CYP2S1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CYP2S1
Entrez Gene ID	29785
Full Name	cytochrome P450 family 2 subfamily S member 1
Synonyms	CYPIIS1
General protein information	Preferred Names cytochrome P450 family 2 subfamily S member 1 Names cytochrome P450 2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 cytochrome P540, subfamily IIS, polypeptide 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.2
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. [provided by RefSeq, Jul 2008].
Disorder MIM:	611529

mRNA and Protein(s)

mRNA	Protein	Name
NM_030622.8	NP_085125.1	cytochrome P450 2S1 precursor
NM_030622.7	NP_085125.1	cytochrome P450 2S1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cyp2s1	NP_083051.1
Homo sapiens (human)	CYP2S1	NP_085125.1
Canis lupus familiaris (dog)	CYP2S1	XP_541605.2
Pan troglodytes (chimpanzee)	LOC739649	XP_001147950.3
Bos taurus (cattle)	CYP2S1	NP_001093836.1
Rattus norvegicus (Norway rat)	Cyp2s1	NP_001100965.1

Gene Ontology
Bibliography

Related articles in PubMed

Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines.
Yang C, Zhou Q, Li M, Tong X, Sun J, Qing Y, Sun L, Yang X, Hu X, Jiang J, Yan X, He L, Wan C
Scientific reports633078(2016 Sep)

CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of ?-catenin signaling.
Yang C, Li C, Li M, Tong X, Hu X, Yang X, Yan X, He L, Wan C
Experimental cell research331(2)377-86(2015 Feb)

A transcriptomic approach to elucidate the physiological significance of human cytochrome P450 2S1 in bronchial epithelial cells.
Madanayake TW, Lindquist IE, Devitt NP, Mudge J, Rowland AM
BMC genomics14833(2013 Nov)

Differential gene expression in HIV-infected individuals following ART.
Massanella M, Singhania A, Beliakova-Bethell N, Pier R, Lada SM, White CH, P?rez-Santiago J, Blanco J, Richman DD, Little SJ, Woelk CH
Antiviral research100(2)420-8(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CYP2S1 regulates colorectal cancer growth through associated with prostaglandin E2-mediated activation of beta-catenin signaling.
Title: CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of ?-catenin signaling.

The P450 2S1 may be involved in the reductive detoxication of several of the activated products of carcinogenic aromatic amines and heterocyclic aromatic amines.
Title: Reduction of aromatic and heterocyclic aromatic N-hydroxylamines by human cytochrome P450 2S1.

found that CYP inhibition and siRNA-mediated downregulation of CYP2S1 increased macrophage phagocytosis
Title: Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaques.

NADPH-P450 reductase
Title: Biotransformation of (+)-fenchone by Salmonella typhimurium OY1002/2A6 expressing human CYP2A6 and NADPH-P450 reductase.

The reduction in CYP2S1 expression doubled intracellular PGE(2) levels.
Title: Cytochrome P450 2S1 depletion enhances cell proliferation and migration in bronchial epithelial cells, in part, through modulation of prostaglandin E(2) synthesis.

The following CYP2S1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CYP2S1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu67369	NM_030622.8 Latest version!	Homo sapiens cytochrome P450 family 2 subfamily S member 1 (CYP2S1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$265.30 $379.00
View Old Accession Versions >>
OHu67369	NM_030622.7	Homo sapiens cytochrome P450 family 2 subfamily S member 1 (CYP2S1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CYP2S1 ( NM_030622.8 ) cDNA ORF clone, Homo sapiens(human) -> NP_085125.1 Homo sapiens cytochrome P450 family 2 subfamily S member 1 (CYP2S1), mRNA.

Price & Availability↑

CloneID	OHu67369
Clone ID Related Accession (Same CDS sequence)	NM_030622.8 , NM_030622.7
Accession Version	NM_030622.8 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	cytochrome P450 2S1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP284240.1, BC033691.1 and AY358603.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_030622.7. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358603.1, SRR1803615.81606.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000310054.9/ ENSP00000308032.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGCGA CCGGCACCTG GGCGCTGCTG CTGGCGCTGG CGCTGCTCCT GCTGCTGACG 
CTGGCGCTGT CCGGGACCAG GGCCCGAGGC CACCTGCCCC CCGGGCCCAC GCCGCTACCA 
CTGCTGGGAA ACCTCCTGCA GCTACGGCCC GGGGCGCTGT ATTCAGGGCT CATGCGGCTG 
AGTAAGAAGT ACGGACCGGT GTTCACCATC TACCTGGGAC CCTGGCGGCC TGTGGTGGTC 
CTGGTTGGGC AGGAGGCTGT GCGGGAGGCC CTGGGAGGTC AGGCTGAGGA GTTCAGCGGC 
CGGGGAACCG TAGCGATGCT GGAAGGGACT TTTGATGGCC ATGGGGTTTT CTTCTCCAAC 
GGGGAGCGGT GGAGGCAGCT GAGGAAGTTT ACCATGCTTG CTCTGCGGGA CCTGGGCATG 
GGGAAGCGAG AAGGCGAGGA GCTGATCCAG GCGGAGGCCC GGTGTCTGGT GGAGACATTC 
CAGGGGACAG AAGGACGCCC ATTCGATCCC TCCCTGCTGC TGGCCCAGGC CACCTCCAAC 
GTAGTCTGCT CCCTCCTCTT TGGCCTCCGC TTCTCCTATG AGGATAAGGA GTTCCAGGCC 
GTGGTCCGGG CAGCTGGTGG TACCCTGCTG GGAGTCAGCT CCCAGGGGGG TCAGACCTAC 
GAGATGTTCT CCTGGTTCCT GCGGCCCCTG CCAGGCCCCC ACAAGCAGCT CCTCCACCAC 
GTCAGCACCT TGGCTGCCTT CACAGTCCGG CAGGTGCAGC AGCACCAGGG GAACCTGGAT 
GCTTCGGGCC CCGCACGTGA CCTTGTCGAT GCCTTCCTGC TGAAGATGGC ACAGGAGGAA 
CAAAACCCAG GCACAGAATT CACCAACAAG AACATGCTGA TGACAGTCAT TTATTTGCTG 
TTTGCTGGGA CGATGACGGT CAGCACCACG GTCGGCTATA CCCTCCTGCT CCTGATGAAA 
TACCCTCATG TCCAAAAGTG GGTACGTGAG GAGCTGAATC GGGAGCTGGG GGCTGGCCAG 
GCACCAAGCC TAGGGGACCG TACCCGCCTC CCTTACACCG ACGCGGTTCT GCATGAGGCG 
CAGCGGCTGC TGGCGCTGGT GCCCATGGGA ATACCCCGCA CCCTCATGCG GACCACCCGC 
TTCCGAGGGT ACACCCTGCC CCAGGGCACG GAGGTCTTCC CCCTCCTTGG CTCCATCCTG 
CATGACCCCA ACATCTTCAA GCACCCAGAA GAGTTCAACC CAGACCGTTT CCTGGATGCA 
GATGGACGGT TCAGGAAGCA TGAGGCGTTC CTGCCCTTCT CCTTAGGGAA GCGTGTCTGC 
CTTGGAGAGG GCCTGGCAAA AGCGGAGCTC TTCCTCTTCT TCACCACCAT CCTACAAGCC 
TTCTCCCTGG AGAGCCCGTG CCCGCCGGAC ACCCTGAGCC TCAAGCCCAC CGTCAGTGGC 
CTTTTCAACA TTCCCCCAGC CTTCCAGCTG CAAGTCCGTC CCACTGACCT TCACTCCACC 
ACGCAGACCA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_085125.1
CDS	47..1561
Translation	MEATGTWALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAFSLESPCPPDTLSLKPTVSGLFNIPPAFQLQVRPTDLHSTTQTR

Target ORF information:

RefSeq Version	NM_030622.8
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily S member 1 (CYP2S1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030622.8

ORF Insert Sequence:

ATGGAGGCGA CCGGCACCTG GGCGCTGCTG CTGGCGCTGG CGCTGCTCCT GCTGCTGACG 
CTGGCGCTGT CCGGGACCAG GGCCCGAGGC CACCTGCCCC CCGGGCCCAC GCCGCTACCA 
CTGCTGGGAA ACCTCCTGCA GCTACGGCCC GGGGCGCTGT ATTCAGGGCT CATGCGGCTG 
AGTAAGAAGT ACGGACCGGT GTTCACCATC TACCTGGGAC CCTGGCGGCC TGTGGTGGTC 
CTGGTTGGGC AGGAGGCTGT GCGGGAGGCC CTGGGAGGTC AGGCTGAGGA GTTCAGCGGC 
CGGGGAACCG TAGCGATGCT GGAAGGGACT TTTGATGGCC ATGGGGTTTT CTTCTCCAAC 
GGGGAGCGGT GGAGGCAGCT GAGGAAGTTT ACCATGCTTG CTCTGCGGGA CCTGGGCATG 
GGGAAGCGAG AAGGCGAGGA GCTGATCCAG GCGGAGGCCC GGTGTCTGGT GGAGACATTC 
CAGGGGACAG AAGGACGCCC ATTCGATCCC TCCCTGCTGC TGGCCCAGGC CACCTCCAAC 
GTAGTCTGCT CCCTCCTCTT TGGCCTCCGC TTCTCCTATG AGGATAAGGA GTTCCAGGCC 
GTGGTCCGGG CAGCTGGTGG TACCCTGCTG GGAGTCAGCT CCCAGGGGGG TCAGACCTAC 
GAGATGTTCT CCTGGTTCCT GCGGCCCCTG CCAGGCCCCC ACAAGCAGCT CCTCCACCAC 
GTCAGCACCT TGGCTGCCTT CACAGTCCGG CAGGTGCAGC AGCACCAGGG GAACCTGGAT 
GCTTCGGGCC CCGCACGTGA CCTTGTCGAT GCCTTCCTGC TGAAGATGGC ACAGGAGGAA 
CAAAACCCAG GCACAGAATT CACCAACAAG AACATGCTGA TGACAGTCAT TTATTTGCTG 
TTTGCTGGGA CGATGACGGT CAGCACCACG GTCGGCTATA CCCTCCTGCT CCTGATGAAA 
TACCCTCATG TCCAAAAGTG GGTACGTGAG GAGCTGAATC GGGAGCTGGG GGCTGGCCAG 
GCACCAAGCC TAGGGGACCG TACCCGCCTC CCTTACACCG ACGCGGTTCT GCATGAGGCG 
CAGCGGCTGC TGGCGCTGGT GCCCATGGGA ATACCCCGCA CCCTCATGCG GACCACCCGC 
TTCCGAGGGT ACACCCTGCC CCAGGGCACG GAGGTCTTCC CCCTCCTTGG CTCCATCCTG 
CATGACCCCA ACATCTTCAA GCACCCAGAA GAGTTCAACC CAGACCGTTT CCTGGATGCA 
GATGGACGGT TCAGGAAGCA TGAGGCGTTC CTGCCCTTCT CCTTAGGGAA GCGTGTCTGC 
CTTGGAGAGG GCCTGGCAAA AGCGGAGCTC TTCCTCTTCT TCACCACCAT CCTACAAGCC 
TTCTCCCTGG AGAGCCCGTG CCCGCCGGAC ACCCTGAGCC TCAAGCCCAC CGTCAGTGGC 
CTTTTCAACA TTCCCCCAGC CTTCCAGCTG CAAGTCCGTC CCACTGACCT TCACTCCACC 
ACGCAGACCA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CYP2S1 ( NM_030622.7 ) cDNA ORF clone, Homo sapiens(human) -> NP_085125.1 Homo sapiens cytochrome P450 family 2 subfamily S member 1 (CYP2S1), mRNA.

Price & Availability↑

CloneID	OHu67369
Clone ID Related Accession (Same CDS sequence)	NM_030622.8 , NM_030622.7
Accession Version	NM_030622.7	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	cytochrome P450 2S1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP284240.1, BC033691.1 and AY358603.1. This sequence is a reference standard in the RefSeqGene project. On Jan 13, 2015 this sequence version replaced NM_030622.6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358603.1, SRR1803615.81606.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGCGA CCGGCACCTG GGCGCTGCTG CTGGCGCTGG CGCTGCTCCT GCTGCTGACG 
CTGGCGCTGT CCGGGACCAG GGCCCGAGGC CACCTGCCCC CCGGGCCCAC GCCGCTACCA 
CTGCTGGGAA ACCTCCTGCA GCTACGGCCC GGGGCGCTGT ATTCAGGGCT CATGCGGCTG 
AGTAAGAAGT ACGGACCGGT GTTCACCATC TACCTGGGAC CCTGGCGGCC TGTGGTGGTC 
CTGGTTGGGC AGGAGGCTGT GCGGGAGGCC CTGGGAGGTC AGGCTGAGGA GTTCAGCGGC 
CGGGGAACCG TAGCGATGCT GGAAGGGACT TTTGATGGCC ATGGGGTTTT CTTCTCCAAC 
GGGGAGCGGT GGAGGCAGCT GAGGAAGTTT ACCATGCTTG CTCTGCGGGA CCTGGGCATG 
GGGAAGCGAG AAGGCGAGGA GCTGATCCAG GCGGAGGCCC GGTGTCTGGT GGAGACATTC 
CAGGGGACAG AAGGACGCCC ATTCGATCCC TCCCTGCTGC TGGCCCAGGC CACCTCCAAC 
GTAGTCTGCT CCCTCCTCTT TGGCCTCCGC TTCTCCTATG AGGATAAGGA GTTCCAGGCC 
GTGGTCCGGG CAGCTGGTGG TACCCTGCTG GGAGTCAGCT CCCAGGGGGG TCAGACCTAC 
GAGATGTTCT CCTGGTTCCT GCGGCCCCTG CCAGGCCCCC ACAAGCAGCT CCTCCACCAC 
GTCAGCACCT TGGCTGCCTT CACAGTCCGG CAGGTGCAGC AGCACCAGGG GAACCTGGAT 
GCTTCGGGCC CCGCACGTGA CCTTGTCGAT GCCTTCCTGC TGAAGATGGC ACAGGAGGAA 
CAAAACCCAG GCACAGAATT CACCAACAAG AACATGCTGA TGACAGTCAT TTATTTGCTG 
TTTGCTGGGA CGATGACGGT CAGCACCACG GTCGGCTATA CCCTCCTGCT CCTGATGAAA 
TACCCTCATG TCCAAAAGTG GGTACGTGAG GAGCTGAATC GGGAGCTGGG GGCTGGCCAG 
GCACCAAGCC TAGGGGACCG TACCCGCCTC CCTTACACCG ACGCGGTTCT GCATGAGGCG 
CAGCGGCTGC TGGCGCTGGT GCCCATGGGA ATACCCCGCA CCCTCATGCG GACCACCCGC 
TTCCGAGGGT ACACCCTGCC CCAGGGCACG GAGGTCTTCC CCCTCCTTGG CTCCATCCTG 
CATGACCCCA ACATCTTCAA GCACCCAGAA GAGTTCAACC CAGACCGTTT CCTGGATGCA 
GATGGACGGT TCAGGAAGCA TGAGGCGTTC CTGCCCTTCT CCTTAGGGAA GCGTGTCTGC 
CTTGGAGAGG GCCTGGCAAA AGCGGAGCTC TTCCTCTTCT TCACCACCAT CCTACAAGCC 
TTCTCCCTGG AGAGCCCGTG CCCGCCGGAC ACCCTGAGCC TCAAGCCCAC CGTCAGTGGC 
CTTTTCAACA TTCCCCCAGC CTTCCAGCTG CAAGTCCGTC CCACTGACCT TCACTCCACC 
ACGCAGACCA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_085125.1
CDS	59..1573
Translation	MEATGTWALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAFSLESPCPPDTLSLKPTVSGLFNIPPAFQLQVRPTDLHSTTQTR

Target ORF information:

RefSeq Version	NM_030622.7
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome P450 family 2 subfamily S member 1 (CYP2S1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_030622.7

ORF Insert Sequence:

ATGGAGGCGA CCGGCACCTG GGCGCTGCTG CTGGCGCTGG CGCTGCTCCT GCTGCTGACG 
CTGGCGCTGT CCGGGACCAG GGCCCGAGGC CACCTGCCCC CCGGGCCCAC GCCGCTACCA 
CTGCTGGGAA ACCTCCTGCA GCTACGGCCC GGGGCGCTGT ATTCAGGGCT CATGCGGCTG 
AGTAAGAAGT ACGGACCGGT GTTCACCATC TACCTGGGAC CCTGGCGGCC TGTGGTGGTC 
CTGGTTGGGC AGGAGGCTGT GCGGGAGGCC CTGGGAGGTC AGGCTGAGGA GTTCAGCGGC 
CGGGGAACCG TAGCGATGCT GGAAGGGACT TTTGATGGCC ATGGGGTTTT CTTCTCCAAC 
GGGGAGCGGT GGAGGCAGCT GAGGAAGTTT ACCATGCTTG CTCTGCGGGA CCTGGGCATG 
GGGAAGCGAG AAGGCGAGGA GCTGATCCAG GCGGAGGCCC GGTGTCTGGT GGAGACATTC 
CAGGGGACAG AAGGACGCCC ATTCGATCCC TCCCTGCTGC TGGCCCAGGC CACCTCCAAC 
GTAGTCTGCT CCCTCCTCTT TGGCCTCCGC TTCTCCTATG AGGATAAGGA GTTCCAGGCC 
GTGGTCCGGG CAGCTGGTGG TACCCTGCTG GGAGTCAGCT CCCAGGGGGG TCAGACCTAC 
GAGATGTTCT CCTGGTTCCT GCGGCCCCTG CCAGGCCCCC ACAAGCAGCT CCTCCACCAC 
GTCAGCACCT TGGCTGCCTT CACAGTCCGG CAGGTGCAGC AGCACCAGGG GAACCTGGAT 
GCTTCGGGCC CCGCACGTGA CCTTGTCGAT GCCTTCCTGC TGAAGATGGC ACAGGAGGAA 
CAAAACCCAG GCACAGAATT CACCAACAAG AACATGCTGA TGACAGTCAT TTATTTGCTG 
TTTGCTGGGA CGATGACGGT CAGCACCACG GTCGGCTATA CCCTCCTGCT CCTGATGAAA 
TACCCTCATG TCCAAAAGTG GGTACGTGAG GAGCTGAATC GGGAGCTGGG GGCTGGCCAG 
GCACCAAGCC TAGGGGACCG TACCCGCCTC CCTTACACCG ACGCGGTTCT GCATGAGGCG 
CAGCGGCTGC TGGCGCTGGT GCCCATGGGA ATACCCCGCA CCCTCATGCG GACCACCCGC 
TTCCGAGGGT ACACCCTGCC CCAGGGCACG GAGGTCTTCC CCCTCCTTGG CTCCATCCTG 
CATGACCCCA ACATCTTCAA GCACCCAGAA GAGTTCAACC CAGACCGTTT CCTGGATGCA 
GATGGACGGT TCAGGAAGCA TGAGGCGTTC CTGCCCTTCT CCTTAGGGAA GCGTGTCTGC 
CTTGGAGAGG GCCTGGCAAA AGCGGAGCTC TTCCTCTTCT TCACCACCAT CCTACAAGCC 
TTCTCCCTGG AGAGCCCGTG CCCGCCGGAC ACCCTGAGCC TCAAGCCCAC CGTCAGTGGC 
CTTTTCAACA TTCCCCCAGC CTTCCAGCTG CAAGTCCGTC CCACTGACCT TCACTCCACC 
ACGCAGACCA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines.
Scientific reports633078(2016 Sep)
Yang C,Zhou Q,Li M,Tong X,Sun J,Qing Y,Sun L,Yang X,Hu X,Jiang J,Yan X,He L,Wan C

CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of ?-catenin signaling.
Experimental cell research331(2)377-86(2015 Feb)
Yang C,Li C,Li M,Tong X,Hu X,Yang X,Yan X,He L,Wan C

A transcriptomic approach to elucidate the physiological significance of human cytochrome P450 2S1 in bronchial epithelial cells.
BMC genomics14833(2013 Nov)
Madanayake TW,Lindquist IE,Devitt NP,Mudge J,Rowland AM

Differential gene expression in HIV-infected individuals following ART.
Antiviral research100(2)420-8(2013 Nov)
Massanella M,Singhania A,Beliakova-Bethell N,Pier R,Lada SM,White CH,P?rez-Santiago J,Blanco J,Richman DD,Little SJ,Woelk CH

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CYP2S1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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