NAP1L5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NAP1L5
Entrez Gene ID	266812
Full Name	nucleosome assembly protein 1 like 5
Synonyms	DRLM
General protein information	Preferred Names nucleosome assembly protein 1 like 5 Names nucleosome assembly protein 1-like 5 down-regulated in liver malignancy
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q22.1\|4q21-q22
Summary	This gene encodes a protein that shares sequence similarity to nucleosome assembly factors, but may be localized to the cytoplasm rather than the nucleus. Expression of this gene is downregulated in hepatocellular carcinomas. This gene is located within a differentially methylated region (DMR) and is imprinted and paternally expressed. There is a related pseudogene on chromosome 4. [provided by RefSeq, Nov 2015].
Disorder MIM:	612203

mRNA and Protein(s)

mRNA	Protein	Name
NM_153757.4	NP_715638.1	nucleosome assembly protein 1-like 5
NM_153757.2	NP_715638.1	nucleosome assembly protein 1-like 5
NM_153757.3	NP_715638.1	nucleosome assembly protein 1-like 5

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	NAP1L5	XP_001160970.1
Homo sapiens (human)	NAP1L5	NP_715638.1
Mus musculus (house mouse)	Nap1l5	NP_067407.1
	NAP1L5	XP_001100967.1
Canis lupus familiaris (dog)	NAP1L5	XP_005639230.1
Bos taurus (cattle)	NAP1L5	NP_001071346.1
Rattus norvegicus (Norway rat)	Nap1l5	NP_001037758.1

Gene Ontology
Bibliography

Related articles in PubMed

A case-by-case evolutionary analysis of four imprinted retrogenes.
McCole RB, Loughran NB, Chahal M, Fernandes LP, Roberts RG, Fraternali F, O'Connell MJ, Oakey RJ
Evolution; international journal of organic evolution65(5)1413-27(2011 May)

A novel approach identifies new differentially methylated regions (DMRs) associated with imprinted genes.
Choufani S, Shapiro JS, Susiarjo M, Butcher DT, Grafodatskaya D, Lou Y, Ferreira JC, Pinto D, Scherer SW, Shaffer LG, Coullin P, Caniggia I, Beyene J, Slim R, Bartolomei MS, Weksberg R
Genome research21(3)465-76(2011 Mar)

Large copy-number variations are enriched in cases with moderate to extreme obesity.
Wang K, Li WD, Glessner JT, Grant SF, Hakonarson H, Price RA
Diabetes59(10)2690-4(2010 Oct)

A screen for retrotransposed imprinted genes reveals an association between X chromosome homology and maternal germ-line methylation.
Wood AJ, Roberts RG, Monk D, Moore GE, Schulz R, Oakey RJ
PLoS genetics3(2)e20(2007 Feb)

Down-regulation of a novel gene, DRLM, in human liver malignancy from 4q22 that encodes a NAP-like protein.
Harada H, Nagai H, Ezura Y, Yokota T, Ohsawa I, Yamaguchi K, Ohue C, Tsuneizumi M, Mikami I, Terada Y, Yabe A, Emi M
Gene296(1-2)171-7(2002 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: Large copy-number variations are enriched in cases with moderate to extreme obesity.

The following NAP1L5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NAP1L5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00292	NM_153757.4 Latest version!	Homo sapiens nucleosome assembly protein 1 like 5 (NAP1L5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu00292	NM_153757.2	Homo sapiens nucleosome assembly protein 1-like 5 (NAP1L5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu00292	NM_153757.3	Homo sapiens nucleosome assembly protein 1 like 5 (NAP1L5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NAP1L5 ( NM_153757.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_715638.1 Homo sapiens nucleosome assembly protein 1 like 5 (NAP1L5), mRNA.

Price & Availability↑

CloneID	OHu00292
Clone ID Related Accession (Same CDS sequence)	NM_153757.4 , NM_153757.2 , NM_153757.3
Accession Version	NM_153757.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	nucleosome assembly protein 1-like 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA041186.1, AK054689.1, BC039416.1 and CK301058.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_153757.3. ##Evidence-Data-START## Transcript is intronless :: SRR1803613.199550.1, SRR7410570.236144.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## imprinted gene :: PMID: 17291163 MANE Ensembl match :: ENST00000323061.7/ ENSP00000320488.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGACT CGGAAAACCA GGGGCCTGCG GAGCCTAGCC AGGCGGCGGC AGCGGCGGAG 
GCAGCGGCAG AGGAGGTAAT GGCGGAAGGC GGTGCGCAGG GTGGAGACTG TGACAGCGCG 
GCTGGTGACC CTGACAGCGC GGCTGGTCAG ATGGCTGAGG AGCCCCAGAC CCCTGCAGAG 
AATGCCCCAA AGCCGAAAAA TGACTTTATC GAGAGCCTGC CTAATTCGGT GAAATGCCGA 
GTCCTGGCCC TCAAAAAGCT GCAGAAGCGA TGCGATAAGA TAGAAGCCAA ATTTGATAAG 
GAATTTCAGG CTCTGGAAAA AAAGTATAAT GACATCTATA AGCCCCTACT CGCCAAGATC 
CAAGAGCTCA CCGGCGAGAT GGAGGGGTGT GCATGGACCT TGGAGGGGGA GGAGGAGGAG 
GAAGAGGAGT ACGAGGATGA CGAGGAGGAG GGGGAAGACG AGGAGGAGGA GGAGGCTGCG 
GCAGAGGCTG CCGCGGGGGC CAAACATGAC GATGCCCACG CCGAGATGCC TGATGACGCC 
AAGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_715638.1
CDS	76..624
Translation	MADSENQGPAEPSQAAAAAEAAAEEVMAEGGAQGGDCDSAAGDPDSAAGQMAEEPQTPAENAPKPKNDFIESLPNSVKCRVLALKKLQKRCDKIEAKFDKEFQALEKKYNDIYKPLLAKIQELTGEMEGCAWTLEGEEEEEEEYEDDEEEGEDEEEEEAAAEAAAGAKHDDAHAEMPDDAKK

Target ORF information:

RefSeq Version	NM_153757.4
Organism	Homo sapiens(human)
Definition	Homo sapiens nucleosome assembly protein 1 like 5 (NAP1L5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153757.4

ORF Insert Sequence:

ATGGCCGACT CGGAAAACCA GGGGCCTGCG GAGCCTAGCC AGGCGGCGGC AGCGGCGGAG 
GCAGCGGCAG AGGAGGTAAT GGCGGAAGGC GGTGCGCAGG GTGGAGACTG TGACAGCGCG 
GCTGGTGACC CTGACAGCGC GGCTGGTCAG ATGGCTGAGG AGCCCCAGAC CCCTGCAGAG 
AATGCCCCAA AGCCGAAAAA TGACTTTATC GAGAGCCTGC CTAATTCGGT GAAATGCCGA 
GTCCTGGCCC TCAAAAAGCT GCAGAAGCGA TGCGATAAGA TAGAAGCCAA ATTTGATAAG 
GAATTTCAGG CTCTGGAAAA AAAGTATAAT GACATCTATA AGCCCCTACT CGCCAAGATC 
CAAGAGCTCA CCGGCGAGAT GGAGGGGTGT GCATGGACCT TGGAGGGGGA GGAGGAGGAG 
GAAGAGGAGT ACGAGGATGA CGAGGAGGAG GGGGAAGACG AGGAGGAGGA GGAGGCTGCG 
GCAGAGGCTG CCGCGGGGGC CAAACATGAC GATGCCCACG CCGAGATGCC TGATGACGCC 
AAGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NAP1L5 ( NM_153757.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_715638.1 Homo sapiens nucleosome assembly protein 1-like 5 (NAP1L5), mRNA.

Price & Availability↑

CloneID	OHu00292
Clone ID Related Accession (Same CDS sequence)	NM_153757.4 , NM_153757.2 , NM_153757.3
Accession Version	NM_153757.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2014-02-14
Organism	Homo sapiens(Human)
Product	nucleosome assembly protein 1-like 5
Comment

ATGGCCGACT CGGAAAACCA GGGGCCTGCG GAGCCTAGCC AGGCGGCGGC AGCGGCGGAG 
GCAGCGGCAG AGGAGGTAAT GGCGGAAGGC GGTGCGCAGG GTGGAGACTG TGACAGCGCG 
GCTGGTGACC CTGACAGCGC GGCTGGTCAG ATGGCTGAGG AGCCCCAGAC CCCTGCAGAG 
AATGCCCCAA AGCCGAAAAA TGACTTTATC GAGAGCCTGC CTAATTCGGT GAAATGCCGA 
GTCCTGGCCC TCAAAAAGCT GCAGAAGCGA TGCGATAAGA TAGAAGCCAA ATTTGATAAG 
GAATTTCAGG CTCTGGAAAA AAAGTATAAT GACATCTATA AGCCCCTACT CGCCAAGATC 
CAAGAGCTCA CCGGCGAGAT GGAGGGGTGT GCATGGACCT TGGAGGGGGA GGAGGAGGAG 
GAAGAGGAGT ACGAGGATGA CGAGGAGGAG GGGGAAGACG AGGAGGAGGA GGAGGCTGCG 
GCAGAGGCTG CCGCGGGGGC CAAACATGAC GATGCCCACG CCGAGATGCC TGATGACGCC 
AAGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_715638.1
Translation	MADSENQGPAEPSQAAAAAEAAAEEVMAEGGAQGGDCDSAAGDPDSAAGQMAEEPQTPAENAPKPKNDFIESLPNSVKCRVLALKKLQKRCDKIEAKFDKEFQALEKKYNDIYKPLLAKIQELTGEMEGCAWTLEGEEEEEEEYEDDEEEGEDEEEEEAAAEAAAGAKHDDAHAEMPDDAKK

Target ORF information:

RefSeq Version	NM_153757.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens nucleosome assembly protein 1-like 5 (NAP1L5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153757.2

ORF Insert Sequence:

ATGGCCGACT CGGAAAACCA GGGGCCTGCG GAGCCTAGCC AGGCGGCGGC AGCGGCGGAG 
GCAGCGGCAG AGGAGGTAAT GGCGGAAGGC GGTGCGCAGG GTGGAGACTG TGACAGCGCG 
GCTGGTGACC CTGACAGCGC GGCTGGTCAG ATGGCTGAGG AGCCCCAGAC CCCTGCAGAG 
AATGCCCCAA AGCCGAAAAA TGACTTTATC GAGAGCCTGC CTAATTCGGT GAAATGCCGA 
GTCCTGGCCC TCAAAAAGCT GCAGAAGCGA TGCGATAAGA TAGAAGCCAA ATTTGATAAG 
GAATTTCAGG CTCTGGAAAA AAAGTATAAT GACATCTATA AGCCCCTACT CGCCAAGATC 
CAAGAGCTCA CCGGCGAGAT GGAGGGGTGT GCATGGACCT TGGAGGGGGA GGAGGAGGAG 
GAAGAGGAGT ACGAGGATGA CGAGGAGGAG GGGGAAGACG AGGAGGAGGA GGAGGCTGCG 
GCAGAGGCTG CCGCGGGGGC CAAACATGAC GATGCCCACG CCGAGATGCC TGATGACGCC 
AAGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NAP1L5 ( NM_153757.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_715638.1 Homo sapiens nucleosome assembly protein 1 like 5 (NAP1L5), mRNA.

Price & Availability↑

CloneID	OHu00292
Clone ID Related Accession (Same CDS sequence)	NM_153757.4 , NM_153757.2 , NM_153757.3
Accession Version	NM_153757.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	nucleosome assembly protein 1-like 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AI494339.1, DA041186.1, AK054689.1, BC039416.1 and CK301058.1. This sequence is a reference standard in the RefSeqGene project. On Nov 17, 2015 this sequence version replaced NM_153757.2. ##RefSeq-Attributes-START## imprinted gene :: PMID: 17291163 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGACT CGGAAAACCA GGGGCCTGCG GAGCCTAGCC AGGCGGCGGC AGCGGCGGAG 
GCAGCGGCAG AGGAGGTAAT GGCGGAAGGC GGTGCGCAGG GTGGAGACTG TGACAGCGCG 
GCTGGTGACC CTGACAGCGC GGCTGGTCAG ATGGCTGAGG AGCCCCAGAC CCCTGCAGAG 
AATGCCCCAA AGCCGAAAAA TGACTTTATC GAGAGCCTGC CTAATTCGGT GAAATGCCGA 
GTCCTGGCCC TCAAAAAGCT GCAGAAGCGA TGCGATAAGA TAGAAGCCAA ATTTGATAAG 
GAATTTCAGG CTCTGGAAAA AAAGTATAAT GACATCTATA AGCCCCTACT CGCCAAGATC 
CAAGAGCTCA CCGGCGAGAT GGAGGGGTGT GCATGGACCT TGGAGGGGGA GGAGGAGGAG 
GAAGAGGAGT ACGAGGATGA CGAGGAGGAG GGGGAAGACG AGGAGGAGGA GGAGGCTGCG 
GCAGAGGCTG CCGCGGGGGC CAAACATGAC GATGCCCACG CCGAGATGCC TGATGACGCC 
AAGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_715638.1
CDS	482..1030
Translation	MADSENQGPAEPSQAAAAAEAAAEEVMAEGGAQGGDCDSAAGDPDSAAGQMAEEPQTPAENAPKPKNDFIESLPNSVKCRVLALKKLQKRCDKIEAKFDKEFQALEKKYNDIYKPLLAKIQELTGEMEGCAWTLEGEEEEEEEYEDDEEEGEDEEEEEAAAEAAAGAKHDDAHAEMPDDAKK

Target ORF information:

RefSeq Version	NM_153757.3
Organism	Homo sapiens(human)
Definition	Homo sapiens nucleosome assembly protein 1 like 5 (NAP1L5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_153757.3

ORF Insert Sequence:

ATGGCCGACT CGGAAAACCA GGGGCCTGCG GAGCCTAGCC AGGCGGCGGC AGCGGCGGAG 
GCAGCGGCAG AGGAGGTAAT GGCGGAAGGC GGTGCGCAGG GTGGAGACTG TGACAGCGCG 
GCTGGTGACC CTGACAGCGC GGCTGGTCAG ATGGCTGAGG AGCCCCAGAC CCCTGCAGAG 
AATGCCCCAA AGCCGAAAAA TGACTTTATC GAGAGCCTGC CTAATTCGGT GAAATGCCGA 
GTCCTGGCCC TCAAAAAGCT GCAGAAGCGA TGCGATAAGA TAGAAGCCAA ATTTGATAAG 
GAATTTCAGG CTCTGGAAAA AAAGTATAAT GACATCTATA AGCCCCTACT CGCCAAGATC 
CAAGAGCTCA CCGGCGAGAT GGAGGGGTGT GCATGGACCT TGGAGGGGGA GGAGGAGGAG 
GAAGAGGAGT ACGAGGATGA CGAGGAGGAG GGGGAAGACG AGGAGGAGGA GGAGGCTGCG 
GCAGAGGCTG CCGCGGGGGC CAAACATGAC GATGCCCACG CCGAGATGCC TGATGACGCC 
AAGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A case-by-case evolutionary analysis of four imprinted retrogenes.
Evolution; international journal of organic evolution65(5)1413-27(2011 May)
McCole RB,Loughran NB,Chahal M,Fernandes LP,Roberts RG,Fraternali F,O'Connell MJ,Oakey RJ

A novel approach identifies new differentially methylated regions (DMRs) associated with imprinted genes.
Genome research21(3)465-76(2011 Mar)
Choufani S,Shapiro JS,Susiarjo M,Butcher DT,Grafodatskaya D,Lou Y,Ferreira JC,Pinto D,Scherer SW,Shaffer LG,Coullin P,Caniggia I,Beyene J,Slim R,Bartolomei MS,Weksberg R

Large copy-number variations are enriched in cases with moderate to extreme obesity.
Diabetes59(10)2690-4(2010 Oct)
Wang K,Li WD,Glessner JT,Grant SF,Hakonarson H,Price RA

A screen for retrotransposed imprinted genes reveals an association between X chromosome homology and maternal germ-line methylation.
PLoS genetics3(2)e20(2007 Feb)
Wood AJ,Roberts RG,Monk D,Moore GE,Schulz R,Oakey RJ

Down-regulation of a novel gene, DRLM, in human liver malignancy from 4q22 that encodes a NAP-like protein.
Gene296(1-2)171-7(2002 Aug)
Harada H,Nagai H,Ezura Y,Yokota T,Ohsawa I,Yamaguchi K,Ohue C,Tsuneizumi M,Mikami I,Terada Y,Yabe A,Emi M

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NAP1L5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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