RPTN cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RPTN
Entrez Gene ID	126638
Full Name	repetin
General protein information	Preferred Names repetin Names repetin intermediate filament-associated protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q21.3
Disorder MIM:	613259

mRNA and Protein(s)

mRNA	Protein	Name
NM_001122965.1	NP_001116437.1	repetin

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	RPTN	XP_003432327.1
Mus musculus (house mouse)	Rptn	NP_033126.2
Homo sapiens (human)	RPTN	NP_001116437.1
Rattus norvegicus (Norway rat)	Rptn	XP_227371.1
	RPTN	XP_002801848.1
Bos taurus (cattle)	RPTN	XP_002686117.2

Gene Ontology
Bibliography

Related articles in PubMed

Altered Expression of Genes Encoding Cornulin and Repetin in Atopic Dermatitis.
Trzeciak M, Sakowicz-Burkiewicz M, Wesserling M, Gle? J, Dobaczewska D, Bandurski T, Nowicki R, Pawelczyk T
International archives of allergy and immunology172(1)11-19(2017)

Diminished serum repetin levels in patients with schizophrenia and bipolar disorder.
Wang S, Ren H, Xu J, Yu Y, Han S, Qiao H, Cheng S, Xu C, An S, Ju B, Yu C, Wang C, Wang T, Yang Z, Taylor EW, Zhao L
Scientific reports57977(2015 Jan)

Isolation and characterization of human repetin, a member of the fused gene family of the epidermal differentiation complex.
Huber M, Siegenthaler G, Mirancea N, Marenholz I, Nizetic D, Breitkreutz D, Mischke D, Hohl D
The Journal of investigative dermatology124(5)998-1007(2005 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The single-nucleotide polymorphisms of CRNN (rs941934) and RPTN (rs3001978, rs28441202) may contribute to Atopic Dermatitis development, but further studies on a larger group of Atopic Dermatitis patients are needed to verify this assumption.
Title: Altered Expression of Genes Encoding Cornulin and Repetin in Atopic Dermatitis.

RPTN plays a potential role in emotional and cognitive processing; its decrease in serum may indicate its involvement in the pathogenesis of schizophrenia and bipolar disorder
Title: Diminished serum repetin levels in patients with schizophrenia and bipolar disorder.

The following RPTN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPTN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu31826	NM_001122965.1 Latest version!	Homo sapiens repetin (RPTN), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RPTN ( NM_001122965.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001116437.1 Homo sapiens repetin (RPTN), mRNA.

Price & Availability↑

CloneID	OHu31826
Clone ID Related Accession (Same CDS sequence)	NM_001122965.1
Accession Version	NM_001122965.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2355bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Homo sapiens(human)
Product	repetin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY396742.1. On or before Apr 4, 2008 this sequence version replaced XM_937200.2, XM_001721513.1, XM_001724407.1. ##Evidence-Data-START## Transcript exon combination :: AY396742.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000316073.3/ ENSP00000317895.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGCTCAAC TCCTGAATAG CATACTCAGT GTGATTGACG TATTCCACAA ATATGCCAAA 
GGGAATGGGG ACTGTGCCTT ACTATGCAAG GAAGAGTTGA AACAACTGCT CTTGGCTGAG 
TTTGGAGACA TCCTCCAGAG ACCAAATGAC CCAGAGACTG TGGAAACCAT CTTGAACCTC 
TTAGATCAAG ACCGAGATGG ACATATTGAT TTTCATGAGT ACCTCTTGTT GGTGTTCCAG 
TTGGTCCAAG CCTGCTATCA TAAGCTAGAC AATAAGTCAC ATGGAGGCAG GACCTCACAG 
CAAGAAAGGG GGCAGGAAGG AGCACAAGAC TGTAAGTTCC CAGGAAACAC AGGCAGACAA 
CACAGACAGA GGCACGAGGA AGAAAGGCAG AACTCCCACC ACAGTCAGCC TGAGAGACAA 
GACGGAGATT CCCACCATGG TCAGCCTGAG AGACAAGACA GAGATTCCCA CCATGGTCAG 
TCTGAGAAAC AAGACAGAGA TTCCCACCAC AGTCAGCCTG AGAGACAAGA CAGAGATTCT 
CACCACAATC AGTCTGAGAG ACAAGACAAG GATTTCAGCT TTGATCAGTC AGAGAGACAA 
AGTCAAGACT CCAGCTCTGG TAAAAAAGTG AGTCACAAAT CTACCAGTGG CCAGGCTAAA 
TGGCAGGGAC ATATCTTTGC CTTAAATCGG TGTGAAAAAC CAATTCAGGA TTCTCATTAT 
GGTCAGTCTG AAAGACATAC ACAACAATCT GAAACACTTG GACAAGCCTC TCACTTTAAC 
CAGACAAATC AACAGAAATC AGGCTCTTAT TGTGGACAGT CTGAGAGGCT AGGTCAGGAA 
TTAGGCTGTG GTCAGACAGA CAGACAAGGC CAGAGTTCCC ACTACGGTCA GACGGACAGA 
CAAGACCAGA GTTATCATTA TGGTCAGACA GACAGACAAG GCCAGAGTTC CCACTACAGT 
CAGACGGACA GACAAGGCCA GAGTTCCCAC TACAGTCAGC CAGACAGACA AGGTCAGAGT 
TCCCACTATG GTCAAATGGA CAGAAAAGGC CAGTGTTATC ATTATGATCA GACAAACAGA 
CAAGGCCAGG GTTCCCACTA CAGTCAACCA AACAGACAAG GTCAGAGTTC CCACTATGGT 
CAGCCAGACA CACAAGATCA GAGTTCTCAC TATGGTCAGA CAGACAGACA AGACCAAAGT 
TCTCACTATG GTCAGACAGA GAGACAAGGC CAGAGTTCCC ACTACAGTCA GATGGACCGA 
CAAGGCCAGG GTTCTCACTA CGGTCAGACA GACAGACAAG GCCAGAGTTC CCACTATGGT 
CAGCCAGACA GACAAGGCCA GAATTCCCAC TATGGTCAGA CAGACAGACA AGGCCAGAGT 
TCCCACTATG GTCAGACAGA CAGACAAGGC CAGAGTTCCC ACTACAGTCA GCCAGACAAA 
CAAGGCCAGA GTTCCCACTA TGGTAAGATA GACAGACAAG ACCAGAGTTA TCATTATGGT 
CAGCCAGACG GACAAGGCCA AAGTTCCCAC TATGGTCAGA CAGACAGACA AGGCCAGAGT 
TTCCACTATG GTCAGCCAGA CAGACAAGGC CAGAGTTCCC ACTACAGTCA GATGGACAGA 
CAAGGCCAGA GTTCCCACTA TGGTCAGACA GACAGACAAG GCCAGAGTTC CCACTACGGT 
CAGACAGACA GACAAGGCCA GAGCTATCAT TATGGTCAGA CAGACAGACA AGGCCAGAGT 
TCCCACTATA TTCAATCACA GACTGGGGAA ATACAAGGGC AAAATAAGTA CTTCCAAGGG 
ACTGAAGGAA CAAGAAAAGC CTCTTATGTT GAACAATCAG GAAGATCAGG GAGGCTAAGT 
CAACAGACTC CAGGACAGGA AGGGTACCAA AACCAGGGAC AGGGATTCCA GTCTAGGGAC 
TCACAGCAGA ACGGCCACCA GGTATGGGAG CCTGAAGAGG ATAGCCAACA TCACCAACAC 
AAACTCTTAG CACAAATCCA ACAAGAAAGA CCACTTTGTC ACAAAGGGAG AGACTGGCAA 
TCATGCAGTA GTGAGCAGGG CCACAGACAG GCCCAGACCA GGCAGAGTCA TGGTGAGGGG 
CTGAGCCACT GGGCAGAGGA AGAGCAGGGC CATCAAACTT GGGATAGACA CAGCCATGAG 
AGTCAGGAAG GTCCATGTGG GACACAGGAC AGGCGAACCC ATAAAGATGA GCAGAACCAT 
CAGAGACGAG ACAGACAAAC CCATGAACAT GAGCAGAGCC ATCAGAGACG AGACAGGCAA 
ACCCATGAAG ACAAGCAGAA CCGTCAGAGA CGAGACAGGC AAACCCATGA AGACGAGCAG 
AACCATCAGA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001116437.1
CDS	66..2420
Translation	MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNLLDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQSEKQDRDSHHSQPERQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNRQRRDRQTHEDEQNHQR

Target ORF information:

RefSeq Version	NM_001122965.1
Organism	Homo sapiens(human)
Definition	Homo sapiens repetin (RPTN), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001122965.1

ORF Insert Sequence:

ATGGCTCAAC TCCTGAATAG CATACTCAGT GTGATTGACG TATTCCACAA ATATGCCAAA 
GGGAATGGGG ACTGTGCCTT ACTATGCAAG GAAGAGTTGA AACAACTGCT CTTGGCTGAG 
TTTGGAGACA TCCTCCAGAG ACCAAATGAC CCAGAGACTG TGGAAACCAT CTTGAACCTC 
TTAGATCAAG ACCGAGATGG ACATATTGAT TTTCATGAGT ACCTCTTGTT GGTGTTCCAG 
TTGGTCCAAG CCTGCTATCA TAAGCTAGAC AATAAGTCAC ATGGAGGCAG GACCTCACAG 
CAAGAAAGGG GGCAGGAAGG AGCACAAGAC TGTAAGTTCC CAGGAAACAC AGGCAGACAA 
CACAGACAGA GGCACGAGGA AGAAAGGCAG AACTCCCACC ACAGTCAGCC TGAGAGACAA 
GACGGAGATT CCCACCATGG TCAGCCTGAG AGACAAGACA GAGATTCCCA CCATGGTCAG 
TCTGAGAAAC AAGACAGAGA TTCCCACCAC AGTCAGCCTG AGAGACAAGA CAGAGATTCT 
CACCACAATC AGTCTGAGAG ACAAGACAAG GATTTCAGCT TTGATCAGTC AGAGAGACAA 
AGTCAAGACT CCAGCTCTGG TAAAAAAGTG AGTCACAAAT CTACCAGTGG CCAGGCTAAA 
TGGCAGGGAC ATATCTTTGC CTTAAATCGG TGTGAAAAAC CAATTCAGGA TTCTCATTAT 
GGTCAGTCTG AAAGACATAC ACAACAATCT GAAACACTTG GACAAGCCTC TCACTTTAAC 
CAGACAAATC AACAGAAATC AGGCTCTTAT TGTGGACAGT CTGAGAGGCT AGGTCAGGAA 
TTAGGCTGTG GTCAGACAGA CAGACAAGGC CAGAGTTCCC ACTACGGTCA GACGGACAGA 
CAAGACCAGA GTTATCATTA TGGTCAGACA GACAGACAAG GCCAGAGTTC CCACTACAGT 
CAGACGGACA GACAAGGCCA GAGTTCCCAC TACAGTCAGC CAGACAGACA AGGTCAGAGT 
TCCCACTATG GTCAAATGGA CAGAAAAGGC CAGTGTTATC ATTATGATCA GACAAACAGA 
CAAGGCCAGG GTTCCCACTA CAGTCAACCA AACAGACAAG GTCAGAGTTC CCACTATGGT 
CAGCCAGACA CACAAGATCA GAGTTCTCAC TATGGTCAGA CAGACAGACA AGACCAAAGT 
TCTCACTATG GTCAGACAGA GAGACAAGGC CAGAGTTCCC ACTACAGTCA GATGGACCGA 
CAAGGCCAGG GTTCTCACTA CGGTCAGACA GACAGACAAG GCCAGAGTTC CCACTATGGT 
CAGCCAGACA GACAAGGCCA GAATTCCCAC TATGGTCAGA CAGACAGACA AGGCCAGAGT 
TCCCACTATG GTCAGACAGA CAGACAAGGC CAGAGTTCCC ACTACAGTCA GCCAGACAAA 
CAAGGCCAGA GTTCCCACTA TGGTAAGATA GACAGACAAG ACCAGAGTTA TCATTATGGT 
CAGCCAGACG GACAAGGCCA AAGTTCCCAC TATGGTCAGA CAGACAGACA AGGCCAGAGT 
TTCCACTATG GTCAGCCAGA CAGACAAGGC CAGAGTTCCC ACTACAGTCA GATGGACAGA 
CAAGGCCAGA GTTCCCACTA TGGTCAGACA GACAGACAAG GCCAGAGTTC CCACTACGGT 
CAGACAGACA GACAAGGCCA GAGCTATCAT TATGGTCAGA CAGACAGACA AGGCCAGAGT 
TCCCACTATA TTCAATCACA GACTGGGGAA ATACAAGGGC AAAATAAGTA CTTCCAAGGG 
ACTGAAGGAA CAAGAAAAGC CTCTTATGTT GAACAATCAG GAAGATCAGG GAGGCTAAGT 
CAACAGACTC CAGGACAGGA AGGGTACCAA AACCAGGGAC AGGGATTCCA GTCTAGGGAC 
TCACAGCAGA ACGGCCACCA GGTATGGGAG CCTGAAGAGG ATAGCCAACA TCACCAACAC 
AAACTCTTAG CACAAATCCA ACAAGAAAGA CCACTTTGTC ACAAAGGGAG AGACTGGCAA 
TCATGCAGTA GTGAGCAGGG CCACAGACAG GCCCAGACCA GGCAGAGTCA TGGTGAGGGG 
CTGAGCCACT GGGCAGAGGA AGAGCAGGGC CATCAAACTT GGGATAGACA CAGCCATGAG 
AGTCAGGAAG GTCCATGTGG GACACAGGAC AGGCGAACCC ATAAAGATGA GCAGAACCAT 
CAGAGACGAG ACAGACAAAC CCATGAACAT GAGCAGAGCC ATCAGAGACG AGACAGGCAA 
ACCCATGAAG ACAAGCAGAA CCGTCAGAGA CGAGACAGGC AAACCCATGA AGACGAGCAG 
AACCATCAGA GATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Altered Expression of Genes Encoding Cornulin and Repetin in Atopic Dermatitis.
International archives of allergy and immunology172(1)11-19(2017)
Trzeciak M,Sakowicz-Burkiewicz M,Wesserling M,Gle? J,Dobaczewska D,Bandurski T,Nowicki R,Pawelczyk T

Diminished serum repetin levels in patients with schizophrenia and bipolar disorder.
Scientific reports57977(2015 Jan)
Wang S,Ren H,Xu J,Yu Y,Han S,Qiao H,Cheng S,Xu C,An S,Ju B,Yu C,Wang C,Wang T,Yang Z,Taylor EW,Zhao L

Isolation and characterization of human repetin, a member of the fused gene family of the epidermal differentiation complex.
The Journal of investigative dermatology124(5)998-1007(2005 May)
Huber M,Siegenthaler G,Mirancea N,Marenholz I,Nizetic D,Breitkreutz D,Mischke D,Hohl D

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RPTN cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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