MAFF cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAFF
Entrez Gene ID	23764
Full Name	MAF bZIP transcription factor F
Synonyms	U-MAF,hMafF
General protein information	Preferred Names MAF bZIP transcription factor F Names transcription factor MafF v-maf avian musculoaponeurotic fibrosarcoma oncogene family protein F v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q13.1
Summary	The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].
Disorder MIM:	604877

mRNA and Protein(s)

mRNA	Protein	Name
NM_001161574.1	NP_001155046.1	transcription factor MafF isoform b
NM_012323.3	NP_036455.1	transcription factor MafF isoform a
NM_001161572.1	NP_001155044.1	transcription factor MafF isoform a
NM_001161573.1	NP_001155045.1	transcription factor MafF isoform a
NM_012323.4	NP_036455.1	transcription factor MafF isoform a

Pathways from BioSystems

Homologies

Bos taurus (cattle)	MAFF	NP_001096770.1
Homo sapiens (human)	MAFF	NP_001155045.1
Canis lupus familiaris (dog)	MAFF	XP_005626274.1
Rattus norvegicus (Norway rat)	Maff	NP_001124045.1
Pan troglodytes (chimpanzee)	MAFF	XP_003317281.1
	MAFF	XP_001092874.1
Gallus gallus (chicken)	MAFF	NP_990088.1
Mus musculus (house mouse)	Maff	NP_034885.1

Gene Ontology
Bibliography

Related articles in PubMed

Small MAF genes variants and chronic myeloid leukemia.
Mart?nez-Hern?ndez A, Gutierrez-Malacatt H, Carrillo-S?nchez K, Salda?a-Alvarez Y, Rojas-Ochoa A, Crespo-Solis E, Aguayo-Gonz?lez A, Rosas-L?pez A, Ayala-Sanchez JM, Aquino-Ortega X, Orozco L, Cordova EJ
European journal of haematology92(1)35-41(2014 Jan)

DNA-binding specificities of human transcription factors.
Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J
Cell152(1-2)327-39(2013 Jan)

Establish a recombinant yeast detection system to study the effect of MIP on transactivation function of hMafF in US2-driven gene transcription.
Ye X, Shi Y, Huo K, Chen D
Journal of microbiological methods79(1)96-100(2009 Oct)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MAF genes have different levels of biological and genetic relevance. Besides, MAFF and MAFG could be associated with the susceptibility to develop CML.
Title: Small MAF genes variants and chronic myeloid leukemia.

Only in the presence of both MIP and hMafF could the nUS2-pLacZi reporter in yeast genome be activated.
Title: Establish a recombinant yeast detection system to study the effect of MIP on transactivation function of hMafF in US2-driven gene transcription.

Expression of hMafF or MIP alone did not alter basal reporter transcription activity, whereas co-expression of hMafF and MIP activated transcription efficiently.
Title: The novel human gene MIP functions as a co-activator of hMafF.

In myometrial cells we observed an important induction by interleukin 1 beta and a weaker upregulation by tumor necrosis factor, whereas interleukin 6 treatment had no effect.
Title: Regulation of the MAFF transcription factor by proinflammatory cytokines in myometrial cells.

MafF/NFE2 hetrodimers act as weak transcriptional activators, and, in particular, are able to stimulate activity of the GCS1 promoter.
Title: Cloning MafF by recognition site screening with the NFE2 tandem repeat of HS2: analysis of its role in globin and GCSl genes regulation.

The following MAFF gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAFF cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31535	NM_001161572.1 Latest version!	Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu31535	NM_001161573.1 Latest version!	Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu31535	NM_012323.4 Latest version!	Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu03210	NM_001161574.1 Latest version!	Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
View Old Accession Versions >>
OHu31535	NM_012323.3	Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAFF ( NM_012323.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036455.1 Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu31535
Clone ID Related Accession (Same CDS sequence)	NM_012323.3 , NM_001161572.1 , NM_001161573.1 , NM_012323.4
Accession Version	NM_012323.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	transcription factor MafF isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA209378.1, DA654696.1, AK002001.1, DB319587.1, AJ010857.1 and AI610651.1. On Jun 6, 2009 this sequence version replaced NM_012323.2. Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1, 3, and 4 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA209378.1, BC067751.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT 
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA 
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG 
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG 
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC 
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC 
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG 
GCCTCCTGCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036455.1
CDS	313..807
Translation	MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS

Target ORF information:

RefSeq Version	NM_012323.3
Organism	Homo sapiens(human)
Definition	Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012323.3

ORF Insert Sequence:

ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT 
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA 
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG 
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG 
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC 
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC 
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG 
GCCTCCTGCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAFF ( NM_001161572.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001155044.1 Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu31535
Clone ID Related Accession (Same CDS sequence)	NM_012323.3 , NM_001161572.1 , NM_001161573.1 , NM_012323.4
Accession Version	NM_001161572.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	transcription factor MafF isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA209378.1, DA654696.1, AK002001.1, DB319587.1, AJ010857.1 and AI610651.1. Transcript Variant: This variant (3) represents the longest transcript and encodes the longer isoform (a). Variants 1, 3, and 4 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA654696.1, DA501043.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093, SAMEA2149398 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT 
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA 
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG 
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG 
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC 
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC 
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG 
GCCTCCTGCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001155044.1
CDS	339..833
Translation	MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS

Target ORF information:

RefSeq Version	NM_001161572.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161572.1

ORF Insert Sequence:

ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT 
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA 
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG 
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG 
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC 
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC 
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG 
GCCTCCTGCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAFF ( NM_001161573.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001155045.1 Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu31535
Clone ID Related Accession (Same CDS sequence)	NM_012323.3 , NM_001161572.1 , NM_001161573.1 , NM_012323.4
Accession Version	NM_001161573.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	transcription factor MafF isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA425613.1, AK002001.1, DB319587.1, AJ010857.1 and AI610651.1. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 3. Variants 1, 3, and 4 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA425613.1, DA872919.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT 
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA 
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG 
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG 
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC 
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC 
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG 
GCCTCCTGCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001155045.1
CDS	97..591
Translation	MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS

Target ORF information:

RefSeq Version	NM_001161573.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161573.1

ORF Insert Sequence:

ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT 
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA 
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG 
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG 
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC 
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC 
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG 
GCCTCCTGCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAFF ( NM_012323.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_036455.1 Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu31535
Clone ID Related Accession (Same CDS sequence)	NM_012323.3 , NM_001161572.1 , NM_001161573.1 , NM_012323.4
Accession Version	NM_012323.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 495bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	transcription factor MafF isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA209378.1, DA654696.1, AK002001.1, DB319587.1, AJ010857.1 and AI610651.1. On Nov 23, 2018 this sequence version replaced NM_012323.3. Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1, 3, and 4 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC067751.1, AJ010857.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000338483.7/ ENSP00000345393.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT 
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA 
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG 
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG 
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC 
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC 
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG 
GCCTCCTGCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036455.1
CDS	251..745
Translation	MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS

Target ORF information:

RefSeq Version	NM_012323.4
Organism	Homo sapiens(human)
Definition	Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012323.4

ORF Insert Sequence:

ATGTCTGTGG ATCCCCTATC CAGCAAAGCT CTAAAGATCA AGCGAGAGCT GAGCGAGAAC 
ACGCCGCACC TGTCGGACGA GGCGCTGATG GGGCTGTCGG TGCGCGAGCT GAACCGGCAT 
CTGCGCGGGC TCTCCGCCGA GGAGGTGACA CGGCTCAAGC AGCGGCGCCG CACACTCAAA 
AACCGTGGCT ACGCCGCCAG CTGCCGCGTG AAGCGCGTGT GCCAGAAGGA GGAGCTGCAG 
AAGCAGAAGT CGGAGCTGGA GCGCGAGGTG GACAAGCTGG CGCGCGAGAA CGCCGCCATG 
CGCCTGGAGC TCGACGCGCT GCGCGGCAAG TGCGAGGCGC TGCAGGGCTT CGCGCGCTCC 
GTGGCCGCCG CCCGCGGGCC CGCCACGCTC GTGGCGCCGG CCAGCGTCAT CACCATCGTC 
AAGTCCACCC CGGGCTCGGG GTCTGGCCCC GCCCACGGCC CGGACCCCGC CCACGGCCCG 
GCCTCCTGCT CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAFF ( NM_001161574.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001155046.1 Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu03210
Clone ID Related Accession (Same CDS sequence)	NM_001161574.1
Accession Version	NM_001161574.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 408bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	transcription factor MafF isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA209378.1, AK300932.1, AK002001.1, DB319587.1, AJ010857.1 and AI610651.1. Transcript Variant: This variant (5) lacks the exon containing the translation start site compared to variant 3. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300932.1, DC388299.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02400288, SAMN02400289 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCTGT CGGTGCGCGA GCTGAACCGG CATCTGCGCG GGCTCTCCGC CGAGGAGGTG 
ACACGGCTCA AGCAGCGGCG CCGCACACTC AAAAACCGTG GCTACGCCGC CAGCTGCCGC 
GTGAAGCGCG TGTGCCAGAA GGAGGAGCTG CAGAAGCAGA AGTCGGAGCT GGAGCGCGAG 
GTGGACAAGC TGGCGCGCGA GAACGCCGCC ATGCGCCTGG AGCTCGACGC GCTGCGCGGC 
AAGTGCGAGG CGCTGCAGGG CTTCGCGCGC TCCGTGGCCG CCGCCCGCGG GCCCGCCACG 
CTCGTGGCGC CGGCCAGCGT CATCACCATC GTCAAGTCCA CCCCGGGCTC GGGGTCTGGC 
CCCGCCCACG GCCCGGACCC CGCCCACGGC CCGGCCTCCT GCTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001155046.1
CDS	333..740
Translation	MGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS

Target ORF information:

RefSeq Version	NM_001161574.1
Organism	Homo sapiens(human)
Definition	Homo sapiens MAF bZIP transcription factor F (MAFF), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001161574.1

ORF Insert Sequence:

ATGGGGCTGT CGGTGCGCGA GCTGAACCGG CATCTGCGCG GGCTCTCCGC CGAGGAGGTG 
ACACGGCTCA AGCAGCGGCG CCGCACACTC AAAAACCGTG GCTACGCCGC CAGCTGCCGC 
GTGAAGCGCG TGTGCCAGAA GGAGGAGCTG CAGAAGCAGA AGTCGGAGCT GGAGCGCGAG 
GTGGACAAGC TGGCGCGCGA GAACGCCGCC ATGCGCCTGG AGCTCGACGC GCTGCGCGGC 
AAGTGCGAGG CGCTGCAGGG CTTCGCGCGC TCCGTGGCCG CCGCCCGCGG GCCCGCCACG 
CTCGTGGCGC CGGCCAGCGT CATCACCATC GTCAAGTCCA CCCCGGGCTC GGGGTCTGGC 
CCCGCCCACG GCCCGGACCC CGCCCACGGC CCGGCCTCCT GCTCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Small MAF genes variants and chronic myeloid leukemia.
European journal of haematology92(1)35-41(2014 Jan)
Mart?nez-Hern?ndez A,Gutierrez-Malacatt H,Carrillo-S?nchez K,Salda?a-Alvarez Y,Rojas-Ochoa A,Crespo-Solis E,Aguayo-Gonz?lez A,Rosas-L?pez A,Ayala-Sanchez JM,Aquino-Ortega X,Orozco L,Cordova EJ

DNA-binding specificities of human transcription factors.
Cell152(1-2)327-39(2013 Jan)
Jolma A,Yan J,Whitington T,Toivonen J,Nitta KR,Rastas P,Morgunova E,Enge M,Taipale M,Wei G,Palin K,Vaquerizas JM,Vincentelli R,Luscombe NM,Hughes TR,Lemaire P,Ukkonen E,Kivioja T,Taipale J

Establish a recombinant yeast detection system to study the effect of MIP on transactivation function of hMafF in US2-driven gene transcription.
Journal of microbiological methods79(1)96-100(2009 Oct)
Ye X,Shi Y,Huo K,Chen D

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM

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MAFF cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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