GATA5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GATA5
Entrez Gene ID	140628
Full Name	GATA binding protein 5
Synonyms	GATAS,bB379O24.1
General protein information	Preferred Names GATA binding protein 5 Names transcription factor GATA-5 GATA binding factor-5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.33
Summary	The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. [provided by RefSeq, Jul 2008].
Disorder MIM:	611496

mRNA and Protein(s)

mRNA	Protein	Name
XM_006723699.3	XP_006723762.1	transcription factor GATA-5 isoform X1
XM_006723699.2	XP_006723762.1	transcription factor GATA-5 isoform X1
NM_080473.5	NP_536721.1	transcription factor GATA-5
NM_080473.4	NP_536721.1	transcription factor GATA-5

Pathways from BioSystems

Homologies

Bos taurus (cattle)	GATA5	NP_001029393.1
Pan troglodytes (chimpanzee)	GATA5	XP_514767.3
	LOC720048	XP_001115055.2
Mus musculus (house mouse)	Gata5	NP_032119.2
Xenopus tropicalis (tropical clawed frog)	gata5	NP_001011384.1
Homo sapiens (human)	GATA5	NP_536721.1
Danio rerio (zebrafish)	gata5	NP_571310.2
Gallus gallus (chicken)	GATA5	NP_990752.1
Canis lupus familiaris (dog)	GATA5	XP_543086.2
Rattus norvegicus (Norway rat)	Gata5	NP_001019487.1

Gene Ontology
Bibliography

Related articles in PubMed

Compound heterozygous GATA5 mutations in a girl with hydrops fetalis, congenital heart defects and genital anomalies.
Hempel M, Casar Tena T, Diehl T, Burczyk MS, Strom TM, Kubisch C, Philipp M, Lessel D
Human genetics136(3)339-346(2017 Mar)

WT1, MSH6, GATA5 and PAX5 as epigenetic oral squamous cell carcinoma biomarkers - a short report.
Ribeiro IP, Caramelo F, Marques F, Domingues A, Mesquita M, Barroso L, Prazeres H, Juli?o MJ, Baptista IP, Ferreira A, Melo JB, Carreira IM
Cellular oncology (Dordrecht)39(6)573-582(2016 Dec)

Anisomycin-induced GATA-6 degradation accompanying a decrease of proliferation of colorectal cancer cell.
Ushijima H, Horyozaki A, Maeda M
Biochemical and biophysical research communications478(1)481-485(2016 09)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

findings show that GATA5 mutations, in addition to heart diseases, can result in congenital abnormalities of the female genitourinary tract in humans
Title: Compound heterozygous GATA5 mutations in a girl with hydrops fetalis, congenital heart defects and genital anomalies.

The Correlation between GATA5, WT1 and PAX5 methylation and clinical/histological parameters is suggestive of applicability of these markers in non-invasive (epi)genetic testing in hepatocellular carcinoma (HCC).
Title: Aberrant methylation of tumour suppressor genes WT1, GATA5 and PAX5 in hepatocellular carcinoma.

we identified gene promoter methylation signatures (WT1, MSH6, GATA5 and PAX5) that are strongly correlated to, and can have a predictive value for the clinical outcome of oral squamous cell carcinoma patients
Title: WT1, MSH6, GATA5 and PAX5 as epigenetic oral squamous cell carcinoma biomarkers - a short report.

These results suggest that the induction of GATA-6 dysfunction may be more effective for chemotherapy for colorectal cancer, although the mechanism underlying the synergistic effect of 5-FU and anisomycin remains unknown.
Title: Anisomycin-induced GATA-6 degradation accompanying a decrease of proliferation of colorectal cancer cell.

A multivariate regression model revealed that the effects of both the promoter methylation and the exonic SNPs in GATA5 were independent.This interaction between GATA5 variants and GATA5 promoter methylation indicates that the association of either factor with gastric disease progression is modified by the other
Title: Epigenetic and genetic variation in GATA5 is associated with gastric disease risk.

The following GATA5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GATA5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05761	NM_080473.5 Latest version!	Homo sapiens GATA binding protein 5 (GATA5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu05761	XM_006723699.3 Latest version!	Homo sapiens GATA binding protein 5 (GATA5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu05761	XM_006723699.2	Homo sapiens GATA binding protein 5 (GATA5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu05761	NM_080473.4	Homo sapiens GATA binding protein 5 (GATA5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GATA5 ( NM_080473.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_536721.1 Homo sapiens GATA binding protein 5 (GATA5), mRNA.

Price & Availability↑

CloneID	OHu05761
Clone ID Related Accession (Same CDS sequence)	XM_006723699.3 , XM_006723699.2 , NM_080473.5 , NM_080473.4
Accession Version	NM_080473.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	transcription factor GATA-5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL499627.23. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_080473.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC047790.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000252997.3/ ENSP00000252997.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTACCAGA GCCTGGCGCT GGCCGCGAGC CCCCGCCAGG CCGCCTACGC CGACTCGGGC 
TCCTTCCTGC ACGCTCCGGG CGCCGGCTCT CCGATGTTTG TGCCGCCGGC GCGCGTCCCC 
TCGATGCTGT CCTACCTGTC CGGGTGTGAG CCGAGCCCGC AGCCCCCCGA GCTCGCTGCG 
CGCCCCGGCT GGGCGCAGAC AGCCACCGCG GATTCGTCGG CCTTCGGCCC GGGCAGTCCG 
CACCCCCCAG CCGCGCACCC GCCCGGGGCC ACCGCCTTCC CTTTCGCGCA CAGCCCCTCG 
GGGCCCGGCA GCGGCGGCAG CGCGGGGGGC CGAGACGGCA GTGCCTACCA GGGCGCGCTG 
TTGCCTCGAG AACAGTTCGC GGCCCCGCTT GGGCGGCCGG TGGGGACCTC GTACTCCGCC 
ACCTACCCGG CCTACGTGAG CCCCGACGTG GCCCAGTCCT GGACTGCCGG GCCCTTCGAT 
GGCAGCGTCC TGCACGGCCT CCCAGGCCGC AGGCCCACCT TCGTGTCCGA CTTCTTGGAG 
GAGTTCCCGG GTGAGGGTCG TGAGTGTGTC AACTGCGGGG CCCTGTCCAC ACCGCTGTGG 
CGCCGAGACG GCACCGGCCA CTACCTGTGC AATGCCTGCG GCCTCTACCA CAAGATGAAT 
GGCGTCAACC GGCCGCTCGT TCGGCCTCAG AAGCGCCTGT CCTCGTCCCG CCGCGCCGGC 
CTCTGCTGCA CCAACTGCCA CACGACCAAC ACCACGCTGT GGCGGCGGAA CTCGGAGGGG 
GAGCCCGTGT GCAATGCCTG CGGCCTCTAC ATGAAGCTGC ACGGGGTGCC GCGGCCTCTG 
GCTATGAAGA AGGAAAGCAT CCAGACACGG AAGCGGAAGC CAAAGACCAT CGCCAAGGCC 
AGGGGCTCCT CAGGATCCAC AAGGAATGCC TCGGCCTCCC CATCTGCTGT CGCCAGCACT 
GACAGCTCAG CAGCCACTTC GAAAGCCAAG CCCAGCCTGG CGTCCCCAGT GTGCCCTGGG 
CCCAGCATGG CCCCCCAGGC CTCTGGCCAG GAGGATGACT CTCTTGCCCC CGGCCACTTG 
GAGTTCAAGT TCGAGCCTGA GGACTTTGCC TTCCCCTCCA CGGCCCCAAG CCCCCAGGCT 
GGCCTCAGGG GGGCTCTGCG CCAAGAGGCC TGGTGTGCGC TGGCCTTGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_536721.1
CDS	88..1281
Translation	MYQSLALAASPRQAAYADSGSFLHAPGAGSPMFVPPARVPSMLSYLSGCEPSPQPPELAARPGWAQTATADSSAFGPGSPHPPAAHPPGATAFPFAHSPSGPGSGGSAGGRDGSAYQGALLPREQFAAPLGRPVGTSYSATYPAYVSPDVAQSWTAGPFDGSVLHGLPGRRPTFVSDFLEEFPGEGRECVNCGALSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRAGLCCTNCHTTNTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKTIAKARGSSGSTRNASASPSAVASTDSSAATSKAKPSLASPVCPGPSMAPQASGQEDDSLAPGHLEFKFEPEDFAFPSTAPSPQAGLRGALRQEAWCALALA

Target ORF information:

RefSeq Version	NM_080473.5
Organism	Homo sapiens(human)
Definition	Homo sapiens GATA binding protein 5 (GATA5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080473.5

ORF Insert Sequence:

ATGTACCAGA GCCTGGCGCT GGCCGCGAGC CCCCGCCAGG CCGCCTACGC CGACTCGGGC 
TCCTTCCTGC ACGCTCCGGG CGCCGGCTCT CCGATGTTTG TGCCGCCGGC GCGCGTCCCC 
TCGATGCTGT CCTACCTGTC CGGGTGTGAG CCGAGCCCGC AGCCCCCCGA GCTCGCTGCG 
CGCCCCGGCT GGGCGCAGAC AGCCACCGCG GATTCGTCGG CCTTCGGCCC GGGCAGTCCG 
CACCCCCCAG CCGCGCACCC GCCCGGGGCC ACCGCCTTCC CTTTCGCGCA CAGCCCCTCG 
GGGCCCGGCA GCGGCGGCAG CGCGGGGGGC CGAGACGGCA GTGCCTACCA GGGCGCGCTG 
TTGCCTCGAG AACAGTTCGC GGCCCCGCTT GGGCGGCCGG TGGGGACCTC GTACTCCGCC 
ACCTACCCGG CCTACGTGAG CCCCGACGTG GCCCAGTCCT GGACTGCCGG GCCCTTCGAT 
GGCAGCGTCC TGCACGGCCT CCCAGGCCGC AGGCCCACCT TCGTGTCCGA CTTCTTGGAG 
GAGTTCCCGG GTGAGGGTCG TGAGTGTGTC AACTGCGGGG CCCTGTCCAC ACCGCTGTGG 
CGCCGAGACG GCACCGGCCA CTACCTGTGC AATGCCTGCG GCCTCTACCA CAAGATGAAT 
GGCGTCAACC GGCCGCTCGT TCGGCCTCAG AAGCGCCTGT CCTCGTCCCG CCGCGCCGGC 
CTCTGCTGCA CCAACTGCCA CACGACCAAC ACCACGCTGT GGCGGCGGAA CTCGGAGGGG 
GAGCCCGTGT GCAATGCCTG CGGCCTCTAC ATGAAGCTGC ACGGGGTGCC GCGGCCTCTG 
GCTATGAAGA AGGAAAGCAT CCAGACACGG AAGCGGAAGC CAAAGACCAT CGCCAAGGCC 
AGGGGCTCCT CAGGATCCAC AAGGAATGCC TCGGCCTCCC CATCTGCTGT CGCCAGCACT 
GACAGCTCAG CAGCCACTTC GAAAGCCAAG CCCAGCCTGG CGTCCCCAGT GTGCCCTGGG 
CCCAGCATGG CCCCCCAGGC CTCTGGCCAG GAGGATGACT CTCTTGCCCC CGGCCACTTG 
GAGTTCAAGT TCGAGCCTGA GGACTTTGCC TTCCCCTCCA CGGCCCCAAG CCCCCAGGCT 
GGCCTCAGGG GGGCTCTGCG CCAAGAGGCC TGGTGTGCGC TGGCCTTGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GATA5 ( NM_080473.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_536721.1 Homo sapiens GATA binding protein 5 (GATA5), mRNA.

Price & Availability↑

CloneID	OHu05761
Clone ID Related Accession (Same CDS sequence)	XM_006723699.3 , XM_006723699.2 , NM_080473.5 , NM_080473.4
Accession Version	NM_080473.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	transcription factor GATA-5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL499627.23. This sequence is a reference standard in the RefSeqGene project. On Oct 7, 2007 this sequence version replaced NM_080473.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC047790.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTACCAGA GCCTGGCGCT GGCCGCGAGC CCCCGCCAGG CCGCCTACGC CGACTCGGGC 
TCCTTCCTGC ACGCTCCGGG CGCCGGCTCT CCGATGTTTG TGCCGCCGGC GCGCGTCCCC 
TCGATGCTGT CCTACCTGTC CGGGTGTGAG CCGAGCCCGC AGCCCCCCGA GCTCGCTGCG 
CGCCCCGGCT GGGCGCAGAC AGCCACCGCG GATTCGTCGG CCTTCGGCCC GGGCAGTCCG 
CACCCCCCAG CCGCGCACCC GCCCGGGGCC ACCGCCTTCC CTTTCGCGCA CAGCCCCTCG 
GGGCCCGGCA GCGGCGGCAG CGCGGGGGGC CGAGACGGCA GTGCCTACCA GGGCGCGCTG 
TTGCCTCGAG AACAGTTCGC GGCCCCGCTT GGGCGGCCGG TGGGGACCTC GTACTCCGCC 
ACCTACCCGG CCTACGTGAG CCCCGACGTG GCCCAGTCCT GGACTGCCGG GCCCTTCGAT 
GGCAGCGTCC TGCACGGCCT CCCAGGCCGC AGGCCCACCT TCGTGTCCGA CTTCTTGGAG 
GAGTTCCCGG GTGAGGGTCG TGAGTGTGTC AACTGCGGGG CCCTGTCCAC ACCGCTGTGG 
CGCCGAGACG GCACCGGCCA CTACCTGTGC AATGCCTGCG GCCTCTACCA CAAGATGAAT 
GGCGTCAACC GGCCGCTCGT TCGGCCTCAG AAGCGCCTGT CCTCGTCCCG CCGCGCCGGC 
CTCTGCTGCA CCAACTGCCA CACGACCAAC ACCACGCTGT GGCGGCGGAA CTCGGAGGGG 
GAGCCCGTGT GCAATGCCTG CGGCCTCTAC ATGAAGCTGC ACGGGGTGCC GCGGCCTCTG 
GCTATGAAGA AGGAAAGCAT CCAGACACGG AAGCGGAAGC CAAAGACCAT CGCCAAGGCC 
AGGGGCTCCT CAGGATCCAC AAGGAATGCC TCGGCCTCCC CATCTGCTGT CGCCAGCACT 
GACAGCTCAG CAGCCACTTC GAAAGCCAAG CCCAGCCTGG CGTCCCCAGT GTGCCCTGGG 
CCCAGCATGG CCCCCCAGGC CTCTGGCCAG GAGGATGACT CTCTTGCCCC CGGCCACTTG 
GAGTTCAAGT TCGAGCCTGA GGACTTTGCC TTCCCCTCCA CGGCCCCAAG CCCCCAGGCT 
GGCCTCAGGG GGGCTCTGCG CCAAGAGGCC TGGTGTGCGC TGGCCTTGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_536721.1
CDS	63..1256
Translation	MYQSLALAASPRQAAYADSGSFLHAPGAGSPMFVPPARVPSMLSYLSGCEPSPQPPELAARPGWAQTATADSSAFGPGSPHPPAAHPPGATAFPFAHSPSGPGSGGSAGGRDGSAYQGALLPREQFAAPLGRPVGTSYSATYPAYVSPDVAQSWTAGPFDGSVLHGLPGRRPTFVSDFLEEFPGEGRECVNCGALSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRAGLCCTNCHTTNTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKTIAKARGSSGSTRNASASPSAVASTDSSAATSKAKPSLASPVCPGPSMAPQASGQEDDSLAPGHLEFKFEPEDFAFPSTAPSPQAGLRGALRQEAWCALALA

Target ORF information:

RefSeq Version	NM_080473.4
Organism	Homo sapiens(human)
Definition	Homo sapiens GATA binding protein 5 (GATA5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080473.4

ORF Insert Sequence:

ATGTACCAGA GCCTGGCGCT GGCCGCGAGC CCCCGCCAGG CCGCCTACGC CGACTCGGGC 
TCCTTCCTGC ACGCTCCGGG CGCCGGCTCT CCGATGTTTG TGCCGCCGGC GCGCGTCCCC 
TCGATGCTGT CCTACCTGTC CGGGTGTGAG CCGAGCCCGC AGCCCCCCGA GCTCGCTGCG 
CGCCCCGGCT GGGCGCAGAC AGCCACCGCG GATTCGTCGG CCTTCGGCCC GGGCAGTCCG 
CACCCCCCAG CCGCGCACCC GCCCGGGGCC ACCGCCTTCC CTTTCGCGCA CAGCCCCTCG 
GGGCCCGGCA GCGGCGGCAG CGCGGGGGGC CGAGACGGCA GTGCCTACCA GGGCGCGCTG 
TTGCCTCGAG AACAGTTCGC GGCCCCGCTT GGGCGGCCGG TGGGGACCTC GTACTCCGCC 
ACCTACCCGG CCTACGTGAG CCCCGACGTG GCCCAGTCCT GGACTGCCGG GCCCTTCGAT 
GGCAGCGTCC TGCACGGCCT CCCAGGCCGC AGGCCCACCT TCGTGTCCGA CTTCTTGGAG 
GAGTTCCCGG GTGAGGGTCG TGAGTGTGTC AACTGCGGGG CCCTGTCCAC ACCGCTGTGG 
CGCCGAGACG GCACCGGCCA CTACCTGTGC AATGCCTGCG GCCTCTACCA CAAGATGAAT 
GGCGTCAACC GGCCGCTCGT TCGGCCTCAG AAGCGCCTGT CCTCGTCCCG CCGCGCCGGC 
CTCTGCTGCA CCAACTGCCA CACGACCAAC ACCACGCTGT GGCGGCGGAA CTCGGAGGGG 
GAGCCCGTGT GCAATGCCTG CGGCCTCTAC ATGAAGCTGC ACGGGGTGCC GCGGCCTCTG 
GCTATGAAGA AGGAAAGCAT CCAGACACGG AAGCGGAAGC CAAAGACCAT CGCCAAGGCC 
AGGGGCTCCT CAGGATCCAC AAGGAATGCC TCGGCCTCCC CATCTGCTGT CGCCAGCACT 
GACAGCTCAG CAGCCACTTC GAAAGCCAAG CCCAGCCTGG CGTCCCCAGT GTGCCCTGGG 
CCCAGCATGG CCCCCCAGGC CTCTGGCCAG GAGGATGACT CTCTTGCCCC CGGCCACTTG 
GAGTTCAAGT TCGAGCCTGA GGACTTTGCC TTCCCCTCCA CGGCCCCAAG CCCCCAGGCT 
GGCCTCAGGG GGGCTCTGCG CCAAGAGGCC TGGTGTGCGC TGGCCTTGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GATA5 ( XM_006723699.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723762.1 Homo sapiens GATA binding protein 5 (GATA5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu05761
Clone ID Related Accession (Same CDS sequence)	XM_006723699.3 , XM_006723699.2 , NM_080473.5 , NM_080473.4
Accession Version	XM_006723699.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transcription factor GATA-5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006723699.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACCAGA GCCTGGCGCT GGCCGCGAGC CCCCGCCAGG CCGCCTACGC CGACTCGGGC 
TCCTTCCTGC ACGCTCCGGG CGCCGGCTCT CCGATGTTTG TGCCGCCGGC GCGCGTCCCC 
TCGATGCTGT CCTACCTGTC CGGGTGTGAG CCGAGCCCGC AGCCCCCCGA GCTCGCTGCG 
CGCCCCGGCT GGGCGCAGAC AGCCACCGCG GATTCGTCGG CCTTCGGCCC GGGCAGTCCG 
CACCCCCCAG CCGCGCACCC GCCCGGGGCC ACCGCCTTCC CTTTCGCGCA CAGCCCCTCG 
GGGCCCGGCA GCGGCGGCAG CGCGGGGGGC CGAGACGGCA GTGCCTACCA GGGCGCGCTG 
TTGCCTCGAG AACAGTTCGC GGCCCCGCTT GGGCGGCCGG TGGGGACCTC GTACTCCGCC 
ACCTACCCGG CCTACGTGAG CCCCGACGTG GCCCAGTCCT GGACTGCCGG GCCCTTCGAT 
GGCAGCGTCC TGCACGGCCT CCCAGGCCGC AGGCCCACCT TCGTGTCCGA CTTCTTGGAG 
GAGTTCCCGG GTGAGGGTCG TGAGTGTGTC AACTGCGGGG CCCTGTCCAC ACCGCTGTGG 
CGCCGAGACG GCACCGGCCA CTACCTGTGC AATGCCTGCG GCCTCTACCA CAAGATGAAT 
GGCGTCAACC GGCCGCTCGT TCGGCCTCAG AAGCGCCTGT CCTCGTCCCG CCGCGCCGGC 
CTCTGCTGCA CCAACTGCCA CACGACCAAC ACCACGCTGT GGCGGCGGAA CTCGGAGGGG 
GAGCCCGTGT GCAATGCCTG CGGCCTCTAC ATGAAGCTGC ACGGGGTGCC GCGGCCTCTG 
GCTATGAAGA AGGAAAGCAT CCAGACACGG AAGCGGAAGC CAAAGACCAT CGCCAAGGCC 
AGGGGCTCCT CAGGATCCAC AAGGAATGCC TCGGCCTCCC CATCTGCTGT CGCCAGCACT 
GACAGCTCAG CAGCCACTTC GAAAGCCAAG CCCAGCCTGG CGTCCCCAGT GTGCCCTGGG 
CCCAGCATGG CCCCCCAGGC CTCTGGCCAG GAGGATGACT CTCTTGCCCC CGGCCACTTG 
GAGTTCAAGT TCGAGCCTGA GGACTTTGCC TTCCCCTCCA CGGCCCCAAG CCCCCAGGCT 
GGCCTCAGGG GGGCTCTGCG CCAAGAGGCC TGGTGTGCGC TGGCCTTGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006723762.1
CDS	83..1276
Translation	MYQSLALAASPRQAAYADSGSFLHAPGAGSPMFVPPARVPSMLSYLSGCEPSPQPPELAARPGWAQTATADSSAFGPGSPHPPAAHPPGATAFPFAHSPSGPGSGGSAGGRDGSAYQGALLPREQFAAPLGRPVGTSYSATYPAYVSPDVAQSWTAGPFDGSVLHGLPGRRPTFVSDFLEEFPGEGRECVNCGALSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRAGLCCTNCHTTNTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKTIAKARGSSGSTRNASASPSAVASTDSSAATSKAKPSLASPVCPGPSMAPQASGQEDDSLAPGHLEFKFEPEDFAFPSTAPSPQAGLRGALRQEAWCALALA

Target ORF information:

RefSeq Version	XM_006723699.3
Organism	Homo sapiens(human)
Definition	Homo sapiens GATA binding protein 5 (GATA5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006723699.3

ORF Insert Sequence:

ATGTACCAGA GCCTGGCGCT GGCCGCGAGC CCCCGCCAGG CCGCCTACGC CGACTCGGGC 
TCCTTCCTGC ACGCTCCGGG CGCCGGCTCT CCGATGTTTG TGCCGCCGGC GCGCGTCCCC 
TCGATGCTGT CCTACCTGTC CGGGTGTGAG CCGAGCCCGC AGCCCCCCGA GCTCGCTGCG 
CGCCCCGGCT GGGCGCAGAC AGCCACCGCG GATTCGTCGG CCTTCGGCCC GGGCAGTCCG 
CACCCCCCAG CCGCGCACCC GCCCGGGGCC ACCGCCTTCC CTTTCGCGCA CAGCCCCTCG 
GGGCCCGGCA GCGGCGGCAG CGCGGGGGGC CGAGACGGCA GTGCCTACCA GGGCGCGCTG 
TTGCCTCGAG AACAGTTCGC GGCCCCGCTT GGGCGGCCGG TGGGGACCTC GTACTCCGCC 
ACCTACCCGG CCTACGTGAG CCCCGACGTG GCCCAGTCCT GGACTGCCGG GCCCTTCGAT 
GGCAGCGTCC TGCACGGCCT CCCAGGCCGC AGGCCCACCT TCGTGTCCGA CTTCTTGGAG 
GAGTTCCCGG GTGAGGGTCG TGAGTGTGTC AACTGCGGGG CCCTGTCCAC ACCGCTGTGG 
CGCCGAGACG GCACCGGCCA CTACCTGTGC AATGCCTGCG GCCTCTACCA CAAGATGAAT 
GGCGTCAACC GGCCGCTCGT TCGGCCTCAG AAGCGCCTGT CCTCGTCCCG CCGCGCCGGC 
CTCTGCTGCA CCAACTGCCA CACGACCAAC ACCACGCTGT GGCGGCGGAA CTCGGAGGGG 
GAGCCCGTGT GCAATGCCTG CGGCCTCTAC ATGAAGCTGC ACGGGGTGCC GCGGCCTCTG 
GCTATGAAGA AGGAAAGCAT CCAGACACGG AAGCGGAAGC CAAAGACCAT CGCCAAGGCC 
AGGGGCTCCT CAGGATCCAC AAGGAATGCC TCGGCCTCCC CATCTGCTGT CGCCAGCACT 
GACAGCTCAG CAGCCACTTC GAAAGCCAAG CCCAGCCTGG CGTCCCCAGT GTGCCCTGGG 
CCCAGCATGG CCCCCCAGGC CTCTGGCCAG GAGGATGACT CTCTTGCCCC CGGCCACTTG 
GAGTTCAAGT TCGAGCCTGA GGACTTTGCC TTCCCCTCCA CGGCCCCAAG CCCCCAGGCT 
GGCCTCAGGG GGGCTCTGCG CCAAGAGGCC TGGTGTGCGC TGGCCTTGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GATA5 ( XM_006723699.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723762.1 Homo sapiens GATA binding protein 5 (GATA5), transcript variant X1, mRNA.

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CloneID	OHu05761
Clone ID Related Accession (Same CDS sequence)	XM_006723699.3 , XM_006723699.2 , NM_080473.5 , NM_080473.4
Accession Version	XM_006723699.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1194bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	transcription factor GATA-5 isoform X1
Comment

ATGTACCAGA GCCTGGCGCT GGCCGCGAGC CCCCGCCAGG CCGCCTACGC CGACTCGGGC 
TCCTTCCTGC ACGCTCCGGG CGCCGGCTCT CCGATGTTTG TGCCGCCGGC GCGCGTCCCC 
TCGATGCTGT CCTACCTGTC CGGGTGTGAG CCGAGCCCGC AGCCCCCCGA GCTCGCTGCG 
CGCCCCGGCT GGGCGCAGAC AGCCACCGCG GATTCGTCGG CCTTCGGCCC GGGCAGTCCG 
CACCCCCCAG CCGCGCACCC GCCCGGGGCC ACCGCCTTCC CTTTCGCGCA CAGCCCCTCG 
GGGCCCGGCA GCGGCGGCAG CGCGGGGGGC CGAGACGGCA GTGCCTACCA GGGCGCGCTG 
TTGCCTCGAG AACAGTTCGC GGCCCCGCTT GGGCGGCCGG TGGGGACCTC GTACTCCGCC 
ACCTACCCGG CCTACGTGAG CCCCGACGTG GCCCAGTCCT GGACTGCCGG GCCCTTCGAT 
GGCAGCGTCC TGCACGGCCT CCCAGGCCGC AGGCCCACCT TCGTGTCCGA CTTCTTGGAG 
GAGTTCCCGG GTGAGGGTCG TGAGTGTGTC AACTGCGGGG CCCTGTCCAC ACCGCTGTGG 
CGCCGAGACG GCACCGGCCA CTACCTGTGC AATGCCTGCG GCCTCTACCA CAAGATGAAT 
GGCGTCAACC GGCCGCTCGT TCGGCCTCAG AAGCGCCTGT CCTCGTCCCG CCGCGCCGGC 
CTCTGCTGCA CCAACTGCCA CACGACCAAC ACCACGCTGT GGCGGCGGAA CTCGGAGGGG 
GAGCCCGTGT GCAATGCCTG CGGCCTCTAC ATGAAGCTGC ACGGGGTGCC GCGGCCTCTG 
GCTATGAAGA AGGAAAGCAT CCAGACACGG AAGCGGAAGC CAAAGACCAT CGCCAAGGCC 
AGGGGCTCCT CAGGATCCAC AAGGAATGCC TCGGCCTCCC CATCTGCTGT CGCCAGCACT 
GACAGCTCAG CAGCCACTTC GAAAGCCAAG CCCAGCCTGG CGTCCCCAGT GTGCCCTGGG 
CCCAGCATGG CCCCCCAGGC CTCTGGCCAG GAGGATGACT CTCTTGCCCC CGGCCACTTG 
GAGTTCAAGT TCGAGCCTGA GGACTTTGCC TTCCCCTCCA CGGCCCCAAG CCCCCAGGCT 
GGCCTCAGGG GGGCTCTGCG CCAAGAGGCC TGGTGTGCGC TGGCCTTGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006723762.1
Translation	MYQSLALAASPRQAAYADSGSFLHAPGAGSPMFVPPARVPSMLSYLSGCEPSPQPPELAARPGWAQTATADSSAFGPGSPHPPAAHPPGATAFPFAHSPSGPGSGGSAGGRDGSAYQGALLPREQFAAPLGRPVGTSYSATYPAYVSPDVAQSWTAGPFDGSVLHGLPGRRPTFVSDFLEEFPGEGRECVNCGALSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRAGLCCTNCHTTNTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKTIAKARGSSGSTRNASASPSAVASTDSSAATSKAKPSLASPVCPGPSMAPQASGQEDDSLAPGHLEFKFEPEDFAFPSTAPSPQAGLRGALRQEAWCALALA

Target ORF information:

RefSeq Version	XM_006723699.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens GATA binding protein 5 (GATA5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006723699.2

ORF Insert Sequence:

ATGTACCAGA GCCTGGCGCT GGCCGCGAGC CCCCGCCAGG CCGCCTACGC CGACTCGGGC 
TCCTTCCTGC ACGCTCCGGG CGCCGGCTCT CCGATGTTTG TGCCGCCGGC GCGCGTCCCC 
TCGATGCTGT CCTACCTGTC CGGGTGTGAG CCGAGCCCGC AGCCCCCCGA GCTCGCTGCG 
CGCCCCGGCT GGGCGCAGAC AGCCACCGCG GATTCGTCGG CCTTCGGCCC GGGCAGTCCG 
CACCCCCCAG CCGCGCACCC GCCCGGGGCC ACCGCCTTCC CTTTCGCGCA CAGCCCCTCG 
GGGCCCGGCA GCGGCGGCAG CGCGGGGGGC CGAGACGGCA GTGCCTACCA GGGCGCGCTG 
TTGCCTCGAG AACAGTTCGC GGCCCCGCTT GGGCGGCCGG TGGGGACCTC GTACTCCGCC 
ACCTACCCGG CCTACGTGAG CCCCGACGTG GCCCAGTCCT GGACTGCCGG GCCCTTCGAT 
GGCAGCGTCC TGCACGGCCT CCCAGGCCGC AGGCCCACCT TCGTGTCCGA CTTCTTGGAG 
GAGTTCCCGG GTGAGGGTCG TGAGTGTGTC AACTGCGGGG CCCTGTCCAC ACCGCTGTGG 
CGCCGAGACG GCACCGGCCA CTACCTGTGC AATGCCTGCG GCCTCTACCA CAAGATGAAT 
GGCGTCAACC GGCCGCTCGT TCGGCCTCAG AAGCGCCTGT CCTCGTCCCG CCGCGCCGGC 
CTCTGCTGCA CCAACTGCCA CACGACCAAC ACCACGCTGT GGCGGCGGAA CTCGGAGGGG 
GAGCCCGTGT GCAATGCCTG CGGCCTCTAC ATGAAGCTGC ACGGGGTGCC GCGGCCTCTG 
GCTATGAAGA AGGAAAGCAT CCAGACACGG AAGCGGAAGC CAAAGACCAT CGCCAAGGCC 
AGGGGCTCCT CAGGATCCAC AAGGAATGCC TCGGCCTCCC CATCTGCTGT CGCCAGCACT 
GACAGCTCAG CAGCCACTTC GAAAGCCAAG CCCAGCCTGG CGTCCCCAGT GTGCCCTGGG 
CCCAGCATGG CCCCCCAGGC CTCTGGCCAG GAGGATGACT CTCTTGCCCC CGGCCACTTG 
GAGTTCAAGT TCGAGCCTGA GGACTTTGCC TTCCCCTCCA CGGCCCCAAG CCCCCAGGCT 
GGCCTCAGGG GGGCTCTGCG CCAAGAGGCC TGGTGTGCGC TGGCCTTGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Compound heterozygous GATA5 mutations in a girl with hydrops fetalis, congenital heart defects and genital anomalies.
Human genetics136(3)339-346(2017 Mar)
Hempel M,Casar Tena T,Diehl T,Burczyk MS,Strom TM,Kubisch C,Philipp M,Lessel D

WT1, MSH6, GATA5 and PAX5 as epigenetic oral squamous cell carcinoma biomarkers - a short report.
Cellular oncology (Dordrecht)39(6)573-582(2016 Dec)
Ribeiro IP,Caramelo F,Marques F,Domingues A,Mesquita M,Barroso L,Prazeres H,Juli?o MJ,Baptista IP,Ferreira A,Melo JB,Carreira IM

Anisomycin-induced GATA-6 degradation accompanying a decrease of proliferation of colorectal cancer cell.
Biochemical and biophysical research communications478(1)481-485(2016 09)
Ushijima H,Horyozaki A,Maeda M

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GATA5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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