GTF3C6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GTF3C6
Entrez Gene ID	112495
Full Name	general transcription factor IIIC subunit 6
Synonyms	C6orf51,TFIIIC35,bA397G5.3
General protein information	Preferred Names general transcription factor IIIC subunit 6 Names general transcription factor 3C polypeptide 6 TFIIIC 35 kDa subunit general transcription factor IIIC, polypeptide 6, alpha 35kDa transcription factor IIIC 35 kDa subunit transcription factor IIIC 35kDa transcription factor IIIC subunit 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q21
Summary	RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.[supplied by OMIM, Mar 2008].
Disorder MIM:	611784

mRNA and Protein(s)

mRNA	Protein	Name
NM_138408.4	NP_612417.1	general transcription factor 3C polypeptide 6
NM_138408.3	NP_612417.1	general transcription factor 3C polypeptide 6

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GTF3C6	XP_518690.2
	LOC696512	XP_001087346.1
Bos taurus (cattle)	GTF3C6	XP_002690159.1
Mus musculus (house mouse)	Gtf3c6	NP_080389.2
Rattus norvegicus (Norway rat)	Gtf3c6	NP_001102007.1
Gallus gallus (chicken)	GTF3C6	NP_001026247.1
Homo sapiens (human)	GTF3C6	NP_612417.1
Canis lupus familiaris (dog)	GTF3C6	XP_005627770.1

Gene Ontology
Bibliography

Related articles in PubMed

Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC.
Dumay-Odelot H, Marck C, Durrieu-Gaillard S, Lefebvre O, Jourdain S, Prochazkova M, Pflieger A, Teichmann M
The Journal of biological chemistry282(23)17179-89(2007 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GTF3C6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GTF3C6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31370	NM_138408.4 Latest version!	Homo sapiens general transcription factor IIIC subunit 6 (GTF3C6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu31370	NM_138408.3	Homo sapiens general transcription factor IIIC subunit 6 (GTF3C6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GTF3C6 ( NM_138408.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_612417.1 Homo sapiens general transcription factor IIIC subunit 6 (GTF3C6), mRNA.

Price & Availability↑

CloneID	OHu31370
Clone ID Related Accession (Same CDS sequence)	NM_138408.4 , NM_138408.3
Accession Version	NM_138408.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	general transcription factor 3C polypeptide 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF361496.1. On Nov 22, 2018 this sequence version replaced NM_138408.3. ##Evidence-Data-START## Transcript exon combination :: AF361496.1, SRR1163657.272789.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000329970.8/ ENSP00000357863.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCGG CGGCGGACGA GCGGAGTCCA GAGGACGGAG AAGACGAGGA AGAGGAGGAG 
CAGTTGGTTC TGGTGGAATT ATCAGGAATT ATTGATTCAG ACTTCCTCTC AAAATGTGAA 
AATAAATGCA AGGTTTTGGG CATTGACACT GAGAGGCCCA TTCTGCAAGT GGACAGCTGT 
GTCTTTGCTG GGGAGTATGA AGACACTCTA GGGACCTGTG TTATATTTGA AGAAAATGTT 
GAACATGCTG ATACAGAAGG CAATAATAAA ACAGTGCTAA AATATAAATG CCATACAATG 
AAGAAGCTCA GCATGACAAG AACTCTCCTG ACAGAGAAGA AGGAAGGAGA AGAAAACATA 
GGTGGGGTGG AATGGCTGCA AATAAAGGAT AATGATTTCT CCTATCGACC CAACATGATT 
TGTAACTTTC TACATGAAAA TGAAGACGAA GAAGTGGTAG CTTCAGCCCC AGATAAATCT 
TTGGAATTGG AAGAGGAAGA GATTCAAATG AACGACAGTT CAAACCTGAG TTGTGAACAG 
GAGAAACCAA TGCACTTGGA AATAGAAGAT TCTGGTCCTC TTATTGATAT ACCTTCTGAG 
ACAGAAGGTT CTGTTTTTAT GGAAACTCAA ATGCTGCCTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612417.1
CDS	65..706
Translation	MAAAADERSPEDGEDEEEEEQLVLVELSGIIDSDFLSKCENKCKVLGIDTERPILQVDSCVFAGEYEDTLGTCVIFEENVEHADTEGNNKTVLKYKCHTMKKLSMTRTLLTEKKEGEENIGGVEWLQIKDNDFSYRPNMICNFLHENEDEEVVASAPDKSLELEEEEIQMNDSSNLSCEQEKPMHLEIEDSGPLIDIPSETEGSVFMETQMLP

Target ORF information:

RefSeq Version	NM_138408.4
Organism	Homo sapiens(human)
Definition	Homo sapiens general transcription factor IIIC subunit 6 (GTF3C6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138408.4

ORF Insert Sequence:

ATGGCGGCGG CGGCGGACGA GCGGAGTCCA GAGGACGGAG AAGACGAGGA AGAGGAGGAG 
CAGTTGGTTC TGGTGGAATT ATCAGGAATT ATTGATTCAG ACTTCCTCTC AAAATGTGAA 
AATAAATGCA AGGTTTTGGG CATTGACACT GAGAGGCCCA TTCTGCAAGT GGACAGCTGT 
GTCTTTGCTG GGGAGTATGA AGACACTCTA GGGACCTGTG TTATATTTGA AGAAAATGTT 
GAACATGCTG ATACAGAAGG CAATAATAAA ACAGTGCTAA AATATAAATG CCATACAATG 
AAGAAGCTCA GCATGACAAG AACTCTCCTG ACAGAGAAGA AGGAAGGAGA AGAAAACATA 
GGTGGGGTGG AATGGCTGCA AATAAAGGAT AATGATTTCT CCTATCGACC CAACATGATT 
TGTAACTTTC TACATGAAAA TGAAGACGAA GAAGTGGTAG CTTCAGCCCC AGATAAATCT 
TTGGAATTGG AAGAGGAAGA GATTCAAATG AACGACAGTT CAAACCTGAG TTGTGAACAG 
GAGAAACCAA TGCACTTGGA AATAGAAGAT TCTGGTCCTC TTATTGATAT ACCTTCTGAG 
ACAGAAGGTT CTGTTTTTAT GGAAACTCAA ATGCTGCCTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GTF3C6 ( NM_138408.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_612417.1 Homo sapiens general transcription factor IIIC subunit 6 (GTF3C6), mRNA.

Price & Availability↑

CloneID	OHu31370
Clone ID Related Accession (Same CDS sequence)	NM_138408.4 , NM_138408.3
Accession Version	NM_138408.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	general transcription factor 3C polypeptide 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF361496.1 and BQ269752.1. On Jan 22, 2009 this sequence version replaced NM_138408.2. ##Evidence-Data-START## Transcript exon combination :: AF361492.1, SRR1163658.244658.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGG CGGCGGACGA GCGGAGTCCA GAGGACGGAG AAGACGAGGA AGAGGAGGAG 
CAGTTGGTTC TGGTGGAATT ATCAGGAATT ATTGATTCAG ACTTCCTCTC AAAATGTGAA 
AATAAATGCA AGGTTTTGGG CATTGACACT GAGAGGCCCA TTCTGCAAGT GGACAGCTGT 
GTCTTTGCTG GGGAGTATGA AGACACTCTA GGGACCTGTG TTATATTTGA AGAAAATGTT 
GAACATGCTG ATACAGAAGG CAATAATAAA ACAGTGCTAA AATATAAATG CCATACAATG 
AAGAAGCTCA GCATGACAAG AACTCTCCTG ACAGAGAAGA AGGAAGGAGA AGAAAACATA 
GGTGGGGTGG AATGGCTGCA AATAAAGGAT AATGATTTCT CCTATCGACC CAACATGATT 
TGTAACTTTC TACATGAAAA TGAAGACGAA GAAGTGGTAG CTTCAGCCCC AGATAAATCT 
TTGGAATTGG AAGAGGAAGA GATTCAAATG AACGACAGTT CAAACCTGAG TTGTGAACAG 
GAGAAACCAA TGCACTTGGA AATAGAAGAT TCTGGTCCTC TTATTGATAT ACCTTCTGAG 
ACAGAAGGTT CTGTTTTTAT GGAAACTCAA ATGCTGCCTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612417.1
CDS	211..852
Translation	MAAAADERSPEDGEDEEEEEQLVLVELSGIIDSDFLSKCENKCKVLGIDTERPILQVDSCVFAGEYEDTLGTCVIFEENVEHADTEGNNKTVLKYKCHTMKKLSMTRTLLTEKKEGEENIGGVEWLQIKDNDFSYRPNMICNFLHENEDEEVVASAPDKSLELEEEEIQMNDSSNLSCEQEKPMHLEIEDSGPLIDIPSETEGSVFMETQMLP

Target ORF information:

RefSeq Version	NM_138408.3
Organism	Homo sapiens(human)
Definition	Homo sapiens general transcription factor IIIC subunit 6 (GTF3C6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138408.3

ORF Insert Sequence:

ATGGCGGCGG CGGCGGACGA GCGGAGTCCA GAGGACGGAG AAGACGAGGA AGAGGAGGAG 
CAGTTGGTTC TGGTGGAATT ATCAGGAATT ATTGATTCAG ACTTCCTCTC AAAATGTGAA 
AATAAATGCA AGGTTTTGGG CATTGACACT GAGAGGCCCA TTCTGCAAGT GGACAGCTGT 
GTCTTTGCTG GGGAGTATGA AGACACTCTA GGGACCTGTG TTATATTTGA AGAAAATGTT 
GAACATGCTG ATACAGAAGG CAATAATAAA ACAGTGCTAA AATATAAATG CCATACAATG 
AAGAAGCTCA GCATGACAAG AACTCTCCTG ACAGAGAAGA AGGAAGGAGA AGAAAACATA 
GGTGGGGTGG AATGGCTGCA AATAAAGGAT AATGATTTCT CCTATCGACC CAACATGATT 
TGTAACTTTC TACATGAAAA TGAAGACGAA GAAGTGGTAG CTTCAGCCCC AGATAAATCT 
TTGGAATTGG AAGAGGAAGA GATTCAAATG AACGACAGTT CAAACCTGAG TTGTGAACAG 
GAGAAACCAA TGCACTTGGA AATAGAAGAT TCTGGTCCTC TTATTGATAT ACCTTCTGAG 
ACAGAAGGTT CTGTTTTTAT GGAAACTCAA ATGCTGCCTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC.
The Journal of biological chemistry282(23)17179-89(2007 Jun)
Dumay-Odelot H,Marck C,Durrieu-Gaillard S,Lefebvre O,Jourdain S,Prochazkova M,Pflieger A,Teichmann M

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GTF3C6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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