CATH1 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	CATH1
Entrez Gene ID	414337
Full Name	cathelicidin-1
Synonyms	CATH-1,CATH-3,CATHL1
General protein information	Preferred Names cathelicidin-1 Names cathelicidin-1 cathelicidin antimicrobial peptide cathelicidin-3 fowlicidin-1
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001001605.3	NP_001001605.1	cathelicidin-1 precursor

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	CAMP	NP_001020001.2
Gallus gallus (chicken)	CATHL3	NP_001001605.1

Gene Ontology
Bibliography

Related articles in PubMed

Modulatory roles of proinflammatory cytokines on the expression of cathelicidins in the lower regions of the oviduct of laying hens.
Abdel-Mageed AM, Nii T, Isobe N, Yoshimura Y
Cytokine9966-72(2017 Nov)

Immune regulatory activities of fowlicidin-1, a cathelicidin host defense peptide.
Bommineni YR, Pham GH, Sunkara LT, Achanta M, Zhang G
Molecular immunology59(1)55-63(2014 May)

Lipopolysaccharide bound structures of the active fragments of fowlicidin-1, a cathelicidin family of antimicrobial and antiendotoxic peptide from chicken, determined by transferred nuclear Overhauser effect spectroscopy.
Bhunia A, Mohanram H, Bhattacharjya S
Biopolymers92(1)9-22(2009)

Chicken cathelicidin-B1, an antimicrobial guardian at the mucosal M cell gateway.
Goitsuka R, Chen CL, Benyon L, Asano Y, Kitamura D, Cooper MD
Proceedings of the National Academy of Sciences of the United States of America104(38)15063-8(2007 Sep)

Fowlicidin-3 is an alpha-helical cationic host defense peptide with potent antibacterial and lipopolysaccharide-neutralizing activities.
Bommineni YR, Dai H, Gong YX, Soulages JL, Fernando SC, Desilva U, Prakash O, Zhang G
The FEBS journal274(2)418-28(2007 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CATH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CATH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa00160	NM_001001605.3 Latest version!	Gallus gallus cathelicidin-1 (CATH1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CATH1 ( NM_001001605.3 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001001605.1 Gallus gallus cathelicidin-1 (CATH1), mRNA.

Price & Availability↑

CloneID	OGa00160
Clone ID Related Accession (Same CDS sequence)	NM_001001605.3
Accession Version	NM_001001605.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 447bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Gallus gallus(chicken)
Product	cathelicidin-1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BX936022.1. On Feb 23, 2013 this sequence version replaced NM_001001605.2. ##Evidence-Data-START## Transcript exon combination :: BX936022.1, BU106516.1 [ECO:0000332] ##Evidence-Data-END##

ATGCTGAGCT GCTGGGTGCT GCTGCTGGCG CTGCTGGGGG GGGCCTGCGC CCTCCCGGCC 
CCCCTGGGCT ACTCCCAGGC TCTGGCCCAG GCTGTGGACT CCTACAACCA ACGGCCTGAG 
GTGCAGAATG CCTTCCGGCT GCTCAGCGCC GACCCCGAGC CCGGCCCGAA CGTCCAGCTC 
AGCTCCCTGC ACAACCTCAA CTTCACCATC ATGGAGACGC GGTGCCAGGC GCGCTCGGGC 
GCCCAGCTGG ACAGCTGCGA GTTCAAGGAG GACGGGCTCG TCAAGGACTG CGCTGCGCCC 
GTGGTGCTGC AAGGCGGCCG CGCCGTGCTC GATGTCACCT GCGTGGACTC CATGGCTGAC 
CCTGTCCGCG TCAAGCGCGT CTGGCCGCTG GTCATCAGGA CTGTGATTGC AGGATACAAC 
CTCTACCGGG CGATCAAGAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001001605.1
CDS	263..709
Translation	MLSCWVLLLALLGGACALPAPLGYSQALAQAVDSYNQRPEVQNAFRLLSADPEPGPNVQLSSLHNLNFTIMETRCQARSGAQLDSCEFKEDGLVKDCAAPVVLQGGRAVLDVTCVDSMADPVRVKRVWPLVIRTVIAGYNLYRAIKKK

Target ORF information:

RefSeq Version	NM_001001605.3
Organism	Gallus gallus(chicken)
Definition	Gallus gallus cathelicidin-1 (CATH1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001001605.3

ORF Insert Sequence:

ATGCTGAGCT GCTGGGTGCT GCTGCTGGCG CTGCTGGGGG GGGCCTGCGC CCTCCCGGCC 
CCCCTGGGCT ACTCCCAGGC TCTGGCCCAG GCTGTGGACT CCTACAACCA ACGGCCTGAG 
GTGCAGAATG CCTTCCGGCT GCTCAGCGCC GACCCCGAGC CCGGCCCGAA CGTCCAGCTC 
AGCTCCCTGC ACAACCTCAA CTTCACCATC ATGGAGACGC GGTGCCAGGC GCGCTCGGGC 
GCCCAGCTGG ACAGCTGCGA GTTCAAGGAG GACGGGCTCG TCAAGGACTG CGCTGCGCCC 
GTGGTGCTGC AAGGCGGCCG CGCCGTGCTC GATGTCACCT GCGTGGACTC CATGGCTGAC 
CCTGTCCGCG TCAAGCGCGT CTGGCCGCTG GTCATCAGGA CTGTGATTGC AGGATACAAC 
CTCTACCGGG CGATCAAGAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Modulatory roles of proinflammatory cytokines on the expression of cathelicidins in the lower regions of the oviduct of laying hens.
Cytokine9966-72(2017 Nov)
Abdel-Mageed AM,Nii T,Isobe N,Yoshimura Y

Immune regulatory activities of fowlicidin-1, a cathelicidin host defense peptide.
Molecular immunology59(1)55-63(2014 May)
Bommineni YR,Pham GH,Sunkara LT,Achanta M,Zhang G

Lipopolysaccharide bound structures of the active fragments of fowlicidin-1, a cathelicidin family of antimicrobial and antiendotoxic peptide from chicken, determined by transferred nuclear Overhauser effect spectroscopy.
Biopolymers92(1)9-22(2009)
Bhunia A,Mohanram H,Bhattacharjya S

Chicken cathelicidin-B1, an antimicrobial guardian at the mucosal M cell gateway.
Proceedings of the National Academy of Sciences of the United States of America104(38)15063-8(2007 Sep)
Goitsuka R,Chen CL,Benyon L,Asano Y,Kitamura D,Cooper MD

Fowlicidin-3 is an alpha-helical cationic host defense peptide with potent antibacterial and lipopolysaccharide-neutralizing activities.
The FEBS journal274(2)418-28(2007 Jan)
Bommineni YR,Dai H,Gong YX,Soulages JL,Fernando SC,Desilva U,Prakash O,Zhang G

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CATH1 cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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