TRAM1L1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TRAM1L1
Entrez Gene ID	133022
Full Name	translocation associated membrane protein 1 like 1
General protein information	Preferred Names translocation associated membrane protein 1 like 1 Names translocating chain-associated membrane protein 1-like 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q26
Disorder MIM:	617505

mRNA and Protein(s)

mRNA	Protein	Name
NM_152402.2	NP_689615.2	translocating chain-associated membrane protein 1-like 1
NM_152402.3	NP_689615.2	translocating chain-associated membrane protein 1-like 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	TRAM1L1	NP_689615.2
Mus musculus (house mouse)	Tram1l1	NP_666252.1
Canis lupus familiaris (dog)	TRAM1L1	XP_005639371.1
Bos taurus (cattle)	TRAM1L1	XP_002688113.1
Pan troglodytes (chimpanzee)	TRAM1L1	XP_526671.2
	TRAM1L1	XP_001097744.1
Rattus norvegicus (Norway rat)	Tram1l1	NP_001101194.1

Gene Ontology
Bibliography

Related articles in PubMed

A genome-wide association study (GWAS) for bronchopulmonary dysplasia.
Wang H, St Julien KR, Stevenson DK, Hoffmann TJ, Witte JS, Lazzeroni LC, Krasnow MA, Quaintance CC, Oehlert JW, Jelliffe-Pawlowski LL, Gould JB, Shaw GM, O'Brodovich HM
Pediatrics132(2)290-7(2013 Aug)

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
Fox CS, Liu Y, White CC, Feitosa M, Smith AV, Heard-Costa N, Lohman K, , , , Johnson AD, Foster MC, Greenawalt DM, Griffin P, Ding J, Newman AB, Tylavsky F, Miljkovic I, Kritchevsky SB, Launer L, Garcia M, Eiriksdottir G, Carr JJ, Gudnason V, Harris TB, Cupples LA, Borecki IB
PLoS genetics8(5)e1002695(2012)

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J Jr, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP
Human molecular genetics19(12)2497-506(2010 Jun)

Common body mass index-associated variants confer risk of extreme obesity.
Cotsapas C, Speliotes EK, Hatoum IJ, Greenawalt DM, Dobrin R, Lum PY, Suver C, Chudin E, Kemp D, Reitman M, Voight BF, Neale BM, Schadt EE, Hirschhorn JN, Kaplan LM, Daly MJ,
Human molecular genetics18(18)3502-7(2009 Sep)

TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis.
Stefanovic B, Stefanovic L, Schnabl B, Bataller R, Brenner DA
Molecular and cellular biology24(4)1758-68(2004 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.

The following TRAM1L1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRAM1L1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55944	NM_152402.3 Latest version!	Homo sapiens translocation associated membrane protein 1 like 1 (TRAM1L1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu55944	NM_152402.2	Homo sapiens translocation associated membrane protein 1 like 1 (TRAM1L1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TRAM1L1 ( NM_152402.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_689615.2 Homo sapiens translocation associated membrane protein 1 like 1 (TRAM1L1), mRNA.

Price & Availability↑

CloneID	OHu55944
Clone ID Related Accession (Same CDS sequence)	NM_152402.2 , NM_152402.3
Accession Version	NM_152402.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	translocating chain-associated membrane protein 1-like 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB099839.1, BX423039.2, BC030831.1 and CA415689.1. On Apr 20, 2007 this sequence version replaced NM_152402.1. ##Evidence-Data-START## Transcript is intronless :: BC030831.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCTCC GTAAGAAGAG CACCAAGAAC CCCCCCGTTC TCAGCCAGGA ATTCATCCTG 
CAGAATCATG CGGACATCGT CTCCTGCGTG GGGATGTTCT TCCTGCTGGG GCTTGTGTTC 
GAGGGAACAG CAGAAGCATC CATCGTGTTT CTCACTCTTC AGCACAGTGT TGCTGTCCCT 
GCAGCAGAGG AACAAGCCAC GGGCTCAAAG TCCCTCTATT ATTATGGTGT CAAAGATTTG 
GCCACGGTTT TCTTCTACAT GCTGGTGGCA ATCATTATTC ATGCCACAAT TCAGGAATAT 
GTGTTGGATA AAATTAACAA GAGAATGCAG TTCACCAAAG CGAAACAAAA CAAGTTTAAC 
GAGTCTGGTC AGTTTAGTGT GTTCTACTTT TTTTCTTGTA TTTGGGGCAC ATTCATTTTA 
ATCTCTGAAA ACTGCCTGTC AGACCCAACT CTTATATGGA AGGCTCGTCC CCATAGCATG 
ATGACATTTC AAATGAAGTT TTTCTACATA TCCCAGTTGG CTTACTGGTT TCATGCTTTT 
CCTGAACTCT ACTTCCAGAA AACCAAAAAA CAAGACATCC CTCGTCAACT TGTCTACATT 
GGTCTTCACC TCTTCCACAT TACTGGAGCT TATCTCTTGT ACTTGAATCA TTTGGGACTT 
CTTCTTTTGG TACTGCATTA TTTTGTTGAA TTACTTTCCC ACATGTGCGG CCTGTTTTAC 
TTTAGTGATG AAAAGTACCA GAAAGGCATA TCTCTGTGGG CCATTGTGTT TATCTTGGGT 
AGACTTGTGA CTTTAATTGT TTCCGTACTC ACTGTTGGGT TTCACCTGGC TGGATCGCAG 
AATCGGAATC CTGATGCCCT TACTGGAAAT GTAAATGTGT TGGCAGCTAA AATTGCTGTT 
CTGTCGTCCA GTTGCACGAT CCAAGCCTAC GTAACATGGA ACTTAATTAC TCTCTGGCTT 
CAGAGGTGGG TAGAAGATTC TAATATTCAG GCCTCATGTA TGAAAAAGAA ACGGTCGAGA 
TCTTCTAAAA AAAGAACAGA AAACGGAGTG GGAGTGGAAA CTTCAAATAG AGTAGACTGT 
CCGCCAAAGA GGAAAGAGAA ATCTTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_689615.2
CDS	188..1297
Translation	MGLRKKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVPAAEEQATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFYFSDEKYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAVLSSSCTIQAYVTWNLITLWLQRWVEDSNIQASCMKKKRSRSSKKRTENGVGVETSNRVDCPPKRKEKSS

Target ORF information:

RefSeq Version	NM_152402.2
Organism	Homo sapiens(human)
Definition	Homo sapiens translocation associated membrane protein 1 like 1 (TRAM1L1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152402.2

ORF Insert Sequence:

ATGGGGCTCC GTAAGAAGAG CACCAAGAAC CCCCCCGTTC TCAGCCAGGA ATTCATCCTG 
CAGAATCATG CGGACATCGT CTCCTGCGTG GGGATGTTCT TCCTGCTGGG GCTTGTGTTC 
GAGGGAACAG CAGAAGCATC CATCGTGTTT CTCACTCTTC AGCACAGTGT TGCTGTCCCT 
GCAGCAGAGG AACAAGCCAC GGGCTCAAAG TCCCTCTATT ATTATGGTGT CAAAGATTTG 
GCCACGGTTT TCTTCTACAT GCTGGTGGCA ATCATTATTC ATGCCACAAT TCAGGAATAT 
GTGTTGGATA AAATTAACAA GAGAATGCAG TTCACCAAAG CGAAACAAAA CAAGTTTAAC 
GAGTCTGGTC AGTTTAGTGT GTTCTACTTT TTTTCTTGTA TTTGGGGCAC ATTCATTTTA 
ATCTCTGAAA ACTGCCTGTC AGACCCAACT CTTATATGGA AGGCTCGTCC CCATAGCATG 
ATGACATTTC AAATGAAGTT TTTCTACATA TCCCAGTTGG CTTACTGGTT TCATGCTTTT 
CCTGAACTCT ACTTCCAGAA AACCAAAAAA CAAGACATCC CTCGTCAACT TGTCTACATT 
GGTCTTCACC TCTTCCACAT TACTGGAGCT TATCTCTTGT ACTTGAATCA TTTGGGACTT 
CTTCTTTTGG TACTGCATTA TTTTGTTGAA TTACTTTCCC ACATGTGCGG CCTGTTTTAC 
TTTAGTGATG AAAAGTACCA GAAAGGCATA TCTCTGTGGG CCATTGTGTT TATCTTGGGT 
AGACTTGTGA CTTTAATTGT TTCCGTACTC ACTGTTGGGT TTCACCTGGC TGGATCGCAG 
AATCGGAATC CTGATGCCCT TACTGGAAAT GTAAATGTGT TGGCAGCTAA AATTGCTGTT 
CTGTCGTCCA GTTGCACGAT CCAAGCCTAC GTAACATGGA ACTTAATTAC TCTCTGGCTT 
CAGAGGTGGG TAGAAGATTC TAATATTCAG GCCTCATGTA TGAAAAAGAA ACGGTCGAGA 
TCTTCTAAAA AAAGAACAGA AAACGGAGTG GGAGTGGAAA CTTCAAATAG AGTAGACTGT 
CCGCCAAAGA GGAAAGAGAA ATCTTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TRAM1L1 ( NM_152402.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_689615.2 Homo sapiens translocation associated membrane protein 1 like 1 (TRAM1L1), mRNA.

Price & Availability↑

CloneID	OHu55944
Clone ID Related Accession (Same CDS sequence)	NM_152402.2 , NM_152402.3
Accession Version	NM_152402.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-29
Organism	Homo sapiens(human)
Product	translocating chain-associated membrane protein 1-like 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB099839.1, BX423039.2, BC030831.1 and CA415689.1. On May 17, 2019 this sequence version replaced NM_152402.2. ##Evidence-Data-START## Transcript is intronless :: BC030831.1, AK074617.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000310754.5/ ENSP00000309402.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGCTCC GTAAGAAGAG CACCAAGAAC CCCCCCGTTC TCAGCCAGGA ATTCATCCTG 
CAGAATCATG CGGACATCGT CTCCTGCGTG GGGATGTTCT TCCTGCTGGG GCTTGTGTTC 
GAGGGAACAG CAGAAGCATC CATCGTGTTT CTCACTCTTC AGCACAGTGT TGCTGTCCCT 
GCAGCAGAGG AACAAGCCAC GGGCTCAAAG TCCCTCTATT ATTATGGTGT CAAAGATTTG 
GCCACGGTTT TCTTCTACAT GCTGGTGGCA ATCATTATTC ATGCCACAAT TCAGGAATAT 
GTGTTGGATA AAATTAACAA GAGAATGCAG TTCACCAAAG CGAAACAAAA CAAGTTTAAC 
GAGTCTGGTC AGTTTAGTGT GTTCTACTTT TTTTCTTGTA TTTGGGGCAC ATTCATTTTA 
ATCTCTGAAA ACTGCCTGTC AGACCCAACT CTTATATGGA AGGCTCGTCC CCATAGCATG 
ATGACATTTC AAATGAAGTT TTTCTACATA TCCCAGTTGG CTTACTGGTT TCATGCTTTT 
CCTGAACTCT ACTTCCAGAA AACCAAAAAA CAAGACATCC CTCGTCAACT TGTCTACATT 
GGTCTTCACC TCTTCCACAT TACTGGAGCT TATCTCTTGT ACTTGAATCA TTTGGGACTT 
CTTCTTTTGG TACTGCATTA TTTTGTTGAA TTACTTTCCC ACATGTGCGG CCTGTTTTAC 
TTTAGTGATG AAAAGTACCA GAAAGGCATA TCTCTGTGGG CCATTGTGTT TATCTTGGGT 
AGACTTGTGA CTTTAATTGT TTCCGTACTC ACTGTTGGGT TTCACCTGGC TGGATCGCAG 
AATCGGAATC CTGATGCCCT TACTGGAAAT GTAAATGTGT TGGCAGCTAA AATTGCTGTT 
CTGTCGTCCA GTTGCACGAT CCAAGCCTAC GTAACATGGA ACTTAATTAC TCTCTGGCTT 
CAGAGGTGGG TAGAAGATTC TAATATTCAG GCCTCATGTA TGAAAAAGAA ACGGTCGAGA 
TCTTCTAAAA AAAGAACAGA AAACGGAGTG GGAGTGGAAA CTTCAAATAG AGTAGACTGT 
CCGCCAAAGA GGAAAGAGAA ATCTTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_689615.2
CDS	184..1293
Translation	MGLRKKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVPAAEEQATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFYFSDEKYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAVLSSSCTIQAYVTWNLITLWLQRWVEDSNIQASCMKKKRSRSSKKRTENGVGVETSNRVDCPPKRKEKSS

Target ORF information:

RefSeq Version	NM_152402.3
Organism	Homo sapiens(human)
Definition	Homo sapiens translocation associated membrane protein 1 like 1 (TRAM1L1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152402.3

ORF Insert Sequence:

ATGGGGCTCC GTAAGAAGAG CACCAAGAAC CCCCCCGTTC TCAGCCAGGA ATTCATCCTG 
CAGAATCATG CGGACATCGT CTCCTGCGTG GGGATGTTCT TCCTGCTGGG GCTTGTGTTC 
GAGGGAACAG CAGAAGCATC CATCGTGTTT CTCACTCTTC AGCACAGTGT TGCTGTCCCT 
GCAGCAGAGG AACAAGCCAC GGGCTCAAAG TCCCTCTATT ATTATGGTGT CAAAGATTTG 
GCCACGGTTT TCTTCTACAT GCTGGTGGCA ATCATTATTC ATGCCACAAT TCAGGAATAT 
GTGTTGGATA AAATTAACAA GAGAATGCAG TTCACCAAAG CGAAACAAAA CAAGTTTAAC 
GAGTCTGGTC AGTTTAGTGT GTTCTACTTT TTTTCTTGTA TTTGGGGCAC ATTCATTTTA 
ATCTCTGAAA ACTGCCTGTC AGACCCAACT CTTATATGGA AGGCTCGTCC CCATAGCATG 
ATGACATTTC AAATGAAGTT TTTCTACATA TCCCAGTTGG CTTACTGGTT TCATGCTTTT 
CCTGAACTCT ACTTCCAGAA AACCAAAAAA CAAGACATCC CTCGTCAACT TGTCTACATT 
GGTCTTCACC TCTTCCACAT TACTGGAGCT TATCTCTTGT ACTTGAATCA TTTGGGACTT 
CTTCTTTTGG TACTGCATTA TTTTGTTGAA TTACTTTCCC ACATGTGCGG CCTGTTTTAC 
TTTAGTGATG AAAAGTACCA GAAAGGCATA TCTCTGTGGG CCATTGTGTT TATCTTGGGT 
AGACTTGTGA CTTTAATTGT TTCCGTACTC ACTGTTGGGT TTCACCTGGC TGGATCGCAG 
AATCGGAATC CTGATGCCCT TACTGGAAAT GTAAATGTGT TGGCAGCTAA AATTGCTGTT 
CTGTCGTCCA GTTGCACGAT CCAAGCCTAC GTAACATGGA ACTTAATTAC TCTCTGGCTT 
CAGAGGTGGG TAGAAGATTC TAATATTCAG GCCTCATGTA TGAAAAAGAA ACGGTCGAGA 
TCTTCTAAAA AAAGAACAGA AAACGGAGTG GGAGTGGAAA CTTCAAATAG AGTAGACTGT 
CCGCCAAAGA GGAAAGAGAA ATCTTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A genome-wide association study (GWAS) for bronchopulmonary dysplasia.
Pediatrics132(2)290-7(2013 Aug)
Wang H,St Julien KR,Stevenson DK,Hoffmann TJ,Witte JS,Lazzeroni LC,Krasnow MA,Quaintance CC,Oehlert JW,Jelliffe-Pawlowski LL,Gould JB,Shaw GM,O'Brodovich HM

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
PLoS genetics8(5)e1002695(2012)
Fox CS,Liu Y,White CC,Feitosa M,Smith AV,Heard-Costa N,Lohman K,,,,Johnson AD,Foster MC,Greenawalt DM,Griffin P,Ding J,Newman AB,Tylavsky F,Miljkovic I,Kritchevsky SB,Launer L,Garcia M,Eiriksdottir G,Carr JJ,Gudnason V,Harris TB,Cupples LA,Borecki IB

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Human molecular genetics19(12)2497-506(2010 Jun)
Kalsi G,Kuo PH,Aliev F,Alexander J,McMichael O,Patterson DG,Walsh D,Zhao Z,Schuckit M,Nurnberger J Jr,Edenberg H,Kramer J,Hesselbrock V,Tischfield JA,Vladimirov V,Prescott CA,Dick DM,Kendler KS,Riley BP

Common body mass index-associated variants confer risk of extreme obesity.
Human molecular genetics18(18)3502-7(2009 Sep)
Cotsapas C,Speliotes EK,Hatoum IJ,Greenawalt DM,Dobrin R,Lum PY,Suver C,Chudin E,Kemp D,Reitman M,Voight BF,Neale BM,Schadt EE,Hirschhorn JN,Kaplan LM,Daly MJ,

TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis.
Molecular and cellular biology24(4)1758-68(2004 Feb)
Stefanovic B,Stefanovic L,Schnabl B,Bataller R,Brenner DA

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TRAM1L1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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