BATF cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BATF
Entrez Gene ID	10538
Full Name	basic leucine zipper ATF-like transcription factor
Synonyms	B-ATF,BATF1,SFA-2,SFA2
General protein information	Preferred Names basic leucine zipper ATF-like transcription factor Names basic leucine zipper transcriptional factor ATF-like B-cell-activating transcription factor SF-HT-activated gene 2 protein activating transcription factor B basic leucine zipper transcription factor, ATF-like
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q24.3
Summary	The protein encoded by this gene is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events. [provided by RefSeq, Jul 2008].
Disorder MIM:	612476

mRNA and Protein(s)

mRNA	Protein	Name
NM_006399.4	NP_006390.1	basic leucine zipper transcriptional factor ATF-like
NM_006399.5	NP_006390.1	basic leucine zipper transcriptional factor ATF-like
NM_006399.3	NP_006390.1	basic leucine zipper transcriptional factor ATF-like

Pathways from BioSystems

Homologies

	BATF	XP_001099352.1
Bos taurus (cattle)	BATF	NP_001193207.1
Mus musculus (house mouse)	Batf	NP_058047.1
Gallus gallus (chicken)	BATF	XP_421279.3
Canis lupus familiaris (dog)	BATF	XP_854763.2
Xenopus tropicalis (tropical clawed frog)	batf	XP_002938637.1
Pan troglodytes (chimpanzee)	BATF	XP_001160120.1
Danio rerio (zebrafish)	batf	NP_001038524.1
Homo sapiens (human)	BATF	NP_006390.1
Rattus norvegicus (Norway rat)	Batf	NP_001100218.1

Gene Ontology
Bibliography

Related articles in PubMed

Increased BATF expression is associated with the severity of liver damage in patients with chronic hepatitis B.
Wang LY, Fan YC, Zhao J, Ji XF, Wang K
Clinical and experimental medicine(2017 Nov)

Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction.
Rhee J, Park SH, Kim SK, Kim JH, Ha CW, Chun CH, Chun JS
Annals of the rheumatic diseases76(2)427-434(2017 Feb)

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, Yi S, Tyagi T, Sheykhkarimli D, Roth JF, Wong C, Musa L, Snider J, Liu YC, Yu H, Braun P, Stagljar I, Hao T, Calderwood MA, Pelletier L, Aloy P, Hill DE, Vidal M, Roth FP
Molecular systems biology12(4)863(2016 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

BATF/JUN-B and BATF/C-JUN complexes play important roles in OA cartilage destruction through regulating anabolic and catabolic gene expression in chondrocytes.
Title: Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction.

BATF plays a key role in the differentiation of T helper cell subsets and Ig class-switching. Apart from that we suggest an important function in mast cell development and in murine models of allergic asthma, it was observed that mice deficient for Batf are protected from the disease. Hence, the previous findings on BATF make it an interesting target for the treatment of Th cell-derived-cytokine-driven diseases.
Title: The transcription factor BATF modulates cytokine-mediated responses in T cells.

Retinoic acid signaling and BATF productions are activated in IgAN patients compared with controls.
Title: Regulation of IgA Class Switch Recombination in Immunoglobulin A Nephropathy: Retinoic Acid Signaling and BATF.

data strongly support a model in which EBNA3A is tethered to DNA through a BATF-containing protein complexes to enable continuous cell proliferation
Title: Epstein-Barr virus nuclear antigen 3A partially coincides with EBNA3C genome-wide and is tethered to DNA through BATF complexes.

Increased expression of the Th17-IL-6R/pSTAT3/BATF/RorgammaT-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung
Title: Increased expression of the Th17-IL-6R/pSTAT3/BATF/Ror?T-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung.

The following BATF gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BATF cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12198	NM_006399.5 Latest version!	Homo sapiens basic leucine zipper ATF-like transcription factor (BATF), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu12198	NM_006399.4	Homo sapiens basic leucine zipper ATF-like transcription factor (BATF), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu12198	NM_006399.3	Homo sapiens basic leucine zipper ATF-like transcription factor (BATF), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BATF ( NM_006399.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006390.1 Homo sapiens basic leucine zipper ATF-like transcription factor (BATF), mRNA.

Price & Availability↑

CloneID	OHu12198
Clone ID Related Accession (Same CDS sequence)	NM_006399.4 , NM_006399.5 , NM_006399.3
Accession Version	NM_006399.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-06
Organism	Homo sapiens(human)
Product	basic leucine zipper transcriptional factor ATF-like
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP235761.1, U15460.1, BC032294.1 and AC007182.3. On May 17, 2019 this sequence version replaced NM_006399.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.425061.1, SRR1163655.671609.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCTCACA GCTCCGACAG CAGTGACTCC AGCTTCAGCC GCTCTCCTCC CCCTGGCAAA 
CAGGACTCAT CTGATGATGT GAGAAGAGTT CAGAGGAGGG AGAAAAATCG TATTGCCGCC 
CAGAAGAGCC GACAGAGGCA GACACAGAAG GCCGACACCC TGCACCTGGA GAGCGAAGAC 
CTGGAGAAAC AGAACGCGGC TCTACGCAAG GAGATCAAGC AGCTCACAGA GGAACTGAAG 
TACTTCACGT CGGTGCTGAA CAGCCACGAG CCCCTGTGCT CGGTGCTGGC CGCCAGCACG 
CCCTCGCCCC CCGAGGTGGT GTACAGCGCC CACGCATTCC ACCAACCTCA TGTCAGCTCC 
CCGCGCTTCC AGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006390.1
CDS	215..592
Translation	MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAASTPSPPEVVYSAHAFHQPHVSSPRFQP

Target ORF information:

RefSeq Version	NM_006399.4
Organism	Homo sapiens(human)
Definition	Homo sapiens basic leucine zipper ATF-like transcription factor (BATF), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006399.4

ORF Insert Sequence:

ATGCCTCACA GCTCCGACAG CAGTGACTCC AGCTTCAGCC GCTCTCCTCC CCCTGGCAAA 
CAGGACTCAT CTGATGATGT GAGAAGAGTT CAGAGGAGGG AGAAAAATCG TATTGCCGCC 
CAGAAGAGCC GACAGAGGCA GACACAGAAG GCCGACACCC TGCACCTGGA GAGCGAAGAC 
CTGGAGAAAC AGAACGCGGC TCTACGCAAG GAGATCAAGC AGCTCACAGA GGAACTGAAG 
TACTTCACGT CGGTGCTGAA CAGCCACGAG CCCCTGTGCT CGGTGCTGGC CGCCAGCACG 
CCCTCGCCCC CCGAGGTGGT GTACAGCGCC CACGCATTCC ACCAACCTCA TGTCAGCTCC 
CCGCGCTTCC AGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BATF ( NM_006399.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006390.1 Homo sapiens basic leucine zipper ATF-like transcription factor (BATF), mRNA.

Price & Availability↑

CloneID	OHu12198
Clone ID Related Accession (Same CDS sequence)	NM_006399.4 , NM_006399.5 , NM_006399.3
Accession Version	NM_006399.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Homo sapiens(human)
Product	basic leucine zipper transcriptional factor ATF-like
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP235761.1, U15460.1 and BC032294.1. On Dec 13, 2008 this sequence version replaced NM_006399.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC032294.1, SRR1163655.80871.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTCACA GCTCCGACAG CAGTGACTCC AGCTTCAGCC GCTCTCCTCC CCCTGGCAAA 
CAGGACTCAT CTGATGATGT GAGAAGAGTT CAGAGGAGGG AGAAAAATCG TATTGCCGCC 
CAGAAGAGCC GACAGAGGCA GACACAGAAG GCCGACACCC TGCACCTGGA GAGCGAAGAC 
CTGGAGAAAC AGAACGCGGC TCTACGCAAG GAGATCAAGC AGCTCACAGA GGAACTGAAG 
TACTTCACGT CGGTGCTGAA CAGCCACGAG CCCCTGTGCT CGGTGCTGGC CGCCAGCACG 
CCCTCGCCCC CCGAGGTGGT GTACAGCGCC CACGCATTCC ACCAACCTCA TGTCAGCTCC 
CCGCGCTTCC AGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006390.1
CDS	243..620
Translation	MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAASTPSPPEVVYSAHAFHQPHVSSPRFQP

Target ORF information:

RefSeq Version	NM_006399.3
Organism	Homo sapiens(human)
Definition	Homo sapiens basic leucine zipper ATF-like transcription factor (BATF), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006399.3

ORF Insert Sequence:

ATGCCTCACA GCTCCGACAG CAGTGACTCC AGCTTCAGCC GCTCTCCTCC CCCTGGCAAA 
CAGGACTCAT CTGATGATGT GAGAAGAGTT CAGAGGAGGG AGAAAAATCG TATTGCCGCC 
CAGAAGAGCC GACAGAGGCA GACACAGAAG GCCGACACCC TGCACCTGGA GAGCGAAGAC 
CTGGAGAAAC AGAACGCGGC TCTACGCAAG GAGATCAAGC AGCTCACAGA GGAACTGAAG 
TACTTCACGT CGGTGCTGAA CAGCCACGAG CCCCTGTGCT CGGTGCTGGC CGCCAGCACG 
CCCTCGCCCC CCGAGGTGGT GTACAGCGCC CACGCATTCC ACCAACCTCA TGTCAGCTCC 
CCGCGCTTCC AGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BATF ( NM_006399.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_006390.1 Homo sapiens basic leucine zipper ATF-like transcription factor (BATF), mRNA.

Price & Availability↑

CloneID	OHu12198
Clone ID Related Accession (Same CDS sequence)	NM_006399.4 , NM_006399.5 , NM_006399.3
Accession Version	NM_006399.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-14
Organism	Homo sapiens(human)
Product	basic leucine zipper transcriptional factor ATF-like
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP235761.1, U15460.1 and BC032294.1. On Aug 31, 2019 this sequence version replaced NM_006399.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC032294.1, CD743175.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCTCACA GCTCCGACAG CAGTGACTCC AGCTTCAGCC GCTCTCCTCC CCCTGGCAAA 
CAGGACTCAT CTGATGATGT GAGAAGAGTT CAGAGGAGGG AGAAAAATCG TATTGCCGCC 
CAGAAGAGCC GACAGAGGCA GACACAGAAG GCCGACACCC TGCACCTGGA GAGCGAAGAC 
CTGGAGAAAC AGAACGCGGC TCTACGCAAG GAGATCAAGC AGCTCACAGA GGAACTGAAG 
TACTTCACGT CGGTGCTGAA CAGCCACGAG CCCCTGTGCT CGGTGCTGGC CGCCAGCACG 
CCCTCGCCCC CCGAGGTGGT GTACAGCGCC CACGCATTCC ACCAACCTCA TGTCAGCTCC 
CCGCGCTTCC AGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006390.1
CDS	215..592
Translation	MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAASTPSPPEVVYSAHAFHQPHVSSPRFQP

Target ORF information:

RefSeq Version	NM_006399.5
Organism	Homo sapiens(human)
Definition	Homo sapiens basic leucine zipper ATF-like transcription factor (BATF), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006399.5

ORF Insert Sequence:

ATGCCTCACA GCTCCGACAG CAGTGACTCC AGCTTCAGCC GCTCTCCTCC CCCTGGCAAA 
CAGGACTCAT CTGATGATGT GAGAAGAGTT CAGAGGAGGG AGAAAAATCG TATTGCCGCC 
CAGAAGAGCC GACAGAGGCA GACACAGAAG GCCGACACCC TGCACCTGGA GAGCGAAGAC 
CTGGAGAAAC AGAACGCGGC TCTACGCAAG GAGATCAAGC AGCTCACAGA GGAACTGAAG 
TACTTCACGT CGGTGCTGAA CAGCCACGAG CCCCTGTGCT CGGTGCTGGC CGCCAGCACG 
CCCTCGCCCC CCGAGGTGGT GTACAGCGCC CACGCATTCC ACCAACCTCA TGTCAGCTCC 
CCGCGCTTCC AGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Increased BATF expression is associated with the severity of liver damage in patients with chronic hepatitis B.
Clinical and experimental medicine(2017 Nov)
Wang LY,Fan YC,Zhao J,Ji XF,Wang K

Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction.
Annals of the rheumatic diseases76(2)427-434(2017 Feb)
Rhee J,Park SH,Kim SK,Kim JH,Ha CW,Chun CH,Chun JS

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Molecular systems biology12(4)863(2016 Apr)
Yachie N,Petsalaki E,Mellor JC,Weile J,Jacob Y,Verby M,Ozturk SB,Li S,Cote AG,Mosca R,Knapp JJ,Ko M,Yu A,Gebbia M,Sahni N,Yi S,Tyagi T,Sheykhkarimli D,Roth JF,Wong C,Musa L,Snider J,Liu YC,Yu H,Braun P,Stagljar I,Hao T,Calderwood MA,Pelletier L,Aloy P,Hill DE,Vidal M,Roth FP

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BATF cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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