Gene Symbol | Trap1 |
Entrez Gene ID | 35559 |
Full Name | CG3152 gene product from transcript CG3152-RA |
Synonyms | AAN71071,CG3152,Dmel\CG3152,TRAP1,TRAP1dr,dtrap-1,trap1 |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
ORF » Species Summary » Drosophila melanogaster » Trap1 cDNA ORF clone
Gene Symbol | Trap1 |
Entrez Gene ID | 35559 |
Full Name | CG3152 gene product from transcript CG3152-RA |
Synonyms | AAN71071,CG3152,Dmel\CG3152,TRAP1,TRAP1dr,dtrap-1,trap1 |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_058091.3 | NP_477439.2 | Trap1, isoform A |
NM_001273797.1 | NP_001260726.1 | Trap1, isoform B |
Mus musculus (house mouse) | Trap1 | NP_080784.1 |
Gallus gallus (chicken) | TRAP1 | NP_001006175.1 |
Danio rerio (zebrafish) | trap1 | NP_001107097.1 |
Drosophila melanogaster (fruit fly) | Trap1 | NP_001260726.1 |
Caenorhabditis elegans (roundworm) | R151.7 | NP_741220.2 |
Pan troglodytes (chimpanzee) | TRAP1 | XP_001167908.1 |
TRAP1 | XP_001094589.2 | |
Canis lupus familiaris (dog) | TRAP1 | XP_005621672.1 |
Bos taurus (cattle) | TRAP1 | NP_001033764.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010691 | XP_311405.3 |
Homo sapiens (human) | TRAP1 | NP_057376.2 |
Rattus norvegicus (Norway rat) | Trap1 | NP_001034090.1 |
Danio rerio (zebrafish) | LOC101884569 | XP_005163784.1 |
Xenopus tropicalis (tropical clawed frog) | trap1 | XP_002932506.1 |
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Inhibition of the mitochondrial TRAP1 generates a retrograde cell protective signal from mitochondria to the nucleus in a FOXO-dependent manner.
Title: Tumor Necrosis Factor Receptor-associated Protein 1 (TRAP1) Mutation and TRAP1 Inhibitor Gamitrinib-triphenylphosphonium (G-TPP) Induce a Forkhead Box O (FOXO)-dependent Cell Protective Signal from Mitochondria.
these studies suggest that TRAP1 regulates healthspan, potentially through activation of the UPR(mt).
Title: Mitochondrial chaperone TRAP1 activates the mitochondrial UPR and extends healthspan in Drosophila.
TRAP1 rescues PINK1 loss-of-function phenotypes.
Title: TRAP1 rescues PINK1 loss-of-function phenotypes.
Loss of Trap1 results in a decrease in mitochondrial function and increased sensitivity to stress, and that its upregulation in neurons of Pink1 mutant rescues mitochondrial impairment.
Title: Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease.
The following Trap1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trap1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OFa09030 | |
Clone ID Related Accession (Same CDS sequence) | NM_058091.3 , NM_001273797.1 | |
Accession Version | NM_058091.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2076bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | Trap1, isoform A | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Nov 5, 2002 this sequence version replaced NM_058091.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGTCTGTAC GAGCGATGGG AGTGCTGGGC CAGGCGTGCC GCCTCGGTCG CTGTGCCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_477439.2 |
CDS | 276..2351 |
Translation |
Target ORF information:
Target ORF information:
|
NM_058091.3 |
1 | ATGTCTGTAC GAGCGATGGG AGTGCTGGGC CAGGCGTGCC GCCTCGGTCG CTGTGCCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OFa09030 | |
Clone ID Related Accession (Same CDS sequence) | NM_058091.3 , NM_001273797.1 | |
Accession Version | NM_001273797.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2076bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | Trap1, isoform B | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGTCTGTAC GAGCGATGGG AGTGCTGGGC CAGGCGTGCC GCCTCGGTCG CTGTGCCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001260726.1 |
CDS | 101..2176 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001273797.1 |
1 | ATGTCTGTAC GAGCGATGGG AGTGCTGGGC CAGGCGTGCC GCCTCGGTCG CTGTGCCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. |
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. |
Sequence finishing and mapping of Drosophila melanogaster heterochromatin. |
The Release 5.1 annotation of Drosophila melanogaster heterochromatin. |
Combined evidence annotation of transposable elements in genome sequences. |