LRFN5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LRFN5
Entrez Gene ID	145581
Full Name	leucine rich repeat and fibronectin type III domain containing 5
Synonyms	C14orf146,FIGLER8,SALM5
General protein information	Preferred Names leucine rich repeat and fibronectin type III domain containing 5 Names leucine-rich repeat and fibronectin type-III domain-containing protein 5 fibronectin type III, immunoglobulin and leucine rich repeat domains 8
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q21.1
Summary	This gene encodes a protein that belongs to the leucine-rich repeat and fibronectin type III domain-containing family of proteins. A similar protein in mouse, a glycosylated transmembrane protein, is thought to function in presynaptic differentiation. [provided by RefSeq, Sep 2016].
Disorder MIM:	612811

mRNA and Protein(s)

mRNA	Protein	Name
NM_001346173.1	NP_001333102.1	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 1 precursor
XM_017021048.1	XP_016876537.1	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform X1
NM_001346175.1	NP_001333104.1	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 2 precursor
NM_001330106.1	NP_001317035.1	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 2 precursor
NM_152447.4	NP_689660.2	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 1 precursor

Pathways from BioSystems

Homologies

	LRFN5	XP_001094064.1
Rattus norvegicus (Norway rat)	Lrfn5	NP_001101494.1
Gallus gallus (chicken)	LRFN5	XP_004936591.1
Homo sapiens (human)	LRFN5	NP_689660.2
Pan troglodytes (chimpanzee)	LRFN5	XP_001149289.1
Canis lupus familiaris (dog)	LOC490666	XP_005623411.1
Danio rerio (zebrafish)	si:ch73-206h2.1	XP_001921674.1
Xenopus tropicalis (tropical clawed frog)	lrfn5	XP_002941802.1
Mus musculus (house mouse)	Lrfn5	NP_848829.2

Gene Ontology
Bibliography

Related articles in PubMed

Structural basis of trans-synaptic interactions between PTP? and SALMs for inducing synapse formation.
Goto-Ito S, Yamagata A, Sato Y, Uemura T, Shiroshima T, Maeda A, Imai A, Mori H, Yoshida T, Fukai S
Nature communications9(1)269(2018 Jan)

Structural basis of SALM5-induced PTP? dimerization for synaptic differentiation.
Lin Z, Liu J, Ding H, Xu F, Liu H
Nature communications9(1)268(2018 Jan)

Neuron-specific SALM5 limits inflammation in the CNS via its interaction with HVEM.
Zhu Y, Yao S, Augustine MM, Xu H, Wang J, Sun J, Broadwater M, Ruff W, Luo L, Zhu G, Tamada K, Chen L
Science advances2(4)e1500637(2016 Apr)

Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval.
Avery CL, Sitlani CM, Arking DE, Arnett DK, Bis JC, Boerwinkle E, Buckley BM, Ida Chen YD, de Craen AJ, Eijgelsheim M, Enquobahrie D, Evans DS, Ford I, Garcia ME, Gudnason V, Harris TB, Heckbert SR, Hochner H, Hofman A, Hsueh WC, Isaacs A, Jukema JW, Knekt P, Kors JA, Krijthe BP, Kristiansson K, Laaksonen M, Liu Y, Li X, Macfarlane PW, Newton-Cheh C, Nieminen MS, Oostra BA, Peloso GM, Porthan K, Rice K, Rivadeneira FF, Rotter JI, Salomaa V, Sattar N, Siscovick DS, Slagboom PE, Smith AV, Sotoodehnia N, Stott DJ, Stricker BH, St?rmer T, Trompet S, Uitterlinden AG, van Duijn C, Westendorp RG, Witteman JC, Whitsel EA, Psaty BM
The pharmacogenomics journal14(1)6-13(2014 Feb)

Genome wide association study for plasma levels of natural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA project.
Oudot-Mellakh T, Cohen W, Germain M, Saut N, Kallel C, Zelenika D, Lathrop M, Tr?gou?t DA, Morange PE
British journal of haematology157(2)230-9(2012 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SALM5/Lrfn5, has recently been implicated in severe progressive autism and familial schizophrenia, pointing to the clinical importance of SALMs.[review]
Title: The SALM/Lrfn family of leucine-rich repeat-containing cell adhesion molecules.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Expression of SALM family proteins SALM3 and SALM5 in nonneural and neural cells induces both excitatory and inhibitory presynaptic differentiation in contacting axons.
Title: Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation.

The following LRFN5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRFN5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu47555	NM_001346175.1 Latest version!	Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu47555	NM_001330106.1 Latest version!	Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu31507	NM_001346173.1 Latest version!	Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu31507	NM_152447.4 Latest version!	Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu31507	XM_017021048.1 Latest version!	Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LRFN5 ( NM_001346175.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001333104.1 Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu47555
Clone ID Related Accession (Same CDS sequence)	NM_001346175.1 , NM_001330106.1
Accession Version	NM_001346175.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1401bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL121821.7, AL138498.5 and AW013887.1. On Sep 30, 2016 this sequence version replaced XM_017021050.1. Transcript Variant: This variant (4) differs in the 5' UTR, and lacks an alternate exon in the 3' coding region resulting in a frameshift, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Variants 2 and 4 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.91572.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153733, SAMN03465403 [ECO:0000348] ##Evidence-Data-END##

ATGGAAAAAA TTCTTTTTTA TCTGTTTCTC ATTGGCATAG CAGTGAAAGC TCAGATCTGT 
CCAAAGCGTT GTGTCTGTCA GATTTTGTCT CCTAATCTTG CAACCCTTTG TGCCAAGAAA 
GGGCTTTTAT TTGTTCCACC AAACATTGAC AGAAGAACTG TGGAACTGCG GTTGGCAGAC 
AATTTTGTTA CAAATATTAA AAGGAAAGAT TTTGCCAATA TGACCAGCTT GGTGGACCTG 
ACTCTATCCA GGAATACAAT AAGTTTTATT ACACCTCATG CTTTCGCTGA CCTACGAAAT 
TTGAGGGCTT TGCATTTGAA TAGCAACAGA TTGACTAAAA TTACAAATGA TATGTTCAGT 
GGTCTTTCCA ATCTTCATCA TTTGATACTG AACAACAATC AGCTGACTTT AATTTCCTCT 
ACAGCGTTTG ATGATGTCTT CGCCCTTGAG GAGCTGGATC TGTCCTATAA TAATCTAGAA 
ACCATTCCTT GGGATGCTGT TGAGAAGATG GTTAGCTTGC ATACCCTTAG TTTGGATCAC 
AATATGATTG ATAACATTCC TAAGGGGACC TTCTCCCATT TGCACAAGAT GACTCGGTTA 
GATGTGACAT CAAATAAATT GCAGAAGCTA CCACCTGACC CTCTCTTTCA GCGAGCTCAG 
GTACTAGCAA CCTCAGGAAT CATAAGCCCA TCTACTTTTG CATTAAGTTT TGGTGGAAAC 
CCCTTGCATT GCAATTGTGA ATTGTTGTGG TTGAGGCGTC TGTCCAGAGA AGATGACTTA 
GAGACCTGTG CTTCTCCTCC ACTTTTAACT GGCCGCTACT TTTGGTCAAT TCCTGAAGAA 
GAGTTTTTGT GTGAGCCTCC TCTCATTACT CGTCATACAC ATGAGATGAG AGTCCTGGAG 
GGACAAAGGG CAACACTGAG GTGCAAAGCC AGGGGAGACC CTGAGCCTGC AATTCACTGG 
ATTTCTCCTG AAGGGAAGCT TATTTCAAAT GCAACAAGAT CTCTGGTGTA TGATAACGGA 
ACACTTGACA TTCTTATCAC AACTGTAAAG GATACAGGTG CTTTTACCTG CATTGCTTCC 
AATCCTGCTG GGGAAGCAAC ACAAATAGTG GATCTTCATA TAATTAAGCT CCCTCACTTA 
CTAAATAGTA CAAACCATAT CCATGAGCCT GATCCTGGTT CTTCAGATAT CTCAACTTCT 
ACCAAGTCAG GTTCTAATAC AAGCAGTAGT AATGGTGATA CTAAATTGAG TCAAGATAAA 
ATTGTGGTGG CAGAAGCTAC ATCATCAACG GCACTACTTA AATTTAATTT TCAAAGAAAT 
ATCCCTGGAA TACGTATGTT TCAAATCCAG TACAATGGTA CTTATGATGA CACCCTTGTT 
TACAGATGCT TTGCTGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001333104.1
CDS	1728..3128
Translation	MEKILFYLFLIGIAVKAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHIIKLPHLLNSTNHIHEPDPGSSDISTSTKSGSNTSSSNGDTKLSQDKIVVAEATSSTALLKFNFQRNIPGIRMFQIQYNGTYDDTLVYRCFAD

Target ORF information:

RefSeq Version	NM_001346175.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001346175.1

ORF Insert Sequence:

ATGGAAAAAA TTCTTTTTTA TCTGTTTCTC ATTGGCATAG CAGTGAAAGC TCAGATCTGT 
CCAAAGCGTT GTGTCTGTCA GATTTTGTCT CCTAATCTTG CAACCCTTTG TGCCAAGAAA 
GGGCTTTTAT TTGTTCCACC AAACATTGAC AGAAGAACTG TGGAACTGCG GTTGGCAGAC 
AATTTTGTTA CAAATATTAA AAGGAAAGAT TTTGCCAATA TGACCAGCTT GGTGGACCTG 
ACTCTATCCA GGAATACAAT AAGTTTTATT ACACCTCATG CTTTCGCTGA CCTACGAAAT 
TTGAGGGCTT TGCATTTGAA TAGCAACAGA TTGACTAAAA TTACAAATGA TATGTTCAGT 
GGTCTTTCCA ATCTTCATCA TTTGATACTG AACAACAATC AGCTGACTTT AATTTCCTCT 
ACAGCGTTTG ATGATGTCTT CGCCCTTGAG GAGCTGGATC TGTCCTATAA TAATCTAGAA 
ACCATTCCTT GGGATGCTGT TGAGAAGATG GTTAGCTTGC ATACCCTTAG TTTGGATCAC 
AATATGATTG ATAACATTCC TAAGGGGACC TTCTCCCATT TGCACAAGAT GACTCGGTTA 
GATGTGACAT CAAATAAATT GCAGAAGCTA CCACCTGACC CTCTCTTTCA GCGAGCTCAG 
GTACTAGCAA CCTCAGGAAT CATAAGCCCA TCTACTTTTG CATTAAGTTT TGGTGGAAAC 
CCCTTGCATT GCAATTGTGA ATTGTTGTGG TTGAGGCGTC TGTCCAGAGA AGATGACTTA 
GAGACCTGTG CTTCTCCTCC ACTTTTAACT GGCCGCTACT TTTGGTCAAT TCCTGAAGAA 
GAGTTTTTGT GTGAGCCTCC TCTCATTACT CGTCATACAC ATGAGATGAG AGTCCTGGAG 
GGACAAAGGG CAACACTGAG GTGCAAAGCC AGGGGAGACC CTGAGCCTGC AATTCACTGG 
ATTTCTCCTG AAGGGAAGCT TATTTCAAAT GCAACAAGAT CTCTGGTGTA TGATAACGGA 
ACACTTGACA TTCTTATCAC AACTGTAAAG GATACAGGTG CTTTTACCTG CATTGCTTCC 
AATCCTGCTG GGGAAGCAAC ACAAATAGTG GATCTTCATA TAATTAAGCT CCCTCACTTA 
CTAAATAGTA CAAACCATAT CCATGAGCCT GATCCTGGTT CTTCAGATAT CTCAACTTCT 
ACCAAGTCAG GTTCTAATAC AAGCAGTAGT AATGGTGATA CTAAATTGAG TCAAGATAAA 
ATTGTGGTGG CAGAAGCTAC ATCATCAACG GCACTACTTA AATTTAATTT TCAAAGAAAT 
ATCCCTGGAA TACGTATGTT TCAAATCCAG TACAATGGTA CTTATGATGA CACCCTTGTT 
TACAGATGCT TTGCTGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRFN5 ( NM_001330106.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317035.1 Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu47555
Clone ID Related Accession (Same CDS sequence)	NM_001346175.1 , NM_001330106.1
Accession Version	NM_001330106.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1401bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL121821.7, AL109662.3, AL138498.5 and AW013887.1. On Aug 17, 2016 this sequence version replaced XM_005267369.3. Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region resulting in a frameshift compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Variants 2 and 4 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.162654.1, SRR1660803.174864.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAAAAA TTCTTTTTTA TCTGTTTCTC ATTGGCATAG CAGTGAAAGC TCAGATCTGT 
CCAAAGCGTT GTGTCTGTCA GATTTTGTCT CCTAATCTTG CAACCCTTTG TGCCAAGAAA 
GGGCTTTTAT TTGTTCCACC AAACATTGAC AGAAGAACTG TGGAACTGCG GTTGGCAGAC 
AATTTTGTTA CAAATATTAA AAGGAAAGAT TTTGCCAATA TGACCAGCTT GGTGGACCTG 
ACTCTATCCA GGAATACAAT AAGTTTTATT ACACCTCATG CTTTCGCTGA CCTACGAAAT 
TTGAGGGCTT TGCATTTGAA TAGCAACAGA TTGACTAAAA TTACAAATGA TATGTTCAGT 
GGTCTTTCCA ATCTTCATCA TTTGATACTG AACAACAATC AGCTGACTTT AATTTCCTCT 
ACAGCGTTTG ATGATGTCTT CGCCCTTGAG GAGCTGGATC TGTCCTATAA TAATCTAGAA 
ACCATTCCTT GGGATGCTGT TGAGAAGATG GTTAGCTTGC ATACCCTTAG TTTGGATCAC 
AATATGATTG ATAACATTCC TAAGGGGACC TTCTCCCATT TGCACAAGAT GACTCGGTTA 
GATGTGACAT CAAATAAATT GCAGAAGCTA CCACCTGACC CTCTCTTTCA GCGAGCTCAG 
GTACTAGCAA CCTCAGGAAT CATAAGCCCA TCTACTTTTG CATTAAGTTT TGGTGGAAAC 
CCCTTGCATT GCAATTGTGA ATTGTTGTGG TTGAGGCGTC TGTCCAGAGA AGATGACTTA 
GAGACCTGTG CTTCTCCTCC ACTTTTAACT GGCCGCTACT TTTGGTCAAT TCCTGAAGAA 
GAGTTTTTGT GTGAGCCTCC TCTCATTACT CGTCATACAC ATGAGATGAG AGTCCTGGAG 
GGACAAAGGG CAACACTGAG GTGCAAAGCC AGGGGAGACC CTGAGCCTGC AATTCACTGG 
ATTTCTCCTG AAGGGAAGCT TATTTCAAAT GCAACAAGAT CTCTGGTGTA TGATAACGGA 
ACACTTGACA TTCTTATCAC AACTGTAAAG GATACAGGTG CTTTTACCTG CATTGCTTCC 
AATCCTGCTG GGGAAGCAAC ACAAATAGTG GATCTTCATA TAATTAAGCT CCCTCACTTA 
CTAAATAGTA CAAACCATAT CCATGAGCCT GATCCTGGTT CTTCAGATAT CTCAACTTCT 
ACCAAGTCAG GTTCTAATAC AAGCAGTAGT AATGGTGATA CTAAATTGAG TCAAGATAAA 
ATTGTGGTGG CAGAAGCTAC ATCATCAACG GCACTACTTA AATTTAATTT TCAAAGAAAT 
ATCCCTGGAA TACGTATGTT TCAAATCCAG TACAATGGTA CTTATGATGA CACCCTTGTT 
TACAGATGCT TTGCTGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317035.1
CDS	1904..3304
Translation	MEKILFYLFLIGIAVKAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHIIKLPHLLNSTNHIHEPDPGSSDISTSTKSGSNTSSSNGDTKLSQDKIVVAEATSSTALLKFNFQRNIPGIRMFQIQYNGTYDDTLVYRCFAD

Target ORF information:

RefSeq Version	NM_001330106.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330106.1

ORF Insert Sequence:

ATGGAAAAAA TTCTTTTTTA TCTGTTTCTC ATTGGCATAG CAGTGAAAGC TCAGATCTGT 
CCAAAGCGTT GTGTCTGTCA GATTTTGTCT CCTAATCTTG CAACCCTTTG TGCCAAGAAA 
GGGCTTTTAT TTGTTCCACC AAACATTGAC AGAAGAACTG TGGAACTGCG GTTGGCAGAC 
AATTTTGTTA CAAATATTAA AAGGAAAGAT TTTGCCAATA TGACCAGCTT GGTGGACCTG 
ACTCTATCCA GGAATACAAT AAGTTTTATT ACACCTCATG CTTTCGCTGA CCTACGAAAT 
TTGAGGGCTT TGCATTTGAA TAGCAACAGA TTGACTAAAA TTACAAATGA TATGTTCAGT 
GGTCTTTCCA ATCTTCATCA TTTGATACTG AACAACAATC AGCTGACTTT AATTTCCTCT 
ACAGCGTTTG ATGATGTCTT CGCCCTTGAG GAGCTGGATC TGTCCTATAA TAATCTAGAA 
ACCATTCCTT GGGATGCTGT TGAGAAGATG GTTAGCTTGC ATACCCTTAG TTTGGATCAC 
AATATGATTG ATAACATTCC TAAGGGGACC TTCTCCCATT TGCACAAGAT GACTCGGTTA 
GATGTGACAT CAAATAAATT GCAGAAGCTA CCACCTGACC CTCTCTTTCA GCGAGCTCAG 
GTACTAGCAA CCTCAGGAAT CATAAGCCCA TCTACTTTTG CATTAAGTTT TGGTGGAAAC 
CCCTTGCATT GCAATTGTGA ATTGTTGTGG TTGAGGCGTC TGTCCAGAGA AGATGACTTA 
GAGACCTGTG CTTCTCCTCC ACTTTTAACT GGCCGCTACT TTTGGTCAAT TCCTGAAGAA 
GAGTTTTTGT GTGAGCCTCC TCTCATTACT CGTCATACAC ATGAGATGAG AGTCCTGGAG 
GGACAAAGGG CAACACTGAG GTGCAAAGCC AGGGGAGACC CTGAGCCTGC AATTCACTGG 
ATTTCTCCTG AAGGGAAGCT TATTTCAAAT GCAACAAGAT CTCTGGTGTA TGATAACGGA 
ACACTTGACA TTCTTATCAC AACTGTAAAG GATACAGGTG CTTTTACCTG CATTGCTTCC 
AATCCTGCTG GGGAAGCAAC ACAAATAGTG GATCTTCATA TAATTAAGCT CCCTCACTTA 
CTAAATAGTA CAAACCATAT CCATGAGCCT GATCCTGGTT CTTCAGATAT CTCAACTTCT 
ACCAAGTCAG GTTCTAATAC AAGCAGTAGT AATGGTGATA CTAAATTGAG TCAAGATAAA 
ATTGTGGTGG CAGAAGCTAC ATCATCAACG GCACTACTTA AATTTAATTT TCAAAGAAAT 
ATCCCTGGAA TACGTATGTT TCAAATCCAG TACAATGGTA CTTATGATGA CACCCTTGTT 
TACAGATGCT TTGCTGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRFN5 ( NM_001346173.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001333102.1 Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu31507
Clone ID Related Accession (Same CDS sequence)	NM_001346173.1 , XM_017021048.1 , NM_152447.4
Accession Version	NM_001346173.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2160bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL121821.7, AL138498.5 and AW013887.1. On Sep 30, 2016 this sequence version replaced XM_017021049.1. Transcript Variant: This variant (3) differs in the 5' UTR comapred to variant 1. Variants 1 and 3 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.16367.1, SRR1803613.264872.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153031, SAMEA2153733 [ECO:0000348] ##Evidence-Data-END##

ATGGAAAAAA TTCTTTTTTA TCTGTTTCTC ATTGGCATAG CAGTGAAAGC TCAGATCTGT 
CCAAAGCGTT GTGTCTGTCA GATTTTGTCT CCTAATCTTG CAACCCTTTG TGCCAAGAAA 
GGGCTTTTAT TTGTTCCACC AAACATTGAC AGAAGAACTG TGGAACTGCG GTTGGCAGAC 
AATTTTGTTA CAAATATTAA AAGGAAAGAT TTTGCCAATA TGACCAGCTT GGTGGACCTG 
ACTCTATCCA GGAATACAAT AAGTTTTATT ACACCTCATG CTTTCGCTGA CCTACGAAAT 
TTGAGGGCTT TGCATTTGAA TAGCAACAGA TTGACTAAAA TTACAAATGA TATGTTCAGT 
GGTCTTTCCA ATCTTCATCA TTTGATACTG AACAACAATC AGCTGACTTT AATTTCCTCT 
ACAGCGTTTG ATGATGTCTT CGCCCTTGAG GAGCTGGATC TGTCCTATAA TAATCTAGAA 
ACCATTCCTT GGGATGCTGT TGAGAAGATG GTTAGCTTGC ATACCCTTAG TTTGGATCAC 
AATATGATTG ATAACATTCC TAAGGGGACC TTCTCCCATT TGCACAAGAT GACTCGGTTA 
GATGTGACAT CAAATAAATT GCAGAAGCTA CCACCTGACC CTCTCTTTCA GCGAGCTCAG 
GTACTAGCAA CCTCAGGAAT CATAAGCCCA TCTACTTTTG CATTAAGTTT TGGTGGAAAC 
CCCTTGCATT GCAATTGTGA ATTGTTGTGG TTGAGGCGTC TGTCCAGAGA AGATGACTTA 
GAGACCTGTG CTTCTCCTCC ACTTTTAACT GGCCGCTACT TTTGGTCAAT TCCTGAAGAA 
GAGTTTTTGT GTGAGCCTCC TCTCATTACT CGTCATACAC ATGAGATGAG AGTCCTGGAG 
GGACAAAGGG CAACACTGAG GTGCAAAGCC AGGGGAGACC CTGAGCCTGC AATTCACTGG 
ATTTCTCCTG AAGGGAAGCT TATTTCAAAT GCAACAAGAT CTCTGGTGTA TGATAACGGA 
ACACTTGACA TTCTTATCAC AACTGTAAAG GATACAGGTG CTTTTACCTG CATTGCTTCC 
AATCCTGCTG GGGAAGCAAC ACAAATAGTG GATCTTCATA TAATTAAGCT CCCTCACTTA 
CTAAATAGTA CAAACCATAT CCATGAGCCT GATCCTGGTT CTTCAGATAT CTCAACTTCT 
ACCAAGTCAG GTTCTAATAC AAGCAGTAGT AATGGTGATA CTAAATTGAG TCAAGATAAA 
ATTGTGGTGG CAGAAGCTAC ATCATCAACG GCACTACTTA AATTTAATTT TCAAAGAAAT 
ATCCCTGGAA TACGTATGTT TCAAATCCAG TACAATGGTA CTTATGATGA CACCCTTGTT 
TACAGAATGA TACCTCCTAC GAGCAAAACT TTTCTGGTCA ATAATCTGGC TGCTGGAACT 
ATGTATGACT TGTGTGTCTT GGCCATATAT GATGATGGCA TCACTTCCCT CACTGCCACA 
AGAGTCGTGG GTTGCATCCA GTTTACTACG GAACAGGATT ATGTGCGTTG CCATTTCATG 
CAGTCTCAGT TTTTGGGAGG CACCATGATT ATTATTATTG GTGGAATCAT TGTAGCATCT 
GTGCTGGTAT TCATCATTAT TCTGATGATC CGGTATAAGG TTTGCAACAA TAATGGGCAA 
CACAAGGTCA CCAAGGTTAG CAATGTTTAT TCCCAAACTA ACGGGGCTCA AATACAAGGC 
TGTAGTGTAA CGCTGCCCCA GTCCGTGTCC AAACAAGCTG TGGGACACGA AGAGAATGCC 
CAGTGTTGTA AAGCTACCAG TGACAATGTG ATTCAATCTT CAGAAACTTG TTCGAGTCAG 
GACTCCTCTA CCACTACCTC TGCTTTGCCT CCTTCCTGGA CTTCAAGCAC TTCTGTGTCC 
CAAAAGCAGA AAAGAAAGAC TGGCACAAAG CCAAGTACAG AACCACAGAA TGAAGCCGTC 
ACAAATGTTG AATCCCAAAA CACTAACAGG AACAACTCAA CTGCCTTGCA GTTAGCTAGC 
CGTCCTCCCG ATTCTGTCAC AGAGGGGCCC ACGTCTAAAA GAGCACATAT AAAGCCAAAT 
GCTTTGCTGA CTAATGTTGA CCAGATTGTC CAGGAAACAC AGAGGCTGGA GTTAATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001333102.1
CDS	1728..3887
Translation	MEKILFYLFLIGIAVKAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHIIKLPHLLNSTNHIHEPDPGSSDISTSTKSGSNTSSSNGDTKLSQDKIVVAEATSSTALLKFNFQRNIPGIRMFQIQYNGTYDDTLVYRMIPPTSKTFLVNNLAAGTMYDLCVLAIYDDGITSLTATRVVGCIQFTTEQDYVRCHFMQSQFLGGTMIIIIGGIIVASVLVFIIILMIRYKVCNNNGQHKVTKVSNVYSQTNGAQIQGCSVTLPQSVSKQAVGHEENAQCCKATSDNVIQSSETCSSQDSSTTTSALPPSWTSSTSVSQKQKRKTGTKPSTEPQNEAVTNVESQNTNRNNSTALQLASRPPDSVTEGPTSKRAHIKPNALLTNVDQIVQETQRLELI

Target ORF information:

RefSeq Version	NM_001346173.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001346173.1

ORF Insert Sequence:

ATGGAAAAAA TTCTTTTTTA TCTGTTTCTC ATTGGCATAG CAGTGAAAGC TCAGATCTGT 
CCAAAGCGTT GTGTCTGTCA GATTTTGTCT CCTAATCTTG CAACCCTTTG TGCCAAGAAA 
GGGCTTTTAT TTGTTCCACC AAACATTGAC AGAAGAACTG TGGAACTGCG GTTGGCAGAC 
AATTTTGTTA CAAATATTAA AAGGAAAGAT TTTGCCAATA TGACCAGCTT GGTGGACCTG 
ACTCTATCCA GGAATACAAT AAGTTTTATT ACACCTCATG CTTTCGCTGA CCTACGAAAT 
TTGAGGGCTT TGCATTTGAA TAGCAACAGA TTGACTAAAA TTACAAATGA TATGTTCAGT 
GGTCTTTCCA ATCTTCATCA TTTGATACTG AACAACAATC AGCTGACTTT AATTTCCTCT 
ACAGCGTTTG ATGATGTCTT CGCCCTTGAG GAGCTGGATC TGTCCTATAA TAATCTAGAA 
ACCATTCCTT GGGATGCTGT TGAGAAGATG GTTAGCTTGC ATACCCTTAG TTTGGATCAC 
AATATGATTG ATAACATTCC TAAGGGGACC TTCTCCCATT TGCACAAGAT GACTCGGTTA 
GATGTGACAT CAAATAAATT GCAGAAGCTA CCACCTGACC CTCTCTTTCA GCGAGCTCAG 
GTACTAGCAA CCTCAGGAAT CATAAGCCCA TCTACTTTTG CATTAAGTTT TGGTGGAAAC 
CCCTTGCATT GCAATTGTGA ATTGTTGTGG TTGAGGCGTC TGTCCAGAGA AGATGACTTA 
GAGACCTGTG CTTCTCCTCC ACTTTTAACT GGCCGCTACT TTTGGTCAAT TCCTGAAGAA 
GAGTTTTTGT GTGAGCCTCC TCTCATTACT CGTCATACAC ATGAGATGAG AGTCCTGGAG 
GGACAAAGGG CAACACTGAG GTGCAAAGCC AGGGGAGACC CTGAGCCTGC AATTCACTGG 
ATTTCTCCTG AAGGGAAGCT TATTTCAAAT GCAACAAGAT CTCTGGTGTA TGATAACGGA 
ACACTTGACA TTCTTATCAC AACTGTAAAG GATACAGGTG CTTTTACCTG CATTGCTTCC 
AATCCTGCTG GGGAAGCAAC ACAAATAGTG GATCTTCATA TAATTAAGCT CCCTCACTTA 
CTAAATAGTA CAAACCATAT CCATGAGCCT GATCCTGGTT CTTCAGATAT CTCAACTTCT 
ACCAAGTCAG GTTCTAATAC AAGCAGTAGT AATGGTGATA CTAAATTGAG TCAAGATAAA 
ATTGTGGTGG CAGAAGCTAC ATCATCAACG GCACTACTTA AATTTAATTT TCAAAGAAAT 
ATCCCTGGAA TACGTATGTT TCAAATCCAG TACAATGGTA CTTATGATGA CACCCTTGTT 
TACAGAATGA TACCTCCTAC GAGCAAAACT TTTCTGGTCA ATAATCTGGC TGCTGGAACT 
ATGTATGACT TGTGTGTCTT GGCCATATAT GATGATGGCA TCACTTCCCT CACTGCCACA 
AGAGTCGTGG GTTGCATCCA GTTTACTACG GAACAGGATT ATGTGCGTTG CCATTTCATG 
CAGTCTCAGT TTTTGGGAGG CACCATGATT ATTATTATTG GTGGAATCAT TGTAGCATCT 
GTGCTGGTAT TCATCATTAT TCTGATGATC CGGTATAAGG TTTGCAACAA TAATGGGCAA 
CACAAGGTCA CCAAGGTTAG CAATGTTTAT TCCCAAACTA ACGGGGCTCA AATACAAGGC 
TGTAGTGTAA CGCTGCCCCA GTCCGTGTCC AAACAAGCTG TGGGACACGA AGAGAATGCC 
CAGTGTTGTA AAGCTACCAG TGACAATGTG ATTCAATCTT CAGAAACTTG TTCGAGTCAG 
GACTCCTCTA CCACTACCTC TGCTTTGCCT CCTTCCTGGA CTTCAAGCAC TTCTGTGTCC 
CAAAAGCAGA AAAGAAAGAC TGGCACAAAG CCAAGTACAG AACCACAGAA TGAAGCCGTC 
ACAAATGTTG AATCCCAAAA CACTAACAGG AACAACTCAA CTGCCTTGCA GTTAGCTAGC 
CGTCCTCCCG ATTCTGTCAC AGAGGGGCCC ACGTCTAAAA GAGCACATAT AAAGCCAAAT 
GCTTTGCTGA CTAATGTTGA CCAGATTGTC CAGGAAACAC AGAGGCTGGA GTTAATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRFN5 ( NM_152447.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_689660.2 Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 1, mRNA.

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CloneID	OHu31507
Clone ID Related Accession (Same CDS sequence)	NM_001346173.1 , XM_017021048.1 , NM_152447.4
Accession Version	NM_152447.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2160bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL121821.7, DA096504.1, AK096627.1, BC043165.1, AL138498.5 and AW013887.1. This sequence is a reference standard in the RefSeqGene project. On Sep 30, 2016 this sequence version replaced NM_152447.3. Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1 and 3 encode the same isoform. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.226538.1, SRR1803617.20021.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGAAAAAA TTCTTTTTTA TCTGTTTCTC ATTGGCATAG CAGTGAAAGC TCAGATCTGT 
CCAAAGCGTT GTGTCTGTCA GATTTTGTCT CCTAATCTTG CAACCCTTTG TGCCAAGAAA 
GGGCTTTTAT TTGTTCCACC AAACATTGAC AGAAGAACTG TGGAACTGCG GTTGGCAGAC 
AATTTTGTTA CAAATATTAA AAGGAAAGAT TTTGCCAATA TGACCAGCTT GGTGGACCTG 
ACTCTATCCA GGAATACAAT AAGTTTTATT ACACCTCATG CTTTCGCTGA CCTACGAAAT 
TTGAGGGCTT TGCATTTGAA TAGCAACAGA TTGACTAAAA TTACAAATGA TATGTTCAGT 
GGTCTTTCCA ATCTTCATCA TTTGATACTG AACAACAATC AGCTGACTTT AATTTCCTCT 
ACAGCGTTTG ATGATGTCTT CGCCCTTGAG GAGCTGGATC TGTCCTATAA TAATCTAGAA 
ACCATTCCTT GGGATGCTGT TGAGAAGATG GTTAGCTTGC ATACCCTTAG TTTGGATCAC 
AATATGATTG ATAACATTCC TAAGGGGACC TTCTCCCATT TGCACAAGAT GACTCGGTTA 
GATGTGACAT CAAATAAATT GCAGAAGCTA CCACCTGACC CTCTCTTTCA GCGAGCTCAG 
GTACTAGCAA CCTCAGGAAT CATAAGCCCA TCTACTTTTG CATTAAGTTT TGGTGGAAAC 
CCCTTGCATT GCAATTGTGA ATTGTTGTGG TTGAGGCGTC TGTCCAGAGA AGATGACTTA 
GAGACCTGTG CTTCTCCTCC ACTTTTAACT GGCCGCTACT TTTGGTCAAT TCCTGAAGAA 
GAGTTTTTGT GTGAGCCTCC TCTCATTACT CGTCATACAC ATGAGATGAG AGTCCTGGAG 
GGACAAAGGG CAACACTGAG GTGCAAAGCC AGGGGAGACC CTGAGCCTGC AATTCACTGG 
ATTTCTCCTG AAGGGAAGCT TATTTCAAAT GCAACAAGAT CTCTGGTGTA TGATAACGGA 
ACACTTGACA TTCTTATCAC AACTGTAAAG GATACAGGTG CTTTTACCTG CATTGCTTCC 
AATCCTGCTG GGGAAGCAAC ACAAATAGTG GATCTTCATA TAATTAAGCT CCCTCACTTA 
CTAAATAGTA CAAACCATAT CCATGAGCCT GATCCTGGTT CTTCAGATAT CTCAACTTCT 
ACCAAGTCAG GTTCTAATAC AAGCAGTAGT AATGGTGATA CTAAATTGAG TCAAGATAAA 
ATTGTGGTGG CAGAAGCTAC ATCATCAACG GCACTACTTA AATTTAATTT TCAAAGAAAT 
ATCCCTGGAA TACGTATGTT TCAAATCCAG TACAATGGTA CTTATGATGA CACCCTTGTT 
TACAGAATGA TACCTCCTAC GAGCAAAACT TTTCTGGTCA ATAATCTGGC TGCTGGAACT 
ATGTATGACT TGTGTGTCTT GGCCATATAT GATGATGGCA TCACTTCCCT CACTGCCACA 
AGAGTCGTGG GTTGCATCCA GTTTACTACG GAACAGGATT ATGTGCGTTG CCATTTCATG 
CAGTCTCAGT TTTTGGGAGG CACCATGATT ATTATTATTG GTGGAATCAT TGTAGCATCT 
GTGCTGGTAT TCATCATTAT TCTGATGATC CGGTATAAGG TTTGCAACAA TAATGGGCAA 
CACAAGGTCA CCAAGGTTAG CAATGTTTAT TCCCAAACTA ACGGGGCTCA AATACAAGGC 
TGTAGTGTAA CGCTGCCCCA GTCCGTGTCC AAACAAGCTG TGGGACACGA AGAGAATGCC 
CAGTGTTGTA AAGCTACCAG TGACAATGTG ATTCAATCTT CAGAAACTTG TTCGAGTCAG 
GACTCCTCTA CCACTACCTC TGCTTTGCCT CCTTCCTGGA CTTCAAGCAC TTCTGTGTCC 
CAAAAGCAGA AAAGAAAGAC TGGCACAAAG CCAAGTACAG AACCACAGAA TGAAGCCGTC 
ACAAATGTTG AATCCCAAAA CACTAACAGG AACAACTCAA CTGCCTTGCA GTTAGCTAGC 
CGTCCTCCCG ATTCTGTCAC AGAGGGGCCC ACGTCTAAAA GAGCACATAT AAAGCCAAAT 
GCTTTGCTGA CTAATGTTGA CCAGATTGTC CAGGAAACAC AGAGGCTGGA GTTAATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_689660.2
CDS	1904..4063
Translation	MEKILFYLFLIGIAVKAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHIIKLPHLLNSTNHIHEPDPGSSDISTSTKSGSNTSSSNGDTKLSQDKIVVAEATSSTALLKFNFQRNIPGIRMFQIQYNGTYDDTLVYRMIPPTSKTFLVNNLAAGTMYDLCVLAIYDDGITSLTATRVVGCIQFTTEQDYVRCHFMQSQFLGGTMIIIIGGIIVASVLVFIIILMIRYKVCNNNGQHKVTKVSNVYSQTNGAQIQGCSVTLPQSVSKQAVGHEENAQCCKATSDNVIQSSETCSSQDSSTTTSALPPSWTSSTSVSQKQKRKTGTKPSTEPQNEAVTNVESQNTNRNNSTALQLASRPPDSVTEGPTSKRAHIKPNALLTNVDQIVQETQRLELI

Target ORF information:

RefSeq Version	NM_152447.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152447.4

ORF Insert Sequence:

ATGGAAAAAA TTCTTTTTTA TCTGTTTCTC ATTGGCATAG CAGTGAAAGC TCAGATCTGT 
CCAAAGCGTT GTGTCTGTCA GATTTTGTCT CCTAATCTTG CAACCCTTTG TGCCAAGAAA 
GGGCTTTTAT TTGTTCCACC AAACATTGAC AGAAGAACTG TGGAACTGCG GTTGGCAGAC 
AATTTTGTTA CAAATATTAA AAGGAAAGAT TTTGCCAATA TGACCAGCTT GGTGGACCTG 
ACTCTATCCA GGAATACAAT AAGTTTTATT ACACCTCATG CTTTCGCTGA CCTACGAAAT 
TTGAGGGCTT TGCATTTGAA TAGCAACAGA TTGACTAAAA TTACAAATGA TATGTTCAGT 
GGTCTTTCCA ATCTTCATCA TTTGATACTG AACAACAATC AGCTGACTTT AATTTCCTCT 
ACAGCGTTTG ATGATGTCTT CGCCCTTGAG GAGCTGGATC TGTCCTATAA TAATCTAGAA 
ACCATTCCTT GGGATGCTGT TGAGAAGATG GTTAGCTTGC ATACCCTTAG TTTGGATCAC 
AATATGATTG ATAACATTCC TAAGGGGACC TTCTCCCATT TGCACAAGAT GACTCGGTTA 
GATGTGACAT CAAATAAATT GCAGAAGCTA CCACCTGACC CTCTCTTTCA GCGAGCTCAG 
GTACTAGCAA CCTCAGGAAT CATAAGCCCA TCTACTTTTG CATTAAGTTT TGGTGGAAAC 
CCCTTGCATT GCAATTGTGA ATTGTTGTGG TTGAGGCGTC TGTCCAGAGA AGATGACTTA 
GAGACCTGTG CTTCTCCTCC ACTTTTAACT GGCCGCTACT TTTGGTCAAT TCCTGAAGAA 
GAGTTTTTGT GTGAGCCTCC TCTCATTACT CGTCATACAC ATGAGATGAG AGTCCTGGAG 
GGACAAAGGG CAACACTGAG GTGCAAAGCC AGGGGAGACC CTGAGCCTGC AATTCACTGG 
ATTTCTCCTG AAGGGAAGCT TATTTCAAAT GCAACAAGAT CTCTGGTGTA TGATAACGGA 
ACACTTGACA TTCTTATCAC AACTGTAAAG GATACAGGTG CTTTTACCTG CATTGCTTCC 
AATCCTGCTG GGGAAGCAAC ACAAATAGTG GATCTTCATA TAATTAAGCT CCCTCACTTA 
CTAAATAGTA CAAACCATAT CCATGAGCCT GATCCTGGTT CTTCAGATAT CTCAACTTCT 
ACCAAGTCAG GTTCTAATAC AAGCAGTAGT AATGGTGATA CTAAATTGAG TCAAGATAAA 
ATTGTGGTGG CAGAAGCTAC ATCATCAACG GCACTACTTA AATTTAATTT TCAAAGAAAT 
ATCCCTGGAA TACGTATGTT TCAAATCCAG TACAATGGTA CTTATGATGA CACCCTTGTT 
TACAGAATGA TACCTCCTAC GAGCAAAACT TTTCTGGTCA ATAATCTGGC TGCTGGAACT 
ATGTATGACT TGTGTGTCTT GGCCATATAT GATGATGGCA TCACTTCCCT CACTGCCACA 
AGAGTCGTGG GTTGCATCCA GTTTACTACG GAACAGGATT ATGTGCGTTG CCATTTCATG 
CAGTCTCAGT TTTTGGGAGG CACCATGATT ATTATTATTG GTGGAATCAT TGTAGCATCT 
GTGCTGGTAT TCATCATTAT TCTGATGATC CGGTATAAGG TTTGCAACAA TAATGGGCAA 
CACAAGGTCA CCAAGGTTAG CAATGTTTAT TCCCAAACTA ACGGGGCTCA AATACAAGGC 
TGTAGTGTAA CGCTGCCCCA GTCCGTGTCC AAACAAGCTG TGGGACACGA AGAGAATGCC 
CAGTGTTGTA AAGCTACCAG TGACAATGTG ATTCAATCTT CAGAAACTTG TTCGAGTCAG 
GACTCCTCTA CCACTACCTC TGCTTTGCCT CCTTCCTGGA CTTCAAGCAC TTCTGTGTCC 
CAAAAGCAGA AAAGAAAGAC TGGCACAAAG CCAAGTACAG AACCACAGAA TGAAGCCGTC 
ACAAATGTTG AATCCCAAAA CACTAACAGG AACAACTCAA CTGCCTTGCA GTTAGCTAGC 
CGTCCTCCCG ATTCTGTCAC AGAGGGGCCC ACGTCTAAAA GAGCACATAT AAAGCCAAAT 
GCTTTGCTGA CTAATGTTGA CCAGATTGTC CAGGAAACAC AGAGGCTGGA GTTAATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRFN5 ( XM_017021048.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016876537.1 Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant X1, mRNA.

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CloneID	OHu31507
Clone ID Related Accession (Same CDS sequence)	NM_001346173.1 , XM_017021048.1 , NM_152447.4
Accession Version	XM_017021048.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2160bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat and fibronectin type-III domain-containing protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000014.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAAAAA TTCTTTTTTA TCTGTTTCTC ATTGGCATAG CAGTGAAAGC TCAGATCTGT 
CCAAAGCGTT GTGTCTGTCA GATTTTGTCT CCTAATCTTG CAACCCTTTG TGCCAAGAAA 
GGGCTTTTAT TTGTTCCACC AAACATTGAC AGAAGAACTG TGGAACTGCG GTTGGCAGAC 
AATTTTGTTA CAAATATTAA AAGGAAAGAT TTTGCCAATA TGACCAGCTT GGTGGACCTG 
ACTCTATCCA GGAATACAAT AAGTTTTATT ACACCTCATG CTTTCGCTGA CCTACGAAAT 
TTGAGGGCTT TGCATTTGAA TAGCAACAGA TTGACTAAAA TTACAAATGA TATGTTCAGT 
GGTCTTTCCA ATCTTCATCA TTTGATACTG AACAACAATC AGCTGACTTT AATTTCCTCT 
ACAGCGTTTG ATGATGTCTT CGCCCTTGAG GAGCTGGATC TGTCCTATAA TAATCTAGAA 
ACCATTCCTT GGGATGCTGT TGAGAAGATG GTTAGCTTGC ATACCCTTAG TTTGGATCAC 
AATATGATTG ATAACATTCC TAAGGGGACC TTCTCCCATT TGCACAAGAT GACTCGGTTA 
GATGTGACAT CAAATAAATT GCAGAAGCTA CCACCTGACC CTCTCTTTCA GCGAGCTCAG 
GTACTAGCAA CCTCAGGAAT CATAAGCCCA TCTACTTTTG CATTAAGTTT TGGTGGAAAC 
CCCTTGCATT GCAATTGTGA ATTGTTGTGG TTGAGGCGTC TGTCCAGAGA AGATGACTTA 
GAGACCTGTG CTTCTCCTCC ACTTTTAACT GGCCGCTACT TTTGGTCAAT TCCTGAAGAA 
GAGTTTTTGT GTGAGCCTCC TCTCATTACT CGTCATACAC ATGAGATGAG AGTCCTGGAG 
GGACAAAGGG CAACACTGAG GTGCAAAGCC AGGGGAGACC CTGAGCCTGC AATTCACTGG 
ATTTCTCCTG AAGGGAAGCT TATTTCAAAT GCAACAAGAT CTCTGGTGTA TGATAACGGA 
ACACTTGACA TTCTTATCAC AACTGTAAAG GATACAGGTG CTTTTACCTG CATTGCTTCC 
AATCCTGCTG GGGAAGCAAC ACAAATAGTG GATCTTCATA TAATTAAGCT CCCTCACTTA 
CTAAATAGTA CAAACCATAT CCATGAGCCT GATCCTGGTT CTTCAGATAT CTCAACTTCT 
ACCAAGTCAG GTTCTAATAC AAGCAGTAGT AATGGTGATA CTAAATTGAG TCAAGATAAA 
ATTGTGGTGG CAGAAGCTAC ATCATCAACG GCACTACTTA AATTTAATTT TCAAAGAAAT 
ATCCCTGGAA TACGTATGTT TCAAATCCAG TACAATGGTA CTTATGATGA CACCCTTGTT 
TACAGAATGA TACCTCCTAC GAGCAAAACT TTTCTGGTCA ATAATCTGGC TGCTGGAACT 
ATGTATGACT TGTGTGTCTT GGCCATATAT GATGATGGCA TCACTTCCCT CACTGCCACA 
AGAGTCGTGG GTTGCATCCA GTTTACTACG GAACAGGATT ATGTGCGTTG CCATTTCATG 
CAGTCTCAGT TTTTGGGAGG CACCATGATT ATTATTATTG GTGGAATCAT TGTAGCATCT 
GTGCTGGTAT TCATCATTAT TCTGATGATC CGGTATAAGG TTTGCAACAA TAATGGGCAA 
CACAAGGTCA CCAAGGTTAG CAATGTTTAT TCCCAAACTA ACGGGGCTCA AATACAAGGC 
TGTAGTGTAA CGCTGCCCCA GTCCGTGTCC AAACAAGCTG TGGGACACGA AGAGAATGCC 
CAGTGTTGTA AAGCTACCAG TGACAATGTG ATTCAATCTT CAGAAACTTG TTCGAGTCAG 
GACTCCTCTA CCACTACCTC TGCTTTGCCT CCTTCCTGGA CTTCAAGCAC TTCTGTGTCC 
CAAAAGCAGA AAAGAAAGAC TGGCACAAAG CCAAGTACAG AACCACAGAA TGAAGCCGTC 
ACAAATGTTG AATCCCAAAA CACTAACAGG AACAACTCAA CTGCCTTGCA GTTAGCTAGC 
CGTCCTCCCG ATTCTGTCAC AGAGGGGCCC ACGTCTAAAA GAGCACATAT AAAGCCAAAT 
GCTTTGCTGA CTAATGTTGA CCAGATTGTC CAGGAAACAC AGAGGCTGGA GTTAATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016876537.1
CDS	4015..6174
Translation	MEKILFYLFLIGIAVKAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLATSGIISPSTFALSFGGNPLHCNCELLWLRRLSREDDLETCASPPLLTGRYFWSIPEEEFLCEPPLITRHTHEMRVLEGQRATLRCKARGDPEPAIHWISPEGKLISNATRSLVYDNGTLDILITTVKDTGAFTCIASNPAGEATQIVDLHIIKLPHLLNSTNHIHEPDPGSSDISTSTKSGSNTSSSNGDTKLSQDKIVVAEATSSTALLKFNFQRNIPGIRMFQIQYNGTYDDTLVYRMIPPTSKTFLVNNLAAGTMYDLCVLAIYDDGITSLTATRVVGCIQFTTEQDYVRCHFMQSQFLGGTMIIIIGGIIVASVLVFIIILMIRYKVCNNNGQHKVTKVSNVYSQTNGAQIQGCSVTLPQSVSKQAVGHEENAQCCKATSDNVIQSSETCSSQDSSTTTSALPPSWTSSTSVSQKQKRKTGTKPSTEPQNEAVTNVESQNTNRNNSTALQLASRPPDSVTEGPTSKRAHIKPNALLTNVDQIVQETQRLELI

Target ORF information:

RefSeq Version	XM_017021048.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat and fibronectin type III domain containing 5 (LRFN5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017021048.1

ORF Insert Sequence:

ATGGAAAAAA TTCTTTTTTA TCTGTTTCTC ATTGGCATAG CAGTGAAAGC TCAGATCTGT 
CCAAAGCGTT GTGTCTGTCA GATTTTGTCT CCTAATCTTG CAACCCTTTG TGCCAAGAAA 
GGGCTTTTAT TTGTTCCACC AAACATTGAC AGAAGAACTG TGGAACTGCG GTTGGCAGAC 
AATTTTGTTA CAAATATTAA AAGGAAAGAT TTTGCCAATA TGACCAGCTT GGTGGACCTG 
ACTCTATCCA GGAATACAAT AAGTTTTATT ACACCTCATG CTTTCGCTGA CCTACGAAAT 
TTGAGGGCTT TGCATTTGAA TAGCAACAGA TTGACTAAAA TTACAAATGA TATGTTCAGT 
GGTCTTTCCA ATCTTCATCA TTTGATACTG AACAACAATC AGCTGACTTT AATTTCCTCT 
ACAGCGTTTG ATGATGTCTT CGCCCTTGAG GAGCTGGATC TGTCCTATAA TAATCTAGAA 
ACCATTCCTT GGGATGCTGT TGAGAAGATG GTTAGCTTGC ATACCCTTAG TTTGGATCAC 
AATATGATTG ATAACATTCC TAAGGGGACC TTCTCCCATT TGCACAAGAT GACTCGGTTA 
GATGTGACAT CAAATAAATT GCAGAAGCTA CCACCTGACC CTCTCTTTCA GCGAGCTCAG 
GTACTAGCAA CCTCAGGAAT CATAAGCCCA TCTACTTTTG CATTAAGTTT TGGTGGAAAC 
CCCTTGCATT GCAATTGTGA ATTGTTGTGG TTGAGGCGTC TGTCCAGAGA AGATGACTTA 
GAGACCTGTG CTTCTCCTCC ACTTTTAACT GGCCGCTACT TTTGGTCAAT TCCTGAAGAA 
GAGTTTTTGT GTGAGCCTCC TCTCATTACT CGTCATACAC ATGAGATGAG AGTCCTGGAG 
GGACAAAGGG CAACACTGAG GTGCAAAGCC AGGGGAGACC CTGAGCCTGC AATTCACTGG 
ATTTCTCCTG AAGGGAAGCT TATTTCAAAT GCAACAAGAT CTCTGGTGTA TGATAACGGA 
ACACTTGACA TTCTTATCAC AACTGTAAAG GATACAGGTG CTTTTACCTG CATTGCTTCC 
AATCCTGCTG GGGAAGCAAC ACAAATAGTG GATCTTCATA TAATTAAGCT CCCTCACTTA 
CTAAATAGTA CAAACCATAT CCATGAGCCT GATCCTGGTT CTTCAGATAT CTCAACTTCT 
ACCAAGTCAG GTTCTAATAC AAGCAGTAGT AATGGTGATA CTAAATTGAG TCAAGATAAA 
ATTGTGGTGG CAGAAGCTAC ATCATCAACG GCACTACTTA AATTTAATTT TCAAAGAAAT 
ATCCCTGGAA TACGTATGTT TCAAATCCAG TACAATGGTA CTTATGATGA CACCCTTGTT 
TACAGAATGA TACCTCCTAC GAGCAAAACT TTTCTGGTCA ATAATCTGGC TGCTGGAACT 
ATGTATGACT TGTGTGTCTT GGCCATATAT GATGATGGCA TCACTTCCCT CACTGCCACA 
AGAGTCGTGG GTTGCATCCA GTTTACTACG GAACAGGATT ATGTGCGTTG CCATTTCATG 
CAGTCTCAGT TTTTGGGAGG CACCATGATT ATTATTATTG GTGGAATCAT TGTAGCATCT 
GTGCTGGTAT TCATCATTAT TCTGATGATC CGGTATAAGG TTTGCAACAA TAATGGGCAA 
CACAAGGTCA CCAAGGTTAG CAATGTTTAT TCCCAAACTA ACGGGGCTCA AATACAAGGC 
TGTAGTGTAA CGCTGCCCCA GTCCGTGTCC AAACAAGCTG TGGGACACGA AGAGAATGCC 
CAGTGTTGTA AAGCTACCAG TGACAATGTG ATTCAATCTT CAGAAACTTG TTCGAGTCAG 
GACTCCTCTA CCACTACCTC TGCTTTGCCT CCTTCCTGGA CTTCAAGCAC TTCTGTGTCC 
CAAAAGCAGA AAAGAAAGAC TGGCACAAAG CCAAGTACAG AACCACAGAA TGAAGCCGTC 
ACAAATGTTG AATCCCAAAA CACTAACAGG AACAACTCAA CTGCCTTGCA GTTAGCTAGC 
CGTCCTCCCG ATTCTGTCAC AGAGGGGCCC ACGTCTAAAA GAGCACATAT AAAGCCAAAT 
GCTTTGCTGA CTAATGTTGA CCAGATTGTC CAGGAAACAC AGAGGCTGGA GTTAATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structural basis of trans-synaptic interactions between PTP? and SALMs for inducing synapse formation.
Nature communications9(1)269(2018 Jan)
Goto-Ito S,Yamagata A,Sato Y,Uemura T,Shiroshima T,Maeda A,Imai A,Mori H,Yoshida T,Fukai S

Structural basis of SALM5-induced PTP? dimerization for synaptic differentiation.
Nature communications9(1)268(2018 Jan)
Lin Z,Liu J,Ding H,Xu F,Liu H

Neuron-specific SALM5 limits inflammation in the CNS via its interaction with HVEM.
Science advances2(4)e1500637(2016 Apr)
Zhu Y,Yao S,Augustine MM,Xu H,Wang J,Sun J,Broadwater M,Ruff W,Luo L,Zhu G,Tamada K,Chen L

Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval.
The pharmacogenomics journal14(1)6-13(2014 Feb)
Avery CL,Sitlani CM,Arking DE,Arnett DK,Bis JC,Boerwinkle E,Buckley BM,Ida Chen YD,de Craen AJ,Eijgelsheim M,Enquobahrie D,Evans DS,Ford I,Garcia ME,Gudnason V,Harris TB,Heckbert SR,Hochner H,Hofman A,Hsueh WC,Isaacs A,Jukema JW,Knekt P,Kors JA,Krijthe BP,Kristiansson K,Laaksonen M,Liu Y,Li X,Macfarlane PW,Newton-Cheh C,Nieminen MS,Oostra BA,Peloso GM,Porthan K,Rice K,Rivadeneira FF,Rotter JI,Salomaa V,Sattar N,Siscovick DS,Slagboom PE,Smith AV,Sotoodehnia N,Stott DJ,Stricker BH,St?rmer T,Trompet S,Uitterlinden AG,van Duijn C,Westendorp RG,Witteman JC,Whitsel EA,Psaty BM

Genome wide association study for plasma levels of natural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA project.
British journal of haematology157(2)230-9(2012 Apr)
Oudot-Mellakh T,Cohen W,Germain M,Saut N,Kallel C,Zelenika D,Lathrop M,Tr?gou?t DA,Morange PE

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LRFN5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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