ABRA cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ABRA
Entrez Gene ID	137735
Full Name	actin binding Rho activating protein
Synonyms	STARS
General protein information	Preferred Names actin binding Rho activating protein Names actin-binding Rho-activating protein striated muscle activator of Rho-dependent signaling
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q23.1
Disorder MIM:	609747

mRNA and Protein(s)

mRNA	Protein	Name
NM_139166.5	NP_631905.1	actin-binding Rho-activating protein
XM_024447063.1	XP_024302831.1	actin-binding Rho-activating protein isoform X1
NM_139166.4	NP_631905.1	actin-binding Rho-activating protein

Pathways from BioSystems

Homologies

	ABRA	XP_001088098.1
Danio rerio (zebrafish)	abrab	NP_001003986.1
Canis lupus familiaris (dog)	ABRA	XP_003639492.1
Bos taurus (cattle)	ABRA	NP_001179163.1
Mus musculus (house mouse)	Abra	NP_780665.1
Caenorhabditis elegans (roundworm)	F36F2.1	NP_492426.1
Homo sapiens (human)	ABRA	NP_631905.1
Pan troglodytes (chimpanzee)	ABRA	XP_528210.1
Rattus norvegicus (Norway rat)	Abra	NP_787038.1
Gallus gallus (chicken)	ABRA	XP_428503.3
Xenopus tropicalis (tropical clawed frog)	abra	NP_001106590.1

Gene Ontology
Bibliography

Related articles in PubMed

Striated muscle activator of Rho signalling (STARS) is reduced in ageing human skeletal muscle and targeted by miR-628-5p.
Russell AP, Wallace MA, Kalanon M, Zacharewicz E, Della Gatta PA, Garnham A, Lamon S
Acta physiologica (Oxford, England)220(2)263-274(2017 Jun)

Identification of striated muscle activator of Rho signaling (STARS) as a novel calmodulin target by a newly developed genome-wide screen.
Furuya Y, Denda M, Sakane K, Ogusu T, Takahashi S, Magari M, Kanayama N, Morishita R, Tokumitsu H
Cell calcium60(1)32-40(2016 Jul)

Effect of resistance exercise contraction mode and protein supplementation on members of the STARS signalling pathway.
Vissing K, Rahbek SK, Lamon S, Farup J, Stefanetti RJ, Wallace MA, Vendelbo MH, Russell A
The Journal of physiology591(15)3749-63(2013 Aug)

Genome-wide association scan of dental caries in the permanent dentition.
Wang X, Shaffer JR, Zeng Z, Begum F, Vieira AR, Noel J, Anjomshoaa I, Cuenco KT, Lee MK, Beck J, Boerwinkle E, Cornelis MC, Hu FB, Crosslin DR, Laurie CC, Nelson SC, Doheny KF, Pugh EW, Polk DE, Weyant RJ, Crout R, McNeil DW, Weeks DE, Feingold E, Marazita ML
BMC oral health1257(2012 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest a connection between Ca(2+)-signaling via excitation-contraction coupling and the regulation of STARS-mediated gene expression in muscles.
Title: Identification of striated muscle activator of Rho signaling (STARS) as a novel calmodulin target by a newly developed genome-wide screen.

These results show that resistance exercise provides an acute stimulation of the STARS pathway that is contraction mode dependent.
Title: Effect of resistance exercise contraction mode and protein supplementation on members of the STARS signalling pathway.

STARS signalling pathway is upregulated in response to acute endurance exercise and suggest suggest a novel role co-ordination of PGC-1alpha-induced upregulation of the fat oxidative gene, CPT-1beta.
Title: Striated muscle activator of Rho signalling (STARS) is a PGC-1?/oestrogen-related receptor-? target gene and is upregulated in human skeletal muscle after endurance exercise.

STARS signalling pathway is responsive to changes in skeletal muscle loading and appears to play a role in both human skeletal muscle hypertrophy and atrophy
Title: Regulation of STARS and its downstream targets suggest a novel pathway involved in human skeletal muscle hypertrophy and atrophy.

Modulates the responsiveness of the heart to stress signaling by functioning as a cytoskeletal intermediary between human and transgenic myocyte enhancer factor-2 and serum response factor.
Title: Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity.

The following ABRA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ABRA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09034	NM_139166.5 Latest version!	Homo sapiens actin binding Rho activating protein (ABRA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu09034	XM_024447063.1 Latest version!	Homo sapiens actin binding Rho activating protein (ABRA), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
View Old Accession Versions >>
OHu09034	NM_139166.4	Homo sapiens actin binding Rho activating protein (ABRA), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ABRA ( NM_139166.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_631905.1 Homo sapiens actin binding Rho activating protein (ABRA), mRNA.

Price & Availability↑

CloneID	OHu09034
Clone ID Related Accession (Same CDS sequence)	NM_139166.5 , XM_024447063.1 , NM_139166.4
Accession Version	NM_139166.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	actin-binding Rho-activating protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL832152.1 and BC105103.1. On Nov 23, 2018 this sequence version replaced NM_139166.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL832152.1, AL833422.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000311955.4/ ENSP00000311436.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTCCGG GCGAAAAGGA AAGCGGGGAG GGCCCAGCCA AGAGCGCCCT CCGGAAGATA 
CGCACAGCCA CCCTGGTCAT CAGCTTGGCC CGAGGTTGGC AGCAGTGGGC GAATGAGAAC 
AGCATCAGGC AGGCCCAGGA GCCTACAGGC TGGCTGCCGG GAGGGACCCA GGACTCACCT 
CAAGCTCCTA AACCAATCAC ACCCCCTACT TCACACCAGA AAGCTCAGAG TGCCCCAAAG 
TCGCCACCCC GCCTGCCAGA AGGACATGGA GATGGACAAA GCTCAGAGAA AGCCCCTGAG 
GTTTCTCACA TCAAAAAGAA AGAGGTGTCC AAAACGGTGG TCAGCAAGAC TTATGAGAGA 
GGAGGGGACG TGAGCCACCT CAGCCACAGG TACGAGAGGG ATGCTGGTGT GCTTGAACCT 
GGGCAGCCAG AGAATGACAT TGACAGAATC CTCCACAGCC ACGGCTCCCC AACGCGGAGG 
AGAAAATGTG CCAACCTGGT GTCTGAGCTA ACCAAGGGCT GGAGAGTGAT GGAGCAGGAG 
GAGCCCACAT GGAGGAGTGA CAGCGTAGAC ACAGAGGACA GCGGCTATGG AGGAGAGGCT 
GAGGAGAGGC CCGAGCAGGA TGGAGTGCAG GTGGCTGTGG TCAGGATCAA GCGCCCCTTG 
CCCTCCCAGG TAAACAGATT TACAGAGAAA CTCAACTGCA AAGCCCAACA GAAATATAGC 
CCAGTGGGCA ACTTGAAAGG GAGATGGCAG CAGTGGGCTG ATGAACACAT ACAATCCCAG 
AAGCTCAATC CTTTCAGTGA AGAGTTTGAT TACGAGCTGG CCATGTCCAC CCGCCTACAC 
AAAGGAGATG AGGGCTATGG CCGCCCCAAA GAAGGAACCA AAACTGCTGA AAGGGCCAAG 
CGTGCTGAGG AGCACATCTA CAGGGAAATG ATGGACATGT GCTTCATTAT CTGCACAATG 
GCTCGCCACA GACGAGATGG CAAGATCCAG GTTACTTTTG GAGATCTCTT TGACAGATAC 
GTTCGTATTT CAGATAAAGT AGTGGGCATT CTCATGCGTG CCAGGAAACA TGGACTGGTA 
GACTTTGAAG GAGAGATGCT ATGGCAAGGC CGAGATGACC ATGTTGTGAT TACGCTACTC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_631905.1
CDS	55..1200
Translation	MAPGEKESGEGPAKSALRKIRTATLVISLARGWQQWANENSIRQAQEPTGWLPGGTQDSPQAPKPITPPTSHQKAQSAPKSPPRLPEGHGDGQSSEKAPEVSHIKKKEVSKTVVSKTYERGGDVSHLSHRYERDAGVLEPGQPENDIDRILHSHGSPTRRRKCANLVSELTKGWRVMEQEEPTWRSDSVDTEDSGYGGEAEERPEQDGVQVAVVRIKRPLPSQVNRFTEKLNCKAQQKYSPVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGTKTAERAKRAEEHIYREMMDMCFIICTMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLVDFEGEMLWQGRDDHVVITLLK

Target ORF information:

RefSeq Version	NM_139166.5
Organism	Homo sapiens(human)
Definition	Homo sapiens actin binding Rho activating protein (ABRA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139166.5

ORF Insert Sequence:

ATGGCTCCGG GCGAAAAGGA AAGCGGGGAG GGCCCAGCCA AGAGCGCCCT CCGGAAGATA 
CGCACAGCCA CCCTGGTCAT CAGCTTGGCC CGAGGTTGGC AGCAGTGGGC GAATGAGAAC 
AGCATCAGGC AGGCCCAGGA GCCTACAGGC TGGCTGCCGG GAGGGACCCA GGACTCACCT 
CAAGCTCCTA AACCAATCAC ACCCCCTACT TCACACCAGA AAGCTCAGAG TGCCCCAAAG 
TCGCCACCCC GCCTGCCAGA AGGACATGGA GATGGACAAA GCTCAGAGAA AGCCCCTGAG 
GTTTCTCACA TCAAAAAGAA AGAGGTGTCC AAAACGGTGG TCAGCAAGAC TTATGAGAGA 
GGAGGGGACG TGAGCCACCT CAGCCACAGG TACGAGAGGG ATGCTGGTGT GCTTGAACCT 
GGGCAGCCAG AGAATGACAT TGACAGAATC CTCCACAGCC ACGGCTCCCC AACGCGGAGG 
AGAAAATGTG CCAACCTGGT GTCTGAGCTA ACCAAGGGCT GGAGAGTGAT GGAGCAGGAG 
GAGCCCACAT GGAGGAGTGA CAGCGTAGAC ACAGAGGACA GCGGCTATGG AGGAGAGGCT 
GAGGAGAGGC CCGAGCAGGA TGGAGTGCAG GTGGCTGTGG TCAGGATCAA GCGCCCCTTG 
CCCTCCCAGG TAAACAGATT TACAGAGAAA CTCAACTGCA AAGCCCAACA GAAATATAGC 
CCAGTGGGCA ACTTGAAAGG GAGATGGCAG CAGTGGGCTG ATGAACACAT ACAATCCCAG 
AAGCTCAATC CTTTCAGTGA AGAGTTTGAT TACGAGCTGG CCATGTCCAC CCGCCTACAC 
AAAGGAGATG AGGGCTATGG CCGCCCCAAA GAAGGAACCA AAACTGCTGA AAGGGCCAAG 
CGTGCTGAGG AGCACATCTA CAGGGAAATG ATGGACATGT GCTTCATTAT CTGCACAATG 
GCTCGCCACA GACGAGATGG CAAGATCCAG GTTACTTTTG GAGATCTCTT TGACAGATAC 
GTTCGTATTT CAGATAAAGT AGTGGGCATT CTCATGCGTG CCAGGAAACA TGGACTGGTA 
GACTTTGAAG GAGAGATGCT ATGGCAAGGC CGAGATGACC ATGTTGTGAT TACGCTACTC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABRA ( NM_139166.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_631905.1 Homo sapiens actin binding Rho activating protein (ABRA), mRNA.

Price & Availability↑

CloneID	OHu09034
Clone ID Related Accession (Same CDS sequence)	NM_139166.5 , XM_024447063.1 , NM_139166.4
Accession Version	NM_139166.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	actin-binding Rho-activating protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL832152.1 and BC105103.1. On Jun 6, 2008 this sequence version replaced NM_139166.3. ##Evidence-Data-START## Transcript exon combination :: AL832152.1, AL833422.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGGCTCCGG GCGAAAAGGA AAGCGGGGAG GGCCCAGCCA AGAGCGCCCT CCGGAAGATA 
CGCACAGCCA CCCTGGTCAT CAGCTTGGCC CGAGGTTGGC AGCAGTGGGC GAATGAGAAC 
AGCATCAGGC AGGCCCAGGA GCCTACAGGC TGGCTGCCGG GAGGGACCCA GGACTCACCT 
CAAGCTCCTA AACCAATCAC ACCCCCTACT TCACACCAGA AAGCTCAGAG TGCCCCAAAG 
TCGCCACCCC GCCTGCCAGA AGGACATGGA GATGGACAAA GCTCAGAGAA AGCCCCTGAG 
GTTTCTCACA TCAAAAAGAA AGAGGTGTCC AAAACGGTGG TCAGCAAGAC TTATGAGAGA 
GGAGGGGACG TGAGCCACCT CAGCCACAGG TACGAGAGGG ATGCTGGTGT GCTTGAACCT 
GGGCAGCCAG AGAATGACAT TGACAGAATC CTCCACAGCC ACGGCTCCCC AACGCGGAGG 
AGAAAATGTG CCAACCTGGT GTCTGAGCTA ACCAAGGGCT GGAGAGTGAT GGAGCAGGAG 
GAGCCCACAT GGAGGAGTGA CAGCGTAGAC ACAGAGGACA GCGGCTATGG AGGAGAGGCT 
GAGGAGAGGC CCGAGCAGGA TGGAGTGCAG GTGGCTGTGG TCAGGATCAA GCGCCCCTTG 
CCCTCCCAGG TAAACAGATT TACAGAGAAA CTCAACTGCA AAGCCCAACA GAAATATAGC 
CCAGTGGGCA ACTTGAAAGG GAGATGGCAG CAGTGGGCTG ATGAACACAT ACAATCCCAG 
AAGCTCAATC CTTTCAGTGA AGAGTTTGAT TACGAGCTGG CCATGTCCAC CCGCCTACAC 
AAAGGAGATG AGGGCTATGG CCGCCCCAAA GAAGGAACCA AAACTGCTGA AAGGGCCAAG 
CGTGCTGAGG AGCACATCTA CAGGGAAATG ATGGACATGT GCTTCATTAT CTGCACAATG 
GCTCGCCACA GACGAGATGG CAAGATCCAG GTTACTTTTG GAGATCTCTT TGACAGATAC 
GTTCGTATTT CAGATAAAGT AGTGGGCATT CTCATGCGTG CCAGGAAACA TGGACTGGTA 
GACTTTGAAG GAGAGATGCT ATGGCAAGGC CGAGATGACC ATGTTGTGAT TACGCTACTC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_631905.1
CDS	55..1200
Translation	MAPGEKESGEGPAKSALRKIRTATLVISLARGWQQWANENSIRQAQEPTGWLPGGTQDSPQAPKPITPPTSHQKAQSAPKSPPRLPEGHGDGQSSEKAPEVSHIKKKEVSKTVVSKTYERGGDVSHLSHRYERDAGVLEPGQPENDIDRILHSHGSPTRRRKCANLVSELTKGWRVMEQEEPTWRSDSVDTEDSGYGGEAEERPEQDGVQVAVVRIKRPLPSQVNRFTEKLNCKAQQKYSPVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGTKTAERAKRAEEHIYREMMDMCFIICTMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLVDFEGEMLWQGRDDHVVITLLK

Target ORF information:

RefSeq Version	NM_139166.4
Organism	Homo sapiens(human)
Definition	Homo sapiens actin binding Rho activating protein (ABRA), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139166.4

ORF Insert Sequence:

ATGGCTCCGG GCGAAAAGGA AAGCGGGGAG GGCCCAGCCA AGAGCGCCCT CCGGAAGATA 
CGCACAGCCA CCCTGGTCAT CAGCTTGGCC CGAGGTTGGC AGCAGTGGGC GAATGAGAAC 
AGCATCAGGC AGGCCCAGGA GCCTACAGGC TGGCTGCCGG GAGGGACCCA GGACTCACCT 
CAAGCTCCTA AACCAATCAC ACCCCCTACT TCACACCAGA AAGCTCAGAG TGCCCCAAAG 
TCGCCACCCC GCCTGCCAGA AGGACATGGA GATGGACAAA GCTCAGAGAA AGCCCCTGAG 
GTTTCTCACA TCAAAAAGAA AGAGGTGTCC AAAACGGTGG TCAGCAAGAC TTATGAGAGA 
GGAGGGGACG TGAGCCACCT CAGCCACAGG TACGAGAGGG ATGCTGGTGT GCTTGAACCT 
GGGCAGCCAG AGAATGACAT TGACAGAATC CTCCACAGCC ACGGCTCCCC AACGCGGAGG 
AGAAAATGTG CCAACCTGGT GTCTGAGCTA ACCAAGGGCT GGAGAGTGAT GGAGCAGGAG 
GAGCCCACAT GGAGGAGTGA CAGCGTAGAC ACAGAGGACA GCGGCTATGG AGGAGAGGCT 
GAGGAGAGGC CCGAGCAGGA TGGAGTGCAG GTGGCTGTGG TCAGGATCAA GCGCCCCTTG 
CCCTCCCAGG TAAACAGATT TACAGAGAAA CTCAACTGCA AAGCCCAACA GAAATATAGC 
CCAGTGGGCA ACTTGAAAGG GAGATGGCAG CAGTGGGCTG ATGAACACAT ACAATCCCAG 
AAGCTCAATC CTTTCAGTGA AGAGTTTGAT TACGAGCTGG CCATGTCCAC CCGCCTACAC 
AAAGGAGATG AGGGCTATGG CCGCCCCAAA GAAGGAACCA AAACTGCTGA AAGGGCCAAG 
CGTGCTGAGG AGCACATCTA CAGGGAAATG ATGGACATGT GCTTCATTAT CTGCACAATG 
GCTCGCCACA GACGAGATGG CAAGATCCAG GTTACTTTTG GAGATCTCTT TGACAGATAC 
GTTCGTATTT CAGATAAAGT AGTGGGCATT CTCATGCGTG CCAGGAAACA TGGACTGGTA 
GACTTTGAAG GAGAGATGCT ATGGCAAGGC CGAGATGACC ATGTTGTGAT TACGCTACTC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ABRA ( XM_024447063.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024302831.1 Homo sapiens actin binding Rho activating protein (ABRA), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu09034
Clone ID Related Accession (Same CDS sequence)	NM_139166.5 , XM_024447063.1 , NM_139166.4
Accession Version	XM_024447063.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	actin-binding Rho-activating protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCCGG GCGAAAAGGA AAGCGGGGAG GGCCCAGCCA AGAGCGCCCT CCGGAAGATA 
CGCACAGCCA CCCTGGTCAT CAGCTTGGCC CGAGGTTGGC AGCAGTGGGC GAATGAGAAC 
AGCATCAGGC AGGCCCAGGA GCCTACAGGC TGGCTGCCGG GAGGGACCCA GGACTCACCT 
CAAGCTCCTA AACCAATCAC ACCCCCTACT TCACACCAGA AAGCTCAGAG TGCCCCAAAG 
TCGCCACCCC GCCTGCCAGA AGGACATGGA GATGGACAAA GCTCAGAGAA AGCCCCTGAG 
GTTTCTCACA TCAAAAAGAA AGAGGTGTCC AAAACGGTGG TCAGCAAGAC TTATGAGAGA 
GGAGGGGACG TGAGCCACCT CAGCCACAGG TACGAGAGGG ATGCTGGTGT GCTTGAACCT 
GGGCAGCCAG AGAATGACAT TGACAGAATC CTCCACAGCC ACGGCTCCCC AACGCGGAGG 
AGAAAATGTG CCAACCTGGT GTCTGAGCTA ACCAAGGGCT GGAGAGTGAT GGAGCAGGAG 
GAGCCCACAT GGAGGAGTGA CAGCGTAGAC ACAGAGGACA GCGGCTATGG AGGAGAGGCT 
GAGGAGAGGC CCGAGCAGGA TGGAGTGCAG GTGGCTGTGG TCAGGATCAA GCGCCCCTTG 
CCCTCCCAGG TAAACAGATT TACAGAGAAA CTCAACTGCA AAGCCCAACA GAAATATAGC 
CCAGTGGGCA ACTTGAAAGG GAGATGGCAG CAGTGGGCTG ATGAACACAT ACAATCCCAG 
AAGCTCAATC CTTTCAGTGA AGAGTTTGAT TACGAGCTGG CCATGTCCAC CCGCCTACAC 
AAAGGAGATG AGGGCTATGG CCGCCCCAAA GAAGGAACCA AAACTGCTGA AAGGGCCAAG 
CGTGCTGAGG AGCACATCTA CAGGGAAATG ATGGACATGT GCTTCATTAT CTGCACAATG 
GCTCGCCACA GACGAGATGG CAAGATCCAG GTTACTTTTG GAGATCTCTT TGACAGATAC 
GTTCGTATTT CAGATAAAGT AGTGGGCATT CTCATGCGTG CCAGGAAACA TGGACTGGTA 
GACTTTGAAG GAGAGATGCT ATGGCAAGGC CGAGATGACC ATGTTGTGAT TACGCTACTC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024302831.1
CDS	208..1353
Translation	MAPGEKESGEGPAKSALRKIRTATLVISLARGWQQWANENSIRQAQEPTGWLPGGTQDSPQAPKPITPPTSHQKAQSAPKSPPRLPEGHGDGQSSEKAPEVSHIKKKEVSKTVVSKTYERGGDVSHLSHRYERDAGVLEPGQPENDIDRILHSHGSPTRRRKCANLVSELTKGWRVMEQEEPTWRSDSVDTEDSGYGGEAEERPEQDGVQVAVVRIKRPLPSQVNRFTEKLNCKAQQKYSPVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGTKTAERAKRAEEHIYREMMDMCFIICTMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLVDFEGEMLWQGRDDHVVITLLK

Target ORF information:

RefSeq Version	XM_024447063.1
Organism	Homo sapiens(human)
Definition	Homo sapiens actin binding Rho activating protein (ABRA), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024447063.1

ORF Insert Sequence:

ATGGCTCCGG GCGAAAAGGA AAGCGGGGAG GGCCCAGCCA AGAGCGCCCT CCGGAAGATA 
CGCACAGCCA CCCTGGTCAT CAGCTTGGCC CGAGGTTGGC AGCAGTGGGC GAATGAGAAC 
AGCATCAGGC AGGCCCAGGA GCCTACAGGC TGGCTGCCGG GAGGGACCCA GGACTCACCT 
CAAGCTCCTA AACCAATCAC ACCCCCTACT TCACACCAGA AAGCTCAGAG TGCCCCAAAG 
TCGCCACCCC GCCTGCCAGA AGGACATGGA GATGGACAAA GCTCAGAGAA AGCCCCTGAG 
GTTTCTCACA TCAAAAAGAA AGAGGTGTCC AAAACGGTGG TCAGCAAGAC TTATGAGAGA 
GGAGGGGACG TGAGCCACCT CAGCCACAGG TACGAGAGGG ATGCTGGTGT GCTTGAACCT 
GGGCAGCCAG AGAATGACAT TGACAGAATC CTCCACAGCC ACGGCTCCCC AACGCGGAGG 
AGAAAATGTG CCAACCTGGT GTCTGAGCTA ACCAAGGGCT GGAGAGTGAT GGAGCAGGAG 
GAGCCCACAT GGAGGAGTGA CAGCGTAGAC ACAGAGGACA GCGGCTATGG AGGAGAGGCT 
GAGGAGAGGC CCGAGCAGGA TGGAGTGCAG GTGGCTGTGG TCAGGATCAA GCGCCCCTTG 
CCCTCCCAGG TAAACAGATT TACAGAGAAA CTCAACTGCA AAGCCCAACA GAAATATAGC 
CCAGTGGGCA ACTTGAAAGG GAGATGGCAG CAGTGGGCTG ATGAACACAT ACAATCCCAG 
AAGCTCAATC CTTTCAGTGA AGAGTTTGAT TACGAGCTGG CCATGTCCAC CCGCCTACAC 
AAAGGAGATG AGGGCTATGG CCGCCCCAAA GAAGGAACCA AAACTGCTGA AAGGGCCAAG 
CGTGCTGAGG AGCACATCTA CAGGGAAATG ATGGACATGT GCTTCATTAT CTGCACAATG 
GCTCGCCACA GACGAGATGG CAAGATCCAG GTTACTTTTG GAGATCTCTT TGACAGATAC 
GTTCGTATTT CAGATAAAGT AGTGGGCATT CTCATGCGTG CCAGGAAACA TGGACTGGTA 
GACTTTGAAG GAGAGATGCT ATGGCAAGGC CGAGATGACC ATGTTGTGAT TACGCTACTC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Striated muscle activator of Rho signalling (STARS) is reduced in ageing human skeletal muscle and targeted by miR-628-5p.
Acta physiologica (Oxford, England)220(2)263-274(2017 Jun)
Russell AP,Wallace MA,Kalanon M,Zacharewicz E,Della Gatta PA,Garnham A,Lamon S

Identification of striated muscle activator of Rho signaling (STARS) as a novel calmodulin target by a newly developed genome-wide screen.
Cell calcium60(1)32-40(2016 Jul)
Furuya Y,Denda M,Sakane K,Ogusu T,Takahashi S,Magari M,Kanayama N,Morishita R,Tokumitsu H

Effect of resistance exercise contraction mode and protein supplementation on members of the STARS signalling pathway.
The Journal of physiology591(15)3749-63(2013 Aug)
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ABRA cDNA ORF clone, Homo sapiens(human)

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