DLA-DMB cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	DLA-DMB
Entrez Gene ID	607827
Full Name	major histocompatibility complex, class II, DM beta
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001271070.1	NP_001257999.1	major histocompatibility complex, class II, DM beta precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	BOLA-DMB	NP_001035571.1
Pan troglodytes (chimpanzee)	PATR-DMB	NP_001127814.1
Mus musculus (house mouse)	H2-DMb1	NP_034517.2
Homo sapiens (human)	HLA-DMB	NP_002109.2
Canis lupus familiaris (dog)	DLA-DMB	NP_001257999.1
Gallus gallus (chicken)	BMA2	NP_001128638.1
Xenopus tropicalis (tropical clawed frog)	LOC100495183	XP_002942059.1
	MAMU-DMB	XP_002803734.1
Mus musculus (house mouse)	H2-DMb2	NP_034518.1

Gene Ontology
Bibliography

Related articles in PubMed

Genomic sequence of the class II region of the canine MHC: comparison with the MHC of other mammalian species.
Debenham SL, Hart EA, Ashurst JL, Howe KL, Quail MA, Ollier WE, Binns MM
Genomics85(1)48-59(2005 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DLA-DMB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DLA-DMB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe33690	NM_001271070.1 Latest version!	Canis lupus familiaris major histocompatibility complex, class II, DM beta (DLA-DMB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DLA-DMB ( NM_001271070.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001257999.1 Canis lupus familiaris major histocompatibility complex, class II, DM beta (DLA-DMB), mRNA.

Price & Availability↑

CloneID	OCe33690
Clone ID Related Accession (Same CDS sequence)	NM_001271070.1
Accession Version	NM_001271070.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 792bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-22
Organism	Canis lupus familiaris(dog)
Product	major histocompatibility complex, class II, DM beta precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN392267.1 and DN365678.1. On Aug 31, 2012 this sequence version replaced XM_844644.2. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN07419814 [ECO:0000348] ##Evidence-Data-END##

ATGACCACAC TCCTACCATT GCTGCTGGGC CTCAGTCTGG GCTCTACCGG AGAAGGTGGC 
TTTATAGCTC ACGTGGAAAG CTCCTGTCTG TTGGATGATG ATGGGACTCC AAAGGATTTC 
ACATATTGTG TCTCCTTCAA TAAGGATTTG CTGACCTGCT GGGATCCAGA TGAGGCCAAA 
ATGGTCCCTT ATGAATTTGG GACACTGAAT GTCTTGGCCA ATTACCTCTC AGATTACCTC 
AACCAACAGG AATACCTGCA CCAGCGCTTG TCTAATGGGC TCCAGGACTG TGCCACACAT 
ACCCAGTCCT TCTGGGGATC ACTGACCCAC AGAACACGAC CACCAACTGT ACAAGTAGCC 
AAATCCACTC CTTTTAACAC GAAGGAGAGT GTGATGCTGG CCTGCTACGT GTGGGGCTTC 
TATCCAGCTG ATGTGACCAT CTCATGGAGG AAGAATGGGC AGCCTGTCCC TTCTCACAGT 
AGTGCCCTTA ATATGGCCCA GCCCAATGGA GACTGGACAT ATCAGACTGT CTCCCATCTA 
GCTACAACCC CTTCTTATGA GGATACCTAC ACCTGTGTTG TGGAGCACAT CGGGGCCCCT 
GAGCCTGTTT GTGAGGACTG GACACCTGGG CTGTCCCCAA TGCAGATAGT GAAGGTTTCT 
GTGTCTGGAG TGACTCTGGG CCTGGGCTTC ATCATCTTCT CTCTTGGTTT GCTCAGCTGG 
CGGAGAGCTG GCTCCTCTGG CTATGTTTTT CTCCCTGGAA CCAGTTATCC AGAAGGTCAA 
CATGTCTCCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257999.1
CDS	106..897
Translation	MTTLLPLLLGLSLGSTGEGGFIAHVESSCLLDDDGTPKDFTYCVSFNKDLLTCWDPDEAKMVPYEFGTLNVLANYLSDYLNQQEYLHQRLSNGLQDCATHTQSFWGSLTHRTRPPTVQVAKSTPFNTKESVMLACYVWGFYPADVTISWRKNGQPVPSHSSALNMAQPNGDWTYQTVSHLATTPSYEDTYTCVVEHIGAPEPVCEDWTPGLSPMQIVKVSVSGVTLGLGFIIFSLGLLSWRRAGSSGYVFLPGTSYPEGQHVS

Target ORF information:

RefSeq Version	NM_001271070.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris major histocompatibility complex, class II, DM beta (DLA-DMB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271070.1

ORF Insert Sequence:

ATGACCACAC TCCTACCATT GCTGCTGGGC CTCAGTCTGG GCTCTACCGG AGAAGGTGGC 
TTTATAGCTC ACGTGGAAAG CTCCTGTCTG TTGGATGATG ATGGGACTCC AAAGGATTTC 
ACATATTGTG TCTCCTTCAA TAAGGATTTG CTGACCTGCT GGGATCCAGA TGAGGCCAAA 
ATGGTCCCTT ATGAATTTGG GACACTGAAT GTCTTGGCCA ATTACCTCTC AGATTACCTC 
AACCAACAGG AATACCTGCA CCAGCGCTTG TCTAATGGGC TCCAGGACTG TGCCACACAT 
ACCCAGTCCT TCTGGGGATC ACTGACCCAC AGAACACGAC CACCAACTGT ACAAGTAGCC 
AAATCCACTC CTTTTAACAC GAAGGAGAGT GTGATGCTGG CCTGCTACGT GTGGGGCTTC 
TATCCAGCTG ATGTGACCAT CTCATGGAGG AAGAATGGGC AGCCTGTCCC TTCTCACAGT 
AGTGCCCTTA ATATGGCCCA GCCCAATGGA GACTGGACAT ATCAGACTGT CTCCCATCTA 
GCTACAACCC CTTCTTATGA GGATACCTAC ACCTGTGTTG TGGAGCACAT CGGGGCCCCT 
GAGCCTGTTT GTGAGGACTG GACACCTGGG CTGTCCCCAA TGCAGATAGT GAAGGTTTCT 
GTGTCTGGAG TGACTCTGGG CCTGGGCTTC ATCATCTTCT CTCTTGGTTT GCTCAGCTGG 
CGGAGAGCTG GCTCCTCTGG CTATGTTTTT CTCCCTGGAA CCAGTTATCC AGAAGGTCAA 
CATGTCTCCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genomic sequence of the class II region of the canine MHC: comparison with the MHC of other mammalian species.
Genomics85(1)48-59(2005 Jan)
Debenham SL,Hart EA,Ashurst JL,Howe KL,Quail MA,Ollier WE,Binns MM