SEMA3C cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SEMA3C
Entrez Gene ID	10512
Full Name	semaphorin 3C
Synonyms	SEMAE,SemE
General protein information	Preferred Names semaphorin 3C Names semaphorin-3C sema E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C semaphorin E
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q21.11
Summary	This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease. [provided by RefSeq, May 2017].
Disorder MIM:	602645

mRNA and Protein(s)

mRNA	Protein	Name
NM_006379.4	NP_006370.1	semaphorin-3C isoform 2 precursor
NM_001350120.1	NP_001337049.1	semaphorin-3C isoform 1
NM_006379.5	NP_006370.1	semaphorin-3C isoform 2 precursor
NM_006379.3	NP_006370.1	semaphorin-3C precursor
NM_001350121.1	NP_001337050.1	semaphorin-3C isoform 3
XM_005250113.2	XP_005250170.1	semaphorin-3C isoform X1
NM_001350120.2	NP_001337049.1	semaphorin-3C isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SEMA3C	NP_006370.1
Mus musculus (house mouse)	Sema3c	NP_038685.3
Pan troglodytes (chimpanzee)	SEMA3C	XP_001159729.2
Danio rerio (zebrafish)	sema3c	XP_692847.3
	SEMA3C	XP_001108385.1
Canis lupus familiaris (dog)	SEMA3C	XP_533139.2
Rattus norvegicus (Norway rat)	Sema3c	NP_001100048.1
Xenopus tropicalis (tropical clawed frog)	sema3c	XP_002933132.1
Bos taurus (cattle)	SEMA3C	NP_001094552.1
Gallus gallus (chicken)	SEMA3C	NP_989574.1

Gene Ontology
Bibliography

Related articles in PubMed

Class 3 semaphorins are transcriptionally regulated by 1,25(OH)
Ryyn?nen J, Kriebitzsch C, Meyer MB, Janssens I, Pike JW, Verlinden L, Verstuyf A
The Journal of steroid biochemistry and molecular biology173185-193(2017 10)

Semaphorin 3?C drives epithelial-to-mesenchymal transition, invasiveness, and stem-like characteristics in prostate cells.
Tam KJ, Hui DHF, Lee WW, Dong M, Tombe T, Jiao IZF, Khosravi S, Takeuchi A, Peacock JW, Ivanova L, Moskalev I, Gleave ME, Buttyan R, Cox ME, Ong CJ
Scientific reports7(1)11501(2017 Sep)

Increased semaphorin 3c expression promotes tumor growth and metastasis in pancreatic ductal adenocarcinoma by activating the ERK1/2 signaling pathway.
Xu X, Zhao Z, Guo S, Li J, Liu S, You Y, Ni B, Wang H, Bie P
Cancer letters39712-22(2017 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Aberrant expression of sema3c is correlated with poor prognosis of pancreatic ductal adenocarcinoma patients and promotes tumor growth and metastasis by activating ERK1/2 signaling pathway.
Title: Increased semaphorin 3c expression promotes tumor growth and metastasis in pancreatic ductal adenocarcinoma by activating the ERK1/2 signaling pathway.

The exploratory genome-wide association studies confirmed APOE and identified the novel loci: rs2525776 near SEMA3C (P = 1 x 10(-8), OR = 3.3 [2.1-5.1]).
Title: Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease.

SEMA3C plays a role in the progression of breast cancer and may positively influence breast cancer cell adhesion, invasion and proliferation, as well as being associated with grade of disease and estrogen receptor status.
Title: Expression of Semaphorin 3C in Breast Cancer and its Impact on Adhesion and Invasion of Breast Cancer Cells.

FR-sema3C could perhaps be used for the treatment of AMD.
Title: A Sema3C Mutant Resistant to Cleavage by Furin (FR-Sema3C) Inhibits Choroidal Neovascularization.

Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels.
Title: Class 3 semaphorins expression and association with innervation and angiogenesis within the degenerate human intervertebral disc.

The following SEMA3C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SEMA3C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05543	NM_006379.5 Latest version!	Homo sapiens semaphorin 3C (SEMA3C), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu41339	NM_001350121.1 Latest version!	Homo sapiens semaphorin 3C (SEMA3C), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu41339	XM_005250113.2 Latest version!	Homo sapiens semaphorin 3C (SEMA3C), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu102647	NM_001350120.2 Latest version!	Homo sapiens semaphorin 3C (SEMA3C), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu05543	NM_006379.4	Homo sapiens semaphorin 3C (SEMA3C), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu05543	NM_006379.3	Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (SEMA3C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu102647	NM_001350120.1	Homo sapiens semaphorin 3C (SEMA3C), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SEMA3C ( NM_006379.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006370.1 Homo sapiens semaphorin 3C (SEMA3C), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu05543
Clone ID Related Accession (Same CDS sequence)	NM_006379.4 , NM_006379.5 , NM_006379.3
Accession Version	NM_006379.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2256bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-29
Organism	Homo sapiens(human)
Product	semaphorin-3C isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB000220.1, AK304294.1, BC030690.1, CN334969.1, CN334967.1, AA853650.1, BM473251.1 and AI491966.1. This sequence is a reference standard in the RefSeqGene project. On May 6, 2017 this sequence version replaced NM_006379.3. Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGGCATTCC GGACAATTTG CGTGTTGGTT GGAGTATTTA TTTGTTCTAT CTGTGTGAAA 
GGATCTTCCC AGCCCCAAGC AAGAGTTTAT TTAACATTTG ATGAACTTCG AGAAACCAAG 
ACCTCTGAAT ACTTCAGCCT TTCCCACCAT CCTTTAGACT ACAGGATTTT ATTAATGGAT 
GAAGATCAGG ACCGGATATA TGTGGGAAGC AAAGATCACA TTCTTTCCCT GAATATTAAC 
AATATAAGTC AAGAAGCTTT GAGTGTTTTC TGGCCAGCAT CTACAATCAA AGTTGAAGAA 
TGCAAAATGG CTGGCAAAGA TCCCACACAC GGCTGTGGGA ACTTTGTCCG TGTAATTCAG 
ACTTTCAATC GCACACATTT GTATGTCTGT GGGAGTGGCG CTTTCAGTCC TGTCTGTACT 
TACTTGAACA GAGGGAGGAG ATCAGAGGAC CAAGTTTTCA TGATTGACTC CAAGTGTGAA 
TCTGGAAAAG GACGCTGCTC TTTCAACCCC AACGTGAACA CGGTGTCTGT TATGATCAAT 
GAGGAGCTTT TCTCTGGAAT GTATATAGAT TTCATGGGGA CAGATGCTGC TATTTTTCGA 
AGTTTAACCA AGAGGAATGC GGTCAGAACT GATCAACATA ATTCCAAATG GCTAAGTGAA 
CCTATGTTTG TAGATGCACA TGTCATCCCA GATGGTACTG ATCCAAATGA TGCTAAGGTG 
TACTTCTTCT TCAAAGAAAA ACTGACTGAC AATAACAGGA GCACGAAACA GATTCATTCC 
ATGATTGCTC GAATATGTCC TAATGACACT GGTGGACTGC GTAGCCTTGT CAACAAGTGG 
ACCACTTTCT TAAAGGCGAG GCTGGTGTGC TCGGTAACAG ATGAAGACGG CCCAGAAACA 
CACTTTGATG AATTAGAGGA TGTGTTTCTG CTGGAAACTG ATAACCCGAG GACAACACTA 
GTGTATGGCA TTTTTACAAC ATCAAGCTCA GTTTTCAAAG GATCAGCCGT GTGTGTGTAT 
CATTTATCTG ATATACAGAC TGTGTTTAAT GGGCCTTTTG CCCACAAAGA AGGGCCCAAT 
CATCAGCTGA TTTCCTATCA GGGCAGAATT CCATATCCTC GCCCTGGAAC TTGTCCAGGA 
GGAGCATTTA CACCCAATAT GCGAACCACC AAGGAGTTCC CAGATGATGT TGTCACTTTT 
ATTCGGAACC ATCCTCTCAT GTACAATTCC ATCTACCCAA TCCACAAAAG GCCTTTGATT 
GTTCGTATTG GCACTGACTA CAAGTATACA AAGATAGCTG TGGATCGAGT GAACGCTGCT 
GATGGGAGAT ACCATGTCCT GTTTCTCGGA ACAGATCGGG GTACTGTGCA AAAAGTGGTT 
GTTCTTCCTA CTAACAACTC TGTCAGTGGC GAGCTCATTC TGGAGGAGCT GGAAGTCTTT 
AAGAATCATG CTCCTATAAC AACAATGAAA ATTTCATCTA AAAAGCAACA GTTGTATGTG 
AGTTCCAATG AAGGGGTTTC CCAGGTATCT CTGCACCGCT GCCACATCTA TGGTACAGCC 
TGTGCTGACT GCTGCCTGGC GCGGGACCCT TATTGCGCCT GGGATGGCCA TTCCTGTTCC 
AGATTCTACC CAACTGGGAA ACGGAGGAGC CGAAGACAAG ATGTGAGACA TGGAAACCCA 
CTGACTCAAT GCAGAGGATT TAATCTAAAA GCATACAGAA ATGCAGCTGA AATTGTCCAG 
TATGGAGTAA AAAATAACAC CACTTTTCTG GAGTGTGCCC CCAAGTCTCC GCAGGCATCT 
ATCAAGTGGC TGTTACAGAA AGACAAAGAC AGGAGGAAAG AGGTTAAGCT GAATGAACGA 
ATAATAGCCA CTTCACAGGG ACTCCTGATC CGCTCTGTTC AGGGTTCTGA CCAAGGACTT 
TATCACTGCA TTGCTACAGA AAATAGTTTC AAGCAGACCA TAGCCAAGAT CAACTTCAAA 
GTTTTAGATT CAGAAATGGT GGCTGTTGTG ACGGACAAAT GGTCCCCATG GACCTGGGCC 
AGCTCTGTGA GGGCTTTACC CTTCCACCCG AAGGACATCA TGGGGGCATT CAGCCACTCA 
GAAATGCAGA TGATTAACCA ATATTGCAAA GACACTCGGC AGCAACATCA GCAGGGAGAT 
GAATCACAGA AAATGAGAGG GGACTATGGC AAGTTAAAGG CCCTCATCAA TAGTCGGAAA 
AGTAGAAACA GGAGGAATCA GTTGCCAGAG TCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006370.1
CDS	563..2818
Translation	MAFRTICVLVGVFICSICVKGSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINSRKSRNRRNQLPES

Target ORF information:

RefSeq Version	NM_006379.4
Organism	Homo sapiens(human)
Definition	Homo sapiens semaphorin 3C (SEMA3C), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006379.4

ORF Insert Sequence:

ATGGCATTCC GGACAATTTG CGTGTTGGTT GGAGTATTTA TTTGTTCTAT CTGTGTGAAA 
GGATCTTCCC AGCCCCAAGC AAGAGTTTAT TTAACATTTG ATGAACTTCG AGAAACCAAG 
ACCTCTGAAT ACTTCAGCCT TTCCCACCAT CCTTTAGACT ACAGGATTTT ATTAATGGAT 
GAAGATCAGG ACCGGATATA TGTGGGAAGC AAAGATCACA TTCTTTCCCT GAATATTAAC 
AATATAAGTC AAGAAGCTTT GAGTGTTTTC TGGCCAGCAT CTACAATCAA AGTTGAAGAA 
TGCAAAATGG CTGGCAAAGA TCCCACACAC GGCTGTGGGA ACTTTGTCCG TGTAATTCAG 
ACTTTCAATC GCACACATTT GTATGTCTGT GGGAGTGGCG CTTTCAGTCC TGTCTGTACT 
TACTTGAACA GAGGGAGGAG ATCAGAGGAC CAAGTTTTCA TGATTGACTC CAAGTGTGAA 
TCTGGAAAAG GACGCTGCTC TTTCAACCCC AACGTGAACA CGGTGTCTGT TATGATCAAT 
GAGGAGCTTT TCTCTGGAAT GTATATAGAT TTCATGGGGA CAGATGCTGC TATTTTTCGA 
AGTTTAACCA AGAGGAATGC GGTCAGAACT GATCAACATA ATTCCAAATG GCTAAGTGAA 
CCTATGTTTG TAGATGCACA TGTCATCCCA GATGGTACTG ATCCAAATGA TGCTAAGGTG 
TACTTCTTCT TCAAAGAAAA ACTGACTGAC AATAACAGGA GCACGAAACA GATTCATTCC 
ATGATTGCTC GAATATGTCC TAATGACACT GGTGGACTGC GTAGCCTTGT CAACAAGTGG 
ACCACTTTCT TAAAGGCGAG GCTGGTGTGC TCGGTAACAG ATGAAGACGG CCCAGAAACA 
CACTTTGATG AATTAGAGGA TGTGTTTCTG CTGGAAACTG ATAACCCGAG GACAACACTA 
GTGTATGGCA TTTTTACAAC ATCAAGCTCA GTTTTCAAAG GATCAGCCGT GTGTGTGTAT 
CATTTATCTG ATATACAGAC TGTGTTTAAT GGGCCTTTTG CCCACAAAGA AGGGCCCAAT 
CATCAGCTGA TTTCCTATCA GGGCAGAATT CCATATCCTC GCCCTGGAAC TTGTCCAGGA 
GGAGCATTTA CACCCAATAT GCGAACCACC AAGGAGTTCC CAGATGATGT TGTCACTTTT 
ATTCGGAACC ATCCTCTCAT GTACAATTCC ATCTACCCAA TCCACAAAAG GCCTTTGATT 
GTTCGTATTG GCACTGACTA CAAGTATACA AAGATAGCTG TGGATCGAGT GAACGCTGCT 
GATGGGAGAT ACCATGTCCT GTTTCTCGGA ACAGATCGGG GTACTGTGCA AAAAGTGGTT 
GTTCTTCCTA CTAACAACTC TGTCAGTGGC GAGCTCATTC TGGAGGAGCT GGAAGTCTTT 
AAGAATCATG CTCCTATAAC AACAATGAAA ATTTCATCTA AAAAGCAACA GTTGTATGTG 
AGTTCCAATG AAGGGGTTTC CCAGGTATCT CTGCACCGCT GCCACATCTA TGGTACAGCC 
TGTGCTGACT GCTGCCTGGC GCGGGACCCT TATTGCGCCT GGGATGGCCA TTCCTGTTCC 
AGATTCTACC CAACTGGGAA ACGGAGGAGC CGAAGACAAG ATGTGAGACA TGGAAACCCA 
CTGACTCAAT GCAGAGGATT TAATCTAAAA GCATACAGAA ATGCAGCTGA AATTGTCCAG 
TATGGAGTAA AAAATAACAC CACTTTTCTG GAGTGTGCCC CCAAGTCTCC GCAGGCATCT 
ATCAAGTGGC TGTTACAGAA AGACAAAGAC AGGAGGAAAG AGGTTAAGCT GAATGAACGA 
ATAATAGCCA CTTCACAGGG ACTCCTGATC CGCTCTGTTC AGGGTTCTGA CCAAGGACTT 
TATCACTGCA TTGCTACAGA AAATAGTTTC AAGCAGACCA TAGCCAAGAT CAACTTCAAA 
GTTTTAGATT CAGAAATGGT GGCTGTTGTG ACGGACAAAT GGTCCCCATG GACCTGGGCC 
AGCTCTGTGA GGGCTTTACC CTTCCACCCG AAGGACATCA TGGGGGCATT CAGCCACTCA 
GAAATGCAGA TGATTAACCA ATATTGCAAA GACACTCGGC AGCAACATCA GCAGGGAGAT 
GAATCACAGA AAATGAGAGG GGACTATGGC AAGTTAAAGG CCCTCATCAA TAGTCGGAAA 
AGTAGAAACA GGAGGAATCA GTTGCCAGAG TCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEMA3C ( NM_006379.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_006370.1 Homo sapiens semaphorin 3C (SEMA3C), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu05543
Clone ID Related Accession (Same CDS sequence)	NM_006379.4 , NM_006379.5 , NM_006379.3
Accession Version	NM_006379.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2256bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	semaphorin-3C isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB000220.1, AK304294.1, BC030690.1, CN334969.1, CN334967.1, AA853650.1 and BM473251.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_006379.4. Transcript Variant: This variant (2) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC030690.1, AB000220.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265361.8/ ENSP00000265361.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCATTCC GGACAATTTG CGTGTTGGTT GGAGTATTTA TTTGTTCTAT CTGTGTGAAA 
GGATCTTCCC AGCCCCAAGC AAGAGTTTAT TTAACATTTG ATGAACTTCG AGAAACCAAG 
ACCTCTGAAT ACTTCAGCCT TTCCCACCAT CCTTTAGACT ACAGGATTTT ATTAATGGAT 
GAAGATCAGG ACCGGATATA TGTGGGAAGC AAAGATCACA TTCTTTCCCT GAATATTAAC 
AATATAAGTC AAGAAGCTTT GAGTGTTTTC TGGCCAGCAT CTACAATCAA AGTTGAAGAA 
TGCAAAATGG CTGGCAAAGA TCCCACACAC GGCTGTGGGA ACTTTGTCCG TGTAATTCAG 
ACTTTCAATC GCACACATTT GTATGTCTGT GGGAGTGGCG CTTTCAGTCC TGTCTGTACT 
TACTTGAACA GAGGGAGGAG ATCAGAGGAC CAAGTTTTCA TGATTGACTC CAAGTGTGAA 
TCTGGAAAAG GACGCTGCTC TTTCAACCCC AACGTGAACA CGGTGTCTGT TATGATCAAT 
GAGGAGCTTT TCTCTGGAAT GTATATAGAT TTCATGGGGA CAGATGCTGC TATTTTTCGA 
AGTTTAACCA AGAGGAATGC GGTCAGAACT GATCAACATA ATTCCAAATG GCTAAGTGAA 
CCTATGTTTG TAGATGCACA TGTCATCCCA GATGGTACTG ATCCAAATGA TGCTAAGGTG 
TACTTCTTCT TCAAAGAAAA ACTGACTGAC AATAACAGGA GCACGAAACA GATTCATTCC 
ATGATTGCTC GAATATGTCC TAATGACACT GGTGGACTGC GTAGCCTTGT CAACAAGTGG 
ACCACTTTCT TAAAGGCGAG GCTGGTGTGC TCGGTAACAG ATGAAGACGG CCCAGAAACA 
CACTTTGATG AATTAGAGGA TGTGTTTCTG CTGGAAACTG ATAACCCGAG GACAACACTA 
GTGTATGGCA TTTTTACAAC ATCAAGCTCA GTTTTCAAAG GATCAGCCGT GTGTGTGTAT 
CATTTATCTG ATATACAGAC TGTGTTTAAT GGGCCTTTTG CCCACAAAGA AGGGCCCAAT 
CATCAGCTGA TTTCCTATCA GGGCAGAATT CCATATCCTC GCCCTGGAAC TTGTCCAGGA 
GGAGCATTTA CACCCAATAT GCGAACCACC AAGGAGTTCC CAGATGATGT TGTCACTTTT 
ATTCGGAACC ATCCTCTCAT GTACAATTCC ATCTACCCAA TCCACAAAAG GCCTTTGATT 
GTTCGTATTG GCACTGACTA CAAGTATACA AAGATAGCTG TGGATCGAGT GAACGCTGCT 
GATGGGAGAT ACCATGTCCT GTTTCTCGGA ACAGATCGGG GTACTGTGCA AAAAGTGGTT 
GTTCTTCCTA CTAACAACTC TGTCAGTGGC GAGCTCATTC TGGAGGAGCT GGAAGTCTTT 
AAGAATCATG CTCCTATAAC AACAATGAAA ATTTCATCTA AAAAGCAACA GTTGTATGTG 
AGTTCCAATG AAGGGGTTTC CCAGGTATCT CTGCACCGCT GCCACATCTA TGGTACAGCC 
TGTGCTGACT GCTGCCTGGC GCGGGACCCT TATTGCGCCT GGGATGGCCA TTCCTGTTCC 
AGATTCTACC CAACTGGGAA ACGGAGGAGC CGAAGACAAG ATGTGAGACA TGGAAACCCA 
CTGACTCAAT GCAGAGGATT TAATCTAAAA GCATACAGAA ATGCAGCTGA AATTGTCCAG 
TATGGAGTAA AAAATAACAC CACTTTTCTG GAGTGTGCCC CCAAGTCTCC GCAGGCATCT 
ATCAAGTGGC TGTTACAGAA AGACAAAGAC AGGAGGAAAG AGGTTAAGCT GAATGAACGA 
ATAATAGCCA CTTCACAGGG ACTCCTGATC CGCTCTGTTC AGGGTTCTGA CCAAGGACTT 
TATCACTGCA TTGCTACAGA AAATAGTTTC AAGCAGACCA TAGCCAAGAT CAACTTCAAA 
GTTTTAGATT CAGAAATGGT GGCTGTTGTG ACGGACAAAT GGTCCCCATG GACCTGGGCC 
AGCTCTGTGA GGGCTTTACC CTTCCACCCG AAGGACATCA TGGGGGCATT CAGCCACTCA 
GAAATGCAGA TGATTAACCA ATATTGCAAA GACACTCGGC AGCAACATCA GCAGGGAGAT 
GAATCACAGA AAATGAGAGG GGACTATGGC AAGTTAAAGG CCCTCATCAA TAGTCGGAAA 
AGTAGAAACA GGAGGAATCA GTTGCCAGAG TCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006370.1
CDS	263..2518
Translation	MAFRTICVLVGVFICSICVKGSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINSRKSRNRRNQLPES

Target ORF information:

RefSeq Version	NM_006379.5
Organism	Homo sapiens(human)
Definition	Homo sapiens semaphorin 3C (SEMA3C), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006379.5

ORF Insert Sequence:

ATGGCATTCC GGACAATTTG CGTGTTGGTT GGAGTATTTA TTTGTTCTAT CTGTGTGAAA 
GGATCTTCCC AGCCCCAAGC AAGAGTTTAT TTAACATTTG ATGAACTTCG AGAAACCAAG 
ACCTCTGAAT ACTTCAGCCT TTCCCACCAT CCTTTAGACT ACAGGATTTT ATTAATGGAT 
GAAGATCAGG ACCGGATATA TGTGGGAAGC AAAGATCACA TTCTTTCCCT GAATATTAAC 
AATATAAGTC AAGAAGCTTT GAGTGTTTTC TGGCCAGCAT CTACAATCAA AGTTGAAGAA 
TGCAAAATGG CTGGCAAAGA TCCCACACAC GGCTGTGGGA ACTTTGTCCG TGTAATTCAG 
ACTTTCAATC GCACACATTT GTATGTCTGT GGGAGTGGCG CTTTCAGTCC TGTCTGTACT 
TACTTGAACA GAGGGAGGAG ATCAGAGGAC CAAGTTTTCA TGATTGACTC CAAGTGTGAA 
TCTGGAAAAG GACGCTGCTC TTTCAACCCC AACGTGAACA CGGTGTCTGT TATGATCAAT 
GAGGAGCTTT TCTCTGGAAT GTATATAGAT TTCATGGGGA CAGATGCTGC TATTTTTCGA 
AGTTTAACCA AGAGGAATGC GGTCAGAACT GATCAACATA ATTCCAAATG GCTAAGTGAA 
CCTATGTTTG TAGATGCACA TGTCATCCCA GATGGTACTG ATCCAAATGA TGCTAAGGTG 
TACTTCTTCT TCAAAGAAAA ACTGACTGAC AATAACAGGA GCACGAAACA GATTCATTCC 
ATGATTGCTC GAATATGTCC TAATGACACT GGTGGACTGC GTAGCCTTGT CAACAAGTGG 
ACCACTTTCT TAAAGGCGAG GCTGGTGTGC TCGGTAACAG ATGAAGACGG CCCAGAAACA 
CACTTTGATG AATTAGAGGA TGTGTTTCTG CTGGAAACTG ATAACCCGAG GACAACACTA 
GTGTATGGCA TTTTTACAAC ATCAAGCTCA GTTTTCAAAG GATCAGCCGT GTGTGTGTAT 
CATTTATCTG ATATACAGAC TGTGTTTAAT GGGCCTTTTG CCCACAAAGA AGGGCCCAAT 
CATCAGCTGA TTTCCTATCA GGGCAGAATT CCATATCCTC GCCCTGGAAC TTGTCCAGGA 
GGAGCATTTA CACCCAATAT GCGAACCACC AAGGAGTTCC CAGATGATGT TGTCACTTTT 
ATTCGGAACC ATCCTCTCAT GTACAATTCC ATCTACCCAA TCCACAAAAG GCCTTTGATT 
GTTCGTATTG GCACTGACTA CAAGTATACA AAGATAGCTG TGGATCGAGT GAACGCTGCT 
GATGGGAGAT ACCATGTCCT GTTTCTCGGA ACAGATCGGG GTACTGTGCA AAAAGTGGTT 
GTTCTTCCTA CTAACAACTC TGTCAGTGGC GAGCTCATTC TGGAGGAGCT GGAAGTCTTT 
AAGAATCATG CTCCTATAAC AACAATGAAA ATTTCATCTA AAAAGCAACA GTTGTATGTG 
AGTTCCAATG AAGGGGTTTC CCAGGTATCT CTGCACCGCT GCCACATCTA TGGTACAGCC 
TGTGCTGACT GCTGCCTGGC GCGGGACCCT TATTGCGCCT GGGATGGCCA TTCCTGTTCC 
AGATTCTACC CAACTGGGAA ACGGAGGAGC CGAAGACAAG ATGTGAGACA TGGAAACCCA 
CTGACTCAAT GCAGAGGATT TAATCTAAAA GCATACAGAA ATGCAGCTGA AATTGTCCAG 
TATGGAGTAA AAAATAACAC CACTTTTCTG GAGTGTGCCC CCAAGTCTCC GCAGGCATCT 
ATCAAGTGGC TGTTACAGAA AGACAAAGAC AGGAGGAAAG AGGTTAAGCT GAATGAACGA 
ATAATAGCCA CTTCACAGGG ACTCCTGATC CGCTCTGTTC AGGGTTCTGA CCAAGGACTT 
TATCACTGCA TTGCTACAGA AAATAGTTTC AAGCAGACCA TAGCCAAGAT CAACTTCAAA 
GTTTTAGATT CAGAAATGGT GGCTGTTGTG ACGGACAAAT GGTCCCCATG GACCTGGGCC 
AGCTCTGTGA GGGCTTTACC CTTCCACCCG AAGGACATCA TGGGGGCATT CAGCCACTCA 
GAAATGCAGA TGATTAACCA ATATTGCAAA GACACTCGGC AGCAACATCA GCAGGGAGAT 
GAATCACAGA AAATGAGAGG GGACTATGGC AAGTTAAAGG CCCTCATCAA TAGTCGGAAA 
AGTAGAAACA GGAGGAATCA GTTGCCAGAG TCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEMA3C ( NM_006379.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006370.1 Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (SEMA3C), mRNA.

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CloneID	OHu05543
Clone ID Related Accession (Same CDS sequence)	NM_006379.4 , NM_006379.5 , NM_006379.3
Accession Version	NM_006379.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2256bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	semaphorin-3C precursor
Comment

ATGGCATTCC GGACAATTTG CGTGTTGGTT GGAGTATTTA TTTGTTCTAT CTGTGTGAAA 
GGATCTTCCC AGCCCCAAGC AAGAGTTTAT TTAACATTTG ATGAACTTCG AGAAACCAAG 
ACCTCTGAAT ACTTCAGCCT TTCCCACCAT CCTTTAGACT ACAGGATTTT ATTAATGGAT 
GAAGATCAGG ACCGGATATA TGTGGGAAGC AAAGATCACA TTCTTTCCCT GAATATTAAC 
AATATAAGTC AAGAAGCTTT GAGTGTTTTC TGGCCAGCAT CTACAATCAA AGTTGAAGAA 
TGCAAAATGG CTGGCAAAGA TCCCACACAC GGCTGTGGGA ACTTTGTCCG TGTAATTCAG 
ACTTTCAATC GCACACATTT GTATGTCTGT GGGAGTGGCG CTTTCAGTCC TGTCTGTACT 
TACTTGAACA GAGGGAGGAG ATCAGAGGAC CAAGTTTTCA TGATTGACTC CAAGTGTGAA 
TCTGGAAAAG GACGCTGCTC TTTCAACCCC AACGTGAACA CGGTGTCTGT TATGATCAAT 
GAGGAGCTTT TCTCTGGAAT GTATATAGAT TTCATGGGGA CAGATGCTGC TATTTTTCGA 
AGTTTAACCA AGAGGAATGC GGTCAGAACT GATCAACATA ATTCCAAATG GCTAAGTGAA 
CCTATGTTTG TAGATGCACA TGTCATCCCA GATGGTACTG ATCCAAATGA TGCTAAGGTG 
TACTTCTTCT TCAAAGAAAA ACTGACTGAC AATAACAGGA GCACGAAACA GATTCATTCC 
ATGATTGCTC GAATATGTCC TAATGACACT GGTGGACTGC GTAGCCTTGT CAACAAGTGG 
ACCACTTTCT TAAAGGCGAG GCTGGTGTGC TCGGTAACAG ATGAAGACGG CCCAGAAACA 
CACTTTGATG AATTAGAGGA TGTGTTTCTG CTGGAAACTG ATAACCCGAG GACAACACTA 
GTGTATGGCA TTTTTACAAC ATCAAGCTCA GTTTTCAAAG GATCAGCCGT GTGTGTGTAT 
CATTTATCTG ATATACAGAC TGTGTTTAAT GGGCCTTTTG CCCACAAAGA AGGGCCCAAT 
CATCAGCTGA TTTCCTATCA GGGCAGAATT CCATATCCTC GCCCTGGAAC TTGTCCAGGA 
GGAGCATTTA CACCCAATAT GCGAACCACC AAGGAGTTCC CAGATGATGT TGTCACTTTT 
ATTCGGAACC ATCCTCTCAT GTACAATTCC ATCTACCCAA TCCACAAAAG GCCTTTGATT 
GTTCGTATTG GCACTGACTA CAAGTATACA AAGATAGCTG TGGATCGAGT GAACGCTGCT 
GATGGGAGAT ACCATGTCCT GTTTCTCGGA ACAGATCGGG GTACTGTGCA AAAAGTGGTT 
GTTCTTCCTA CTAACAACTC TGTCAGTGGC GAGCTCATTC TGGAGGAGCT GGAAGTCTTT 
AAGAATCATG CTCCTATAAC AACAATGAAA ATTTCATCTA AAAAGCAACA GTTGTATGTG 
AGTTCCAATG AAGGGGTTTC CCAGGTATCT CTGCACCGCT GCCACATCTA TGGTACAGCC 
TGTGCTGACT GCTGCCTGGC GCGGGACCCT TATTGCGCCT GGGATGGCCA TTCCTGTTCC 
AGATTCTACC CAACTGGGAA ACGGAGGAGC CGAAGACAAG ATGTGAGACA TGGAAACCCA 
CTGACTCAAT GCAGAGGATT TAATCTAAAA GCATACAGAA ATGCAGCTGA AATTGTCCAG 
TATGGAGTAA AAAATAACAC CACTTTTCTG GAGTGTGCCC CCAAGTCTCC GCAGGCATCT 
ATCAAGTGGC TGTTACAGAA AGACAAAGAC AGGAGGAAAG AGGTTAAGCT GAATGAACGA 
ATAATAGCCA CTTCACAGGG ACTCCTGATC CGCTCTGTTC AGGGTTCTGA CCAAGGACTT 
TATCACTGCA TTGCTACAGA AAATAGTTTC AAGCAGACCA TAGCCAAGAT CAACTTCAAA 
GTTTTAGATT CAGAAATGGT GGCTGTTGTG ACGGACAAAT GGTCCCCATG GACCTGGGCC 
AGCTCTGTGA GGGCTTTACC CTTCCACCCG AAGGACATCA TGGGGGCATT CAGCCACTCA 
GAAATGCAGA TGATTAACCA ATATTGCAAA GACACTCGGC AGCAACATCA GCAGGGAGAT 
GAATCACAGA AAATGAGAGG GGACTATGGC AAGTTAAAGG CCCTCATCAA TAGTCGGAAA 
AGTAGAAACA GGAGGAATCA GTTGCCAGAG TCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_006370.1

Translation

MAFRTICVLVGVFICSICVKGSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINSRKSRNRRNQLPES

Target ORF information:

RefSeq Version	NM_006379.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (SEMA3C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006379.3

ORF Insert Sequence:

ATGGCATTCC GGACAATTTG CGTGTTGGTT GGAGTATTTA TTTGTTCTAT CTGTGTGAAA 
GGATCTTCCC AGCCCCAAGC AAGAGTTTAT TTAACATTTG ATGAACTTCG AGAAACCAAG 
ACCTCTGAAT ACTTCAGCCT TTCCCACCAT CCTTTAGACT ACAGGATTTT ATTAATGGAT 
GAAGATCAGG ACCGGATATA TGTGGGAAGC AAAGATCACA TTCTTTCCCT GAATATTAAC 
AATATAAGTC AAGAAGCTTT GAGTGTTTTC TGGCCAGCAT CTACAATCAA AGTTGAAGAA 
TGCAAAATGG CTGGCAAAGA TCCCACACAC GGCTGTGGGA ACTTTGTCCG TGTAATTCAG 
ACTTTCAATC GCACACATTT GTATGTCTGT GGGAGTGGCG CTTTCAGTCC TGTCTGTACT 
TACTTGAACA GAGGGAGGAG ATCAGAGGAC CAAGTTTTCA TGATTGACTC CAAGTGTGAA 
TCTGGAAAAG GACGCTGCTC TTTCAACCCC AACGTGAACA CGGTGTCTGT TATGATCAAT 
GAGGAGCTTT TCTCTGGAAT GTATATAGAT TTCATGGGGA CAGATGCTGC TATTTTTCGA 
AGTTTAACCA AGAGGAATGC GGTCAGAACT GATCAACATA ATTCCAAATG GCTAAGTGAA 
CCTATGTTTG TAGATGCACA TGTCATCCCA GATGGTACTG ATCCAAATGA TGCTAAGGTG 
TACTTCTTCT TCAAAGAAAA ACTGACTGAC AATAACAGGA GCACGAAACA GATTCATTCC 
ATGATTGCTC GAATATGTCC TAATGACACT GGTGGACTGC GTAGCCTTGT CAACAAGTGG 
ACCACTTTCT TAAAGGCGAG GCTGGTGTGC TCGGTAACAG ATGAAGACGG CCCAGAAACA 
CACTTTGATG AATTAGAGGA TGTGTTTCTG CTGGAAACTG ATAACCCGAG GACAACACTA 
GTGTATGGCA TTTTTACAAC ATCAAGCTCA GTTTTCAAAG GATCAGCCGT GTGTGTGTAT 
CATTTATCTG ATATACAGAC TGTGTTTAAT GGGCCTTTTG CCCACAAAGA AGGGCCCAAT 
CATCAGCTGA TTTCCTATCA GGGCAGAATT CCATATCCTC GCCCTGGAAC TTGTCCAGGA 
GGAGCATTTA CACCCAATAT GCGAACCACC AAGGAGTTCC CAGATGATGT TGTCACTTTT 
ATTCGGAACC ATCCTCTCAT GTACAATTCC ATCTACCCAA TCCACAAAAG GCCTTTGATT 
GTTCGTATTG GCACTGACTA CAAGTATACA AAGATAGCTG TGGATCGAGT GAACGCTGCT 
GATGGGAGAT ACCATGTCCT GTTTCTCGGA ACAGATCGGG GTACTGTGCA AAAAGTGGTT 
GTTCTTCCTA CTAACAACTC TGTCAGTGGC GAGCTCATTC TGGAGGAGCT GGAAGTCTTT 
AAGAATCATG CTCCTATAAC AACAATGAAA ATTTCATCTA AAAAGCAACA GTTGTATGTG 
AGTTCCAATG AAGGGGTTTC CCAGGTATCT CTGCACCGCT GCCACATCTA TGGTACAGCC 
TGTGCTGACT GCTGCCTGGC GCGGGACCCT TATTGCGCCT GGGATGGCCA TTCCTGTTCC 
AGATTCTACC CAACTGGGAA ACGGAGGAGC CGAAGACAAG ATGTGAGACA TGGAAACCCA 
CTGACTCAAT GCAGAGGATT TAATCTAAAA GCATACAGAA ATGCAGCTGA AATTGTCCAG 
TATGGAGTAA AAAATAACAC CACTTTTCTG GAGTGTGCCC CCAAGTCTCC GCAGGCATCT 
ATCAAGTGGC TGTTACAGAA AGACAAAGAC AGGAGGAAAG AGGTTAAGCT GAATGAACGA 
ATAATAGCCA CTTCACAGGG ACTCCTGATC CGCTCTGTTC AGGGTTCTGA CCAAGGACTT 
TATCACTGCA TTGCTACAGA AAATAGTTTC AAGCAGACCA TAGCCAAGAT CAACTTCAAA 
GTTTTAGATT CAGAAATGGT GGCTGTTGTG ACGGACAAAT GGTCCCCATG GACCTGGGCC 
AGCTCTGTGA GGGCTTTACC CTTCCACCCG AAGGACATCA TGGGGGCATT CAGCCACTCA 
GAAATGCAGA TGATTAACCA ATATTGCAAA GACACTCGGC AGCAACATCA GCAGGGAGAT 
GAATCACAGA AAATGAGAGG GGACTATGGC AAGTTAAAGG CCCTCATCAA TAGTCGGAAA 
AGTAGAAACA GGAGGAATCA GTTGCCAGAG TCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEMA3C ( NM_001350121.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001337050.1 Homo sapiens semaphorin 3C (SEMA3C), transcript variant 3, mRNA.

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CloneID	OHu41339
Clone ID Related Accession (Same CDS sequence)	NM_001350121.1 , XM_005250113.2
Accession Version	NM_001350121.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2082bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	semaphorin-3C isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC004880.1, AB000220.1, AC093683.3, AC073850.4 and AI491966.1. Transcript Variant: This variant (3) differs in the 5' UTR and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.272448.1, SRR1803613.190258.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATGAAG ATCAGGACCG GATATATGTG GGAAGCAAAG ATCACATTCT TTCCCTGAAT 
ATTAACAATA TAAGTCAAGA AGCTTTGAGT GTTTTCTGGC CAGCATCTAC AATCAAAGTT 
GAAGAATGCA AAATGGCTGG CAAAGATCCC ACACACGGCT GTGGGAACTT TGTCCGTGTA 
ATTCAGACTT TCAATCGCAC ACATTTGTAT GTCTGTGGGA GTGGCGCTTT CAGTCCTGTC 
TGTACTTACT TGAACAGAGG GAGGAGATCA GAGGACCAAG TTTTCATGAT TGACTCCAAG 
TGTGAATCTG GAAAAGGACG CTGCTCTTTC AACCCCAACG TGAACACGGT GTCTGTTATG 
ATCAATGAGG AGCTTTTCTC TGGAATGTAT ATAGATTTCA TGGGGACAGA TGCTGCTATT 
TTTCGAAGTT TAACCAAGAG GAATGCGGTC AGAACTGATC AACATAATTC CAAATGGCTA 
AGTGAACCTA TGTTTGTAGA TGCACATGTC ATCCCAGATG GTACTGATCC AAATGATGCT 
AAGGTGTACT TCTTCTTCAA AGAAAAACTG ACTGACAATA ACAGGAGCAC GAAACAGATT 
CATTCCATGA TTGCTCGAAT ATGTCCTAAT GACACTGGTG GACTGCGTAG CCTTGTCAAC 
AAGTGGACCA CTTTCTTAAA GGCGAGGCTG GTGTGCTCGG TAACAGATGA AGACGGCCCA 
GAAACACACT TTGATGAATT AGAGGATGTG TTTCTGCTGG AAACTGATAA CCCGAGGACA 
ACACTAGTGT ATGGCATTTT TACAACATCA AGCTCAGTTT TCAAAGGATC AGCCGTGTGT 
GTGTATCATT TATCTGATAT ACAGACTGTG TTTAATGGGC CTTTTGCCCA CAAAGAAGGG 
CCCAATCATC AGCTGATTTC CTATCAGGGC AGAATTCCAT ATCCTCGCCC TGGAACTTGT 
CCAGGAGGAG CATTTACACC CAATATGCGA ACCACCAAGG AGTTCCCAGA TGATGTTGTC 
ACTTTTATTC GGAACCATCC TCTCATGTAC AATTCCATCT ACCCAATCCA CAAAAGGCCT 
TTGATTGTTC GTATTGGCAC TGACTACAAG TATACAAAGA TAGCTGTGGA TCGAGTGAAC 
GCTGCTGATG GGAGATACCA TGTCCTGTTT CTCGGAACAG ATCGGGGTAC TGTGCAAAAA 
GTGGTTGTTC TTCCTACTAA CAACTCTGTC AGTGGCGAGC TCATTCTGGA GGAGCTGGAA 
GTCTTTAAGA ATCATGCTCC TATAACAACA ATGAAAATTT CATCTAAAAA GCAACAGTTG 
TATGTGAGTT CCAATGAAGG GGTTTCCCAG GTATCTCTGC ACCGCTGCCA CATCTATGGT 
ACAGCCTGTG CTGACTGCTG CCTGGCGCGG GACCCTTATT GCGCCTGGGA TGGCCATTCC 
TGTTCCAGAT TCTACCCAAC TGGGAAACGG AGGAGCCGAA GACAAGATGT GAGACATGGA 
AACCCACTGA CTCAATGCAG AGGATTTAAT CTAAAAGCAT ACAGAAATGC AGCTGAAATT 
GTCCAGTATG GAGTAAAAAA TAACACCACT TTTCTGGAGT GTGCCCCCAA GTCTCCGCAG 
GCATCTATCA AGTGGCTGTT ACAGAAAGAC AAAGACAGGA GGAAAGAGGT TAAGCTGAAT 
GAACGAATAA TAGCCACTTC ACAGGGACTC CTGATCCGCT CTGTTCAGGG TTCTGACCAA 
GGACTTTATC ACTGCATTGC TACAGAAAAT AGTTTCAAGC AGACCATAGC CAAGATCAAC 
TTCAAAGTTT TAGATTCAGA AATGGTGGCT GTTGTGACGG ACAAATGGTC CCCATGGACC 
TGGGCCAGCT CTGTGAGGGC TTTACCCTTC CACCCGAAGG ACATCATGGG GGCATTCAGC 
CACTCAGAAA TGCAGATGAT TAACCAATAT TGCAAAGACA CTCGGCAGCA ACATCAGCAG 
GGAGATGAAT CACAGAAAAT GAGAGGGGAC TATGGCAAGT TAAAGGCCCT CATCAATAGT 
CGGAAAAGTA GAAACAGGAG GAATCAGTTG CCAGAGTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001337050.1
CDS	825..2906
Translation	MDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINSRKSRNRRNQLPES

Target ORF information:

RefSeq Version	NM_001350121.1
Organism	Homo sapiens(human)
Definition	Homo sapiens semaphorin 3C (SEMA3C), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001350121.1

ORF Insert Sequence:

ATGGATGAAG ATCAGGACCG GATATATGTG GGAAGCAAAG ATCACATTCT TTCCCTGAAT 
ATTAACAATA TAAGTCAAGA AGCTTTGAGT GTTTTCTGGC CAGCATCTAC AATCAAAGTT 
GAAGAATGCA AAATGGCTGG CAAAGATCCC ACACACGGCT GTGGGAACTT TGTCCGTGTA 
ATTCAGACTT TCAATCGCAC ACATTTGTAT GTCTGTGGGA GTGGCGCTTT CAGTCCTGTC 
TGTACTTACT TGAACAGAGG GAGGAGATCA GAGGACCAAG TTTTCATGAT TGACTCCAAG 
TGTGAATCTG GAAAAGGACG CTGCTCTTTC AACCCCAACG TGAACACGGT GTCTGTTATG 
ATCAATGAGG AGCTTTTCTC TGGAATGTAT ATAGATTTCA TGGGGACAGA TGCTGCTATT 
TTTCGAAGTT TAACCAAGAG GAATGCGGTC AGAACTGATC AACATAATTC CAAATGGCTA 
AGTGAACCTA TGTTTGTAGA TGCACATGTC ATCCCAGATG GTACTGATCC AAATGATGCT 
AAGGTGTACT TCTTCTTCAA AGAAAAACTG ACTGACAATA ACAGGAGCAC GAAACAGATT 
CATTCCATGA TTGCTCGAAT ATGTCCTAAT GACACTGGTG GACTGCGTAG CCTTGTCAAC 
AAGTGGACCA CTTTCTTAAA GGCGAGGCTG GTGTGCTCGG TAACAGATGA AGACGGCCCA 
GAAACACACT TTGATGAATT AGAGGATGTG TTTCTGCTGG AAACTGATAA CCCGAGGACA 
ACACTAGTGT ATGGCATTTT TACAACATCA AGCTCAGTTT TCAAAGGATC AGCCGTGTGT 
GTGTATCATT TATCTGATAT ACAGACTGTG TTTAATGGGC CTTTTGCCCA CAAAGAAGGG 
CCCAATCATC AGCTGATTTC CTATCAGGGC AGAATTCCAT ATCCTCGCCC TGGAACTTGT 
CCAGGAGGAG CATTTACACC CAATATGCGA ACCACCAAGG AGTTCCCAGA TGATGTTGTC 
ACTTTTATTC GGAACCATCC TCTCATGTAC AATTCCATCT ACCCAATCCA CAAAAGGCCT 
TTGATTGTTC GTATTGGCAC TGACTACAAG TATACAAAGA TAGCTGTGGA TCGAGTGAAC 
GCTGCTGATG GGAGATACCA TGTCCTGTTT CTCGGAACAG ATCGGGGTAC TGTGCAAAAA 
GTGGTTGTTC TTCCTACTAA CAACTCTGTC AGTGGCGAGC TCATTCTGGA GGAGCTGGAA 
GTCTTTAAGA ATCATGCTCC TATAACAACA ATGAAAATTT CATCTAAAAA GCAACAGTTG 
TATGTGAGTT CCAATGAAGG GGTTTCCCAG GTATCTCTGC ACCGCTGCCA CATCTATGGT 
ACAGCCTGTG CTGACTGCTG CCTGGCGCGG GACCCTTATT GCGCCTGGGA TGGCCATTCC 
TGTTCCAGAT TCTACCCAAC TGGGAAACGG AGGAGCCGAA GACAAGATGT GAGACATGGA 
AACCCACTGA CTCAATGCAG AGGATTTAAT CTAAAAGCAT ACAGAAATGC AGCTGAAATT 
GTCCAGTATG GAGTAAAAAA TAACACCACT TTTCTGGAGT GTGCCCCCAA GTCTCCGCAG 
GCATCTATCA AGTGGCTGTT ACAGAAAGAC AAAGACAGGA GGAAAGAGGT TAAGCTGAAT 
GAACGAATAA TAGCCACTTC ACAGGGACTC CTGATCCGCT CTGTTCAGGG TTCTGACCAA 
GGACTTTATC ACTGCATTGC TACAGAAAAT AGTTTCAAGC AGACCATAGC CAAGATCAAC 
TTCAAAGTTT TAGATTCAGA AATGGTGGCT GTTGTGACGG ACAAATGGTC CCCATGGACC 
TGGGCCAGCT CTGTGAGGGC TTTACCCTTC CACCCGAAGG ACATCATGGG GGCATTCAGC 
CACTCAGAAA TGCAGATGAT TAACCAATAT TGCAAAGACA CTCGGCAGCA ACATCAGCAG 
GGAGATGAAT CACAGAAAAT GAGAGGGGAC TATGGCAAGT TAAAGGCCCT CATCAATAGT 
CGGAAAAGTA GAAACAGGAG GAATCAGTTG CCAGAGTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEMA3C ( XM_005250113.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005250170.1 Homo sapiens semaphorin 3C (SEMA3C), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu41339
Clone ID Related Accession (Same CDS sequence)	NM_001350121.1 , XM_005250113.2
Accession Version	XM_005250113.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2082bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	semaphorin-3C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005250113.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGAAG ATCAGGACCG GATATATGTG GGAAGCAAAG ATCACATTCT TTCCCTGAAT 
ATTAACAATA TAAGTCAAGA AGCTTTGAGT GTTTTCTGGC CAGCATCTAC AATCAAAGTT 
GAAGAATGCA AAATGGCTGG CAAAGATCCC ACACACGGCT GTGGGAACTT TGTCCGTGTA 
ATTCAGACTT TCAATCGCAC ACATTTGTAT GTCTGTGGGA GTGGCGCTTT CAGTCCTGTC 
TGTACTTACT TGAACAGAGG GAGGAGATCA GAGGACCAAG TTTTCATGAT TGACTCCAAG 
TGTGAATCTG GAAAAGGACG CTGCTCTTTC AACCCCAACG TGAACACGGT GTCTGTTATG 
ATCAATGAGG AGCTTTTCTC TGGAATGTAT ATAGATTTCA TGGGGACAGA TGCTGCTATT 
TTTCGAAGTT TAACCAAGAG GAATGCGGTC AGAACTGATC AACATAATTC CAAATGGCTA 
AGTGAACCTA TGTTTGTAGA TGCACATGTC ATCCCAGATG GTACTGATCC AAATGATGCT 
AAGGTGTACT TCTTCTTCAA AGAAAAACTG ACTGACAATA ACAGGAGCAC GAAACAGATT 
CATTCCATGA TTGCTCGAAT ATGTCCTAAT GACACTGGTG GACTGCGTAG CCTTGTCAAC 
AAGTGGACCA CTTTCTTAAA GGCGAGGCTG GTGTGCTCGG TAACAGATGA AGACGGCCCA 
GAAACACACT TTGATGAATT AGAGGATGTG TTTCTGCTGG AAACTGATAA CCCGAGGACA 
ACACTAGTGT ATGGCATTTT TACAACATCA AGCTCAGTTT TCAAAGGATC AGCCGTGTGT 
GTGTATCATT TATCTGATAT ACAGACTGTG TTTAATGGGC CTTTTGCCCA CAAAGAAGGG 
CCCAATCATC AGCTGATTTC CTATCAGGGC AGAATTCCAT ATCCTCGCCC TGGAACTTGT 
CCAGGAGGAG CATTTACACC CAATATGCGA ACCACCAAGG AGTTCCCAGA TGATGTTGTC 
ACTTTTATTC GGAACCATCC TCTCATGTAC AATTCCATCT ACCCAATCCA CAAAAGGCCT 
TTGATTGTTC GTATTGGCAC TGACTACAAG TATACAAAGA TAGCTGTGGA TCGAGTGAAC 
GCTGCTGATG GGAGATACCA TGTCCTGTTT CTCGGAACAG ATCGGGGTAC TGTGCAAAAA 
GTGGTTGTTC TTCCTACTAA CAACTCTGTC AGTGGCGAGC TCATTCTGGA GGAGCTGGAA 
GTCTTTAAGA ATCATGCTCC TATAACAACA ATGAAAATTT CATCTAAAAA GCAACAGTTG 
TATGTGAGTT CCAATGAAGG GGTTTCCCAG GTATCTCTGC ACCGCTGCCA CATCTATGGT 
ACAGCCTGTG CTGACTGCTG CCTGGCGCGG GACCCTTATT GCGCCTGGGA TGGCCATTCC 
TGTTCCAGAT TCTACCCAAC TGGGAAACGG AGGAGCCGAA GACAAGATGT GAGACATGGA 
AACCCACTGA CTCAATGCAG AGGATTTAAT CTAAAAGCAT ACAGAAATGC AGCTGAAATT 
GTCCAGTATG GAGTAAAAAA TAACACCACT TTTCTGGAGT GTGCCCCCAA GTCTCCGCAG 
GCATCTATCA AGTGGCTGTT ACAGAAAGAC AAAGACAGGA GGAAAGAGGT TAAGCTGAAT 
GAACGAATAA TAGCCACTTC ACAGGGACTC CTGATCCGCT CTGTTCAGGG TTCTGACCAA 
GGACTTTATC ACTGCATTGC TACAGAAAAT AGTTTCAAGC AGACCATAGC CAAGATCAAC 
TTCAAAGTTT TAGATTCAGA AATGGTGGCT GTTGTGACGG ACAAATGGTC CCCATGGACC 
TGGGCCAGCT CTGTGAGGGC TTTACCCTTC CACCCGAAGG ACATCATGGG GGCATTCAGC 
CACTCAGAAA TGCAGATGAT TAACCAATAT TGCAAAGACA CTCGGCAGCA ACATCAGCAG 
GGAGATGAAT CACAGAAAAT GAGAGGGGAC TATGGCAAGT TAAAGGCCCT CATCAATAGT 
CGGAAAAGTA GAAACAGGAG GAATCAGTTG CCAGAGTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005250170.1
CDS	658..2739
Translation	MDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINSRKSRNRRNQLPES

Target ORF information:

RefSeq Version	XM_005250113.2
Organism	Homo sapiens(human)
Definition	Homo sapiens semaphorin 3C (SEMA3C), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005250113.2

ORF Insert Sequence:

ATGGATGAAG ATCAGGACCG GATATATGTG GGAAGCAAAG ATCACATTCT TTCCCTGAAT 
ATTAACAATA TAAGTCAAGA AGCTTTGAGT GTTTTCTGGC CAGCATCTAC AATCAAAGTT 
GAAGAATGCA AAATGGCTGG CAAAGATCCC ACACACGGCT GTGGGAACTT TGTCCGTGTA 
ATTCAGACTT TCAATCGCAC ACATTTGTAT GTCTGTGGGA GTGGCGCTTT CAGTCCTGTC 
TGTACTTACT TGAACAGAGG GAGGAGATCA GAGGACCAAG TTTTCATGAT TGACTCCAAG 
TGTGAATCTG GAAAAGGACG CTGCTCTTTC AACCCCAACG TGAACACGGT GTCTGTTATG 
ATCAATGAGG AGCTTTTCTC TGGAATGTAT ATAGATTTCA TGGGGACAGA TGCTGCTATT 
TTTCGAAGTT TAACCAAGAG GAATGCGGTC AGAACTGATC AACATAATTC CAAATGGCTA 
AGTGAACCTA TGTTTGTAGA TGCACATGTC ATCCCAGATG GTACTGATCC AAATGATGCT 
AAGGTGTACT TCTTCTTCAA AGAAAAACTG ACTGACAATA ACAGGAGCAC GAAACAGATT 
CATTCCATGA TTGCTCGAAT ATGTCCTAAT GACACTGGTG GACTGCGTAG CCTTGTCAAC 
AAGTGGACCA CTTTCTTAAA GGCGAGGCTG GTGTGCTCGG TAACAGATGA AGACGGCCCA 
GAAACACACT TTGATGAATT AGAGGATGTG TTTCTGCTGG AAACTGATAA CCCGAGGACA 
ACACTAGTGT ATGGCATTTT TACAACATCA AGCTCAGTTT TCAAAGGATC AGCCGTGTGT 
GTGTATCATT TATCTGATAT ACAGACTGTG TTTAATGGGC CTTTTGCCCA CAAAGAAGGG 
CCCAATCATC AGCTGATTTC CTATCAGGGC AGAATTCCAT ATCCTCGCCC TGGAACTTGT 
CCAGGAGGAG CATTTACACC CAATATGCGA ACCACCAAGG AGTTCCCAGA TGATGTTGTC 
ACTTTTATTC GGAACCATCC TCTCATGTAC AATTCCATCT ACCCAATCCA CAAAAGGCCT 
TTGATTGTTC GTATTGGCAC TGACTACAAG TATACAAAGA TAGCTGTGGA TCGAGTGAAC 
GCTGCTGATG GGAGATACCA TGTCCTGTTT CTCGGAACAG ATCGGGGTAC TGTGCAAAAA 
GTGGTTGTTC TTCCTACTAA CAACTCTGTC AGTGGCGAGC TCATTCTGGA GGAGCTGGAA 
GTCTTTAAGA ATCATGCTCC TATAACAACA ATGAAAATTT CATCTAAAAA GCAACAGTTG 
TATGTGAGTT CCAATGAAGG GGTTTCCCAG GTATCTCTGC ACCGCTGCCA CATCTATGGT 
ACAGCCTGTG CTGACTGCTG CCTGGCGCGG GACCCTTATT GCGCCTGGGA TGGCCATTCC 
TGTTCCAGAT TCTACCCAAC TGGGAAACGG AGGAGCCGAA GACAAGATGT GAGACATGGA 
AACCCACTGA CTCAATGCAG AGGATTTAAT CTAAAAGCAT ACAGAAATGC AGCTGAAATT 
GTCCAGTATG GAGTAAAAAA TAACACCACT TTTCTGGAGT GTGCCCCCAA GTCTCCGCAG 
GCATCTATCA AGTGGCTGTT ACAGAAAGAC AAAGACAGGA GGAAAGAGGT TAAGCTGAAT 
GAACGAATAA TAGCCACTTC ACAGGGACTC CTGATCCGCT CTGTTCAGGG TTCTGACCAA 
GGACTTTATC ACTGCATTGC TACAGAAAAT AGTTTCAAGC AGACCATAGC CAAGATCAAC 
TTCAAAGTTT TAGATTCAGA AATGGTGGCT GTTGTGACGG ACAAATGGTC CCCATGGACC 
TGGGCCAGCT CTGTGAGGGC TTTACCCTTC CACCCGAAGG ACATCATGGG GGCATTCAGC 
CACTCAGAAA TGCAGATGAT TAACCAATAT TGCAAAGACA CTCGGCAGCA ACATCAGCAG 
GGAGATGAAT CACAGAAAAT GAGAGGGGAC TATGGCAAGT TAAAGGCCCT CATCAATAGT 
CGGAAAAGTA GAAACAGGAG GAATCAGTTG CCAGAGTCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEMA3C ( NM_001350120.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001337049.1 Homo sapiens semaphorin 3C (SEMA3C), transcript variant 1, mRNA.

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CloneID	OHu102647
Clone ID Related Accession (Same CDS sequence)	NM_001350120.1 , NM_001350120.2
Accession Version	NM_001350120.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2310bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-04
Organism	Homo sapiens(human)
Product	semaphorin-3C isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC415474.1, AK304294.1, AB000220.1, BC030690.1, CN334969.1, CN334967.1, AA853650.1, BM473251.1 and AI491966.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304294.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTAAGCA AAAAAGGTAT TTTCCCTTGG ATATTAACTT GCATATCTGA AGAAATGGCA 
TTCCGGACAA TTTGCGTGTT GGTTGGAGTA TTTATTTGTT CTATCTGTGT GAAAGGATCT 
TCCCAGCCCC AAGCAAGAGT TTATTTAACA TTTGATGAAC TTCGAGAAAC CAAGACCTCT 
GAATACTTCA GCCTTTCCCA CCATCCTTTA GACTACAGGA TTTTATTAAT GGATGAAGAT 
CAGGACCGGA TATATGTGGG AAGCAAAGAT CACATTCTTT CCCTGAATAT TAACAATATA 
AGTCAAGAAG CTTTGAGTGT TTTCTGGCCA GCATCTACAA TCAAAGTTGA AGAATGCAAA 
ATGGCTGGCA AAGATCCCAC ACACGGCTGT GGGAACTTTG TCCGTGTAAT TCAGACTTTC 
AATCGCACAC ATTTGTATGT CTGTGGGAGT GGCGCTTTCA GTCCTGTCTG TACTTACTTG 
AACAGAGGGA GGAGATCAGA GGACCAAGTT TTCATGATTG ACTCCAAGTG TGAATCTGGA 
AAAGGACGCT GCTCTTTCAA CCCCAACGTG AACACGGTGT CTGTTATGAT CAATGAGGAG 
CTTTTCTCTG GAATGTATAT AGATTTCATG GGGACAGATG CTGCTATTTT TCGAAGTTTA 
ACCAAGAGGA ATGCGGTCAG AACTGATCAA CATAATTCCA AATGGCTAAG TGAACCTATG 
TTTGTAGATG CACATGTCAT CCCAGATGGT ACTGATCCAA ATGATGCTAA GGTGTACTTC 
TTCTTCAAAG AAAAACTGAC TGACAATAAC AGGAGCACGA AACAGATTCA TTCCATGATT 
GCTCGAATAT GTCCTAATGA CACTGGTGGA CTGCGTAGCC TTGTCAACAA GTGGACCACT 
TTCTTAAAGG CGAGGCTGGT GTGCTCGGTA ACAGATGAAG ACGGCCCAGA AACACACTTT 
GATGAATTAG AGGATGTGTT TCTGCTGGAA ACTGATAACC CGAGGACAAC ACTAGTGTAT 
GGCATTTTTA CAACATCAAG CTCAGTTTTC AAAGGATCAG CCGTGTGTGT GTATCATTTA 
TCTGATATAC AGACTGTGTT TAATGGGCCT TTTGCCCACA AAGAAGGGCC CAATCATCAG 
CTGATTTCCT ATCAGGGCAG AATTCCATAT CCTCGCCCTG GAACTTGTCC AGGAGGAGCA 
TTTACACCCA ATATGCGAAC CACCAAGGAG TTCCCAGATG ATGTTGTCAC TTTTATTCGG 
AACCATCCTC TCATGTACAA TTCCATCTAC CCAATCCACA AAAGGCCTTT GATTGTTCGT 
ATTGGCACTG ACTACAAGTA TACAAAGATA GCTGTGGATC GAGTGAACGC TGCTGATGGG 
AGATACCATG TCCTGTTTCT CGGAACAGAT CGGGGTACTG TGCAAAAAGT GGTTGTTCTT 
CCTACTAACA ACTCTGTCAG TGGCGAGCTC ATTCTGGAGG AGCTGGAAGT CTTTAAGAAT 
CATGCTCCTA TAACAACAAT GAAAATTTCA TCTAAAAAGC AACAGTTGTA TGTGAGTTCC 
AATGAAGGGG TTTCCCAGGT ATCTCTGCAC CGCTGCCACA TCTATGGTAC AGCCTGTGCT 
GACTGCTGCC TGGCGCGGGA CCCTTATTGC GCCTGGGATG GCCATTCCTG TTCCAGATTC 
TACCCAACTG GGAAACGGAG GAGCCGAAGA CAAGATGTGA GACATGGAAA CCCACTGACT 
CAATGCAGAG GATTTAATCT AAAAGCATAC AGAAATGCAG CTGAAATTGT CCAGTATGGA 
GTAAAAAATA ACACCACTTT TCTGGAGTGT GCCCCCAAGT CTCCGCAGGC ATCTATCAAG 
TGGCTGTTAC AGAAAGACAA AGACAGGAGG AAAGAGGTTA AGCTGAATGA ACGAATAATA 
GCCACTTCAC AGGGACTCCT GATCCGCTCT GTTCAGGGTT CTGACCAAGG ACTTTATCAC 
TGCATTGCTA CAGAAAATAG TTTCAAGCAG ACCATAGCCA AGATCAACTT CAAAGTTTTA 
GATTCAGAAA TGGTGGCTGT TGTGACGGAC AAATGGTCCC CATGGACCTG GGCCAGCTCT 
GTGAGGGCTT TACCCTTCCA CCCGAAGGAC ATCATGGGGG CATTCAGCCA CTCAGAAATG 
CAGATGATTA ACCAATATTG CAAAGACACT CGGCAGCAAC ATCAGCAGGG AGATGAATCA 
CAGAAAATGA GAGGGGACTA TGGCAAGTTA AAGGCCCTCA TCAATAGTCG GAAAAGTAGA 
AACAGGAGGA ATCAGTTGCC AGAGTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001337049.1
CDS	100..2409
Translation	MLSKKGIFPWILTCISEEMAFRTICVLVGVFICSICVKGSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINSRKSRNRRNQLPES

Target ORF information:

RefSeq Version	NM_001350120.1
Organism	Homo sapiens(human)
Definition	Homo sapiens semaphorin 3C (SEMA3C), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001350120.1

ORF Insert Sequence:

ATGTTAAGCA AAAAAGGTAT TTTCCCTTGG ATATTAACTT GCATATCTGA AGAAATGGCA 
TTCCGGACAA TTTGCGTGTT GGTTGGAGTA TTTATTTGTT CTATCTGTGT GAAAGGATCT 
TCCCAGCCCC AAGCAAGAGT TTATTTAACA TTTGATGAAC TTCGAGAAAC CAAGACCTCT 
GAATACTTCA GCCTTTCCCA CCATCCTTTA GACTACAGGA TTTTATTAAT GGATGAAGAT 
CAGGACCGGA TATATGTGGG AAGCAAAGAT CACATTCTTT CCCTGAATAT TAACAATATA 
AGTCAAGAAG CTTTGAGTGT TTTCTGGCCA GCATCTACAA TCAAAGTTGA AGAATGCAAA 
ATGGCTGGCA AAGATCCCAC ACACGGCTGT GGGAACTTTG TCCGTGTAAT TCAGACTTTC 
AATCGCACAC ATTTGTATGT CTGTGGGAGT GGCGCTTTCA GTCCTGTCTG TACTTACTTG 
AACAGAGGGA GGAGATCAGA GGACCAAGTT TTCATGATTG ACTCCAAGTG TGAATCTGGA 
AAAGGACGCT GCTCTTTCAA CCCCAACGTG AACACGGTGT CTGTTATGAT CAATGAGGAG 
CTTTTCTCTG GAATGTATAT AGATTTCATG GGGACAGATG CTGCTATTTT TCGAAGTTTA 
ACCAAGAGGA ATGCGGTCAG AACTGATCAA CATAATTCCA AATGGCTAAG TGAACCTATG 
TTTGTAGATG CACATGTCAT CCCAGATGGT ACTGATCCAA ATGATGCTAA GGTGTACTTC 
TTCTTCAAAG AAAAACTGAC TGACAATAAC AGGAGCACGA AACAGATTCA TTCCATGATT 
GCTCGAATAT GTCCTAATGA CACTGGTGGA CTGCGTAGCC TTGTCAACAA GTGGACCACT 
TTCTTAAAGG CGAGGCTGGT GTGCTCGGTA ACAGATGAAG ACGGCCCAGA AACACACTTT 
GATGAATTAG AGGATGTGTT TCTGCTGGAA ACTGATAACC CGAGGACAAC ACTAGTGTAT 
GGCATTTTTA CAACATCAAG CTCAGTTTTC AAAGGATCAG CCGTGTGTGT GTATCATTTA 
TCTGATATAC AGACTGTGTT TAATGGGCCT TTTGCCCACA AAGAAGGGCC CAATCATCAG 
CTGATTTCCT ATCAGGGCAG AATTCCATAT CCTCGCCCTG GAACTTGTCC AGGAGGAGCA 
TTTACACCCA ATATGCGAAC CACCAAGGAG TTCCCAGATG ATGTTGTCAC TTTTATTCGG 
AACCATCCTC TCATGTACAA TTCCATCTAC CCAATCCACA AAAGGCCTTT GATTGTTCGT 
ATTGGCACTG ACTACAAGTA TACAAAGATA GCTGTGGATC GAGTGAACGC TGCTGATGGG 
AGATACCATG TCCTGTTTCT CGGAACAGAT CGGGGTACTG TGCAAAAAGT GGTTGTTCTT 
CCTACTAACA ACTCTGTCAG TGGCGAGCTC ATTCTGGAGG AGCTGGAAGT CTTTAAGAAT 
CATGCTCCTA TAACAACAAT GAAAATTTCA TCTAAAAAGC AACAGTTGTA TGTGAGTTCC 
AATGAAGGGG TTTCCCAGGT ATCTCTGCAC CGCTGCCACA TCTATGGTAC AGCCTGTGCT 
GACTGCTGCC TGGCGCGGGA CCCTTATTGC GCCTGGGATG GCCATTCCTG TTCCAGATTC 
TACCCAACTG GGAAACGGAG GAGCCGAAGA CAAGATGTGA GACATGGAAA CCCACTGACT 
CAATGCAGAG GATTTAATCT AAAAGCATAC AGAAATGCAG CTGAAATTGT CCAGTATGGA 
GTAAAAAATA ACACCACTTT TCTGGAGTGT GCCCCCAAGT CTCCGCAGGC ATCTATCAAG 
TGGCTGTTAC AGAAAGACAA AGACAGGAGG AAAGAGGTTA AGCTGAATGA ACGAATAATA 
GCCACTTCAC AGGGACTCCT GATCCGCTCT GTTCAGGGTT CTGACCAAGG ACTTTATCAC 
TGCATTGCTA CAGAAAATAG TTTCAAGCAG ACCATAGCCA AGATCAACTT CAAAGTTTTA 
GATTCAGAAA TGGTGGCTGT TGTGACGGAC AAATGGTCCC CATGGACCTG GGCCAGCTCT 
GTGAGGGCTT TACCCTTCCA CCCGAAGGAC ATCATGGGGG CATTCAGCCA CTCAGAAATG 
CAGATGATTA ACCAATATTG CAAAGACACT CGGCAGCAAC ATCAGCAGGG AGATGAATCA 
CAGAAAATGA GAGGGGACTA TGGCAAGTTA AAGGCCCTCA TCAATAGTCG GAAAAGTAGA 
AACAGGAGGA ATCAGTTGCC AGAGTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SEMA3C ( NM_001350120.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001337049.1 Homo sapiens semaphorin 3C (SEMA3C), transcript variant 1, mRNA.

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CloneID	OHu102647
Clone ID Related Accession (Same CDS sequence)	NM_001350120.1 , NM_001350120.2
Accession Version	NM_001350120.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2310bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-09
Organism	Homo sapiens(human)
Product	semaphorin-3C isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC004972.2, DC415474.1, AK304294.1, AB000220.1, BC030690.1, CN334969.1, CN334967.1, AA853650.1 and BM473251.1. On May 31, 2019 this sequence version replaced NM_001350120.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304294.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTAAGCA AAAAAGGTAT TTTCCCTTGG ATATTAACTT GCATATCTGA AGAAATGGCA 
TTCCGGACAA TTTGCGTGTT GGTTGGAGTA TTTATTTGTT CTATCTGTGT GAAAGGATCT 
TCCCAGCCCC AAGCAAGAGT TTATTTAACA TTTGATGAAC TTCGAGAAAC CAAGACCTCT 
GAATACTTCA GCCTTTCCCA CCATCCTTTA GACTACAGGA TTTTATTAAT GGATGAAGAT 
CAGGACCGGA TATATGTGGG AAGCAAAGAT CACATTCTTT CCCTGAATAT TAACAATATA 
AGTCAAGAAG CTTTGAGTGT TTTCTGGCCA GCATCTACAA TCAAAGTTGA AGAATGCAAA 
ATGGCTGGCA AAGATCCCAC ACACGGCTGT GGGAACTTTG TCCGTGTAAT TCAGACTTTC 
AATCGCACAC ATTTGTATGT CTGTGGGAGT GGCGCTTTCA GTCCTGTCTG TACTTACTTG 
AACAGAGGGA GGAGATCAGA GGACCAAGTT TTCATGATTG ACTCCAAGTG TGAATCTGGA 
AAAGGACGCT GCTCTTTCAA CCCCAACGTG AACACGGTGT CTGTTATGAT CAATGAGGAG 
CTTTTCTCTG GAATGTATAT AGATTTCATG GGGACAGATG CTGCTATTTT TCGAAGTTTA 
ACCAAGAGGA ATGCGGTCAG AACTGATCAA CATAATTCCA AATGGCTAAG TGAACCTATG 
TTTGTAGATG CACATGTCAT CCCAGATGGT ACTGATCCAA ATGATGCTAA GGTGTACTTC 
TTCTTCAAAG AAAAACTGAC TGACAATAAC AGGAGCACGA AACAGATTCA TTCCATGATT 
GCTCGAATAT GTCCTAATGA CACTGGTGGA CTGCGTAGCC TTGTCAACAA GTGGACCACT 
TTCTTAAAGG CGAGGCTGGT GTGCTCGGTA ACAGATGAAG ACGGCCCAGA AACACACTTT 
GATGAATTAG AGGATGTGTT TCTGCTGGAA ACTGATAACC CGAGGACAAC ACTAGTGTAT 
GGCATTTTTA CAACATCAAG CTCAGTTTTC AAAGGATCAG CCGTGTGTGT GTATCATTTA 
TCTGATATAC AGACTGTGTT TAATGGGCCT TTTGCCCACA AAGAAGGGCC CAATCATCAG 
CTGATTTCCT ATCAGGGCAG AATTCCATAT CCTCGCCCTG GAACTTGTCC AGGAGGAGCA 
TTTACACCCA ATATGCGAAC CACCAAGGAG TTCCCAGATG ATGTTGTCAC TTTTATTCGG 
AACCATCCTC TCATGTACAA TTCCATCTAC CCAATCCACA AAAGGCCTTT GATTGTTCGT 
ATTGGCACTG ACTACAAGTA TACAAAGATA GCTGTGGATC GAGTGAACGC TGCTGATGGG 
AGATACCATG TCCTGTTTCT CGGAACAGAT CGGGGTACTG TGCAAAAAGT GGTTGTTCTT 
CCTACTAACA ACTCTGTCAG TGGCGAGCTC ATTCTGGAGG AGCTGGAAGT CTTTAAGAAT 
CATGCTCCTA TAACAACAAT GAAAATTTCA TCTAAAAAGC AACAGTTGTA TGTGAGTTCC 
AATGAAGGGG TTTCCCAGGT ATCTCTGCAC CGCTGCCACA TCTATGGTAC AGCCTGTGCT 
GACTGCTGCC TGGCGCGGGA CCCTTATTGC GCCTGGGATG GCCATTCCTG TTCCAGATTC 
TACCCAACTG GGAAACGGAG GAGCCGAAGA CAAGATGTGA GACATGGAAA CCCACTGACT 
CAATGCAGAG GATTTAATCT AAAAGCATAC AGAAATGCAG CTGAAATTGT CCAGTATGGA 
GTAAAAAATA ACACCACTTT TCTGGAGTGT GCCCCCAAGT CTCCGCAGGC ATCTATCAAG 
TGGCTGTTAC AGAAAGACAA AGACAGGAGG AAAGAGGTTA AGCTGAATGA ACGAATAATA 
GCCACTTCAC AGGGACTCCT GATCCGCTCT GTTCAGGGTT CTGACCAAGG ACTTTATCAC 
TGCATTGCTA CAGAAAATAG TTTCAAGCAG ACCATAGCCA AGATCAACTT CAAAGTTTTA 
GATTCAGAAA TGGTGGCTGT TGTGACGGAC AAATGGTCCC CATGGACCTG GGCCAGCTCT 
GTGAGGGCTT TACCCTTCCA CCCGAAGGAC ATCATGGGGG CATTCAGCCA CTCAGAAATG 
CAGATGATTA ACCAATATTG CAAAGACACT CGGCAGCAAC ATCAGCAGGG AGATGAATCA 
CAGAAAATGA GAGGGGACTA TGGCAAGTTA AAGGCCCTCA TCAATAGTCG GAAAAGTAGA 
AACAGGAGGA ATCAGTTGCC AGAGTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001337049.1
CDS	110..2419
Translation	MLSKKGIFPWILTCISEEMAFRTICVLVGVFICSICVKGSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINSRKSRNRRNQLPES

Target ORF information:

RefSeq Version	NM_001350120.2
Organism	Homo sapiens(human)
Definition	Homo sapiens semaphorin 3C (SEMA3C), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001350120.2

ORF Insert Sequence:

ATGTTAAGCA AAAAAGGTAT TTTCCCTTGG ATATTAACTT GCATATCTGA AGAAATGGCA 
TTCCGGACAA TTTGCGTGTT GGTTGGAGTA TTTATTTGTT CTATCTGTGT GAAAGGATCT 
TCCCAGCCCC AAGCAAGAGT TTATTTAACA TTTGATGAAC TTCGAGAAAC CAAGACCTCT 
GAATACTTCA GCCTTTCCCA CCATCCTTTA GACTACAGGA TTTTATTAAT GGATGAAGAT 
CAGGACCGGA TATATGTGGG AAGCAAAGAT CACATTCTTT CCCTGAATAT TAACAATATA 
AGTCAAGAAG CTTTGAGTGT TTTCTGGCCA GCATCTACAA TCAAAGTTGA AGAATGCAAA 
ATGGCTGGCA AAGATCCCAC ACACGGCTGT GGGAACTTTG TCCGTGTAAT TCAGACTTTC 
AATCGCACAC ATTTGTATGT CTGTGGGAGT GGCGCTTTCA GTCCTGTCTG TACTTACTTG 
AACAGAGGGA GGAGATCAGA GGACCAAGTT TTCATGATTG ACTCCAAGTG TGAATCTGGA 
AAAGGACGCT GCTCTTTCAA CCCCAACGTG AACACGGTGT CTGTTATGAT CAATGAGGAG 
CTTTTCTCTG GAATGTATAT AGATTTCATG GGGACAGATG CTGCTATTTT TCGAAGTTTA 
ACCAAGAGGA ATGCGGTCAG AACTGATCAA CATAATTCCA AATGGCTAAG TGAACCTATG 
TTTGTAGATG CACATGTCAT CCCAGATGGT ACTGATCCAA ATGATGCTAA GGTGTACTTC 
TTCTTCAAAG AAAAACTGAC TGACAATAAC AGGAGCACGA AACAGATTCA TTCCATGATT 
GCTCGAATAT GTCCTAATGA CACTGGTGGA CTGCGTAGCC TTGTCAACAA GTGGACCACT 
TTCTTAAAGG CGAGGCTGGT GTGCTCGGTA ACAGATGAAG ACGGCCCAGA AACACACTTT 
GATGAATTAG AGGATGTGTT TCTGCTGGAA ACTGATAACC CGAGGACAAC ACTAGTGTAT 
GGCATTTTTA CAACATCAAG CTCAGTTTTC AAAGGATCAG CCGTGTGTGT GTATCATTTA 
TCTGATATAC AGACTGTGTT TAATGGGCCT TTTGCCCACA AAGAAGGGCC CAATCATCAG 
CTGATTTCCT ATCAGGGCAG AATTCCATAT CCTCGCCCTG GAACTTGTCC AGGAGGAGCA 
TTTACACCCA ATATGCGAAC CACCAAGGAG TTCCCAGATG ATGTTGTCAC TTTTATTCGG 
AACCATCCTC TCATGTACAA TTCCATCTAC CCAATCCACA AAAGGCCTTT GATTGTTCGT 
ATTGGCACTG ACTACAAGTA TACAAAGATA GCTGTGGATC GAGTGAACGC TGCTGATGGG 
AGATACCATG TCCTGTTTCT CGGAACAGAT CGGGGTACTG TGCAAAAAGT GGTTGTTCTT 
CCTACTAACA ACTCTGTCAG TGGCGAGCTC ATTCTGGAGG AGCTGGAAGT CTTTAAGAAT 
CATGCTCCTA TAACAACAAT GAAAATTTCA TCTAAAAAGC AACAGTTGTA TGTGAGTTCC 
AATGAAGGGG TTTCCCAGGT ATCTCTGCAC CGCTGCCACA TCTATGGTAC AGCCTGTGCT 
GACTGCTGCC TGGCGCGGGA CCCTTATTGC GCCTGGGATG GCCATTCCTG TTCCAGATTC 
TACCCAACTG GGAAACGGAG GAGCCGAAGA CAAGATGTGA GACATGGAAA CCCACTGACT 
CAATGCAGAG GATTTAATCT AAAAGCATAC AGAAATGCAG CTGAAATTGT CCAGTATGGA 
GTAAAAAATA ACACCACTTT TCTGGAGTGT GCCCCCAAGT CTCCGCAGGC ATCTATCAAG 
TGGCTGTTAC AGAAAGACAA AGACAGGAGG AAAGAGGTTA AGCTGAATGA ACGAATAATA 
GCCACTTCAC AGGGACTCCT GATCCGCTCT GTTCAGGGTT CTGACCAAGG ACTTTATCAC 
TGCATTGCTA CAGAAAATAG TTTCAAGCAG ACCATAGCCA AGATCAACTT CAAAGTTTTA 
GATTCAGAAA TGGTGGCTGT TGTGACGGAC AAATGGTCCC CATGGACCTG GGCCAGCTCT 
GTGAGGGCTT TACCCTTCCA CCCGAAGGAC ATCATGGGGG CATTCAGCCA CTCAGAAATG 
CAGATGATTA ACCAATATTG CAAAGACACT CGGCAGCAAC ATCAGCAGGG AGATGAATCA 
CAGAAAATGA GAGGGGACTA TGGCAAGTTA AAGGCCCTCA TCAATAGTCG GAAAAGTAGA 
AACAGGAGGA ATCAGTTGCC AGAGTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Class 3 semaphorins are transcriptionally regulated by 1,25(OH)
The Journal of steroid biochemistry and molecular biology173185-193(2017 10)
Ryyn?nen J,Kriebitzsch C,Meyer MB,Janssens I,Pike JW,Verlinden L,Verstuyf A

Semaphorin 3?C drives epithelial-to-mesenchymal transition, invasiveness, and stem-like characteristics in prostate cells.
Scientific reports7(1)11501(2017 Sep)
Tam KJ,Hui DHF,Lee WW,Dong M,Tombe T,Jiao IZF,Khosravi S,Takeuchi A,Peacock JW,Ivanova L,Moskalev I,Gleave ME,Buttyan R,Cox ME,Ong CJ

Increased semaphorin 3c expression promotes tumor growth and metastasis in pancreatic ductal adenocarcinoma by activating the ERK1/2 signaling pathway.
Cancer letters39712-22(2017 Jul)
Xu X,Zhao Z,Guo S,Li J,Liu S,You Y,Ni B,Wang H,Bie P

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SEMA3C cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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