RAET1L cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RAET1L
Entrez Gene ID	154064
Full Name	retinoic acid early transcript 1L
Synonyms	ULBP6
General protein information	Preferred Names retinoic acid early transcript 1L Names UL16-binding protein 6 retinoic acid early transcript 1L protein UL16 binding protein 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q25.1
Summary	RAET1L belongs to the RAET1 family of major histocompatibility complex (MHC) class I-related genes, which are located within a 180-kb cluster on chromosome 6q24.2-q25.3. The REAT1 genes encode glycoproteins that contain extracellular alpha-1 and alpha-2 domains, but they lack the membrane proximal Ig-like alpha-3 domain. Most RAET1 glycoproteins are anchored to the membrane via glycosylphosphatidylinositol (GPI) linkage (Radosavljevic et al., 2002 [PubMed 11827464]).[supplied by OMIM, Mar 2008].
Disorder MIM:	611047

mRNA and Protein(s)

mRNA	Protein	Name
NM_130900.3	NP_570970.2	UL16-binding protein 6 precursor
XM_011535486.2	XP_011533788.1	UL16-binding protein 6 isoform X1
NM_130900.2	NP_570970.2	UL16-binding protein 6 precursor

Pathways from BioSystems

Homologies

	LOC694265	XP_001082968.2
Homo sapiens (human)	RAET1L	NP_570970.2
Pan troglodytes (chimpanzee)	RAET1L	XP_518876.2
	LOC694076	XP_001082014.2

Gene Ontology
Bibliography

Related articles in PubMed

A disease-linked
Zuo J, Willcox CR, Mohammed F, Davey M, Hunter S, Khan K, Antoun A, Katakia P, Croudace J, Inman C, Parry H, Briggs D, Malladi R, Willcox BE, Moss P
Science signaling10(481)(2017 May)

Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.
Wennerberg E, Pfefferle A, Ekblad L, Yoshimoto Y, Kremer V, Kaminskyy VO, Juhlin CC, H??g A, Bodin I, Svjatoha V, Larsson C, Zedenius J, Wennerberg J, Lundqvist A
Clinical cancer research : an official journal of the American Association for Cancer Research20(22)5733-44(2014 Nov)

The genotype of RAET1L (ULBP6), a ligand for human NKG2D (KLRK1), markedly influences the clinical outcome of allogeneic stem cell transplantation.
Antoun A, Vekaria D, Salama RA, Pratt G, Jobson S, Cook M, Briggs D, Moss P
British journal of haematology159(5)589-98(2012 Dec)

Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.
Antoun A, Jobson S, Cook M, O'Callaghan CA, Moss P, Briggs DC
Human immunology71(6)610-20(2010 Jun)

New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.
Title: Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.

RAET1L may have an important influence on regulating the strength of the alloreactive immune response in hematologic maliganacies treated with allogeneic stem cell transplantation.
Title: The genotype of RAET1L (ULBP6), a ligand for human NKG2D (KLRK1), markedly influences the clinical outcome of allogeneic stem cell transplantation.

Observational study of genotype prevalence. (HuGE Navigator)
Title: Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.

Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.

Observational study of genotype prevalence. (HuGE Navigator)
Title: Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in northeastern Thais.

The following RAET1L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAET1L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05928	NM_130900.3 Latest version!	Homo sapiens retinoic acid early transcript 1L (RAET1L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu05928	XM_011535486.2 Latest version!	Homo sapiens retinoic acid early transcript 1L (RAET1L), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu05928	NM_130900.2	Homo sapiens retinoic acid early transcript 1L (RAET1L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RAET1L ( NM_130900.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_570970.2 Homo sapiens retinoic acid early transcript 1L (RAET1L), mRNA.

Price & Availability↑

CloneID	OHu05928
Clone ID Related Accession (Same CDS sequence)	NM_130900.3 , XM_011535486.2 , NM_130900.2
Accession Version	NM_130900.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	UL16-binding protein 6 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA442768.1, AY039682.1 and AL355497.14. On or before Apr 15, 2019 this sequence version replaced XM_011535486.2, NM_130900.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: DRR138509.52765.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367341.6/ ENSP00000356310.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGCAGCAG CCGCCATCCC AGCTTTGCTT CTGTGCCTCC CGCTTCTGTT CCTGCTGTTC 
GGCTGGTCCC GGGCTAGGCG AGACGACCCT CACTCTCTTT GCTATGACAT CACCGTCATC 
CCTAAGTTCA GACCTGGACC ACGGTGGTGT GCGGTTCAAG GCCAGGTGGA TGAAAAGACT 
TTTCTTCACT ATGACTGTGG CAACAAGACA GTCACACCCG TCAGTCCCCT GGGGAAGAAA 
CTAAATGTCA CAATGGCCTG GAAAGCACAG AACCCAGTAC TGAGAGAGGT GGTGGACATA 
CTTACAGAGC AACTGCTTGA CATTCAGCTG GAGAATTACA CACCCAAGGA ACCCCTCACC 
CTGCAGGCAA GGATGTCTTG TGAGCAGAAA GCTGAAGGAC ACAGCAGTGG ATCTTGGCAG 
TTCAGTATCG ATGGACAGAC CTTCCTACTC TTTGACTCAG AGAAGAGAAT GTGGACAACG 
GTTCATCCTG GAGCCAGAAA GATGAAAGAA AAGTGGGAGA ATGACAAGGA TGTGGCCATG 
TCCTTCCATT ACATCTCAAT GGGAGACTGC ATAGGATGGC TTGAGGACTT CTTGATGGGC 
ATGGACAGCA CCCTGGAGCC AAGTGCAGGA GCACCACTCG CCATGTCCTC AGGCACAACC 
CAACTCAGGG CCACAGCCAC CACCCTCATC CTTTGCTGCC TCCTCATCAT CCTCCCCTGC 
TTCATCCTCC CTGGCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_570970.2
CDS	62..802
Translation	MAAAAIPALLLCLPLLFLLFGWSRARRDDPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGNKTVTPVSPLGKKLNVTMAWKAQNPVLREVVDILTEQLLDIQLENYTPKEPLTLQARMSCEQKAEGHSSGSWQFSIDGQTFLLFDSEKRMWTTVHPGARKMKEKWENDKDVAMSFHYISMGDCIGWLEDFLMGMDSTLEPSAGAPLAMSSGTTQLRATATTLILCCLLIILPCFILPGI

Target ORF information:

RefSeq Version	NM_130900.3
Organism	Homo sapiens(human)
Definition	Homo sapiens retinoic acid early transcript 1L (RAET1L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130900.3

ORF Insert Sequence:

ATGGCAGCAG CCGCCATCCC AGCTTTGCTT CTGTGCCTCC CGCTTCTGTT CCTGCTGTTC 
GGCTGGTCCC GGGCTAGGCG AGACGACCCT CACTCTCTTT GCTATGACAT CACCGTCATC 
CCTAAGTTCA GACCTGGACC ACGGTGGTGT GCGGTTCAAG GCCAGGTGGA TGAAAAGACT 
TTTCTTCACT ATGACTGTGG CAACAAGACA GTCACACCCG TCAGTCCCCT GGGGAAGAAA 
CTAAATGTCA CAATGGCCTG GAAAGCACAG AACCCAGTAC TGAGAGAGGT GGTGGACATA 
CTTACAGAGC AACTGCTTGA CATTCAGCTG GAGAATTACA CACCCAAGGA ACCCCTCACC 
CTGCAGGCAA GGATGTCTTG TGAGCAGAAA GCTGAAGGAC ACAGCAGTGG ATCTTGGCAG 
TTCAGTATCG ATGGACAGAC CTTCCTACTC TTTGACTCAG AGAAGAGAAT GTGGACAACG 
GTTCATCCTG GAGCCAGAAA GATGAAAGAA AAGTGGGAGA ATGACAAGGA TGTGGCCATG 
TCCTTCCATT ACATCTCAAT GGGAGACTGC ATAGGATGGC TTGAGGACTT CTTGATGGGC 
ATGGACAGCA CCCTGGAGCC AAGTGCAGGA GCACCACTCG CCATGTCCTC AGGCACAACC 
CAACTCAGGG CCACAGCCAC CACCCTCATC CTTTGCTGCC TCCTCATCAT CCTCCCCTGC 
TTCATCCTCC CTGGCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAET1L ( NM_130900.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_570970.2 Homo sapiens retinoic acid early transcript 1L (RAET1L), mRNA.

Price & Availability↑

CloneID	OHu05928
Clone ID Related Accession (Same CDS sequence)	NM_130900.3 , XM_011535486.2 , NM_130900.2
Accession Version	NM_130900.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	UL16-binding protein 6 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA442768.1, AL355497.14 and AY039682.1. On Mar 8, 2007 this sequence version replaced NM_130900.1. ##Evidence-Data-START## Transcript exon combination :: AY039682.1, BC131600.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGCAG CCGCCATCCC AGCTTTGCTT CTGTGCCTCC CGCTTCTGTT CCTGCTGTTC 
GGCTGGTCCC GGGCTAGGCG AGACGACCCT CACTCTCTTT GCTATGACAT CACCGTCATC 
CCTAAGTTCA GACCTGGACC ACGGTGGTGT GCGGTTCAAG GCCAGGTGGA TGAAAAGACT 
TTTCTTCACT ATGACTGTGG CAACAAGACA GTCACACCCG TCAGTCCCCT GGGGAAGAAA 
CTAAATGTCA CAATGGCCTG GAAAGCACAG AACCCAGTAC TGAGAGAGGT GGTGGACATA 
CTTACAGAGC AACTGCTTGA CATTCAGCTG GAGAATTACA CACCCAAGGA ACCCCTCACC 
CTGCAGGCAA GGATGTCTTG TGAGCAGAAA GCTGAAGGAC ACAGCAGTGG ATCTTGGCAG 
TTCAGTATCG ATGGACAGAC CTTCCTACTC TTTGACTCAG AGAAGAGAAT GTGGACAACG 
GTTCATCCTG GAGCCAGAAA GATGAAAGAA AAGTGGGAGA ATGACAAGGA TGTGGCCATG 
TCCTTCCATT ACATCTCAAT GGGAGACTGC ATAGGATGGC TTGAGGACTT CTTGATGGGC 
ATGGACAGCA CCCTGGAGCC AAGTGCAGGA GCACCACTCG CCATGTCCTC AGGCACAACC 
CAACTCAGGG CCACAGCCAC CACCCTCATC CTTTGCTGCC TCCTCATCAT CCTCCCCTGC 
TTCATCCTCC CTGGCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_570970.2
CDS	62..802
Translation	MAAAAIPALLLCLPLLFLLFGWSRARRDDPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGNKTVTPVSPLGKKLNVTMAWKAQNPVLREVVDILTEQLLDIQLENYTPKEPLTLQARMSCEQKAEGHSSGSWQFSIDGQTFLLFDSEKRMWTTVHPGARKMKEKWENDKDVAMSFHYISMGDCIGWLEDFLMGMDSTLEPSAGAPLAMSSGTTQLRATATTLILCCLLIILPCFILPGI

Target ORF information:

RefSeq Version	NM_130900.2
Organism	Homo sapiens(human)
Definition	Homo sapiens retinoic acid early transcript 1L (RAET1L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130900.2

ORF Insert Sequence:

ATGGCAGCAG CCGCCATCCC AGCTTTGCTT CTGTGCCTCC CGCTTCTGTT CCTGCTGTTC 
GGCTGGTCCC GGGCTAGGCG AGACGACCCT CACTCTCTTT GCTATGACAT CACCGTCATC 
CCTAAGTTCA GACCTGGACC ACGGTGGTGT GCGGTTCAAG GCCAGGTGGA TGAAAAGACT 
TTTCTTCACT ATGACTGTGG CAACAAGACA GTCACACCCG TCAGTCCCCT GGGGAAGAAA 
CTAAATGTCA CAATGGCCTG GAAAGCACAG AACCCAGTAC TGAGAGAGGT GGTGGACATA 
CTTACAGAGC AACTGCTTGA CATTCAGCTG GAGAATTACA CACCCAAGGA ACCCCTCACC 
CTGCAGGCAA GGATGTCTTG TGAGCAGAAA GCTGAAGGAC ACAGCAGTGG ATCTTGGCAG 
TTCAGTATCG ATGGACAGAC CTTCCTACTC TTTGACTCAG AGAAGAGAAT GTGGACAACG 
GTTCATCCTG GAGCCAGAAA GATGAAAGAA AAGTGGGAGA ATGACAAGGA TGTGGCCATG 
TCCTTCCATT ACATCTCAAT GGGAGACTGC ATAGGATGGC TTGAGGACTT CTTGATGGGC 
ATGGACAGCA CCCTGGAGCC AAGTGCAGGA GCACCACTCG CCATGTCCTC AGGCACAACC 
CAACTCAGGG CCACAGCCAC CACCCTCATC CTTTGCTGCC TCCTCATCAT CCTCCCCTGC 
TTCATCCTCC CTGGCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RAET1L ( XM_011535486.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011533788.1 Homo sapiens retinoic acid early transcript 1L (RAET1L), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu05928
Clone ID Related Accession (Same CDS sequence)	NM_130900.3 , XM_011535486.2 , NM_130900.2
Accession Version	XM_011535486.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	UL16-binding protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535486.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCAGCAG CCGCCATCCC AGCTTTGCTT CTGTGCCTCC CGCTTCTGTT CCTGCTGTTC 
GGCTGGTCCC GGGCTAGGCG AGACGACCCT CACTCTCTTT GCTATGACAT CACCGTCATC 
CCTAAGTTCA GACCTGGACC ACGGTGGTGT GCGGTTCAAG GCCAGGTGGA TGAAAAGACT 
TTTCTTCACT ATGACTGTGG CAACAAGACA GTCACACCCG TCAGTCCCCT GGGGAAGAAA 
CTAAATGTCA CAATGGCCTG GAAAGCACAG AACCCAGTAC TGAGAGAGGT GGTGGACATA 
CTTACAGAGC AACTGCTTGA CATTCAGCTG GAGAATTACA CACCCAAGGA ACCCCTCACC 
CTGCAGGCAA GGATGTCTTG TGAGCAGAAA GCTGAAGGAC ACAGCAGTGG ATCTTGGCAG 
TTCAGTATCG ATGGACAGAC CTTCCTACTC TTTGACTCAG AGAAGAGAAT GTGGACAACG 
GTTCATCCTG GAGCCAGAAA GATGAAAGAA AAGTGGGAGA ATGACAAGGA TGTGGCCATG 
TCCTTCCATT ACATCTCAAT GGGAGACTGC ATAGGATGGC TTGAGGACTT CTTGATGGGC 
ATGGACAGCA CCCTGGAGCC AAGTGCAGGA GCACCACTCG CCATGTCCTC AGGCACAACC 
CAACTCAGGG CCACAGCCAC CACCCTCATC CTTTGCTGCC TCCTCATCAT CCTCCCCTGC 
TTCATCCTCC CTGGCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011533788.1
CDS	126..866
Translation	MAAAAIPALLLCLPLLFLLFGWSRARRDDPHSLCYDITVIPKFRPGPRWCAVQGQVDEKTFLHYDCGNKTVTPVSPLGKKLNVTMAWKAQNPVLREVVDILTEQLLDIQLENYTPKEPLTLQARMSCEQKAEGHSSGSWQFSIDGQTFLLFDSEKRMWTTVHPGARKMKEKWENDKDVAMSFHYISMGDCIGWLEDFLMGMDSTLEPSAGAPLAMSSGTTQLRATATTLILCCLLIILPCFILPGI

Target ORF information:

RefSeq Version	XM_011535486.2
Organism	Homo sapiens(human)
Definition	Homo sapiens retinoic acid early transcript 1L (RAET1L), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535486.2

ORF Insert Sequence:

ATGGCAGCAG CCGCCATCCC AGCTTTGCTT CTGTGCCTCC CGCTTCTGTT CCTGCTGTTC 
GGCTGGTCCC GGGCTAGGCG AGACGACCCT CACTCTCTTT GCTATGACAT CACCGTCATC 
CCTAAGTTCA GACCTGGACC ACGGTGGTGT GCGGTTCAAG GCCAGGTGGA TGAAAAGACT 
TTTCTTCACT ATGACTGTGG CAACAAGACA GTCACACCCG TCAGTCCCCT GGGGAAGAAA 
CTAAATGTCA CAATGGCCTG GAAAGCACAG AACCCAGTAC TGAGAGAGGT GGTGGACATA 
CTTACAGAGC AACTGCTTGA CATTCAGCTG GAGAATTACA CACCCAAGGA ACCCCTCACC 
CTGCAGGCAA GGATGTCTTG TGAGCAGAAA GCTGAAGGAC ACAGCAGTGG ATCTTGGCAG 
TTCAGTATCG ATGGACAGAC CTTCCTACTC TTTGACTCAG AGAAGAGAAT GTGGACAACG 
GTTCATCCTG GAGCCAGAAA GATGAAAGAA AAGTGGGAGA ATGACAAGGA TGTGGCCATG 
TCCTTCCATT ACATCTCAAT GGGAGACTGC ATAGGATGGC TTGAGGACTT CTTGATGGGC 
ATGGACAGCA CCCTGGAGCC AAGTGCAGGA GCACCACTCG CCATGTCCTC AGGCACAACC 
CAACTCAGGG CCACAGCCAC CACCCTCATC CTTTGCTGCC TCCTCATCAT CCTCCCCTGC 
TTCATCCTCC CTGGCATCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A disease-linked
Science signaling10(481)(2017 May)
Zuo J,Willcox CR,Mohammed F,Davey M,Hunter S,Khan K,Antoun A,Katakia P,Croudace J,Inman C,Parry H,Briggs D,Malladi R,Willcox BE,Moss P

Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.
Clinical cancer research : an official journal of the American Association for Cancer Research20(22)5733-44(2014 Nov)
Wennerberg E,Pfefferle A,Ekblad L,Yoshimoto Y,Kremer V,Kaminskyy VO,Juhlin CC,H??g A,Bodin I,Svjatoha V,Larsson C,Zedenius J,Wennerberg J,Lundqvist A

The genotype of RAET1L (ULBP6), a ligand for human NKG2D (KLRK1), markedly influences the clinical outcome of allogeneic stem cell transplantation.
British journal of haematology159(5)589-98(2012 Dec)
Antoun A,Vekaria D,Salama RA,Pratt G,Jobson S,Cook M,Briggs D,Moss P

Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.
Human immunology71(6)610-20(2010 Jun)
Antoun A,Jobson S,Cook M,O'Callaghan CA,Moss P,Briggs DC

New genetic associations detected in a host response study to hepatitis B vaccine.
Genes and immunity11(3)232-8(2010 Apr)
Davila S,Froeling FE,Tan A,Bonnard C,Boland GJ,Snippe H,Hibberd ML,Seielstad M

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RAET1L cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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