TBC1D10B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TBC1D10B
Entrez Gene ID	26000
Full Name	TBC1 domain family member 10B
Synonyms	EPI64B,FP2461
General protein information	Preferred Names TBC1 domain family member 10B Names TBC1 domain family member 10B Rab27A-GAPbeta rab27A-GAP-beta
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p11.2
Summary	Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).[supplied by OMIM, Nov 2010].
Disorder MIM:	613620

mRNA and Protein(s)

mRNA	Protein	Name
XM_011545790.2	XP_011544092.1	TBC1 domain family member 10B isoform X2
NM_015527.3	NP_056342.3	TBC1 domain family member 10B
NM_015527.4	NP_056342.3	TBC1 domain family member 10B
XM_011545789.2	XP_011544091.1	TBC1 domain family member 10B isoform X1
XM_011545790.3	XP_011544092.1	TBC1 domain family member 10B isoform X2
XM_011545789.1	XP_011544091.1	TBC1 domain family member 10B isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TBC1D10B	XP_003952876.1
Rattus norvegicus (Norway rat)	Tbc1d10b	NP_001102391.1
	LOC711696	XP_001100532.2
Homo sapiens (human)	TBC1D10B	NP_056342.3
Canis lupus familiaris (dog)	LOC489935	XP_547055.3
Bos taurus (cattle)	TBC1D10B	NP_001192700.1
Mus musculus (house mouse)	Tbc1d10b	NP_653105.3

Gene Ontology
Bibliography

Related articles in PubMed

All members of the EPI64 subfamily of TBC/RabGAPs also have GAP activities towards Ras.
Nagai H, Yasuda S, Ohba Y, Fukuda M, Nakamura T
Journal of biochemistry153(3)283-8(2013 Mar)

Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.
Popovic D, Akutsu M, Novak I, Harper JW, Behrends C, Dikic I
Molecular and cellular biology32(9)1733-44(2012 May)

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C.
Hsu C, Morohashi Y, Yoshimura S, Manrique-Hoyos N, Jung S, Lauterbach MA, Bakhti M, Gr?nborg M, M?bius W, Rhee J, Barr FA, Simons M
The Journal of cell biology189(2)223-32(2010 Apr)

Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.
Ishibashi K, Kanno E, Itoh T, Fukuda M
Genes to cells : devoted to molecular & cellular mechanisms14(1)41-52(2009 Jan)

Functional dissection of Rab GTPases involved in primary cilium formation.
Yoshimura S, Egerer J, Fuchs E, Haas AK, Barr FA
The Journal of cell biology178(3)363-9(2007 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that EPI64A and B, which are ubiquitously expressed members of the EPI64 subfamily, inactivate Ras and certain Rabs at the periphery of cells.
Title: All members of the EPI64 subfamily of TBC/RabGAPs also have GAP activities towards Ras.

The following TBC1D10B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TBC1D10B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07035	NM_015527.4 Latest version!	Homo sapiens TBC1 domain family member 10B (TBC1D10B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$409.50-$573.30 $819.00
OHu66692	XM_011545789.2 Latest version!	Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu66693	XM_011545790.3 Latest version!	Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu07035	NM_015527.3	Homo sapiens TBC1 domain family member 10B (TBC1D10B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$409.50-$573.30 $819.00
OHu66693	XM_011545790.2	Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu66692	XM_011545789.1	Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TBC1D10B ( NM_015527.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056342.3 Homo sapiens TBC1 domain family member 10B (TBC1D10B), mRNA.

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CloneID	OHu07035
Clone ID Related Accession (Same CDS sequence)	NM_015527.3 , NM_015527.4
Accession Version	NM_015527.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2427bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	TBC1 domain family member 10B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AI672923.1, BY795947.2, BC072453.1 and BC050523.2. On Feb 11, 2008 this sequence version replaced NM_015527.2. ##Evidence-Data-START## Transcript exon combination :: BC098419.1, AK023192.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTAGAG 
AGCTCCATTC CCGTGGACGT GGCTCGGCAG CGGGAGCTCA AATGGCTGGA CATGTTCAGT 
AACTGGGATA AGTGGCTGTC ACGGCGATTC CAGAAGGTGA AGCTGCGCTG CCGGAAGGGG 
ATCCCCTCCT CTCTCAGAGC CAAAGCCTGG CAGTACCTGT CTAATAGCAA GGAACTTCTG 
GAGCAGAACC CAGGAAAGTT TGAGGAGCTG GAACGGGCTC CTGGGGACCC CAAGTGGCTG 
GATGTGATTG AGAAGGACCT GCACCGCCAG TTCCCTTTCC ACGAGATGTT TGCTGCTCGA 
GGGGGGCATG GGCAACAGGA CCTGTACCGA ATCCTGAAGG CCTACACCAT CTACCGGCCT 
GACGAGGGTT ACTGCCAGGC CCAGGCCCCC GTGGCTGCGG TCCTGCTCAT GCACATGCCT 
GCGGAGCAAG CCTTTTGGTG CCTGGTGCAG ATCTGCGACA AGTACCTCCC AGGTTACTAC 
AGTGCAGGGC TGGAGGCCAT TCAGCTGGAC GGGGAGATCT TTTTTGCACT CCTGCGCCGG 
GCCTCCCCGC TGGCGCATCG CCACCTGCGG CGGCAGCGCA TTGACCCTGT GCTCTACATG 
ACGGAGTGGT TCATGTGCAT CTTCGCCCGC ACCCTGCCCT GGGCGTCGGT GCTGCGTGTC 
TGGGACATGT TTTTCTGTGA AGGCGTTAAG ATCATCTTCC GGGTGGCCCT GGTCCTGCTG 
CGCCACACGC TGGGCTCAGT GGAGAAGCTG CGCTCCTGCC AAGGCATGTA TGAGACCATG 
GAGCAGCTGC GTAACCTGCC CCAGCAGTGC ATGCAGGAAG ACTTCCTGGT GCATGAGGTG 
ACCAATCTGC CGGTGACAGA AGCACTGATT GAGCGGGAGA ATGCAGCCCA GCTCAAGAAG 
TGGCGGGAAA CGCGGGGGGA GCTGCAGTAT CGGCCCTCAC GGCGACTGCA TGGGTCCCGG 
GCCATCCACG AGGAGCGCCG GCGGCAACAG CCACCCCTGG GCCCCTCCTC CAGCCTCCTC 
AGCCTCCCTG GCCTCAAGAG CCGAGGCTCC CGGGCAGCTG GAGGGGCCCC GTCCCCGCCG 
CCCCCCGTCC GCAGAGCCAG TGCTGGGCCT GCCCCAGGGC CTGTGGTCAC TGCTGAGGGA 
CTGCATCCAT CCCTTCCCTC ACCCACTGGC AATAGCACCC CCTTGGGTTC CAGCAAGGAG 
ACCCGGAAGC AGGAGAAGGA GCGGCAGAAA CAGGAGAAGG AGCGGCAGAA ACAGGAGAAG 
GAGCGGGAGA AGGAGCGGCA GAAGCAGGAG AAAGAGCGAG AGAAGCAGGA AAAGGAGCGA 
GAGAAGCAGG AGAAGGAGCG GCAGAAGCAG GAGAAGAAGG CTCAAGGCCG GAAGCTTTCG 
CTGCGTCGAA AGGCAGATGG GCCCCCAGGC CCCCATGATG GTGGGGACAG GCCCTCAGCC 
GAGGCCCGGC AGGACGCTTA CTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056342.3
CDS	19..2445
Translation	METGTAPLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARPAWVPGSAETSAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAVVTVTPAPEPAENSQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLALRKTDKYGFLGGSQYSGSLESSIPVDVARQRELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSLLSLPGLKSRGSRAAGGAPSPPPPVRRASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSKETRKQEKERQKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSLRRKADGPPGPHDGGDRPSAEARQDAYF

Target ORF information:

RefSeq Version	NM_015527.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TBC1 domain family member 10B (TBC1D10B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015527.3

ORF Insert Sequence:

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTAGAG 
AGCTCCATTC CCGTGGACGT GGCTCGGCAG CGGGAGCTCA AATGGCTGGA CATGTTCAGT 
AACTGGGATA AGTGGCTGTC ACGGCGATTC CAGAAGGTGA AGCTGCGCTG CCGGAAGGGG 
ATCCCCTCCT CTCTCAGAGC CAAAGCCTGG CAGTACCTGT CTAATAGCAA GGAACTTCTG 
GAGCAGAACC CAGGAAAGTT TGAGGAGCTG GAACGGGCTC CTGGGGACCC CAAGTGGCTG 
GATGTGATTG AGAAGGACCT GCACCGCCAG TTCCCTTTCC ACGAGATGTT TGCTGCTCGA 
GGGGGGCATG GGCAACAGGA CCTGTACCGA ATCCTGAAGG CCTACACCAT CTACCGGCCT 
GACGAGGGTT ACTGCCAGGC CCAGGCCCCC GTGGCTGCGG TCCTGCTCAT GCACATGCCT 
GCGGAGCAAG CCTTTTGGTG CCTGGTGCAG ATCTGCGACA AGTACCTCCC AGGTTACTAC 
AGTGCAGGGC TGGAGGCCAT TCAGCTGGAC GGGGAGATCT TTTTTGCACT CCTGCGCCGG 
GCCTCCCCGC TGGCGCATCG CCACCTGCGG CGGCAGCGCA TTGACCCTGT GCTCTACATG 
ACGGAGTGGT TCATGTGCAT CTTCGCCCGC ACCCTGCCCT GGGCGTCGGT GCTGCGTGTC 
TGGGACATGT TTTTCTGTGA AGGCGTTAAG ATCATCTTCC GGGTGGCCCT GGTCCTGCTG 
CGCCACACGC TGGGCTCAGT GGAGAAGCTG CGCTCCTGCC AAGGCATGTA TGAGACCATG 
GAGCAGCTGC GTAACCTGCC CCAGCAGTGC ATGCAGGAAG ACTTCCTGGT GCATGAGGTG 
ACCAATCTGC CGGTGACAGA AGCACTGATT GAGCGGGAGA ATGCAGCCCA GCTCAAGAAG 
TGGCGGGAAA CGCGGGGGGA GCTGCAGTAT CGGCCCTCAC GGCGACTGCA TGGGTCCCGG 
GCCATCCACG AGGAGCGCCG GCGGCAACAG CCACCCCTGG GCCCCTCCTC CAGCCTCCTC 
AGCCTCCCTG GCCTCAAGAG CCGAGGCTCC CGGGCAGCTG GAGGGGCCCC GTCCCCGCCG 
CCCCCCGTCC GCAGAGCCAG TGCTGGGCCT GCCCCAGGGC CTGTGGTCAC TGCTGAGGGA 
CTGCATCCAT CCCTTCCCTC ACCCACTGGC AATAGCACCC CCTTGGGTTC CAGCAAGGAG 
ACCCGGAAGC AGGAGAAGGA GCGGCAGAAA CAGGAGAAGG AGCGGCAGAA ACAGGAGAAG 
GAGCGGGAGA AGGAGCGGCA GAAGCAGGAG AAAGAGCGAG AGAAGCAGGA AAAGGAGCGA 
GAGAAGCAGG AGAAGGAGCG GCAGAAGCAG GAGAAGAAGG CTCAAGGCCG GAAGCTTTCG 
CTGCGTCGAA AGGCAGATGG GCCCCCAGGC CCCCATGATG GTGGGGACAG GCCCTCAGCC 
GAGGCCCGGC AGGACGCTTA CTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TBC1D10B ( NM_015527.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056342.3 Homo sapiens TBC1 domain family member 10B (TBC1D10B), mRNA.

Price & Availability↑

CloneID	OHu07035
Clone ID Related Accession (Same CDS sequence)	NM_015527.3 , NM_015527.4
Accession Version	NM_015527.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2427bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	TBC1 domain family member 10B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC106782.5, AI672923.1, BY795947.2 and BC072453.1. On Nov 23, 2018 this sequence version replaced NM_015527.3. ##Evidence-Data-START## Transcript exon combination :: AK023192.1, SRR3476690.928065.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000409939.8/ ENSP00000386538.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTAGAG 
AGCTCCATTC CCGTGGACGT GGCTCGGCAG CGGGAGCTCA AATGGCTGGA CATGTTCAGT 
AACTGGGATA AGTGGCTGTC ACGGCGATTC CAGAAGGTGA AGCTGCGCTG CCGGAAGGGG 
ATCCCCTCCT CTCTCAGAGC CAAAGCCTGG CAGTACCTGT CTAATAGCAA GGAACTTCTG 
GAGCAGAACC CAGGAAAGTT TGAGGAGCTG GAACGGGCTC CTGGGGACCC CAAGTGGCTG 
GATGTGATTG AGAAGGACCT GCACCGCCAG TTCCCTTTCC ACGAGATGTT TGCTGCTCGA 
GGGGGGCATG GGCAACAGGA CCTGTACCGA ATCCTGAAGG CCTACACCAT CTACCGGCCT 
GACGAGGGTT ACTGCCAGGC CCAGGCCCCC GTGGCTGCGG TCCTGCTCAT GCACATGCCT 
GCGGAGCAAG CCTTTTGGTG CCTGGTGCAG ATCTGCGACA AGTACCTCCC AGGTTACTAC 
AGTGCAGGGC TGGAGGCCAT TCAGCTGGAC GGGGAGATCT TTTTTGCACT CCTGCGCCGG 
GCCTCCCCGC TGGCGCATCG CCACCTGCGG CGGCAGCGCA TTGACCCTGT GCTCTACATG 
ACGGAGTGGT TCATGTGCAT CTTCGCCCGC ACCCTGCCCT GGGCGTCGGT GCTGCGTGTC 
TGGGACATGT TTTTCTGTGA AGGCGTTAAG ATCATCTTCC GGGTGGCCCT GGTCCTGCTG 
CGCCACACGC TGGGCTCAGT GGAGAAGCTG CGCTCCTGCC AAGGCATGTA TGAGACCATG 
GAGCAGCTGC GTAACCTGCC CCAGCAGTGC ATGCAGGAAG ACTTCCTGGT GCATGAGGTG 
ACCAATCTGC CGGTGACAGA AGCACTGATT GAGCGGGAGA ATGCAGCCCA GCTCAAGAAG 
TGGCGGGAAA CGCGGGGGGA GCTGCAGTAT CGGCCCTCAC GGCGACTGCA TGGGTCCCGG 
GCCATCCACG AGGAGCGCCG GCGGCAACAG CCACCCCTGG GCCCCTCCTC CAGCCTCCTC 
AGCCTCCCTG GCCTCAAGAG CCGAGGCTCC CGGGCAGCTG GAGGGGCCCC GTCCCCGCCG 
CCCCCCGTCC GCAGAGCCAG TGCTGGGCCT GCCCCAGGGC CTGTGGTCAC TGCTGAGGGA 
CTGCATCCAT CCCTTCCCTC ACCCACTGGC AATAGCACCC CCTTGGGTTC CAGCAAGGAG 
ACCCGGAAGC AGGAGAAGGA GCGGCAGAAA CAGGAGAAGG AGCGGCAGAA ACAGGAGAAG 
GAGCGGGAGA AGGAGCGGCA GAAGCAGGAG AAAGAGCGAG AGAAGCAGGA AAAGGAGCGA 
GAGAAGCAGG AGAAGGAGCG GCAGAAGCAG GAGAAGAAGG CTCAAGGCCG GAAGCTTTCG 
CTGCGTCGAA AGGCAGATGG GCCCCCAGGC CCCCATGATG GTGGGGACAG GCCCTCAGCC 
GAGGCCCGGC AGGACGCTTA CTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056342.3
CDS	312..2738
Translation	METGTAPLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARPAWVPGSAETSAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAVVTVTPAPEPAENSQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLALRKTDKYGFLGGSQYSGSLESSIPVDVARQRELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSLLSLPGLKSRGSRAAGGAPSPPPPVRRASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSKETRKQEKERQKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSLRRKADGPPGPHDGGDRPSAEARQDAYF

Target ORF information:

RefSeq Version	NM_015527.4
Organism	Homo sapiens(human)
Definition	Homo sapiens TBC1 domain family member 10B (TBC1D10B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015527.4

ORF Insert Sequence:

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTAGAG 
AGCTCCATTC CCGTGGACGT GGCTCGGCAG CGGGAGCTCA AATGGCTGGA CATGTTCAGT 
AACTGGGATA AGTGGCTGTC ACGGCGATTC CAGAAGGTGA AGCTGCGCTG CCGGAAGGGG 
ATCCCCTCCT CTCTCAGAGC CAAAGCCTGG CAGTACCTGT CTAATAGCAA GGAACTTCTG 
GAGCAGAACC CAGGAAAGTT TGAGGAGCTG GAACGGGCTC CTGGGGACCC CAAGTGGCTG 
GATGTGATTG AGAAGGACCT GCACCGCCAG TTCCCTTTCC ACGAGATGTT TGCTGCTCGA 
GGGGGGCATG GGCAACAGGA CCTGTACCGA ATCCTGAAGG CCTACACCAT CTACCGGCCT 
GACGAGGGTT ACTGCCAGGC CCAGGCCCCC GTGGCTGCGG TCCTGCTCAT GCACATGCCT 
GCGGAGCAAG CCTTTTGGTG CCTGGTGCAG ATCTGCGACA AGTACCTCCC AGGTTACTAC 
AGTGCAGGGC TGGAGGCCAT TCAGCTGGAC GGGGAGATCT TTTTTGCACT CCTGCGCCGG 
GCCTCCCCGC TGGCGCATCG CCACCTGCGG CGGCAGCGCA TTGACCCTGT GCTCTACATG 
ACGGAGTGGT TCATGTGCAT CTTCGCCCGC ACCCTGCCCT GGGCGTCGGT GCTGCGTGTC 
TGGGACATGT TTTTCTGTGA AGGCGTTAAG ATCATCTTCC GGGTGGCCCT GGTCCTGCTG 
CGCCACACGC TGGGCTCAGT GGAGAAGCTG CGCTCCTGCC AAGGCATGTA TGAGACCATG 
GAGCAGCTGC GTAACCTGCC CCAGCAGTGC ATGCAGGAAG ACTTCCTGGT GCATGAGGTG 
ACCAATCTGC CGGTGACAGA AGCACTGATT GAGCGGGAGA ATGCAGCCCA GCTCAAGAAG 
TGGCGGGAAA CGCGGGGGGA GCTGCAGTAT CGGCCCTCAC GGCGACTGCA TGGGTCCCGG 
GCCATCCACG AGGAGCGCCG GCGGCAACAG CCACCCCTGG GCCCCTCCTC CAGCCTCCTC 
AGCCTCCCTG GCCTCAAGAG CCGAGGCTCC CGGGCAGCTG GAGGGGCCCC GTCCCCGCCG 
CCCCCCGTCC GCAGAGCCAG TGCTGGGCCT GCCCCAGGGC CTGTGGTCAC TGCTGAGGGA 
CTGCATCCAT CCCTTCCCTC ACCCACTGGC AATAGCACCC CCTTGGGTTC CAGCAAGGAG 
ACCCGGAAGC AGGAGAAGGA GCGGCAGAAA CAGGAGAAGG AGCGGCAGAA ACAGGAGAAG 
GAGCGGGAGA AGGAGCGGCA GAAGCAGGAG AAAGAGCGAG AGAAGCAGGA AAAGGAGCGA 
GAGAAGCAGG AGAAGGAGCG GCAGAAGCAG GAGAAGAAGG CTCAAGGCCG GAAGCTTTCG 
CTGCGTCGAA AGGCAGATGG GCCCCCAGGC CCCCATGATG GTGGGGACAG GCCCTCAGCC 
GAGGCCCGGC AGGACGCTTA CTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TBC1D10B ( XM_011545789.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544091.1 Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu66692
Clone ID Related Accession (Same CDS sequence)	XM_011545789.2 , XM_011545789.1
Accession Version	XM_011545789.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2112bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	TBC1 domain family member 10B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011545789.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTGCAA 
CAGGACCTGT ACCGAATCCT GAAGGCCTAC ACCATCTACC GGCCTGACGA GGGTTACTGC 
CAGGCCCAGG CCCCCGTGGC TGCGGTCCTG CTCATGCACA TGCCTGCGGA GCAAGCCTTT 
TGGTGCCTGG TGCAGATCTG CGACAAGTAC CTCCCAGGTT ACTACAGTGC AGGGCTGGAG 
GCCATTCAGC TGGACGGGGA GATCTTTTTT GCACTCCTGC GCCGGGCCTC CCCGCTGGCG 
CATCGCCACC TGCGGCGGCA GCGCATTGAC CCTGTGCTCT ACATGACGGA GTGGTTCATG 
TGCATCTTCG CCCGCACCCT GCCCTGGGCG TCGGTGCTGC GTGTCTGGGA CATGTTTTTC 
TGTGAAGGCG TTAAGATCAT CTTCCGGGTG GCCCTGGTCC TGCTGCGCCA CACGCTGGGC 
TCAGTGGAGA AGCTGCGCTC CTGCCAAGGC ATGTATGAGA CCATGGAGCA GCTGCGTAAC 
CTGCCCCAGC AGTGCATGCA GGAAGACTTC CTGGTGCATG AGGTGACCAA TCTGCCGGTG 
ACAGAAGCAC TGATTGAGCG GGAGAATGCA GCCCAGCTCA AGAAGTGGCG GGAAACGCGG 
GGGGAGCTGC AGTATCGGCC CTCACGGCGA CTGCATGGGT CCCGGGCCAT CCACGAGGAG 
CGCCGGCGGC AACAGCCACC CCTGGGCCCC TCCTCCAGCC TCCTCAGCCT CCCTGGCCTC 
AAGAGCCGAG GCTCCCGGGC AGCTGGAGGG GCCCCGTCCC CGCCGCCCCC CGTCCGCAGA 
GCCAGTGCTG GGCCTGCCCC AGGGCCTGTG GTCACTGCTG AGGGACTGCA TCCATCCCTT 
CCCTCACCCA CTGGCAATAG CACCCCCTTG GGTTCCAGCA AGGAGACCCG GAAGCAGGAG 
AAGGAGCGGC AGAAACAGGA GAAGGAGCGG CAGAAACAGG AGAAGGAGCG GGAGAAGGAG 
CGGCAGAAGC AGGAGAAAGA GCGAGAGAAG CAGGAAAAGG AGCGAGAGAA GCAGGAGAAG 
GAGCGGCAGA AGCAGGAGAA GAAGGCTCAA GGCCGGAAGC TTTCGCTGCG TCGAAAGGCA 
GATGGGCCCC CAGGCCCCCA TGATGGTGGG GACAGGCCCT CAGCCGAGGC CCGGCAGGAC 
GCTTACTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011544091.1
CDS	284..2395
Translation	METGTAPLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARPAWVPGSAETSAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAVVTVTPAPEPAENSQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLALRKTDKYGFLGGSQYSGSLQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSLLSLPGLKSRGSRAAGGAPSPPPPVRRASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSKETRKQEKERQKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSLRRKADGPPGPHDGGDRPSAEARQDAYF

Target ORF information:

RefSeq Version	XM_011545789.2
Organism	Homo sapiens(human)
Definition	Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545789.2

ORF Insert Sequence:

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTGCAA 
CAGGACCTGT ACCGAATCCT GAAGGCCTAC ACCATCTACC GGCCTGACGA GGGTTACTGC 
CAGGCCCAGG CCCCCGTGGC TGCGGTCCTG CTCATGCACA TGCCTGCGGA GCAAGCCTTT 
TGGTGCCTGG TGCAGATCTG CGACAAGTAC CTCCCAGGTT ACTACAGTGC AGGGCTGGAG 
GCCATTCAGC TGGACGGGGA GATCTTTTTT GCACTCCTGC GCCGGGCCTC CCCGCTGGCG 
CATCGCCACC TGCGGCGGCA GCGCATTGAC CCTGTGCTCT ACATGACGGA GTGGTTCATG 
TGCATCTTCG CCCGCACCCT GCCCTGGGCG TCGGTGCTGC GTGTCTGGGA CATGTTTTTC 
TGTGAAGGCG TTAAGATCAT CTTCCGGGTG GCCCTGGTCC TGCTGCGCCA CACGCTGGGC 
TCAGTGGAGA AGCTGCGCTC CTGCCAAGGC ATGTATGAGA CCATGGAGCA GCTGCGTAAC 
CTGCCCCAGC AGTGCATGCA GGAAGACTTC CTGGTGCATG AGGTGACCAA TCTGCCGGTG 
ACAGAAGCAC TGATTGAGCG GGAGAATGCA GCCCAGCTCA AGAAGTGGCG GGAAACGCGG 
GGGGAGCTGC AGTATCGGCC CTCACGGCGA CTGCATGGGT CCCGGGCCAT CCACGAGGAG 
CGCCGGCGGC AACAGCCACC CCTGGGCCCC TCCTCCAGCC TCCTCAGCCT CCCTGGCCTC 
AAGAGCCGAG GCTCCCGGGC AGCTGGAGGG GCCCCGTCCC CGCCGCCCCC CGTCCGCAGA 
GCCAGTGCTG GGCCTGCCCC AGGGCCTGTG GTCACTGCTG AGGGACTGCA TCCATCCCTT 
CCCTCACCCA CTGGCAATAG CACCCCCTTG GGTTCCAGCA AGGAGACCCG GAAGCAGGAG 
AAGGAGCGGC AGAAACAGGA GAAGGAGCGG CAGAAACAGG AGAAGGAGCG GGAGAAGGAG 
CGGCAGAAGC AGGAGAAAGA GCGAGAGAAG CAGGAAAAGG AGCGAGAGAA GCAGGAGAAG 
GAGCGGCAGA AGCAGGAGAA GAAGGCTCAA GGCCGGAAGC TTTCGCTGCG TCGAAAGGCA 
GATGGGCCCC CAGGCCCCCA TGATGGTGGG GACAGGCCCT CAGCCGAGGC CCGGCAGGAC 
GCTTACTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TBC1D10B ( XM_011545789.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544091.1 Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu66692
Clone ID Related Accession (Same CDS sequence)	XM_011545789.2 , XM_011545789.1
Accession Version	XM_011545789.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2112bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	TBC1 domain family member 10B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTGCAA 
CAGGACCTGT ACCGAATCCT GAAGGCCTAC ACCATCTACC GGCCTGACGA GGGTTACTGC 
CAGGCCCAGG CCCCCGTGGC TGCGGTCCTG CTCATGCACA TGCCTGCGGA GCAAGCCTTT 
TGGTGCCTGG TGCAGATCTG CGACAAGTAC CTCCCAGGTT ACTACAGTGC AGGGCTGGAG 
GCCATTCAGC TGGACGGGGA GATCTTTTTT GCACTCCTGC GCCGGGCCTC CCCGCTGGCG 
CATCGCCACC TGCGGCGGCA GCGCATTGAC CCTGTGCTCT ACATGACGGA GTGGTTCATG 
TGCATCTTCG CCCGCACCCT GCCCTGGGCG TCGGTGCTGC GTGTCTGGGA CATGTTTTTC 
TGTGAAGGCG TTAAGATCAT CTTCCGGGTG GCCCTGGTCC TGCTGCGCCA CACGCTGGGC 
TCAGTGGAGA AGCTGCGCTC CTGCCAAGGC ATGTATGAGA CCATGGAGCA GCTGCGTAAC 
CTGCCCCAGC AGTGCATGCA GGAAGACTTC CTGGTGCATG AGGTGACCAA TCTGCCGGTG 
ACAGAAGCAC TGATTGAGCG GGAGAATGCA GCCCAGCTCA AGAAGTGGCG GGAAACGCGG 
GGGGAGCTGC AGTATCGGCC CTCACGGCGA CTGCATGGGT CCCGGGCCAT CCACGAGGAG 
CGCCGGCGGC AACAGCCACC CCTGGGCCCC TCCTCCAGCC TCCTCAGCCT CCCTGGCCTC 
AAGAGCCGAG GCTCCCGGGC AGCTGGAGGG GCCCCGTCCC CGCCGCCCCC CGTCCGCAGA 
GCCAGTGCTG GGCCTGCCCC AGGGCCTGTG GTCACTGCTG AGGGACTGCA TCCATCCCTT 
CCCTCACCCA CTGGCAATAG CACCCCCTTG GGTTCCAGCA AGGAGACCCG GAAGCAGGAG 
AAGGAGCGGC AGAAACAGGA GAAGGAGCGG CAGAAACAGG AGAAGGAGCG GGAGAAGGAG 
CGGCAGAAGC AGGAGAAAGA GCGAGAGAAG CAGGAAAAGG AGCGAGAGAA GCAGGAGAAG 
GAGCGGCAGA AGCAGGAGAA GAAGGCTCAA GGCCGGAAGC TTTCGCTGCG TCGAAAGGCA 
GATGGGCCCC CAGGCCCCCA TGATGGTGGG GACAGGCCCT CAGCCGAGGC CCGGCAGGAC 
GCTTACTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011544091.1
CDS	76..2187
Translation	METGTAPLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARPAWVPGSAETSAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAVVTVTPAPEPAENSQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLALRKTDKYGFLGGSQYSGSLQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDGEIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGVKIIFRVALVLLRHTLGSVEKLRSCQGMYETMEQLRNLPQQCMQEDFLVHEVTNLPVTEALIERENAAQLKKWRETRGELQYRPSRRLHGSRAIHEERRRQQPPLGPSSSLLSLPGLKSRGSRAAGGAPSPPPPVRRASAGPAPGPVVTAEGLHPSLPSPTGNSTPLGSSKETRKQEKERQKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSLRRKADGPPGPHDGGDRPSAEARQDAYF

Target ORF information:

RefSeq Version	XM_011545789.1
Organism	Homo sapiens(human)
Definition	Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545789.1

ORF Insert Sequence:

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTGCAA 
CAGGACCTGT ACCGAATCCT GAAGGCCTAC ACCATCTACC GGCCTGACGA GGGTTACTGC 
CAGGCCCAGG CCCCCGTGGC TGCGGTCCTG CTCATGCACA TGCCTGCGGA GCAAGCCTTT 
TGGTGCCTGG TGCAGATCTG CGACAAGTAC CTCCCAGGTT ACTACAGTGC AGGGCTGGAG 
GCCATTCAGC TGGACGGGGA GATCTTTTTT GCACTCCTGC GCCGGGCCTC CCCGCTGGCG 
CATCGCCACC TGCGGCGGCA GCGCATTGAC CCTGTGCTCT ACATGACGGA GTGGTTCATG 
TGCATCTTCG CCCGCACCCT GCCCTGGGCG TCGGTGCTGC GTGTCTGGGA CATGTTTTTC 
TGTGAAGGCG TTAAGATCAT CTTCCGGGTG GCCCTGGTCC TGCTGCGCCA CACGCTGGGC 
TCAGTGGAGA AGCTGCGCTC CTGCCAAGGC ATGTATGAGA CCATGGAGCA GCTGCGTAAC 
CTGCCCCAGC AGTGCATGCA GGAAGACTTC CTGGTGCATG AGGTGACCAA TCTGCCGGTG 
ACAGAAGCAC TGATTGAGCG GGAGAATGCA GCCCAGCTCA AGAAGTGGCG GGAAACGCGG 
GGGGAGCTGC AGTATCGGCC CTCACGGCGA CTGCATGGGT CCCGGGCCAT CCACGAGGAG 
CGCCGGCGGC AACAGCCACC CCTGGGCCCC TCCTCCAGCC TCCTCAGCCT CCCTGGCCTC 
AAGAGCCGAG GCTCCCGGGC AGCTGGAGGG GCCCCGTCCC CGCCGCCCCC CGTCCGCAGA 
GCCAGTGCTG GGCCTGCCCC AGGGCCTGTG GTCACTGCTG AGGGACTGCA TCCATCCCTT 
CCCTCACCCA CTGGCAATAG CACCCCCTTG GGTTCCAGCA AGGAGACCCG GAAGCAGGAG 
AAGGAGCGGC AGAAACAGGA GAAGGAGCGG CAGAAACAGG AGAAGGAGCG GGAGAAGGAG 
CGGCAGAAGC AGGAGAAAGA GCGAGAGAAG CAGGAAAAGG AGCGAGAGAA GCAGGAGAAG 
GAGCGGCAGA AGCAGGAGAA GAAGGCTCAA GGCCGGAAGC TTTCGCTGCG TCGAAAGGCA 
GATGGGCCCC CAGGCCCCCA TGATGGTGGG GACAGGCCCT CAGCCGAGGC CCGGCAGGAC 
GCTTACTTCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TBC1D10B ( XM_011545790.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544092.1 Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu66693
Clone ID Related Accession (Same CDS sequence)	XM_011545790.2 , XM_011545790.3
Accession Version	XM_011545790.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1611bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	TBC1 domain family member 10B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011545790.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTAGAG 
AGCTCCATTC CCGTGGACGT GGCTCGGCAG CGGGAGCTCA AATGGCTGGA CATGTTCAGT 
AACTGGGATA AGTGGCTGTC ACGGCGATTC CAGAAGGTGA AGCTGCGCTG CCGGAAGGGG 
ATCCCCTCCT CTCTCAGAGC CAAAGCCTGG CAGTACCTGT CTAATAGCAA GGAACTTCTG 
GAGCAGAACC CAGGAAAGTT TGAGGAGCTG GAACGGGCTC CTGGGGACCC CAAGTGGCTG 
GATGTGATTG AGAAGGACCT GCACCGCCAG TTCCCTTTCC ACGAGATGTT TGCTGCTCGA 
GGGGGGCATG GGCAACAGGA CCTGTACCGA ATCCTGAAGG CCTACACCAT CTACCGGCCT 
GACGAGGGTT ACTGCCAGGC CCAGGCCCCC GTGGCTGCGG TCCTGCTCAT GCACATGCCT 
GCGGAGCAAG CCTTTTGGTG CCTGGTGCAG ATCTGCGACA AGTACCTCCC AGGTTACTAC 
AGTGCAGGGC TGGCGTTAAG ATCATCTTCC GGGTGGCCCT GGTCCTGCTG CGCCACACGC 
TGGGCTCAGT GGAGAAGCTG CGCTCCTGCC AAGGCATGTA TGAGACCATG GAGCAGCTGC 
GTAACCTGCC CCAGCAGTGC ATGCAGGAAG ACTTCCTGGT GCATGAGGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011544092.1
CDS	76..1686
Translation	METGTAPLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARPAWVPGSAETSAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAVVTVTPAPEPAENSQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLALRKTDKYGFLGGSQYSGSLESSIPVDVARQRELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLALRSSSGWPWSCCATRWAQWRSCAPAKACMRPWSSCVTCPSSACRKTSWCMR

Target ORF information:

RefSeq Version	XM_011545790.2
Organism	Homo sapiens(human)
Definition	Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545790.2

ORF Insert Sequence:

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTAGAG 
AGCTCCATTC CCGTGGACGT GGCTCGGCAG CGGGAGCTCA AATGGCTGGA CATGTTCAGT 
AACTGGGATA AGTGGCTGTC ACGGCGATTC CAGAAGGTGA AGCTGCGCTG CCGGAAGGGG 
ATCCCCTCCT CTCTCAGAGC CAAAGCCTGG CAGTACCTGT CTAATAGCAA GGAACTTCTG 
GAGCAGAACC CAGGAAAGTT TGAGGAGCTG GAACGGGCTC CTGGGGACCC CAAGTGGCTG 
GATGTGATTG AGAAGGACCT GCACCGCCAG TTCCCTTTCC ACGAGATGTT TGCTGCTCGA 
GGGGGGCATG GGCAACAGGA CCTGTACCGA ATCCTGAAGG CCTACACCAT CTACCGGCCT 
GACGAGGGTT ACTGCCAGGC CCAGGCCCCC GTGGCTGCGG TCCTGCTCAT GCACATGCCT 
GCGGAGCAAG CCTTTTGGTG CCTGGTGCAG ATCTGCGACA AGTACCTCCC AGGTTACTAC 
AGTGCAGGGC TGGCGTTAAG ATCATCTTCC GGGTGGCCCT GGTCCTGCTG CGCCACACGC 
TGGGCTCAGT GGAGAAGCTG CGCTCCTGCC AAGGCATGTA TGAGACCATG GAGCAGCTGC 
GTAACCTGCC CCAGCAGTGC ATGCAGGAAG ACTTCCTGGT GCATGAGGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TBC1D10B ( XM_011545790.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544092.1 Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X2, mRNA.

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CloneID	OHu66693
Clone ID Related Accession (Same CDS sequence)	XM_011545790.2 , XM_011545790.3
Accession Version	XM_011545790.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1611bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	TBC1 domain family member 10B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011545790.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTAGAG 
AGCTCCATTC CCGTGGACGT GGCTCGGCAG CGGGAGCTCA AATGGCTGGA CATGTTCAGT 
AACTGGGATA AGTGGCTGTC ACGGCGATTC CAGAAGGTGA AGCTGCGCTG CCGGAAGGGG 
ATCCCCTCCT CTCTCAGAGC CAAAGCCTGG CAGTACCTGT CTAATAGCAA GGAACTTCTG 
GAGCAGAACC CAGGAAAGTT TGAGGAGCTG GAACGGGCTC CTGGGGACCC CAAGTGGCTG 
GATGTGATTG AGAAGGACCT GCACCGCCAG TTCCCTTTCC ACGAGATGTT TGCTGCTCGA 
GGGGGGCATG GGCAACAGGA CCTGTACCGA ATCCTGAAGG CCTACACCAT CTACCGGCCT 
GACGAGGGTT ACTGCCAGGC CCAGGCCCCC GTGGCTGCGG TCCTGCTCAT GCACATGCCT 
GCGGAGCAAG CCTTTTGGTG CCTGGTGCAG ATCTGCGACA AGTACCTCCC AGGTTACTAC 
AGTGCAGGGC TGGCGTTAAG ATCATCTTCC GGGTGGCCCT GGTCCTGCTG CGCCACACGC 
TGGGCTCAGT GGAGAAGCTG CGCTCCTGCC AAGGCATGTA TGAGACCATG GAGCAGCTGC 
GTAACCTGCC CCAGCAGTGC ATGCAGGAAG ACTTCCTGGT GCATGAGGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011544092.1
CDS	276..1886
Translation	METGTAPLVAPPRRHGAPAAPSPPPRGSRAGPVVVVAPGPPVTTATSAPVTLVAPGEARPAWVPGSAETSAPAPAPAPAPAPAVTGSTVVVLTLEASPEAPKPQLPSGPESPEPAAVAGVETSRALAAGADSPKTEEARPSPAPGPGTPTGTPTRTPSRTAPGALTAKPPLAPKPGTTVASGVTARSASGQVTGGHGAAAATSASAGQAPEDPSGPGTGPSGTCEAPVAVVTVTPAPEPAENSQDLGSTSSLGPGISGPRGQAPDTLSYLDSVSLMSGTLESLADDVSSMGSDSEINGLALRKTDKYGFLGGSQYSGSLESSIPVDVARQRELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLALRSSSGWPWSCCATRWAQWRSCAPAKACMRPWSSCVTCPSSACRKTSWCMR

Target ORF information:

RefSeq Version	XM_011545790.3
Organism	Homo sapiens(human)
Definition	Homo sapiens TBC1 domain family member 10B (TBC1D10B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545790.3

ORF Insert Sequence:

ATGGAGACGG GCACGGCGCC CCTGGTGGCC CCGCCGCGCC GTCATGGCGC CCCCGCGGCC 
CCCTCGCCGC CGCCCCGGGG TTCCCGGGCC GGGCCCGTCG TGGTGGTGGC TCCGGGACCT 
CCAGTGACTA CGGCCACTTC GGCCCCCGTC ACCCTGGTGG CCCCCGGGGA GGCGCGGCCC 
GCCTGGGTCC CGGGGTCGGC CGAGACCTCT GCTCCGGCCC CGGCCCCAGC CCCGGCCCCA 
GCCCCGGCTG TCACGGGCAG CACGGTGGTG GTGCTGACCC TGGAGGCCTC GCCCGAAGCC 
CCAAAGCCGC AGCTCCCCTC CGGCCCGGAA TCCCCAGAGC CCGCGGCAGT GGCTGGAGTT 
GAGACATCGA GGGCTCTGGC CGCAGGGGCA GACTCGCCGA AGACAGAGGA GGCTCGACCC 
TCACCCGCCC CAGGACCAGG GACCCCCACC GGGACCCCTA CCAGGACCCC TTCCAGAACG 
GCTCCTGGTG CCCTGACCGC CAAACCCCCG CTTGCCCCCA AGCCGGGAAC CACAGTGGCC 
TCAGGAGTGA CTGCACGGAG TGCATCAGGA CAAGTGACAG GTGGGCATGG AGCTGCCGCA 
GCAACATCAG CATCAGCAGG ACAGGCTCCT GAGGACCCCT CAGGCCCTGG CACAGGCCCC 
TCTGGGACTT GTGAGGCTCC GGTAGCTGTC GTGACCGTGA CCCCAGCTCC GGAGCCTGCT 
GAAAACTCTC AAGACCTGGG CTCCACGTCC AGCCTGGGAC CTGGCATCTC TGGGCCTCGA 
GGGCAGGCCC CGGACACGCT GAGTTACTTG GACTCCGTGA GCCTCATGTC TGGGACCTTG 
GAGTCCTTGG CGGATGATGT GAGCTCCATG GGCTCAGATT CAGAGATAAA CGGGCTGGCC 
CTGCGCAAGA CGGACAAGTA TGGCTTCCTT GGGGGCAGCC AGTACTCGGG CAGCCTAGAG 
AGCTCCATTC CCGTGGACGT GGCTCGGCAG CGGGAGCTCA AATGGCTGGA CATGTTCAGT 
AACTGGGATA AGTGGCTGTC ACGGCGATTC CAGAAGGTGA AGCTGCGCTG CCGGAAGGGG 
ATCCCCTCCT CTCTCAGAGC CAAAGCCTGG CAGTACCTGT CTAATAGCAA GGAACTTCTG 
GAGCAGAACC CAGGAAAGTT TGAGGAGCTG GAACGGGCTC CTGGGGACCC CAAGTGGCTG 
GATGTGATTG AGAAGGACCT GCACCGCCAG TTCCCTTTCC ACGAGATGTT TGCTGCTCGA 
GGGGGGCATG GGCAACAGGA CCTGTACCGA ATCCTGAAGG CCTACACCAT CTACCGGCCT 
GACGAGGGTT ACTGCCAGGC CCAGGCCCCC GTGGCTGCGG TCCTGCTCAT GCACATGCCT 
GCGGAGCAAG CCTTTTGGTG CCTGGTGCAG ATCTGCGACA AGTACCTCCC AGGTTACTAC 
AGTGCAGGGC TGGCGTTAAG ATCATCTTCC GGGTGGCCCT GGTCCTGCTG CGCCACACGC 
TGGGCTCAGT GGAGAAGCTG CGCTCCTGCC AAGGCATGTA TGAGACCATG GAGCAGCTGC 
GTAACCTGCC CCAGCAGTGC ATGCAGGAAG ACTTCCTGGT GCATGAGGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

All members of the EPI64 subfamily of TBC/RabGAPs also have GAP activities towards Ras.
Journal of biochemistry153(3)283-8(2013 Mar)
Nagai H,Yasuda S,Ohba Y,Fukuda M,Nakamura T

Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.
Molecular and cellular biology32(9)1733-44(2012 May)
Popovic D,Akutsu M,Novak I,Harper JW,Behrends C,Dikic I

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C.
The Journal of cell biology189(2)223-32(2010 Apr)
Hsu C,Morohashi Y,Yoshimura S,Manrique-Hoyos N,Jung S,Lauterbach MA,Bakhti M,Gr?nborg M,M?bius W,Rhee J,Barr FA,Simons M

Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.
Genes to cells : devoted to molecular & cellular mechanisms14(1)41-52(2009 Jan)
Ishibashi K,Kanno E,Itoh T,Fukuda M

Functional dissection of Rab GTPases involved in primary cilium formation.
The Journal of cell biology178(3)363-9(2007 Jul)
Yoshimura S,Egerer J,Fuchs E,Haas AK,Barr FA

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TBC1D10B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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FAX

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