CSH2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CSH2
Entrez Gene ID	1443
Full Name	chorionic somatomammotropin hormone 2
Synonyms	CS-2,CSB,GHB1,PL,hCS-B
General protein information	Preferred Names chorionic somatomammotropin hormone 2 Names chorionic somatomammotropin hormone 2 choriomammotropin chorionic somatomammotropin B growth hormone B1 lactogen placental lactogen
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q23.3
Summary	The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity. [provided by RefSeq, Jul 2008].
Disorder MIM:	118820

mRNA and Protein(s)

mRNA	Protein	Name
NM_020991.4	NP_066271.1	chorionic somatomammotropin hormone 2 isoform 1 precursor
NM_022644.3	NP_072170.1	chorionic somatomammotropin hormone 2 isoform 2 precursor
NM_022645.2	NP_072171.1	chorionic somatomammotropin hormone 2 isoform 3 precursor
NM_020991.3	NP_066271.1	chorionic somatomammotropin hormone 2 isoform 1 precursor

Pathways from BioSystems

Homologies

	LOC735307	NP_001036207.1
Pan troglodytes (chimpanzee)	PL-D	NP_001008998.1
Homo sapiens (human)	CSH2	NP_066271.1
	CSH2	NP_001036205.1
Homo sapiens (human)	CSH1	NP_001308.1

Gene Ontology
Bibliography

Related articles in PubMed

Curated eutherian third party data gene data sets.
Premzl M
Data in brief6208-13(2016 Mar)

Third party data gene data set of eutherian growth hormone genes.
Premzl M
Genomics data6166-9(2015 Dec)

Differential placental expression profile of human Growth Hormone/Chorionic Somatomammotropin genes in pregnancies with pre-eclampsia and gestational diabetes mellitus.
M?nnik J, Vaas P, Rull K, Teesalu P, Laan M
Molecular and cellular endocrinology355(1)180-7(2012 May)

Identification of functional CCAAT/enhancer-binding protein and Ets protein binding sites in the human chorionic somatomammotropin enhancer sequences.
Lytras A, Detillieux K, Cattini PA
Journal of molecular endocrinology47(2)179-93(2011 Oct)

Late life metabolic syndrome, early growth, and common polymorphism in the growth hormone and placental lactogen gene cluster.
Day IN, Chen XH, Gaunt TR, King TH, Voropanov A, Ye S, Rodriguez S, Syddall HE, Sayer AA, Dennison EM, Tabassum F, Barker DJ, Cooper C, Phillips DI
The Journal of clinical endocrinology and metabolism89(11)5569-76(2004 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results are consistent with a pleiotropic effect of placental hGH/CSH genes at the maternal-fetal interface relating to the regulation of fetal growth and the risk of affected maternal metabolism.
Title: Differential placental expression profile of human Growth Hormone/Chorionic Somatomammotropin genes in pregnancies with pre-eclampsia and gestational diabetes mellitus.

Data conclude that members of the C/EBP and Ets families can differentially modulate CS-Benh and CS-Aenh activity.
Title: Identification of functional CCAAT/enhancer-binding protein and Ets protein binding sites in the human chorionic somatomammotropin enhancer sequences.

Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Late life metabolic syndrome, early growth, and common polymorphism in the growth hormone and placental lactogen gene cluster.

Cpn10 and placental lactogen are capable of stimulating the synthesis of type I collagen by human osteoblasts in culture
Title: Type I collagen synthesis by human osteoblasts in response to placental lactogen and chaperonin 10, a homolog of early-pregnancy factor.

The following CSH2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CSH2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28989	NM_020991.4 Latest version!	Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
OHu28953	NM_022645.2 Latest version!	Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu28993	NM_022644.3 Latest version!	Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu28989	NM_020991.3	Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CSH2 ( NM_020991.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_066271.1 Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28989
Clone ID Related Accession (Same CDS sequence)	NM_020991.4 , NM_020991.3
Accession Version	NM_020991.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	chorionic somatomammotropin hormone 2 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC015651.18. On Jan 4, 2020 this sequence version replaced NM_020991.3. Transcript Variant: This variant (1) utilizes all five exons, resulting in the longest, most abundant isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL543175.3, V00573.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTGCAG GCTCCCGGAC GTCCCTGCTC CTGGCTTTTG CCCTGCTCTG CCTGCCCTGG 
CTTCAAGAGG CTGGTGCCGT CCAAACCGTT CCGTTATCCA GGCTTTTTGA CCACGCTATG 
CTCCAAGCCC ATCGCGCGCA CCAGCTGGCC ATTGACACCT ACCAGGAGTT TGAAGAAACC 
TATATCCCAA AGGACCAGAA GTATTCATTC CTGCATGACT CCCAGACCTC CTTCTGCTTC 
TCAGACTCTA TTCCGACACC CTCCAACATG GAGGAAACGC AACAGAAATC CAATCTAGAG 
CTGCTCCGCA TCTCCCTGCT GCTCATCGAG TCGTGGCTGG AGCCCGTGCG GTTCCTCAGG 
AGTATGTTCG CCAACAACCT GGTGTATGAC ACCTCGGACA GCGATGACTA TCACCTCCTA 
AAGGACCTAG AGGAAGGCAT CCAAACGCTG ATGGGGAGGC TGGAAGACGG CAGCCGCCGG 
ACTGGGCAGA TCCTCAAGCA GACCTACAGC AAGTTTGACA CAAACTCACA CAACCATGAC 
GCACTGCTCA AGAACTACGG GCTGCTCTAC TGCTTCAGGA AGGACATGGA CAAGGTCGAG 
ACATTCCTGC GCATGGTGCA GTGCCGCTCT GTAGAGGGTA GCTGTGGCTT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066271.1
CDS	64..717
Translation	MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF

Target ORF information:

RefSeq Version	NM_020991.4
Organism	Homo sapiens(human)
Definition	Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020991.4

ORF Insert Sequence:

ATGGCTGCAG GCTCCCGGAC GTCCCTGCTC CTGGCTTTTG CCCTGCTCTG CCTGCCCTGG 
CTTCAAGAGG CTGGTGCCGT CCAAACCGTT CCGTTATCCA GGCTTTTTGA CCACGCTATG 
CTCCAAGCCC ATCGCGCGCA CCAGCTGGCC ATTGACACCT ACCAGGAGTT TGAAGAAACC 
TATATCCCAA AGGACCAGAA GTATTCATTC CTGCATGACT CCCAGACCTC CTTCTGCTTC 
TCAGACTCTA TTCCGACACC CTCCAACATG GAGGAAACGC AACAGAAATC CAATCTAGAG 
CTGCTCCGCA TCTCCCTGCT GCTCATCGAG TCGTGGCTGG AGCCCGTGCG GTTCCTCAGG 
AGTATGTTCG CCAACAACCT GGTGTATGAC ACCTCGGACA GCGATGACTA TCACCTCCTA 
AAGGACCTAG AGGAAGGCAT CCAAACGCTG ATGGGGAGGC TGGAAGACGG CAGCCGCCGG 
ACTGGGCAGA TCCTCAAGCA GACCTACAGC AAGTTTGACA CAAACTCACA CAACCATGAC 
GCACTGCTCA AGAACTACGG GCTGCTCTAC TGCTTCAGGA AGGACATGGA CAAGGTCGAG 
ACATTCCTGC GCATGGTGCA GTGCCGCTCT GTAGAGGGTA GCTGTGGCTT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSH2 ( NM_020991.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_066271.1 Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28989
Clone ID Related Accession (Same CDS sequence)	NM_020991.4 , NM_020991.3
Accession Version	NM_020991.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	chorionic somatomammotropin hormone 2 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from J03071.1. On May 16, 2002 this sequence version replaced NM_020991.2. Transcript Variant: This variant (1) utilizes all five exons, resulting in the longest, most abundant isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX361103.2, ERR279850.90.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTGCAG GCTCCCGGAC GTCCCTGCTC CTGGCTTTTG CCCTGCTCTG CCTGCCCTGG 
CTTCAAGAGG CTGGTGCCGT CCAAACCGTT CCGTTATCCA GGCTTTTTGA CCACGCTATG 
CTCCAAGCCC ATCGCGCGCA CCAGCTGGCC ATTGACACCT ACCAGGAGTT TGAAGAAACC 
TATATCCCAA AGGACCAGAA GTATTCATTC CTGCATGACT CCCAGACCTC CTTCTGCTTC 
TCAGACTCTA TTCCGACACC CTCCAACATG GAGGAAACGC AACAGAAATC CAATCTAGAG 
CTGCTCCGCA TCTCCCTGCT GCTCATCGAG TCGTGGCTGG AGCCCGTGCG GTTCCTCAGG 
AGTATGTTCG CCAACAACCT GGTGTATGAC ACCTCGGACA GCGATGACTA TCACCTCCTA 
AAGGACCTAG AGGAAGGCAT CCAAACGCTG ATGGGGAGGC TGGAAGACGG CAGCCGCCGG 
ACTGGGCAGA TCCTCAAGCA GACCTACAGC AAGTTTGACA CAAACTCACA CAACCATGAC 
GCACTGCTCA AGAACTACGG GCTGCTCTAC TGCTTCAGGA AGGACATGGA CAAGGTCGAG 
ACATTCCTGC GCATGGTGCA GTGCCGCTCT GTAGAGGGTA GCTGTGGCTT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_066271.1
CDS	116..769
Translation	MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF

Target ORF information:

RefSeq Version	NM_020991.3
Organism	Homo sapiens(human)
Definition	Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020991.3

ORF Insert Sequence:

ATGGCTGCAG GCTCCCGGAC GTCCCTGCTC CTGGCTTTTG CCCTGCTCTG CCTGCCCTGG 
CTTCAAGAGG CTGGTGCCGT CCAAACCGTT CCGTTATCCA GGCTTTTTGA CCACGCTATG 
CTCCAAGCCC ATCGCGCGCA CCAGCTGGCC ATTGACACCT ACCAGGAGTT TGAAGAAACC 
TATATCCCAA AGGACCAGAA GTATTCATTC CTGCATGACT CCCAGACCTC CTTCTGCTTC 
TCAGACTCTA TTCCGACACC CTCCAACATG GAGGAAACGC AACAGAAATC CAATCTAGAG 
CTGCTCCGCA TCTCCCTGCT GCTCATCGAG TCGTGGCTGG AGCCCGTGCG GTTCCTCAGG 
AGTATGTTCG CCAACAACCT GGTGTATGAC ACCTCGGACA GCGATGACTA TCACCTCCTA 
AAGGACCTAG AGGAAGGCAT CCAAACGCTG ATGGGGAGGC TGGAAGACGG CAGCCGCCGG 
ACTGGGCAGA TCCTCAAGCA GACCTACAGC AAGTTTGACA CAAACTCACA CAACCATGAC 
GCACTGCTCA AGAACTACGG GCTGCTCTAC TGCTTCAGGA AGGACATGGA CAAGGTCGAG 
ACATTCCTGC GCATGGTGCA GTGCCGCTCT GTAGAGGGTA GCTGTGGCTT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSH2 ( NM_022645.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_072171.1 Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu28953
Clone ID Related Accession (Same CDS sequence)	NM_022645.2
Accession Version	NM_022645.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 369bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-22
Organism	Homo sapiens(human)
Product	chorionic somatomammotropin hormone 2 isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from J03071.1. On May 16, 2002 this sequence version replaced NM_022645.1. Transcript Variant: This variant (3) lacks exons 3 and 4, and encodes an isoform (3) that has an internal deletion relative to isoform 1, but retains the signal sequence, unlike the other exon skipping isoform (4). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2153307, SAMEA2162568 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCTGCAG GCTCCCGGAC GTCCCTGCTC CTGGCTTTTG CCCTGCTCTG CCTGCCCTGG 
CTTCAAGAGG CTGGTGCCGT CCAAACCGTT CCGTTATCCA GGCTTTTTGA CCACGCTATG 
CTCCAAGCCC ATCGCGCGCA CCAGCTGGCC ATTGACACCT ACCAGGAGTT TAGGCTGGAA 
GACGGCAGCC GCCGGACTGG GCAGATCCTC AAGCAGACCT ACAGCAAGTT TGACACAAAC 
TCACACAACC ATGACGCACT GCTCAAGAAC TACGGGCTGC TCTACTGCTT CAGGAAGGAC 
ATGGACAAGG TCGAGACATT CCTGCGCATG GTGCAGTGCC GCTCTGTAGA GGGTAGCTGT 
GGCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_072171.1
CDS	116..484
Translation	MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF

Target ORF information:

RefSeq Version	NM_022645.2
Organism	Homo sapiens(human)
Definition	Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022645.2

ORF Insert Sequence:

ATGGCTGCAG GCTCCCGGAC GTCCCTGCTC CTGGCTTTTG CCCTGCTCTG CCTGCCCTGG 
CTTCAAGAGG CTGGTGCCGT CCAAACCGTT CCGTTATCCA GGCTTTTTGA CCACGCTATG 
CTCCAAGCCC ATCGCGCGCA CCAGCTGGCC ATTGACACCT ACCAGGAGTT TAGGCTGGAA 
GACGGCAGCC GCCGGACTGG GCAGATCCTC AAGCAGACCT ACAGCAAGTT TGACACAAAC 
TCACACAACC ATGACGCACT GCTCAAGAAC TACGGGCTGC TCTACTGCTT CAGGAAGGAC 
ATGGACAAGG TCGAGACATT CCTGCGCATG GTGCAGTGCC GCTCTGTAGA GGGTAGCTGT 
GGCTTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSH2 ( NM_022644.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_072170.1 Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu28993
Clone ID Related Accession (Same CDS sequence)	NM_022644.3
Accession Version	NM_022644.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	chorionic somatomammotropin hormone 2 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EU421716.1. On Jan 24, 2009 this sequence version replaced NM_022644.2. Transcript Variant: This variant (2) contains intron D and encodes an isoform (2) that diverges from all other CS isoforms in the carboxy-terminus due to a frameshift. Early truncation occurs relative to a similarly spliced variant of chorionic somatomammotropin hormone 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX340035.2, BX381935.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGCTGCAG GCTCCCGGAC GTCCCTGCTC CTGGCTTTTG CCCTGCTCTG CCTGCCCTGG 
CTTCAAGAGG CTGGTGCCGT CCAAACCGTT CCGTTATCCA GGCTTTTTGA CCACGCTATG 
CTCCAAGCCC ATCGCGCGCA CCAGCTGGCC ATTGACACCT ACCAGGAGTT TGAAGAAACC 
TATATCCCAA AGGACCAGAA GTATTCATTC CTGCATGACT CCCAGACCTC CTTCTGCTTC 
TCAGACTCTA TTCCGACACC CTCCAACATG GAGGAAACGC AACAGAAATC CAATCTAGAG 
CTGCTCCGCA TCTCCCTGCT GCTCATCGAG TCGTGGCTGG AGCCCGTGCG GTTCCTCAGG 
AGTATGTTCG CCAACAACCT GGTGTATGAC ACCTCGGACA GCGATGACTA TCACCTCCTA 
AAGGACCTAG AGGAAGGCAT CCAAACGCTG ATGGGGGTGA GGGTGGCGCC AGGGGTCGCC 
AATCCTGGAA CCCCACTGGC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_072170.1
CDS	116..619
Translation	MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGVRVAPGVANPGTPLA

Target ORF information:

RefSeq Version	NM_022644.3
Organism	Homo sapiens(human)
Definition	Homo sapiens chorionic somatomammotropin hormone 2 (CSH2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022644.3

ORF Insert Sequence:

ATGGCTGCAG GCTCCCGGAC GTCCCTGCTC CTGGCTTTTG CCCTGCTCTG CCTGCCCTGG 
CTTCAAGAGG CTGGTGCCGT CCAAACCGTT CCGTTATCCA GGCTTTTTGA CCACGCTATG 
CTCCAAGCCC ATCGCGCGCA CCAGCTGGCC ATTGACACCT ACCAGGAGTT TGAAGAAACC 
TATATCCCAA AGGACCAGAA GTATTCATTC CTGCATGACT CCCAGACCTC CTTCTGCTTC 
TCAGACTCTA TTCCGACACC CTCCAACATG GAGGAAACGC AACAGAAATC CAATCTAGAG 
CTGCTCCGCA TCTCCCTGCT GCTCATCGAG TCGTGGCTGG AGCCCGTGCG GTTCCTCAGG 
AGTATGTTCG CCAACAACCT GGTGTATGAC ACCTCGGACA GCGATGACTA TCACCTCCTA 
AAGGACCTAG AGGAAGGCAT CCAAACGCTG ATGGGGGTGA GGGTGGCGCC AGGGGTCGCC 
AATCCTGGAA CCCCACTGGC TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Curated eutherian third party data gene data sets.
Data in brief6208-13(2016 Mar)
Premzl M

Third party data gene data set of eutherian growth hormone genes.
Genomics data6166-9(2015 Dec)
Premzl M

Differential placental expression profile of human Growth Hormone/Chorionic Somatomammotropin genes in pregnancies with pre-eclampsia and gestational diabetes mellitus.
Molecular and cellular endocrinology355(1)180-7(2012 May)
M?nnik J,Vaas P,Rull K,Teesalu P,Laan M

Identification of functional CCAAT/enhancer-binding protein and Ets protein binding sites in the human chorionic somatomammotropin enhancer sequences.
Journal of molecular endocrinology47(2)179-93(2011 Oct)
Lytras A,Detillieux K,Cattini PA

Late life metabolic syndrome, early growth, and common polymorphism in the growth hormone and placental lactogen gene cluster.
The Journal of clinical endocrinology and metabolism89(11)5569-76(2004 Nov)
Day IN,Chen XH,Gaunt TR,King TH,Voropanov A,Ye S,Rodriguez S,Syddall HE,Sayer AA,Dennison EM,Tabassum F,Barker DJ,Cooper C,Phillips DI

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CSH2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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