGCCGTCC 
GGGACGCCCC TGGGTGGCCT GGAGCACCCG CTGCCGGGCC ACCACCCGTC GAGCGAGGCG 
CAGCGGTTTA CCGACATCCT GGCGCACCCA CCCGGGGACT CGCCCAGCCC CGAGCCCAGC 
CTGCCCGGGC CTCTGCACTC CATGTCGGCC GAGGTCTTCG GACCCAGCCC GCCCTTCTCG 
TCGCTGTCGG TCAACGGTGG GGCGAGCTAC GGAAACCACC TGTCCCACCC CCCCGAAATG 
AACGAGGCGG CCGTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LHX1 ( NM_005568.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_005559.2 Homo sapiens LIM homeobox 1 (LHX1), mRNA.

Price & Availability↑

CloneID	OHu13751
Clone ID Related Accession (Same CDS sequence)	NM_005568.5 , NM_005568.4 , XM_011546810.1
Accession Version	NM_005568.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	LIM/homeobox protein Lhx1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC020470.1, BC101674.1 and AC243773.3. On Mar 25, 2014 this sequence version replaced NM_005568.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U14755.1, BC101674.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145774 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTTCACT GTGCCGGCTG CAAAAGGCCC ATCCTGGACC GCTTTCTCTT GAACGTGCTG 
GACAGGGCCT GGCACGTCAA GTGCGTCCAG TGCTGTGAAT GTAAATGCAA CCTGACCGAG 
AAGTGCTTCT CCAGGGAAGG CAAACTCTAC TGCAAGAACG ACTTCTTCCG GTGTTTCGGT 
ACCAAATGCG CAGGCTGCGC TCAGGGCATC TCCCCTAGCG ACCTGGTGCG GAGAGCGCGG 
AGCAAAGTGT TTCACCTGAA CTGCTTCACC TGCATGATGT GTAACAAGCA GCTCTCCACT 
GGCGAGGAAC TCTACATCAT CGACGAGAAT AAGTTCGTCT GCAAAGAGGA TTACCTAAGT 
AACAGCAGTG TTGCCAAAGA GAACAGCCTT CACTCGGCCA CCACGGGCAG TGACCCCAGT 
TTGTCTCCGG ATTCCCAAGA CCCGTCGCAG GACGACGCCA AGGACTCGGA GAGCGCCAAC 
GTGTCGGACA AGGAAGCGGG TAGCAACGAG AATGACGACC AGAACCTGGG CGCCAAGCGG 
CGGGGACCGC GCACCACCAT CAAAGCCAAG CAGCTGGAGA CGCTGAAGGC CGCCTTCGCT 
GCTACACCCA AGCCCACCCG CCACATCCGC GAGCAGCTGG CGCAGGAGAC CGGCCTCAAC 
ATGCGCGTCA TTCAGGTCTG GTTCCAGAAC CGGCGCTCCA AGGAGCGGAG GATGAAGCAG 
CTGAGCGCCC TGGGCGCCCG GCGCCACGCC TTCTTCCGCA GTCCGCGCCG GATGCGGCCG 
CTGGTGGACC GCCTGGAGCC GGGCGAGCTC ATCCCCAATG GTCCCTTCTC CTTCTACGGA 
GATTACCAGA GCGAGTACTA CGGGCCCGGG GGCAACTACG ACTTCTTCCC GCAAGGCCCC 
CCGTCCTCGC AGGCCCAGAC ACCAGTGGAC CTACCCTTCG TGCCGTCATC TGGGCCGTCC 
GGGACGCCCC TGGGTGGCCT GGAGCACCCG CTGCCGGGCC ACCACCCGTC GAGCGAGGCG 
CAGCGGTTTA CCGACATCCT GGCGCACCCA CCCGGGGACT CGCCCAGCCC CGAGCCCAGC 
CTGCCCGGGC CTCTGCACTC CATGTCGGCC GAGGTCTTCG GACCCAGCCC GCCCTTCTCG 
TCGCTGTCGG TCAACGGTGG GGCGAGCTAC GGAAACCACC TGTCCCACCC CCCCGAAATG 
AACGAGGCGG CCGTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005559.2
CDS	724..1944
Translation	MVHCAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQGPPSSQAQTPVDLPFVPSSGPSGTPLGGLEHPLPGHHPSSEAQRFTDILAHPPGDSPSPEPSLPGPLHSMSAEVFGPSPPFSSLSVNGGASYGNHLSHPPEMNEAAVW

Target ORF information:

RefSeq Version	NM_005568.4
Organism	Homo sapiens(human)
Definition	Homo sapiens LIM homeobox 1 (LHX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005568.4

ORF Insert Sequence:

ATGGTTCACT GTGCCGGCTG CAAAAGGCCC ATCCTGGACC GCTTTCTCTT GAACGTGCTG 
GACAGGGCCT GGCACGTCAA GTGCGTCCAG TGCTGTGAAT GTAAATGCAA CCTGACCGAG 
AAGTGCTTCT CCAGGGAAGG CAAACTCTAC TGCAAGAACG ACTTCTTCCG GTGTTTCGGT 
ACCAAATGCG CAGGCTGCGC TCAGGGCATC TCCCCTAGCG ACCTGGTGCG GAGAGCGCGG 
AGCAAAGTGT TTCACCTGAA CTGCTTCACC TGCATGATGT GTAACAAGCA GCTCTCCACT 
GGCGAGGAAC TCTACATCAT CGACGAGAAT AAGTTCGTCT GCAAAGAGGA TTACCTAAGT 
AACAGCAGTG TTGCCAAAGA GAACAGCCTT CACTCGGCCA CCACGGGCAG TGACCCCAGT 
TTGTCTCCGG ATTCCCAAGA CCCGTCGCAG GACGACGCCA AGGACTCGGA GAGCGCCAAC 
GTGTCGGACA AGGAAGCGGG TAGCAACGAG AATGACGACC AGAACCTGGG CGCCAAGCGG 
CGGGGACCGC GCACCACCAT CAAAGCCAAG CAGCTGGAGA CGCTGAAGGC CGCCTTCGCT 
GCTACACCCA AGCCCACCCG CCACATCCGC GAGCAGCTGG CGCAGGAGAC CGGCCTCAAC 
ATGCGCGTCA TTCAGGTCTG GTTCCAGAAC CGGCGCTCCA AGGAGCGGAG GATGAAGCAG 
CTGAGCGCCC TGGGCGCCCG GCGCCACGCC TTCTTCCGCA GTCCGCGCCG GATGCGGCCG 
CTGGTGGACC GCCTGGAGCC GGGCGAGCTC ATCCCCAATG GTCCCTTCTC CTTCTACGGA 
GATTACCAGA GCGAGTACTA CGGGCCCGGG GGCAACTACG ACTTCTTCCC GCAAGGCCCC 
CCGTCCTCGC AGGCCCAGAC ACCAGTGGAC CTACCCTTCG TGCCGTCATC TGGGCCGTCC 
GGGACGCCCC TGGGTGGCCT GGAGCACCCG CTGCCGGGCC ACCACCCGTC GAGCGAGGCG 
CAGCGGTTTA CCGACATCCT GGCGCACCCA CCCGGGGACT CGCCCAGCCC CGAGCCCAGC 
CTGCCCGGGC CTCTGCACTC CATGTCGGCC GAGGTCTTCG GACCCAGCCC GCCCTTCTCG 
TCGCTGTCGG TCAACGGTGG GGCGAGCTAC GGAAACCACC TGTCCCACCC CCCCGAAATG 
AACGAGGCGG CCGTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LHX1 ( XM_011546810.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011545112.1 Homo sapiens LIM homeobox 1 (LHX1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu13751
Clone ID Related Accession (Same CDS sequence)	NM_005568.5 , NM_005568.4 , XM_011546810.1
Accession Version	XM_011546810.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1221bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	LIM/homeobox protein Lhx1 isoform X1
Comment

ATGGTTCACT GTGCCGGCTG CAAAAGGCCC ATCCTGGACC GCTTTCTCTT GAACGTGCTG 
GACAGGGCCT GGCACGTCAA GTGCGTCCAG TGCTGTGAAT GTAAATGCAA CCTGACCGAG 
AAGTGCTTCT CCAGGGAAGG CAAACTCTAC TGCAAGAACG ACTTCTTCCG GTGTTTCGGT 
ACCAAATGCG CAGGCTGCGC TCAGGGCATC TCCCCTAGCG ACCTGGTGCG GAGAGCGCGG 
AGCAAAGTGT TTCACCTGAA CTGCTTCACC TGCATGATGT GTAACAAGCA GCTCTCCACT 
GGCGAGGAAC TCTACATCAT CGACGAGAAT AAGTTCGTCT GCAAAGAGGA TTACCTAAGT 
AACAGCAGTG TTGCCAAAGA GAACAGCCTT CACTCGGCCA CCACGGGCAG TGACCCCAGT 
TTGTCTCCGG ATTCCCAAGA CCCGTCGCAG GACGACGCCA AGGACTCGGA GAGCGCCAAC 
GTGTCGGACA AGGAAGCGGG TAGCAACGAG AATGACGACC AGAACCTGGG CGCCAAGCGG 
CGGGGACCGC GCACCACCAT CAAAGCCAAG CAGCTGGAGA CGCTGAAGGC CGCCTTCGCT 
GCTACACCCA AGCCCACCCG CCACATCCGC GAGCAGCTGG CGCAGGAGAC CGGCCTCAAC 
ATGCGCGTCA TTCAGGTCTG GTTCCAGAAC CGGCGCTCCA AGGAGCGGAG GATGAAGCAG 
CTGAGCGCCC TGGGCGCCCG GCGCCACGCC TTCTTCCGCA GTCCGCGCCG GATGCGGCCG 
CTGGTGGACC GCCTGGAGCC GGGCGAGCTC ATCCCCAATG GTCCCTTCTC CTTCTACGGA 
GATTACCAGA GCGAGTACTA CGGGCCCGGG GGCAACTACG ACTTCTTCCC GCAAGGCCCC 
CCGTCCTCGC AGGCCCAGAC ACCAGTGGAC CTACCCTTCG TGCCGTCATC TGGGCCGTCC 
GGGACGCCCC TGGGTGGCCT GGAGCACCCG CTGCCGGGCC ACCACCCGTC GAGCGAGGCG 
CAGCGGTTTA CCGACATCCT GGCGCACCCA CCCGGGGACT CGCCCAGCCC CGAGCCCAGC 
CTGCCCGGGC CTCTGCACTC CATGTCGGCC GAGGTCTTCG GACCCAGCCC GCCCTTCTCG 
TCGCTGTCGG TCAACGGTGG GGCGAGCTAC GGAAACCACC TGTCCCACCC CCCCGAAATG 
AACGAGGCGG CCGTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011545112.1

Translation

MVHCAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQGPPSSQAQTPVDLPFVPSSGPSGTPLGGLEHPLPGHHPSSEAQRFTDILAHPPGDSPSPEPSLPGPLHSMSAEVFGPSPPFSSLSVNGGASYGNHLSHPPEMNEAAVW

Target ORF information:

RefSeq Version	XM_011546810.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens LIM homeobox 1 (LHX1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011546810.1

ORF Insert Sequence:

ATGGTTCACT GTGCCGGCTG CAAAAGGCCC ATCCTGGACC GCTTTCTCTT GAACGTGCTG 
GACAGGGCCT GGCACGTCAA GTGCGTCCAG TGCTGTGAAT GTAAATGCAA CCTGACCGAG 
AAGTGCTTCT CCAGGGAAGG CAAACTCTAC TGCAAGAACG ACTTCTTCCG GTGTTTCGGT 
ACCAAATGCG CAGGCTGCGC TCAGGGCATC TCCCCTAGCG ACCTGGTGCG GAGAGCGCGG 
AGCAAAGTGT TTCACCTGAA CTGCTTCACC TGCATGATGT GTAACAAGCA GCTCTCCACT 
GGCGAGGAAC TCTACATCAT CGACGAGAAT AAGTTCGTCT GCAAAGAGGA TTACCTAAGT 
AACAGCAGTG TTGCCAAAGA GAACAGCCTT CACTCGGCCA CCACGGGCAG TGACCCCAGT 
TTGTCTCCGG ATTCCCAAGA CCCGTCGCAG GACGACGCCA AGGACTCGGA GAGCGCCAAC 
GTGTCGGACA AGGAAGCGGG TAGCAACGAG AATGACGACC AGAACCTGGG CGCCAAGCGG 
CGGGGACCGC GCACCACCAT CAAAGCCAAG CAGCTGGAGA CGCTGAAGGC CGCCTTCGCT 
GCTACACCCA AGCCCACCCG CCACATCCGC GAGCAGCTGG CGCAGGAGAC CGGCCTCAAC 
ATGCGCGTCA TTCAGGTCTG GTTCCAGAAC CGGCGCTCCA AGGAGCGGAG GATGAAGCAG 
CTGAGCGCCC TGGGCGCCCG GCGCCACGCC TTCTTCCGCA GTCCGCGCCG GATGCGGCCG 
CTGGTGGACC GCCTGGAGCC GGGCGAGCTC ATCCCCAATG GTCCCTTCTC CTTCTACGGA 
GATTACCAGA GCGAGTACTA CGGGCCCGGG GGCAACTACG ACTTCTTCCC GCAAGGCCCC 
CCGTCCTCGC AGGCCCAGAC ACCAGTGGAC CTACCCTTCG TGCCGTCATC TGGGCCGTCC 
GGGACGCCCC TGGGTGGCCT GGAGCACCCG CTGCCGGGCC ACCACCCGTC GAGCGAGGCG 
CAGCGGTTTA CCGACATCCT GGCGCACCCA CCCGGGGACT CGCCCAGCCC CGAGCCCAGC 
CTGCCCGGGC CTCTGCACTC CATGTCGGCC GAGGTCTTCG GACCCAGCCC GCCCTTCTCG 
TCGCTGTCGG TCAACGGTGG GGCGAGCTAC GGAAACCACC TGTCCCACCC CCCCGAAATG 
AACGAGGCGG CCGTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic analysis of Mayer-Rokitansky-Kuster-Hauser syndrome in a large cohort of families.
Fertility and sterility108(1)145-151.e2(2017 Jul)
Williams LS,Demir Eksi D,Shen Y,Lossie AC,Chorich LP,Sullivan ME,Phillips JA 3rd,Erman M,Kim HG,Alper OM,Layman LC

Identification and functional analysis of a novel LHX1 mutation associated with congenital absence of the uterus and vagina.
Oncotarget8(5)8785-8790(2017 Jan)
Zhang W,Zhou X,Liu L,Zhu Y,Liu C,Pan H,Xing Q,Wang J,Wang X,Zhang X,Cao Y,Wang B

TBX6, LHX1 and copy number variations in the complex genetics of M?llerian aplasia.
Orphanet journal of rare diseases8125(2013 Aug)
Sandbacka M,Laivuori H,Freitas ?,Halttunen M,Jokimaa V,Morin-Papunen L,Rosenberg C,Aittom?ki K

Functional genomics identifies drivers of medulloblastoma dissemination.
Cancer research72(19)4944-53(2012 Oct)
Mumert M,Dubuc A,Wu X,Northcott PA,Chin SS,Pedone CA,Taylor MD,Fults DW

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LHX1 cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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