TMIGD2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMIGD2
Entrez Gene ID	126259
Full Name	transmembrane and immunoglobulin domain containing 2
Synonyms	CD28H,IGPR-1,IGPR1
General protein information	Preferred Names transmembrane and immunoglobulin domain containing 2 Names transmembrane and immunoglobulin domain-containing protein 2 CD28 homolog CD28 homologue immunoglobulin and proline-rich receptor 1 immunoglobulin-containing and proline-rich receptor 1 transmembrane and immunoglobulin domain-containing protein 2 variant 2 transmembrane and immunoglobulin domain-containing protein 2 variant 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.3
Disorder MIM:	614715

mRNA and Protein(s)

mRNA	Protein	Name
NM_001308232.1	NP_001295161.1	transmembrane and immunoglobulin domain-containing protein 2 isoform 3
NM_001169126.1	NP_001162597.1	transmembrane and immunoglobulin domain-containing protein 2 isoform 2 precursor
XM_024451359.1	XP_024307127.1	transmembrane and immunoglobulin domain-containing protein 2 isoform X2
XM_017026284.1	XP_016881773.1	transmembrane and immunoglobulin domain-containing protein 2 isoform X1
NM_144615.2	NP_653216.2	transmembrane and immunoglobulin domain-containing protein 2 isoform 1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TMIGD2	XP_001138228.1
Homo sapiens (human)	TMIGD2	NP_653216.2
Bos taurus (cattle)	TMIGD2	XP_002688979.1

Gene Ontology
Bibliography

Related articles in PubMed

IGPR-1 Is Required for Endothelial Cell-Cell Adhesion and Barrier Function.
Wang YHW, Meyer RD, Bondzie PA, Jiang Y, Rahimi I, Rezazadeh K, Mehta M, Laver NMV, Costello CE, Rahimi N
Journal of molecular biology428(24 Pt B)5019-5033(2016 Dec)

B7-H5 costimulates human T cells via CD28H.
Zhu Y, Yao S, Iliopoulou BP, Han X, Augustine MM, Xu H, Phennicie RT, Flies SJ, Broadwater M, Ruff W, Taube JM, Zheng L, Luo L, Zhu G, Chen J, Chen L
Nature communications42043(2013)

Identification of IGPR-1 as a novel adhesion molecule involved in angiogenesis.
Rahimi N, Rezazadeh K, Mahoney JE, Hartsough E, Meyer RD
Molecular biology of the cell23(9)1646-56(2012 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The authors demonstrate that IGPR-1 is localized to endothelial adherens junctions and, through trans-homophilic dimerization, regulates endothelial cell-cell adhesion and barrier function.
Title: IGPR-1 Is Required for Endothelial Cell-Cell Adhesion and Barrier Function.

B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H.
Title: B7-H5 costimulates human T cells via CD28H.

Authors identified IGPR-1, also called TMIGD2, gene as a novel cell adhesion receptor that is expressed in various human organs and tissues, mainly in cells with epithelium and endothelium origins.
Title: Identification of IGPR-1 as a novel adhesion molecule involved in angiogenesis.

The following TMIGD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMIGD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25646	NM_144615.2 Latest version!	Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu25650	NM_001169126.1 Latest version!	Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu75384	NM_001308232.1 Latest version!	Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu104623	XM_024451359.1 Latest version!	Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu88205	XM_017026284.1 Latest version!	Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMIGD2 ( NM_144615.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_653216.2 Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu25646
Clone ID Related Accession (Same CDS sequence)	NM_144615.2
Accession Version	NM_144615.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 849bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Homo sapiens(human)
Product	transmembrane and immunoglobulin domain-containing protein 2 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC015655.1, AC008616.6 and BU629751.1. On Dec 16, 2009 this sequence version replaced NM_144615.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC015655.1, SRR1163658.75244.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGTCCC CGGGCATGGT GCTGGGCCTC CTGGTGCAGA TCTGGGCCCT GCAAGAAGCC 
TCAAGCCTGA GCGTGCAGCA GGGGCCCAAC TTGCTGCAGG TGAGGCAGGG CAGTCAGGCG 
ACCCTGGTCT GCCAGGTGGA CCAGGCCACA GCCTGGGAAC GGCTCCGTGT TAAGTGGACA 
AAGGATGGGG CCATCCTGTG TCAACCGTAC ATCACCAACG GCAGCCTCAG CCTGGGGGTC 
TGCGGGCCCC AGGGACGGCT CTCCTGGCAG GCACCCAGCC ATCTCACCCT GCAGCTGGAC 
CCTGTGAGCC TCAACCACAG CGGGGCGTAC GTGTGCTGGG CGGCCGTAGA GATTCCTGAG 
TTGGAGGAGG CTGAGGGCAA CATAACAAGG CTCTTTGTGG ACCCAGATGA CCCCACACAG 
AACAGAAACC GGATCGCAAG CTTCCCAGGA TTCCTCTTCG TGCTGCTGGG GGTGGGAAGC 
ATGGGTGTGG CTGCGATCGT GTGGGGTGCC TGGTTCTGGG GCCGCCGCAG CTGCCAGCAA 
AGGGACTCAG GTAACAGCCC AGGAAATGCA TTCTACAGCA ACGTCCTATA CCGGCCCCGG 
GGGGCCCCAA AGAAGAGTGA GGACTGCTCT GGAGAGGGGA AGGACCAGAG GGGCCAGAGC 
ATTTATTCAA CCTCCTTCCC GCAACCGGCC CCCCGCCAGC CGCACCTGGC GTCAAGACCC 
TGCCCCAGCC CGAGACCCTG CCCCAGCCCC AGGCCCGGCC ACCCCGTCTC TATGGTCAGG 
GTCTCTCCTA GACCAAGCCC CACCCAGCAG CCGAGGCCAA AAGGGTTCCC CAAAGTGGGA 
GAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_653216.2
CDS	47..895
Translation	MGSPGMVLGLLVQIWALQEASSLSVQQGPNLLQVRQGSQATLVCQVDQATAWERLRVKWTKDGAILCQPYITNGSLSLGVCGPQGRLSWQAPSHLTLQLDPVSLNHSGAYVCWAAVEIPELEEAEGNITRLFVDPDDPTQNRNRIASFPGFLFVLLGVGSMGVAAIVWGAWFWGRRSCQQRDSGNSPGNAFYSNVLYRPRGAPKKSEDCSGEGKDQRGQSIYSTSFPQPAPRQPHLASRPCPSPRPCPSPRPGHPVSMVRVSPRPSPTQQPRPKGFPKVGEE

Target ORF information:

RefSeq Version	NM_144615.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144615.2

ORF Insert Sequence:

ATGGGGTCCC CGGGCATGGT GCTGGGCCTC CTGGTGCAGA TCTGGGCCCT GCAAGAAGCC 
TCAAGCCTGA GCGTGCAGCA GGGGCCCAAC TTGCTGCAGG TGAGGCAGGG CAGTCAGGCG 
ACCCTGGTCT GCCAGGTGGA CCAGGCCACA GCCTGGGAAC GGCTCCGTGT TAAGTGGACA 
AAGGATGGGG CCATCCTGTG TCAACCGTAC ATCACCAACG GCAGCCTCAG CCTGGGGGTC 
TGCGGGCCCC AGGGACGGCT CTCCTGGCAG GCACCCAGCC ATCTCACCCT GCAGCTGGAC 
CCTGTGAGCC TCAACCACAG CGGGGCGTAC GTGTGCTGGG CGGCCGTAGA GATTCCTGAG 
TTGGAGGAGG CTGAGGGCAA CATAACAAGG CTCTTTGTGG ACCCAGATGA CCCCACACAG 
AACAGAAACC GGATCGCAAG CTTCCCAGGA TTCCTCTTCG TGCTGCTGGG GGTGGGAAGC 
ATGGGTGTGG CTGCGATCGT GTGGGGTGCC TGGTTCTGGG GCCGCCGCAG CTGCCAGCAA 
AGGGACTCAG GTAACAGCCC AGGAAATGCA TTCTACAGCA ACGTCCTATA CCGGCCCCGG 
GGGGCCCCAA AGAAGAGTGA GGACTGCTCT GGAGAGGGGA AGGACCAGAG GGGCCAGAGC 
ATTTATTCAA CCTCCTTCCC GCAACCGGCC CCCCGCCAGC CGCACCTGGC GTCAAGACCC 
TGCCCCAGCC CGAGACCCTG CCCCAGCCCC AGGCCCGGCC ACCCCGTCTC TATGGTCAGG 
GTCTCTCCTA GACCAAGCCC CACCCAGCAG CCGAGGCCAA AAGGGTTCCC CAAAGTGGGA 
GAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMIGD2 ( NM_001169126.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001162597.1 Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu25650
Clone ID Related Accession (Same CDS sequence)	NM_001169126.1
Accession Version	NM_001169126.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Homo sapiens(human)
Product	transmembrane and immunoglobulin domain-containing protein 2 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC015655.1, AY358964.1 and BU629751.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY358964.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGTCCC CGGGCATGGT GCTGGGCCTC CTGGTGCAGA TCTGGGCCCT GCAAGAAGCC 
TCAAGCCTGA GCGTGCAGCA GGGGCCCAAC TTGCTGCAGG TGAGGCAGGG CAGTCAGGCG 
ACCCTGGTCT GCCAGGTGGA CCAGGCCACA GCCTGGGAAC GGCTCCGTGT TAAGTGGACA 
AAGGATGGGG CCATCCTGTG TCAACCGTAC ATCACCAACG GCAGCCTCAG CCTGGGGGTC 
TGCGGGCCCC AGGGACGGCT CTCCTGGCAG GCACCCAGCC ATCTCACCCT GCAGCTGGAC 
CCTGTGAGCC TCAACCACAG CGGGGCGTAC GTGTGCTGGG CGGCCGTAGA GATTCCTGAG 
TTGGAGGAGG CTGAGGGCAA CATAACAAGG CTCTTTGTGG ACCCAGATGA CCCCACACAG 
AACAGAAACC GGATCGCAAG CTTCCCAGGA TTCCTCTTCG TGCTGCTGGG GGTGGGAAGC 
ATGGGTGTGG CTGCGATCGT GTGGGGTGCC TGGTTCTGGG GCCGCCGCAG CTGCCAGCAA 
AGGGACTCAG GAAATGCATT CTACAGCAAC GTCCTATACC GGCCCCGGGG GGCCCCAAAG 
AAGAGTGAGG ACTGCTCTGG AGAGGGGAAG GACCAGAGGG GCCAGAGCAT TTATTCAACC 
TCCTTCCCGC AACCGGCCCC CCGCCAGCCG CACCTGGCGT CAAGACCCTG CCCCAGCCCG 
AGACCCTGCC CCAGCCCCAG GCCCGGCCAC CCCGTCTCTA TGGTCAGGGT CTCTCCTAGA 
CCAAGCCCCA CCCAGCAGCC GAGGCCAAAA GGGTTCCCCA AAGTGGGAGA GGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001162597.1
CDS	47..883
Translation	MGSPGMVLGLLVQIWALQEASSLSVQQGPNLLQVRQGSQATLVCQVDQATAWERLRVKWTKDGAILCQPYITNGSLSLGVCGPQGRLSWQAPSHLTLQLDPVSLNHSGAYVCWAAVEIPELEEAEGNITRLFVDPDDPTQNRNRIASFPGFLFVLLGVGSMGVAAIVWGAWFWGRRSCQQRDSGNAFYSNVLYRPRGAPKKSEDCSGEGKDQRGQSIYSTSFPQPAPRQPHLASRPCPSPRPCPSPRPGHPVSMVRVSPRPSPTQQPRPKGFPKVGEE

Target ORF information:

RefSeq Version	NM_001169126.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001169126.1

ORF Insert Sequence:

ATGGGGTCCC CGGGCATGGT GCTGGGCCTC CTGGTGCAGA TCTGGGCCCT GCAAGAAGCC 
TCAAGCCTGA GCGTGCAGCA GGGGCCCAAC TTGCTGCAGG TGAGGCAGGG CAGTCAGGCG 
ACCCTGGTCT GCCAGGTGGA CCAGGCCACA GCCTGGGAAC GGCTCCGTGT TAAGTGGACA 
AAGGATGGGG CCATCCTGTG TCAACCGTAC ATCACCAACG GCAGCCTCAG CCTGGGGGTC 
TGCGGGCCCC AGGGACGGCT CTCCTGGCAG GCACCCAGCC ATCTCACCCT GCAGCTGGAC 
CCTGTGAGCC TCAACCACAG CGGGGCGTAC GTGTGCTGGG CGGCCGTAGA GATTCCTGAG 
TTGGAGGAGG CTGAGGGCAA CATAACAAGG CTCTTTGTGG ACCCAGATGA CCCCACACAG 
AACAGAAACC GGATCGCAAG CTTCCCAGGA TTCCTCTTCG TGCTGCTGGG GGTGGGAAGC 
ATGGGTGTGG CTGCGATCGT GTGGGGTGCC TGGTTCTGGG GCCGCCGCAG CTGCCAGCAA 
AGGGACTCAG GAAATGCATT CTACAGCAAC GTCCTATACC GGCCCCGGGG GGCCCCAAAG 
AAGAGTGAGG ACTGCTCTGG AGAGGGGAAG GACCAGAGGG GCCAGAGCAT TTATTCAACC 
TCCTTCCCGC AACCGGCCCC CCGCCAGCCG CACCTGGCGT CAAGACCCTG CCCCAGCCCG 
AGACCCTGCC CCAGCCCCAG GCCCGGCCAC CCCGTCTCTA TGGTCAGGGT CTCTCCTAGA 
CCAAGCCCCA CCCAGCAGCC GAGGCCAAAA GGGTTCCCCA AAGTGGGAGA GGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMIGD2 ( NM_001308232.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001295161.1 Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu75384
Clone ID Related Accession (Same CDS sequence)	NM_001308232.1
Accession Version	NM_001308232.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Homo sapiens(human)
Product	transmembrane and immunoglobulin domain-containing protein 2 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC015655.1, HQ452865.1, AY358964.1 and HY260382.1. On Apr 28, 2015 this sequence version replaced XM_011527679.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 3, which is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: HQ452865.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2146236 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGTCCC CGGGCATGGT GCTGGGCCTC CTGGTGCAGA TCTGGGATGA CCCCACACAG 
AACAGAAACC GGATCGCAAG CTTCCCAGGA TTCCTCTTCG TGCTGCTGGG GGTGGGAAGC 
ATGGGTGTGG CTGCGATCGT GTGGGGTGCC TGGTTCTGGG GCCGCCGCAG CTGCCAGCAA 
AGGGACTCAG GTAACAGCCC AGGAAATGCA TTCTACAGCA ACGTCCTATA CCGGCCCCGG 
GGGGCCCCAA AGAAGAGTGA GGACTGCTCT GGAGAGGGGA AGGACCAGAG GGGCCAGAGC 
ATTTATTCAA CCTCCTTCCC GCAACCGGCC CCCCGCCAGC CGCACCTGGC GTCAAGACCC 
TGCCCCAGCC CGAGACCCTG CCCCAGCCCC AGGCCCGGCC ACCCCGTCTC TATGGTCAGG 
GTCTCTCCTA GACCAAGCCC CACCCAGCAG CCGAGGCCAA AAGGGTTCCC CAAAGTGGGA 
GAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295161.1
CDS	47..535
Translation	MGSPGMVLGLLVQIWDDPTQNRNRIASFPGFLFVLLGVGSMGVAAIVWGAWFWGRRSCQQRDSGNSPGNAFYSNVLYRPRGAPKKSEDCSGEGKDQRGQSIYSTSFPQPAPRQPHLASRPCPSPRPCPSPRPGHPVSMVRVSPRPSPTQQPRPKGFPKVGEE

Target ORF information:

RefSeq Version	NM_001308232.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001308232.1

ORF Insert Sequence:

ATGGGGTCCC CGGGCATGGT GCTGGGCCTC CTGGTGCAGA TCTGGGATGA CCCCACACAG 
AACAGAAACC GGATCGCAAG CTTCCCAGGA TTCCTCTTCG TGCTGCTGGG GGTGGGAAGC 
ATGGGTGTGG CTGCGATCGT GTGGGGTGCC TGGTTCTGGG GCCGCCGCAG CTGCCAGCAA 
AGGGACTCAG GTAACAGCCC AGGAAATGCA TTCTACAGCA ACGTCCTATA CCGGCCCCGG 
GGGGCCCCAA AGAAGAGTGA GGACTGCTCT GGAGAGGGGA AGGACCAGAG GGGCCAGAGC 
ATTTATTCAA CCTCCTTCCC GCAACCGGCC CCCCGCCAGC CGCACCTGGC GTCAAGACCC 
TGCCCCAGCC CGAGACCCTG CCCCAGCCCC AGGCCCGGCC ACCCCGTCTC TATGGTCAGG 
GTCTCTCCTA GACCAAGCCC CACCCAGCAG CCGAGGCCAA AAGGGTTCCC CAAAGTGGGA 
GAGGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMIGD2 ( XM_024451359.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307127.1 Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu104623
Clone ID Related Accession (Same CDS sequence)	XM_024451359.1
Accession Version	XM_024451359.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 585bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane and immunoglobulin domain-containing protein 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGTCCC CGGGCATGGT GCTGGGCCTC CTGGTGCAGA TCTGGGCCCT GCAAGAAGCC 
TCAAGCCTGA GCGTGCAGCA GGGGCCCAAC TTGCTGCAGG TGAGGCAGGG CAGTCAGGCG 
ACCCTGGTCT GCCAGGTGGA CCAGGCCACA GCCTGGGAAC GGCTCCGTGT TAAGTGGACA 
AAGGATGGGG CCATCCTGTG TCAACCGTAC ATCACCAACG GCAGCCTCAG CCTGGGGGTC 
TGCGGGCCCC AGGGACGGCT CTCCTGGCAG GCACCCAGCC ATCTCACCCT GCAGCTGGAC 
CCTGTGAGCC TCAACCACAG CGGGGCGTAC GTGTGCTGGG CGGCCGTAGA GATTCCTGAG 
TTGGAGGAGG CTGAGGGCAA CATAACAAGG CTCTTTGTGG ACCCAGATGA CCCCACACAG 
AACAGAAACC GGATCGCAAG CTTCCCAGGA TTCCTCTTCG TGCTGCTGGG GGTGGGAAGC 
ATGGGTGTGG CTGCGATCGT GTGGGGTGCC TGGTTCTGGG GCCGCCGCAG CTGCCAGCAA 
AGGGACTCAG AAATAGAGAC AAAGCCCCTA GCCTGTGCAA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307127.1
CDS	55..639
Translation	MGSPGMVLGLLVQIWALQEASSLSVQQGPNLLQVRQGSQATLVCQVDQATAWERLRVKWTKDGAILCQPYITNGSLSLGVCGPQGRLSWQAPSHLTLQLDPVSLNHSGAYVCWAAVEIPELEEAEGNITRLFVDPDDPTQNRNRIASFPGFLFVLLGVGSMGVAAIVWGAWFWGRRSCQQRDSEIETKPLACAT

Target ORF information:

RefSeq Version	XM_024451359.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451359.1

ORF Insert Sequence:

ATGGGGTCCC CGGGCATGGT GCTGGGCCTC CTGGTGCAGA TCTGGGCCCT GCAAGAAGCC 
TCAAGCCTGA GCGTGCAGCA GGGGCCCAAC TTGCTGCAGG TGAGGCAGGG CAGTCAGGCG 
ACCCTGGTCT GCCAGGTGGA CCAGGCCACA GCCTGGGAAC GGCTCCGTGT TAAGTGGACA 
AAGGATGGGG CCATCCTGTG TCAACCGTAC ATCACCAACG GCAGCCTCAG CCTGGGGGTC 
TGCGGGCCCC AGGGACGGCT CTCCTGGCAG GCACCCAGCC ATCTCACCCT GCAGCTGGAC 
CCTGTGAGCC TCAACCACAG CGGGGCGTAC GTGTGCTGGG CGGCCGTAGA GATTCCTGAG 
TTGGAGGAGG CTGAGGGCAA CATAACAAGG CTCTTTGTGG ACCCAGATGA CCCCACACAG 
AACAGAAACC GGATCGCAAG CTTCCCAGGA TTCCTCTTCG TGCTGCTGGG GGTGGGAAGC 
ATGGGTGTGG CTGCGATCGT GTGGGGTGCC TGGTTCTGGG GCCGCCGCAG CTGCCAGCAA 
AGGGACTCAG AAATAGAGAC AAAGCCCCTA GCCTGTGCAA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMIGD2 ( XM_017026284.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016881773.1 Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu88205
Clone ID Related Accession (Same CDS sequence)	XM_017026284.1
Accession Version	XM_017026284.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane and immunoglobulin domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGTCCC CGGGCATGGT GCTGGGCCTC CTGGTGCAGA TCTGGGCCCT GCAAGAAGCC 
TCAAGCCTGA GCGTGCAGCA GGGGCCCAAC TTGCTGCAGG TGAGGCAGGG CAGTCAGGCG 
ACCCTGGTCT GCCAGGTGGA CCAGGCCACA GCCTGGGAAC GGCTCCGTGT TAAGTGGACA 
AAGGATGGGG CCATCCTGTG TCAACCGTAC ATCACCAACG GCAGCCTCAG CCTGGGGGTC 
TGCGGGCCCC AGGGACGGCT CTCCTGGCAG GCACCCAGCC ATCTCACCCT GCAGCTGGAC 
CCTGTGAGCC TCAACCACAG CGGGGCGTAC GTGTGCTGGG CGGCCGTAGA GATTCCTGAG 
TTGGAGGAGG CTGAGGGCAA CATAACAAGG CTCTTTGTGG ACCCAGATGA CCCCACACAG 
AACAGAAACC GGATCGCAAG CTTCCCAGGA TTCCTCTTCG TGCTGCTGGG GGTGGGAAGC 
ATGGGTGTGG CTGCGATCGT GTGGGGTGCC TGGTTCTGGG GCCGCCGCAG CTGCCAGCAA 
AGGGACTCAG GTAACAGCCC AGAAATAGAG ACAAAGCCCC TAGCCTGTGC AACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016881773.1
CDS	55..651
Translation	MGSPGMVLGLLVQIWALQEASSLSVQQGPNLLQVRQGSQATLVCQVDQATAWERLRVKWTKDGAILCQPYITNGSLSLGVCGPQGRLSWQAPSHLTLQLDPVSLNHSGAYVCWAAVEIPELEEAEGNITRLFVDPDDPTQNRNRIASFPGFLFVLLGVGSMGVAAIVWGAWFWGRRSCQQRDSGNSPEIETKPLACAT

Target ORF information:

RefSeq Version	XM_017026284.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane and immunoglobulin domain containing 2 (TMIGD2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026284.1

ORF Insert Sequence:

ATGGGGTCCC CGGGCATGGT GCTGGGCCTC CTGGTGCAGA TCTGGGCCCT GCAAGAAGCC 
TCAAGCCTGA GCGTGCAGCA GGGGCCCAAC TTGCTGCAGG TGAGGCAGGG CAGTCAGGCG 
ACCCTGGTCT GCCAGGTGGA CCAGGCCACA GCCTGGGAAC GGCTCCGTGT TAAGTGGACA 
AAGGATGGGG CCATCCTGTG TCAACCGTAC ATCACCAACG GCAGCCTCAG CCTGGGGGTC 
TGCGGGCCCC AGGGACGGCT CTCCTGGCAG GCACCCAGCC ATCTCACCCT GCAGCTGGAC 
CCTGTGAGCC TCAACCACAG CGGGGCGTAC GTGTGCTGGG CGGCCGTAGA GATTCCTGAG 
TTGGAGGAGG CTGAGGGCAA CATAACAAGG CTCTTTGTGG ACCCAGATGA CCCCACACAG 
AACAGAAACC GGATCGCAAG CTTCCCAGGA TTCCTCTTCG TGCTGCTGGG GGTGGGAAGC 
ATGGGTGTGG CTGCGATCGT GTGGGGTGCC TGGTTCTGGG GCCGCCGCAG CTGCCAGCAA 
AGGGACTCAG GTAACAGCCC AGAAATAGAG ACAAAGCCCC TAGCCTGTGC AACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

IGPR-1 Is Required for Endothelial Cell-Cell Adhesion and Barrier Function.
Journal of molecular biology428(24 Pt B)5019-5033(2016 Dec)
Wang YHW,Meyer RD,Bondzie PA,Jiang Y,Rahimi I,Rezazadeh K,Mehta M,Laver NMV,Costello CE,Rahimi N

B7-H5 costimulates human T cells via CD28H.
Nature communications42043(2013)
Zhu Y,Yao S,Iliopoulou BP,Han X,Augustine MM,Xu H,Phennicie RT,Flies SJ,Broadwater M,Ruff W,Taube JM,Zheng L,Luo L,Zhu G,Chen J,Chen L

Identification of IGPR-1 as a novel adhesion molecule involved in angiogenesis.
Molecular biology of the cell23(9)1646-56(2012 May)
Rahimi N,Rezazadeh K,Mahoney JE,Hartsough E,Meyer RD

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TMIGD2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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