CBFA2T2 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	CBFA2T2
Entrez Gene ID	419155
Full Name	CBFA2/RUNX1 translocation partner 2
Synonyms	MTGR1
General protein information	Preferred Names CBFA2/RUNX1 translocation partner 2 Names protein CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 myeloid translocation gene-related protein 1
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001011689.1	NP_001011689.1	protein CBFA2T2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cbfa2t2	NP_001162014.1
Xenopus tropicalis (tropical clawed frog)	cbfa2t2	NP_001096296.1
	CBFA2T2	XP_001103894.1
Mus musculus (house mouse)	Cbfa2t2	NP_766448.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010867	XP_309838.4
Homo sapiens (human)	CBFA2T2	NP_001028171.1
Canis lupus familiaris (dog)	CBFA2T2	XP_005634998.1
Bos taurus (cattle)	CBFA2T2	XP_002692347.3
Pan troglodytes (chimpanzee)	CBFA2T2	XP_001158443.2
Gallus gallus (chicken)	CBFA2T2	NP_001011689.1

Gene Ontology
Bibliography

Related articles in PubMed

Interaction of MTG family proteins with NEUROG2 and ASCL1 in the developing nervous system.
Aaker JD, Patineau AL, Yang HJ, Ewart DT, Nakagawa Y, McLoon SC, Koyano-Nakagawa N
Neuroscience letters474(1)46-51(2010 Apr)

Feedback regulation of NEUROG2 activity by MTGR1 is required for progression of neurogenesis.
Aaker JD, Patineau AL, Yang HJ, Ewart DT, Gong W, Li T, Nakagawa Y, McLoon SC, Koyano-Nakagawa N
Molecular and cellular neurosciences42(4)267-77(2009 Dec)

The expression and function of MTG/ETO family proteins during neurogenesis.
Koyano-Nakagawa N, Kintner C
Developmental biology278(1)22-34(2005 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

MTGR1 binds NEUROG2 and ASCL1 using multiple interaction surfaces, and all conserved domains are required for its repressor activity.
Title: Interaction of MTG family proteins with NEUROG2 and ASCL1 in the developing nervous system.

Data show that MTGR1 physically interacts with NEUROG2 and represses transcriptional activity of NEUROG2.
Title: Feedback regulation of NEUROG2 activity by MTGR1 is required for progression of neurogenesis.

The following CBFA2T2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CBFA2T2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa25827	NM_001011689.1 Latest version!	Gallus gallus CBFA2/RUNX1 partner transcriptional co-repressor 2 (CBFA2T2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CBFA2T2 ( NM_001011689.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001011689.1 Gallus gallus CBFA2/RUNX1 partner transcriptional co-repressor 2 (CBFA2T2), mRNA.

Price & Availability↑

CloneID	OGa25827
Clone ID Related Accession (Same CDS sequence)	NM_001011689.1
Accession Version	NM_001011689.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1755bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Gallus gallus(chicken)
Product	protein CBFA2T2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY714076.1. On Feb 7, 2005 this sequence version replaced XM_417339.1. ##Evidence-Data-START## Transcript exon combination :: AY714076.1 [ECO:0000332] ##Evidence-Data-END##

ATGGTGGGGA TCTCGGGAGG CTGCCAGTTT GCTGGTGAGA AGAGGGTGCC AGTGATGCCC 
GGCTCGCCCG TGGAAGTGAA GATACAGACC AGGTCCTCTC CTCCCAACAT GCCACCACTG 
CCCCCCGTCA ACCCCGGCGG CCCCCGGCCC GTCTCCTTCA CCCCAACTGC ACTGCCCAAC 
GGGATGAACC ATTCCCCCCC AACGCTCAAC GGGGCACCGT CCCCACCCCA GCGCTTTGGC 
AACGGCCCGG CCTCCTCCTC CTCTTCCTCA CTGACCAACC AGCAGCTCCC GGCCACGTGC 
GGTGCGCGGC AGCTCAGCAA GCTGAAACGC TTCCTCACCA CCCTGCAGCA GTTTGGCAAT 
GACATCTCTC CGGAGATCGG GGAGAAGGTG CGGACCCTGG TCCTGGCCCT GGTGAACTCA 
ACAGTGACGA TTGAGGAATT TCACTGCAAG CTGCAAGAGG CGACGAACTT CCCCCTGCGG 
CCCTTTGTGA TCCCCTTCCT GAAGGCCAAC CTCCCTCTGC TCCAGAGAGA GCTGCTGCAC 
TGCGCCCGGG CTGCCAAGCA GACACCATCC CAGTACCTGG CCCAGCATGA GCACATCCTT 
CTCAACACCA CCTCCTCCCC AGCCGACTCC TCGGAGCTGC TCATTGAGGT CAACGGGAAC 
GGCAAGAGGC ACAGCCCTGA CAGAAGGGAT GATAACAGCT TCGAGAGGGA GCCGCTGCCG 
ACGGAGCCGC CGGCCAAGCG TGTGTGCACC ATCAGCCCTG CGCCCCGGCA CAGCCCAGCA 
CTCAGCATCC CAATGCTGAA CCCCGGCGGG CAGTTCCACC CCACCCCACC ACCCCTCCAG 
CACTACACCC TGGAAGACAT CGCCACCTCC CATCTGTACA GAGACCCCGG CAAGATGCTG 
GAGCACAGGG AGATCCGGGA CAGGCACGGC GGGCTCGGTT TGAATGGAGG TTACCAGGAT 
GAGTTGGTGG ACCACCGCCT GACAGAGAGG GAGTGGGCTG ACGAGTGGAA GCACCTCGAT 
CATGCTCTGA ACTGCATCAT GGAGATGGTG GAGAAGACCC GGCGCTCCAT GGCCGTGCTG 
CGGCGCTGCC AGGAGGCCGA CCGTGAGGAG CTCAACTACT GGAAGAGGCG GTGCAGTGAG 
GCTGAGCCCC GCAAGGCGGG GGGGGAGTTG GGCACAGCCC GGCACAGCCC CGGCAGCTCC 
GACTCCATCG GCAGCGATTC ACTGCGGGAG TTCAGCAGCA GGTCGGGGCC GGGCTACGTC 
ACTGAGGAGA TATGGAAGAA AGCAGAAGAA GCCGTGAACG AGGTGAAGCG CCAGGCCATG 
TCGGAGGTGC AGAAGGCCGT GGCAGAGGCA GAGCAGAAGG CGTTTGAGAT GATCGCCTCC 
GAGAGGGCGC GCATGGAGCA GACCATCGCC GACGCCAAGC GTCAGGCCAC CGAGGATGCT 
TTCCTGGTGA TCAACGAGCA GGAGGAGTCC ACGGAGAGCT GCTGGAACTG CGGCCGTAAG 
GCCAGTGAGA CGTGCAGCGG CTGCAACATC GCGCGCTACT GCGGCTCCTT CTGCCAGCAC 
AAGGACTGGG AGAGGCACCA CCGCATCTGC GGGCAGAGCC TGCACGGCCA CAGCAAGGGG 
CTGGCACTGC CTGCGGGGCG CTCGGCCAAG GGCATGGATG GCGTGCCCAG CCCCAGCATG 
GAGAAGAGCT CGGCAGCCAC CTCCCGCTCC TCCACGCCCG CATTTGTGAC AGCGATAGAC 
ACGAACGGAC TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001011689.1
CDS	51..1805
Translation	MVGISGGCQFAGEKRVPVMPGSPVEVKIQTRSSPPNMPPLPPVNPGGPRPVSFTPTALPNGMNHSPPTLNGAPSPPQRFGNGPASSSSSSLTNQQLPATCGARQLSKLKRFLTTLQQFGNDISPEIGEKVRTLVLALVNSTVTIEEFHCKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARAAKQTPSQYLAQHEHILLNTTSSPADSSELLIEVNGNGKRHSPDRRDDNSFEREPLPTEPPAKRVCTISPAPRHSPALSIPMLNPGGQFHPTPPPLQHYTLEDIATSHLYRDPGKMLEHREIRDRHGGLGLNGGYQDELVDHRLTEREWADEWKHLDHALNCIMEMVEKTRRSMAVLRRCQEADREELNYWKRRCSEAEPRKAGGELGTARHSPGSSDSIGSDSLREFSSRSGPGYVTEEIWKKAEEAVNEVKRQAMSEVQKAVAEAEQKAFEMIASERARMEQTIADAKRQATEDAFLVINEQEESTESCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRICGQSLHGHSKGLALPAGRSAKGMDGVPSPSMEKSSAATSRSSTPAFVTAIDTNGL

Target ORF information:

RefSeq Version	NM_001011689.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus CBFA2/RUNX1 partner transcriptional co-repressor 2 (CBFA2T2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001011689.1

ORF Insert Sequence:

ATGGTGGGGA TCTCGGGAGG CTGCCAGTTT GCTGGTGAGA AGAGGGTGCC AGTGATGCCC 
GGCTCGCCCG TGGAAGTGAA GATACAGACC AGGTCCTCTC CTCCCAACAT GCCACCACTG 
CCCCCCGTCA ACCCCGGCGG CCCCCGGCCC GTCTCCTTCA CCCCAACTGC ACTGCCCAAC 
GGGATGAACC ATTCCCCCCC AACGCTCAAC GGGGCACCGT CCCCACCCCA GCGCTTTGGC 
AACGGCCCGG CCTCCTCCTC CTCTTCCTCA CTGACCAACC AGCAGCTCCC GGCCACGTGC 
GGTGCGCGGC AGCTCAGCAA GCTGAAACGC TTCCTCACCA CCCTGCAGCA GTTTGGCAAT 
GACATCTCTC CGGAGATCGG GGAGAAGGTG CGGACCCTGG TCCTGGCCCT GGTGAACTCA 
ACAGTGACGA TTGAGGAATT TCACTGCAAG CTGCAAGAGG CGACGAACTT CCCCCTGCGG 
CCCTTTGTGA TCCCCTTCCT GAAGGCCAAC CTCCCTCTGC TCCAGAGAGA GCTGCTGCAC 
TGCGCCCGGG CTGCCAAGCA GACACCATCC CAGTACCTGG CCCAGCATGA GCACATCCTT 
CTCAACACCA CCTCCTCCCC AGCCGACTCC TCGGAGCTGC TCATTGAGGT CAACGGGAAC 
GGCAAGAGGC ACAGCCCTGA CAGAAGGGAT GATAACAGCT TCGAGAGGGA GCCGCTGCCG 
ACGGAGCCGC CGGCCAAGCG TGTGTGCACC ATCAGCCCTG CGCCCCGGCA CAGCCCAGCA 
CTCAGCATCC CAATGCTGAA CCCCGGCGGG CAGTTCCACC CCACCCCACC ACCCCTCCAG 
CACTACACCC TGGAAGACAT CGCCACCTCC CATCTGTACA GAGACCCCGG CAAGATGCTG 
GAGCACAGGG AGATCCGGGA CAGGCACGGC GGGCTCGGTT TGAATGGAGG TTACCAGGAT 
GAGTTGGTGG ACCACCGCCT GACAGAGAGG GAGTGGGCTG ACGAGTGGAA GCACCTCGAT 
CATGCTCTGA ACTGCATCAT GGAGATGGTG GAGAAGACCC GGCGCTCCAT GGCCGTGCTG 
CGGCGCTGCC AGGAGGCCGA CCGTGAGGAG CTCAACTACT GGAAGAGGCG GTGCAGTGAG 
GCTGAGCCCC GCAAGGCGGG GGGGGAGTTG GGCACAGCCC GGCACAGCCC CGGCAGCTCC 
GACTCCATCG GCAGCGATTC ACTGCGGGAG TTCAGCAGCA GGTCGGGGCC GGGCTACGTC 
ACTGAGGAGA TATGGAAGAA AGCAGAAGAA GCCGTGAACG AGGTGAAGCG CCAGGCCATG 
TCGGAGGTGC AGAAGGCCGT GGCAGAGGCA GAGCAGAAGG CGTTTGAGAT GATCGCCTCC 
GAGAGGGCGC GCATGGAGCA GACCATCGCC GACGCCAAGC GTCAGGCCAC CGAGGATGCT 
TTCCTGGTGA TCAACGAGCA GGAGGAGTCC ACGGAGAGCT GCTGGAACTG CGGCCGTAAG 
GCCAGTGAGA CGTGCAGCGG CTGCAACATC GCGCGCTACT GCGGCTCCTT CTGCCAGCAC 
AAGGACTGGG AGAGGCACCA CCGCATCTGC GGGCAGAGCC TGCACGGCCA CAGCAAGGGG 
CTGGCACTGC CTGCGGGGCG CTCGGCCAAG GGCATGGATG GCGTGCCCAG CCCCAGCATG 
GAGAAGAGCT CGGCAGCCAC CTCCCGCTCC TCCACGCCCG CATTTGTGAC AGCGATAGAC 
ACGAACGGAC TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interaction of MTG family proteins with NEUROG2 and ASCL1 in the developing nervous system.
Neuroscience letters474(1)46-51(2010 Apr)
Aaker JD,Patineau AL,Yang HJ,Ewart DT,Nakagawa Y,McLoon SC,Koyano-Nakagawa N

Feedback regulation of NEUROG2 activity by MTGR1 is required for progression of neurogenesis.
Molecular and cellular neurosciences42(4)267-77(2009 Dec)
Aaker JD,Patineau AL,Yang HJ,Ewart DT,Gong W,Li T,Nakagawa Y,McLoon SC,Koyano-Nakagawa N

The expression and function of MTG/ETO family proteins during neurogenesis.
Developmental biology278(1)22-34(2005 Feb)
Koyano-Nakagawa N,Kintner C