PSME3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PSME3
Entrez Gene ID	10197
Full Name	proteasome activator subunit 3
Synonyms	HEL-S-283,Ki,PA28-gamma,PA28G,PA28gamma,REG-GAMMA
General protein information	Preferred Names proteasome activator subunit 3 Names proteasome activator complex subunit 3 11S regulator complex gamma subunit 11S regulator complex subunit gamma Ki antigen Ki nuclear autoantigen PA28 gamma variant 5 REG gamma-3 activator of multicatalytic protease subunit 3 epididymis secretory protein Li 283 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) proteasome activator 28 subunit gamma proteasome activator 28-gamma
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.31
Summary	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012].
Disorder MIM:	605129

mRNA and Protein(s)

mRNA	Protein	Name
NM_176863.3	NP_789839.1	proteasome activator complex subunit 3 isoform 2
NM_005789.3	NP_005780.2	proteasome activator complex subunit 3 isoform 1
NM_005789.4	NP_005780.2	proteasome activator complex subunit 3 isoform 1
NM_001330229.1	NP_001317158.1	proteasome activator complex subunit 3 isoform 4
NM_001267045.1	NP_001253974.1	proteasome activator complex subunit 3 isoform 3
NM_001330229.2	NP_001317158.1	proteasome activator complex subunit 3 isoform 4
NM_001267045.2	NP_001253974.1	proteasome activator complex subunit 3 isoform 3
NM_176863.2	NP_789839.1	proteasome activator complex subunit 3 isoform 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	PSME3	XP_002696046.1
Mus musculus (house mouse)	Psme3	NP_035322.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000308	XP_310815.3
Caenorhabditis elegans (roundworm)	Y66D12A.9	NP_499493.1
Homo sapiens (human)	PSME3	NP_789839.1
Pan troglodytes (chimpanzee)	PSME3	NP_001238824.1
Rattus norvegicus (Norway rat)	Psme3	NP_001011894.1
Gallus gallus (chicken)	PSME3	NP_001012568.1
Danio rerio (zebrafish)	psme3	NP_571451.2
Drosophila melanogaster (fruit fly)	REG	NP_572866.1
Xenopus tropicalis (tropical clawed frog)	psme3	NP_001096200.1
	LOC711900	XP_002800535.1
Canis lupus familiaris (dog)	PSME3	XP_003435263.1

Gene Ontology
Bibliography

Related articles in PubMed

Knockdown of REG? inhibits the proliferation and migration and promotes the apoptosis of multiple myeloma cells by downregulating NF-?B signal pathway.
Liu S, Zheng LL, Zhu YM, Shen HJ, Zhong Q, Huang J, Li C, Liu Z, Yao MD, Ou RM, Zhang Q
Hematology (Amsterdam, Netherlands)1-7(2017 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

that Proteasome activator subunit 3 induces epithelial-mesenchymal transition with inducing the expression of CSC markers and influencing the tumor immune microenvironment in breast cancer
Title: PSME3 induces epithelial-mesenchymal transition with inducing the expression of CSC markers and immunosuppression in breast cancer.

PSME3 plays an oncogenic role in pancreatic cancer by inhibiting c-Myc degradation to promote glycolysis.
Title: Proteasome activator subunit 3 promotes pancreatic cancer growth via c-Myc-glycolysis signaling axis.

Study demonstrated that the gene therapy with proteasome activator, PA28gamma can improve ubiquitin-proteasome system function as well as behavioral abnormalities in Huntington's disease model mice
Title: Gene therapy by proteasome activator, PA28?, improves motor coordination and proteasome function in Huntington's disease YAC128 mice.

Surrogate Prognostic Biomarkers in OSCC: The Paradigm of PA28gamma Overexpression.
Title: Surrogate Prognostic Biomarkers in OSCC: The Paradigm of PA28? Overexpression.

PA28gamma in OSCC tumor tissues were significantly high expression than those in normal tissues.
Title: Associations between proteasomal activator PA28? and outcome of oral squamous cell carcinoma: Evidence from cohort studies and functional analyses.

The following PSME3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PSME3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08415	NM_005789.4 Latest version!	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu63756	NM_001330229.2 Latest version!	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu07985	NM_176863.3 Latest version!	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu08462	NM_001267045.2 Latest version!	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu08415	NM_005789.3	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu63756	NM_001330229.1	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
OHu08462	NM_001267045.1	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu07985	NM_176863.2	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PSME3 ( NM_005789.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005780.2 Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08415
Clone ID Related Accession (Same CDS sequence)	NM_005789.3 , NM_005789.4
Accession Version	NM_005789.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 765bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	proteasome activator complex subunit 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI464061.1, BC001423.2, AC016889.28 and AI304773.1. On May 26, 2012 this sequence version replaced NM_005789.2. Transcript Variant: This variant (1) encodes the predominant isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.72502.1, SRR1803615.151605.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCGT TGCTGAAGGT GGATCAGGAA GTGAAGCTCA AGGTTGATTC TTTCAGGGAG 
CGGATCACAA GTGAGGCAGA AGACTTGGTG GCAAATTTTT TCCCAAAGAA GTTATTAGAA 
CTTGATAGTT TTCTGAAGGA ACCAATCTTA AACATCCATG ACCTAACTCA GATCCACTCT 
GACATGAATC TCCCAGTCCC TGACCCCATT CTTCTCACCA ATAGCCATGA TGGACTGGAT 
GGTCCCACTT ATAAGAAGCG AAGGTTGGAT GAGTGTGAAG AAGCCTTCCA AGGAACCAAG 
GTGTTTGTGA TGCCCAATGG GATGCTGAAA AGCAACCAGC AGCTGGTGGA CATTATTGAG 
AAAGTGAAAC CTGAGATCCG GCTGTTGATT GAGAAATGTA ACACGGTCAA AATGTGGGTA 
CAGCTCCTGA TTCCCAGGAT AGAAGATGGA AACAACTTTG GGGTGTCCAT TCAGGAGGAA 
ACAGTTGCAG AGCTAAGAAC TGTTGAGAGT GAAGCTGCAT CTTATCTGGA CCAGATTTCT 
AGATATTATA TTACAAGAGC CAAATTGGTT TCTAAAATAG CTAAATATCC CCATGTGGAG 
GACTATCGCC GCACCGTGAC AGAGATTGAT GAGAAAGAAT ATATCAGCCT TCGGCTCATC 
ATATCAGAGC TGAGGAATCA ATATGTCACT CTACATGACA TGATCCTGAA AAATATCGAG 
AAGATCAAAC GGCCCCGGAG CAGCAATGCA GAGACTCTGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005780.2
CDS	491..1255
Translation	MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY

Target ORF information:

RefSeq Version	NM_005789.3
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005789.3

ORF Insert Sequence:

ATGGCCTCGT TGCTGAAGGT GGATCAGGAA GTGAAGCTCA AGGTTGATTC TTTCAGGGAG 
CGGATCACAA GTGAGGCAGA AGACTTGGTG GCAAATTTTT TCCCAAAGAA GTTATTAGAA 
CTTGATAGTT TTCTGAAGGA ACCAATCTTA AACATCCATG ACCTAACTCA GATCCACTCT 
GACATGAATC TCCCAGTCCC TGACCCCATT CTTCTCACCA ATAGCCATGA TGGACTGGAT 
GGTCCCACTT ATAAGAAGCG AAGGTTGGAT GAGTGTGAAG AAGCCTTCCA AGGAACCAAG 
GTGTTTGTGA TGCCCAATGG GATGCTGAAA AGCAACCAGC AGCTGGTGGA CATTATTGAG 
AAAGTGAAAC CTGAGATCCG GCTGTTGATT GAGAAATGTA ACACGGTCAA AATGTGGGTA 
CAGCTCCTGA TTCCCAGGAT AGAAGATGGA AACAACTTTG GGGTGTCCAT TCAGGAGGAA 
ACAGTTGCAG AGCTAAGAAC TGTTGAGAGT GAAGCTGCAT CTTATCTGGA CCAGATTTCT 
AGATATTATA TTACAAGAGC CAAATTGGTT TCTAAAATAG CTAAATATCC CCATGTGGAG 
GACTATCGCC GCACCGTGAC AGAGATTGAT GAGAAAGAAT ATATCAGCCT TCGGCTCATC 
ATATCAGAGC TGAGGAATCA ATATGTCACT CTACATGACA TGATCCTGAA AAATATCGAG 
AAGATCAAAC GGCCCCGGAG CAGCAATGCA GAGACTCTGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSME3 ( NM_005789.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005780.2 Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08415
Clone ID Related Accession (Same CDS sequence)	NM_005789.3 , NM_005789.4
Accession Version	NM_005789.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 765bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	proteasome activator complex subunit 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI464061.1, BC001423.2, AC016889.28 and AI304773.1. On May 17, 2019 this sequence version replaced NM_005789.3. Transcript Variant: This variant (1) encodes the predominant isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.72502.1, SRR1803617.89827.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000590720.6/ ENSP00000466794.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCGT TGCTGAAGGT GGATCAGGAA GTGAAGCTCA AGGTTGATTC TTTCAGGGAG 
CGGATCACAA GTGAGGCAGA AGACTTGGTG GCAAATTTTT TCCCAAAGAA GTTATTAGAA 
CTTGATAGTT TTCTGAAGGA ACCAATCTTA AACATCCATG ACCTAACTCA GATCCACTCT 
GACATGAATC TCCCAGTCCC TGACCCCATT CTTCTCACCA ATAGCCATGA TGGACTGGAT 
GGTCCCACTT ATAAGAAGCG AAGGTTGGAT GAGTGTGAAG AAGCCTTCCA AGGAACCAAG 
GTGTTTGTGA TGCCCAATGG GATGCTGAAA AGCAACCAGC AGCTGGTGGA CATTATTGAG 
AAAGTGAAAC CTGAGATCCG GCTGTTGATT GAGAAATGTA ACACGGTCAA AATGTGGGTA 
CAGCTCCTGA TTCCCAGGAT AGAAGATGGA AACAACTTTG GGGTGTCCAT TCAGGAGGAA 
ACAGTTGCAG AGCTAAGAAC TGTTGAGAGT GAAGCTGCAT CTTATCTGGA CCAGATTTCT 
AGATATTATA TTACAAGAGC CAAATTGGTT TCTAAAATAG CTAAATATCC CCATGTGGAG 
GACTATCGCC GCACCGTGAC AGAGATTGAT GAGAAAGAAT ATATCAGCCT TCGGCTCATC 
ATATCAGAGC TGAGGAATCA ATATGTCACT CTACATGACA TGATCCTGAA AAATATCGAG 
AAGATCAAAC GGCCCCGGAG CAGCAATGCA GAGACTCTGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005780.2
CDS	236..1000
Translation	MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY

Target ORF information:

RefSeq Version	NM_005789.4
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005789.4

ORF Insert Sequence:

ATGGCCTCGT TGCTGAAGGT GGATCAGGAA GTGAAGCTCA AGGTTGATTC TTTCAGGGAG 
CGGATCACAA GTGAGGCAGA AGACTTGGTG GCAAATTTTT TCCCAAAGAA GTTATTAGAA 
CTTGATAGTT TTCTGAAGGA ACCAATCTTA AACATCCATG ACCTAACTCA GATCCACTCT 
GACATGAATC TCCCAGTCCC TGACCCCATT CTTCTCACCA ATAGCCATGA TGGACTGGAT 
GGTCCCACTT ATAAGAAGCG AAGGTTGGAT GAGTGTGAAG AAGCCTTCCA AGGAACCAAG 
GTGTTTGTGA TGCCCAATGG GATGCTGAAA AGCAACCAGC AGCTGGTGGA CATTATTGAG 
AAAGTGAAAC CTGAGATCCG GCTGTTGATT GAGAAATGTA ACACGGTCAA AATGTGGGTA 
CAGCTCCTGA TTCCCAGGAT AGAAGATGGA AACAACTTTG GGGTGTCCAT TCAGGAGGAA 
ACAGTTGCAG AGCTAAGAAC TGTTGAGAGT GAAGCTGCAT CTTATCTGGA CCAGATTTCT 
AGATATTATA TTACAAGAGC CAAATTGGTT TCTAAAATAG CTAAATATCC CCATGTGGAG 
GACTATCGCC GCACCGTGAC AGAGATTGAT GAGAAAGAAT ATATCAGCCT TCGGCTCATC 
ATATCAGAGC TGAGGAATCA ATATGTCACT CTACATGACA TGATCCTGAA AAATATCGAG 
AAGATCAAAC GGCCCCGGAG CAGCAATGCA GAGACTCTGT ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSME3 ( NM_001330229.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317158.1 Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu63756
Clone ID Related Accession (Same CDS sequence)	NM_001330229.1 , NM_001330229.2
Accession Version	NM_001330229.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-10-20
Organism	Homo sapiens(human)
Product	proteasome activator complex subunit 3 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC016889.28 and CX866774.1. On Aug 20, 2016 this sequence version replaced XM_011524177.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.199290.1, SRR1803617.53779.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAATCTCC CAGTCCCTGA CCCCATTCTT CTCACCAATA GCCATGATGG ACTGGATGGT 
CCCACTTATA AGAAGCGAAG GTTGGATGAG TGTGAAGAAG CCTTCCAAGG AACCAAGGTG 
TTTGTGATGC CCAATGGGAT GCTGAAAAGC AACCAGCAGC TGGTGGACAT TATTGAGAAA 
GTGAAACCTG AGATCCGGCT GTTGATTGAG AAATGTAACA CGGTCAAAAT GTGGGTACAG 
CTCCTGATTC CCAGGATAGA AGATGGAAAC AACTTTGGGG TGTCCATTCA GGAGGAAACA 
GTTGCAGAGC TAAGAACTGT TGAGAGTGAA GCTGCATCTT ATCTGGACCA GATTTCTAGA 
TATTATATTA CAAGAGCCAA ATTGGTTTCT AAAATAGCTA AATATCCCCA TGTGGAGGAC 
TATCGCCGCA CCGTGACAGA GATTGATGAG AAAGAATATA TCAGCCTTCG GCTCATCATA 
TCAGAGCTGA GGAATCAATA TGTCACTCTA CATGACATGA TCCTGAAAAA TATCGAGAAG 
ATCAAACGGC CCCGGAGCAG CAATGCAGAG ACTCTGTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317158.1
CDS	685..1266
Translation	MNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY

Target ORF information:

RefSeq Version	NM_001330229.1
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330229.1

ORF Insert Sequence:

ATGAATCTCC CAGTCCCTGA CCCCATTCTT CTCACCAATA GCCATGATGG ACTGGATGGT 
CCCACTTATA AGAAGCGAAG GTTGGATGAG TGTGAAGAAG CCTTCCAAGG AACCAAGGTG 
TTTGTGATGC CCAATGGGAT GCTGAAAAGC AACCAGCAGC TGGTGGACAT TATTGAGAAA 
GTGAAACCTG AGATCCGGCT GTTGATTGAG AAATGTAACA CGGTCAAAAT GTGGGTACAG 
CTCCTGATTC CCAGGATAGA AGATGGAAAC AACTTTGGGG TGTCCATTCA GGAGGAAACA 
GTTGCAGAGC TAAGAACTGT TGAGAGTGAA GCTGCATCTT ATCTGGACCA GATTTCTAGA 
TATTATATTA CAAGAGCCAA ATTGGTTTCT AAAATAGCTA AATATCCCCA TGTGGAGGAC 
TATCGCCGCA CCGTGACAGA GATTGATGAG AAAGAATATA TCAGCCTTCG GCTCATCATA 
TCAGAGCTGA GGAATCAATA TGTCACTCTA CATGACATGA TCCTGAAAAA TATCGAGAAG 
ATCAAACGGC CCCGGAGCAG CAATGCAGAG ACTCTGTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSME3 ( NM_001330229.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317158.1 Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu63756
Clone ID Related Accession (Same CDS sequence)	NM_001330229.1 , NM_001330229.2
Accession Version	NM_001330229.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-22
Organism	Homo sapiens(human)
Product	proteasome activator complex subunit 3 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC016889.28 and CX866774.1. On May 31, 2019 this sequence version replaced NM_001330229.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.280667.1, SRR1803617.53779.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAATCTCC CAGTCCCTGA CCCCATTCTT CTCACCAATA GCCATGATGG ACTGGATGGT 
CCCACTTATA AGAAGCGAAG GTTGGATGAG TGTGAAGAAG CCTTCCAAGG AACCAAGGTG 
TTTGTGATGC CCAATGGGAT GCTGAAAAGC AACCAGCAGC TGGTGGACAT TATTGAGAAA 
GTGAAACCTG AGATCCGGCT GTTGATTGAG AAATGTAACA CGGTCAAAAT GTGGGTACAG 
CTCCTGATTC CCAGGATAGA AGATGGAAAC AACTTTGGGG TGTCCATTCA GGAGGAAACA 
GTTGCAGAGC TAAGAACTGT TGAGAGTGAA GCTGCATCTT ATCTGGACCA GATTTCTAGA 
TATTATATTA CAAGAGCCAA ATTGGTTTCT AAAATAGCTA AATATCCCCA TGTGGAGGAC 
TATCGCCGCA CCGTGACAGA GATTGATGAG AAAGAATATA TCAGCCTTCG GCTCATCATA 
TCAGAGCTGA GGAATCAATA TGTCACTCTA CATGACATGA TCCTGAAAAA TATCGAGAAG 
ATCAAACGGC CCCGGAGCAG CAATGCAGAG ACTCTGTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317158.1
CDS	685..1266
Translation	MNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY

Target ORF information:

RefSeq Version	NM_001330229.2
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330229.2

ORF Insert Sequence:

ATGAATCTCC CAGTCCCTGA CCCCATTCTT CTCACCAATA GCCATGATGG ACTGGATGGT 
CCCACTTATA AGAAGCGAAG GTTGGATGAG TGTGAAGAAG CCTTCCAAGG AACCAAGGTG 
TTTGTGATGC CCAATGGGAT GCTGAAAAGC AACCAGCAGC TGGTGGACAT TATTGAGAAA 
GTGAAACCTG AGATCCGGCT GTTGATTGAG AAATGTAACA CGGTCAAAAT GTGGGTACAG 
CTCCTGATTC CCAGGATAGA AGATGGAAAC AACTTTGGGG TGTCCATTCA GGAGGAAACA 
GTTGCAGAGC TAAGAACTGT TGAGAGTGAA GCTGCATCTT ATCTGGACCA GATTTCTAGA 
TATTATATTA CAAGAGCCAA ATTGGTTTCT AAAATAGCTA AATATCCCCA TGTGGAGGAC 
TATCGCCGCA CCGTGACAGA GATTGATGAG AAAGAATATA TCAGCCTTCG GCTCATCATA 
TCAGAGCTGA GGAATCAATA TGTCACTCTA CATGACATGA TCCTGAAAAA TATCGAGAAG 
ATCAAACGGC CCCGGAGCAG CAATGCAGAG ACTCTGTACT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSME3 ( NM_176863.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_789839.1 Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07985
Clone ID Related Accession (Same CDS sequence)	NM_176863.3 , NM_176863.2
Accession Version	NM_176863.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 804bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	proteasome activator complex subunit 3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC016889.28, U11292.1 and AI304773.1. On May 31, 2019 this sequence version replaced NM_176863.2. Transcript Variant: This variant (2), uses ans alternate in-frame splice site, compared to variant 1. The resulting isoform (2) is longer than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U11292.1, SRR1803617.227537.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCGT TGCTGAAGGT GGATCAGGAA GTGAAGCTCA AGGTTGATTC TTTCAGGGAG 
CGGATCACAA GTGAGGCAGA AGACTTGGTG GCAAATTTTT TCCCAAAGAA GTTATTAGAA 
CTTGATAGTT TTCTGAAGGA ACCAATCTTA AACATCCATG ACCTAACTCA GATCCACTCT 
GACATGAATC TCCCAGTCCC TGACCCCATT CTTCTCACCA ATAGCCATGA TGGACTGGAT 
GGTCCCACTT ATAAGAAGCG AAGGTTGGAT GAGTGTGAAG AAGCCTTCCA AGGAACCAAG 
GTGTTTGTGA TGCCCAATGG GATGCTGAAA AGCAACCAGC AGCTGGTGGA CATTATTGAG 
AAAGTGAAAC CTGAGATCCG GCTGTTGATT GAGAAATGTA ACACGCCTTC AGGCAAAGGT 
CCTCATATAT GTTTTGACCT CCAGGTCAAA ATGTGGGTAC AGCTCCTGAT TCCCAGGATA 
GAAGATGGAA ACAACTTTGG GGTGTCCATT CAGGAGGAAA CAGTTGCAGA GCTAAGAACT 
GTTGAGAGTG AAGCTGCATC TTATCTGGAC CAGATTTCTA GATATTATAT TACAAGAGCC 
AAATTGGTTT CTAAAATAGC TAAATATCCC CATGTGGAGG ACTATCGCCG CACCGTGACA 
GAGATTGATG AGAAAGAATA TATCAGCCTT CGGCTCATCA TATCAGAGCT GAGGAATCAA 
TATGTCACTC TACATGACAT GATCCTGAAA AATATCGAGA AGATCAAACG GCCCCGGAGC 
AGCAATGCAG AGACTCTGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_789839.1
CDS	236..1039
Translation	MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTPSGKGPHICFDLQVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY

Target ORF information:

RefSeq Version	NM_176863.3
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176863.3

ORF Insert Sequence:

ATGGCCTCGT TGCTGAAGGT GGATCAGGAA GTGAAGCTCA AGGTTGATTC TTTCAGGGAG 
CGGATCACAA GTGAGGCAGA AGACTTGGTG GCAAATTTTT TCCCAAAGAA GTTATTAGAA 
CTTGATAGTT TTCTGAAGGA ACCAATCTTA AACATCCATG ACCTAACTCA GATCCACTCT 
GACATGAATC TCCCAGTCCC TGACCCCATT CTTCTCACCA ATAGCCATGA TGGACTGGAT 
GGTCCCACTT ATAAGAAGCG AAGGTTGGAT GAGTGTGAAG AAGCCTTCCA AGGAACCAAG 
GTGTTTGTGA TGCCCAATGG GATGCTGAAA AGCAACCAGC AGCTGGTGGA CATTATTGAG 
AAAGTGAAAC CTGAGATCCG GCTGTTGATT GAGAAATGTA ACACGCCTTC AGGCAAAGGT 
CCTCATATAT GTTTTGACCT CCAGGTCAAA ATGTGGGTAC AGCTCCTGAT TCCCAGGATA 
GAAGATGGAA ACAACTTTGG GGTGTCCATT CAGGAGGAAA CAGTTGCAGA GCTAAGAACT 
GTTGAGAGTG AAGCTGCATC TTATCTGGAC CAGATTTCTA GATATTATAT TACAAGAGCC 
AAATTGGTTT CTAAAATAGC TAAATATCCC CATGTGGAGG ACTATCGCCG CACCGTGACA 
GAGATTGATG AGAAAGAATA TATCAGCCTT CGGCTCATCA TATCAGAGCT GAGGAATCAA 
TATGTCACTC TACATGACAT GATCCTGAAA AATATCGAGA AGATCAAACG GCCCCGGAGC 
AGCAATGCAG AGACTCTGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSME3 ( NM_176863.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_789839.1 Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07985
Clone ID Related Accession (Same CDS sequence)	NM_176863.3 , NM_176863.2
Accession Version	NM_176863.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 804bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-10-20
Organism	Homo sapiens(human)
Product	proteasome activator complex subunit 3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC016889.28, U11292.1 and AI304773.1. On May 26, 2012 this sequence version replaced NM_176863.1. Transcript Variant: This variant (2), uses ans alternate in-frame splice site, compared to variant 1. The resulting isoform (2) is longer than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U11292.1, SRR1803617.227537.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCGT TGCTGAAGGT GGATCAGGAA GTGAAGCTCA AGGTTGATTC TTTCAGGGAG 
CGGATCACAA GTGAGGCAGA AGACTTGGTG GCAAATTTTT TCCCAAAGAA GTTATTAGAA 
CTTGATAGTT TTCTGAAGGA ACCAATCTTA AACATCCATG ACCTAACTCA GATCCACTCT 
GACATGAATC TCCCAGTCCC TGACCCCATT CTTCTCACCA ATAGCCATGA TGGACTGGAT 
GGTCCCACTT ATAAGAAGCG AAGGTTGGAT GAGTGTGAAG AAGCCTTCCA AGGAACCAAG 
GTGTTTGTGA TGCCCAATGG GATGCTGAAA AGCAACCAGC AGCTGGTGGA CATTATTGAG 
AAAGTGAAAC CTGAGATCCG GCTGTTGATT GAGAAATGTA ACACGCCTTC AGGCAAAGGT 
CCTCATATAT GTTTTGACCT CCAGGTCAAA ATGTGGGTAC AGCTCCTGAT TCCCAGGATA 
GAAGATGGAA ACAACTTTGG GGTGTCCATT CAGGAGGAAA CAGTTGCAGA GCTAAGAACT 
GTTGAGAGTG AAGCTGCATC TTATCTGGAC CAGATTTCTA GATATTATAT TACAAGAGCC 
AAATTGGTTT CTAAAATAGC TAAATATCCC CATGTGGAGG ACTATCGCCG CACCGTGACA 
GAGATTGATG AGAAAGAATA TATCAGCCTT CGGCTCATCA TATCAGAGCT GAGGAATCAA 
TATGTCACTC TACATGACAT GATCCTGAAA AATATCGAGA AGATCAAACG GCCCCGGAGC 
AGCAATGCAG AGACTCTGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_789839.1
CDS	491..1294
Translation	MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTPSGKGPHICFDLQVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY

Target ORF information:

RefSeq Version	NM_176863.2
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176863.2

ORF Insert Sequence:

ATGGCCTCGT TGCTGAAGGT GGATCAGGAA GTGAAGCTCA AGGTTGATTC TTTCAGGGAG 
CGGATCACAA GTGAGGCAGA AGACTTGGTG GCAAATTTTT TCCCAAAGAA GTTATTAGAA 
CTTGATAGTT TTCTGAAGGA ACCAATCTTA AACATCCATG ACCTAACTCA GATCCACTCT 
GACATGAATC TCCCAGTCCC TGACCCCATT CTTCTCACCA ATAGCCATGA TGGACTGGAT 
GGTCCCACTT ATAAGAAGCG AAGGTTGGAT GAGTGTGAAG AAGCCTTCCA AGGAACCAAG 
GTGTTTGTGA TGCCCAATGG GATGCTGAAA AGCAACCAGC AGCTGGTGGA CATTATTGAG 
AAAGTGAAAC CTGAGATCCG GCTGTTGATT GAGAAATGTA ACACGCCTTC AGGCAAAGGT 
CCTCATATAT GTTTTGACCT CCAGGTCAAA ATGTGGGTAC AGCTCCTGAT TCCCAGGATA 
GAAGATGGAA ACAACTTTGG GGTGTCCATT CAGGAGGAAA CAGTTGCAGA GCTAAGAACT 
GTTGAGAGTG AAGCTGCATC TTATCTGGAC CAGATTTCTA GATATTATAT TACAAGAGCC 
AAATTGGTTT CTAAAATAGC TAAATATCCC CATGTGGAGG ACTATCGCCG CACCGTGACA 
GAGATTGATG AGAAAGAATA TATCAGCCTT CGGCTCATCA TATCAGAGCT GAGGAATCAA 
TATGTCACTC TACATGACAT GATCCTGAAA AATATCGAGA AGATCAAACG GCCCCGGAGC 
AGCAATGCAG AGACTCTGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSME3 ( NM_001267045.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001253974.1 Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu08462
Clone ID Related Accession (Same CDS sequence)	NM_001267045.1 , NM_001267045.2
Accession Version	NM_001267045.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-10-20
Organism	Homo sapiens(human)
Product	proteasome activator complex subunit 3 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI464061.1, BX640801.1, AC016889.28 and AI304773.1. Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is longer than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX640801.1, SRR1803614.182586.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAAAAT GGATCCTCAA AAAAATAAAG TATTTGCAGT CTGGGGGCCT CTCAGCTTCT 
TATTACAGTT ACAAGGTTGA TTCTTTCAGG GAGCGGATCA CAAGTGAGGC AGAAGACTTG 
GTGGCAAATT TTTTCCCAAA GAAGTTATTA GAACTTGATA GTTTTCTGAA GGAACCAATC 
TTAAACATCC ATGACCTAAC TCAGATCCAC TCTGACATGA ATCTCCCAGT CCCTGACCCC 
ATTCTTCTCA CCAATAGCCA TGATGGACTG GATGGTCCCA CTTATAAGAA GCGAAGGTTG 
GATGAGTGTG AAGAAGCCTT CCAAGGAACC AAGGTGTTTG TGATGCCCAA TGGGATGCTG 
AAAAGCAACC AGCAGCTGGT GGACATTATT GAGAAAGTGA AACCTGAGAT CCGGCTGTTG 
ATTGAGAAAT GTAACACGGT CAAAATGTGG GTACAGCTCC TGATTCCCAG GATAGAAGAT 
GGAAACAACT TTGGGGTGTC CATTCAGGAG GAAACAGTTG CAGAGCTAAG AACTGTTGAG 
AGTGAAGCTG CATCTTATCT GGACCAGATT TCTAGATATT ATATTACAAG AGCCAAATTG 
GTTTCTAAAA TAGCTAAATA TCCCCATGTG GAGGACTATC GCCGCACCGT GACAGAGATT 
GATGAGAAAG AATATATCAG CCTTCGGCTC ATCATATCAG AGCTGAGGAA TCAATATGTC 
ACTCTACATG ACATGATCCT GAAAAATATC GAGAAGATCA AACGGCCCCG GAGCAGCAAT 
GCAGAGACTC TGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001253974.1
CDS	785..1582
Translation	MEKWILKKIKYLQSGGLSASYYSYKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY

Target ORF information:

RefSeq Version	NM_001267045.1
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267045.1

ORF Insert Sequence:

ATGGAAAAAT GGATCCTCAA AAAAATAAAG TATTTGCAGT CTGGGGGCCT CTCAGCTTCT 
TATTACAGTT ACAAGGTTGA TTCTTTCAGG GAGCGGATCA CAAGTGAGGC AGAAGACTTG 
GTGGCAAATT TTTTCCCAAA GAAGTTATTA GAACTTGATA GTTTTCTGAA GGAACCAATC 
TTAAACATCC ATGACCTAAC TCAGATCCAC TCTGACATGA ATCTCCCAGT CCCTGACCCC 
ATTCTTCTCA CCAATAGCCA TGATGGACTG GATGGTCCCA CTTATAAGAA GCGAAGGTTG 
GATGAGTGTG AAGAAGCCTT CCAAGGAACC AAGGTGTTTG TGATGCCCAA TGGGATGCTG 
AAAAGCAACC AGCAGCTGGT GGACATTATT GAGAAAGTGA AACCTGAGAT CCGGCTGTTG 
ATTGAGAAAT GTAACACGGT CAAAATGTGG GTACAGCTCC TGATTCCCAG GATAGAAGAT 
GGAAACAACT TTGGGGTGTC CATTCAGGAG GAAACAGTTG CAGAGCTAAG AACTGTTGAG 
AGTGAAGCTG CATCTTATCT GGACCAGATT TCTAGATATT ATATTACAAG AGCCAAATTG 
GTTTCTAAAA TAGCTAAATA TCCCCATGTG GAGGACTATC GCCGCACCGT GACAGAGATT 
GATGAGAAAG AATATATCAG CCTTCGGCTC ATCATATCAG AGCTGAGGAA TCAATATGTC 
ACTCTACATG ACATGATCCT GAAAAATATC GAGAAGATCA AACGGCCCCG GAGCAGCAAT 
GCAGAGACTC TGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSME3 ( NM_001267045.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001253974.1 Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu08462
Clone ID Related Accession (Same CDS sequence)	NM_001267045.1 , NM_001267045.2
Accession Version	NM_001267045.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	proteasome activator complex subunit 3 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI464061.1, BX640801.1, AC016889.28 and AI304773.1. On May 31, 2019 this sequence version replaced NM_001267045.1. Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is longer than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.182586.1, BX640801.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAAAAT GGATCCTCAA AAAAATAAAG TATTTGCAGT CTGGGGGCCT CTCAGCTTCT 
TATTACAGTT ACAAGGTTGA TTCTTTCAGG GAGCGGATCA CAAGTGAGGC AGAAGACTTG 
GTGGCAAATT TTTTCCCAAA GAAGTTATTA GAACTTGATA GTTTTCTGAA GGAACCAATC 
TTAAACATCC ATGACCTAAC TCAGATCCAC TCTGACATGA ATCTCCCAGT CCCTGACCCC 
ATTCTTCTCA CCAATAGCCA TGATGGACTG GATGGTCCCA CTTATAAGAA GCGAAGGTTG 
GATGAGTGTG AAGAAGCCTT CCAAGGAACC AAGGTGTTTG TGATGCCCAA TGGGATGCTG 
AAAAGCAACC AGCAGCTGGT GGACATTATT GAGAAAGTGA AACCTGAGAT CCGGCTGTTG 
ATTGAGAAAT GTAACACGGT CAAAATGTGG GTACAGCTCC TGATTCCCAG GATAGAAGAT 
GGAAACAACT TTGGGGTGTC CATTCAGGAG GAAACAGTTG CAGAGCTAAG AACTGTTGAG 
AGTGAAGCTG CATCTTATCT GGACCAGATT TCTAGATATT ATATTACAAG AGCCAAATTG 
GTTTCTAAAA TAGCTAAATA TCCCCATGTG GAGGACTATC GCCGCACCGT GACAGAGATT 
GATGAGAAAG AATATATCAG CCTTCGGCTC ATCATATCAG AGCTGAGGAA TCAATATGTC 
ACTCTACATG ACATGATCCT GAAAAATATC GAGAAGATCA AACGGCCCCG GAGCAGCAAT 
GCAGAGACTC TGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001253974.1
CDS	530..1327
Translation	MEKWILKKIKYLQSGGLSASYYSYKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTVKMWVQLLIPRIEDGNNFGVSIQEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDYRRTVTEIDEKEYISLRLIISELRNQYVTLHDMILKNIEKIKRPRSSNAETLY

Target ORF information:

RefSeq Version	NM_001267045.2
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome activator subunit 3 (PSME3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267045.2

ORF Insert Sequence:

ATGGAAAAAT GGATCCTCAA AAAAATAAAG TATTTGCAGT CTGGGGGCCT CTCAGCTTCT 
TATTACAGTT ACAAGGTTGA TTCTTTCAGG GAGCGGATCA CAAGTGAGGC AGAAGACTTG 
GTGGCAAATT TTTTCCCAAA GAAGTTATTA GAACTTGATA GTTTTCTGAA GGAACCAATC 
TTAAACATCC ATGACCTAAC TCAGATCCAC TCTGACATGA ATCTCCCAGT CCCTGACCCC 
ATTCTTCTCA CCAATAGCCA TGATGGACTG GATGGTCCCA CTTATAAGAA GCGAAGGTTG 
GATGAGTGTG AAGAAGCCTT CCAAGGAACC AAGGTGTTTG TGATGCCCAA TGGGATGCTG 
AAAAGCAACC AGCAGCTGGT GGACATTATT GAGAAAGTGA AACCTGAGAT CCGGCTGTTG 
ATTGAGAAAT GTAACACGGT CAAAATGTGG GTACAGCTCC TGATTCCCAG GATAGAAGAT 
GGAAACAACT TTGGGGTGTC CATTCAGGAG GAAACAGTTG CAGAGCTAAG AACTGTTGAG 
AGTGAAGCTG CATCTTATCT GGACCAGATT TCTAGATATT ATATTACAAG AGCCAAATTG 
GTTTCTAAAA TAGCTAAATA TCCCCATGTG GAGGACTATC GCCGCACCGT GACAGAGATT 
GATGAGAAAG AATATATCAG CCTTCGGCTC ATCATATCAG AGCTGAGGAA TCAATATGTC 
ACTCTACATG ACATGATCCT GAAAAATATC GAGAAGATCA AACGGCCCCG GAGCAGCAAT 
GCAGAGACTC TGTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Knockdown of REG? inhibits the proliferation and migration and promotes the apoptosis of multiple myeloma cells by downregulating NF-?B signal pathway.
Hematology (Amsterdam, Netherlands)1-7(2017 Oct)
Liu S,Zheng LL,Zhu YM,Shen HJ,Zhong Q,Huang J,Li C,Liu Z,Yao MD,Ou RM,Zhang Q

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PSME3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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