Gene Symbol | nhr-25 |
Entrez Gene ID | 181432 |
Full Name | Nuclear hormone receptor family member nhr-25 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » nhr-25 cDNA ORF clone
Gene Symbol | nhr-25 |
Entrez Gene ID | 181432 |
Full Name | Nuclear hormone receptor family member nhr-25 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001029379.2 | NP_001024550.1 | Nuclear hormone receptor family member nhr-25 |
NM_001029380.3 | NP_001024551.1 | Nuclear hormone receptor family member nhr-25 |
NM_001029380.5 | NP_001024551.1 | Nuclear hormone receptor family member nhr-25 |
NM_001029379.3 | NP_001024550.1 | Nuclear hormone receptor family member nhr-25 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
An environment-microorganism-host metabolic axis regulates host mitochondrial dynamics and lipid metabolism via nhr25/GRL-21/PTR-24 signaling.
Title: Microbial metabolites regulate host lipid metabolism through NR5A-Hedgehog signalling.
these data indicate that inactivation of either acs-3 or nhr-25 causes stress sensitivity and increased expression of innate immunity/stress genes, most likely by different mechanisms.
Title: Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses.
Functional validation of a subset of the target genes showed both activating and inhibitory roles of NHR-25 and ELT-3 in regulating their targets.
Title: Collaborative regulation of development but independent control of metabolism by two epidermis-specific transcription factors in Caenorhabditis elegans.
We conclude that sumoylation operates at multiple levels to affect NHR-25 activity in a highly coordinated spatial and temporal manner
Title: Sumoylated NHR-25/NR5A regulates cell fate during C. elegans vulval development.
ACS-3-derived long-chain fatty acyl-CoAs, perhaps incorporated into complex ligands such as phosphoinositides, modulate NHR-25 function, which in turn regulates an endocrine program of lipid uptake and synthesis.
Title: Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25.
The following nhr-25 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the nhr-25 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa349011 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029380.3 , NM_001029380.5 | |
Accession Version | NM_001029380.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-25 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_001029380.2. COMPLETENESS: incomplete on both ends. |
1 | ATGGGAATGA AAATGGAAGC GGTGCGTGCC GATAGGATGA GAGGTGGACG AAACAAGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024551.1 |
CDS | 1..1479 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029380.3 |
1 | ATGGGAATGA AAATGGAAGC GGTGCGTGCC GATAGGATGA GAGGTGGACG AAACAAGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349011 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029380.3 , NM_001029380.5 | |
Accession Version | NM_001029380.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-25 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_001029380.4. |
1 | ATGGGAATGA AAATGGAAGC GGTGCGTGCC GATAGGATGA GAGGTGGACG AAACAAGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024551.1 |
CDS | 124..1602 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029380.5 |
1 | ATGGGAATGA AAATGGAAGC GGTGCGTGCC GATAGGATGA GAGGTGGACG AAACAAGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa350149 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029379.2 , NM_001029379.3 | |
Accession Version | NM_001029379.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-25 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_001029379.1. COMPLETENESS: incomplete on both ends. |
1 | ATGACTGACG TCGAGAGGAT GGTTCTGCGA CCGAATCATG AAGGCGAGAT GTGCCCGGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024550.1 |
CDS | 1..1719 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029379.2 |
1 | ATGACTGACG TCGAGAGGAT GGTTCTGCGA CCGAATCATG AAGGCGAGAT GTGCCCGGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa350149 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029379.2 , NM_001029379.3 | |
Accession Version | NM_001029379.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Nuclear hormone receptor family member nhr-25 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Sep 4, 2019 this sequence version replaced NM_001029379.2. |
1 | ATGACTGACG TCGAGAGGAT GGTTCTGCGA CCGAATCATG AAGGCGAGAT GTGCCCGGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024550.1 |
CDS | 103..1821 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029379.3 |
1 | ATGACTGACG TCGAGAGGAT GGTTCTGCGA CCGAATCATG AAGGCGAGAT GTGCCCGGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |