NCDN cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NCDN
Entrez Gene ID	23154
Full Name	neurochondrin
General protein information	Preferred Names neurochondrin Names neurochondrin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p34.3
Summary	This gene encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be essential for spatial learning processes. Several alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jul 2008].
Disorder MIM:	608458

mRNA and Protein(s)

mRNA	Protein	Name
NM_001014839.1	NP_001014839.1	neurochondrin isoform 1
NM_014284.2	NP_055099.1	neurochondrin isoform 1
NM_014284.3	NP_055099.1	neurochondrin isoform 1
NM_001014841.1	NP_001014841.1	neurochondrin isoform 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	NCDN	XP_532565.2
Pan troglodytes (chimpanzee)	NCDN	XP_003308021.1
	NCDN	XP_002802364.1
Xenopus tropicalis (tropical clawed frog)	ncdn	XP_002938879.1
Homo sapiens (human)	NCDN	NP_001014839.1
Gallus gallus (chicken)	NCDN	NP_001026072.1
Danio rerio (zebrafish)	ncdn	XP_002667129.1
Drosophila melanogaster (fruit fly)	Neurochondrin	NP_649658.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP013338	XP_003436800.1
Rattus norvegicus (Norway rat)	Ncdn	NP_445995.2
Bos taurus (cattle)	NCDN	NP_001039396.1
Mus musculus (house mouse)	Ncdn	NP_036116.3

Gene Ontology
Bibliography

Related articles in PubMed

Altered Norbin Expression in Patients with Epilepsy and a Rat Model.
Xu Y, Li Z, Yao L, Zhang X, Gan D, Jiang M, Wang N, Chen G, Wang X
Scientific reports7(1)13970(2017 Oct)

Neurochondrin is an atypical RII?-specific A-kinase anchoring protein.
Hermann JS, Skroblin P, Bertinetti D, Hanold LE, von der Heide EK, Wagener EM, Zenn HM, Klussmann E, Kennedy EJ, Herberg FW
Biochimica et biophysica acta1854(10 Pt B)1667-75(2015 Oct)

Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia.
Matosin N, Fernandez-Enright F, Lum JS, Andrews JL, Engel M, Huang XF, Newell KA
Schizophrenia research166(1-3)212-8(2015 Aug)

In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes.
Oku S, Takahashi N, Fukata Y, Fukata M
The Journal of biological chemistry288(27)19816-29(2013 Jul)

Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
Martins-de-Souza D, Guest PC, Mann DM, Roeber S, Rahmoune H, Bauder C, Kretzschmar H, Volk B, Baborie A, Bahn S
Journal of proteome research11(4)2533-43(2012 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we demonstrate that neurochondrin has strong isoform selectivity towards the RIIa subunit of PKA with nanomolar affinity
Title: Neurochondrin is an atypical RII?-specific A-kinase anchoring protein.

Schizophrenia subjects compared to controls showed a marked increase in CA1 hippocampal Norbin, and Tamalin proteins (47% and 34% respectively), which are endogenous regulators of mGluR5 signalling and trafficking
Title: Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia.

In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes.
Title: In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes.

A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.
Title: Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.

In mouse, the encoded protein is a negative regulator of Ca/calmodulin-dependent protein kinase II phosphorylation and is essential for the spatial learning process.
Title: Neurochondrin negatively regulates CaMKII phosphorylation, and nervous system-specific gene disruption results in epileptic seizure.

The following NCDN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NCDN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04160	NM_014284.3 Latest version!	Homo sapiens neurochondrin (NCDN), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu04160	NM_001014839.1 Latest version!	Homo sapiens neurochondrin (NCDN), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu29542	NM_001014841.1 Latest version!	Homo sapiens neurochondrin (NCDN), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu04160	NM_014284.2	Homo sapiens neurochondrin (NCDN), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NCDN ( NM_001014839.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001014839.1 Homo sapiens neurochondrin (NCDN), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04160
Clone ID Related Accession (Same CDS sequence)	NM_001014839.1 , NM_014284.2 , NM_014284.3
Accession Version	NM_001014839.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2190bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Homo sapiens(human)
Product	neurochondrin isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL536768.3, AB018739.2, BC024592.1 and AW207151.1. Transcript Variant: This variant (1), also known as NCDN-1, encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.111567.1, AB018739.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGTGTT GTGACCTGGC TGCGGCGGGA CAGTTGGGCA AGGCGAGCAT CATGGCCTCG 
GATTGCGAGC CAGCTCTGAA CCAGGCAGAG GGCCGAAACC CCACCCTGGA GCGCTACCTG 
GGAGCCCTCC GTGAGGCCAA GAATGACAGC GAGCAGTTTG CAGCCCTGCT GCTAGTGACC 
AAGGCAGTCA AAGCAGGTGA CATAGATGCC AAAACTCGGC GGCGGATCTT CGATGCTGTC 
GGCTTCACCT TCCCCAATCG TCTCCTGACC ACCAAGGAGG CGCCGGATGG CTGCCCTGAC 
CATGTTCTGC GGGCTTTGGG TGTGGCCCTG CTGGCCTGCT TCTGCAGTGA CCCTGAACTG 
GCCGCCCATC CCCAAGTCCT GAACAAGATT CCCATTCTTA GCACCTTCCT CACAGCCCGG 
GGGGACCCGG ACGATGCTGC CCGCCGCTCC ATGATTGATG ACACCTACCA GTGCCTGACG 
GCTGTAGCAG GCACACCCAG AGGGCCTCGG CACCTCATTG CTGGTGGCAC CGTGTCTGCC 
CTATGCCAGG CATACCTGGG GCACGGCTAT GGCTTTGACC AGGCCCTGGC ACTCCTGGTG 
GGGCTGCTGG CTGCTGCCGA GACACAGTGC TGGAAGGAGG CGGAGCCCGA CCTGCTGGCC 
GTGTTGCGGG GCCTCAGTGA GGATTTCCAG AAAGCTGAGG ATGCCAGCAA GTTTGAGCTC 
TGCCAGCTGC TGCCCCTCTT TTTGCCCCCG ACAACCGTGC CCCCTGAATG CTACCGGGAT 
CTGCAGGCCG GGCTGGCACG CATCCTGGGA AGCAAGCTGA GCTCCTGGCA GCGCAACCCT 
GCACTGAAGC TGGCAGCCCG CCTGGCACAC GCCTGCGGCT CCGACTGGAT CCCGGCGGGC 
AGCTCCGGGA GCAAGTTCCT GGCCCTGCTG GTGAATCTGG CGTGCGTGGA AGTGCGGCTG 
GCACTGGAGG AGACGGGCAC GGAGGTGAAA GAGGATGTGG TGACCGCCTG CTATGCCCTC 
ATGGAGTTGG GGATCCAGGA ATGCACTCGC TGTGAGCAGT CACTGCTTAA GGAGCCACAG 
AAGGTGCAGC TCGTGAGCGT CATGAAGGAG GCCATAGGGG CTGTTATCCA CTACCTGCTG 
CAGGTGGGGT CAGAGAAGCA GAAGGAGCCC TTTGTGTTTG CCTCGGTGCG GATCCTGGGT 
GCCTGGCTGG CCGAGGAGAC CTCATCCTTG CGTAAGGAGG TGTGCCAGCT GCTGCCCTTC 
CTCGTCCGCT ATGCCAAGAC CCTCTACGAG GAGGCCGAGG AGGCCAATGA CCTTTCCCAG 
CAGGTGGCCA ACCTGGCCAT CTCCCCCACC ACCCCAGGGC CCACCTGGCC AGGAGACGCT 
CTCCGGCTCC TCCTGCCTGG CTGGTGCCAC CTGACCGTTG AAGATGGGCC CCGGGAGATC 
CTGATCAAGG AAGGGGCCCC CTCGCTTCTG TGCAAGTATT TCCTGCAGCA GTGGGAACTC 
ACATCCCCTG GCCACGACAC CTCGGTGCTG CCTGACAGCG TGGAGATTGG CCTGCAGACC 
TGCTGCCACA TCTTCCTCAA CCTCGTGGTC ACCGCACCGG GGCTGATCAA GCGTGACGCC 
TGCTTCACAT CTCTAATGAA CACCCTCATG ACGTCGCTAC CAGCACTAGT GCAGCAACAG 
GGAAGGCTGC TTCTGGCTGC TAATGTGGCC ACCCTGGGGC TCCTCATGGC CCGGCTCCTT 
AGCACCTCTC CAGCTCTTCA GGGAACACCA GCATCCCGAG GGTTCTTCGC AGCTGCCATC 
CTCTTCCTAT CACAGTCCCA CGTGGCGCGG GCCACCCCGG GCTCAGACCA GGCAGTGCTA 
GCCCTGTCCC CTGAGTATGA GGGCATCTGG GCCGACCTGC AGGAGCTCTG GTTCCTGGGC 
ATGCAGGCCT TCACCGGCTG TGTGCCTCTG CTGCCCTGGC TGGCCCCCGC TGCCCTGCGC 
TCCCGCTGGC CGCAGGAGCT GCTCCAGCTG CTAGGCAGTG TCAGCCCCAA CTCTGTCAAG 
CCCGAGATGG TGGCCGCCTA TCAGGGTGTC CTGGTGGAGC TGGCGCGGGC CAACCGGCTG 
TGCCGGGAGG CCATGAGGCT GCAGGCGGGC GAGGAGACGG CCAGCCACTA CCGCATGGCT 
GCCTTGGAGC AGTGCCTGTC AGAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014839.1
CDS	128..2317
Translation	MSCCDLAAAGQLGKASIMASDCEPALNQAEGRNPTLERYLGALREAKNDSEQFAALLLVTKAVKAGDIDAKTRRRIFDAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPELAAHPQVLNKIPILSTFLTARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSALCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQKAEDASKFELCQLLPLFLPPTTVPPECYRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPAGSSGSKFLALLVNLACVEVRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQKVQLVSVMKEAIGAVIHYLLQVGSEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPFLVRYAKTLYEEAEEANDLSQQVANLAISPTTPGPTWPGDALRLLLPGWCHLTVEDGPREILIKEGAPSLLCKYFLQQWELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDACFTSLMNTLMTSLPALVQQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAILFLSQSHVARATPGSDQAVLALSPEYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALRSRWPQELLQLLGSVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMAALEQCLSEP

Target ORF information:

RefSeq Version	NM_001014839.1
Organism	Homo sapiens(human)
Definition	Homo sapiens neurochondrin (NCDN), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014839.1

ORF Insert Sequence:

ATGTCGTGTT GTGACCTGGC TGCGGCGGGA CAGTTGGGCA AGGCGAGCAT CATGGCCTCG 
GATTGCGAGC CAGCTCTGAA CCAGGCAGAG GGCCGAAACC CCACCCTGGA GCGCTACCTG 
GGAGCCCTCC GTGAGGCCAA GAATGACAGC GAGCAGTTTG CAGCCCTGCT GCTAGTGACC 
AAGGCAGTCA AAGCAGGTGA CATAGATGCC AAAACTCGGC GGCGGATCTT CGATGCTGTC 
GGCTTCACCT TCCCCAATCG TCTCCTGACC ACCAAGGAGG CGCCGGATGG CTGCCCTGAC 
CATGTTCTGC GGGCTTTGGG TGTGGCCCTG CTGGCCTGCT TCTGCAGTGA CCCTGAACTG 
GCCGCCCATC CCCAAGTCCT GAACAAGATT CCCATTCTTA GCACCTTCCT CACAGCCCGG 
GGGGACCCGG ACGATGCTGC CCGCCGCTCC ATGATTGATG ACACCTACCA GTGCCTGACG 
GCTGTAGCAG GCACACCCAG AGGGCCTCGG CACCTCATTG CTGGTGGCAC CGTGTCTGCC 
CTATGCCAGG CATACCTGGG GCACGGCTAT GGCTTTGACC AGGCCCTGGC ACTCCTGGTG 
GGGCTGCTGG CTGCTGCCGA GACACAGTGC TGGAAGGAGG CGGAGCCCGA CCTGCTGGCC 
GTGTTGCGGG GCCTCAGTGA GGATTTCCAG AAAGCTGAGG ATGCCAGCAA GTTTGAGCTC 
TGCCAGCTGC TGCCCCTCTT TTTGCCCCCG ACAACCGTGC CCCCTGAATG CTACCGGGAT 
CTGCAGGCCG GGCTGGCACG CATCCTGGGA AGCAAGCTGA GCTCCTGGCA GCGCAACCCT 
GCACTGAAGC TGGCAGCCCG CCTGGCACAC GCCTGCGGCT CCGACTGGAT CCCGGCGGGC 
AGCTCCGGGA GCAAGTTCCT GGCCCTGCTG GTGAATCTGG CGTGCGTGGA AGTGCGGCTG 
GCACTGGAGG AGACGGGCAC GGAGGTGAAA GAGGATGTGG TGACCGCCTG CTATGCCCTC 
ATGGAGTTGG GGATCCAGGA ATGCACTCGC TGTGAGCAGT CACTGCTTAA GGAGCCACAG 
AAGGTGCAGC TCGTGAGCGT CATGAAGGAG GCCATAGGGG CTGTTATCCA CTACCTGCTG 
CAGGTGGGGT CAGAGAAGCA GAAGGAGCCC TTTGTGTTTG CCTCGGTGCG GATCCTGGGT 
GCCTGGCTGG CCGAGGAGAC CTCATCCTTG CGTAAGGAGG TGTGCCAGCT GCTGCCCTTC 
CTCGTCCGCT ATGCCAAGAC CCTCTACGAG GAGGCCGAGG AGGCCAATGA CCTTTCCCAG 
CAGGTGGCCA ACCTGGCCAT CTCCCCCACC ACCCCAGGGC CCACCTGGCC AGGAGACGCT 
CTCCGGCTCC TCCTGCCTGG CTGGTGCCAC CTGACCGTTG AAGATGGGCC CCGGGAGATC 
CTGATCAAGG AAGGGGCCCC CTCGCTTCTG TGCAAGTATT TCCTGCAGCA GTGGGAACTC 
ACATCCCCTG GCCACGACAC CTCGGTGCTG CCTGACAGCG TGGAGATTGG CCTGCAGACC 
TGCTGCCACA TCTTCCTCAA CCTCGTGGTC ACCGCACCGG GGCTGATCAA GCGTGACGCC 
TGCTTCACAT CTCTAATGAA CACCCTCATG ACGTCGCTAC CAGCACTAGT GCAGCAACAG 
GGAAGGCTGC TTCTGGCTGC TAATGTGGCC ACCCTGGGGC TCCTCATGGC CCGGCTCCTT 
AGCACCTCTC CAGCTCTTCA GGGAACACCA GCATCCCGAG GGTTCTTCGC AGCTGCCATC 
CTCTTCCTAT CACAGTCCCA CGTGGCGCGG GCCACCCCGG GCTCAGACCA GGCAGTGCTA 
GCCCTGTCCC CTGAGTATGA GGGCATCTGG GCCGACCTGC AGGAGCTCTG GTTCCTGGGC 
ATGCAGGCCT TCACCGGCTG TGTGCCTCTG CTGCCCTGGC TGGCCCCCGC TGCCCTGCGC 
TCCCGCTGGC CGCAGGAGCT GCTCCAGCTG CTAGGCAGTG TCAGCCCCAA CTCTGTCAAG 
CCCGAGATGG TGGCCGCCTA TCAGGGTGTC CTGGTGGAGC TGGCGCGGGC CAACCGGCTG 
TGCCGGGAGG CCATGAGGCT GCAGGCGGGC GAGGAGACGG CCAGCCACTA CCGCATGGCT 
GCCTTGGAGC AGTGCCTGTC AGAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCDN ( NM_014284.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055099.1 Homo sapiens neurochondrin (NCDN), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu04160
Clone ID Related Accession (Same CDS sequence)	NM_001014839.1 , NM_014284.2 , NM_014284.3
Accession Version	NM_014284.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2190bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	neurochondrin isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL536768.3, BC024592.1, BI545092.1 and AW207151.1. On Apr 12, 2005 this sequence version replaced NM_014284.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 and 3 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC024592.1, SRR1660803.102306.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGTGTT GTGACCTGGC TGCGGCGGGA CAGTTGGGCA AGGCGAGCAT CATGGCCTCG 
GATTGCGAGC CAGCTCTGAA CCAGGCAGAG GGCCGAAACC CCACCCTGGA GCGCTACCTG 
GGAGCCCTCC GTGAGGCCAA GAATGACAGC GAGCAGTTTG CAGCCCTGCT GCTAGTGACC 
AAGGCAGTCA AAGCAGGTGA CATAGATGCC AAAACTCGGC GGCGGATCTT CGATGCTGTC 
GGCTTCACCT TCCCCAATCG TCTCCTGACC ACCAAGGAGG CGCCGGATGG CTGCCCTGAC 
CATGTTCTGC GGGCTTTGGG TGTGGCCCTG CTGGCCTGCT TCTGCAGTGA CCCTGAACTG 
GCCGCCCATC CCCAAGTCCT GAACAAGATT CCCATTCTTA GCACCTTCCT CACAGCCCGG 
GGGGACCCGG ACGATGCTGC CCGCCGCTCC ATGATTGATG ACACCTACCA GTGCCTGACG 
GCTGTAGCAG GCACACCCAG AGGGCCTCGG CACCTCATTG CTGGTGGCAC CGTGTCTGCC 
CTATGCCAGG CATACCTGGG GCACGGCTAT GGCTTTGACC AGGCCCTGGC ACTCCTGGTG 
GGGCTGCTGG CTGCTGCCGA GACACAGTGC TGGAAGGAGG CGGAGCCCGA CCTGCTGGCC 
GTGTTGCGGG GCCTCAGTGA GGATTTCCAG AAAGCTGAGG ATGCCAGCAA GTTTGAGCTC 
TGCCAGCTGC TGCCCCTCTT TTTGCCCCCG ACAACCGTGC CCCCTGAATG CTACCGGGAT 
CTGCAGGCCG GGCTGGCACG CATCCTGGGA AGCAAGCTGA GCTCCTGGCA GCGCAACCCT 
GCACTGAAGC TGGCAGCCCG CCTGGCACAC GCCTGCGGCT CCGACTGGAT CCCGGCGGGC 
AGCTCCGGGA GCAAGTTCCT GGCCCTGCTG GTGAATCTGG CGTGCGTGGA AGTGCGGCTG 
GCACTGGAGG AGACGGGCAC GGAGGTGAAA GAGGATGTGG TGACCGCCTG CTATGCCCTC 
ATGGAGTTGG GGATCCAGGA ATGCACTCGC TGTGAGCAGT CACTGCTTAA GGAGCCACAG 
AAGGTGCAGC TCGTGAGCGT CATGAAGGAG GCCATAGGGG CTGTTATCCA CTACCTGCTG 
CAGGTGGGGT CAGAGAAGCA GAAGGAGCCC TTTGTGTTTG CCTCGGTGCG GATCCTGGGT 
GCCTGGCTGG CCGAGGAGAC CTCATCCTTG CGTAAGGAGG TGTGCCAGCT GCTGCCCTTC 
CTCGTCCGCT ATGCCAAGAC CCTCTACGAG GAGGCCGAGG AGGCCAATGA CCTTTCCCAG 
CAGGTGGCCA ACCTGGCCAT CTCCCCCACC ACCCCAGGGC CCACCTGGCC AGGAGACGCT 
CTCCGGCTCC TCCTGCCTGG CTGGTGCCAC CTGACCGTTG AAGATGGGCC CCGGGAGATC 
CTGATCAAGG AAGGGGCCCC CTCGCTTCTG TGCAAGTATT TCCTGCAGCA GTGGGAACTC 
ACATCCCCTG GCCACGACAC CTCGGTGCTG CCTGACAGCG TGGAGATTGG CCTGCAGACC 
TGCTGCCACA TCTTCCTCAA CCTCGTGGTC ACCGCACCGG GGCTGATCAA GCGTGACGCC 
TGCTTCACAT CTCTAATGAA CACCCTCATG ACGTCGCTAC CAGCACTAGT GCAGCAACAG 
GGAAGGCTGC TTCTGGCTGC TAATGTGGCC ACCCTGGGGC TCCTCATGGC CCGGCTCCTT 
AGCACCTCTC CAGCTCTTCA GGGAACACCA GCATCCCGAG GGTTCTTCGC AGCTGCCATC 
CTCTTCCTAT CACAGTCCCA CGTGGCGCGG GCCACCCCGG GCTCAGACCA GGCAGTGCTA 
GCCCTGTCCC CTGAGTATGA GGGCATCTGG GCCGACCTGC AGGAGCTCTG GTTCCTGGGC 
ATGCAGGCCT TCACCGGCTG TGTGCCTCTG CTGCCCTGGC TGGCCCCCGC TGCCCTGCGC 
TCCCGCTGGC CGCAGGAGCT GCTCCAGCTG CTAGGCAGTG TCAGCCCCAA CTCTGTCAAG 
CCCGAGATGG TGGCCGCCTA TCAGGGTGTC CTGGTGGAGC TGGCGCGGGC CAACCGGCTG 
TGCCGGGAGG CCATGAGGCT GCAGGCGGGC GAGGAGACGG CCAGCCACTA CCGCATGGCT 
GCCTTGGAGC AGTGCCTGTC AGAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055099.1
CDS	400..2589
Translation	MSCCDLAAAGQLGKASIMASDCEPALNQAEGRNPTLERYLGALREAKNDSEQFAALLLVTKAVKAGDIDAKTRRRIFDAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPELAAHPQVLNKIPILSTFLTARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSALCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQKAEDASKFELCQLLPLFLPPTTVPPECYRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPAGSSGSKFLALLVNLACVEVRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQKVQLVSVMKEAIGAVIHYLLQVGSEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPFLVRYAKTLYEEAEEANDLSQQVANLAISPTTPGPTWPGDALRLLLPGWCHLTVEDGPREILIKEGAPSLLCKYFLQQWELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDACFTSLMNTLMTSLPALVQQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAILFLSQSHVARATPGSDQAVLALSPEYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALRSRWPQELLQLLGSVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMAALEQCLSEP

Target ORF information:

RefSeq Version	NM_014284.2
Organism	Homo sapiens(human)
Definition	Homo sapiens neurochondrin (NCDN), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014284.2

ORF Insert Sequence:

ATGTCGTGTT GTGACCTGGC TGCGGCGGGA CAGTTGGGCA AGGCGAGCAT CATGGCCTCG 
GATTGCGAGC CAGCTCTGAA CCAGGCAGAG GGCCGAAACC CCACCCTGGA GCGCTACCTG 
GGAGCCCTCC GTGAGGCCAA GAATGACAGC GAGCAGTTTG CAGCCCTGCT GCTAGTGACC 
AAGGCAGTCA AAGCAGGTGA CATAGATGCC AAAACTCGGC GGCGGATCTT CGATGCTGTC 
GGCTTCACCT TCCCCAATCG TCTCCTGACC ACCAAGGAGG CGCCGGATGG CTGCCCTGAC 
CATGTTCTGC GGGCTTTGGG TGTGGCCCTG CTGGCCTGCT TCTGCAGTGA CCCTGAACTG 
GCCGCCCATC CCCAAGTCCT GAACAAGATT CCCATTCTTA GCACCTTCCT CACAGCCCGG 
GGGGACCCGG ACGATGCTGC CCGCCGCTCC ATGATTGATG ACACCTACCA GTGCCTGACG 
GCTGTAGCAG GCACACCCAG AGGGCCTCGG CACCTCATTG CTGGTGGCAC CGTGTCTGCC 
CTATGCCAGG CATACCTGGG GCACGGCTAT GGCTTTGACC AGGCCCTGGC ACTCCTGGTG 
GGGCTGCTGG CTGCTGCCGA GACACAGTGC TGGAAGGAGG CGGAGCCCGA CCTGCTGGCC 
GTGTTGCGGG GCCTCAGTGA GGATTTCCAG AAAGCTGAGG ATGCCAGCAA GTTTGAGCTC 
TGCCAGCTGC TGCCCCTCTT TTTGCCCCCG ACAACCGTGC CCCCTGAATG CTACCGGGAT 
CTGCAGGCCG GGCTGGCACG CATCCTGGGA AGCAAGCTGA GCTCCTGGCA GCGCAACCCT 
GCACTGAAGC TGGCAGCCCG CCTGGCACAC GCCTGCGGCT CCGACTGGAT CCCGGCGGGC 
AGCTCCGGGA GCAAGTTCCT GGCCCTGCTG GTGAATCTGG CGTGCGTGGA AGTGCGGCTG 
GCACTGGAGG AGACGGGCAC GGAGGTGAAA GAGGATGTGG TGACCGCCTG CTATGCCCTC 
ATGGAGTTGG GGATCCAGGA ATGCACTCGC TGTGAGCAGT CACTGCTTAA GGAGCCACAG 
AAGGTGCAGC TCGTGAGCGT CATGAAGGAG GCCATAGGGG CTGTTATCCA CTACCTGCTG 
CAGGTGGGGT CAGAGAAGCA GAAGGAGCCC TTTGTGTTTG CCTCGGTGCG GATCCTGGGT 
GCCTGGCTGG CCGAGGAGAC CTCATCCTTG CGTAAGGAGG TGTGCCAGCT GCTGCCCTTC 
CTCGTCCGCT ATGCCAAGAC CCTCTACGAG GAGGCCGAGG AGGCCAATGA CCTTTCCCAG 
CAGGTGGCCA ACCTGGCCAT CTCCCCCACC ACCCCAGGGC CCACCTGGCC AGGAGACGCT 
CTCCGGCTCC TCCTGCCTGG CTGGTGCCAC CTGACCGTTG AAGATGGGCC CCGGGAGATC 
CTGATCAAGG AAGGGGCCCC CTCGCTTCTG TGCAAGTATT TCCTGCAGCA GTGGGAACTC 
ACATCCCCTG GCCACGACAC CTCGGTGCTG CCTGACAGCG TGGAGATTGG CCTGCAGACC 
TGCTGCCACA TCTTCCTCAA CCTCGTGGTC ACCGCACCGG GGCTGATCAA GCGTGACGCC 
TGCTTCACAT CTCTAATGAA CACCCTCATG ACGTCGCTAC CAGCACTAGT GCAGCAACAG 
GGAAGGCTGC TTCTGGCTGC TAATGTGGCC ACCCTGGGGC TCCTCATGGC CCGGCTCCTT 
AGCACCTCTC CAGCTCTTCA GGGAACACCA GCATCCCGAG GGTTCTTCGC AGCTGCCATC 
CTCTTCCTAT CACAGTCCCA CGTGGCGCGG GCCACCCCGG GCTCAGACCA GGCAGTGCTA 
GCCCTGTCCC CTGAGTATGA GGGCATCTGG GCCGACCTGC AGGAGCTCTG GTTCCTGGGC 
ATGCAGGCCT TCACCGGCTG TGTGCCTCTG CTGCCCTGGC TGGCCCCCGC TGCCCTGCGC 
TCCCGCTGGC CGCAGGAGCT GCTCCAGCTG CTAGGCAGTG TCAGCCCCAA CTCTGTCAAG 
CCCGAGATGG TGGCCGCCTA TCAGGGTGTC CTGGTGGAGC TGGCGCGGGC CAACCGGCTG 
TGCCGGGAGG CCATGAGGCT GCAGGCGGGC GAGGAGACGG CCAGCCACTA CCGCATGGCT 
GCCTTGGAGC AGTGCCTGTC AGAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCDN ( NM_014284.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055099.1 Homo sapiens neurochondrin (NCDN), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu04160
Clone ID Related Accession (Same CDS sequence)	NM_001014839.1 , NM_014284.2 , NM_014284.3
Accession Version	NM_014284.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2190bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	neurochondrin isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL536768.3, BC024592.1, BI545092.1 and AW207151.1. On Nov 22, 2018 this sequence version replaced NM_014284.2. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 and 3 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC024592.1, SRR3476690.841529.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000373243.7/ ENSP00000362340.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGTGTT GTGACCTGGC TGCGGCGGGA CAGTTGGGCA AGGCGAGCAT CATGGCCTCG 
GATTGCGAGC CAGCTCTGAA CCAGGCAGAG GGCCGAAACC CCACCCTGGA GCGCTACCTG 
GGAGCCCTCC GTGAGGCCAA GAATGACAGC GAGCAGTTTG CAGCCCTGCT GCTAGTGACC 
AAGGCAGTCA AAGCAGGTGA CATAGATGCC AAAACTCGGC GGCGGATCTT CGATGCTGTC 
GGCTTCACCT TCCCCAATCG TCTCCTGACC ACCAAGGAGG CGCCGGATGG CTGCCCTGAC 
CATGTTCTGC GGGCTTTGGG TGTGGCCCTG CTGGCCTGCT TCTGCAGTGA CCCTGAACTG 
GCCGCCCATC CCCAAGTCCT GAACAAGATT CCCATTCTTA GCACCTTCCT CACAGCCCGG 
GGGGACCCGG ACGATGCTGC CCGCCGCTCC ATGATTGATG ACACCTACCA GTGCCTGACG 
GCTGTAGCAG GCACACCCAG AGGGCCTCGG CACCTCATTG CTGGTGGCAC CGTGTCTGCC 
CTATGCCAGG CATACCTGGG GCACGGCTAT GGCTTTGACC AGGCCCTGGC ACTCCTGGTG 
GGGCTGCTGG CTGCTGCCGA GACACAGTGC TGGAAGGAGG CGGAGCCCGA CCTGCTGGCC 
GTGTTGCGGG GCCTCAGTGA GGATTTCCAG AAAGCTGAGG ATGCCAGCAA GTTTGAGCTC 
TGCCAGCTGC TGCCCCTCTT TTTGCCCCCG ACAACCGTGC CCCCTGAATG CTACCGGGAT 
CTGCAGGCCG GGCTGGCACG CATCCTGGGA AGCAAGCTGA GCTCCTGGCA GCGCAACCCT 
GCACTGAAGC TGGCAGCCCG CCTGGCACAC GCCTGCGGCT CCGACTGGAT CCCGGCGGGC 
AGCTCCGGGA GCAAGTTCCT GGCCCTGCTG GTGAATCTGG CGTGCGTGGA AGTGCGGCTG 
GCACTGGAGG AGACGGGCAC GGAGGTGAAA GAGGATGTGG TGACCGCCTG CTATGCCCTC 
ATGGAGTTGG GGATCCAGGA ATGCACTCGC TGTGAGCAGT CACTGCTTAA GGAGCCACAG 
AAGGTGCAGC TCGTGAGCGT CATGAAGGAG GCCATAGGGG CTGTTATCCA CTACCTGCTG 
CAGGTGGGGT CAGAGAAGCA GAAGGAGCCC TTTGTGTTTG CCTCGGTGCG GATCCTGGGT 
GCCTGGCTGG CCGAGGAGAC CTCATCCTTG CGTAAGGAGG TGTGCCAGCT GCTGCCCTTC 
CTCGTCCGCT ATGCCAAGAC CCTCTACGAG GAGGCCGAGG AGGCCAATGA CCTTTCCCAG 
CAGGTGGCCA ACCTGGCCAT CTCCCCCACC ACCCCAGGGC CCACCTGGCC AGGAGACGCT 
CTCCGGCTCC TCCTGCCTGG CTGGTGCCAC CTGACCGTTG AAGATGGGCC CCGGGAGATC 
CTGATCAAGG AAGGGGCCCC CTCGCTTCTG TGCAAGTATT TCCTGCAGCA GTGGGAACTC 
ACATCCCCTG GCCACGACAC CTCGGTGCTG CCTGACAGCG TGGAGATTGG CCTGCAGACC 
TGCTGCCACA TCTTCCTCAA CCTCGTGGTC ACCGCACCGG GGCTGATCAA GCGTGACGCC 
TGCTTCACAT CTCTAATGAA CACCCTCATG ACGTCGCTAC CAGCACTAGT GCAGCAACAG 
GGAAGGCTGC TTCTGGCTGC TAATGTGGCC ACCCTGGGGC TCCTCATGGC CCGGCTCCTT 
AGCACCTCTC CAGCTCTTCA GGGAACACCA GCATCCCGAG GGTTCTTCGC AGCTGCCATC 
CTCTTCCTAT CACAGTCCCA CGTGGCGCGG GCCACCCCGG GCTCAGACCA GGCAGTGCTA 
GCCCTGTCCC CTGAGTATGA GGGCATCTGG GCCGACCTGC AGGAGCTCTG GTTCCTGGGC 
ATGCAGGCCT TCACCGGCTG TGTGCCTCTG CTGCCCTGGC TGGCCCCCGC TGCCCTGCGC 
TCCCGCTGGC CGCAGGAGCT GCTCCAGCTG CTAGGCAGTG TCAGCCCCAA CTCTGTCAAG 
CCCGAGATGG TGGCCGCCTA TCAGGGTGTC CTGGTGGAGC TGGCGCGGGC CAACCGGCTG 
TGCCGGGAGG CCATGAGGCT GCAGGCGGGC GAGGAGACGG CCAGCCACTA CCGCATGGCT 
GCCTTGGAGC AGTGCCTGTC AGAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055099.1
CDS	393..2582
Translation	MSCCDLAAAGQLGKASIMASDCEPALNQAEGRNPTLERYLGALREAKNDSEQFAALLLVTKAVKAGDIDAKTRRRIFDAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPELAAHPQVLNKIPILSTFLTARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSALCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQKAEDASKFELCQLLPLFLPPTTVPPECYRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPAGSSGSKFLALLVNLACVEVRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQKVQLVSVMKEAIGAVIHYLLQVGSEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPFLVRYAKTLYEEAEEANDLSQQVANLAISPTTPGPTWPGDALRLLLPGWCHLTVEDGPREILIKEGAPSLLCKYFLQQWELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDACFTSLMNTLMTSLPALVQQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAILFLSQSHVARATPGSDQAVLALSPEYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALRSRWPQELLQLLGSVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMAALEQCLSEP

Target ORF information:

RefSeq Version	NM_014284.3
Organism	Homo sapiens(human)
Definition	Homo sapiens neurochondrin (NCDN), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014284.3

ORF Insert Sequence:

ATGTCGTGTT GTGACCTGGC TGCGGCGGGA CAGTTGGGCA AGGCGAGCAT CATGGCCTCG 
GATTGCGAGC CAGCTCTGAA CCAGGCAGAG GGCCGAAACC CCACCCTGGA GCGCTACCTG 
GGAGCCCTCC GTGAGGCCAA GAATGACAGC GAGCAGTTTG CAGCCCTGCT GCTAGTGACC 
AAGGCAGTCA AAGCAGGTGA CATAGATGCC AAAACTCGGC GGCGGATCTT CGATGCTGTC 
GGCTTCACCT TCCCCAATCG TCTCCTGACC ACCAAGGAGG CGCCGGATGG CTGCCCTGAC 
CATGTTCTGC GGGCTTTGGG TGTGGCCCTG CTGGCCTGCT TCTGCAGTGA CCCTGAACTG 
GCCGCCCATC CCCAAGTCCT GAACAAGATT CCCATTCTTA GCACCTTCCT CACAGCCCGG 
GGGGACCCGG ACGATGCTGC CCGCCGCTCC ATGATTGATG ACACCTACCA GTGCCTGACG 
GCTGTAGCAG GCACACCCAG AGGGCCTCGG CACCTCATTG CTGGTGGCAC CGTGTCTGCC 
CTATGCCAGG CATACCTGGG GCACGGCTAT GGCTTTGACC AGGCCCTGGC ACTCCTGGTG 
GGGCTGCTGG CTGCTGCCGA GACACAGTGC TGGAAGGAGG CGGAGCCCGA CCTGCTGGCC 
GTGTTGCGGG GCCTCAGTGA GGATTTCCAG AAAGCTGAGG ATGCCAGCAA GTTTGAGCTC 
TGCCAGCTGC TGCCCCTCTT TTTGCCCCCG ACAACCGTGC CCCCTGAATG CTACCGGGAT 
CTGCAGGCCG GGCTGGCACG CATCCTGGGA AGCAAGCTGA GCTCCTGGCA GCGCAACCCT 
GCACTGAAGC TGGCAGCCCG CCTGGCACAC GCCTGCGGCT CCGACTGGAT CCCGGCGGGC 
AGCTCCGGGA GCAAGTTCCT GGCCCTGCTG GTGAATCTGG CGTGCGTGGA AGTGCGGCTG 
GCACTGGAGG AGACGGGCAC GGAGGTGAAA GAGGATGTGG TGACCGCCTG CTATGCCCTC 
ATGGAGTTGG GGATCCAGGA ATGCACTCGC TGTGAGCAGT CACTGCTTAA GGAGCCACAG 
AAGGTGCAGC TCGTGAGCGT CATGAAGGAG GCCATAGGGG CTGTTATCCA CTACCTGCTG 
CAGGTGGGGT CAGAGAAGCA GAAGGAGCCC TTTGTGTTTG CCTCGGTGCG GATCCTGGGT 
GCCTGGCTGG CCGAGGAGAC CTCATCCTTG CGTAAGGAGG TGTGCCAGCT GCTGCCCTTC 
CTCGTCCGCT ATGCCAAGAC CCTCTACGAG GAGGCCGAGG AGGCCAATGA CCTTTCCCAG 
CAGGTGGCCA ACCTGGCCAT CTCCCCCACC ACCCCAGGGC CCACCTGGCC AGGAGACGCT 
CTCCGGCTCC TCCTGCCTGG CTGGTGCCAC CTGACCGTTG AAGATGGGCC CCGGGAGATC 
CTGATCAAGG AAGGGGCCCC CTCGCTTCTG TGCAAGTATT TCCTGCAGCA GTGGGAACTC 
ACATCCCCTG GCCACGACAC CTCGGTGCTG CCTGACAGCG TGGAGATTGG CCTGCAGACC 
TGCTGCCACA TCTTCCTCAA CCTCGTGGTC ACCGCACCGG GGCTGATCAA GCGTGACGCC 
TGCTTCACAT CTCTAATGAA CACCCTCATG ACGTCGCTAC CAGCACTAGT GCAGCAACAG 
GGAAGGCTGC TTCTGGCTGC TAATGTGGCC ACCCTGGGGC TCCTCATGGC CCGGCTCCTT 
AGCACCTCTC CAGCTCTTCA GGGAACACCA GCATCCCGAG GGTTCTTCGC AGCTGCCATC 
CTCTTCCTAT CACAGTCCCA CGTGGCGCGG GCCACCCCGG GCTCAGACCA GGCAGTGCTA 
GCCCTGTCCC CTGAGTATGA GGGCATCTGG GCCGACCTGC AGGAGCTCTG GTTCCTGGGC 
ATGCAGGCCT TCACCGGCTG TGTGCCTCTG CTGCCCTGGC TGGCCCCCGC TGCCCTGCGC 
TCCCGCTGGC CGCAGGAGCT GCTCCAGCTG CTAGGCAGTG TCAGCCCCAA CTCTGTCAAG 
CCCGAGATGG TGGCCGCCTA TCAGGGTGTC CTGGTGGAGC TGGCGCGGGC CAACCGGCTG 
TGCCGGGAGG CCATGAGGCT GCAGGCGGGC GAGGAGACGG CCAGCCACTA CCGCATGGCT 
GCCTTGGAGC AGTGCCTGTC AGAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCDN ( NM_001014841.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001014841.1 Homo sapiens neurochondrin (NCDN), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu29542
Clone ID Related Accession (Same CDS sequence)	NM_001014841.1
Accession Version	NM_001014841.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2139bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-22
Organism	Homo sapiens(human)
Product	neurochondrin isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL536768.3, AB018740.2, BC024592.1 and AW207151.1. Transcript Variant: This variant (2), also known as NCDN-2, contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus when compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.591773.1, SRR3476690.907316.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCGG ATTGCGAGCC AGCTCTGAAC CAGGCAGAGG GCCGAAACCC CACCCTGGAG 
CGCTACCTGG GAGCCCTCCG TGAGGCCAAG AATGACAGCG AGCAGTTTGC AGCCCTGCTG 
CTAGTGACCA AGGCAGTCAA AGCAGGTGAC ATAGATGCCA AAACTCGGCG GCGGATCTTC 
GATGCTGTCG GCTTCACCTT CCCCAATCGT CTCCTGACCA CCAAGGAGGC GCCGGATGGC 
TGCCCTGACC ATGTTCTGCG GGCTTTGGGT GTGGCCCTGC TGGCCTGCTT CTGCAGTGAC 
CCTGAACTGG CCGCCCATCC CCAAGTCCTG AACAAGATTC CCATTCTTAG CACCTTCCTC 
ACAGCCCGGG GGGACCCGGA CGATGCTGCC CGCCGCTCCA TGATTGATGA CACCTACCAG 
TGCCTGACGG CTGTAGCAGG CACACCCAGA GGGCCTCGGC ACCTCATTGC TGGTGGCACC 
GTGTCTGCCC TATGCCAGGC ATACCTGGGG CACGGCTATG GCTTTGACCA GGCCCTGGCA 
CTCCTGGTGG GGCTGCTGGC TGCTGCCGAG ACACAGTGCT GGAAGGAGGC GGAGCCCGAC 
CTGCTGGCCG TGTTGCGGGG CCTCAGTGAG GATTTCCAGA AAGCTGAGGA TGCCAGCAAG 
TTTGAGCTCT GCCAGCTGCT GCCCCTCTTT TTGCCCCCGA CAACCGTGCC CCCTGAATGC 
TACCGGGATC TGCAGGCCGG GCTGGCACGC ATCCTGGGAA GCAAGCTGAG CTCCTGGCAG 
CGCAACCCTG CACTGAAGCT GGCAGCCCGC CTGGCACACG CCTGCGGCTC CGACTGGATC 
CCGGCGGGCA GCTCCGGGAG CAAGTTCCTG GCCCTGCTGG TGAATCTGGC GTGCGTGGAA 
GTGCGGCTGG CACTGGAGGA GACGGGCACG GAGGTGAAAG AGGATGTGGT GACCGCCTGC 
TATGCCCTCA TGGAGTTGGG GATCCAGGAA TGCACTCGCT GTGAGCAGTC ACTGCTTAAG 
GAGCCACAGA AGGTGCAGCT CGTGAGCGTC ATGAAGGAGG CCATAGGGGC TGTTATCCAC 
TACCTGCTGC AGGTGGGGTC AGAGAAGCAG AAGGAGCCCT TTGTGTTTGC CTCGGTGCGG 
ATCCTGGGTG CCTGGCTGGC CGAGGAGACC TCATCCTTGC GTAAGGAGGT GTGCCAGCTG 
CTGCCCTTCC TCGTCCGCTA TGCCAAGACC CTCTACGAGG AGGCCGAGGA GGCCAATGAC 
CTTTCCCAGC AGGTGGCCAA CCTGGCCATC TCCCCCACCA CCCCAGGGCC CACCTGGCCA 
GGAGACGCTC TCCGGCTCCT CCTGCCTGGC TGGTGCCACC TGACCGTTGA AGATGGGCCC 
CGGGAGATCC TGATCAAGGA AGGGGCCCCC TCGCTTCTGT GCAAGTATTT CCTGCAGCAG 
TGGGAACTCA CATCCCCTGG CCACGACACC TCGGTGCTGC CTGACAGCGT GGAGATTGGC 
CTGCAGACCT GCTGCCACAT CTTCCTCAAC CTCGTGGTCA CCGCACCGGG GCTGATCAAG 
CGTGACGCCT GCTTCACATC TCTAATGAAC ACCCTCATGA CGTCGCTACC AGCACTAGTG 
CAGCAACAGG GAAGGCTGCT TCTGGCTGCT AATGTGGCCA CCCTGGGGCT CCTCATGGCC 
CGGCTCCTTA GCACCTCTCC AGCTCTTCAG GGAACACCAG CATCCCGAGG GTTCTTCGCA 
GCTGCCATCC TCTTCCTATC ACAGTCCCAC GTGGCGCGGG CCACCCCGGG CTCAGACCAG 
GCAGTGCTAG CCCTGTCCCC TGAGTATGAG GGCATCTGGG CCGACCTGCA GGAGCTCTGG 
TTCCTGGGCA TGCAGGCCTT CACCGGCTGT GTGCCTCTGC TGCCCTGGCT GGCCCCCGCT 
GCCCTGCGCT CCCGCTGGCC GCAGGAGCTG CTCCAGCTGC TAGGCAGTGT CAGCCCCAAC 
TCTGTCAAGC CCGAGATGGT GGCCGCCTAT CAGGGTGTCC TGGTGGAGCT GGCGCGGGCC 
AACCGGCTGT GCCGGGAGGC CATGAGGCTG CAGGCGGGCG AGGAGACGGC CAGCCACTAC 
CGCATGGCTG CCTTGGAGCA GTGCCTGTCA GAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014841.1
CDS	111..2249
Translation	MASDCEPALNQAEGRNPTLERYLGALREAKNDSEQFAALLLVTKAVKAGDIDAKTRRRIFDAVGFTFPNRLLTTKEAPDGCPDHVLRALGVALLACFCSDPELAAHPQVLNKIPILSTFLTARGDPDDAARRSMIDDTYQCLTAVAGTPRGPRHLIAGGTVSALCQAYLGHGYGFDQALALLVGLLAAAETQCWKEAEPDLLAVLRGLSEDFQKAEDASKFELCQLLPLFLPPTTVPPECYRDLQAGLARILGSKLSSWQRNPALKLAARLAHACGSDWIPAGSSGSKFLALLVNLACVEVRLALEETGTEVKEDVVTACYALMELGIQECTRCEQSLLKEPQKVQLVSVMKEAIGAVIHYLLQVGSEKQKEPFVFASVRILGAWLAEETSSLRKEVCQLLPFLVRYAKTLYEEAEEANDLSQQVANLAISPTTPGPTWPGDALRLLLPGWCHLTVEDGPREILIKEGAPSLLCKYFLQQWELTSPGHDTSVLPDSVEIGLQTCCHIFLNLVVTAPGLIKRDACFTSLMNTLMTSLPALVQQQGRLLLAANVATLGLLMARLLSTSPALQGTPASRGFFAAAILFLSQSHVARATPGSDQAVLALSPEYEGIWADLQELWFLGMQAFTGCVPLLPWLAPAALRSRWPQELLQLLGSVSPNSVKPEMVAAYQGVLVELARANRLCREAMRLQAGEETASHYRMAALEQCLSEP

Target ORF information:

RefSeq Version	NM_001014841.1
Organism	Homo sapiens(human)
Definition	Homo sapiens neurochondrin (NCDN), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014841.1

ORF Insert Sequence:

ATGGCCTCGG ATTGCGAGCC AGCTCTGAAC CAGGCAGAGG GCCGAAACCC CACCCTGGAG 
CGCTACCTGG GAGCCCTCCG TGAGGCCAAG AATGACAGCG AGCAGTTTGC AGCCCTGCTG 
CTAGTGACCA AGGCAGTCAA AGCAGGTGAC ATAGATGCCA AAACTCGGCG GCGGATCTTC 
GATGCTGTCG GCTTCACCTT CCCCAATCGT CTCCTGACCA CCAAGGAGGC GCCGGATGGC 
TGCCCTGACC ATGTTCTGCG GGCTTTGGGT GTGGCCCTGC TGGCCTGCTT CTGCAGTGAC 
CCTGAACTGG CCGCCCATCC CCAAGTCCTG AACAAGATTC CCATTCTTAG CACCTTCCTC 
ACAGCCCGGG GGGACCCGGA CGATGCTGCC CGCCGCTCCA TGATTGATGA CACCTACCAG 
TGCCTGACGG CTGTAGCAGG CACACCCAGA GGGCCTCGGC ACCTCATTGC TGGTGGCACC 
GTGTCTGCCC TATGCCAGGC ATACCTGGGG CACGGCTATG GCTTTGACCA GGCCCTGGCA 
CTCCTGGTGG GGCTGCTGGC TGCTGCCGAG ACACAGTGCT GGAAGGAGGC GGAGCCCGAC 
CTGCTGGCCG TGTTGCGGGG CCTCAGTGAG GATTTCCAGA AAGCTGAGGA TGCCAGCAAG 
TTTGAGCTCT GCCAGCTGCT GCCCCTCTTT TTGCCCCCGA CAACCGTGCC CCCTGAATGC 
TACCGGGATC TGCAGGCCGG GCTGGCACGC ATCCTGGGAA GCAAGCTGAG CTCCTGGCAG 
CGCAACCCTG CACTGAAGCT GGCAGCCCGC CTGGCACACG CCTGCGGCTC CGACTGGATC 
CCGGCGGGCA GCTCCGGGAG CAAGTTCCTG GCCCTGCTGG TGAATCTGGC GTGCGTGGAA 
GTGCGGCTGG CACTGGAGGA GACGGGCACG GAGGTGAAAG AGGATGTGGT GACCGCCTGC 
TATGCCCTCA TGGAGTTGGG GATCCAGGAA TGCACTCGCT GTGAGCAGTC ACTGCTTAAG 
GAGCCACAGA AGGTGCAGCT CGTGAGCGTC ATGAAGGAGG CCATAGGGGC TGTTATCCAC 
TACCTGCTGC AGGTGGGGTC AGAGAAGCAG AAGGAGCCCT TTGTGTTTGC CTCGGTGCGG 
ATCCTGGGTG CCTGGCTGGC CGAGGAGACC TCATCCTTGC GTAAGGAGGT GTGCCAGCTG 
CTGCCCTTCC TCGTCCGCTA TGCCAAGACC CTCTACGAGG AGGCCGAGGA GGCCAATGAC 
CTTTCCCAGC AGGTGGCCAA CCTGGCCATC TCCCCCACCA CCCCAGGGCC CACCTGGCCA 
GGAGACGCTC TCCGGCTCCT CCTGCCTGGC TGGTGCCACC TGACCGTTGA AGATGGGCCC 
CGGGAGATCC TGATCAAGGA AGGGGCCCCC TCGCTTCTGT GCAAGTATTT CCTGCAGCAG 
TGGGAACTCA CATCCCCTGG CCACGACACC TCGGTGCTGC CTGACAGCGT GGAGATTGGC 
CTGCAGACCT GCTGCCACAT CTTCCTCAAC CTCGTGGTCA CCGCACCGGG GCTGATCAAG 
CGTGACGCCT GCTTCACATC TCTAATGAAC ACCCTCATGA CGTCGCTACC AGCACTAGTG 
CAGCAACAGG GAAGGCTGCT TCTGGCTGCT AATGTGGCCA CCCTGGGGCT CCTCATGGCC 
CGGCTCCTTA GCACCTCTCC AGCTCTTCAG GGAACACCAG CATCCCGAGG GTTCTTCGCA 
GCTGCCATCC TCTTCCTATC ACAGTCCCAC GTGGCGCGGG CCACCCCGGG CTCAGACCAG 
GCAGTGCTAG CCCTGTCCCC TGAGTATGAG GGCATCTGGG CCGACCTGCA GGAGCTCTGG 
TTCCTGGGCA TGCAGGCCTT CACCGGCTGT GTGCCTCTGC TGCCCTGGCT GGCCCCCGCT 
GCCCTGCGCT CCCGCTGGCC GCAGGAGCTG CTCCAGCTGC TAGGCAGTGT CAGCCCCAAC 
TCTGTCAAGC CCGAGATGGT GGCCGCCTAT CAGGGTGTCC TGGTGGAGCT GGCGCGGGCC 
AACCGGCTGT GCCGGGAGGC CATGAGGCTG CAGGCGGGCG AGGAGACGGC CAGCCACTAC 
CGCATGGCTG CCTTGGAGCA GTGCCTGTCA GAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Altered Norbin Expression in Patients with Epilepsy and a Rat Model.
Scientific reports7(1)13970(2017 Oct)
Xu Y,Li Z,Yao L,Zhang X,Gan D,Jiang M,Wang N,Chen G,Wang X

Neurochondrin is an atypical RII?-specific A-kinase anchoring protein.
Biochimica et biophysica acta1854(10 Pt B)1667-75(2015 Oct)
Hermann JS,Skroblin P,Bertinetti D,Hanold LE,von der Heide EK,Wagener EM,Zenn HM,Klussmann E,Kennedy EJ,Herberg FW

Metabotropic glutamate receptor 5, and its trafficking molecules Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia.
Schizophrenia research166(1-3)212-8(2015 Aug)
Matosin N,Fernandez-Enright F,Lum JS,Andrews JL,Engel M,Huang XF,Newell KA

In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes.
The Journal of biological chemistry288(27)19816-29(2013 Jul)
Oku S,Takahashi N,Fukata Y,Fukata M

Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
Journal of proteome research11(4)2533-43(2012 Apr)
Martins-de-Souza D,Guest PC,Mann DM,Roeber S,Rahmoune H,Bauder C,Kretzschmar H,Volk B,Baborie A,Bahn S

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

NCDN cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報