Gene Symbol | sas-6 |
Entrez Gene ID | 178345 |
Full Name | Spindle assembly abnormal protein 6 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » sas-6 cDNA ORF clone
Gene Symbol | sas-6 |
Entrez Gene ID | 178345 |
Full Name | Spindle assembly abnormal protein 6 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_070259.5 | NP_502660.1 | Spindle assembly abnormal protein 6 |
NM_070259.6 | NP_502660.1 | Spindle assembly abnormal protein 6 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Direct interactions of the SAS-6 coiled coil with ZYG-1 and SAS-5 are required to recruit SAS-6 to the mother centriole.
Title: Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly.
It was demonstrated that the short SAS-5 C-terminal domain (residues 390-404) specifically binds to a narrow central region (residues 275-288) of the SAS-6 coiled coil.
Title: SAS-6 coiled-coil structure and interaction with SAS-5 suggest a regulatory mechanism in C. elegans centriole assembly.
Study demonstrates that the kinase ZYG-1 phosphorylates the coiled-coil protein SAS-6 at serine 123 in vitro; this phosphorylation event is crucial for centriole formation in vivo.
Title: Phosphorylation of SAS-6 by ZYG-1 is critical for centriole formation in C. elegans embryos.
SAS-6 is a component that is required for daughter centriole formation in C. elegans. SAS-6 is a coiled-coil protein that is recruited to centrioles at the onset of the centrosome duplication cycle.
Title: SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells.
The following sas-6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sas-6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa342739 | |
Clone ID Related Accession (Same CDS sequence) | NM_070259.5 , NM_070259.6 | |
Accession Version | NM_070259.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Spindle assembly abnormal protein 6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_070259.4. COMPLETENESS: incomplete on both ends. |
1 | ATGACTAGCA AAATTGCATT ATTCGATCAA ACACTCATCG CCTCACTTCT ACAGCCGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_502660.1 |
CDS | 1..1479 |
Translation |
Target ORF information:
Target ORF information:
|
NM_070259.5 |
1 | ATGACTAGCA AAATTGCATT ATTCGATCAA ACACTCATCG CCTCACTTCT ACAGCCGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342739 | |
Clone ID Related Accession (Same CDS sequence) | NM_070259.5 , NM_070259.6 | |
Accession Version | NM_070259.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Spindle assembly abnormal protein 6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_070259.5. |
1 | ATGACTAGCA AAATTGCATT ATTCGATCAA ACACTCATCG CCTCACTTCT ACAGCCGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_502660.1 |
CDS | 23..1501 |
Translation |
Target ORF information:
Target ORF information:
|
NM_070259.6 |
1 | ATGACTAGCA AAATTGCATT ATTCGATCAA ACACTCATCG CCTCACTTCT ACAGCCGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |