Gene Symbol | r2d2 |
Entrez Gene ID | 34066 |
Full Name | CG7138 gene product from transcript CG7138-RA |
Synonyms | CG7138,Dmel\CG7138,R2D2,R2d2,cg7138 |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
ORF » Species Summary » Drosophila melanogaster » r2d2 cDNA ORF clone
Gene Symbol | r2d2 |
Entrez Gene ID | 34066 |
Full Name | CG7138 gene product from transcript CG7138-RA |
Synonyms | CG7138,Dmel\CG7138,R2D2,R2d2,cg7138 |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001298791.1 | NP_001285720.1 | r2d2, isoform C |
NM_135308.2 | NP_609152.1 | r2d2, isoform A |
NM_001169432.2 | NP_001162903.1 | r2d2, isoform B |
Drosophila melanogaster (fruit fly) | r2d2 | NP_609152.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009887 | XP_001238071.2 |
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Partial reconstitution of the RNAi response in human cells has been demonstrated using Drosophila gene products, DCR-2, Loqs-PD, and R2D2.
Title: Partial reconstitution of the RNAi response in human cells using Drosophila gene products.
R2D2 and Loqs-PD have partially overlapping function.
Title: Transposon defense by endo-siRNAs, piRNAs and somatic pilRNAs in Drosophila: contributions of Loqs-PD and R2D2.
R2D2 controls endo-siRNA sorting by localizing Dcr-2, and presumably endo-siRNA duplexes, to cytoplasmic foci.
Title: Roles of R2D2, a cytoplasmic D2 body component, in the endogenous siRNA pathway in Drosophila.
Propose that the Dicer-2 helicase domain uses ATP to generate many siRNAs from a single molecule of dsRNA and that phosphate and R2D2 restrict substrate specificity.
Title: Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease.
direct role for the R2D2/Dcr-2 heterodimer in sensing central mismatch positions that direct miRNA* strands to AGO2
Title: R2D2 organizes small regulatory RNA pathways in Drosophila.
The following r2d2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the r2d2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OFa14054 | |
Clone ID Related Accession (Same CDS sequence) | NM_001298791.1 , NM_135308.2 , NM_001169432.2 | |
Accession Version | NM_001298791.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | r2d2, isoform C | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGGATAACA AGTCAGCCGT ATCTGCTCTA CAGGAGTTTT GTGCCCGGAC ACAGATTAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001285720.1 |
CDS | 357..1292 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001298791.1 |
1 | ATGGATAACA AGTCAGCCGT ATCTGCTCTA CAGGAGTTTT GTGCCCGGAC ACAGATTAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OFa14054 | |
Clone ID Related Accession (Same CDS sequence) | NM_001298791.1 , NM_135308.2 , NM_001169432.2 | |
Accession Version | NM_135308.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | r2d2, isoform A | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jul 15, 2014 this sequence version replaced NM_135308.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGGATAACA AGTCAGCCGT ATCTGCTCTA CAGGAGTTTT GTGCCCGGAC ACAGATTAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_609152.1 |
CDS | 264..1199 |
Translation |
Target ORF information:
Target ORF information:
|
NM_135308.2 |
1 | ATGGATAACA AGTCAGCCGT ATCTGCTCTA CAGGAGTTTT GTGCCCGGAC ACAGATTAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OFa14054 | |
Clone ID Related Accession (Same CDS sequence) | NM_001298791.1 , NM_135308.2 , NM_001169432.2 | |
Accession Version | NM_001169432.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | r2d2, isoform B | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jul 15, 2014 this sequence version replaced NM_001169432.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGGATAACA AGTCAGCCGT ATCTGCTCTA CAGGAGTTTT GTGCCCGGAC ACAGATTAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001162903.1 |
CDS | 122..1057 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001169432.2 |
1 | ATGGATAACA AGTCAGCCGT ATCTGCTCTA CAGGAGTTTT GTGCCCGGAC ACAGATTAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. |
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. |
Sequence finishing and mapping of Drosophila melanogaster heterochromatin. |
The Release 5.1 annotation of Drosophila melanogaster heterochromatin. |
Combined evidence annotation of transposable elements in genome sequences. |