OR4X1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OR4X1
Entrez Gene ID	390113
Full Name	olfactory receptor family 4 subfamily X member 1 (gene/pseudogene)
Synonyms	OR11-104
General protein information	Preferred Names olfactory receptor family 4 subfamily X member 1 (gene/pseudogene) Names olfactory receptor 4X1 olfactory receptor OR11-104 olfactory receptor, family 4, subfamily X, member 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p11.2
Summary	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004726.1	NP_001004726.1	olfactory receptor 4X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LOC483609	XP_540729.2
Bos taurus (cattle)	OR4X1	NP_001068918.1
Homo sapiens (human)	OR4X1	NP_001004726.1
Rattus norvegicus (Norway rat)	Olr735	NP_001000922.1

Gene Ontology
Bibliography

Related articles in PubMed

Personal receptor repertoires: olfaction as a model.
Olender T, Waszak SM, Viavant M, Khen M, Ben-Asher E, Reyes A, Nativ N, Wysocki CJ, Ge D, Lancet D
BMC genomics13414(2012 Aug)

A nonfunctioning single nucleotide polymorphism in olfactory receptor gene family is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population.
Takabatake N, Toriyama S, Takeishi Y, Shibata Y, Konta T, Inoue S, Abe S, Igarashi A, Tokairin Y, Ishii M, Koyano S, Emi M, Kato T, Kawata S, Kubota I
Biochemical and biophysical research communications364(3)662-7(2007 Dec)

A probabilistic classifier for olfactory receptor pseudogenes.
Menashe I, Aloni R, Lancet D
BMC bioinformatics7393(2006 Aug)

The human olfactory receptor gene family.
Malnic B, Godfrey PA, Buck LB
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

study identified novel nSNP in OR4X1 gene (rs10838851, Tyr273Ter*), which is significantly associated with FEV1.0/FVC value in pulmonary function test in a Japanese population
Title: A nonfunctioning single nucleotide polymorphism in olfactory receptor gene family is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population.

The following OR4X1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OR4X1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu29146	NM_001004726.1 Latest version!	Homo sapiens olfactory receptor family 4 subfamily X member 1 (gene/pseudogene) (OR4X1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OR4X1 ( NM_001004726.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001004726.1 Homo sapiens olfactory receptor family 4 subfamily X member 1 (gene/pseudogene) (OR4X1), mRNA.

Price & Availability↑

CloneID	OHu29146
Clone ID Related Accession (Same CDS sequence)	NM_001004726.1
Accession Version	NM_001004726.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 918bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-29
Organism	Homo sapiens(human)
Product	olfactory receptor 4X1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC026975.5. On Sep 19, 2004 this sequence version replaced XM_372376.2. Sequence Note: This gene is a segregating pseudogene. This RefSeq represents the protein encoded by the reference genome allele, which is predicted to be functional according to the Classifier for Olfactory Receptor Pseudogenes. CCDS Note: This olfactory receptor gene is a segregating pseudogene (PMID:22908908), where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele that is predicted to be non-functional. This CCDS is being retained because the Classifier for Olfactory Receptor Pseudogenes (CORP) predicts the reference genome allele to be functional. ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000320048.1/ ENSP00000321506.1 polymorphic pseudogene :: PMID: 22908908 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGTTGCTA CAAACAATGT GACTGAAATA ATTTTCGTGG GATTTTCCCA GAATTGGAGT 
GAGCAGAGGG TCATTTCTGT GATGTTTCTC CTCATGTACA CAGCTGTTGT GCTGGGCAAT 
GGCCTCATTG TGGTGACCAT CCTGGCCAGC AAAGTGCTCA CCTCCCCCAT GTATTTCTTT 
CTCAGCTACT TATCCTTTGT GGAGATCTGC TACTGTTCTG TCATGGCCCC CAAGCTTATC 
TTTGACTCCT TTATCAAGAG GAAAGTCATT TCTCTCAAGG GCTGCCTCAC ACAGATGTTT 
TCCCTCCATT TCTTTGGTGG CACTGAGGCC TTTCTCCTGA TGGTGATGGC CTATGACCGC 
TATGTGGCCA TCTGCAAGCC CTTGCACTAC ATGGCCATCA TGAACCAGCG AATGTGTGGT 
CTCCTCGTGA GGATAGCATG GGGCGGGGGC CTGCTGCATT CTGTTGGGCA AACCTTCCTG 
ATTTTCCAGC TCCCGTTCTG TGGCCCCAAC ATCATGGACC ACTACTTCTG TGATGTCCAC 
CCAGTGCTGG AGCTGGCCTG CGCAGACACC TTCTTCATTA GCCTGCTGAT CATCACCAAT 
GGCGGCTCCA TCTCCGTAGT CAGTTTCTTC GTGCTGATGG CTTCCTACCT GATCATCCTG 
CACTTCCTGA GAAGCCACAA CTTGGAGGGG CAGCACAAGG CCCTCTCCAC CTGTGCCTCT 
CATGTCACAG TTGTCGACCT GTTCTTCATA CCTTGCTCCT TGGTCTATAT TAGGCCCTGT 
GTCACCCTCC CTGCAGACAA GATAGTTGCT GTATTTTATA CAGTGGTCAC ACCTCTCTTA 
AACCCTGTGA TTTACTCCTT CAGGAATGCT GAAGTGAAAA ATGCCATGAG GAGATTTATT 
GGGGGAAAAG TAATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004726.1
CDS	1..918
Translation	MVATNNVTEIIFVGFSQNWSEQRVISVMFLLMYTAVVLGNGLIVVTILASKVLTSPMYFFLSYLSFVEICYCSVMAPKLIFDSFIKRKVISLKGCLTQMFSLHFFGGTEAFLLMVMAYDRYVAICKPLHYMAIMNQRMCGLLVRIAWGGGLLHSVGQTFLIFQLPFCGPNIMDHYFCDVHPVLELACADTFFISLLIITNGGSISVVSFFVLMASYLIILHFLRSHNLEGQHKALSTCASHVTVVDLFFIPCSLVYIRPCVTLPADKIVAVFYTVVTPLLNPVIYSFRNAEVKNAMRRFIGGKVI

Target ORF information:

RefSeq Version	NM_001004726.1
Organism	Homo sapiens(human)
Definition	Homo sapiens olfactory receptor family 4 subfamily X member 1 (gene/pseudogene) (OR4X1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004726.1

ORF Insert Sequence:

ATGGTTGCTA CAAACAATGT GACTGAAATA ATTTTCGTGG GATTTTCCCA GAATTGGAGT 
GAGCAGAGGG TCATTTCTGT GATGTTTCTC CTCATGTACA CAGCTGTTGT GCTGGGCAAT 
GGCCTCATTG TGGTGACCAT CCTGGCCAGC AAAGTGCTCA CCTCCCCCAT GTATTTCTTT 
CTCAGCTACT TATCCTTTGT GGAGATCTGC TACTGTTCTG TCATGGCCCC CAAGCTTATC 
TTTGACTCCT TTATCAAGAG GAAAGTCATT TCTCTCAAGG GCTGCCTCAC ACAGATGTTT 
TCCCTCCATT TCTTTGGTGG CACTGAGGCC TTTCTCCTGA TGGTGATGGC CTATGACCGC 
TATGTGGCCA TCTGCAAGCC CTTGCACTAC ATGGCCATCA TGAACCAGCG AATGTGTGGT 
CTCCTCGTGA GGATAGCATG GGGCGGGGGC CTGCTGCATT CTGTTGGGCA AACCTTCCTG 
ATTTTCCAGC TCCCGTTCTG TGGCCCCAAC ATCATGGACC ACTACTTCTG TGATGTCCAC 
CCAGTGCTGG AGCTGGCCTG CGCAGACACC TTCTTCATTA GCCTGCTGAT CATCACCAAT 
GGCGGCTCCA TCTCCGTAGT CAGTTTCTTC GTGCTGATGG CTTCCTACCT GATCATCCTG 
CACTTCCTGA GAAGCCACAA CTTGGAGGGG CAGCACAAGG CCCTCTCCAC CTGTGCCTCT 
CATGTCACAG TTGTCGACCT GTTCTTCATA CCTTGCTCCT TGGTCTATAT TAGGCCCTGT 
GTCACCCTCC CTGCAGACAA GATAGTTGCT GTATTTTATA CAGTGGTCAC ACCTCTCTTA 
AACCCTGTGA TTTACTCCTT CAGGAATGCT GAAGTGAAAA ATGCCATGAG GAGATTTATT 
GGGGGAAAAG TAATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Personal receptor repertoires: olfaction as a model.
BMC genomics13414(2012 Aug)
Olender T,Waszak SM,Viavant M,Khen M,Ben-Asher E,Reyes A,Nativ N,Wysocki CJ,Ge D,Lancet D

A nonfunctioning single nucleotide polymorphism in olfactory receptor gene family is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population.
Biochemical and biophysical research communications364(3)662-7(2007 Dec)
Takabatake N,Toriyama S,Takeishi Y,Shibata Y,Konta T,Inoue S,Abe S,Igarashi A,Tokairin Y,Ishii M,Koyano S,Emi M,Kato T,Kawata S,Kubota I

A probabilistic classifier for olfactory receptor pseudogenes.
BMC bioinformatics7393(2006 Aug)
Menashe I,Aloni R,Lancet D

The human olfactory receptor gene family.
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)
Malnic B,Godfrey PA,Buck LB

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OR4X1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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