sc cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	sc
Entrez Gene ID	30982
Full Name	scute
Synonyms	AS-C T4,AS-C T4sc,CG3827,DROACS2,Dmel\CG3827,EG:198A6.1,Hw,SC_DA,Sc,T4,T4 AS-C,ascT4,bHLHc28,l(1)1Ba,sc/T4,scalpha,scute/sisterlessB,sis b,sis-b,sisB,sisb
General protein information	Preferred Names scute Names CG3827 gene product from transcript CG3827-RA Achaete/Scute CG3827-PA Hairy-wing achaete-scute asc sc-PA scute alpha scute-T4-transcript scute/sisterless-b sisterless-b
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: X Map Location: 1A8-1A8\|1-0.0 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_057455.3	NP_476803.1	scute

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000876	XP_316851.3
Drosophila melanogaster (fruit fly)	sc	NP_476803.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that bHLHb22 protein daughterless (Da) binding alters the turnover parameters of bHLHc28 protein scute (Sc).
Title: bHLH proteins involved in Drosophila neurogenesis are mutually regulated at the level of stability.

Proneural proteins Achaete and Scute associate with nuclear actin to promote formation of external sensory organs.
Title: Proneural proteins Achaete and Scute associate with nuclear actin to promote formation of external sensory organs.

quantified the relationship between achaete-scute complex (ASC) polymorphisms and bristle number phenotypes in several new population samples
Title: How repeatable are associations between polymorphisms in achaete-scute and bristle number variation in Drosophila?

achaete, but not scute, is dispensable for development of the peripheral nervous system of Drosophila.
Title: achaete, but not scute, is dispensable for the peripheral nervous system of Drosophila.

overexpression of chn enhances expression and the formation of extra sensory organs
Title: Charlatan, a Zn-finger transcription factor, establishes a novel level of regulation of the proneural achaete/scute genes of Drosophila.

The following sc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa00351	NM_057455.3 Latest version!	Drosophila melanogaster scute (sc), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

sc ( NM_057455.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_476803.1 Drosophila melanogaster scute (sc), mRNA.

Price & Availability↑

CloneID	OFa00351
Clone ID Related Accession (Same CDS sequence)	NM_057455.3
Accession Version	NM_057455.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1038bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	scute
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NC_004354). On Dec 17, 2009 this sequence version replaced NM_057455.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAAAAATA ATAATAATAC AACGAAAAGC ACTACCATGT CATCGAGTGT GCTGTCCACC 
AACGAAACGT TTCCAACGAC CATCAATTCG GCAACGAAGA TCTTTCGTTA TCAGCACATA 
ATGCCAGCCC CTAGTCCATT AATTCCCGGT GGCAATCAAA ATCAACCCGC TGGCACAATG 
CCAATTAAGA CTCGCAAGTA TACACCAAGG GGTATGGCAC TGACCAGATG CTCTGAATCA 
GTATCATCTC TATCGCCTGG TTCCTCGCCG GCTCCATATA ATGTAGACCA ATCCCAGTCG 
GTCCAAAGGC GCAATGCTAG AGAACGAAAT CGTGTAAAGC AGGTGAACAA CAGCTTCGCC 
AGGTTGCGGC AACATATACC ACAATCCATA ATCACGGATT TGACAAAGGG TGGTGGTCGA 
GGACCTCACA AAAAGATCTC CAAAGTAGAC ACACTGCGCA TTGCCGTCGA GTACATCCGG 
AGGCTTCAGG ATCTGGTGGA TGACCTAAAT GGGGGCAGCA ATATTGGTGC CAACAATGCA 
GTCACCCAGC TTCAACTTTG TTTGGATGAG TCCAGCAGTC ACAGTTCGAG CAGCAGTACT 
TGCAGTTCCT CAGGGCATAA TACCTACTAT CAAAACACGA TCTCTGTCAG TCCTCTGCAA 
CAACAGCAGC AGCTACAGAG GCAGCAGTTC AATCACCAAC CGCTGACAGC GCTCTCATTA 
AATACCAACT TGGTGGGCAC ATCCGTACCA GGTGGAGATG CAGGATGCGT ATCCACCAGC 
AAAAACCAGC AAACCTGCCA CTCGCCAACA TCATCATTCA ACTCCAGCAT GTCCTTTGAT 
TCAGGCACCT ACGAAGGAGT TCCCCAACAA ATATCCACCC ACCTGGATCG TCTGGATCAT 
CTGGACAACG AATTACACAC GCACTCCCAA CTTCAGCTAA AATTTGAACC GTACGAACAT 
TTTCAATTAG ACGAGGAGGA CTGCACCCCC GACGACGAGG AGATTTTGGA CTACATCTCT 
CTATGGCAGG AGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_476803.1
CDS	118..1155
Translation	MKNNNNTTKSTTMSSSVLSTNETFPTTINSATKIFRYQHIMPAPSPLIPGGNQNQPAGTMPIKTRKYTPRGMALTRCSESVSSLSPGSSPAPYNVDQSQSVQRRNARERNRVKQVNNSFARLRQHIPQSIITDLTKGGGRGPHKKISKVDTLRIAVEYIRRLQDLVDDLNGGSNIGANNAVTQLQLCLDESSSHSSSSSTCSSSGHNTYYQNTISVSPLQQQQQLQRQQFNHQPLTALSLNTNLVGTSVPGGDAGCVSTSKNQQTCHSPTSSFNSSMSFDSGTYEGVPQQISTHLDRLDHLDNELHTHSQLQLKFEPYEHFQLDEEDCTPDDEEILDYISLWQEQ

Target ORF information:

RefSeq Version	NM_057455.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster scute (sc), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_057455.3

ORF Insert Sequence:

ATGAAAAATA ATAATAATAC AACGAAAAGC ACTACCATGT CATCGAGTGT GCTGTCCACC 
AACGAAACGT TTCCAACGAC CATCAATTCG GCAACGAAGA TCTTTCGTTA TCAGCACATA 
ATGCCAGCCC CTAGTCCATT AATTCCCGGT GGCAATCAAA ATCAACCCGC TGGCACAATG 
CCAATTAAGA CTCGCAAGTA TACACCAAGG GGTATGGCAC TGACCAGATG CTCTGAATCA 
GTATCATCTC TATCGCCTGG TTCCTCGCCG GCTCCATATA ATGTAGACCA ATCCCAGTCG 
GTCCAAAGGC GCAATGCTAG AGAACGAAAT CGTGTAAAGC AGGTGAACAA CAGCTTCGCC 
AGGTTGCGGC AACATATACC ACAATCCATA ATCACGGATT TGACAAAGGG TGGTGGTCGA 
GGACCTCACA AAAAGATCTC CAAAGTAGAC ACACTGCGCA TTGCCGTCGA GTACATCCGG 
AGGCTTCAGG ATCTGGTGGA TGACCTAAAT GGGGGCAGCA ATATTGGTGC CAACAATGCA 
GTCACCCAGC TTCAACTTTG TTTGGATGAG TCCAGCAGTC ACAGTTCGAG CAGCAGTACT 
TGCAGTTCCT CAGGGCATAA TACCTACTAT CAAAACACGA TCTCTGTCAG TCCTCTGCAA 
CAACAGCAGC AGCTACAGAG GCAGCAGTTC AATCACCAAC CGCTGACAGC GCTCTCATTA 
AATACCAACT TGGTGGGCAC ATCCGTACCA GGTGGAGATG CAGGATGCGT ATCCACCAGC 
AAAAACCAGC AAACCTGCCA CTCGCCAACA TCATCATTCA ACTCCAGCAT GTCCTTTGAT 
TCAGGCACCT ACGAAGGAGT TCCCCAACAA ATATCCACCC ACCTGGATCG TCTGGATCAT 
CTGGACAACG AATTACACAC GCACTCCCAA CTTCAGCTAA AATTTGAACC GTACGAACAT 
TTTCAATTAG ACGAGGAGGA CTGCACCCCC GACGACGAGG AGATTTTGGA CTACATCTCT 
CTATGGCAGG AGCAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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sc cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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