Gene Symbol | NAT2 |
Entrez Gene ID | 10 |
Full Name | N-acetyltransferase 2 |
Synonyms | AAC2,NAT-2,PNAT |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(Human) |
Genome | |
Summary | This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | [Acetylation, slow], 243400 (3) |