GUCY2D cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	GUCY2D
Entrez Gene ID	403863
Full Name	guanylate cyclase 2D, retinal
General protein information	Preferred Names guanylate cyclase 2D, retinal Names retinal guanylyl cyclase 1 GC-E RETGC-1 ROS-GC guanylate cyclase E rod outer segment membrane guanylate cyclase
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003207.1	NP_001003207.1	retinal guanylyl cyclase 1 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Gucy2e	NP_077356.1
Xenopus tropicalis (tropical clawed frog)	gucy2d	XP_002942678.2
	GUCY2D	XP_001111670.1
Danio rerio (zebrafish)	gc3	NP_571941.1
Bos taurus (cattle)	GUCY2D	NP_776973.2
Homo sapiens (human)	GUCY2D	NP_000171.1
Pan troglodytes (chimpanzee)	GUCY2D	XP_003315414.1
Canis lupus familiaris (dog)	GUCY2D	NP_001003207.1
Mus musculus (house mouse)	Gucy2e	NP_032218.2

Gene Ontology
Bibliography

Related articles in PubMed

Organization of the canine gene encoding the E isoform of retinal guanylate cyclase (cGC-E) and exclusion of its involvement in the inherited retinal dystrophy of the Swedish Briard and Briard-beagle dogs.
Veske A, Nilsson SE, Gal A
Biochimica et biophysica acta1372(1)69-77(1998 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GUCY2D gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GUCY2D cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe00063	NM_001003207.1 Latest version!	Canis lupus familiaris guanylate cyclase 2D, retinal (GUCY2D), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$629.30 $899.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GUCY2D ( NM_001003207.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001003207.1 Canis lupus familiaris guanylate cyclase 2D, retinal (GUCY2D), mRNA.

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CloneID	OCe00063
Clone ID Related Accession (Same CDS sequence)	NM_001003207.1
Accession Version	NM_001003207.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3330bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-14
Organism	Canis lupus familiaris(dog)
Product	retinal guanylyl cyclase 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y15483.1. On Jan 12, 2005 this sequence version replaced XM_536629.1. ##Evidence-Data-START## Transcript exon combination :: Y15483.1 [ECO:0000332] ##Evidence-Data-END##

ATGAGCGCGT GCGCCCTCCT GGCGGGTGGG CTCCCCGACC CCCGGCTCTG CGCCCCCGCG 
CGGTGGGCTC GGTCCCCGCC CGGCGTCCCC GGGGCCCCGC CCTGGCCCCA GCCCCGGCTC 
CGGCTCCTGC TGCTGCTGCT CCTCCTGCCG CCCTCCGCCC TCTCCGCCGT CTTCACAGTC 
GGGGTGCTGG GCCCCTGGGC CTGCGACCCC ATCTTCGCCC GCGCCCGCCC GGACCTGGCC 
GCCCGCCTGG CCGCCGCCCG CCTGAACCGC GACGCAGCCC TGGAAGACGG GCCCCGCTTC 
GAGGTGACGC TGCTGCCCGA GCCATGCCGG ACGCCGGGCT CCCTGGGGGC CGTGTCCTCC 
GCGCTGGGCC GCGTCTCGGG CCTCGTGGGG CCGGTGAACC CCGCAGCCTG CCGGCCGGCT 
GAGCTACTAG CCCAGGAGGC GGGGGTGGCG CTGGTGCCCT GGAGCTGCCC GGGGACGCGG 
GCGGGGGGCA CCACAGCCCC CGCCGGGACG CCGGCGGCCG ATGCTCTGTA CGCCCTGCTC 
CGCGCCTTCC GCTGGGCGCG CGTGGCCCTA ATCACCGCGC CCCAGGACCT GTGGGTGGAG 
GCGGGACGCG CGCTGTCGGC GGCGCTCAGG GCCCGGGGTC TGCCCGTGGC GCTGGTGACC 
ACCATGGAGC CCTCGGACCT GTCTGGGGCC CGGGAGGCCC TGAGGAGGGT CCAGGACGGG 
CCCAGAGTCA GAGCGGTGAT CATGGTGATG CACTCGGTGC TGCTGGGCGG CGAGGAGCAG 
CGCTGTCTGC TGCAGGCTGC GGAAGAGCTG GGCCTGGCCG ATGGCTCCCT GGTCTTCCTG 
CCCTTCGACA CGCTCCACTA CGCCTTGTCC CCGGGCCCAG AGGCCTTGGC CGTGCTCGCC 
AACAGCTCAC AGCTGAGGAG GGCCCACGAT GCGGTGCTCA TCCTGACGCG TCACTGTCCC 
CCAGGGGGCA GCGTGATGGA CAACCTGCGC AGGGCCCAGG AGCACCAGGA GCTGCCCTCG 
GACCTAGATC TGCAGCAGGT GTCCCCGTTC TTCGGCACCA TCTACGACGC GGTCCTCCTG 
CTGGCGGGGG GCGTCGCACG GGCACGGGCG GCCGCAGGGG GCGGCTGGGT GTCGGGAGCC 
ACGGTAGCCC ACCACATCCC GGATGCCCAG GTCCCCGGCT TCTGTGGGAC CCTGGGAGGA 
GCCCAGGAGC CACCGTTTGT GCTGCTGGAC ACGGACGCGG CGGGGGACCG GCTCTTCGCC 
ACATACATGC TGGACCCCAC CCGGGGCTCC CTCCTCTCAG CTGGGACCCC CGTGCATTTC 
CCTAGAGGGG GAGGAACACC TGGGTCCGAC CCCTCATGCT GGTTCGAGCC AGGTGTCATC 
TGCAACGGAG GAGTGGAGCC CGGCCTCGTC TTTCTCGGCT TCCTCCTGGT GGTTGGGATG 
GGGCTGACTG GGGCGTTCCT GGCCCATTAT TTGAGGCATC GGCTACTTCA CATCCAAATG 
GTCTCTGGCC CCAACAAGAT CATCCTGACT CTGGACGATG TCACCTTTCT CCACCCGCAT 
GGGGGCAGCA CGCGAAAGGT GGTCCAGGGA AGTCGCTCGA GTCTGGCCGC CCGCAGTACA 
TCAGACATTC GCAGCGTCCC CAGCCAGCCC TTGGATAACT CCAACATTGG CCTCTTTGAA 
GGAGACTGGG TTTGGCTGAA GAAATTCCCC GGGGACCAGC ACATAGCCAT CCGCCCAGCA 
ACCAAGACGG CCTTCTCCAA GCTCCGGGAG CTCCGGCATG AGAACGTGGT GCTCTACCTG 
GGGCTCTTCC TCGGCAGCGG GGGAGCTGGT GGCTCGGCCG CGGGGGAAGG CGTGCTGGCC 
GTGGTCTCAG AGCACTGCGC CCGGGGCTCC CTCCACGACC TCCTCGCCCA AAGGGACATT 
AAGTTGGACT GGATGTTCAA GTCCTCCCTC CTGCTGGACC TCATCAAGGG AATGAGGTAT 
CTGCACCATC GAGGCGTGGC CCACGGGCGC CTGAAGTCGC GGAACTGCGT GGTGGACGGG 
AGGTTCGTGC TTAAGGTCAC GGATCACGGC CACGCGCGAC TAATGGAAGC TCAGAGGGTG 
TTACTGGAGC CTCCCAGCGC CGAGGACCAG CTATGGACAG CCCCGGAGCT GCTTCGGGAC 
CCGGCCCTGG AGCGCCGGGG AACGCTGCCC GGCGACGTCT TCAGCCTGGG CATCATCATG 
CAGGAGGTCG TGTGTCGCAG CGCCCCCTAT GCCATGCTGG AGCTCACTCC CGAGGAAGTG 
GTGGAGAGGG TGCGGAGCCC CCCTCCACTG TGCCGGCCCT CCGTGTCCAT GGACCAGGCA 
CCTGTGGAGT GCATTCAGCT GATGAAGCAG TGTTGGGCAG AGCACCCTGA TCTTCGGCCC 
TCCTTGGGCC ACATCTTCGA CCAGTTTAAA AGCATCAACA AGGGTCGGAA AACCAACATC 
ATTGACTCGA TGCTGAGGAT GCTGGAGCAG TACTCCAGTA ACCTGGAGGA CCTGATCCGG 
GAGCGGACGG AGGAGCTGGA GCTGGAAAAG CAGAAGACCG ACAGGCTACT CACGCAGATG 
CTGCCTCCTT CTGTGGCGGA GGCCCTGAAG ATGGGGACGC CGGTGGAGCC CGAGTATTTT 
GAGGAGGTGA CACTGTACTT CAGTGACATT GTGGGCTTCA CCACCATCTC AGCCATGAGT 
GAGCCCATCG AGGTGGTGGA TCTGCTCAAC GATCTCTACA CACTCTTCGA CGCCATCATT 
GGCTCCCACG ACGTCTACAA GGTGGAGACA ATCGGGGATG CCTACATGGT GGCCTCGGGG 
CTGCCACAGC GGAACGGGCA GCGACACGCC GCGGAGATCG CCAACATGGC CCTGGACATC 
CTCAGCGCCG TGGGCTCCTT CCGAATGCGT CACATGCCCG AAGTGCCCGT GCGCATTCGC 
ATTGGCCTGC ACTCGGGCCC GTGCGTGGCC GGCGTGGTGG GCCTCACCAT GCCACGGTAC 
TGCCTATTTG GGGACACGGT CAACACCGCC TCGCGCATGG AGTCCACGGG GCTGCCTTAC 
CGAATCCACG TGAACATGAG CACCGTGCGG ATTCTGCACG CTCTGGACGA GGGCTTCCAG 
ACGGAGGTGC GCGGCCGCAC GGAGCTGAAG GGCAAGGGCG CCGAAGACAC GTACTGGCTG 
GTGGGCAGAC GCGGCTTCAA CAAACCCATC CCCAAACCGC CCGACCTGCA ACCGGGCGCC 
AGCAACCATG GCATCAGTCT GCAGGAGATC CCTCTCGATC GGCGCTGGAA GCTGGAGAAG 
GCAAGGCCGG GCCAGTTCTC TGGAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003207.1
CDS	183..3512
Translation	MSACALLAGGLPDPRLCAPARWARSPPGVPGAPPWPQPRLRLLLLLLLLPPSALSAVFTVGVLGPWACDPIFARARPDLAARLAAARLNRDAALEDGPRFEVTLLPEPCRTPGSLGAVSSALGRVSGLVGPVNPAACRPAELLAQEAGVALVPWSCPGTRAGGTTAPAGTPAADALYALLRAFRWARVALITAPQDLWVEAGRALSAALRARGLPVALVTTMEPSDLSGAREALRRVQDGPRVRAVIMVMHSVLLGGEEQRCLLQAAEELGLADGSLVFLPFDTLHYALSPGPEALAVLANSSQLRRAHDAVLILTRHCPPGGSVMDNLRRAQEHQELPSDLDLQQVSPFFGTIYDAVLLLAGGVARARAAAGGGWVSGATVAHHIPDAQVPGFCGTLGGAQEPPFVLLDTDAAGDRLFATYMLDPTRGSLLSAGTPVHFPRGGGTPGSDPSCWFEPGVICNGGVEPGLVFLGFLLVVGMGLTGAFLAHYLRHRLLHIQMVSGPNKIILTLDDVTFLHPHGGSTRKVVQGSRSSLAARSTSDIRSVPSQPLDNSNIGLFEGDWVWLKKFPGDQHIAIRPATKTAFSKLRELRHENVVLYLGLFLGSGGAGGSAAGEGVLAVVSEHCARGSLHDLLAQRDIKLDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHARLMEAQRVLLEPPSAEDQLWTAPELLRDPALERRGTLPGDVFSLGIIMQEVVCRSAPYAMLELTPEEVVERVRSPPPLCRPSVSMDQAPVECIQLMKQCWAEHPDLRPSLGHIFDQFKSINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELELEKQKTDRLLTQMLPPSVAEALKMGTPVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMALDILSAVGSFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVRILHALDEGFQTEVRGRTELKGKGAEDTYWLVGRRGFNKPIPKPPDLQPGASNHGISLQEIPLDRRWKLEKARPGQFSGK

Target ORF information:

RefSeq Version	NM_001003207.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris guanylate cyclase 2D, retinal (GUCY2D), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003207.1

ORF Insert Sequence:

ATGAGCGCGT GCGCCCTCCT GGCGGGTGGG CTCCCCGACC CCCGGCTCTG CGCCCCCGCG 
CGGTGGGCTC GGTCCCCGCC CGGCGTCCCC GGGGCCCCGC CCTGGCCCCA GCCCCGGCTC 
CGGCTCCTGC TGCTGCTGCT CCTCCTGCCG CCCTCCGCCC TCTCCGCCGT CTTCACAGTC 
GGGGTGCTGG GCCCCTGGGC CTGCGACCCC ATCTTCGCCC GCGCCCGCCC GGACCTGGCC 
GCCCGCCTGG CCGCCGCCCG CCTGAACCGC GACGCAGCCC TGGAAGACGG GCCCCGCTTC 
GAGGTGACGC TGCTGCCCGA GCCATGCCGG ACGCCGGGCT CCCTGGGGGC CGTGTCCTCC 
GCGCTGGGCC GCGTCTCGGG CCTCGTGGGG CCGGTGAACC CCGCAGCCTG CCGGCCGGCT 
GAGCTACTAG CCCAGGAGGC GGGGGTGGCG CTGGTGCCCT GGAGCTGCCC GGGGACGCGG 
GCGGGGGGCA CCACAGCCCC CGCCGGGACG CCGGCGGCCG ATGCTCTGTA CGCCCTGCTC 
CGCGCCTTCC GCTGGGCGCG CGTGGCCCTA ATCACCGCGC CCCAGGACCT GTGGGTGGAG 
GCGGGACGCG CGCTGTCGGC GGCGCTCAGG GCCCGGGGTC TGCCCGTGGC GCTGGTGACC 
ACCATGGAGC CCTCGGACCT GTCTGGGGCC CGGGAGGCCC TGAGGAGGGT CCAGGACGGG 
CCCAGAGTCA GAGCGGTGAT CATGGTGATG CACTCGGTGC TGCTGGGCGG CGAGGAGCAG 
CGCTGTCTGC TGCAGGCTGC GGAAGAGCTG GGCCTGGCCG ATGGCTCCCT GGTCTTCCTG 
CCCTTCGACA CGCTCCACTA CGCCTTGTCC CCGGGCCCAG AGGCCTTGGC CGTGCTCGCC 
AACAGCTCAC AGCTGAGGAG GGCCCACGAT GCGGTGCTCA TCCTGACGCG TCACTGTCCC 
CCAGGGGGCA GCGTGATGGA CAACCTGCGC AGGGCCCAGG AGCACCAGGA GCTGCCCTCG 
GACCTAGATC TGCAGCAGGT GTCCCCGTTC TTCGGCACCA TCTACGACGC GGTCCTCCTG 
CTGGCGGGGG GCGTCGCACG GGCACGGGCG GCCGCAGGGG GCGGCTGGGT GTCGGGAGCC 
ACGGTAGCCC ACCACATCCC GGATGCCCAG GTCCCCGGCT TCTGTGGGAC CCTGGGAGGA 
GCCCAGGAGC CACCGTTTGT GCTGCTGGAC ACGGACGCGG CGGGGGACCG GCTCTTCGCC 
ACATACATGC TGGACCCCAC CCGGGGCTCC CTCCTCTCAG CTGGGACCCC CGTGCATTTC 
CCTAGAGGGG GAGGAACACC TGGGTCCGAC CCCTCATGCT GGTTCGAGCC AGGTGTCATC 
TGCAACGGAG GAGTGGAGCC CGGCCTCGTC TTTCTCGGCT TCCTCCTGGT GGTTGGGATG 
GGGCTGACTG GGGCGTTCCT GGCCCATTAT TTGAGGCATC GGCTACTTCA CATCCAAATG 
GTCTCTGGCC CCAACAAGAT CATCCTGACT CTGGACGATG TCACCTTTCT CCACCCGCAT 
GGGGGCAGCA CGCGAAAGGT GGTCCAGGGA AGTCGCTCGA GTCTGGCCGC CCGCAGTACA 
TCAGACATTC GCAGCGTCCC CAGCCAGCCC TTGGATAACT CCAACATTGG CCTCTTTGAA 
GGAGACTGGG TTTGGCTGAA GAAATTCCCC GGGGACCAGC ACATAGCCAT CCGCCCAGCA 
ACCAAGACGG CCTTCTCCAA GCTCCGGGAG CTCCGGCATG AGAACGTGGT GCTCTACCTG 
GGGCTCTTCC TCGGCAGCGG GGGAGCTGGT GGCTCGGCCG CGGGGGAAGG CGTGCTGGCC 
GTGGTCTCAG AGCACTGCGC CCGGGGCTCC CTCCACGACC TCCTCGCCCA AAGGGACATT 
AAGTTGGACT GGATGTTCAA GTCCTCCCTC CTGCTGGACC TCATCAAGGG AATGAGGTAT 
CTGCACCATC GAGGCGTGGC CCACGGGCGC CTGAAGTCGC GGAACTGCGT GGTGGACGGG 
AGGTTCGTGC TTAAGGTCAC GGATCACGGC CACGCGCGAC TAATGGAAGC TCAGAGGGTG 
TTACTGGAGC CTCCCAGCGC CGAGGACCAG CTATGGACAG CCCCGGAGCT GCTTCGGGAC 
CCGGCCCTGG AGCGCCGGGG AACGCTGCCC GGCGACGTCT TCAGCCTGGG CATCATCATG 
CAGGAGGTCG TGTGTCGCAG CGCCCCCTAT GCCATGCTGG AGCTCACTCC CGAGGAAGTG 
GTGGAGAGGG TGCGGAGCCC CCCTCCACTG TGCCGGCCCT CCGTGTCCAT GGACCAGGCA 
CCTGTGGAGT GCATTCAGCT GATGAAGCAG TGTTGGGCAG AGCACCCTGA TCTTCGGCCC 
TCCTTGGGCC ACATCTTCGA CCAGTTTAAA AGCATCAACA AGGGTCGGAA AACCAACATC 
ATTGACTCGA TGCTGAGGAT GCTGGAGCAG TACTCCAGTA ACCTGGAGGA CCTGATCCGG 
GAGCGGACGG AGGAGCTGGA GCTGGAAAAG CAGAAGACCG ACAGGCTACT CACGCAGATG 
CTGCCTCCTT CTGTGGCGGA GGCCCTGAAG ATGGGGACGC CGGTGGAGCC CGAGTATTTT 
GAGGAGGTGA CACTGTACTT CAGTGACATT GTGGGCTTCA CCACCATCTC AGCCATGAGT 
GAGCCCATCG AGGTGGTGGA TCTGCTCAAC GATCTCTACA CACTCTTCGA CGCCATCATT 
GGCTCCCACG ACGTCTACAA GGTGGAGACA ATCGGGGATG CCTACATGGT GGCCTCGGGG 
CTGCCACAGC GGAACGGGCA GCGACACGCC GCGGAGATCG CCAACATGGC CCTGGACATC 
CTCAGCGCCG TGGGCTCCTT CCGAATGCGT CACATGCCCG AAGTGCCCGT GCGCATTCGC 
ATTGGCCTGC ACTCGGGCCC GTGCGTGGCC GGCGTGGTGG GCCTCACCAT GCCACGGTAC 
TGCCTATTTG GGGACACGGT CAACACCGCC TCGCGCATGG AGTCCACGGG GCTGCCTTAC 
CGAATCCACG TGAACATGAG CACCGTGCGG ATTCTGCACG CTCTGGACGA GGGCTTCCAG 
ACGGAGGTGC GCGGCCGCAC GGAGCTGAAG GGCAAGGGCG CCGAAGACAC GTACTGGCTG 
GTGGGCAGAC GCGGCTTCAA CAAACCCATC CCCAAACCGC CCGACCTGCA ACCGGGCGCC 
AGCAACCATG GCATCAGTCT GCAGGAGATC CCTCTCGATC GGCGCTGGAA GCTGGAGAAG 
GCAAGGCCGG GCCAGTTCTC TGGAAAGTGA