FOXC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FOXC2
Entrez Gene ID	2303
Full Name	forkhead box C2
Synonyms	FKHL14,LD,MFH-1,MFH1
General protein information	Preferred Names forkhead box C2 Names forkhead box protein C2 MFH-1,mesenchyme forkhead 1 forkhead box C2 (MFH-1, mesenchyme forkhead 1) forkhead, Drosophila, homolog-like 14 forkhead-related protein FKHL14 mesenchyme fork head protein 1 mesenchyme forkhead 1 transcription factor FKH-14
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q24.1
Summary	This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues. [provided by RefSeq, Jul 2008].
Disorder MIM:	602402
Disorder Html:	Lymphedema-distichiasis syndrome, 153400 (3); Lymphedema-distichiasis syndrome with renal disease and diabetes mellitus, 153400 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_005251.2	NP_005242.1	forkhead box protein C2
NM_005251.3	NP_005242.1	forkhead box protein C2

Pathways from BioSystems

Homologies

	FOXC2	XP_001085933.1
Xenopus tropicalis (tropical clawed frog)	foxc2	NP_998857.1
Canis lupus familiaris (dog)	FOXC2	XP_005620648.1
Homo sapiens (human)	FOXC2	NP_005242.1
Pan troglodytes (chimpanzee)	FOXC2	XP_523450.3
Rattus norvegicus (Norway rat)	Foxc2	NP_001095150.1
Bos taurus (cattle)	FOXC2	NP_001180001.1
Mus musculus (house mouse)	Foxc2	NP_038547.2
Gallus gallus (chicken)	FOXC2	NP_990469.1

Gene Ontology

The following FOXC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FOXC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19307	NM_005251.3 Latest version!	Homo sapiens forkhead box C2 (FOXC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
View Old Accession Versions >>
OHu19307	NM_005251.2	Homo sapiens forkhead box C2 (FOXC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FOXC2 ( NM_005251.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_005242.1 Homo sapiens forkhead box C2 (FOXC2), mRNA.

Price & Availability↑

CloneID	OHu19307
Clone ID Related Accession (Same CDS sequence)	NM_005251.2 , NM_005251.3
Accession Version	NM_005251.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1506bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	forkhead box protein C2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC113439.1. This sequence is a reference standard in the RefSeqGene project. On Aug 29, 2008 this sequence version replaced NM_005251.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC113439.1, BC113437.1 [ECO:0000345] ##Evidence-Data-END##

ATGCAGGCGC GCTACTCCGT GTCCGACCCC AACGCCCTGG GAGTGGTGCC CTACCTGAGC 
GAGCAGAATT ACTACCGGGC TGCGGGCAGC TACGGCGGCA TGGCCAGCCC CATGGGCGTC 
TATTCCGGCC ACCCGGAGCA GTACAGCGCG GGGATGGGCC GCTCCTACGC GCCCTACCAC 
CACCACCAGC CCGCGGCGCC TAAGGACCTG GTGAAGCCGC CCTACAGCTA CATCGCGCTC 
ATCACCATGG CCATCCAGAA CGCGCCCGAG AAGAAGATCA CCTTGAACGG CATCTACCAG 
TTCATCATGG ACCGCTTCCC CTTCTACCGG GAGAACAAGC AGGGCTGGCA GAACAGCATC 
CGCCACAACC TCTCGCTCAA CGAGTGCTTC GTCAAGGTGC CCCGCGACGA CAAGAAGCCC 
GGCAAGGGCA GTTACTGGAC CCTGGACCCG GACTCCTACA ACATGTTCGA GAACGGCAGC 
TTCCTGCGGC GCCGGCGGCG CTTCAAAAAG AAGGACGTGT CCAAGGAGAA GGAGGAGCGG 
GCCCACCTCA AGGAGCCGCC CCCGGCGGCG TCCAAGGGCG CCCCGGCCAC CCCCCACCTA 
GCGGACGCCC CCAAGGAGGC CGAGAAGAAG GTGGTGATCA AGAGCGAGGC GGCGTCCCCG 
GCGCTGCCGG TCATCACCAA GGTGGAGACG CTGAGCCCCG AGAGCGCGCT GCAGGGCAGC 
CCGCGCAGCG CGGCCTCCAC GCCCGCCGGC TCCCCCGACG GCTCGCTGCC GGAGCACCAC 
GCCGCGGCGC CCAACGGGCT GCCTGGCTTC AGCGTGGAGA ACATCATGAC CCTGCGAACG 
TCGCCGCCGG GCGGAGAGCT GAGCCCGGGG GCCGGACGCG CGGGCCTGGT GGTGCCGCCG 
CTGGCGCTGC CCTACGCCGC CGCGCCGCCC GCCGCCTACG GCCAGCCGTG CGCTCAGGGC 
CTGGAGGCCG GGGCCGCCGG GGGCTACCAG TGCAGCATGC GAGCGATGAG CCTGTACACC 
GGGGCCGAGC GGCCGGCGCA CATGTGCGTC CCGCCCGCCC TGGACGAGGC CCTCTCGGAC 
CACCCGAGCG GCCCCACGTC GCCCCTGAGC GCTCTCAACC TCGCCGCCGG CCAGGAGGGC 
GCGCTCGCCG CCACGGGCCA CCACCACCAG CACCACGGCC ACCACCACCC GCAGGCGCCG 
CCGCCCCCGC CGGCTCCCCA GCCCCAGCCG ACGCCGCAGC CCGGGGCCGC CGCGGCGCAG 
GCGGCCTCCT GGTATCTCAA CCACAGCGGG GACCTGAACC ACCTCCCCGG CCACACGTTC 
GCGGCCCAGC AGCAAACTTT CCCCAACGTG CGGGAGATGT TCAACTCCCA CCGGCTGGGG 
ATTGAGAACT CGACCCTCGG GGAGTCCCAG GTGAGTGGCA ATGCCAGCTG CCAGCTGCCC 
TACAGATCCA CGCCGCCTCT CTATCGCCAC GCAGCCCCCT ACTCCTACGA CTGCACGAAA 
TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005242.1
CDS	86..1591
Translation	MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKEKEERAHLKEPPPAASKGAPATPHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPESALQGSPRSAASTPAGSPDGSLPEHHAAAPNGLPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQPCAQGLEAGAAGGYQCSMRAMSLYTGAERPAHMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHHHPQAPPPPPAPQPQPTPQPGAAAAQAASWYLNHSGDLNHLPGHTFAAQQQTFPNVREMFNSHRLGIENSTLGESQVSGNASCQLPYRSTPPLYRHAAPYSYDCTKY

Target ORF information:

RefSeq Version	NM_005251.2
Organism	Homo sapiens(human)
Definition	Homo sapiens forkhead box C2 (FOXC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005251.2

ORF Insert Sequence:

ATGCAGGCGC GCTACTCCGT GTCCGACCCC AACGCCCTGG GAGTGGTGCC CTACCTGAGC 
GAGCAGAATT ACTACCGGGC TGCGGGCAGC TACGGCGGCA TGGCCAGCCC CATGGGCGTC 
TATTCCGGCC ACCCGGAGCA GTACAGCGCG GGGATGGGCC GCTCCTACGC GCCCTACCAC 
CACCACCAGC CCGCGGCGCC TAAGGACCTG GTGAAGCCGC CCTACAGCTA CATCGCGCTC 
ATCACCATGG CCATCCAGAA CGCGCCCGAG AAGAAGATCA CCTTGAACGG CATCTACCAG 
TTCATCATGG ACCGCTTCCC CTTCTACCGG GAGAACAAGC AGGGCTGGCA GAACAGCATC 
CGCCACAACC TCTCGCTCAA CGAGTGCTTC GTCAAGGTGC CCCGCGACGA CAAGAAGCCC 
GGCAAGGGCA GTTACTGGAC CCTGGACCCG GACTCCTACA ACATGTTCGA GAACGGCAGC 
TTCCTGCGGC GCCGGCGGCG CTTCAAAAAG AAGGACGTGT CCAAGGAGAA GGAGGAGCGG 
GCCCACCTCA AGGAGCCGCC CCCGGCGGCG TCCAAGGGCG CCCCGGCCAC CCCCCACCTA 
GCGGACGCCC CCAAGGAGGC CGAGAAGAAG GTGGTGATCA AGAGCGAGGC GGCGTCCCCG 
GCGCTGCCGG TCATCACCAA GGTGGAGACG CTGAGCCCCG AGAGCGCGCT GCAGGGCAGC 
CCGCGCAGCG CGGCCTCCAC GCCCGCCGGC TCCCCCGACG GCTCGCTGCC GGAGCACCAC 
GCCGCGGCGC CCAACGGGCT GCCTGGCTTC AGCGTGGAGA ACATCATGAC CCTGCGAACG 
TCGCCGCCGG GCGGAGAGCT GAGCCCGGGG GCCGGACGCG CGGGCCTGGT GGTGCCGCCG 
CTGGCGCTGC CCTACGCCGC CGCGCCGCCC GCCGCCTACG GCCAGCCGTG CGCTCAGGGC 
CTGGAGGCCG GGGCCGCCGG GGGCTACCAG TGCAGCATGC GAGCGATGAG CCTGTACACC 
GGGGCCGAGC GGCCGGCGCA CATGTGCGTC CCGCCCGCCC TGGACGAGGC CCTCTCGGAC 
CACCCGAGCG GCCCCACGTC GCCCCTGAGC GCTCTCAACC TCGCCGCCGG CCAGGAGGGC 
GCGCTCGCCG CCACGGGCCA CCACCACCAG CACCACGGCC ACCACCACCC GCAGGCGCCG 
CCGCCCCCGC CGGCTCCCCA GCCCCAGCCG ACGCCGCAGC CCGGGGCCGC CGCGGCGCAG 
GCGGCCTCCT GGTATCTCAA CCACAGCGGG GACCTGAACC ACCTCCCCGG CCACACGTTC 
GCGGCCCAGC AGCAAACTTT CCCCAACGTG CGGGAGATGT TCAACTCCCA CCGGCTGGGG 
ATTGAGAACT CGACCCTCGG GGAGTCCCAG GTGAGTGGCA ATGCCAGCTG CCAGCTGCCC 
TACAGATCCA CGCCGCCTCT CTATCGCCAC GCAGCCCCCT ACTCCTACGA CTGCACGAAA 
TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FOXC2 ( NM_005251.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005242.1 Homo sapiens forkhead box C2 (FOXC2), mRNA.

Price & Availability↑

CloneID	OHu19307
Clone ID Related Accession (Same CDS sequence)	NM_005251.2 , NM_005251.3
Accession Version	NM_005251.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1506bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	forkhead box protein C2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC009108.10 and BC113439.1. This sequence is a reference standard in the RefSeqGene project. On Oct 16, 2018 this sequence version replaced NM_005251.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC113439.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000649859.1/ ENSP00000497759.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCAGGCGC GCTACTCCGT GTCCGACCCC AACGCCCTGG GAGTGGTGCC CTACCTGAGC 
GAGCAGAATT ACTACCGGGC TGCGGGCAGC TACGGCGGCA TGGCCAGCCC CATGGGCGTC 
TATTCCGGCC ACCCGGAGCA GTACAGCGCG GGGATGGGCC GCTCCTACGC GCCCTACCAC 
CACCACCAGC CCGCGGCGCC TAAGGACCTG GTGAAGCCGC CCTACAGCTA CATCGCGCTC 
ATCACCATGG CCATCCAGAA CGCGCCCGAG AAGAAGATCA CCTTGAACGG CATCTACCAG 
TTCATCATGG ACCGCTTCCC CTTCTACCGG GAGAACAAGC AGGGCTGGCA GAACAGCATC 
CGCCACAACC TCTCGCTCAA CGAGTGCTTC GTCAAGGTGC CCCGCGACGA CAAGAAGCCC 
GGCAAGGGCA GTTACTGGAC CCTGGACCCG GACTCCTACA ACATGTTCGA GAACGGCAGC 
TTCCTGCGGC GCCGGCGGCG CTTCAAAAAG AAGGACGTGT CCAAGGAGAA GGAGGAGCGG 
GCCCACCTCA AGGAGCCGCC CCCGGCGGCG TCCAAGGGCG CCCCGGCCAC CCCCCACCTA 
GCGGACGCCC CCAAGGAGGC CGAGAAGAAG GTGGTGATCA AGAGCGAGGC GGCGTCCCCG 
GCGCTGCCGG TCATCACCAA GGTGGAGACG CTGAGCCCCG AGAGCGCGCT GCAGGGCAGC 
CCGCGCAGCG CGGCCTCCAC GCCCGCCGGC TCCCCCGACG GCTCGCTGCC GGAGCACCAC 
GCCGCGGCGC CCAACGGGCT GCCTGGCTTC AGCGTGGAGA ACATCATGAC CCTGCGAACG 
TCGCCGCCGG GCGGAGAGCT GAGCCCGGGG GCCGGACGCG CGGGCCTGGT GGTGCCGCCG 
CTGGCGCTGC CCTACGCCGC CGCGCCGCCC GCCGCCTACG GCCAGCCGTG CGCTCAGGGC 
CTGGAGGCCG GGGCCGCCGG GGGCTACCAG TGCAGCATGC GAGCGATGAG CCTGTACACC 
GGGGCCGAGC GGCCGGCGCA CATGTGCGTC CCGCCCGCCC TGGACGAGGC CCTCTCGGAC 
CACCCGAGCG GCCCCACGTC GCCCCTGAGC GCTCTCAACC TCGCCGCCGG CCAGGAGGGC 
GCGCTCGCCG CCACGGGCCA CCACCACCAG CACCACGGCC ACCACCACCC GCAGGCGCCG 
CCGCCCCCGC CGGCTCCCCA GCCCCAGCCG ACGCCGCAGC CCGGGGCCGC CGCGGCGCAG 
GCGGCCTCCT GGTATCTCAA CCACAGCGGG GACCTGAACC ACCTCCCCGG CCACACGTTC 
GCGGCCCAGC AGCAAACTTT CCCCAACGTG CGGGAGATGT TCAACTCCCA CCGGCTGGGG 
ATTGAGAACT CGACCCTCGG GGAGTCCCAG GTGAGTGGCA ATGCCAGCTG CCAGCTGCCC 
TACAGATCCA CGCCGCCTCT CTATCGCCAC GCAGCCCCCT ACTCCTACGA CTGCACGAAA 
TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005242.1
CDS	508..2013
Translation	MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVSKEKEERAHLKEPPPAASKGAPATPHLADAPKEAEKKVVIKSEAASPALPVITKVETLSPESALQGSPRSAASTPAGSPDGSLPEHHAAAPNGLPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQPCAQGLEAGAAGGYQCSMRAMSLYTGAERPAHMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHHHPQAPPPPPAPQPQPTPQPGAAAAQAASWYLNHSGDLNHLPGHTFAAQQQTFPNVREMFNSHRLGIENSTLGESQVSGNASCQLPYRSTPPLYRHAAPYSYDCTKY

Target ORF information:

RefSeq Version	NM_005251.3
Organism	Homo sapiens(human)
Definition	Homo sapiens forkhead box C2 (FOXC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005251.3

ORF Insert Sequence:

ATGCAGGCGC GCTACTCCGT GTCCGACCCC AACGCCCTGG GAGTGGTGCC CTACCTGAGC 
GAGCAGAATT ACTACCGGGC TGCGGGCAGC TACGGCGGCA TGGCCAGCCC CATGGGCGTC 
TATTCCGGCC ACCCGGAGCA GTACAGCGCG GGGATGGGCC GCTCCTACGC GCCCTACCAC 
CACCACCAGC CCGCGGCGCC TAAGGACCTG GTGAAGCCGC CCTACAGCTA CATCGCGCTC 
ATCACCATGG CCATCCAGAA CGCGCCCGAG AAGAAGATCA CCTTGAACGG CATCTACCAG 
TTCATCATGG ACCGCTTCCC CTTCTACCGG GAGAACAAGC AGGGCTGGCA GAACAGCATC 
CGCCACAACC TCTCGCTCAA CGAGTGCTTC GTCAAGGTGC CCCGCGACGA CAAGAAGCCC 
GGCAAGGGCA GTTACTGGAC CCTGGACCCG GACTCCTACA ACATGTTCGA GAACGGCAGC 
TTCCTGCGGC GCCGGCGGCG CTTCAAAAAG AAGGACGTGT CCAAGGAGAA GGAGGAGCGG 
GCCCACCTCA AGGAGCCGCC CCCGGCGGCG TCCAAGGGCG CCCCGGCCAC CCCCCACCTA 
GCGGACGCCC CCAAGGAGGC CGAGAAGAAG GTGGTGATCA AGAGCGAGGC GGCGTCCCCG 
GCGCTGCCGG TCATCACCAA GGTGGAGACG CTGAGCCCCG AGAGCGCGCT GCAGGGCAGC 
CCGCGCAGCG CGGCCTCCAC GCCCGCCGGC TCCCCCGACG GCTCGCTGCC GGAGCACCAC 
GCCGCGGCGC CCAACGGGCT GCCTGGCTTC AGCGTGGAGA ACATCATGAC CCTGCGAACG 
TCGCCGCCGG GCGGAGAGCT GAGCCCGGGG GCCGGACGCG CGGGCCTGGT GGTGCCGCCG 
CTGGCGCTGC CCTACGCCGC CGCGCCGCCC GCCGCCTACG GCCAGCCGTG CGCTCAGGGC 
CTGGAGGCCG GGGCCGCCGG GGGCTACCAG TGCAGCATGC GAGCGATGAG CCTGTACACC 
GGGGCCGAGC GGCCGGCGCA CATGTGCGTC CCGCCCGCCC TGGACGAGGC CCTCTCGGAC 
CACCCGAGCG GCCCCACGTC GCCCCTGAGC GCTCTCAACC TCGCCGCCGG CCAGGAGGGC 
GCGCTCGCCG CCACGGGCCA CCACCACCAG CACCACGGCC ACCACCACCC GCAGGCGCCG 
CCGCCCCCGC CGGCTCCCCA GCCCCAGCCG ACGCCGCAGC CCGGGGCCGC CGCGGCGCAG 
GCGGCCTCCT GGTATCTCAA CCACAGCGGG GACCTGAACC ACCTCCCCGG CCACACGTTC 
GCGGCCCAGC AGCAAACTTT CCCCAACGTG CGGGAGATGT TCAACTCCCA CCGGCTGGGG 
ATTGAGAACT CGACCCTCGG GGAGTCCCAG GTGAGTGGCA ATGCCAGCTG CCAGCTGCCC 
TACAGATCCA CGCCGCCTCT CTATCGCCAC GCAGCCCCCT ACTCCTACGA CTGCACGAAA 
TACTGA