VASN cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	VASN
Entrez Gene ID	114990
Full Name	vasorin
Synonyms	SLITL2
General protein information	Preferred Names vasorin Names vasorin protein slit-like 2 slit-like 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p13.3
Disorder MIM:	608843

mRNA and Protein(s)

mRNA	Protein	Name
NM_138440.2	NP_612449.2	vasorin precursor
NM_138440.3	NP_612449.2	vasorin precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	VASN	XP_003315004.1
Bos taurus (cattle)	VASN	NP_001077265.1
Mus musculus (house mouse)	Vasn	NP_647468.2
Gallus gallus (chicken)	VASN	XP_004945448.1
Danio rerio (zebrafish)	LOC100535884	XP_005174101.1
Canis lupus familiaris (dog)	VASN	XP_003434911.1
Danio rerio (zebrafish)	vasnb	NP_001104232.1
Xenopus tropicalis (tropical clawed frog)	vasn	NP_001005036.1
Danio rerio (zebrafish)	vasna	NP_001018141.1
Homo sapiens (human)	VASN	NP_612449.2
Rattus norvegicus (Norway rat)	Vasn	NP_001102852.1

Gene Ontology
Bibliography

Related articles in PubMed

Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells.
Man J, Yu X, Huang H, Zhou W, Xiang C, Huang H, Miele L, Liu Z, Bebek G, Bao S, Yu JS
Cell stem cell22(1)104-118.e6(2018 Jan)

Exosomal transfer of vasorin expressed in hepatocellular carcinoma cells promotes migration of human umbilical vein endothelial cells.
Huang A, Dong J, Li S, Wang C, Ding H, Li H, Su X, Ge X, Sun L, Bai C, Shen X, Fang T, Li J, Shao N
International journal of biological sciences11(8)961-9(2015)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

confirmed for the first time that HepG2-derived VASN can be transferred to human umbilical vein endothelial cells (HUVECs) via receptor mediated endocytosis of exosomes, at least in part through HSPGs
Title: Exosomal transfer of vasorin expressed in hepatocellular carcinoma cells promotes migration of human umbilical vein endothelial cells.

results suggest that down-regulation of vasorin expression contributes to neointimal formation after vascular injury and that vasorin modulates cellular responses to pathological stimuli in the vessel wall [vasorin]
Title: Vasorin, a transforming growth factor beta-binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo.

The following VASN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VASN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06115	NM_138440.3 Latest version!	Homo sapiens vasorin (VASN), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu06115	NM_138440.2	Homo sapiens vasorin (VASN), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

VASN ( NM_138440.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_612449.2 Homo sapiens vasorin (VASN), mRNA.

Price & Availability↑

CloneID	OHu06115
Clone ID Related Accession (Same CDS sequence)	NM_138440.2 , NM_138440.3
Accession Version	NM_138440.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2022bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	vasorin precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC068575.1 and BC013767.1. On Feb 23, 2006 this sequence version replaced NM_138440.1. ##Evidence-Data-START## Transcript exon combination :: BC068575.1, AY358299.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END##

ATGTGCTCCA GGGTCCCTCT GCTGCTGCCG CTGCTCCTGC TACTGGCCCT GGGGCCTGGG 
GTGCAGGGCT GCCCATCCGG CTGCCAGTGC AGCCAGCCAC AGACAGTCTT CTGCACTGCC 
CGCCAGGGGA CCACGGTGCC CCGAGACGTG CCACCCGACA CGGTGGGGCT GTACGTCTTT 
GAGAACGGCA TCACCATGCT CGACGCAGGC AGCTTTGCCG GCCTGCCGGG CCTGCAGCTC 
CTGGACCTGT CACAGAACCA GATCGCCAGC CTGCCCAGCG GGGTCTTCCA GCCACTCGCC 
AACCTCAGCA ACCTGGACCT GACAGCCAAC AGGCTGCATG AAATCACCAA TGAGACCTTC 
CGTGGCCTGC GGCGCCTCGA GCGCCTCTAC CTGGGCAAGA ACCGCATCCG CCACATCCAG 
CCTGGTGCCT TCGACACGCT CGACCGCCTC CTGGAGCTCA AGCTGCAGGA CAACGAGCTG 
CGGGCACTGC CCCCGCTGCG CCTGCCCCGC CTGCTGCTGC TGGACCTCAG CCACAACAGC 
CTCCTGGCCC TGGAGCCCGG CATCCTGGAC ACTGCCAACG TGGAGGCGCT GCGGCTGGCT 
GGTCTGGGGC TGCAGCAGCT GGACGAGGGG CTCTTCAGCC GCTTGCGCAA CCTCCACGAC 
CTGGATGTGT CCGACAACCA GCTGGAGCGA GTGCCACCTG TGATCCGAGG CCTCCGGGGC 
CTGACGCGCC TGCGGCTGGC CGGCAACACC CGCATTGCCC AGCTGCGGCC CGAGGACCTG 
GCCGGCCTGG CTGCCCTGCA GGAGCTGGAT GTGAGCAACC TAAGCCTGCA GGCCCTGCCT 
GGCGACCTCT CGGGCCTCTT CCCCCGCCTG CGGCTGCTGG CAGCTGCCCG CAACCCCTTC 
AACTGCGTGT GCCCCCTGAG CTGGTTTGGC CCCTGGGTGC GCGAGAGCCA CGTCACACTG 
GCCAGCCCTG AGGAGACGCG CTGCCACTTC CCGCCCAAGA ACGCTGGCCG GCTGCTCCTG 
GAGCTTGACT ACGCCGACTT TGGCTGCCCA GCCACCACCA CCACAGCCAC AGTGCCCACC 
ACGAGGCCCG TGGTGCGGGA GCCCACAGCC TTGTCTTCTA GCTTGGCTCC TACCTGGCTT 
AGCCCCACAG AGCCGGCCAC TGAGGCCCCC AGCCCGCCCT CCACTGCCCC ACCGACTGTA 
GGGCCTGTCC CCCAGCCCCA GGACTGCCCA CCGTCCACCT GCCTCAATGG GGGCACATGC 
CACCTGGGGA CACGGCACCA CCTGGCGTGC TTGTGCCCCG AAGGCTTCAC GGGCCTGTAC 
TGTGAGAGCC AGATGGGGCA GGGGACACGG CCCAGCCCTA CACCAGTCAC GCCGAGGCCA 
CCACGGTCCC TGACCCTGGG CATCGAGCCG GTGAGCCCCA CCTCCCTGCG CGTGGGGCTG 
CAGCGCTACC TCCAGGGGAG CTCCGTGCAG CTCAGGAGCC TCCGTCTCAC CTATCGCAAC 
CTATCGGGCC CTGATAAGCG GCTGGTGACG CTGCGACTGC CTGCCTCGCT CGCTGAGTAC 
ACGGTCACCC AGCTGCGGCC CAACGCCACT TACTCCGTCT GTGTCATGCC TTTGGGGCCC 
GGGCGGGTGC CGGAGGGCGA GGAGGCCTGC GGGGAGGCCC ATACACCCCC AGCCGTCCAC 
TCCAACCACG CCCCAGTCAC CCAGGCCCGC GAGGGCAACC TGCCGCTCCT CATTGCGCCC 
GCCCTGGCCG CGGTGCTCCT GGCCGCGCTG GCTGCGGTGG GGGCAGCCTA CTGTGTGCGG 
CGGGGGCGGG CCATGGCAGC AGCGGCTCAG GACAAAGGGC AGGTGGGGCC AGGGGCTGGG 
CCCCTGGAAC TGGAGGGAGT GAAGGTCCCC TTGGAGCCAG GCCCGAAGGC AACAGAGGGC 
GGTGGAGAGG CCCTGCCCAG CGGGTCTGAG TGTGAGGTGC CACTCATGGG CTTCCCAGGG 
CCTGGCCTCC AGTCACCCCT CCACGCAAAG CCCTACATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612449.2
CDS	156..2177
Translation	MCSRVPLLLPLLLLLALGPGVQGCPSGCQCSQPQTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCVCPLSWFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPATTTTATVPTTRPVVREPTALSSSLAPTWLSPTEPATEAPSPPSTAPPTVGPVPQPQDCPPSTCLNGGTCHLGTRHHLACLCPEGFTGLYCESQMGQGTRPSPTPVTPRPPRSLTLGIEPVSPTSLRVGLQRYLQGSSVQLRSLRLTYRNLSGPDKRLVTLRLPASLAEYTVTQLRPNATYSVCVMPLGPGRVPEGEEACGEAHTPPAVHSNHAPVTQAREGNLPLLIAPALAAVLLAALAAVGAAYCVRRGRAMAAAAQDKGQVGPGAGPLELEGVKVPLEPGPKATEGGGEALPSGSECEVPLMGFPGPGLQSPLHAKPYI

Target ORF information:

RefSeq Version	NM_138440.2
Organism	Homo sapiens(human)
Definition	Homo sapiens vasorin (VASN), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138440.2

ORF Insert Sequence:

ATGTGCTCCA GGGTCCCTCT GCTGCTGCCG CTGCTCCTGC TACTGGCCCT GGGGCCTGGG 
GTGCAGGGCT GCCCATCCGG CTGCCAGTGC AGCCAGCCAC AGACAGTCTT CTGCACTGCC 
CGCCAGGGGA CCACGGTGCC CCGAGACGTG CCACCCGACA CGGTGGGGCT GTACGTCTTT 
GAGAACGGCA TCACCATGCT CGACGCAGGC AGCTTTGCCG GCCTGCCGGG CCTGCAGCTC 
CTGGACCTGT CACAGAACCA GATCGCCAGC CTGCCCAGCG GGGTCTTCCA GCCACTCGCC 
AACCTCAGCA ACCTGGACCT GACAGCCAAC AGGCTGCATG AAATCACCAA TGAGACCTTC 
CGTGGCCTGC GGCGCCTCGA GCGCCTCTAC CTGGGCAAGA ACCGCATCCG CCACATCCAG 
CCTGGTGCCT TCGACACGCT CGACCGCCTC CTGGAGCTCA AGCTGCAGGA CAACGAGCTG 
CGGGCACTGC CCCCGCTGCG CCTGCCCCGC CTGCTGCTGC TGGACCTCAG CCACAACAGC 
CTCCTGGCCC TGGAGCCCGG CATCCTGGAC ACTGCCAACG TGGAGGCGCT GCGGCTGGCT 
GGTCTGGGGC TGCAGCAGCT GGACGAGGGG CTCTTCAGCC GCTTGCGCAA CCTCCACGAC 
CTGGATGTGT CCGACAACCA GCTGGAGCGA GTGCCACCTG TGATCCGAGG CCTCCGGGGC 
CTGACGCGCC TGCGGCTGGC CGGCAACACC CGCATTGCCC AGCTGCGGCC CGAGGACCTG 
GCCGGCCTGG CTGCCCTGCA GGAGCTGGAT GTGAGCAACC TAAGCCTGCA GGCCCTGCCT 
GGCGACCTCT CGGGCCTCTT CCCCCGCCTG CGGCTGCTGG CAGCTGCCCG CAACCCCTTC 
AACTGCGTGT GCCCCCTGAG CTGGTTTGGC CCCTGGGTGC GCGAGAGCCA CGTCACACTG 
GCCAGCCCTG AGGAGACGCG CTGCCACTTC CCGCCCAAGA ACGCTGGCCG GCTGCTCCTG 
GAGCTTGACT ACGCCGACTT TGGCTGCCCA GCCACCACCA CCACAGCCAC AGTGCCCACC 
ACGAGGCCCG TGGTGCGGGA GCCCACAGCC TTGTCTTCTA GCTTGGCTCC TACCTGGCTT 
AGCCCCACAG AGCCGGCCAC TGAGGCCCCC AGCCCGCCCT CCACTGCCCC ACCGACTGTA 
GGGCCTGTCC CCCAGCCCCA GGACTGCCCA CCGTCCACCT GCCTCAATGG GGGCACATGC 
CACCTGGGGA CACGGCACCA CCTGGCGTGC TTGTGCCCCG AAGGCTTCAC GGGCCTGTAC 
TGTGAGAGCC AGATGGGGCA GGGGACACGG CCCAGCCCTA CACCAGTCAC GCCGAGGCCA 
CCACGGTCCC TGACCCTGGG CATCGAGCCG GTGAGCCCCA CCTCCCTGCG CGTGGGGCTG 
CAGCGCTACC TCCAGGGGAG CTCCGTGCAG CTCAGGAGCC TCCGTCTCAC CTATCGCAAC 
CTATCGGGCC CTGATAAGCG GCTGGTGACG CTGCGACTGC CTGCCTCGCT CGCTGAGTAC 
ACGGTCACCC AGCTGCGGCC CAACGCCACT TACTCCGTCT GTGTCATGCC TTTGGGGCCC 
GGGCGGGTGC CGGAGGGCGA GGAGGCCTGC GGGGAGGCCC ATACACCCCC AGCCGTCCAC 
TCCAACCACG CCCCAGTCAC CCAGGCCCGC GAGGGCAACC TGCCGCTCCT CATTGCGCCC 
GCCCTGGCCG CGGTGCTCCT GGCCGCGCTG GCTGCGGTGG GGGCAGCCTA CTGTGTGCGG 
CGGGGGCGGG CCATGGCAGC AGCGGCTCAG GACAAAGGGC AGGTGGGGCC AGGGGCTGGG 
CCCCTGGAAC TGGAGGGAGT GAAGGTCCCC TTGGAGCCAG GCCCGAAGGC AACAGAGGGC 
GGTGGAGAGG CCCTGCCCAG CGGGTCTGAG TGTGAGGTGC CACTCATGGG CTTCCCAGGG 
CCTGGCCTCC AGTCACCCCT CCACGCAAAG CCCTACATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VASN ( NM_138440.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_612449.2 Homo sapiens vasorin (VASN), mRNA.

Price & Availability↑

CloneID	OHu06115
Clone ID Related Accession (Same CDS sequence)	NM_138440.2 , NM_138440.3
Accession Version	NM_138440.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2022bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-20
Organism	Homo sapiens(human)
Product	vasorin precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC068575.1, BC013767.1 and AC012676.5. On Nov 23, 2018 this sequence version replaced NM_138440.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC068575.1, AY358299.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000304735.4/ ENSP00000306864.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTGCTCCA GGGTCCCTCT GCTGCTGCCG CTGCTCCTGC TACTGGCCCT GGGGCCTGGG 
GTGCAGGGCT GCCCATCCGG CTGCCAGTGC AGCCAGCCAC AGACAGTCTT CTGCACTGCC 
CGCCAGGGGA CCACGGTGCC CCGAGACGTG CCACCCGACA CGGTGGGGCT GTACGTCTTT 
GAGAACGGCA TCACCATGCT CGACGCAGGC AGCTTTGCCG GCCTGCCGGG CCTGCAGCTC 
CTGGACCTGT CACAGAACCA GATCGCCAGC CTGCCCAGCG GGGTCTTCCA GCCACTCGCC 
AACCTCAGCA ACCTGGACCT GACAGCCAAC AGGCTGCATG AAATCACCAA TGAGACCTTC 
CGTGGCCTGC GGCGCCTCGA GCGCCTCTAC CTGGGCAAGA ACCGCATCCG CCACATCCAG 
CCTGGTGCCT TCGACACGCT CGACCGCCTC CTGGAGCTCA AGCTGCAGGA CAACGAGCTG 
CGGGCACTGC CCCCGCTGCG CCTGCCCCGC CTGCTGCTGC TGGACCTCAG CCACAACAGC 
CTCCTGGCCC TGGAGCCCGG CATCCTGGAC ACTGCCAACG TGGAGGCGCT GCGGCTGGCT 
GGTCTGGGGC TGCAGCAGCT GGACGAGGGG CTCTTCAGCC GCTTGCGCAA CCTCCACGAC 
CTGGATGTGT CCGACAACCA GCTGGAGCGA GTGCCACCTG TGATCCGAGG CCTCCGGGGC 
CTGACGCGCC TGCGGCTGGC CGGCAACACC CGCATTGCCC AGCTGCGGCC CGAGGACCTG 
GCCGGCCTGG CTGCCCTGCA GGAGCTGGAT GTGAGCAACC TAAGCCTGCA GGCCCTGCCT 
GGCGACCTCT CGGGCCTCTT CCCCCGCCTG CGGCTGCTGG CAGCTGCCCG CAACCCCTTC 
AACTGCGTGT GCCCCCTGAG CTGGTTTGGC CCCTGGGTGC GCGAGAGCCA CGTCACACTG 
GCCAGCCCTG AGGAGACGCG CTGCCACTTC CCGCCCAAGA ACGCTGGCCG GCTGCTCCTG 
GAGCTTGACT ACGCCGACTT TGGCTGCCCA GCCACCACCA CCACAGCCAC AGTGCCCACC 
ACGAGGCCCG TGGTGCGGGA GCCCACAGCC TTGTCTTCTA GCTTGGCTCC TACCTGGCTT 
AGCCCCACAG AGCCGGCCAC TGAGGCCCCC AGCCCGCCCT CCACTGCCCC ACCGACTGTA 
GGGCCTGTCC CCCAGCCCCA GGACTGCCCA CCGTCCACCT GCCTCAATGG GGGCACATGC 
CACCTGGGGA CACGGCACCA CCTGGCGTGC TTGTGCCCCG AAGGCTTCAC GGGCCTGTAC 
TGTGAGAGCC AGATGGGGCA GGGGACACGG CCCAGCCCTA CACCAGTCAC GCCGAGGCCA 
CCACGGTCCC TGACCCTGGG CATCGAGCCG GTGAGCCCCA CCTCCCTGCG CGTGGGGCTG 
CAGCGCTACC TCCAGGGGAG CTCCGTGCAG CTCAGGAGCC TCCGTCTCAC CTATCGCAAC 
CTATCGGGCC CTGATAAGCG GCTGGTGACG CTGCGACTGC CTGCCTCGCT CGCTGAGTAC 
ACGGTCACCC AGCTGCGGCC CAACGCCACT TACTCCGTCT GTGTCATGCC TTTGGGGCCC 
GGGCGGGTGC CGGAGGGCGA GGAGGCCTGC GGGGAGGCCC ATACACCCCC AGCCGTCCAC 
TCCAACCACG CCCCAGTCAC CCAGGCCCGC GAGGGCAACC TGCCGCTCCT CATTGCGCCC 
GCCCTGGCCG CGGTGCTCCT GGCCGCGCTG GCTGCGGTGG GGGCAGCCTA CTGTGTGCGG 
CGGGGGCGGG CCATGGCAGC AGCGGCTCAG GACAAAGGGC AGGTGGGGCC AGGGGCTGGG 
CCCCTGGAAC TGGAGGGAGT GAAGGTCCCC TTGGAGCCAG GCCCGAAGGC AACAGAGGGC 
GGTGGAGAGG CCCTGCCCAG CGGGTCTGAG TGTGAGGTGC CACTCATGGG CTTCCCAGGG 
CCTGGCCTCC AGTCACCCCT CCACGCAAAG CCCTACATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612449.2
CDS	156..2177
Translation	MCSRVPLLLPLLLLLALGPGVQGCPSGCQCSQPQTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCVCPLSWFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPATTTTATVPTTRPVVREPTALSSSLAPTWLSPTEPATEAPSPPSTAPPTVGPVPQPQDCPPSTCLNGGTCHLGTRHHLACLCPEGFTGLYCESQMGQGTRPSPTPVTPRPPRSLTLGIEPVSPTSLRVGLQRYLQGSSVQLRSLRLTYRNLSGPDKRLVTLRLPASLAEYTVTQLRPNATYSVCVMPLGPGRVPEGEEACGEAHTPPAVHSNHAPVTQAREGNLPLLIAPALAAVLLAALAAVGAAYCVRRGRAMAAAAQDKGQVGPGAGPLELEGVKVPLEPGPKATEGGGEALPSGSECEVPLMGFPGPGLQSPLHAKPYI

Target ORF information:

RefSeq Version	NM_138440.3
Organism	Homo sapiens(human)
Definition	Homo sapiens vasorin (VASN), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138440.3

ORF Insert Sequence:

ATGTGCTCCA GGGTCCCTCT GCTGCTGCCG CTGCTCCTGC TACTGGCCCT GGGGCCTGGG 
GTGCAGGGCT GCCCATCCGG CTGCCAGTGC AGCCAGCCAC AGACAGTCTT CTGCACTGCC 
CGCCAGGGGA CCACGGTGCC CCGAGACGTG CCACCCGACA CGGTGGGGCT GTACGTCTTT 
GAGAACGGCA TCACCATGCT CGACGCAGGC AGCTTTGCCG GCCTGCCGGG CCTGCAGCTC 
CTGGACCTGT CACAGAACCA GATCGCCAGC CTGCCCAGCG GGGTCTTCCA GCCACTCGCC 
AACCTCAGCA ACCTGGACCT GACAGCCAAC AGGCTGCATG AAATCACCAA TGAGACCTTC 
CGTGGCCTGC GGCGCCTCGA GCGCCTCTAC CTGGGCAAGA ACCGCATCCG CCACATCCAG 
CCTGGTGCCT TCGACACGCT CGACCGCCTC CTGGAGCTCA AGCTGCAGGA CAACGAGCTG 
CGGGCACTGC CCCCGCTGCG CCTGCCCCGC CTGCTGCTGC TGGACCTCAG CCACAACAGC 
CTCCTGGCCC TGGAGCCCGG CATCCTGGAC ACTGCCAACG TGGAGGCGCT GCGGCTGGCT 
GGTCTGGGGC TGCAGCAGCT GGACGAGGGG CTCTTCAGCC GCTTGCGCAA CCTCCACGAC 
CTGGATGTGT CCGACAACCA GCTGGAGCGA GTGCCACCTG TGATCCGAGG CCTCCGGGGC 
CTGACGCGCC TGCGGCTGGC CGGCAACACC CGCATTGCCC AGCTGCGGCC CGAGGACCTG 
GCCGGCCTGG CTGCCCTGCA GGAGCTGGAT GTGAGCAACC TAAGCCTGCA GGCCCTGCCT 
GGCGACCTCT CGGGCCTCTT CCCCCGCCTG CGGCTGCTGG CAGCTGCCCG CAACCCCTTC 
AACTGCGTGT GCCCCCTGAG CTGGTTTGGC CCCTGGGTGC GCGAGAGCCA CGTCACACTG 
GCCAGCCCTG AGGAGACGCG CTGCCACTTC CCGCCCAAGA ACGCTGGCCG GCTGCTCCTG 
GAGCTTGACT ACGCCGACTT TGGCTGCCCA GCCACCACCA CCACAGCCAC AGTGCCCACC 
ACGAGGCCCG TGGTGCGGGA GCCCACAGCC TTGTCTTCTA GCTTGGCTCC TACCTGGCTT 
AGCCCCACAG AGCCGGCCAC TGAGGCCCCC AGCCCGCCCT CCACTGCCCC ACCGACTGTA 
GGGCCTGTCC CCCAGCCCCA GGACTGCCCA CCGTCCACCT GCCTCAATGG GGGCACATGC 
CACCTGGGGA CACGGCACCA CCTGGCGTGC TTGTGCCCCG AAGGCTTCAC GGGCCTGTAC 
TGTGAGAGCC AGATGGGGCA GGGGACACGG CCCAGCCCTA CACCAGTCAC GCCGAGGCCA 
CCACGGTCCC TGACCCTGGG CATCGAGCCG GTGAGCCCCA CCTCCCTGCG CGTGGGGCTG 
CAGCGCTACC TCCAGGGGAG CTCCGTGCAG CTCAGGAGCC TCCGTCTCAC CTATCGCAAC 
CTATCGGGCC CTGATAAGCG GCTGGTGACG CTGCGACTGC CTGCCTCGCT CGCTGAGTAC 
ACGGTCACCC AGCTGCGGCC CAACGCCACT TACTCCGTCT GTGTCATGCC TTTGGGGCCC 
GGGCGGGTGC CGGAGGGCGA GGAGGCCTGC GGGGAGGCCC ATACACCCCC AGCCGTCCAC 
TCCAACCACG CCCCAGTCAC CCAGGCCCGC GAGGGCAACC TGCCGCTCCT CATTGCGCCC 
GCCCTGGCCG CGGTGCTCCT GGCCGCGCTG GCTGCGGTGG GGGCAGCCTA CTGTGTGCGG 
CGGGGGCGGG CCATGGCAGC AGCGGCTCAG GACAAAGGGC AGGTGGGGCC AGGGGCTGGG 
CCCCTGGAAC TGGAGGGAGT GAAGGTCCCC TTGGAGCCAG GCCCGAAGGC AACAGAGGGC 
GGTGGAGAGG CCCTGCCCAG CGGGTCTGAG TGTGAGGTGC CACTCATGGG CTTCCCAGGG 
CCTGGCCTCC AGTCACCCCT CCACGCAAAG CCCTACATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells.
Cell stem cell22(1)104-118.e6(2018 Jan)
Man J,Yu X,Huang H,Zhou W,Xiang C,Huang H,Miele L,Liu Z,Bebek G,Bao S,Yu JS

Exosomal transfer of vasorin expressed in hepatocellular carcinoma cells promotes migration of human umbilical vein endothelial cells.
International journal of biological sciences11(8)961-9(2015)
Huang A,Dong J,Li S,Wang C,Ding H,Li H,Su X,Ge X,Sun L,Bai C,Shen X,Fang T,Li J,Shao N

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

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VASN cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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