SCGB1D1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SCGB1D1
Entrez Gene ID	10648
Full Name	secretoglobin family 1D member 1
Synonyms	LIPA,LPHA,LPNA
General protein information	Preferred Names secretoglobin family 1D member 1 Names secretoglobin family 1D member 1 lipophilin A (uteroglobin family member) lipophilin-A prostatein-like lipophilin A
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q12.3
Summary	The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. This gene product represents one component of a heterodimeric molecule present in human tears whose elution profile is consistent with prostatein, a tetrameric molecule composed of three peptide components in heterodimers. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 15, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008].
Disorder MIM:	615060

mRNA and Protein(s)

mRNA	Protein	Name
NM_006552.1	NP_006543.1	secretoglobin family 1D member 1 precursor
NM_006552.2	NP_006543.1	secretoglobin family 1D member 1 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SCGB1D1	XP_001151964.1
	SCGB1D1	XP_001116554.1
Homo sapiens (human)	SCGB1D1	NP_006543.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.
Guan W, Steffen BT, Lemaitre RN, Wu JHY, Tanaka T, Manichaikul A, Foy M, Rich SS, Wang L, Nettleton JA, Tang W, Gu X, Bandinelli S, King IB, McKnight B, Psaty BM, Siscovick D, Djousse L, Chen YI, Ferrucci L, Fornage M, Mozafarrian D, Tsai MY, Steffen LM
Circulation. Cardiovascular genetics7(3)321-331(2014 Jun)

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma na?ve to therapy.
Pieragostino D, Agnifili L, Fasanella V, D'Aguanno S, Mastropasqua R, Di Ilio C, Sacchetta P, Urbani A, Del Boccio P
Molecular bioSystems9(6)1108-16(2013 Jun)

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.
B?hm D, Keller K, Pieter J, Boehm N, Wolters D, Siggelkow W, Lebrecht A, Schmidt M, K?lbl H, Pfeiffer N, Grus FH
Oncology reports28(2)429-38(2012 Aug)

Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily.
Jackson BC, Thompson DC, Wright MW, McAndrews M, Bernard A, Nebert DW, Vasiliou V
Human genomics5(6)691-702(2011 Oct)

Lipophilins: human peptides homologous to rat prostatein.
Zhao C, Nguyen T, Yusifov T, Glasgow BJ, Lehrer RI
Biochemical and biophysical research communications256(1)147-55(1999 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SCGB1D1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SCGB1D1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29695	NM_006552.2 Latest version!	Homo sapiens secretoglobin family 1D member 1 (SCGB1D1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu29695	NM_006552.1	Homo sapiens secretoglobin family 1D member 1 (SCGB1D1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SCGB1D1 ( NM_006552.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_006543.1 Homo sapiens secretoglobin family 1D member 1 (SCGB1D1), mRNA.

Price & Availability↑

CloneID	OHu29695
Clone ID Related Accession (Same CDS sequence)	NM_006552.1 , NM_006552.2
Accession Version	NM_006552.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 273bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	secretoglobin family 1D member 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ224171.1. ##Evidence-Data-START## Transcript exon combination :: BC069170.1, AJ224171.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465412 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTGT CGGTGTGTCT CCTGCTGCTC ACGCTGGCCC TTTGCTGCTA CCGGGCAAAT 
GCAGTGGTCT GCCAAGCTCT TGGTTCTGAA ATCACAGGCT TCTTATTAGC TGGAAAACCT 
GTGTTCAAGT TCCAACTTGC CAAATTTAAG GCACCTCTGG AAGCTGTTGC AGCCAAGATG 
GAAGTGAAGA AATGCGTGGA TACGATGGCC TATGAGAAAA GAGTGCTAAT TACAAAAACA 
TTGGGAAAAA TAGCAGAGAA ATGTGATCGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006543.1
CDS	48..320
Translation	MRLSVCLLLLTLALCCYRANAVVCQALGSEITGFLLAGKPVFKFQLAKFKAPLEAVAAKMEVKKCVDTMAYEKRVLITKTLGKIAEKCDR

Target ORF information:

RefSeq Version	NM_006552.1
Organism	Homo sapiens(human)
Definition	Homo sapiens secretoglobin family 1D member 1 (SCGB1D1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006552.1

ORF Insert Sequence:

ATGAGGCTGT CGGTGTGTCT CCTGCTGCTC ACGCTGGCCC TTTGCTGCTA CCGGGCAAAT 
GCAGTGGTCT GCCAAGCTCT TGGTTCTGAA ATCACAGGCT TCTTATTAGC TGGAAAACCT 
GTGTTCAAGT TCCAACTTGC CAAATTTAAG GCACCTCTGG AAGCTGTTGC AGCCAAGATG 
GAAGTGAAGA AATGCGTGGA TACGATGGCC TATGAGAAAA GAGTGCTAAT TACAAAAACA 
TTGGGAAAAA TAGCAGAGAA ATGTGATCGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCGB1D1 ( NM_006552.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_006543.1 Homo sapiens secretoglobin family 1D member 1 (SCGB1D1), mRNA.

Price & Availability↑

CloneID	OHu29695
Clone ID Related Accession (Same CDS sequence)	NM_006552.1 , NM_006552.2
Accession Version	NM_006552.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 273bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-29
Organism	Homo sapiens(human)
Product	secretoglobin family 1D member 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP002793.4, AJ224171.1 and AP003306.2. On May 17, 2019 this sequence version replaced NM_006552.1. ##Evidence-Data-START## Transcript exon combination :: BC062693.1, CB984908.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465412 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000306238.3/ ENSP00000303070.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGCTGT CGGTGTGTCT CCTGCTGCTC ACGCTGGCCC TTTGCTGCTA CCGGGCAAAT 
GCAGTGGTCT GCCAAGCTCT TGGTTCTGAA ATCACAGGCT TCTTATTAGC TGGAAAACCT 
GTGTTCAAGT TCCAACTTGC CAAATTTAAG GCACCTCTGG AAGCTGTTGC AGCCAAGATG 
GAAGTGAAGA AATGCGTGGA TACGATGGCC TATGAGAAAA GAGTGCTAAT TACAAAAACA 
TTGGGAAAAA TAGCAGAGAA ATGTGATCGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006543.1
CDS	70..342
Translation	MRLSVCLLLLTLALCCYRANAVVCQALGSEITGFLLAGKPVFKFQLAKFKAPLEAVAAKMEVKKCVDTMAYEKRVLITKTLGKIAEKCDR

Target ORF information:

RefSeq Version	NM_006552.2
Organism	Homo sapiens(human)
Definition	Homo sapiens secretoglobin family 1D member 1 (SCGB1D1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006552.2

ORF Insert Sequence:

ATGAGGCTGT CGGTGTGTCT CCTGCTGCTC ACGCTGGCCC TTTGCTGCTA CCGGGCAAAT 
GCAGTGGTCT GCCAAGCTCT TGGTTCTGAA ATCACAGGCT TCTTATTAGC TGGAAAACCT 
GTGTTCAAGT TCCAACTTGC CAAATTTAAG GCACCTCTGG AAGCTGTTGC AGCCAAGATG 
GAAGTGAAGA AATGCGTGGA TACGATGGCC TATGAGAAAA GAGTGCTAAT TACAAAAACA 
TTGGGAAAAA TAGCAGAGAA ATGTGATCGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium.
Circulation. Cardiovascular genetics7(3)321-331(2014 Jun)
Guan W,Steffen BT,Lemaitre RN,Wu JHY,Tanaka T,Manichaikul A,Foy M,Rich SS,Wang L,Nettleton JA,Tang W,Gu X,Bandinelli S,King IB,McKnight B,Psaty BM,Siscovick D,Djousse L,Chen YI,Ferrucci L,Fornage M,Mozafarrian D,Tsai MY,Steffen LM

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma na?ve to therapy.
Molecular bioSystems9(6)1108-16(2013 Jun)
Pieragostino D,Agnifili L,Fasanella V,D'Aguanno S,Mastropasqua R,Di Ilio C,Sacchetta P,Urbani A,Del Boccio P

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.
Oncology reports28(2)429-38(2012 Aug)
B?hm D,Keller K,Pieter J,Boehm N,Wolters D,Siggelkow W,Lebrecht A,Schmidt M,K?lbl H,Pfeiffer N,Grus FH

Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily.
Human genomics5(6)691-702(2011 Oct)
Jackson BC,Thompson DC,Wright MW,McAndrews M,Bernard A,Nebert DW,Vasiliou V

Lipophilins: human peptides homologous to rat prostatein.
Biochemical and biophysical research communications256(1)147-55(1999 Mar)
Zhao C,Nguyen T,Yusifov T,Glasgow BJ,Lehrer RI

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SCGB1D1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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