LEUTX cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LEUTX
Entrez Gene ID	342900
Full Name	leucine twenty homeobox
General protein information	Preferred Names leucine twenty homeobox Names leucine-twenty homeobox arginine-fifty homeobox-like pseudogene putative leucine-twenty homeobox
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2

mRNA and Protein(s)

mRNA	Protein	Name
NM_001143832.1	NP_001137304.1	leucine-twenty homeobox

Pathways from BioSystems

Homologies

Homo sapiens (human)	LEUTX	NP_001137304.1
Pan troglodytes (chimpanzee)	LEUTX	XP_530043.3
	LOC699783	XP_001088235.2

Gene Ontology
Bibliography

Related articles in PubMed

The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation.
Jouhilahti EM, Madissoon E, Vesterlund L, T?h?nen V, Krjut?kov K, Plaza Reyes A, Petropoulos S, M?nsson R, Linnarsson S, B?rglin T, Lanner F, Hovatta O, Katayama S, Kere J
Development (Cambridge, England)143(19)3459-3469(2016 10)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

Classification and nomenclature of all human homeobox genes.
Holland PW, Booth HA, Bruford EA
BMC biology547(2007 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following LEUTX gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LEUTX cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu31855	NM_001143832.1 Latest version!	Homo sapiens leucine twenty homeobox (LEUTX), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LEUTX ( NM_001143832.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001137304.1 Homo sapiens leucine twenty homeobox (LEUTX), mRNA.

Price & Availability↑

CloneID	OHu31855
Clone ID Related Accession (Same CDS sequence)	NM_001143832.1
Accession Version	NM_001143832.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 507bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-16
Organism	Homo sapiens(human)
Product	leucine-twenty homeobox
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CH471126.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: CR746510.1, H02655.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCACCCAA GTTTGGCTAC AATGGGGAAA CTGGCTTCAA AGCTACAACT TGATCTATCC 
GTAGTAAAGA TCTGGTTCAA GAACCAGCGT GCCAAATGGA AGAGGCAGCA GCGGCAGCAA 
ATGCAGACAC GGCCATCACT AGGGCCAGCA AACCAGACAA CTTCAGTGAA GAAGGAGGAG 
ACTCCCTCAG CCATAACTAC TGCAAACATT CGTCCAGTAA GTCCTGGAAT CTCTGATGCA 
AATGACCATG ATCTACGTGA GCCTTCTGGT ATCAAGAATC CTGGAGGAGC CAGCGCCTCT 
GCGAGGGTTT CATCCTGGGA TTCTCAGTCA TATGACATTG AACAGATATG TCTGGGGGCT 
TCAAATCCTC CTTGGGCCTC CACTCTCTTT GAAATAGATG AATTTGTAAA GATCTATGAC 
TTGCCAGGGG AAGATGACAC CAGCAGCCTA AATCAATATC TTTTTCCAGT ATGCCTTGAG 
TATGACCAGC TCCAATCTTC AGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001137304.1
CDS	166..672
Translation	MHPSLATMGKLASKLQLDLSVVKIWFKNQRAKWKRQQRQQMQTRPSLGPANQTTSVKKEETPSAITTANIRPVSPGISDANDHDLREPSGIKNPGGASASARVSSWDSQSYDIEQICLGASNPPWASTLFEIDEFVKIYDLPGEDDTSSLNQYLFPVCLEYDQLQSSV

Target ORF information:

RefSeq Version	NM_001143832.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine twenty homeobox (LEUTX), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001143832.1

ORF Insert Sequence:

ATGCACCCAA GTTTGGCTAC AATGGGGAAA CTGGCTTCAA AGCTACAACT TGATCTATCC 
GTAGTAAAGA TCTGGTTCAA GAACCAGCGT GCCAAATGGA AGAGGCAGCA GCGGCAGCAA 
ATGCAGACAC GGCCATCACT AGGGCCAGCA AACCAGACAA CTTCAGTGAA GAAGGAGGAG 
ACTCCCTCAG CCATAACTAC TGCAAACATT CGTCCAGTAA GTCCTGGAAT CTCTGATGCA 
AATGACCATG ATCTACGTGA GCCTTCTGGT ATCAAGAATC CTGGAGGAGC CAGCGCCTCT 
GCGAGGGTTT CATCCTGGGA TTCTCAGTCA TATGACATTG AACAGATATG TCTGGGGGCT 
TCAAATCCTC CTTGGGCCTC CACTCTCTTT GAAATAGATG AATTTGTAAA GATCTATGAC 
TTGCCAGGGG AAGATGACAC CAGCAGCCTA AATCAATATC TTTTTCCAGT ATGCCTTGAG 
TATGACCAGC TCCAATCTTC AGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation.
Development (Cambridge, England)143(19)3459-3469(2016 10)
Jouhilahti EM,Madissoon E,Vesterlund L,T?h?nen V,Krjut?kov K,Plaza Reyes A,Petropoulos S,M?nsson R,Linnarsson S,B?rglin T,Lanner F,Hovatta O,Katayama S,Kere J

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM

Classification and nomenclature of all human homeobox genes.
BMC biology547(2007 Oct)
Holland PW,Booth HA,Bruford EA